4FW6A

Crystal structure of the lpxc in complex with n-[(2s,3r)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(phenylethynyl)benzamide inhibitor
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
300
structure length
300
Chain Sequence
AMIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the LpxC
rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Pseudomonas aeruginosa
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 88
structure length 300
sequence length 300
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2012-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4fw6A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4fw6A02
3P3CA 4MDTA 1YHCA 2VESA 4FW3A 4FW7A 3NZKA 1YH8A 2GO3A 5DRPA 2IESA 1XXEA 5DROA 4U3DA 2IERA 4U3BA 4IS9A 4OZEA 3P3EA 4LCFA 3UHMA 2JT2A 3U1YA 3PS2A 2GO4A 2O3ZA 4LCHA 3PS3A 4LCGA 5DRRA 4ISAA 3P3GA 4FW4A 1P42A 2J65A 4FW5A 3PS1A 4FW6A 4J3DA 4MQYA 5DRQA 3P76A 4OKGA
chains in the Genus database with same CATH superfamily
5L3JA 4AQYE 4LF9E 4OO1E 4JI5I 4MDTA 2WW4A 2PO0B 2UUCI 1VI7A 2DEJA 5DRPA 4IFDA 1FWLA 4QNKA 4WUDA 3J81Q 2ZM6E 5DNLA 4DR1I 1FKAE 2UU9E 3PYGA 1Z0GA 2GO4A 4DV4E 4OO1D 4LCGA 1Y6ZA 4DV6E 2JEAB 4DPXA 3B4TA 5DRQA 4DUZE 4IFDF 1ELOA 2C39B 4M1KA 3M6AA 1Y5YA 2V2QA 4JI1I 5A2QC 2BM0A 1HNZI 5DNXA 4DPTA 1RREA 4JI0E 1FJGE 4MYUA 4UTGA 4URLA 4DV0I 4DR4I 2Z5CB 1Y4SA 2IESA 4DR5I 1ZXMA 2NN6A 2HHHE 2PO1B 1UDSA 4NXNI 1S16A 2UXBI 5IWAE 1B62A 3LNUA 1IBKE 2OI2A 2X7IA 5IT9C 1Z0WA 4IZJB 4FN5A 1FNMA 2NN6F 4FWDA 4PRVA 2VQFI 3J80C 1Z5BA 2BA1G 4KQVA 1XMOE 4B3SE 1Z5AA 2E1RA 3GMEA 2HKJA 1N34I 2HK3A 5C0XC 4LF7E 2F4VI 4JV5I 3HJCA 4BA1A 4YHHE 3WU3A 1XNQE 2BM1A 4DV3I 5DRRA 2VQEI 1Z0TA 4OO1C 5JEAB 1Z59A 2AE8A 4DV2E 4DUYE 5BR8I 3QT8A 4LFAE 5FLXC 2NPFA 4JYAE 3T1HE 2BA1D 4U3DA 4B3TE 2XEXA 4IZKB 3P3EA 5LMUI 1UDOA 2WNRB 4X65I 1ZXNA 5JEAF 3PS2A 1I94I 4OX9I 1N32E 3LPSA 1OJ4A 2O1VA 2V34A 4X64E 2BR2A 4DPWA 1N36I 4KHPI 3ZKDA 3J7AM 4DV5E 4HACB 4JI3I 4NXMI 2O1TA 2UUBE 1USVA 3M85D 2CVEA 3HULA 1Z0VA 3PS3A 2Q2EB 3OTOE 1XNRI 4LPFA 4DR3E 4LFBI 3GLLA 3PYFA 1HNXI 2V8PA 3V2UC 2J7KA 3CDIA 4JI5E 3P3CA 1WUUA 1ZM3A 1HNWE 4IFDE 2UXCI 4FW3A 2UUCE 4PRXA 2PO0A 3QT6A 1XMQI 1YH8A 4K0KI 1ZM2A 5K36B 1Z5CA 4EMDA 2Z5BB 5IT9Q 2BA0G 5C0XB 4MU4A 4IFDD 2JEAA 4JI8I 4MYTA 3J80Q 4JI1E 1HNZE 3K1JA 1KKHA 2C39A 4LF9I 3LTOA 5K36F 4OO1B 4DV0E 4DR4E 2NN6E 4B3RI 2HKEA 4WUBA 4DR5E 2GO3A 2IOQA 2Z5CA 5DROA 4R1FA 3L7ZB 1H73A 4QNJA 4NXNE 4OZEA 4DR6I 4DV7I 2PO1A 4BA2B 1J5EI 1IBLI 4XTJA 4B3MI 2NN6D 2BA0D 3M7NG 4GKJI 2PO2B 4IZJA 4ZVIA 3K17A 1FI4A 2HK2A 4FWGA 4GQUA 2CZ9A 4DR7I 5LMNE 1U2RA 4X62I 4LF4I 1E3PA 4IZJD 1ZM9A 1FWKA 2F4VE 1KVKA 4P7AA 3J81C 3DD6A 4LCHA 1NHHA 5IWAI 1VISA 4JI4I 5EKWA 4HYMA 4DV3E 3U1KA 4LFCE 2VQEE 3JAMQ 5JEAE 2IOPA 4FW4A 1N33I 4J3DA 4MQYA 2HFUA 4MU0A 4UT4A 4LF5I 5EL9A 4YY3I 2UUAE 4IFDC 5LL6R 5BR8E 5JEAA 3T1YI 1MG7A 4JI2I 2VESA 5GMEA 1HK7A 2UXDI 4DPYA 1EI1A 5FWKA 3QT7A 1KTVA 4IS9A 5JEAD 5LMUE 4LF6I 4X65E 4IZKA 1I94E 2V2VA 2WNRA 3H4LA 4FWHA 4JI7I 2PNZB 4Z7YA 2Z5EA 2C38B 3ZKBA 2E5LI 4FW6A 1PIEA 4X66E 1KIJA 3B78A 3ZZ0A 4DV2I 4DR2I 4DUYI 1N36E 2NN6C 1NZ0A 5ELWA 4N3OA 4DV1I 2R3VA 4AIDA 4KHPE 1B63A 2IERA 4USKA 1XHKA 4MU1A 4JI3E 1BKNA 2WP8B 4NXME 1IBMI 4PU9A 4LF8I 1D6TA 4WUCA 4HACA 1Y60A 1Z0BA 1XNRE 3CWVA 1R6MA 2C37B 2AJ4A 4LFBE 1HNXE 1QZRA 5A2QQ 1P42A 4DU7A 4JI6I 4FW9A 2UXBE 1DARA 3WU4A 1RR9A 4I3HA 4X64I 2UXCE 1Y4UA 2HFSA 1HR0I 2JEBB 1PVGA 4AIMA 3NZKA 1XMQE 4K0KE 4NBQA 5K36E 2JE6B 4USMA 1N0VC 4DR1E 4ED4A 3PRYA 5K36A 1S4EA 4AM3A 2Z5BA 3ZM7A 5JEAC 2R42A 1A6FA 4DR3I 4GKKI 4ISAA 4P52A 5C0XA 1MX0A 3H1CA 4JI8E 2CGEA 4FW5A 5K36D 3GONA 3P06A 1XMOI 1MU5A 4AQYI 2BV3A 1HNWI 1YHCA 4B3RE 1OYPA 3WU6A 5C0XD 1R6LA 1USUA 4OO1A 4LOMA 4IFDB 1H7SA 4DXLA 3ZZUA 4DU8A 5C0XF 4DV7E 4DR6E 2ZM6I 3B82A 1H7UA 3L7ZA 1J5EE 1IBLE 3U1YA 1H74A 2GQ0A 1RHYA 3V5RA 2UU9I 2F1DA 4B3ME 4BA2A 3HKMA 4DV4I 2EFGA 4DV6I 4OO1F 4GKJE 4MU3A 4DUZI 5FLXQ 1UEKA 2PO2A 3GCMA 2PNLA 2VQFE 4DR7E 3D4JA 4X62E 4LF4E 4JI0I 1FJGI 2ZITA 2NN6B 4HY1A 2HHHI 1OYRA 1N34E 3UHMA 3PYEA 4JV5E 2PNMA 1UDQA 2VF3A 4JI4E 1NHIA 2GS8A 1IBKI 1K47A 1N33E 4LF5E 2J65A 4YY3E 3T1YE 3M7ND 4JI2E 4Z7CA 5K36C 4FW7A 5LMNI 1EA6A 2O1UA 2UXDE 4LF6E 4B3SI 5GMDA 4BA1B 2JT2A 2CG9A 2A2DA 4LF7I 4YHHI 2O1WA 4OX9E 1XNQI 4JI7E 1H72C 4LFCI 3CDJA 1N0UA 2DEIA 2E5LE 3ZZTA 2PNZA 2C38A 4HXZA 3Q1QA 3WU5A 4OKGA 4DR2E 2UUAI 2A2CA 2X36A 4DV1E 4LFAI 4JYAI 1XXEA 4U3BA 3T1HI 1UDNA 3M85G 1IBME 4RPFA 4LF8E 2LJPA 4B3TI 4LCFA 1OYSA 2WP8A 1Z0EA 3Q6NA 1ZM4A 3F0NA 2C37A 4JI6E 3J7AG 4X66I 1N32I 1NHJA 3JAMC 2BR2B 4JG4A 4DPUA 1HR0E 2JEBA 2ZBKB 3QT5A 1PKPA 2JE6A 2V2ZA 4DV5I 1Z0CA 3K85A 3B8HA 5C0XE 2O3ZA 3PYDA 3Q6MA 2UUBI 4GKKE 3KRNA 3OTOI 3P3GA 3PS1A 1E3HA 3P76A
chains in the Genus database with same CATH topology
3P3CA 4MDTA 1YHCA 2VESA 4FW3A 4FW7A 3NZKA 1YH8A 2GO3A 5DRPA 2IESA 1XXEA 5DROA 4U3DA 2IERA 4U3BA 4IS9A 4OZEA 3P3EA 4LCFA 3UHMA 2JT2A 3U1YA 3PS2A 2GO4A 2O3ZA 4LCHA 3PS3A 4LCGA 5DRRA 4ISAA 3P3GA 4FW4A 1P42A 2J65A 4FW5A 3PS1A 4FW6A 4J3DA 4MQYA 5DRQA 3P76A 4OKGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P3C A;  4MDT A;  1YHC A;  2VES A;  4FW3 A;  4FW7 A;  3NZK A;  1YH8 A;  2GO3 A;  5DRP A;  2IES A;  1XXE A;  5DRO A;  4U3D A;  2IER A;  4U3B A;  4IS9 A;  4OZE A;  3P3E A;  4LCF A;  3UHM A;  2JT2 A;  3U1Y A;  3PS2 A;  2GO4 A;  2O3Z A;  4LCH A;  3PS3 A;  4LCG A;  5DRR A;  4ISA A;  3P3G A;  4FW4 A;  1P42 A;  2J65 A;  4FW5 A;  3PS1 A;  4FW6 A;  4J3D A;  4MQY A;  5DRQ A;  3P76 A;  4OKG A; 
#chains in the Genus database with same CATH topology
 5L3J A;  4AQY E;  4LF9 E;  4OO1 E;  4JI5 I;  4MDT A;  2WW4 A;  2PO0 B;  2UUC I;  1VI7 A;  2DEJ A;  5DRP A;  4IFD A;  1FWL A;  4QNK A;  4WUD A;  3J81 Q;  2ZM6 E;  5DNL A;  4DR1 I;  1FKA E;  2UU9 E;  3PYG A;  1Z0G A;  2GO4 A;  4DV4 E;  4OO1 D;  4LCG A;  1Y6Z A;  4DV6 E;  2JEA B;  4DPX A;  3B4T A;  5DRQ A;  4DUZ E;  4IFD F;  1ELO A;  2C39 B;  4M1K A;  3M6A A;  1Y5Y A;  2V2Q A;  4JI1 I;  5A2Q C;  2BM0 A;  1HNZ I;  5DNX A;  4DPT A;  1RRE A;  4JI0 E;  1FJG E;  4MYU A;  4UTG A;  4URL A;  4DV0 I;  4DR4 I;  2Z5C B;  1Y4S A;  2IES A;  4DR5 I;  1ZXM A;  2NN6 A;  2HHH E;  2PO1 B;  1UDS A;  4NXN I;  1S16 A;  2UXB I;  5IWA E;  1B62 A;  3LNU A;  1IBK E;  2OI2 A;  2X7I A;  5IT9 C;  1Z0W A;  4IZJ B;  4FN5 A;  1FNM A;  2NN6 F;  4FWD A;  4PRV A;  2VQF I;  3J80 C;  1Z5B A;  2BA1 G;  4KQV A;  1XMO E;  4B3S E;  1Z5A A;  2E1R A;  3GME A;  2HKJ A;  1N34 I;  2HK3 A;  5C0X C;  4LF7 E;  2F4V I;  4JV5 I;  3HJC A;  4BA1 A;  4YHH E;  3WU3 A;  1XNQ E;  2BM1 A;  4DV3 I;  5DRR A;  2VQE I;  1Z0T A;  4OO1 C;  5JEA B;  1Z59 A;  2AE8 A;  4DV2 E;  4DUY E;  5BR8 I;  3QT8 A;  4LFA E;  5FLX C;  2NPF A;  4JYA E;  3T1H E;  2BA1 D;  4U3D A;  4B3T E;  2XEX A;  4IZK B;  3P3E A;  5LMU I;  1UDO A;  2WNR B;  4X65 I;  1ZXN A;  5JEA F;  3PS2 A;  1I94 I;  4OX9 I;  1N32 E;  3LPS A;  1OJ4 A;  2O1V A;  2V34 A;  4X64 E;  2BR2 A;  4DPW A;  1N36 I;  4KHP I;  3ZKD A;  3J7A M;  4DV5 E;  4HAC B;  4JI3 I;  4NXM I;  2O1T A;  2UUB E;  1USV A;  3M85 D;  2CVE A;  3HUL A;  1Z0V A;  3PS3 A;  2Q2E B;  3OTO E;  1XNR I;  4LPF A;  4DR3 E;  4LFB I;  3GLL A;  3PYF A;  1HNX I;  2V8P A;  3V2U C;  2J7K A;  3CDI A;  4JI5 E;  3P3C A;  1WUU A;  1ZM3 A;  1HNW E;  4IFD E;  2UXC I;  4FW3 A;  2UUC E;  4PRX A;  2PO0 A;  3QT6 A;  1XMQ I;  1YH8 A;  4K0K I;  1ZM2 A;  5K36 B;  1Z5C A;  4EMD A;  2Z5B B;  5IT9 Q;  2BA0 G;  5C0X B;  4MU4 A;  4IFD D;  2JEA A;  4JI8 I;  4MYT A;  3J80 Q;  4JI1 E;  1HNZ E;  3K1J A;  1KKH A;  2C39 A;  4LF9 I;  3LTO A;  5K36 F;  4OO1 B;  4DV0 E;  4DR4 E;  2NN6 E;  4B3R I;  2HKE A;  4WUB A;  4DR5 E;  2GO3 A;  2IOQ A;  2Z5C A;  5DRO A;  4R1F A;  3L7Z B;  1H73 A;  4QNJ A;  4NXN E;  4OZE A;  4DR6 I;  4DV7 I;  2PO1 A;  4BA2 B;  1J5E I;  1IBL I;  4XTJ A;  4B3M I;  2NN6 D;  2BA0 D;  3M7N G;  4GKJ I;  2PO2 B;  4IZJ A;  4ZVI A;  3K17 A;  1FI4 A;  2HK2 A;  4FWG A;  4GQU A;  2CZ9 A;  4DR7 I;  5LMN E;  1U2R A;  4X62 I;  4LF4 I;  1E3P A;  4IZJ D;  1ZM9 A;  1FWK A;  2F4V E;  1KVK A;  4P7A A;  3J81 C;  3DD6 A;  4LCH A;  1NHH A;  5IWA I;  1VIS A;  4JI4 I;  5EKW A;  4HYM A;  4DV3 E;  3U1K A;  4LFC E;  2VQE E;  3JAM Q;  5JEA E;  2IOP A;  4FW4 A;  1N33 I;  4J3D A;  4MQY A;  2HFU A;  4MU0 A;  4UT4 A;  4LF5 I;  5EL9 A;  4YY3 I;  2UUA E;  4IFD C;  5LL6 R;  5BR8 E;  5JEA A;  3T1Y I;  1MG7 A;  4JI2 I;  2VES A;  5GME A;  1HK7 A;  2UXD I;  4DPY A;  1EI1 A;  5FWK A;  3QT7 A;  1KTV A;  4IS9 A;  5JEA D;  5LMU E;  4LF6 I;  4X65 E;  4IZK A;  1I94 E;  2V2V A;  2WNR A;  3H4L A;  4FWH A;  4JI7 I;  2PNZ B;  4Z7Y A;  2Z5E A;  2C38 B;  3ZKB A;  2E5L I;  4FW6 A;  1PIE A;  4X66 E;  1KIJ A;  3B78 A;  3ZZ0 A;  4DV2 I;  4DR2 I;  4DUY I;  1N36 E;  2NN6 C;  1NZ0 A;  5ELW A;  4N3O A;  4DV1 I;  2R3V A;  4AID A;  4KHP E;  1B63 A;  2IER A;  4USK A;  1XHK A;  4MU1 A;  4JI3 E;  1BKN A;  2WP8 B;  4NXM E;  1IBM I;  4PU9 A;  4LF8 I;  1D6T A;  4WUC A;  4HAC A;  1Y60 A;  1Z0B A;  1XNR E;  3CWV A;  1R6M A;  2C37 B;  2AJ4 A;  4LFB E;  1HNX E;  1QZR A;  5A2Q Q;  1P42 A;  4DU7 A;  4JI6 I;  4FW9 A;  2UXB E;  1DAR A;  3WU4 A;  1RR9 A;  4I3H A;  4X64 I;  2UXC E;  1Y4U A;  2HFS A;  1HR0 I;  2JEB B;  1PVG A;  4AIM A;  3NZK A;  1XMQ E;  4K0K E;  4NBQ A;  5K36 E;  2JE6 B;  4USM A;  1N0V C;  4DR1 E;  4ED4 A;  3PRY A;  5K36 A;  1S4E A;  4AM3 A;  2Z5B A;  3ZM7 A;  5JEA C;  2R42 A;  1A6F A;  4DR3 I;  4GKK I;  4ISA A;  4P52 A;  5C0X A;  1MX0 A;  3H1C A;  4JI8 E;  2CGE A;  4FW5 A;  5K36 D;  3GON A;  3P06 A;  1XMO I;  1MU5 A;  4AQY I;  2BV3 A;  1HNW I;  1YHC A;  4B3R E;  1OYP A;  3WU6 A;  5C0X D;  1R6L A;  1USU A;  4OO1 A;  4LOM A;  4IFD B;  1H7S A;  4DXL A;  3ZZU A;  4DU8 A;  5C0X F;  4DV7 E;  4DR6 E;  2ZM6 I;  3B82 A;  1H7U A;  3L7Z A;  1J5E E;  1IBL E;  3U1Y A;  1H74 A;  2GQ0 A;  1RHY A;  3V5R A;  2UU9 I;  2F1D A;  4B3M E;  4BA2 A;  3HKM A;  4DV4 I;  2EFG A;  4DV6 I;  4OO1 F;  4GKJ E;  4MU3 A;  4DUZ I;  5FLX Q;  1UEK A;  2PO2 A;  3GCM A;  2PNL A;  2VQF E;  4DR7 E;  3D4J A;  4X62 E;  4LF4 E;  4JI0 I;  1FJG I;  2ZIT A;  2NN6 B;  4HY1 A;  2HHH I;  1OYR A;  1N34 E;  3UHM A;  3PYE A;  4JV5 E;  2PNM A;  1UDQ A;  2VF3 A;  4JI4 E;  1NHI A;  2GS8 A;  1IBK I;  1K47 A;  1N33 E;  4LF5 E;  2J65 A;  4YY3 E;  3T1Y E;  3M7N D;  4JI2 E;  4Z7C A;  5K36 C;  4FW7 A;  5LMN I;  1EA6 A;  2O1U A;  2UXD E;  4LF6 E;  4B3S I;  5GMD A;  4BA1 B;  2JT2 A;  2CG9 A;  2A2D A;  4LF7 I;  4YHH I;  2O1W A;  4OX9 E;  1XNQ I;  4JI7 E;  1H72 C;  4LFC I;  3CDJ A;  1N0U A;  2DEI A;  2E5L E;  3ZZT A;  2PNZ A;  2C38 A;  4HXZ A;  3Q1Q A;  3WU5 A;  4OKG A;  4DR2 E;  2UUA I;  2A2C A;  2X36 A;  4DV1 E;  4LFA I;  4JYA I;  1XXE A;  4U3B A;  3T1H I;  1UDN A;  3M85 G;  1IBM E;  4RPF A;  4LF8 E;  2LJP A;  4B3T I;  4LCF A;  1OYS A;  2WP8 A;  1Z0E A;  3Q6N A;  1ZM4 A;  3F0N A;  2C37 A;  4JI6 E;  3J7A G;  4X66 I;  1N32 I;  1NHJ A;  3JAM C;  2BR2 B;  4JG4 A;  4DPU A;  1HR0 E;  2JEB A;  2ZBK B;  3QT5 A;  1PKP A;  2JE6 A;  2V2Z A;  4DV5 I;  1Z0C A;  3K85 A;  3B8H A;  5C0X E;  2O3Z A;  3PYD A;  3Q6M A;  2UUB I;  4GKK E;  3KRN A;  3OTO I;  3P3G A;  3PS1 A;  1E3H A;  3P76 A; 
#chains in the Genus database with same CATH homology
 3P3C A;  4MDT A;  1YHC A;  2VES A;  4FW3 A;  4FW7 A;  3NZK A;  1YH8 A;  2GO3 A;  5DRP A;  2IES A;  1XXE A;  5DRO A;  4U3D A;  2IER A;  4U3B A;  4IS9 A;  4OZE A;  3P3E A;  4LCF A;  3UHM A;  2JT2 A;  3U1Y A;  3PS2 A;  2GO4 A;  2O3Z A;  4LCH A;  3PS3 A;  4LCG A;  5DRR A;  4ISA A;  3P3G A;  4FW4 A;  1P42 A;  2J65 A;  4FW5 A;  3PS1 A;  4FW6 A;  4J3D A;  4MQY A;  5DRQ A;  3P76 A;  4OKG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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