4FW6 | Genus

Total Genus 88

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	88
sequence length	300
structure length	300
Chain Sequence	AMIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRP

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase/hydrolase inhibitor
source organism	Pseudomonas aeruginosa
publication title	Crystal Structure of the LpxC rcsb
molecule keywords	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus	88
structure length	300
sequence length	300
chains with identical sequence	B, C, D
ec nomenclature	ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date	2012-06-29

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF03331	LpxC	UDP-3-O-acyl N-acetylglycosamine deacetylase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.230.20	Alpha Beta	2-Layer Sandwich	Ribosomal Protein S5; domain 2	lpxc deacetylase, domain 1	4fw6A01
3.30.1700.10	Alpha Beta	2-Layer Sandwich	lpxc deacetylase, domain 1	lpxc deacetylase, domain 2	4fw6A02

4LCGA 2IERA 3P3CA 4FW3A 5DRQA 2IESA 2O3ZA 4FW6A 4MDTA 3PS1A 4U3DA 3U1YA 2JT2A 5DROA 5DRPA 3NZKA 4MQYA 2VESA 4OKGA 1YHCA 2GO4A 3UHMA 3PS3A 4ISAA 2GO3A 4FW7A 4FW4A 4OZEA 1P42A 1YH8A 3P3GA 1XXEA 3P76A 4IS9A 4LCHA 3P3EA 5DRRA 4FW5A 4J3DA 2J65A 4LCFA 4U3BA 3PS2A
chains in the Genus database with same CATH superfamily

3HKMA 2C38A 4AM3A 4JI3E 2A2DA 1NZ0A 4JI8E 3DD6A 1N36I 1RHYA 1H7UA 4X62E 3T1YI 2VESA 3D4JA 2UUAI 3UHMA 4JI2I 4DV2E 3V2UC 5IWAE 3Q1QA 4PU9A 1H7SA 1VISA 4DPXA 4AIDA 1FNMA 2V2QA 4K0KI 4FW5A 4BA1A 4DR2I 2BA0D 4PRXA 4IZJA 5K36B 4WUBA 1ZM2A 1N32I 1ZM3A 1XNQI 4USKA 3M6AA 1E3PA 4FW9A 1PKPA 4KQVA 3JAMQ 1KIJA 3PYFA 4DV6E 2NN6E 4IZJD 3K1JA 1E3HA 4JI4E 3JAMC 3PYDA 4N3OA 2O1WA 3WU6A 3OTOI 2WP8B 1ZXMA 4FWHA 4JI5E 3WU4A 4LPFA 4UTGA 4DR5I 3GMEA 4PRVA 4X64I 4IFDC 1XMOE 3CDIA 4B3RE 3P3CA 4OO1C 4WUDA 1I94E 3M7NG 2F1DA 2V8PA 5K36E 5JEAF 4DV7E 2IOPA 2PO0A 2Z5BB 2UXCE 3LTOA 2R42A 1XHKA 5A2QQ 4GQUA 4B3TE 2HFUA 2E1RA 5A2QC 1IBKE 4U3BA 2JEBB 4YY3E 3PS2A 2JEAB 2HFSA 4M1KA 4ED4A 1FJGI 2V2VA 2NN6A 1IBMI 1U2RA 3K17A 4FWGA 4AIMA 1USVA 1H72C 4DR6I 1OYRA 2X36A 1XNRE 2NN6D 5LMNE 4YHHE 4LF5E 2GO3A 4DR4E 4OZEA 1YH8A 4X65I 4QNKA 2E5LE 1XMQI 1OJ4A 1HNZI 2CZ9A 3ZKDA 4Z7CA 3M85G 1HK7A 2VF3A 2O1VA 4HY1A 1IBLI 3L7ZB 5LL6R 2CGEA 2UXBE 3U1YA 4UT4A 1Z0GA 5JEAC 4DV3E 1IBLE 3GLLA 2XEXA 2UUCE 4NXMI 2UU9E 4X66E 5C0XC 4JI6I 1OYPA 4LFAI 4FW7A 4JG4A 4LFBI 4JV5I 4AQYE 4LF9E 2WP8A 3QT7A 1R6MA 4NBQA 4IFDF 4DV4I 4LFCE 1HR0E 3PYGA 4OO1F 2BA1D 3NZKA 1K47A 1FWKA 1N33I 1NHIA 1Z5BA 1N36E 3T1YE 2V2ZA 4FW4A 1Z5CA 2VQFI 1XXEA 2UUAE 4LCHA 2HK2A 1KKHA 2Z5BA 4JI2E 4JI7I 3QT6A 4K0KE 2PNLA 3F0NA 2O3ZA 4DR2E 2F4VI 3LPSA 3J7AG 2JEBA 5DROA 1Z0VA 2JEAA 5JEAB 2DEIA 1N32E 1XNQE 1NHJA 4DPUA 1MU5A 4HXZA 5FLXQ 3T1HI 3HULA 1S16A 1Y4UA 1NHHA 1BKNA 2WNRB 1UDNA 5FLXC 1RREA 4DR3I 1Y4SA 3P3EA 2JE6A 3OTOE 2PNZB 4LF7I 3CWVA 4DR5E 4DUZI 4P7AA 4DV1I 4MU3A 4OX9I 4X64E 4U3DA 1B63A 4DU8A 2GQ0A 4XTJA 5BR8I 3L7ZA 4B3MI 4OO1A 4DV1E 3PYEA 1Y60A 4LF4I 1OYSA 4Z7YA 4I3HA 5C0XF 2O1UA 3M7ND 4NXNI 2ZM6I 1J5EI 2UUBI 4B3SI 4BA2A 4GKJI 4GKKI 5IT9Q 3QT5A 2IESA 1R6LA 4MDTA 1QZRA 1UDSA 5IT9C 2HHHI 1D6TA 2AJ4A 4OKGA 1FJGE 4DR7I 2UXDI 1IBME 3QT8A 4ISAA 2JE6B 3J80Q 4JYAI 1HNXI 4DV5I 1N34I 4DR6E 3ZZTA 3ZZUA 1KTVA 3J80C 2NN6C 4MYTA 5DNXA 5DNLA 4IFDB 4X65E 4IZKB 5L3JA 3J81C 3B8HA 1XMQE 1HNZE 4LF8I 4OO1B 2JT2A 4KHPI 4DR1I 2BM1A 1EA6A 4DUYI 3M85D 1PVGA 2ZITA 2PNMA 1Y6ZA 5GMDA 2C39B 5JEAA 2Z5EA 4FWDA 2PO1A 1WUUA 2BM0A 2AE8A 1ZM9A 1FI4A 1USUA 3H4LA 1N0UA 5C0XA 4NXME 4BA2B 4RPFA 4JI0I 4JI6E 2WNRA 5K36C 3WU5A 2VQEI 5JEAD 4LFAE 1EI1A 4LFBE 4JV5E 1H73A 4FW6A 1Z0EA 2PNZA 4LF6I 2Q2EB 4DV4E 5EKWA 2J7KA 4DXLA 5LMUI 1YHCA 1KVKA 3B78A 2GS8A 3V5RA 2EFGA 3U1KA 4OO1E 4JI3I 1N33E 3P76A 4IS9A 2J65A 4JI8I 4USMA 1A6FA 4X62I 3ZM7A 4HYMA 4LCGA 1RR9A 2VQFE 4URLA 2O1TA 4DV2I 4JI1I 5IWAI 2DEJA 4MQYA 4JI7E 2CG9A 2PO1B 1Z0BA 1Z5AA 2BA0G 1Z0TA 3PS3A 4JI1E 2F4VE 5C0XB 1ZM4A 3WU3A 2BR2B 4DPTA 3T1HE 4P52A 4DV6I 2NN6F 4JI4I 4MU1A 2IERA 4DV0I 3HJCA 3LNUA 4FW3A 4DR3E 4IFDA 4HACB 4DV0E 4JI5I 4IZKA 4LF7E 1Y5YA 4DUZE 2HKJA 1XMOI 1B62A 3K85A 4OX9E 4IFDD 1Z59A 3KRNA 5BR8E 4B3RI 2Z5CB 4EMDA 1ZXNA 2PO2A 4QNJA 2C38B 5JEAE 3P3GA 4B3ME 2C39A 5GMEA 4OO1D 1I94I 4LF4E 4FN5A 5C0XE 2C37A 5K36F 4DV7I 4NXNE 1MG7A 1Z0WA 2ZM6E 1J5EE 4DPWA 3Q6NA 2UUBE 4B3SE 1N0VC 4MYUA 2UXCI 2NPFA 2HK3A 4GKJE 4GKKE 2GO4A 4B3TI 2BV3A 4BA1B 1IBKI 4YY3I 2HHHE 3P06A 2WW4A 4ZVIA 4IZJB 1P42A 1UEKA 1S4EA 5DRRA 4DR7E 3B82A 4J3DA 2UXDE 4LCFA 2V34A 4R1FA 5ELWA 3J81Q 4JYAE 4LOMA 1HNXE 4DV5E 2IOQA 1N34E 1XNRI 2OI2A 1HNWI 4MU4A 5LMNI 4YHHI 4LF5I 1DARA 2ZBKB 4DU7A 4DR4I 3H1CA 3GCMA 2HKEA 1UDOA 2E5LI 1VI7A 1HNWE 3J7AM 2PO2B 4LF8E 3GONA 4DR1E 4KHPE 2X7IA 4MU0A 2A2CA 4DUYE 2C37B 1H74A 2R3VA 2UXBI 1UDQA 3PRYA 3CDJA 5FWKA 5EL9A 4DV3I 2CVEA 2BR2A 2UUCI 3Q6MA 1MX0A 5DRQA 4WUCA 4X66I 2UU9I 5K36A 4JI0E 3PS1A 1Z0CA 2PO0B 5C0XD 2VQEE 5DRPA 3B4TA 4IFDE 1PIEA 4AQYI 4HACA 4LF9I 5K36D 4DPYA 4LF6E 3ZZ0A 1ELOA 4LFCI 1FWLA 1HR0I 5LMUE 2LJPA 2BA1G 3ZKBA 2NN6B 1FKAE 2Z5CA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4LCG A;  2IER A;  3P3C A;  4FW3 A;  5DRQ A;  2IES A;  2O3Z A;  4FW6 A;  4MDT A;  3PS1 A;  4U3D A;  3U1Y A;  2JT2 A;  5DRO A;  5DRP A;  3NZK A;  4MQY A;  2VES A;  4OKG A;  1YHC A;  2GO4 A;  3UHM A;  3PS3 A;  4ISA A;  2GO3 A;  4FW7 A;  4FW4 A;  4OZE A;  1P42 A;  1YH8 A;  3P3G A;  1XXE A;  3P76 A;  4IS9 A;  4LCH A;  3P3E A;  5DRR A;  4FW5 A;  4J3D A;  2J65 A;  4LCF A;  4U3B A;  3PS2 A; 
#chains in the Genus database with same CATH topology
 3HKM A;  2C38 A;  4AM3 A;  4JI3 E;  2A2D A;  1NZ0 A;  4JI8 E;  3DD6 A;  1N36 I;  1RHY A;  1H7U A;  4X62 E;  3T1Y I;  2VES A;  3D4J A;  2UUA I;  3UHM A;  4JI2 I;  4DV2 E;  3V2U C;  5IWA E;  3Q1Q A;  4PU9 A;  1H7S A;  1VIS A;  4DPX A;  4AID A;  1FNM A;  2V2Q A;  4K0K I;  4FW5 A;  4BA1 A;  4DR2 I;  2BA0 D;  4PRX A;  4IZJ A;  5K36 B;  4WUB A;  1ZM2 A;  1N32 I;  1ZM3 A;  1XNQ I;  4USK A;  3M6A A;  1E3P A;  4FW9 A;  1PKP A;  4KQV A;  3JAM Q;  1KIJ A;  3PYF A;  4DV6 E;  2NN6 E;  4IZJ D;  3K1J A;  1E3H A;  4JI4 E;  3JAM C;  3PYD A;  4N3O A;  2O1W A;  3WU6 A;  3OTO I;  2WP8 B;  1ZXM A;  4FWH A;  4JI5 E;  3WU4 A;  4LPF A;  4UTG A;  4DR5 I;  3GME A;  4PRV A;  4X64 I;  4IFD C;  1XMO E;  3CDI A;  4B3R E;  3P3C A;  4OO1 C;  4WUD A;  1I94 E;  3M7N G;  2F1D A;  2V8P A;  5K36 E;  5JEA F;  4DV7 E;  2IOP A;  2PO0 A;  2Z5B B;  2UXC E;  3LTO A;  2R42 A;  1XHK A;  5A2Q Q;  4GQU A;  4B3T E;  2HFU A;  2E1R A;  5A2Q C;  1IBK E;  4U3B A;  2JEB B;  4YY3 E;  3PS2 A;  2JEA B;  2HFS A;  4M1K A;  4ED4 A;  1FJG I;  2V2V A;  2NN6 A;  1IBM I;  1U2R A;  3K17 A;  4FWG A;  4AIM A;  1USV A;  1H72 C;  4DR6 I;  1OYR A;  2X36 A;  1XNR E;  2NN6 D;  5LMN E;  4YHH E;  4LF5 E;  2GO3 A;  4DR4 E;  4OZE A;  1YH8 A;  4X65 I;  4QNK A;  2E5L E;  1XMQ I;  1OJ4 A;  1HNZ I;  2CZ9 A;  3ZKD A;  4Z7C A;  3M85 G;  1HK7 A;  2VF3 A;  2O1V A;  4HY1 A;  1IBL I;  3L7Z B;  5LL6 R;  2CGE A;  2UXB E;  3U1Y A;  4UT4 A;  1Z0G A;  5JEA C;  4DV3 E;  1IBL E;  3GLL A;  2XEX A;  2UUC E;  4NXM I;  2UU9 E;  4X66 E;  5C0X C;  4JI6 I;  1OYP A;  4LFA I;  4FW7 A;  4JG4 A;  4LFB I;  4JV5 I;  4AQY E;  4LF9 E;  2WP8 A;  3QT7 A;  1R6M A;  4NBQ A;  4IFD F;  4DV4 I;  4LFC E;  1HR0 E;  3PYG A;  4OO1 F;  2BA1 D;  3NZK A;  1K47 A;  1FWK A;  1N33 I;  1NHI A;  1Z5B A;  1N36 E;  3T1Y E;  2V2Z A;  4FW4 A;  1Z5C A;  2VQF I;  1XXE A;  2UUA E;  4LCH A;  2HK2 A;  1KKH A;  2Z5B A;  4JI2 E;  4JI7 I;  3QT6 A;  4K0K E;  2PNL A;  3F0N A;  2O3Z A;  4DR2 E;  2F4V I;  3LPS A;  3J7A G;  2JEB A;  5DRO A;  1Z0V A;  2JEA A;  5JEA B;  2DEI A;  1N32 E;  1XNQ E;  1NHJ A;  4DPU A;  1MU5 A;  4HXZ A;  5FLX Q;  3T1H I;  3HUL A;  1S16 A;  1Y4U A;  1NHH A;  1BKN A;  2WNR B;  1UDN A;  5FLX C;  1RRE A;  4DR3 I;  1Y4S A;  3P3E A;  2JE6 A;  3OTO E;  2PNZ B;  4LF7 I;  3CWV A;  4DR5 E;  4DUZ I;  4P7A A;  4DV1 I;  4MU3 A;  4OX9 I;  4X64 E;  4U3D A;  1B63 A;  4DU8 A;  2GQ0 A;  4XTJ A;  5BR8 I;  3L7Z A;  4B3M I;  4OO1 A;  4DV1 E;  3PYE A;  1Y60 A;  4LF4 I;  1OYS A;  4Z7Y A;  4I3H A;  5C0X F;  2O1U A;  3M7N D;  4NXN I;  2ZM6 I;  1J5E I;  2UUB I;  4B3S I;  4BA2 A;  4GKJ I;  4GKK I;  5IT9 Q;  3QT5 A;  2IES A;  1R6L A;  4MDT A;  1QZR A;  1UDS A;  5IT9 C;  2HHH I;  1D6T A;  2AJ4 A;  4OKG A;  1FJG E;  4DR7 I;  2UXD I;  1IBM E;  3QT8 A;  4ISA A;  2JE6 B;  3J80 Q;  4JYA I;  1HNX I;  4DV5 I;  1N34 I;  4DR6 E;  3ZZT A;  3ZZU A;  1KTV A;  3J80 C;  2NN6 C;  4MYT A;  5DNX A;  5DNL A;  4IFD B;  4X65 E;  4IZK B;  5L3J A;  3J81 C;  3B8H A;  1XMQ E;  1HNZ E;  4LF8 I;  4OO1 B;  2JT2 A;  4KHP I;  4DR1 I;  2BM1 A;  1EA6 A;  4DUY I;  3M85 D;  1PVG A;  2ZIT A;  2PNM A;  1Y6Z A;  5GMD A;  2C39 B;  5JEA A;  2Z5E A;  4FWD A;  2PO1 A;  1WUU A;  2BM0 A;  2AE8 A;  1ZM9 A;  1FI4 A;  1USU A;  3H4L A;  1N0U A;  5C0X A;  4NXM E;  4BA2 B;  4RPF A;  4JI0 I;  4JI6 E;  2WNR A;  5K36 C;  3WU5 A;  2VQE I;  5JEA D;  4LFA E;  1EI1 A;  4LFB E;  4JV5 E;  1H73 A;  4FW6 A;  1Z0E A;  2PNZ A;  4LF6 I;  2Q2E B;  4DV4 E;  5EKW A;  2J7K A;  4DXL A;  5LMU I;  1YHC A;  1KVK A;  3B78 A;  2GS8 A;  3V5R A;  2EFG A;  3U1K A;  4OO1 E;  4JI3 I;  1N33 E;  3P76 A;  4IS9 A;  2J65 A;  4JI8 I;  4USM A;  1A6F A;  4X62 I;  3ZM7 A;  4HYM A;  4LCG A;  1RR9 A;  2VQF E;  4URL A;  2O1T A;  4DV2 I;  4JI1 I;  5IWA I;  2DEJ A;  4MQY A;  4JI7 E;  2CG9 A;  2PO1 B;  1Z0B A;  1Z5A A;  2BA0 G;  1Z0T A;  3PS3 A;  4JI1 E;  2F4V E;  5C0X B;  1ZM4 A;  3WU3 A;  2BR2 B;  4DPT A;  3T1H E;  4P52 A;  4DV6 I;  2NN6 F;  4JI4 I;  4MU1 A;  2IER A;  4DV0 I;  3HJC A;  3LNU A;  4FW3 A;  4DR3 E;  4IFD A;  4HAC B;  4DV0 E;  4JI5 I;  4IZK A;  4LF7 E;  1Y5Y A;  4DUZ E;  2HKJ A;  1XMO I;  1B62 A;  3K85 A;  4OX9 E;  4IFD D;  1Z59 A;  3KRN A;  5BR8 E;  4B3R I;  2Z5C B;  4EMD A;  1ZXN A;  2PO2 A;  4QNJ A;  2C38 B;  5JEA E;  3P3G A;  4B3M E;  2C39 A;  5GME A;  4OO1 D;  1I94 I;  4LF4 E;  4FN5 A;  5C0X E;  2C37 A;  5K36 F;  4DV7 I;  4NXN E;  1MG7 A;  1Z0W A;  2ZM6 E;  1J5E E;  4DPW A;  3Q6N A;  2UUB E;  4B3S E;  1N0V C;  4MYU A;  2UXC I;  2NPF A;  2HK3 A;  4GKJ E;  4GKK E;  2GO4 A;  4B3T I;  2BV3 A;  4BA1 B;  1IBK I;  4YY3 I;  2HHH E;  3P06 A;  2WW4 A;  4ZVI A;  4IZJ B;  1P42 A;  1UEK A;  1S4E A;  5DRR A;  4DR7 E;  3B82 A;  4J3D A;  2UXD E;  4LCF A;  2V34 A;  4R1F A;  5ELW A;  3J81 Q;  4JYA E;  4LOM A;  1HNX E;  4DV5 E;  2IOQ A;  1N34 E;  1XNR I;  2OI2 A;  1HNW I;  4MU4 A;  5LMN I;  4YHH I;  4LF5 I;  1DAR A;  2ZBK B;  4DU7 A;  4DR4 I;  3H1C A;  3GCM A;  2HKE A;  1UDO A;  2E5L I;  1VI7 A;  1HNW E;  3J7A M;  2PO2 B;  4LF8 E;  3GON A;  4DR1 E;  4KHP E;  2X7I A;  4MU0 A;  2A2C A;  4DUY E;  2C37 B;  1H74 A;  2R3V A;  2UXB I;  1UDQ A;  3PRY A;  3CDJ A;  5FWK A;  5EL9 A;  4DV3 I;  2CVE A;  2BR2 A;  2UUC I;  3Q6M A;  1MX0 A;  5DRQ A;  4WUC A;  4X66 I;  2UU9 I;  5K36 A;  4JI0 E;  3PS1 A;  1Z0C A;  2PO0 B;  5C0X D;  2VQE E;  5DRP A;  3B4T A;  4IFD E;  1PIE A;  4AQY I;  4HAC A;  4LF9 I;  5K36 D;  4DPY A;  4LF6 E;  3ZZ0 A;  1ELO A;  4LFC I;  1FWL A;  1HR0 I;  5LMU E;  2LJP A;  2BA1 G;  3ZKB A;  2NN6 B;  1FKA E;  2Z5C A; 
#chains in the Genus database with same CATH homology
 4LCG A;  2IER A;  3P3C A;  4FW3 A;  5DRQ A;  2IES A;  2O3Z A;  4FW6 A;  4MDT A;  3PS1 A;  4U3D A;  3U1Y A;  2JT2 A;  5DRO A;  5DRP A;  3NZK A;  4MQY A;  2VES A;  4OKG A;  1YHC A;  2GO4 A;  3UHM A;  3PS3 A;  4ISA A;  2GO3 A;  4FW7 A;  4FW4 A;  4OZE A;  1P42 A;  1YH8 A;  3P3G A;  1XXE A;  3P76 A;  4IS9 A;  4LCH A;  3P3E A;  5DRR A;  4FW5 A;  4J3D A;  2J65 A;  4LCF A;  4U3B A;  3PS2 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4FW6A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations