4FW6A

Crystal structure of the lpxc in complex with n-[(2s,3r)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(phenylethynyl)benzamide inhibitor
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
300
structure length
300
Chain Sequence
AMIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the LpxC
rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Pseudomonas aeruginosa
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 88
structure length 300
sequence length 300
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2012-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4fw6A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4fw6A02
2IERA 4OKGA 3U1YA 3PS2A 4IS9A 2GO3A 3P3EA 4OZEA 3P3GA 3P3CA 4J3DA 4LCHA 4MDTA 5DROA 3NZKA 3PS1A 2JT2A 4FW3A 4FW4A 4LCGA 4FW6A 4FW5A 3P76A 4U3BA 2J65A 1YH8A 4MQYA 2O3ZA 2VESA 5DRQA 2IESA 4FW7A 3UHMA 2GO4A 1P42A 4U3DA 1XXEA 3PS3A 5DRPA 4LCFA 4ISAA 5DRRA 1YHCA
chains in the Genus database with same CATH superfamily
2GS8A 4JI7E 3JAMQ 4X62E 1KTVA 5EKWA 1RREA 4MU3A 2WNRA 4X64E 4LF4I 2V8PA 2PO2A 4LF7E 5DROA 4B3RI 3GONA 2VQEE 4AM3A 4DUYE 3J81Q 4NBQA 4X65E 1USVA 4JI3I 1FNMA 3UHMA 2HFSA 2NN6C 4JG4A 1ZM3A 4DU7A 3T1HI 2BA1G 1IBMI 1XNQI 2UUAI 1I94E 3Q1QA 5IWAI 1E3HA 5C0XE 2BV3A 3V2UC 4JI7I 4X62I 1E3PA 4HXZA 4X64I 3GLLA 4NXNE 4J3DA 1N0VC 4LF7I 1B63A 1HNWE 1MX0A 2O1TA 1HR0E 3M6AA 5FLXQ 2EFGA 4DUYI 3P76A 4U3BA 2C37B 5JEAA 1UDQA 1Z0TA 1N32I 4LF6E 2WW4A 4QNKA 1UDOA 1YHCA 1I94I 2BM1A 4BA2B 4LF8E 3B82A 2IERA 2R42A 4GKJE 3QT6A 1KKHA 4USKA 4NXNI 2V2QA 2PNMA 3HULA 4DV5I 1HR0I 4AIMA 4JI6E 4IFDA 4IZJA 4K0KI 1ZM4A 1IBLE 1H74A 3GMEA 1HNZI 4LF6I 5JEAC 3OTOI 4ISAA 4LFCI 3V5RA 4LF8I 5A2QQ 1OYPA 5C0XB 2UXDI 4OO1A 4DR5E 1U2RA 4DPYA 3HJCA 4DR1I 3CDIA 2ZBKB 1UDSA 2AE8A 3K1JA 4MU0A 4DV4E 1N33E 5K36A 2BM0A 4JI6I 2JE6B 4X66E 1IBKE 3B8HA 4DR3E 1NHIA 4PRXA 3ZZTA 2Q2EB 1NHJA 4GQUA 4IFDC 5BR8I 1MU5A 4R1FA 1Z5CA 2BA1D 4P52A 1K47A 2C39B 5EL9A 4PRVA 2NN6E 3ZKDA 4AQYE 4DR5I 2HK2A 3PYDA 1Y60A 4HY1A 2O1UA 4IZJB 4B3RE 3ZM7A 1Z0VA 5IT9C 1IBKI 4DR3I 1YH8A 4EMDA 4JI5E 2O1WA 4BA1B 4FW7A 2Z5BB 1UDNA 1PVGA 4B3SE 1IBME 1ZM2A 2UUAE 4OO1B 2CGEA 4KHPE 1HK7A 2VF3A 5IWAE 3WU3A 5K36B 3WU6A 2Z5EA 3P3EA 4AQYI 2UUBI 2VQFE 5C0XD 1RHYA 1UEKA 4JI5I 1N34I 1FWKA 2A2CA 1R6LA 1XMOI 2PNZA 1FJGE 4DUZE 4OX9E 1N32E 3PYEA 4USMA 4IZKA 1P42A 4B3SI 4LF5E 3B78A 4HACB 1USUA 4MYTA 5C0XF 4KHPI 3J80Q 2LJPA 4ED4A 3WU5A 1D6TA 3J81C 2NN6B 5JEAE 1EA6A 2AJ4A 2IOPA 1OYSA 2PO0B 2HFUA 2VQFI 4DV0E 4DV5E 4LFAE 1WUUA 4Z7CA 4UT4A 5LMNE 3U1KA 2O1VA 4DV2E 4IZJD 4RPFA 4K0KE 1FJGI 4DUZI 4OX9I 1HNZE 3ZKBA 4LF5I 5LMUI 2A2DA 4XTJA 3OTOE 2E5LE 4LFCE 2F4VI 2WNRB 3H4LA 4DV1E 2WP8A 2PO2B 2Z5CA 4IFDE 1QZRA 2UXDE 2ZM6I 4OO1D 1ZXMA 1Y5YA 1KIJA 3P06A 4DR1E 1PKPA 4P7AA 4DV0I 2PNZB 4LFAI 5GMDA 5K36D 4IZKB 1NHHA 3T1YI 4DR6E 5LMNI 2J65A 1Z0GA 2VESA 4URLA 4DV2I 4JI2I 5BR8E 4OO1F 4OO1E 4JI1I 2E5LI 3ZZ0A 2HKJA 5K36F 4DV1I 2DEIA 1XMQI 4N3OA 5K36E 3U1YA 2HHHE 1OYRA 1B62A 2JEAA 4DPTA 5JEAB 4WUDA 1J5EE 4FW6A 4LF9E 1Y6ZA 1Z0BA 1HNXI 3CWVA 2R3VA 4DR6I 2UU9I 2NN6D 1FWLA 3LNUA 2O3ZA 3M85G 4JYAE 3L7ZA 4MU4A 4B3ME 3J7AG 3CDJA 2X7IA 1Z59A 4ZVIA 3Q6MA 3K17A 4OKGA 3H1CA 2NN6F 2HHHI 2DEJA 1S16A 4IFDB 2OI2A 2UUBE 2UXBE 1Z0WA 3WU4A 4DXLA 4DV3I 4JI4I 1J5EI 4JI0I 4FW5A 4LF9I 4LPFA 2UUCE 4JYAI 2IOQA 3PRYA 1N34E 1XMOE 3QT8A 2BA0G 4B3MI 3GCMA 1XNRE 1VI7A 4FWHA 5L3JA 2V34A 3P3GA 4OZEA 4LCHA 1VISA 2UXBI 3J7AM 3LPSA 3PS1A 4FWGA 5DNLA 2PO1A 1Y4SA 3F0NA 4LFBE 2UUCI 2BR2A 4YHHE 1ELOA 1R6MA 5JEAD 4DV7I 3M7NG 5LMUE 3JAMC 2F4VE 4DR2I 1XNRI 4JV5E 2XEXA 2GO3A 4BA2A 4FN5A 2J7KA 3ZZUA 4FWDA 5JEAF 1EI1A 2ZM6E 2UXCE 4DR4E 5LL6R 4DPUA 4NXME 5ELWA 4DR7E 2C38A 3QT5A 4LCGA 1BKNA 3T1YE 4IFDD 4LFBI 4YHHI 4I3HA 3M85D 4UTGA 4JI2E 2HK3A 1KVKA 4U3DA 3PS3A 1DARA 1NZ0A 2F1DA 3J80C 4JI1E 4WUBA 1ZXNA 4DV6E 1N0UA 3K85A 4JV5I 4FW9A 4IFDF 1XMQE 2HKEA 2PO1B 5GMEA 5FLXC 4B3TE 2VQEI 2UXCI 5C0XA 4DR4I 1ZM9A 1FI4A 2BR2B 3QT7A 4DR7I 4NXMI 3PYGA 5DNXA 4X65I 3DD6A 1HNXE 4MQYA 4M1KA 2UU9E 3PYFA 4DPXA 2ZITA 2GO4A 2JE6A 1XXEA 4Z7YA 2V2VA 2BA0D 4GKKE 4DV6I 2PNLA 2C38B 1H7UA 1Z5AA 2C39A 4B3TI 1N36E 1HNWI 1Z0EA 4DV3E 4JI4E 4AIDA 4JI0E 5C0XC 3LTOA 1XHKA 5DRQA 2CZ9A 2IESA 2NPFA 2X36A 1PIEA 2WP8B 2GQ0A 2Z5CB 5DRPA 4LCFA 5DRRA 4BA1A 4DU8A 5A2QC 1FKAE 2Z5BA 3M7ND 4GKKI 4JI8E 4GKJI 2V2ZA 4QNJA 4IS9A 2JEBA 1OJ4A 2E1RA 3P3CA 1Z0CA 4MDTA 1N36I 4KQVA 4YY3E 3B4TA 2JT2A 1S4EA 4FW3A 1MG7A 1Y4UA 1RR9A 1IBLI 4MU1A 1Z5BA 5IT9Q 1A6FA 4DV7E 4WUCA 1H73A 4JI8I 2JEAB 4DR2E 3PS2A 4HACA 4DPWA 4LF4E 2CVEA 3NZKA 1H72C 4DV4I 4OO1C 1N33I 4YY3I 4MYUA 4FW4A 2NN6A 3L7ZB 4X66I 5FWKA 2CG9A 4JI3E 5K36C 2PO0A 3Q6NA 4HYMA 4LOMA 3T1HE 1XNQE 3HKMA 3KRNA 2C37A 2JEBB 4PU9A 1H7SA 3D4JA
chains in the Genus database with same CATH topology
2IERA 4OKGA 3U1YA 3PS2A 4IS9A 2GO3A 3P3EA 4OZEA 3P3GA 3P3CA 4J3DA 4LCHA 4MDTA 5DROA 3NZKA 3PS1A 2JT2A 4FW3A 4FW4A 4LCGA 4FW6A 4FW5A 3P76A 4U3BA 2J65A 1YH8A 4MQYA 2O3ZA 2VESA 5DRQA 2IESA 4FW7A 3UHMA 2GO4A 1P42A 4U3DA 1XXEA 3PS3A 5DRPA 4LCFA 4ISAA 5DRRA 1YHCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IER A;  4OKG A;  3U1Y A;  3PS2 A;  4IS9 A;  2GO3 A;  3P3E A;  4OZE A;  3P3G A;  3P3C A;  4J3D A;  4LCH A;  4MDT A;  5DRO A;  3NZK A;  3PS1 A;  2JT2 A;  4FW3 A;  4FW4 A;  4LCG A;  4FW6 A;  4FW5 A;  3P76 A;  4U3B A;  2J65 A;  1YH8 A;  4MQY A;  2O3Z A;  2VES A;  5DRQ A;  2IES A;  4FW7 A;  3UHM A;  2GO4 A;  1P42 A;  4U3D A;  1XXE A;  3PS3 A;  5DRP A;  4LCF A;  4ISA A;  5DRR A;  1YHC A; 
#chains in the Genus database with same CATH topology
 2GS8 A;  4JI7 E;  3JAM Q;  4X62 E;  1KTV A;  5EKW A;  1RRE A;  4MU3 A;  2WNR A;  4X64 E;  4LF4 I;  2V8P A;  2PO2 A;  4LF7 E;  5DRO A;  4B3R I;  3GON A;  2VQE E;  4AM3 A;  4DUY E;  3J81 Q;  4NBQ A;  4X65 E;  1USV A;  4JI3 I;  1FNM A;  3UHM A;  2HFS A;  2NN6 C;  4JG4 A;  1ZM3 A;  4DU7 A;  3T1H I;  2BA1 G;  1IBM I;  1XNQ I;  2UUA I;  1I94 E;  3Q1Q A;  5IWA I;  1E3H A;  5C0X E;  2BV3 A;  3V2U C;  4JI7 I;  4X62 I;  1E3P A;  4HXZ A;  4X64 I;  3GLL A;  4NXN E;  4J3D A;  1N0V C;  4LF7 I;  1B63 A;  1HNW E;  1MX0 A;  2O1T A;  1HR0 E;  3M6A A;  5FLX Q;  2EFG A;  4DUY I;  3P76 A;  4U3B A;  2C37 B;  5JEA A;  1UDQ A;  1Z0T A;  1N32 I;  4LF6 E;  2WW4 A;  4QNK A;  1UDO A;  1YHC A;  1I94 I;  2BM1 A;  4BA2 B;  4LF8 E;  3B82 A;  2IER A;  2R42 A;  4GKJ E;  3QT6 A;  1KKH A;  4USK A;  4NXN I;  2V2Q A;  2PNM A;  3HUL A;  4DV5 I;  1HR0 I;  4AIM A;  4JI6 E;  4IFD A;  4IZJ A;  4K0K I;  1ZM4 A;  1IBL E;  1H74 A;  3GME A;  1HNZ I;  4LF6 I;  5JEA C;  3OTO I;  4ISA A;  4LFC I;  3V5R A;  4LF8 I;  5A2Q Q;  1OYP A;  5C0X B;  2UXD I;  4OO1 A;  4DR5 E;  1U2R A;  4DPY A;  3HJC A;  4DR1 I;  3CDI A;  2ZBK B;  1UDS A;  2AE8 A;  3K1J A;  4MU0 A;  4DV4 E;  1N33 E;  5K36 A;  2BM0 A;  4JI6 I;  2JE6 B;  4X66 E;  1IBK E;  3B8H A;  4DR3 E;  1NHI A;  4PRX A;  3ZZT A;  2Q2E B;  1NHJ A;  4GQU A;  4IFD C;  5BR8 I;  1MU5 A;  4R1F A;  1Z5C A;  2BA1 D;  4P52 A;  1K47 A;  2C39 B;  5EL9 A;  4PRV A;  2NN6 E;  3ZKD A;  4AQY E;  4DR5 I;  2HK2 A;  3PYD A;  1Y60 A;  4HY1 A;  2O1U A;  4IZJ B;  4B3R E;  3ZM7 A;  1Z0V A;  5IT9 C;  1IBK I;  4DR3 I;  1YH8 A;  4EMD A;  4JI5 E;  2O1W A;  4BA1 B;  4FW7 A;  2Z5B B;  1UDN A;  1PVG A;  4B3S E;  1IBM E;  1ZM2 A;  2UUA E;  4OO1 B;  2CGE A;  4KHP E;  1HK7 A;  2VF3 A;  5IWA E;  3WU3 A;  5K36 B;  3WU6 A;  2Z5E A;  3P3E A;  4AQY I;  2UUB I;  2VQF E;  5C0X D;  1RHY A;  1UEK A;  4JI5 I;  1N34 I;  1FWK A;  2A2C A;  1R6L A;  1XMO I;  2PNZ A;  1FJG E;  4DUZ E;  4OX9 E;  1N32 E;  3PYE A;  4USM A;  4IZK A;  1P42 A;  4B3S I;  4LF5 E;  3B78 A;  4HAC B;  1USU A;  4MYT A;  5C0X F;  4KHP I;  3J80 Q;  2LJP A;  4ED4 A;  3WU5 A;  1D6T A;  3J81 C;  2NN6 B;  5JEA E;  1EA6 A;  2AJ4 A;  2IOP A;  1OYS A;  2PO0 B;  2HFU A;  2VQF I;  4DV0 E;  4DV5 E;  4LFA E;  1WUU A;  4Z7C A;  4UT4 A;  5LMN E;  3U1K A;  2O1V A;  4DV2 E;  4IZJ D;  4RPF A;  4K0K E;  1FJG I;  4DUZ I;  4OX9 I;  1HNZ E;  3ZKB A;  4LF5 I;  5LMU I;  2A2D A;  4XTJ A;  3OTO E;  2E5L E;  4LFC E;  2F4V I;  2WNR B;  3H4L A;  4DV1 E;  2WP8 A;  2PO2 B;  2Z5C A;  4IFD E;  1QZR A;  2UXD E;  2ZM6 I;  4OO1 D;  1ZXM A;  1Y5Y A;  1KIJ A;  3P06 A;  4DR1 E;  1PKP A;  4P7A A;  4DV0 I;  2PNZ B;  4LFA I;  5GMD A;  5K36 D;  4IZK B;  1NHH A;  3T1Y I;  4DR6 E;  5LMN I;  2J65 A;  1Z0G A;  2VES A;  4URL A;  4DV2 I;  4JI2 I;  5BR8 E;  4OO1 F;  4OO1 E;  4JI1 I;  2E5L I;  3ZZ0 A;  2HKJ A;  5K36 F;  4DV1 I;  2DEI A;  1XMQ I;  4N3O A;  5K36 E;  3U1Y A;  2HHH E;  1OYR A;  1B62 A;  2JEA A;  4DPT A;  5JEA B;  4WUD A;  1J5E E;  4FW6 A;  4LF9 E;  1Y6Z A;  1Z0B A;  1HNX I;  3CWV A;  2R3V A;  4DR6 I;  2UU9 I;  2NN6 D;  1FWL A;  3LNU A;  2O3Z A;  3M85 G;  4JYA E;  3L7Z A;  4MU4 A;  4B3M E;  3J7A G;  3CDJ A;  2X7I A;  1Z59 A;  4ZVI A;  3Q6M A;  3K17 A;  4OKG A;  3H1C A;  2NN6 F;  2HHH I;  2DEJ A;  1S16 A;  4IFD B;  2OI2 A;  2UUB E;  2UXB E;  1Z0W A;  3WU4 A;  4DXL A;  4DV3 I;  4JI4 I;  1J5E I;  4JI0 I;  4FW5 A;  4LF9 I;  4LPF A;  2UUC E;  4JYA I;  2IOQ A;  3PRY A;  1N34 E;  1XMO E;  3QT8 A;  2BA0 G;  4B3M I;  3GCM A;  1XNR E;  1VI7 A;  4FWH A;  5L3J A;  2V34 A;  3P3G A;  4OZE A;  4LCH A;  1VIS A;  2UXB I;  3J7A M;  3LPS A;  3PS1 A;  4FWG A;  5DNL A;  2PO1 A;  1Y4S A;  3F0N A;  4LFB E;  2UUC I;  2BR2 A;  4YHH E;  1ELO A;  1R6M A;  5JEA D;  4DV7 I;  3M7N G;  5LMU E;  3JAM C;  2F4V E;  4DR2 I;  1XNR I;  4JV5 E;  2XEX A;  2GO3 A;  4BA2 A;  4FN5 A;  2J7K A;  3ZZU A;  4FWD A;  5JEA F;  1EI1 A;  2ZM6 E;  2UXC E;  4DR4 E;  5LL6 R;  4DPU A;  4NXM E;  5ELW A;  4DR7 E;  2C38 A;  3QT5 A;  4LCG A;  1BKN A;  3T1Y E;  4IFD D;  4LFB I;  4YHH I;  4I3H A;  3M85 D;  4UTG A;  4JI2 E;  2HK3 A;  1KVK A;  4U3D A;  3PS3 A;  1DAR A;  1NZ0 A;  2F1D A;  3J80 C;  4JI1 E;  4WUB A;  1ZXN A;  4DV6 E;  1N0U A;  3K85 A;  4JV5 I;  4FW9 A;  4IFD F;  1XMQ E;  2HKE A;  2PO1 B;  5GME A;  5FLX C;  4B3T E;  2VQE I;  2UXC I;  5C0X A;  4DR4 I;  1ZM9 A;  1FI4 A;  2BR2 B;  3QT7 A;  4DR7 I;  4NXM I;  3PYG A;  5DNX A;  4X65 I;  3DD6 A;  1HNX E;  4MQY A;  4M1K A;  2UU9 E;  3PYF A;  4DPX A;  2ZIT A;  2GO4 A;  2JE6 A;  1XXE A;  4Z7Y A;  2V2V A;  2BA0 D;  4GKK E;  4DV6 I;  2PNL A;  2C38 B;  1H7U A;  1Z5A A;  2C39 A;  4B3T I;  1N36 E;  1HNW I;  1Z0E A;  4DV3 E;  4JI4 E;  4AID A;  4JI0 E;  5C0X C;  3LTO A;  1XHK A;  5DRQ A;  2CZ9 A;  2IES A;  2NPF A;  2X36 A;  1PIE A;  2WP8 B;  2GQ0 A;  2Z5C B;  5DRP A;  4LCF A;  5DRR A;  4BA1 A;  4DU8 A;  5A2Q C;  1FKA E;  2Z5B A;  3M7N D;  4GKK I;  4JI8 E;  4GKJ I;  2V2Z A;  4QNJ A;  4IS9 A;  2JEB A;  1OJ4 A;  2E1R A;  3P3C A;  1Z0C A;  4MDT A;  1N36 I;  4KQV A;  4YY3 E;  3B4T A;  2JT2 A;  1S4E A;  4FW3 A;  1MG7 A;  1Y4U A;  1RR9 A;  1IBL I;  4MU1 A;  1Z5B A;  5IT9 Q;  1A6F A;  4DV7 E;  4WUC A;  1H73 A;  4JI8 I;  2JEA B;  4DR2 E;  3PS2 A;  4HAC A;  4DPW A;  4LF4 E;  2CVE A;  3NZK A;  1H72 C;  4DV4 I;  4OO1 C;  1N33 I;  4YY3 I;  4MYU A;  4FW4 A;  2NN6 A;  3L7Z B;  4X66 I;  5FWK A;  2CG9 A;  4JI3 E;  5K36 C;  2PO0 A;  3Q6N A;  4HYM A;  4LOM A;  3T1H E;  1XNQ E;  3HKM A;  3KRN A;  2C37 A;  2JEB B;  4PU9 A;  1H7S A;  3D4J A; 
#chains in the Genus database with same CATH homology
 2IER A;  4OKG A;  3U1Y A;  3PS2 A;  4IS9 A;  2GO3 A;  3P3E A;  4OZE A;  3P3G A;  3P3C A;  4J3D A;  4LCH A;  4MDT A;  5DRO A;  3NZK A;  3PS1 A;  2JT2 A;  4FW3 A;  4FW4 A;  4LCG A;  4FW6 A;  4FW5 A;  3P76 A;  4U3B A;  2J65 A;  1YH8 A;  4MQY A;  2O3Z A;  2VES A;  5DRQ A;  2IES A;  4FW7 A;  3UHM A;  2GO4 A;  1P42 A;  4U3D A;  1XXE A;  3PS3 A;  5DRP A;  4LCF A;  4ISA A;  5DRR A;  1YHC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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