4OZEA

A.aolicus lpxc in complex with native product
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFCFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic insight from the crystal structure of A.aolicus LpxC in the presence of product
rcsb
molecule tags Hydrolase
source organism Aquifex aeolicus
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 95
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2014-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4ozeA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4ozeA02
3P3CA 4FW3A 4LCHA 2IESA 4OKGA 3P3GA 4OZEA 2J65A 4MDTA 1YH8A 2GO3A 3PS2A 1P42A 4FW4A 5DRQA 2VESA 3PS1A 4FW6A 3U1YA 2O3ZA 4U3DA 3PS3A 2GO4A 1XXEA 4LCFA 1YHCA 4FW7A 4U3BA 3NZKA 4IS9A 5DRPA 4ISAA 4MQYA 3P76A 4J3DA 3UHMA 5DROA 4FW5A 2IERA 2JT2A 4LCGA 3P3EA 5DRRA
chains in the Genus database with same CATH superfamily
3Q6MA 5LMUE 4DR4I 2E1RA 4JI8I 4JI5I 1B63A 4DR2I 3P3GA 4MU4A 3H1CA 4LFAI 2HFSA 1NZ0A 5DNXA 1UDQA 3K1JA 2BA0D 4FW4A 2VQEE 2VESA 1OYPA 5BR8I 4LF5I 1XNQI 3F0NA 5A2QQ 3JAMQ 2IOQA 1USVA 4DV3E 2C37A 2WNRA 4DV2E 4YY3I 2UUAI 3ZKDA 2UXCE 3CDJA 2UUCI 5EKWA 4DV7I 4JI3I 3J81C 4DV6I 2O1WA 4LFCI 5C0XE 3J80Q 4OO1C 1FI4A 2V2VA 1HNWI 1MG7A 4B3MI 3L7ZA 4DV4E 5JEAF 2X7IA 5EL9A 2Z5BA 1ELOA 3K85A 4JI4I 5JEAD 4X62E 3GLLA 4ISAA 4XTJA 5L3JA 1N0VC 2UXDE 1IBME 4JI7E 3P3CA 4LF8I 1Z0GA 4HACA 4IZKB 4DR6I 2IESA 1J5EI 4JI0I 2CGEA 4UTGA 4MYTA 1YH8A 3LTOA 1HNXI 2V2QA 2R3VA 4JI2E 1MX0A 3QT8A 5DRPA 5C0XB 2C39B 4DPWA 1RHYA 2AJ4A 2UU9E 3WU3A 3P3EA 3ZZTA 2V2ZA 1KIJA 1USUA 2Q2EB 1HK7A 2OI2A 3B8HA 1D6TA 5GMDA 1FJGI 2BA0G 4B3RE 2NN6C 4QNJA 4DV3I 2O1VA 4IZJA 2JEAA 3CDIA 5JEAA 1R6MA 1EA6A 1Y6ZA 4B3SI 4LFBE 2VQFE 3B78A 3WU4A 4RPFA 4P52A 3P76A 4JI1E 1XNRI 4IFDF 4PRVA 5K36E 2DEJA 3PYDA 3HULA 3OTOE 4IFDD 4FW3A 5FLXC 2AE8A 3U1KA 4HY1A 1Y4UA 1PKPA 3PYFA 2GQ0A 4X62I 4GQUA 4USKA 4GKKE 5LMNE 1PIEA 5FWKA 4MU0A 2C38B 4OX9E 4JYAE 3CWVA 2UXDI 3Q1QA 4X65E 1HR0E 2JE6A 5C0XD 5ELWA 4NXNE 1H74A 1N34I 3B4TA 3V5RA 2PO1B 2HHHE 2J7KA 4JI2I 2WP8A 4OKGA 3PYGA 2ZBKB 2HKEA 1FWKA 3Q6NA 4KQVA 5C0XC 4OO1F 3M6AA 2PNZA 3P06A 1N33E 1XMQE 2PNMA 1Z0VA 1N36I 1IBLI 4OO1D 1MU5A 4NXME 4J3DA 2NN6B 1XHKA 3M85D 4IFDA 2HFUA 4YHHE 4WUCA 4URLA 3T1HE 2O1UA 4DUYI 4DV5I 4X66E 1UDNA 3QT7A 4ZVIA 3T1YE 2E5LI 4LF6E 2BV3A 4LOMA 4MDTA 4DR7E 4DR3I 2HK2A 4AQYE 1P42A 1HNZI 3J7AG 2UUBE 5DRQA 4JV5E 1Z5AA 3U1YA 1Z0BA 2C39A 3DD6A 3OTOI 3J81Q 2F4VI 5IWAE 4N3OA 4FW5A 2IERA 1Z5BA 2O3ZA 3PYEA 2JEBB 4FWHA 4K0KE 4GKKI 2Z5CA 1VISA 4DV1I 1Z59A 3B82A 1E3HA 1QZRA 2HKJA 2BR2A 4LF4E 1OYSA 4OO1A 1FWLA 2X36A 1N32I 2BA1D 4Z7YA 2NN6F 2ZM6I 4LF9E 2PO2A 1S4EA 2HHHI 4BA1A 2PO0A 5LMUI 4MYUA 2NN6D 2C37B 2WNRB 2JT2A 2CZ9A 4GKJE 1IBKE 5K36C 5IT9C 2VQEI 1XMOE 2J65A 4DR4E 4JI8E 4JI5E 1E3PA 1OJ4A 3L7ZB 4PU9A 4DR2E 1VI7A 4BA2A 4LFAE 4DV2I 2GS8A 1XXEA 4NBQA 4AIDA 2UXCI 4FW7A 4DUZE 3M85G 3V2UC 1KKHA 4B3TE 1U2RA 5BR8E 3T1YI 1XNQE 5IT9Q 1ZXMA 5DROA 2PO1A 2Z5EA 5JEAE 4LF6I 4DXLA 4JG4A 4LCGA 4DR7I 4DV4I 2BM0A 4Z7CA 4YY3E 2UUAE 2UUCE 1ZM2A 4DV7E 3D4JA 4JI3E 1H73A 1B62A 5GMEA 3LPSA 2V34A 4DU7A 4ED4A 1HNWE 4WUDA 4B3ME 1R6LA 5C0XF 2NN6A 1IBMI 4K0KI 4JI7I 2WW4A 5FLXQ 3WU5A 3UHMA 4JI4E 2BM1A 2NPFA 3GONA 4DPUA 4LCHA 4LF7E 1ZXNA 4KHPE 4OZEA 1DARA 4LF8E 4LF9I 1UEKA 2BA1G 1K47A 1FNMA 1J5EE 4JI0E 2JEAB 4IZJB 2UXBE 5K36B 2GO4A 2UU9I 4R1FA 1HNXE 1Y5YA 1H72C 4USMA 4M1KA 1I94E 1KVKA 1XMOI 5A2QC 5DRRA 4IZKA 3JAMC 2HK3A 4DU8A 4B3RI 4FN5A 4FW9A 1Z0CA 1EI1A 4QNKA 2VF3A 2V8PA 4IFDE 3HJCA 4DUZI 4LFBI 4DR1E 2VQFI 4LPFA 3J80C 4B3TI 3M7ND 4JI1I 4FW6A 1ZM9A 4HXZA 4MU3A 1FJGE 2XEXA 5C0XA 2DEIA 4U3BA 4MQYA 4B3SE 2JE6B 4PRXA 4UT4A 3PRYA 1XNRE 5LMNI 4DR5E 1WUUA 4DPTA 3J7AM 1ZM4A 2WP8B 4OX9I 4JYAI 2PNLA 4JI6E 4DPXA 5K36F 1ZM3A 1Z0EA 2EFGA 3ZKBA 4FWDA 4X65I 2PNZB 3ZZUA 1HR0I 4DV0E 1UDOA 4NXNI 4IZJD 5K36D 2A2CA 4X64E 3NZKA 2CVEA 3QT5A 4LF7I 1KTVA 1RR9A 4P7AA 4OO1E 4KHPI 1Z0TA 2R42A 4IFDB 1UDSA 4DPYA 3HKMA 1N34E 5JEAC 1H7SA 1N33I 2CG9A 2UXBI 1BKNA 3WU6A 1XMQI 1FKAE 4MU1A 2GO3A 2C38A 3QT6A 4NXMI 1I94I 4U3DA 4YHHI 3T1HI 2Z5BB 1PVGA 1Y60A 4X66I 1N36E 4LF5E 1IBLE 4I3HA 5LL6R 3LNUA 4DR1I 1Z5CA 3K17A 1S16A 4EMDA 4WUBA 4AQYI 2Z5CB 1A6FA 2UUBI 1RREA 4JV5I 3GCMA 4HACB 4DUYE 4DV5E 3M7NG 4DV6E 2E5LE 2BR2B 3PS2A 3ZZ0A 4LFCE 3GMEA 5K36A 1Z0WA 5IWAI 4OO1B 2IOPA 3PS3A 2F1DA 4DR3E 1OYRA 1HNZE 4IS9A 2PO2B 4DR5I 4BA1B 2O1TA 2PO0B 2LJPA 3H4LA 2F4VE 1Y4SA 4JI6I 4LF4I 5DNLA 2NN6E 2ZITA 4FWGA 4DV0I 4DV1E 4HYMA 4X64I 1NHJA 3ZM7A 4DR6E 3PS1A 4IFDC 1NHHA 4LCFA 5JEAB 4BA2B 1N0UA 1YHCA 1H7UA 1NHIA 3KRNA 1N32E 2A2DA 4GKJI 1IBKI 2ZM6E 4AM3A 2JEBA 4AIMA
chains in the Genus database with same CATH topology
3P3CA 4FW3A 4LCHA 2IESA 4OKGA 3P3GA 4OZEA 2J65A 4MDTA 1YH8A 2GO3A 3PS2A 1P42A 4FW4A 5DRQA 2VESA 3PS1A 4FW6A 3U1YA 2O3ZA 4U3DA 3PS3A 2GO4A 1XXEA 4LCFA 1YHCA 4FW7A 4U3BA 3NZKA 4IS9A 5DRPA 4ISAA 4MQYA 3P76A 4J3DA 3UHMA 5DROA 4FW5A 2IERA 2JT2A 4LCGA 3P3EA 5DRRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P3C A;  4FW3 A;  4LCH A;  2IES A;  4OKG A;  3P3G A;  4OZE A;  2J65 A;  4MDT A;  1YH8 A;  2GO3 A;  3PS2 A;  1P42 A;  4FW4 A;  5DRQ A;  2VES A;  3PS1 A;  4FW6 A;  3U1Y A;  2O3Z A;  4U3D A;  3PS3 A;  2GO4 A;  1XXE A;  4LCF A;  1YHC A;  4FW7 A;  4U3B A;  3NZK A;  4IS9 A;  5DRP A;  4ISA A;  4MQY A;  3P76 A;  4J3D A;  3UHM A;  5DRO A;  4FW5 A;  2IER A;  2JT2 A;  4LCG A;  3P3E A;  5DRR A; 
#chains in the Genus database with same CATH topology
 3Q6M A;  5LMU E;  4DR4 I;  2E1R A;  4JI8 I;  4JI5 I;  1B63 A;  4DR2 I;  3P3G A;  4MU4 A;  3H1C A;  4LFA I;  2HFS A;  1NZ0 A;  5DNX A;  1UDQ A;  3K1J A;  2BA0 D;  4FW4 A;  2VQE E;  2VES A;  1OYP A;  5BR8 I;  4LF5 I;  1XNQ I;  3F0N A;  5A2Q Q;  3JAM Q;  2IOQ A;  1USV A;  4DV3 E;  2C37 A;  2WNR A;  4DV2 E;  4YY3 I;  2UUA I;  3ZKD A;  2UXC E;  3CDJ A;  2UUC I;  5EKW A;  4DV7 I;  4JI3 I;  3J81 C;  4DV6 I;  2O1W A;  4LFC I;  5C0X E;  3J80 Q;  4OO1 C;  1FI4 A;  2V2V A;  1HNW I;  1MG7 A;  4B3M I;  3L7Z A;  4DV4 E;  5JEA F;  2X7I A;  5EL9 A;  2Z5B A;  1ELO A;  3K85 A;  4JI4 I;  5JEA D;  4X62 E;  3GLL A;  4ISA A;  4XTJ A;  5L3J A;  1N0V C;  2UXD E;  1IBM E;  4JI7 E;  3P3C A;  4LF8 I;  1Z0G A;  4HAC A;  4IZK B;  4DR6 I;  2IES A;  1J5E I;  4JI0 I;  2CGE A;  4UTG A;  4MYT A;  1YH8 A;  3LTO A;  1HNX I;  2V2Q A;  2R3V A;  4JI2 E;  1MX0 A;  3QT8 A;  5DRP A;  5C0X B;  2C39 B;  4DPW A;  1RHY A;  2AJ4 A;  2UU9 E;  3WU3 A;  3P3E A;  3ZZT A;  2V2Z A;  1KIJ A;  1USU A;  2Q2E B;  1HK7 A;  2OI2 A;  3B8H A;  1D6T A;  5GMD A;  1FJG I;  2BA0 G;  4B3R E;  2NN6 C;  4QNJ A;  4DV3 I;  2O1V A;  4IZJ A;  2JEA A;  3CDI A;  5JEA A;  1R6M A;  1EA6 A;  1Y6Z A;  4B3S I;  4LFB E;  2VQF E;  3B78 A;  3WU4 A;  4RPF A;  4P52 A;  3P76 A;  4JI1 E;  1XNR I;  4IFD F;  4PRV A;  5K36 E;  2DEJ A;  3PYD A;  3HUL A;  3OTO E;  4IFD D;  4FW3 A;  5FLX C;  2AE8 A;  3U1K A;  4HY1 A;  1Y4U A;  1PKP A;  3PYF A;  2GQ0 A;  4X62 I;  4GQU A;  4USK A;  4GKK E;  5LMN E;  1PIE A;  5FWK A;  4MU0 A;  2C38 B;  4OX9 E;  4JYA E;  3CWV A;  2UXD I;  3Q1Q A;  4X65 E;  1HR0 E;  2JE6 A;  5C0X D;  5ELW A;  4NXN E;  1H74 A;  1N34 I;  3B4T A;  3V5R A;  2PO1 B;  2HHH E;  2J7K A;  4JI2 I;  2WP8 A;  4OKG A;  3PYG A;  2ZBK B;  2HKE A;  1FWK A;  3Q6N A;  4KQV A;  5C0X C;  4OO1 F;  3M6A A;  2PNZ A;  3P06 A;  1N33 E;  1XMQ E;  2PNM A;  1Z0V A;  1N36 I;  1IBL I;  4OO1 D;  1MU5 A;  4NXM E;  4J3D A;  2NN6 B;  1XHK A;  3M85 D;  4IFD A;  2HFU A;  4YHH E;  4WUC A;  4URL A;  3T1H E;  2O1U A;  4DUY I;  4DV5 I;  4X66 E;  1UDN A;  3QT7 A;  4ZVI A;  3T1Y E;  2E5L I;  4LF6 E;  2BV3 A;  4LOM A;  4MDT A;  4DR7 E;  4DR3 I;  2HK2 A;  4AQY E;  1P42 A;  1HNZ I;  3J7A G;  2UUB E;  5DRQ A;  4JV5 E;  1Z5A A;  3U1Y A;  1Z0B A;  2C39 A;  3DD6 A;  3OTO I;  3J81 Q;  2F4V I;  5IWA E;  4N3O A;  4FW5 A;  2IER A;  1Z5B A;  2O3Z A;  3PYE A;  2JEB B;  4FWH A;  4K0K E;  4GKK I;  2Z5C A;  1VIS A;  4DV1 I;  1Z59 A;  3B82 A;  1E3H A;  1QZR A;  2HKJ A;  2BR2 A;  4LF4 E;  1OYS A;  4OO1 A;  1FWL A;  2X36 A;  1N32 I;  2BA1 D;  4Z7Y A;  2NN6 F;  2ZM6 I;  4LF9 E;  2PO2 A;  1S4E A;  2HHH I;  4BA1 A;  2PO0 A;  5LMU I;  4MYU A;  2NN6 D;  2C37 B;  2WNR B;  2JT2 A;  2CZ9 A;  4GKJ E;  1IBK E;  5K36 C;  5IT9 C;  2VQE I;  1XMO E;  2J65 A;  4DR4 E;  4JI8 E;  4JI5 E;  1E3P A;  1OJ4 A;  3L7Z B;  4PU9 A;  4DR2 E;  1VI7 A;  4BA2 A;  4LFA E;  4DV2 I;  2GS8 A;  1XXE A;  4NBQ A;  4AID A;  2UXC I;  4FW7 A;  4DUZ E;  3M85 G;  3V2U C;  1KKH A;  4B3T E;  1U2R A;  5BR8 E;  3T1Y I;  1XNQ E;  5IT9 Q;  1ZXM A;  5DRO A;  2PO1 A;  2Z5E A;  5JEA E;  4LF6 I;  4DXL A;  4JG4 A;  4LCG A;  4DR7 I;  4DV4 I;  2BM0 A;  4Z7C A;  4YY3 E;  2UUA E;  2UUC E;  1ZM2 A;  4DV7 E;  3D4J A;  4JI3 E;  1H73 A;  1B62 A;  5GME A;  3LPS A;  2V34 A;  4DU7 A;  4ED4 A;  1HNW E;  4WUD A;  4B3M E;  1R6L A;  5C0X F;  2NN6 A;  1IBM I;  4K0K I;  4JI7 I;  2WW4 A;  5FLX Q;  3WU5 A;  3UHM A;  4JI4 E;  2BM1 A;  2NPF A;  3GON A;  4DPU A;  4LCH A;  4LF7 E;  1ZXN A;  4KHP E;  4OZE A;  1DAR A;  4LF8 E;  4LF9 I;  1UEK A;  2BA1 G;  1K47 A;  1FNM A;  1J5E E;  4JI0 E;  2JEA B;  4IZJ B;  2UXB E;  5K36 B;  2GO4 A;  2UU9 I;  4R1F A;  1HNX E;  1Y5Y A;  1H72 C;  4USM A;  4M1K A;  1I94 E;  1KVK A;  1XMO I;  5A2Q C;  5DRR A;  4IZK A;  3JAM C;  2HK3 A;  4DU8 A;  4B3R I;  4FN5 A;  4FW9 A;  1Z0C A;  1EI1 A;  4QNK A;  2VF3 A;  2V8P A;  4IFD E;  3HJC A;  4DUZ I;  4LFB I;  4DR1 E;  2VQF I;  4LPF A;  3J80 C;  4B3T I;  3M7N D;  4JI1 I;  4FW6 A;  1ZM9 A;  4HXZ A;  4MU3 A;  1FJG E;  2XEX A;  5C0X A;  2DEI A;  4U3B A;  4MQY A;  4B3S E;  2JE6 B;  4PRX A;  4UT4 A;  3PRY A;  1XNR E;  5LMN I;  4DR5 E;  1WUU A;  4DPT A;  3J7A M;  1ZM4 A;  2WP8 B;  4OX9 I;  4JYA I;  2PNL A;  4JI6 E;  4DPX A;  5K36 F;  1ZM3 A;  1Z0E A;  2EFG A;  3ZKB A;  4FWD A;  4X65 I;  2PNZ B;  3ZZU A;  1HR0 I;  4DV0 E;  1UDO A;  4NXN I;  4IZJ D;  5K36 D;  2A2C A;  4X64 E;  3NZK A;  2CVE A;  3QT5 A;  4LF7 I;  1KTV A;  1RR9 A;  4P7A A;  4OO1 E;  4KHP I;  1Z0T A;  2R42 A;  4IFD B;  1UDS A;  4DPY A;  3HKM A;  1N34 E;  5JEA C;  1H7S A;  1N33 I;  2CG9 A;  2UXB I;  1BKN A;  3WU6 A;  1XMQ I;  1FKA E;  4MU1 A;  2GO3 A;  2C38 A;  3QT6 A;  4NXM I;  1I94 I;  4U3D A;  4YHH I;  3T1H I;  2Z5B B;  1PVG A;  1Y60 A;  4X66 I;  1N36 E;  4LF5 E;  1IBL E;  4I3H A;  5LL6 R;  3LNU A;  4DR1 I;  1Z5C A;  3K17 A;  1S16 A;  4EMD A;  4WUB A;  4AQY I;  2Z5C B;  1A6F A;  2UUB I;  1RRE A;  4JV5 I;  3GCM A;  4HAC B;  4DUY E;  4DV5 E;  3M7N G;  4DV6 E;  2E5L E;  2BR2 B;  3PS2 A;  3ZZ0 A;  4LFC E;  3GME A;  5K36 A;  1Z0W A;  5IWA I;  4OO1 B;  2IOP A;  3PS3 A;  2F1D A;  4DR3 E;  1OYR A;  1HNZ E;  4IS9 A;  2PO2 B;  4DR5 I;  4BA1 B;  2O1T A;  2PO0 B;  2LJP A;  3H4L A;  2F4V E;  1Y4S A;  4JI6 I;  4LF4 I;  5DNL A;  2NN6 E;  2ZIT A;  4FWG A;  4DV0 I;  4DV1 E;  4HYM A;  4X64 I;  1NHJ A;  3ZM7 A;  4DR6 E;  3PS1 A;  4IFD C;  1NHH A;  4LCF A;  5JEA B;  4BA2 B;  1N0U A;  1YHC A;  1H7U A;  1NHI A;  3KRN A;  1N32 E;  2A2D A;  4GKJ I;  1IBK I;  2ZM6 E;  4AM3 A;  2JEB A;  4AIM A; 
#chains in the Genus database with same CATH homology
 3P3C A;  4FW3 A;  4LCH A;  2IES A;  4OKG A;  3P3G A;  4OZE A;  2J65 A;  4MDT A;  1YH8 A;  2GO3 A;  3PS2 A;  1P42 A;  4FW4 A;  5DRQ A;  2VES A;  3PS1 A;  4FW6 A;  3U1Y A;  2O3Z A;  4U3D A;  3PS3 A;  2GO4 A;  1XXE A;  4LCF A;  1YHC A;  4FW7 A;  4U3B A;  3NZK A;  4IS9 A;  5DRP A;  4ISA A;  4MQY A;  3P76 A;  4J3D A;  3UHM A;  5DRO A;  4FW5 A;  2IER A;  2JT2 A;  4LCG A;  3P3E A;  5DRR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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