4LOMA

Crystal structure of mycobacterium tuberculosis hisb in complex with its substrate
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
191
structure length
191
Chain Sequence
SRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDPRV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
source organism Mycobacterium tuberculosis
publication title Crystal structures of the native, substrate- bound and inhibited forms of Mycobacterium tuberculosis imidazole glycerol phosphate dehydratase
rcsb
molecule keywords Imidazoleglycerol-phosphate dehydratase
total genus 57
structure length 191
sequence length 191
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2013-07-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4lomA01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4lomA02
2F1DA 2AE8A 5EKWA 4GQUA 4MU4A 4LPFA 1RHYA 5ELWA 4QNKA 4MU3A 4QNJA 4MU0A 4LOMA 5DNXA 5DNLA 5EL9A 4MU1A
chains in the Genus database with same CATH superfamily
5C0XE 4LF4I 3M85D 2UXCI 2BA0G 5BR8E 1FI4A 1XMOI 1OYSA 3F0NA 3GMEA 4DR2I 1HNXI 4DV4I 4XTJA 1RR9A 1Y4UA 1A6FA 4JI6I 4DR4I 3GONA 2ZM6E 1HR0E 2J7KA 4DR3E 1H7SA 3WU3A 4LF7E 4DPXA 4LCFA 2PO2A 4DR1I 2HK2A 1HNZI 1N32E 5K36B 2GO4A 1N34I 2J65A 2O1TA 2O1UA 3OTOE 1FJGE 4JI3E 1QZRA 4OO1D 1H7UA 4B3SI 4K0KI 1N36E 2C37A 1I94I 5EKWA 2X36A 4NXMI 3L7ZA 2IESA 4B3ME 5JEAD 3T1YE 5C0XB 4IFDC 1UDSA 4FWHA 2NN6A 4FWDA 2BR2B 4IFDA 2XEXA 2UXBI 4LOMA 4JI7I 1KVKA 4DV5I 4JI2E 4LF6E 4OO1E 4USKA 4LPFA 1ZM4A 3WU4A 4NBQA 4X64E 5JEAE 3J7AM 4QNKA 4LF9E 2NN6D 1XNQI 2JE6B 2UU9I 4HACB 4MU0A 3KRNA 4DV7I 3HKMA 4FW4A 4LFCE 2VESA 5A2QQ 1XMQI 4KQVA 1ZM9A 4PU9A 2IOPA 2NN6E 3OTOI 2PNMA 1VI7A 4DV0I 4DPWA 4LF8E 2BA1D 1J5EI 5K36C 4GKKE 2CG9A 5K36A 4I3HA 1MG7A 3T1HI 1USUA 4X65I 4DV1I 4LF4E 4X66E 2V2ZA 2Z5CA 2UXCE 4DPTA 5LMNI 1XMOE 2V8PA 5DROA 3V5RA 1XNRE 1Y5YA 4LCGA 1FWKA 2O1WA 1HNXE 5C0XC 4AQYI 4DV4E 2DEIA 2PO2B 4JYAE 4DUZI 4LF5I 4DR4E 1R6MA 4JI6E 4IZKA 3ZZUA 2C38A 1RREA 4J3DA 4DR1E 2R3VA 1FKAE 1HNZE 3M6AA 5GMDA 1UEKA 3L7ZB 1N34E 1ELOA 1N0UA 1RHYA 2NN6B 4B3SE 4K0KE 2HFSA 4MYUA 1I94E 4DV6I 4LCHA 4NXME 4NXNI 1IBMI 4DR6E 3B82A 4ZVIA 1H74A 2HKEA 3B78A 4P52A 4LFBI 1UDQA 2UXBE 2A2CA 1NHHA 4JI7E 4Z7CA 3NZKA 4X66I 4DV5E 1HNWI 1HK7A 4DV2I 1XNRI 4KHPI 3UHMA 5DRRA 3B8HA 1OJ4A 1Y6ZA 3J80Q 2AJ4A 3CDJA 4JYAI 1EA6A 4OO1C 3DD6A 1XNQE 4OO1A 4UT4A 3PYEA 1PIEA 4QNJA 2HK3A 4AIMA 2IERA 2UU9E 4DV7E 5FLXQ 2HKJA 1OYPA 5JEAC 3M7NG 2CZ9A 5JEAA 4MDTA 1NHJA 4DPYA 1B62A 1XMQE 1MX0A 3P76A 5LMUI 4JI4E 2PNLA 4FW7A 4IS9A 4WUDA 4DV0E 1KIJA 2Z5CB 4BA1A 1J5EE 2F4VI 4JI1E 4JV5I 5ELWA 1ZXNA 3P3EA 3T1HE 4DR6I 4X65E 4DV1E 2NN6C 2JEAA 4GQUA 5IT9Q 4MU3A 5LMNE 4HYMA 4JG4A 1Z59A 4YHHI 1N33I 4IZKB 1Z0BA 2C38B 4URLA 4DR7I 3J80C 2VQEI 2BV3A 4AQYE 4FW5A 4M1KA 1Z0GA 4MQYA 4P7AA 4FWGA 4DUZE 4LF5E 2X7IA 4X62I 4USMA 3M85G 2VF3A 1S16A 4MYTA 4YY3I 5FLXC 4B3TI 1PKPA 3HULA 3PRYA 2Z5BA 2WW4A 3PYDA 5DNXA 3V2UC 1ZXMA 2UUBI 4JI4I 1S4EA 2IOQA 3P3GA 4DV6E 2UUAE 2PO1A 4NXNE 1IBME 4JI1I 1UDNA 5IWAI 4IFDF 5IT9C 4LFBE 1H73A 1FWLA 4HY1A 3JAMQ 3QT8A 2BM0A 1HNWE 2GS8A 4DV2E 4OO1B 1UDOA 4KHPE 1Z5BA 3GLLA 3CWVA 4PRVA 4LFAI 5FWKA 5JEAB 3HJCA 2BA0D 3B4TA 3GCMA 3QT6A 3LNUA 2VQFI 4JI0E 4BA1B 5DRQA 5A2QC 3QT7A 5LMUE 5LL6R 4JI5I 2JEAB 2HFUA 4ED4A 4FW9A 3ZM7A 5K36F 3Q1QA 2F4VE 4JV5E 3LTOA 4IZJD 3WU5A 2UUAI 4AIDA 1KKHA 1IBKI 4MU4A 4FW6A 2C39B 2OI2A 3JAMC 3ZZ0A 4DV3I 4EMDA 4YHHE 1N33E 1WUUA 2BA1G 2A2DA 2Z5EA 4UTGA 4MU1A 5C0XD 4DR7E 5C0XF 3Q6NA 2JEBB 2VQEE 2GO3A 2WP8A 4JI8I 4Z7YA 4X62E 2E5LI 2Z5BB 3K1JA 3LPSA 3ZZTA 3ZKBA 3ZKDA 5DRPA 4YY3E 4B3TE 3U1KA 1Z0EA 2LJPA 1PVGA 1E3HA 1YHCA 4JI0I 3U1YA 2PO1B 3PYFA 5DNLA 1D6TA 1DARA 4OKGA 2UUBE 3K85A 2UUCI 5L3JA 2V34A 1Z5CA 1IBLE 4WUCA 4FN5A 1YH8A 5GMEA 5IWAE 2JT2A 1Z5AA 4BA2A 2BM1A 1B63A 2O1VA 4GKJI 2HHHI 1Z0TA 2F1DA 1U2RA 4N3OA 1USVA 2R42A 1OYRA 4IZJB 4DUYE 4DR5I 4B3RI 1R6LA 2C39A 4DPUA 4LFAE 4OO1F 3PS1A 1XXEA 2PO0A 1Y60A 2PNZA 4OX9E 4FW3A 2E1RA 2VQFE 2JEBA 4U3BA 3PYGA 5JEAF 2WNRA 1FNMA 4DU7A 1P42A 5BR8I 4JI5E 3H4LA 2O3ZA 4PRXA 3CDIA 1VISA 1NHIA 4ISAA 1Z0VA 1ZM2A 4DXLA 3PS3A 2ZBKB 1IBLI 1IBKE 5EL9A 3P3CA 2NN6F 3Q6MA 1NZ0A 2WP8B 4IFDD 1ZM3A 1BKNA 2ZM6I 1HR0I 4DV3E 4DR3I 4LF7I 3K17A 4DU8A 2UXDE 1N0VC 3H1CA 4WUBA 2CVEA 3D4JA 1N32I 2ZITA 4JI8E 4DUYI 2E5LE 1FJGI 4HXZA 1XHKA 4RPFA 4JI3I 4IFDE 1N36I 1K47A 3J81Q 4OX9I 4B3MI 4IZJA 2V2QA 2GQ0A 3T1YI 1MU5A 1Y4SA 2UUCE 4U3DA 4BA2B 4JI2I 4LF6I 1H72C 2DEJA 4DR2E 3J7AG 1Z0WA 5C0XA 5K36D 2BR2A 4X64I 3M7ND 1Z0CA 4LF9I 4AM3A 1EI1A 4GKJE 4OZEA 2HHHE 2CGEA 2C37B 3PS2A 3WU6A 2PO0B 2UXDI 2PNZB 2Q2EB 5K36E 4LFCI 1KTVA 3P06A 4DR5E 4B3RE 2WNRB 2JE6A 3QT5A 1E3PA 2NPFA 2EFGA 2V2VA 4IFDB 2AE8A 4HACA 3J81C 4LF8I 4R1FA 4GKKI
chains in the Genus database with same CATH topology
2F1DA 2AE8A 5EKWA 4GQUA 4MU4A 4LPFA 1RHYA 5ELWA 4QNKA 4MU3A 4QNJA 4MU0A 4LOMA 5DNXA 5DNLA 5EL9A 4MU1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F1D A;  2AE8 A;  5EKW A;  4GQU A;  4MU4 A;  4LPF A;  1RHY A;  5ELW A;  4QNK A;  4MU3 A;  4QNJ A;  4MU0 A;  4LOM A;  5DNX A;  5DNL A;  5EL9 A;  4MU1 A; 
#chains in the Genus database with same CATH topology
 5C0X E;  4LF4 I;  3M85 D;  2UXC I;  2BA0 G;  5BR8 E;  1FI4 A;  1XMO I;  1OYS A;  3F0N A;  3GME A;  4DR2 I;  1HNX I;  4DV4 I;  4XTJ A;  1RR9 A;  1Y4U A;  1A6F A;  4JI6 I;  4DR4 I;  3GON A;  2ZM6 E;  1HR0 E;  2J7K A;  4DR3 E;  1H7S A;  3WU3 A;  4LF7 E;  4DPX A;  4LCF A;  2PO2 A;  4DR1 I;  2HK2 A;  1HNZ I;  1N32 E;  5K36 B;  2GO4 A;  1N34 I;  2J65 A;  2O1T A;  2O1U A;  3OTO E;  1FJG E;  4JI3 E;  1QZR A;  4OO1 D;  1H7U A;  4B3S I;  4K0K I;  1N36 E;  2C37 A;  1I94 I;  5EKW A;  2X36 A;  4NXM I;  3L7Z A;  2IES A;  4B3M E;  5JEA D;  3T1Y E;  5C0X B;  4IFD C;  1UDS A;  4FWH A;  2NN6 A;  4FWD A;  2BR2 B;  4IFD A;  2XEX A;  2UXB I;  4LOM A;  4JI7 I;  1KVK A;  4DV5 I;  4JI2 E;  4LF6 E;  4OO1 E;  4USK A;  4LPF A;  1ZM4 A;  3WU4 A;  4NBQ A;  4X64 E;  5JEA E;  3J7A M;  4QNK A;  4LF9 E;  2NN6 D;  1XNQ I;  2JE6 B;  2UU9 I;  4HAC B;  4MU0 A;  3KRN A;  4DV7 I;  3HKM A;  4FW4 A;  4LFC E;  2VES A;  5A2Q Q;  1XMQ I;  4KQV A;  1ZM9 A;  4PU9 A;  2IOP A;  2NN6 E;  3OTO I;  2PNM A;  1VI7 A;  4DV0 I;  4DPW A;  4LF8 E;  2BA1 D;  1J5E I;  5K36 C;  4GKK E;  2CG9 A;  5K36 A;  4I3H A;  1MG7 A;  3T1H I;  1USU A;  4X65 I;  4DV1 I;  4LF4 E;  4X66 E;  2V2Z A;  2Z5C A;  2UXC E;  4DPT A;  5LMN I;  1XMO E;  2V8P A;  5DRO A;  3V5R A;  1XNR E;  1Y5Y A;  4LCG A;  1FWK A;  2O1W A;  1HNX E;  5C0X C;  4AQY I;  4DV4 E;  2DEI A;  2PO2 B;  4JYA E;  4DUZ I;  4LF5 I;  4DR4 E;  1R6M A;  4JI6 E;  4IZK A;  3ZZU A;  2C38 A;  1RRE A;  4J3D A;  4DR1 E;  2R3V A;  1FKA E;  1HNZ E;  3M6A A;  5GMD A;  1UEK A;  3L7Z B;  1N34 E;  1ELO A;  1N0U A;  1RHY A;  2NN6 B;  4B3S E;  4K0K E;  2HFS A;  4MYU A;  1I94 E;  4DV6 I;  4LCH A;  4NXM E;  4NXN I;  1IBM I;  4DR6 E;  3B82 A;  4ZVI A;  1H74 A;  2HKE A;  3B78 A;  4P52 A;  4LFB I;  1UDQ A;  2UXB E;  2A2C A;  1NHH A;  4JI7 E;  4Z7C A;  3NZK A;  4X66 I;  4DV5 E;  1HNW I;  1HK7 A;  4DV2 I;  1XNR I;  4KHP I;  3UHM A;  5DRR A;  3B8H A;  1OJ4 A;  1Y6Z A;  3J80 Q;  2AJ4 A;  3CDJ A;  4JYA I;  1EA6 A;  4OO1 C;  3DD6 A;  1XNQ E;  4OO1 A;  4UT4 A;  3PYE A;  1PIE A;  4QNJ A;  2HK3 A;  4AIM A;  2IER A;  2UU9 E;  4DV7 E;  5FLX Q;  2HKJ A;  1OYP A;  5JEA C;  3M7N G;  2CZ9 A;  5JEA A;  4MDT A;  1NHJ A;  4DPY A;  1B62 A;  1XMQ E;  1MX0 A;  3P76 A;  5LMU I;  4JI4 E;  2PNL A;  4FW7 A;  4IS9 A;  4WUD A;  4DV0 E;  1KIJ A;  2Z5C B;  4BA1 A;  1J5E E;  2F4V I;  4JI1 E;  4JV5 I;  5ELW A;  1ZXN A;  3P3E A;  3T1H E;  4DR6 I;  4X65 E;  4DV1 E;  2NN6 C;  2JEA A;  4GQU A;  5IT9 Q;  4MU3 A;  5LMN E;  4HYM A;  4JG4 A;  1Z59 A;  4YHH I;  1N33 I;  4IZK B;  1Z0B A;  2C38 B;  4URL A;  4DR7 I;  3J80 C;  2VQE I;  2BV3 A;  4AQY E;  4FW5 A;  4M1K A;  1Z0G A;  4MQY A;  4P7A A;  4FWG A;  4DUZ E;  4LF5 E;  2X7I A;  4X62 I;  4USM A;  3M85 G;  2VF3 A;  1S16 A;  4MYT A;  4YY3 I;  5FLX C;  4B3T I;  1PKP A;  3HUL A;  3PRY A;  2Z5B A;  2WW4 A;  3PYD A;  5DNX A;  3V2U C;  1ZXM A;  2UUB I;  4JI4 I;  1S4E A;  2IOQ A;  3P3G A;  4DV6 E;  2UUA E;  2PO1 A;  4NXN E;  1IBM E;  4JI1 I;  1UDN A;  5IWA I;  4IFD F;  5IT9 C;  4LFB E;  1H73 A;  1FWL A;  4HY1 A;  3JAM Q;  3QT8 A;  2BM0 A;  1HNW E;  2GS8 A;  4DV2 E;  4OO1 B;  1UDO A;  4KHP E;  1Z5B A;  3GLL A;  3CWV A;  4PRV A;  4LFA I;  5FWK A;  5JEA B;  3HJC A;  2BA0 D;  3B4T A;  3GCM A;  3QT6 A;  3LNU A;  2VQF I;  4JI0 E;  4BA1 B;  5DRQ A;  5A2Q C;  3QT7 A;  5LMU E;  5LL6 R;  4JI5 I;  2JEA B;  2HFU A;  4ED4 A;  4FW9 A;  3ZM7 A;  5K36 F;  3Q1Q A;  2F4V E;  4JV5 E;  3LTO A;  4IZJ D;  3WU5 A;  2UUA I;  4AID A;  1KKH A;  1IBK I;  4MU4 A;  4FW6 A;  2C39 B;  2OI2 A;  3JAM C;  3ZZ0 A;  4DV3 I;  4EMD A;  4YHH E;  1N33 E;  1WUU A;  2BA1 G;  2A2D A;  2Z5E A;  4UTG A;  4MU1 A;  5C0X D;  4DR7 E;  5C0X F;  3Q6N A;  2JEB B;  2VQE E;  2GO3 A;  2WP8 A;  4JI8 I;  4Z7Y A;  4X62 E;  2E5L I;  2Z5B B;  3K1J A;  3LPS A;  3ZZT A;  3ZKB A;  3ZKD A;  5DRP A;  4YY3 E;  4B3T E;  3U1K A;  1Z0E A;  2LJP A;  1PVG A;  1E3H A;  1YHC A;  4JI0 I;  3U1Y A;  2PO1 B;  3PYF A;  5DNL A;  1D6T A;  1DAR A;  4OKG A;  2UUB E;  3K85 A;  2UUC I;  5L3J A;  2V34 A;  1Z5C A;  1IBL E;  4WUC A;  4FN5 A;  1YH8 A;  5GME A;  5IWA E;  2JT2 A;  1Z5A A;  4BA2 A;  2BM1 A;  1B63 A;  2O1V A;  4GKJ I;  2HHH I;  1Z0T A;  2F1D A;  1U2R A;  4N3O A;  1USV A;  2R42 A;  1OYR A;  4IZJ B;  4DUY E;  4DR5 I;  4B3R I;  1R6L A;  2C39 A;  4DPU A;  4LFA E;  4OO1 F;  3PS1 A;  1XXE A;  2PO0 A;  1Y60 A;  2PNZ A;  4OX9 E;  4FW3 A;  2E1R A;  2VQF E;  2JEB A;  4U3B A;  3PYG A;  5JEA F;  2WNR A;  1FNM A;  4DU7 A;  1P42 A;  5BR8 I;  4JI5 E;  3H4L A;  2O3Z A;  4PRX A;  3CDI A;  1VIS A;  1NHI A;  4ISA A;  1Z0V A;  1ZM2 A;  4DXL A;  3PS3 A;  2ZBK B;  1IBL I;  1IBK E;  5EL9 A;  3P3C A;  2NN6 F;  3Q6M A;  1NZ0 A;  2WP8 B;  4IFD D;  1ZM3 A;  1BKN A;  2ZM6 I;  1HR0 I;  4DV3 E;  4DR3 I;  4LF7 I;  3K17 A;  4DU8 A;  2UXD E;  1N0V C;  3H1C A;  4WUB A;  2CVE A;  3D4J A;  1N32 I;  2ZIT A;  4JI8 E;  4DUY I;  2E5L E;  1FJG I;  4HXZ A;  1XHK A;  4RPF A;  4JI3 I;  4IFD E;  1N36 I;  1K47 A;  3J81 Q;  4OX9 I;  4B3M I;  4IZJ A;  2V2Q A;  2GQ0 A;  3T1Y I;  1MU5 A;  1Y4S A;  2UUC E;  4U3D A;  4BA2 B;  4JI2 I;  4LF6 I;  1H72 C;  2DEJ A;  4DR2 E;  3J7A G;  1Z0W A;  5C0X A;  5K36 D;  2BR2 A;  4X64 I;  3M7N D;  1Z0C A;  4LF9 I;  4AM3 A;  1EI1 A;  4GKJ E;  4OZE A;  2HHH E;  2CGE A;  2C37 B;  3PS2 A;  3WU6 A;  2PO0 B;  2UXD I;  2PNZ B;  2Q2E B;  5K36 E;  4LFC I;  1KTV A;  3P06 A;  4DR5 E;  4B3R E;  2WNR B;  2JE6 A;  3QT5 A;  1E3P A;  2NPF A;  2EFG A;  2V2V A;  4IFD B;  2AE8 A;  4HAC A;  3J81 C;  4LF8 I;  4R1F A;  4GKK I; 
#chains in the Genus database with same CATH homology
 2F1D A;  2AE8 A;  5EKW A;  4GQU A;  4MU4 A;  4LPF A;  1RHY A;  5ELW A;  4QNK A;  4MU3 A;  4QNJ A;  4MU0 A;  4LOM A;  5DNX A;  5DNL A;  5EL9 A;  4MU1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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