4MU1A

The structure of wt a. thaliana igpd2 in complex with mn2+, imidazole, and sulfate at 1.5 a resolution
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
185
structure length
184
Chain Sequence
SARIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLAHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
molecule tags Lyase
source organism Arabidopsis thaliana
molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
total genus 54
structure length 184
sequence length 185
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2013-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu1A01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu1A02
4QNKA 2F1DA 4LPFA 5ELWA 5EKWA 5DNLA 4LOMA 4GQUA 5DNXA 4QNJA 4MU3A 1RHYA 2AE8A 5EL9A 4MU1A 4MU4A 4MU0A
chains in the Genus database with same CATH superfamily
1N34I 2UUBE 2UUBI 1Z0EA 3T1HE 2V2ZA 5EL9A 4B3RI 1YH8A 5K36A 4IFDD 2PO0A 4J3DA 2Z5BA 4MU3A 4X62E 1HNZI 2V2QA 4DV4E 3Q6MA 4DR6I 2WP8B 1A6FA 2NN6D 3L7ZB 1DARA 3ZZ0A 2AJ4A 1ZXNA 4JI4E 2BR2A 1Z0CA 2O1TA 2UXDE 2UXDI 2XEXA 2BM0A 1H7UA 3GMEA 2F4VE 1FNMA 4JV5I 1FWKA 5L3JA 4AQYE 4AQYI 1UDNA 1N33E 1Z5BA 4JI0I 3CDIA 4OZEA 2IOPA 1J5EE 4LCHA 2WW4A 4IFDE 4OKGA 2E1RA 2VQEI 4BA2B 3M7NG 3ZZUA 1HK7A 1Z0WA 2NN6E 4IFDF 4IFDA 4X66E 4LCFA 4DPTA 4X66I 4DR2I 4DR2E 2JEAA 1USUA 5DROA 3ZM7A 3PYFA 3D4JA 4EMDA 2NN6F 2NN6A 4IZJB 4LF6E 3GLLA 4LF6I 1Z59A 1Y60A 4GKJE 5A2QQ 1EI1A 1RREA 4AIMA 4HACB 4FWDA 5BR8E 2VQFI 4OX9E 4NXNI 1XMQI 1Z5AA 5JEAB 1HNWI 3T1YI 3HULA 1KTVA 2PO1A 4WUCA 4DV5I 5JEAC 1H7SA 1QZRA 4Z7YA 2UU9I 3J80Q 2C38A 5IT9C 4OO1C 4FW9A 3ZKDA 4FWHA 1NHHA 4MU0A 1VI7A 5FWKA 4DV2E 5C0XD 5IWAE 1MX0A 5FLXQ 1HR0E 1N32E 4B3TI 4XTJA 2BA0D 2CZ9A 2UUCI 4NXME 4NXMI 4KQVA 3PRYA 4JG4A 4MDTA 5K36D 3B78A 1USVA 5EKWA 3H4LA 3DD6A 4LFCE 1KVKA 1XNQE 1FI4A 4JI8E 2JE6B 4JI8I 4JI2E 3P06A 1IBKE 5C0XE 4JI7I 4DR7E 4DR7I 3J7AM 2PNZA 4FW5A 1RHYA 1XXEA 1KIJA 4AIDA 4DV3I 4DR3I 5C0XF 3ZKBA 2O1UA 3K17A 2GQ0A 2Q2EB 3WU5A 5K36E 2HFSA 4KHPE 1E3PA 5DRPA 1N34E 3U1YA 4PRXA 1H74A 2E5LI 4NBQA 4B3RE 5DRQA 2F1DA 5K36F 4LOMA 2HK2A 2WP8A 1HNZE 1FJGE 1FJGI 5A2QC 4DR1I 1I94I 4DR6E 4B3MI 1UDQA 4JI6I 4GKKI 3OTOI 3CWVA 1R6MA 2WNRB 2DEIA 2AE8A 1IBMI 2X7IA 4JV5E 4DUZE 4U3BA 4DUZI 2BM1A 4JI0E 2PO2B 1ZM3A 2PO0B 2Z5BB 2PNMA 4LF7I 2VQEE 3M7ND 2VESA 4PU9A 4I3HA 3PS2A 4WUDA 5LMNE 5LMNI 4FWGA 4RPFA 2HKEA 1Z0BA 3F0NA 2BR2B 4P52A 4IZKA 4HXZA 4IZJA 4YY3I 1Y4SA 1OYSA 2C39B 5LMUI 1ELOA 2GS8A 3JAMQ 1FKAE 4FW7A 4LFBI 3B4TA 4JI1I 5GMDA 4DUYI 2Z5CA 5DRRA 3J7AG 1ZM2A 2PNLA 3LPSA 2VQFE 5JEAA 4NXNE 3Q1QA 1B63A 1XMQE 3P3EA 2HK3A 4K0KI 1NHIA 1HNWE 3T1YE 2J65A 2ZBKB 4IFDB 4OO1A 4OO1F 2ZITA 3V5RA 4DV5E 1K47A 2VF3A 1Z0TA 2UUAI 4BA1A 2UU9E 5DNLA 2NN6B 4M1KA 4IFDC 3K1JA 3M85G 1E3HA 1YHCA 4FW3A 3UHMA 4R1FA 2NN6C 3GONA 1PKPA 1P42A 2BV3A 4B3TE 4QNJA 4DV1I 2IESA 1ZXMA 2NPFA 4DXLA 2UUCE 1XNRI 1UDSA 4UTGA 5DNXA 4USMA 2JEBA 4YHHE 4YHHI 4FW4A 1OYRA 2UXBE 2UXBI 4ZVIA 1N36I 2C37A 2C38B 3Q6NA 1HNXI 4MQYA 2JE6A 2IERA 1MG7A 4LF8I 2GO3A 4Z7CA 4LFAI 2BA1G 1S4EA 1UDOA 4HY1A 2ZM6I 4DU7A 2OI2A 4JI7E 3P76A 4DV0I 1ZM9A 4LF5I 4MU1A 4JI3E 4JI3I 4DV3E 4P7AA 4DR3E 2CVEA 2CG9A 3QT6A 2HHHI 4X64I 2UXCI 1EA6A 1S16A 3U1KA 2E5LE 1KKHA 4B3SI 1OYPA 4JYAI 3ZZTA 1XMOI 4DV6E 4DV6I 3JAMC 4N3OA 4IZJD 3L7ZA 3PS1A 4DR1E 2HFUA 4GQUA 1I94E 4B3ME 2PNZB 3B82A 4LF9I 4JI6E 1PIEA 4X65E 4X65I 5C0XB 3OTOE 4GKKE 4DV7I 4JI5I 1IBME 1H73A 2CGEA 4FW6A 4MYTA 5JEAD 3T1HI 1XHKA 5C0XC 1Y5YA 1U2RA 4LCGA 2PO2A 4URLA 4X62I 5K36B 1B62A 1Y6ZA 4OO1D 4BA2A 4DV4I 3J80C 4LF7E 4U3DA 4ISAA 4PRVA 1MU5A 5K36C 4HYMA 4UT4A 2IOQA 1H72C 4WUBA 3QT7A 4JI4I 4LF4E 4LF4I 2LJPA 5FLXC 1IBLE 1IBLI 2C39A 4YY3E 2EFGA 4FN5A 2F4VI 2V34A 3J81Q 3M6AA 5LMUE 5JEAE 3HKMA 4LFBE 1N33I 1J5EI 4HACA 1OJ4A 4DR4E 4DR4I 3CDJA 4JI1E 4DUYE 5JEAF 4OO1E 1Z0VA 3PYEA 3H1CA 1BKNA 1Z0GA 4K0KE 4IS9A 4DR5E 4DR5I 4MU4A 4ED4A 2O1VA 4DPXA 4AM3A 2JEAB 3LNUA 4IZKB 4LPFA 2UUAE 4GKJI 3M85D 2O3ZA 4DU8A 5BR8I 3WU6A 1RR9A 4OX9I 1D6TA 2Z5CB 3PYDA 4USKA 2A2CA 5LL6R 3B8HA 3PS3A 2HKJA 4DV1E 3QT8A 1XNRE 3HJCA 4OO1B 3P3CA 2PO1B 1N0UA 3LTOA 2Z5EA 4QNKA 3K85A 4BA1B 2A2DA 3V2UC 4DPUA 2O1WA 1N36E 1UEKA 1HNXE 5ELWA 1PVGA 2X36A 4DV2I 2GO4A 2JT2A 1NHJA 2R42A 2J7KA 5IWAI 4LF8E 1HR0I 2BA1D 4LFAE 2ZM6E 3KRNA 1N32I 1ZM4A 2BA0G 4DV0E 2V8PA 2V2VA 4LF5E 2R3VA 3WU4A 1N0VC 3NZKA 1Y4UA 2JEBB 3P3GA 2HHHE 4X64E 2UXCE 1WUUA 4LFCI 4DPWA 3GCMA 1XNQI 4MYUA 1R6LA 2C37B 1Z5CA 1VISA 4B3SE 4JI2I 5GMEA 4JYAE 1IBKI 3J81C 3QT5A 1XMOE 4DPYA 1NZ0A 3WU3A 3PYGA 2DEJA 5C0XA 4LF9E 5IT9Q 2WNRA 1FWLA 4DV7E 4JI5E 4KHPI
chains in the Genus database with same CATH topology
4QNKA 2F1DA 4LPFA 5ELWA 5EKWA 5DNLA 4LOMA 4GQUA 5DNXA 4QNJA 4MU3A 1RHYA 2AE8A 5EL9A 4MU1A 4MU4A 4MU0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QNK A;  2F1D A;  4LPF A;  5ELW A;  5EKW A;  5DNL A;  4LOM A;  4GQU A;  5DNX A;  4QNJ A;  4MU3 A;  1RHY A;  2AE8 A;  5EL9 A;  4MU1 A;  4MU4 A;  4MU0 A; 
#chains in the Genus database with same CATH topology
 1N34 I;  2UUB E;  2UUB I;  1Z0E A;  3T1H E;  2V2Z A;  5EL9 A;  4B3R I;  1YH8 A;  5K36 A;  4IFD D;  2PO0 A;  4J3D A;  2Z5B A;  4MU3 A;  4X62 E;  1HNZ I;  2V2Q A;  4DV4 E;  3Q6M A;  4DR6 I;  2WP8 B;  1A6F A;  2NN6 D;  3L7Z B;  1DAR A;  3ZZ0 A;  2AJ4 A;  1ZXN A;  4JI4 E;  2BR2 A;  1Z0C A;  2O1T A;  2UXD E;  2UXD I;  2XEX A;  2BM0 A;  1H7U A;  3GME A;  2F4V E;  1FNM A;  4JV5 I;  1FWK A;  5L3J A;  4AQY E;  4AQY I;  1UDN A;  1N33 E;  1Z5B A;  4JI0 I;  3CDI A;  4OZE A;  2IOP A;  1J5E E;  4LCH A;  2WW4 A;  4IFD E;  4OKG A;  2E1R A;  2VQE I;  4BA2 B;  3M7N G;  3ZZU A;  1HK7 A;  1Z0W A;  2NN6 E;  4IFD F;  4IFD A;  4X66 E;  4LCF A;  4DPT A;  4X66 I;  4DR2 I;  4DR2 E;  2JEA A;  1USU A;  5DRO A;  3ZM7 A;  3PYF A;  3D4J A;  4EMD A;  2NN6 F;  2NN6 A;  4IZJ B;  4LF6 E;  3GLL A;  4LF6 I;  1Z59 A;  1Y60 A;  4GKJ E;  5A2Q Q;  1EI1 A;  1RRE A;  4AIM A;  4HAC B;  4FWD A;  5BR8 E;  2VQF I;  4OX9 E;  4NXN I;  1XMQ I;  1Z5A A;  5JEA B;  1HNW I;  3T1Y I;  3HUL A;  1KTV A;  2PO1 A;  4WUC A;  4DV5 I;  5JEA C;  1H7S A;  1QZR A;  4Z7Y A;  2UU9 I;  3J80 Q;  2C38 A;  5IT9 C;  4OO1 C;  4FW9 A;  3ZKD A;  4FWH A;  1NHH A;  4MU0 A;  1VI7 A;  5FWK A;  4DV2 E;  5C0X D;  5IWA E;  1MX0 A;  5FLX Q;  1HR0 E;  1N32 E;  4B3T I;  4XTJ A;  2BA0 D;  2CZ9 A;  2UUC I;  4NXM E;  4NXM I;  4KQV A;  3PRY A;  4JG4 A;  4MDT A;  5K36 D;  3B78 A;  1USV A;  5EKW A;  3H4L A;  3DD6 A;  4LFC E;  1KVK A;  1XNQ E;  1FI4 A;  4JI8 E;  2JE6 B;  4JI8 I;  4JI2 E;  3P06 A;  1IBK E;  5C0X E;  4JI7 I;  4DR7 E;  4DR7 I;  3J7A M;  2PNZ A;  4FW5 A;  1RHY A;  1XXE A;  1KIJ A;  4AID A;  4DV3 I;  4DR3 I;  5C0X F;  3ZKB A;  2O1U A;  3K17 A;  2GQ0 A;  2Q2E B;  3WU5 A;  5K36 E;  2HFS A;  4KHP E;  1E3P A;  5DRP A;  1N34 E;  3U1Y A;  4PRX A;  1H74 A;  2E5L I;  4NBQ A;  4B3R E;  5DRQ A;  2F1D A;  5K36 F;  4LOM A;  2HK2 A;  2WP8 A;  1HNZ E;  1FJG E;  1FJG I;  5A2Q C;  4DR1 I;  1I94 I;  4DR6 E;  4B3M I;  1UDQ A;  4JI6 I;  4GKK I;  3OTO I;  3CWV A;  1R6M A;  2WNR B;  2DEI A;  2AE8 A;  1IBM I;  2X7I A;  4JV5 E;  4DUZ E;  4U3B A;  4DUZ I;  2BM1 A;  4JI0 E;  2PO2 B;  1ZM3 A;  2PO0 B;  2Z5B B;  2PNM A;  4LF7 I;  2VQE E;  3M7N D;  2VES A;  4PU9 A;  4I3H A;  3PS2 A;  4WUD A;  5LMN E;  5LMN I;  4FWG A;  4RPF A;  2HKE A;  1Z0B A;  3F0N A;  2BR2 B;  4P52 A;  4IZK A;  4HXZ A;  4IZJ A;  4YY3 I;  1Y4S A;  1OYS A;  2C39 B;  5LMU I;  1ELO A;  2GS8 A;  3JAM Q;  1FKA E;  4FW7 A;  4LFB I;  3B4T A;  4JI1 I;  5GMD A;  4DUY I;  2Z5C A;  5DRR A;  3J7A G;  1ZM2 A;  2PNL A;  3LPS A;  2VQF E;  5JEA A;  4NXN E;  3Q1Q A;  1B63 A;  1XMQ E;  3P3E A;  2HK3 A;  4K0K I;  1NHI A;  1HNW E;  3T1Y E;  2J65 A;  2ZBK B;  4IFD B;  4OO1 A;  4OO1 F;  2ZIT A;  3V5R A;  4DV5 E;  1K47 A;  2VF3 A;  1Z0T A;  2UUA I;  4BA1 A;  2UU9 E;  5DNL A;  2NN6 B;  4M1K A;  4IFD C;  3K1J A;  3M85 G;  1E3H A;  1YHC A;  4FW3 A;  3UHM A;  4R1F A;  2NN6 C;  3GON A;  1PKP A;  1P42 A;  2BV3 A;  4B3T E;  4QNJ A;  4DV1 I;  2IES A;  1ZXM A;  2NPF A;  4DXL A;  2UUC E;  1XNR I;  1UDS A;  4UTG A;  5DNX A;  4USM A;  2JEB A;  4YHH E;  4YHH I;  4FW4 A;  1OYR A;  2UXB E;  2UXB I;  4ZVI A;  1N36 I;  2C37 A;  2C38 B;  3Q6N A;  1HNX I;  4MQY A;  2JE6 A;  2IER A;  1MG7 A;  4LF8 I;  2GO3 A;  4Z7C A;  4LFA I;  2BA1 G;  1S4E A;  1UDO A;  4HY1 A;  2ZM6 I;  4DU7 A;  2OI2 A;  4JI7 E;  3P76 A;  4DV0 I;  1ZM9 A;  4LF5 I;  4MU1 A;  4JI3 E;  4JI3 I;  4DV3 E;  4P7A A;  4DR3 E;  2CVE A;  2CG9 A;  3QT6 A;  2HHH I;  4X64 I;  2UXC I;  1EA6 A;  1S16 A;  3U1K A;  2E5L E;  1KKH A;  4B3S I;  1OYP A;  4JYA I;  3ZZT A;  1XMO I;  4DV6 E;  4DV6 I;  3JAM C;  4N3O A;  4IZJ D;  3L7Z A;  3PS1 A;  4DR1 E;  2HFU A;  4GQU A;  1I94 E;  4B3M E;  2PNZ B;  3B82 A;  4LF9 I;  4JI6 E;  1PIE A;  4X65 E;  4X65 I;  5C0X B;  3OTO E;  4GKK E;  4DV7 I;  4JI5 I;  1IBM E;  1H73 A;  2CGE A;  4FW6 A;  4MYT A;  5JEA D;  3T1H I;  1XHK A;  5C0X C;  1Y5Y A;  1U2R A;  4LCG A;  2PO2 A;  4URL A;  4X62 I;  5K36 B;  1B62 A;  1Y6Z A;  4OO1 D;  4BA2 A;  4DV4 I;  3J80 C;  4LF7 E;  4U3D A;  4ISA A;  4PRV A;  1MU5 A;  5K36 C;  4HYM A;  4UT4 A;  2IOQ A;  1H72 C;  4WUB A;  3QT7 A;  4JI4 I;  4LF4 E;  4LF4 I;  2LJP A;  5FLX C;  1IBL E;  1IBL I;  2C39 A;  4YY3 E;  2EFG A;  4FN5 A;  2F4V I;  2V34 A;  3J81 Q;  3M6A A;  5LMU E;  5JEA E;  3HKM A;  4LFB E;  1N33 I;  1J5E I;  4HAC A;  1OJ4 A;  4DR4 E;  4DR4 I;  3CDJ A;  4JI1 E;  4DUY E;  5JEA F;  4OO1 E;  1Z0V A;  3PYE A;  3H1C A;  1BKN A;  1Z0G A;  4K0K E;  4IS9 A;  4DR5 E;  4DR5 I;  4MU4 A;  4ED4 A;  2O1V A;  4DPX A;  4AM3 A;  2JEA B;  3LNU A;  4IZK B;  4LPF A;  2UUA E;  4GKJ I;  3M85 D;  2O3Z A;  4DU8 A;  5BR8 I;  3WU6 A;  1RR9 A;  4OX9 I;  1D6T A;  2Z5C B;  3PYD A;  4USK A;  2A2C A;  5LL6 R;  3B8H A;  3PS3 A;  2HKJ A;  4DV1 E;  3QT8 A;  1XNR E;  3HJC A;  4OO1 B;  3P3C A;  2PO1 B;  1N0U A;  3LTO A;  2Z5E A;  4QNK A;  3K85 A;  4BA1 B;  2A2D A;  3V2U C;  4DPU A;  2O1W A;  1N36 E;  1UEK A;  1HNX E;  5ELW A;  1PVG A;  2X36 A;  4DV2 I;  2GO4 A;  2JT2 A;  1NHJ A;  2R42 A;  2J7K A;  5IWA I;  4LF8 E;  1HR0 I;  2BA1 D;  4LFA E;  2ZM6 E;  3KRN A;  1N32 I;  1ZM4 A;  2BA0 G;  4DV0 E;  2V8P A;  2V2V A;  4LF5 E;  2R3V A;  3WU4 A;  1N0V C;  3NZK A;  1Y4U A;  2JEB B;  3P3G A;  2HHH E;  4X64 E;  2UXC E;  1WUU A;  4LFC I;  4DPW A;  3GCM A;  1XNQ I;  4MYU A;  1R6L A;  2C37 B;  1Z5C A;  1VIS A;  4B3S E;  4JI2 I;  5GME A;  4JYA E;  1IBK I;  3J81 C;  3QT5 A;  1XMO E;  4DPY A;  1NZ0 A;  3WU3 A;  3PYG A;  2DEJ A;  5C0X A;  4LF9 E;  5IT9 Q;  2WNR A;  1FWL A;  4DV7 E;  4JI5 E;  4KHP I; 
#chains in the Genus database with same CATH homology
 4QNK A;  2F1D A;  4LPF A;  5ELW A;  5EKW A;  5DNL A;  4LOM A;  4GQU A;  5DNX A;  4QNJ A;  4MU3 A;  1RHY A;  2AE8 A;  5EL9 A;  4MU1 A;  4MU4 A;  4MU0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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