3NZKA

Structure of lpxc from yersinia enterocolitica complexed with chir090 inhibitor
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
298
structure length
298
Chain Sequence
MIKQRTLKRIVQATGVGLHTGKKVTLTMRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIIIEVNAPEVPIMDGSASPFVYLLLDAGIEELNSAKKFLRLKETVRVEDGDKWAELSPFNGFRLDFTIDFNHPAIDSSTQRYRLDFSADSFVRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEFVTFQDEAEMPLAFK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Metal-Dependent Deacetylase LpxC from Yersinia enterocolitica Complexed with the Potent Inhibitor CHIR-090 .
pubmed doi rcsb
molecule tags Hydrolase
source organism Yersinia enterocolitica
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 94
structure length 298
sequence length 298
chains with identical sequence B
ec nomenclature ec 3.5.1.33: N-acetylglucosamine deacetylase.
pdb deposition date 2010-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 3nzkA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 3nzkA02
4LCHA 2J65A 3U1YA 1YHCA 2IERA 3NZKA 1P42A 2O3ZA 4FW4A 5DRPA 3P3GA 3PS3A 3PS2A 3P3CA 3UHMA 4ISAA 4LCFA 5DRRA 3PS1A 4MQYA 4U3DA 3P76A 2VESA 2IESA 4FW3A 4MDTA 4OZEA 4J3DA 5DROA 2GO3A 3P3EA 4LCGA 1YH8A 1XXEA 2JT2A 4IS9A 4OKGA 5DRQA 4FW5A 2GO4A 4FW7A 4FW6A 4U3BA
chains in the Genus database with same CATH superfamily
1Z0VA 4AIDA 2UUBI 2UXCE 4DV4E 1ZXNA 3KRNA 4BA2B 1NZ0A 4JYAI 1B62A 3Q6MA 4IFDD 4LFCI 4GKKE 4AQYE 2F1DA 2VESA 4JI8E 1Z0BA 1OJ4A 2C39B 4GQUA 4DR5I 1J5EE 4DR4E 2BA0D 5GMEA 4JI2I 2NN6B 4X62I 5C0XA 4MU4A 3OTOE 1Z0TA 4FW7A 4JG4A 1UDQA 1QZRA 2DEIA 4MU3A 1D6TA 3HULA 1HR0E 4DR6E 2X7IA 3NZKA 4GKJI 4Z7YA 4MYUA 4IZKB 4LCFA 3QT8A 4LF7I 1R6MA 4IZJA 4MQYA 4JI4I 3D4JA 3WU5A 1Z5AA 3T1YI 4MDTA 4JI7E 5DNXA 4DU8A 3J80C 2JT2A 4LF5I 4DV4I 1ZM2A 4IFDA 3H1CA 4P7AA 4BA1A 4LCHA 4USKA 5GMDA 2J7KA 3B78A 1YHCA 2IOPA 1USUA 3LTOA 2WNRA 5ELWA 4JI5E 2UXDE 5C0XC 4JI8I 4HYMA 1Z5BA 4LF6E 3ZZTA 4JI6I 2BR2A 4DR4I 5K36F 3K85A 3J80Q 4LF8I 2ZM6E 3OTOI 4DU7A 2E5LE 4DR6I 2GO4A 2Z5CB 3K17A 3JAMC 2O1VA 1HNXE 3J81C 4DV3I 4OO1E 1N36I 5K36E 4U3BA 3CDIA 1EA6A 4FW4A 3PYFA 3ZKDA 1PVGA 2JEAB 4DUYI 5DRRA 2UUBE 4WUDA 3B4TA 2V2ZA 4U3DA 2EFGA 5FLXQ 2PNZA 2BM1A 2JE6B 2V34A 3F0NA 3PRYA 5EKWA 4BA2A 4JYAE 3HJCA 2BA1D 4USMA 2VQFI 4DR3I 5JEAF 3PYEA 4LFCE 2O1TA 3ZKBA 1Y6ZA 4DPTA 4HY1A 1RHYA 2UUCI 2LJPA 1DARA 2C39A 2VF3A 2O1UA 2VQEI 5JEAE 4JI2E 4X62E 2ZBKB 4DPYA 4ISAA 2NN6E 4NXNI 1XNQI 2ZM6I 3WU6A 3P76A 4GKJE 4QNJA 4OO1B 2E5LI 5K36B 4IZKA 2A2DA 4P52A 4JI4E 4I3HA 1Y4SA 3T1YE 1OYRA 5EL9A 4IZJD 3ZZUA 1E3HA 1BKNA 1H7SA 1FJGE 3LPSA 3U1YA 3P06A 4DV1E 4LF5E 3PS3A 2XEXA 4LF9I 2V2QA 3M7NG 4HACB 4PRVA 1Y60A 5JEAB 1YH8A 4JI6E 1IBLE 1HNWE 5DRQA 3GONA 1VISA 4PRXA 1IBMI 4LF8E 3J7AM 3GLLA 1KKHA 4FWHA 1VI7A 4DPXA 1Z0WA 4LFAI 2JEBB 1USVA 4FW9A 1N34E 4DV3E 2C37B 1H74A 1N36E 2Z5CA 4OO1D 5C0XF 5K36D 1MU5A 2IESA 1NHIA 4DUYE 2AJ4A 4B3TE 2JEAA 2PO1B 1I94I 1FJGI 2X36A 1XXEA 4LFBI 4DV1I 3Q6NA 2JE6A 2VQFE 4DR3E 2PNLA 5FWKA 4DR1E 2PO2B 1H73A 1B63A 2O3ZA 1S16A 2IOQA 2UUCE 3K1JA 4QNKA 5DNLA 3QT5A 2VQEE 4AM3A 1Z5CA 1HK7A 1HNWI 2HK3A 1IBLI 4DV0I 5JEAD 1UDNA 1Y4UA 4NXNE 1XNQE 3M85G 4K0KE 5FLXC 4LCGA 2NN6D 4LPFA 4AIMA 4OO1A 4MYTA 5K36A 2A2CA 1N34I 3B8HA 1H7UA 4DPWA 1KTVA 2CG9A 1P42A 1R6LA 4WUCA 3GMEA 4WUBA 4B3TI 4IFDC 2C38B 2NPFA 4DV2I 1Z0CA 4UTGA 4B3RE 4LF9E 4KHPI 1WUUA 5IT9C 4PU9A 4JI1I 3CDJA 4FW5A 1Z0EA 1Y5YA 1H72C 4HACA 3ZM7A 4DR1I 1ZM4A 2ZITA 2O1WA 5LMNE 2J65A 2Z5BB 5JEAA 2IERA 1KVKA 1IBME 4JI0E 5DRPA 5LMUI 4B3SE 4DR2E 2NN6A 3M6AA 4DV7E 4N3OA 4K0KI 4LFAE 1RREA 4YHHI 1N0UA 1N33E 3LNUA 4BA1B 5IT9Q 3DD6A 1IBKI 3GCMA 3H4LA 2GQ0A 4OKGA 4DUZI 2HHHI 4OX9E 2V8PA 1PIEA 2OI2A 3QT6A 1I94E 2BR2B 4LFBE 2F4VE 4JI3E 4DV5E 1XMQI 2UU9I 4B3RI 4EMDA 4NXMI 4DPUA 2WW4A 2GS8A 4X64I 2WP8B 2PO2A 2DEJA 1ELOA 1FWLA 4FWGA 4ED4A 3P3EA 1UDSA 2NN6C 1OYSA 3M7ND 3L7ZB 4XTJA 2UUAE 4IS9A 5LMNI 4DV0E 4DXLA 2AE8A 4JI0I 4FW6A 4B3MI 4B3SI 4DR2I 2PNZB 4DV7I 2V2VA 2BV3A 5A2QC 3PS2A 1N33I 3UHMA 4NBQA 3V2UC 1ZXMA 1EI1A 5IWAI 2E1RA 1NHJA 2BA0G 1XNRE 3PYDA 1XMOE 5L3JA 4R1FA 4OX9I 1FNMA 1N0VC 5DROA 2PNMA 1UEKA 1MG7A 3ZZ0A 4DV2E 2C38A 4LF4E 2F4VI 4JI3I 5C0XE 4DV5I 4KHPE 4JV5I 4X65E 5A2QQ 3WU3A 2PO0B 4JI1E 1E3PA 3QT7A 4ZVIA 1HNZE 4DV6I 2UXBE 1Z59A 3PS1A 4UT4A 2R3VA 4FN5A 2Z5BA 4IFDF 5BR8I 1FWKA 2CGEA 2UUAI 5LMUE 4X66E 5LL6R 1A6FA 1RR9A 2UXCI 3T1HE 2CZ9A 4YHHE 4MU1A 4IFDE 1ZM3A 3M85D 1IBKE 2R42A 2HHHE 4DUZE 4AQYI 4GKKI 1Z0GA 2HFSA 1XNRI 1XMOI 1U2RA 4YY3E 3U1KA 1J5EI 1S4EA 1XMQE 4OO1F 5C0XB 4LF4I 2UU9E 2GO3A 4NXME 1NHHA 2HKEA 4KQVA 4X64E 4DR7E 4X65I 1HR0I 4M1KA 1N32E 2WP8A 1FKAE 2HKJA 2HFUA 4IZJB 3PYGA 1HNZI 1K47A 2UXBI 3L7ZA 3P3GA 4B3ME 4JI7I 2BA1G 1FI4A 4X66I 4URLA 4OO1C 3CWVA 5K36C 4IFDB 3T1HI 2Q2EB 2JEBA 4FWDA 4OZEA 2BM0A 4J3DA 2C37A 3JAMQ 3WU4A 5IWAE 1ZM9A 3J81Q 1XHKA 2NN6F 2HK2A 2WNRB 2CVEA 4DR5E 2Z5EA 4JI5I 2UXDI 4YY3I 2PO1A 4LF6I 4LOMA 3B82A 3P3CA 3Q1QA 4JV5E 5C0XD 4RPFA 2PO0A 3J7AG 4DR7I 1UDOA 4FW3A 4Z7CA 1MX0A 5JEAC 3V5RA 4DV6E 3HKMA 4MU0A 4LF7E 1HNXI 1N32I 1PKPA 1KIJA 5BR8E 4HXZA 1OYPA
chains in the Genus database with same CATH topology
4LCHA 2J65A 3U1YA 1YHCA 2IERA 3NZKA 1P42A 2O3ZA 4FW4A 5DRPA 3P3GA 3PS3A 3PS2A 3P3CA 3UHMA 4ISAA 4LCFA 5DRRA 3PS1A 4MQYA 4U3DA 3P76A 2VESA 2IESA 4FW3A 4MDTA 4OZEA 4J3DA 5DROA 2GO3A 3P3EA 4LCGA 1YH8A 1XXEA 2JT2A 4IS9A 4OKGA 5DRQA 4FW5A 2GO4A 4FW7A 4FW6A 4U3BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LCH A;  2J65 A;  3U1Y A;  1YHC A;  2IER A;  3NZK A;  1P42 A;  2O3Z A;  4FW4 A;  5DRP A;  3P3G A;  3PS3 A;  3PS2 A;  3P3C A;  3UHM A;  4ISA A;  4LCF A;  5DRR A;  3PS1 A;  4MQY A;  4U3D A;  3P76 A;  2VES A;  2IES A;  4FW3 A;  4MDT A;  4OZE A;  4J3D A;  5DRO A;  2GO3 A;  3P3E A;  4LCG A;  1YH8 A;  1XXE A;  2JT2 A;  4IS9 A;  4OKG A;  5DRQ A;  4FW5 A;  2GO4 A;  4FW7 A;  4FW6 A;  4U3B A; 
#chains in the Genus database with same CATH topology
 1Z0V A;  4AID A;  2UUB I;  2UXC E;  4DV4 E;  1ZXN A;  3KRN A;  4BA2 B;  1NZ0 A;  4JYA I;  1B62 A;  3Q6M A;  4IFD D;  4LFC I;  4GKK E;  4AQY E;  2F1D A;  2VES A;  4JI8 E;  1Z0B A;  1OJ4 A;  2C39 B;  4GQU A;  4DR5 I;  1J5E E;  4DR4 E;  2BA0 D;  5GME A;  4JI2 I;  2NN6 B;  4X62 I;  5C0X A;  4MU4 A;  3OTO E;  1Z0T A;  4FW7 A;  4JG4 A;  1UDQ A;  1QZR A;  2DEI A;  4MU3 A;  1D6T A;  3HUL A;  1HR0 E;  4DR6 E;  2X7I A;  3NZK A;  4GKJ I;  4Z7Y A;  4MYU A;  4IZK B;  4LCF A;  3QT8 A;  4LF7 I;  1R6M A;  4IZJ A;  4MQY A;  4JI4 I;  3D4J A;  3WU5 A;  1Z5A A;  3T1Y I;  4MDT A;  4JI7 E;  5DNX A;  4DU8 A;  3J80 C;  2JT2 A;  4LF5 I;  4DV4 I;  1ZM2 A;  4IFD A;  3H1C A;  4P7A A;  4BA1 A;  4LCH A;  4USK A;  5GMD A;  2J7K A;  3B78 A;  1YHC A;  2IOP A;  1USU A;  3LTO A;  2WNR A;  5ELW A;  4JI5 E;  2UXD E;  5C0X C;  4JI8 I;  4HYM A;  1Z5B A;  4LF6 E;  3ZZT A;  4JI6 I;  2BR2 A;  4DR4 I;  5K36 F;  3K85 A;  3J80 Q;  4LF8 I;  2ZM6 E;  3OTO I;  4DU7 A;  2E5L E;  4DR6 I;  2GO4 A;  2Z5C B;  3K17 A;  3JAM C;  2O1V A;  1HNX E;  3J81 C;  4DV3 I;  4OO1 E;  1N36 I;  5K36 E;  4U3B A;  3CDI A;  1EA6 A;  4FW4 A;  3PYF A;  3ZKD A;  1PVG A;  2JEA B;  4DUY I;  5DRR A;  2UUB E;  4WUD A;  3B4T A;  2V2Z A;  4U3D A;  2EFG A;  5FLX Q;  2PNZ A;  2BM1 A;  2JE6 B;  2V34 A;  3F0N A;  3PRY A;  5EKW A;  4BA2 A;  4JYA E;  3HJC A;  2BA1 D;  4USM A;  2VQF I;  4DR3 I;  5JEA F;  3PYE A;  4LFC E;  2O1T A;  3ZKB A;  1Y6Z A;  4DPT A;  4HY1 A;  1RHY A;  2UUC I;  2LJP A;  1DAR A;  2C39 A;  2VF3 A;  2O1U A;  2VQE I;  5JEA E;  4JI2 E;  4X62 E;  2ZBK B;  4DPY A;  4ISA A;  2NN6 E;  4NXN I;  1XNQ I;  2ZM6 I;  3WU6 A;  3P76 A;  4GKJ E;  4QNJ A;  4OO1 B;  2E5L I;  5K36 B;  4IZK A;  2A2D A;  4P52 A;  4JI4 E;  4I3H A;  1Y4S A;  3T1Y E;  1OYR A;  5EL9 A;  4IZJ D;  3ZZU A;  1E3H A;  1BKN A;  1H7S A;  1FJG E;  3LPS A;  3U1Y A;  3P06 A;  4DV1 E;  4LF5 E;  3PS3 A;  2XEX A;  4LF9 I;  2V2Q A;  3M7N G;  4HAC B;  4PRV A;  1Y60 A;  5JEA B;  1YH8 A;  4JI6 E;  1IBL E;  1HNW E;  5DRQ A;  3GON A;  1VIS A;  4PRX A;  1IBM I;  4LF8 E;  3J7A M;  3GLL A;  1KKH A;  4FWH A;  1VI7 A;  4DPX A;  1Z0W A;  4LFA I;  2JEB B;  1USV A;  4FW9 A;  1N34 E;  4DV3 E;  2C37 B;  1H74 A;  1N36 E;  2Z5C A;  4OO1 D;  5C0X F;  5K36 D;  1MU5 A;  2IES A;  1NHI A;  4DUY E;  2AJ4 A;  4B3T E;  2JEA A;  2PO1 B;  1I94 I;  1FJG I;  2X36 A;  1XXE A;  4LFB I;  4DV1 I;  3Q6N A;  2JE6 A;  2VQF E;  4DR3 E;  2PNL A;  5FWK A;  4DR1 E;  2PO2 B;  1H73 A;  1B63 A;  2O3Z A;  1S16 A;  2IOQ A;  2UUC E;  3K1J A;  4QNK A;  5DNL A;  3QT5 A;  2VQE E;  4AM3 A;  1Z5C A;  1HK7 A;  1HNW I;  2HK3 A;  1IBL I;  4DV0 I;  5JEA D;  1UDN A;  1Y4U A;  4NXN E;  1XNQ E;  3M85 G;  4K0K E;  5FLX C;  4LCG A;  2NN6 D;  4LPF A;  4AIM A;  4OO1 A;  4MYT A;  5K36 A;  2A2C A;  1N34 I;  3B8H A;  1H7U A;  4DPW A;  1KTV A;  2CG9 A;  1P42 A;  1R6L A;  4WUC A;  3GME A;  4WUB A;  4B3T I;  4IFD C;  2C38 B;  2NPF A;  4DV2 I;  1Z0C A;  4UTG A;  4B3R E;  4LF9 E;  4KHP I;  1WUU A;  5IT9 C;  4PU9 A;  4JI1 I;  3CDJ A;  4FW5 A;  1Z0E A;  1Y5Y A;  1H72 C;  4HAC A;  3ZM7 A;  4DR1 I;  1ZM4 A;  2ZIT A;  2O1W A;  5LMN E;  2J65 A;  2Z5B B;  5JEA A;  2IER A;  1KVK A;  1IBM E;  4JI0 E;  5DRP A;  5LMU I;  4B3S E;  4DR2 E;  2NN6 A;  3M6A A;  4DV7 E;  4N3O A;  4K0K I;  4LFA E;  1RRE A;  4YHH I;  1N0U A;  1N33 E;  3LNU A;  4BA1 B;  5IT9 Q;  3DD6 A;  1IBK I;  3GCM A;  3H4L A;  2GQ0 A;  4OKG A;  4DUZ I;  2HHH I;  4OX9 E;  2V8P A;  1PIE A;  2OI2 A;  3QT6 A;  1I94 E;  2BR2 B;  4LFB E;  2F4V E;  4JI3 E;  4DV5 E;  1XMQ I;  2UU9 I;  4B3R I;  4EMD A;  4NXM I;  4DPU A;  2WW4 A;  2GS8 A;  4X64 I;  2WP8 B;  2PO2 A;  2DEJ A;  1ELO A;  1FWL A;  4FWG A;  4ED4 A;  3P3E A;  1UDS A;  2NN6 C;  1OYS A;  3M7N D;  3L7Z B;  4XTJ A;  2UUA E;  4IS9 A;  5LMN I;  4DV0 E;  4DXL A;  2AE8 A;  4JI0 I;  4FW6 A;  4B3M I;  4B3S I;  4DR2 I;  2PNZ B;  4DV7 I;  2V2V A;  2BV3 A;  5A2Q C;  3PS2 A;  1N33 I;  3UHM A;  4NBQ A;  3V2U C;  1ZXM A;  1EI1 A;  5IWA I;  2E1R A;  1NHJ A;  2BA0 G;  1XNR E;  3PYD A;  1XMO E;  5L3J A;  4R1F A;  4OX9 I;  1FNM A;  1N0V C;  5DRO A;  2PNM A;  1UEK A;  1MG7 A;  3ZZ0 A;  4DV2 E;  2C38 A;  4LF4 E;  2F4V I;  4JI3 I;  5C0X E;  4DV5 I;  4KHP E;  4JV5 I;  4X65 E;  5A2Q Q;  3WU3 A;  2PO0 B;  4JI1 E;  1E3P A;  3QT7 A;  4ZVI A;  1HNZ E;  4DV6 I;  2UXB E;  1Z59 A;  3PS1 A;  4UT4 A;  2R3V A;  4FN5 A;  2Z5B A;  4IFD F;  5BR8 I;  1FWK A;  2CGE A;  2UUA I;  5LMU E;  4X66 E;  5LL6 R;  1A6F A;  1RR9 A;  2UXC I;  3T1H E;  2CZ9 A;  4YHH E;  4MU1 A;  4IFD E;  1ZM3 A;  3M85 D;  1IBK E;  2R42 A;  2HHH E;  4DUZ E;  4AQY I;  4GKK I;  1Z0G A;  2HFS A;  1XNR I;  1XMO I;  1U2R A;  4YY3 E;  3U1K A;  1J5E I;  1S4E A;  1XMQ E;  4OO1 F;  5C0X B;  4LF4 I;  2UU9 E;  2GO3 A;  4NXM E;  1NHH A;  2HKE A;  4KQV A;  4X64 E;  4DR7 E;  4X65 I;  1HR0 I;  4M1K A;  1N32 E;  2WP8 A;  1FKA E;  2HKJ A;  2HFU A;  4IZJ B;  3PYG A;  1HNZ I;  1K47 A;  2UXB I;  3L7Z A;  3P3G A;  4B3M E;  4JI7 I;  2BA1 G;  1FI4 A;  4X66 I;  4URL A;  4OO1 C;  3CWV A;  5K36 C;  4IFD B;  3T1H I;  2Q2E B;  2JEB A;  4FWD A;  4OZE A;  2BM0 A;  4J3D A;  2C37 A;  3JAM Q;  3WU4 A;  5IWA E;  1ZM9 A;  3J81 Q;  1XHK A;  2NN6 F;  2HK2 A;  2WNR B;  2CVE A;  4DR5 E;  2Z5E A;  4JI5 I;  2UXD I;  4YY3 I;  2PO1 A;  4LF6 I;  4LOM A;  3B82 A;  3P3C A;  3Q1Q A;  4JV5 E;  5C0X D;  4RPF A;  2PO0 A;  3J7A G;  4DR7 I;  1UDO A;  4FW3 A;  4Z7C A;  1MX0 A;  5JEA C;  3V5R A;  4DV6 E;  3HKM A;  4MU0 A;  4LF7 E;  1HNX I;  1N32 I;  1PKP A;  1KIJ A;  5BR8 E;  4HXZ A;  1OYP A; 
#chains in the Genus database with same CATH homology
 4LCH A;  2J65 A;  3U1Y A;  1YHC A;  2IER A;  3NZK A;  1P42 A;  2O3Z A;  4FW4 A;  5DRP A;  3P3G A;  3PS3 A;  3PS2 A;  3P3C A;  3UHM A;  4ISA A;  4LCF A;  5DRR A;  3PS1 A;  4MQY A;  4U3D A;  3P76 A;  2VES A;  2IES A;  4FW3 A;  4MDT A;  4OZE A;  4J3D A;  5DRO A;  2GO3 A;  3P3E A;  4LCG A;  1YH8 A;  1XXE A;  2JT2 A;  4IS9 A;  4OKG A;  5DRQ A;  4FW5 A;  2GO4 A;  4FW7 A;  4FW6 A;  4U3B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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