4OKGA

Lpxc from p.aeruginosa with the inhibitor 6-(benzimidazol-1-yl)-5-[4-[2-[6-[(4-methylpiperazin-1-yl)methyl]-3-pyridyl]ethynyl]phenyl]pyridine-3-carbohydroxamic acid
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
299
structure length
299
Chain Sequence
MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Overexpression of Pseudomonas aeruginosa LpxC in the Presence of an Inhibitor in an acrB Deletion Escherichia coli strain for Structural Studies
rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Pseudomonas aeruginosa
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 88
structure length 299
sequence length 299
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2014-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4okgA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4okgA02
4OZEA 3P3EA 2GO3A 4FW4A 3PS3A 4FW3A 3PS2A 1XXEA 5DROA 4ISAA 4FW5A 2JT2A 3UHMA 4IS9A 3U1YA 4MQYA 3NZKA 3P3CA 5DRQA 1YH8A 5DRPA 3P76A 4U3BA 4J3DA 2O3ZA 4LCHA 5DRRA 2J65A 3P3GA 1P42A 4OKGA 4FW7A 4MDTA 2VESA 4LCFA 2IERA 4LCGA 1YHCA 2GO4A 4FW6A 2IESA 3PS1A 4U3DA
chains in the Genus database with same CATH superfamily
4AIDA 4OZEA 1NZ0A 5EKWA 2Z5EA 4USKA 4R1FA 2BR2A 4FW3A 2NN6D 5DROA 5FWKA 4QNKA 4JI4I 2X36A 2JT2A 3K1JA 1NHJA 4IZJA 1KIJA 4DV4I 4JI2E 1RHYA 3HJCA 1IBLE 4OO1F 1OYRA 1MU5A 1MG7A 3P3GA 4AQYE 1H73A 1YHCA 1RREA 4QNJA 1EA6A 4BA1A 2PO1A 2JEAB 3B4TA 2C38B 4URLA 4DR3E 5FLXQ 4HXZA 4JI0E 2ZM6I 1MX0A 1HNZE 4X66I 3U1KA 4DR4E 1FWKA 4K0KI 4DR6E 4OO1C 5C0XB 2PO0A 3J7AM 3V2UC 2WP8A 4HYMA 4KHPI 4JI7I 4DV2I 2AJ4A 5JEAD 1UDSA 1IBMI 1FJGE 2BR2B 5LMUE 2PNLA 2UUAI 4DPTA 3DD6A 4DV6E 3P3EA 5C0XD 3WU5A 1J5EE 4LF9I 1KKHA 1A6FA 1IBKI 5IWAI 4FN5A 4LF5E 4BA2B 3Q6NA 2O1VA 2VQEE 3J81Q 4FW7A 4BA1B 2PO1B 4IZJD 1Y4UA 4FWGA 4RPFA 2A2CA 5K36F 3ZKDA 2E5LE 4WUCA 1S16A 2O1UA 4LFAE 3J7AG 2VQFE 1XMOI 1EI1A 1KTVA 4MU0A 1DARA 4I3HA 2JE6B 5GMDA 2WP8B 1Z0EA 4LFCI 4AIMA 4IFDF 5BR8E 1FI4A 5DRPA 3OTOI 1B62A 2F4VE 4PU9A 2CZ9A 4JYAI 4HACA 1U2RA 4DV1E 5LMNE 4JI1E 1UDOA 4PRXA 1XNRE 3GMEA 1HK7A 5K36C 3M85D 4Z7YA 4B3SI 2EFGA 4PRVA 2BM0A 4NXNI 3PS3A 4NXME 2NN6C 2UUBI 3JAMC 5IT9C 4OO1E 4IFDC 2GQ0A 4MU1A 4LF4E 1S4EA 4J3DA 4LCHA 2UU9I 1H7SA 4OKGA 2Q2EB 4XTJA 1E3PA 1NHHA 2VESA 3ZZUA 2UUCE 2BA0D 5DNLA 5L3JA 4YHHE 4JI6E 3T1YE 1UDNA 1N32I 3QT8A 4GQUA 4JI3I 4GKJE 2XEXA 2GS8A 2BA1G 2Z5CA 4DU8A 4JV5I 4DV7I 1OYPA 4HACB 1K47A 1ZM4A 1Z0WA 3U1YA 1XHKA 4MQYA 4JI8I 1HR0E 3LNUA 4DPXA 1N33I 1OYSA 3T1HI 4DR7I 1FNMA 2GO4A 3LTOA 2IOQA 1XNQE 4BA2A 1I94E 1N36E 4DV0I 4HY1A 3L7ZA 2HFUA 2HHHI 1USUA 3D4JA 4WUBA 1R6LA 4FW4A 4B3ME 2PNZA 4MYTA 4OO1A 4DV3I 2JEBA 4FW5A 4Z7CA 3M7NG 3WU6A 1ZM3A 2WNRA 2Z5BB 5DRQA 1PIEA 4U3BA 3WU4A 4DR5E 2J65A 4DR1I 2V2VA 2R3VA 4LF6E 1N34I 4OX9E 2JE6A 4LFBI 4DR2E 4EMDA 5K36E 4YY3I 2Z5CB 4X65E 4LF8I 4NBQA 4DV5E 3ZKBA 2HK3A 3CDJA 4IZKA 2PNMA 4IFDE 4M1KA 5A2QC 2A2DA 4B3RE 5GMEA 2PO2B 3UHMA 3JAMQ 2UXCE 5IT9Q 1FWLA 1OJ4A 4JI2I 3P3CA 1IBLI 3QT5A 2WW4A 4AQYI 1P42A 4DUZE 3L7ZB 1HNWE 2HK2A 1Y5YA 3PS1A 4DUYE 1PVGA 1HNXE 2PNZB 1H7UA 4OO1B 4MU3A 1WUUA 2JEBB 1ZXNA 4X64E 2WNRB 4DR3I 4B3TE 4JI0I 4USMA 2NN6F 4LF7E 1ZM2A 4IS9A 1HNZI 1VISA 1RR9A 4DR4I 4OO1D 2V8PA 2F1DA 1UEKA 4DXLA 4DR6I 2C37A 2IOPA 1XMQE 5K36A 2DEIA 4MU4A 4JI5I 4GKKE 2UXDE 1FJGI 3ZZ0A 2BV3A 5LMUI 4IZKB 3PRYA 2UXBE 4FWDA 4DV6I 2R42A 2O1TA 4IFDA 1Y4SA 3J80C 1Z5BA 4FW9A 1Z0GA 1J5EI 4ZVIA 4JI4E 4LF5I 2VQEI 2O3ZA 4DV4E 3M85G 3M6AA 5ELWA 1QZRA 2Z5BA 2E5LI 3LPSA 5JEAF 2OI2A 2NPFA 4LFAI 2VQFI 3KRNA 4X62I 2C37B 5C0XF 5K36B 5BR8I 2BA1D 2VF3A 3QT6A 2ZM6E 2F4VI 3ZM7A 4X66E 4DV1I 4WUDA 4K0KE 4JI1I 5LMNI 2NN6B 3V5RA 4LCFA 2DEJA 2AE8A 2PO2A 4IFDB 4KHPE 3K85A 1XNRI 2IESA 3P06A 4JI7E 4U3DA 4DV2E 5K36D 3WU3A 1IBME 5JEAC 3PYFA 4DPWA 2UUAE 2ZBKB 4DPYA 3F0NA 4NXMI 3H1CA 1XXEA 5C0XC 2O1WA 4IFDD 1USVA 1Z0CA 4LF9E 2E1RA 2LJPA 4LF4I 1YH8A 1Y6ZA 3HULA 1IBKE 2V2QA 5IWAE 1VI7A 3M7ND 2J7KA 2UUCI 1Z59A 1H72C 4FW6A 4JI6I 4YHHI 3T1YI 1UDQA 1B63A 3HKMA 3QT7A 4GKJI 1XMOE 2GO3A 3J80Q 2NN6E 4FWHA 5JEAB 2CVEA 4DU7A 4LFCE 1Z0TA 1HR0I 3P76A 3OTOE 3B8HA 5DNXA 1Y60A 4JYAE 2X7IA 3GONA 4JI5E 1D6TA 3B82A 4UTGA 1XNQI 1I94I 1N36I 3CDIA 3ZZTA 2CG9A 4IZJB 4B3SE 4B3MI 1ZM9A 2CGEA 3K17A 4NXNE 3PS2A 2BM1A 2HFSA 4DPUA 2UUBE 3NZKA 4DR5I 5DRRA 3GLLA 3PYGA 4LF6I 2UU9E 4MYUA 4OX9I 4DR2I 3CWVA 1H74A 4X65I 5JEAE 1Z5AA 1Z0BA 4DV5I 1FKAE 1N32E 4P7AA 2NN6A 3PYEA 4JI3E 5C0XE 4X62E 3PYDA 5FLXC 4JV5E 4DV7E 2PO0B 4B3RI 2UXCI 2C39A 1KVKA 1PKPA 1Z0VA 4JI8E 4UT4A 1E3HA 4DUZI 3GCMA 4MDTA 1HNWI 5LL6R 2HKEA 1N33E 1ZXMA 2IERA 4LCGA 3T1HE 1HNXI 4DUYI 4DR7E 2ZITA 3Q1QA 4X64I 4DV0E 1ELOA 4N3OA 2V2ZA 2HHHE 4JG4A 1Z5CA 4P52A 4B3TI 4DV3E 4LF7I 2JEAA 4ISAA 2C38A 1R6MA 5A2QQ 1NHIA 1N0UA 5EL9A 2BA0G 3B78A 1XMQI 1N0VC 2V34A 3J81C 4DR1E 5JEAA 4GKKI 2UXDI 3H4LA 3Q6MA 1N34E 4LFBE 2HKJA 4AM3A 4YY3E 2UXBI 4LOMA 5C0XA 4LF8E 4KQVA 4LPFA 1BKNA 2C39B 4ED4A
chains in the Genus database with same CATH topology
4OZEA 3P3EA 2GO3A 4FW4A 3PS3A 4FW3A 3PS2A 1XXEA 5DROA 4ISAA 4FW5A 2JT2A 3UHMA 4IS9A 3U1YA 4MQYA 3NZKA 3P3CA 5DRQA 1YH8A 5DRPA 3P76A 4U3BA 4J3DA 2O3ZA 4LCHA 5DRRA 2J65A 3P3GA 1P42A 4OKGA 4FW7A 4MDTA 2VESA 4LCFA 2IERA 4LCGA 1YHCA 2GO4A 4FW6A 2IESA 3PS1A 4U3DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OZE A;  3P3E A;  2GO3 A;  4FW4 A;  3PS3 A;  4FW3 A;  3PS2 A;  1XXE A;  5DRO A;  4ISA A;  4FW5 A;  2JT2 A;  3UHM A;  4IS9 A;  3U1Y A;  4MQY A;  3NZK A;  3P3C A;  5DRQ A;  1YH8 A;  5DRP A;  3P76 A;  4U3B A;  4J3D A;  2O3Z A;  4LCH A;  5DRR A;  2J65 A;  3P3G A;  1P42 A;  4OKG A;  4FW7 A;  4MDT A;  2VES A;  4LCF A;  2IER A;  4LCG A;  1YHC A;  2GO4 A;  4FW6 A;  2IES A;  3PS1 A;  4U3D A; 
#chains in the Genus database with same CATH topology
 4AID A;  4OZE A;  1NZ0 A;  5EKW A;  2Z5E A;  4USK A;  4R1F A;  2BR2 A;  4FW3 A;  2NN6 D;  5DRO A;  5FWK A;  4QNK A;  4JI4 I;  2X36 A;  2JT2 A;  3K1J A;  1NHJ A;  4IZJ A;  1KIJ A;  4DV4 I;  4JI2 E;  1RHY A;  3HJC A;  1IBL E;  4OO1 F;  1OYR A;  1MU5 A;  1MG7 A;  3P3G A;  4AQY E;  1H73 A;  1YHC A;  1RRE A;  4QNJ A;  1EA6 A;  4BA1 A;  2PO1 A;  2JEA B;  3B4T A;  2C38 B;  4URL A;  4DR3 E;  5FLX Q;  4HXZ A;  4JI0 E;  2ZM6 I;  1MX0 A;  1HNZ E;  4X66 I;  3U1K A;  4DR4 E;  1FWK A;  4K0K I;  4DR6 E;  4OO1 C;  5C0X B;  2PO0 A;  3J7A M;  3V2U C;  2WP8 A;  4HYM A;  4KHP I;  4JI7 I;  4DV2 I;  2AJ4 A;  5JEA D;  1UDS A;  1IBM I;  1FJG E;  2BR2 B;  5LMU E;  2PNL A;  2UUA I;  4DPT A;  3DD6 A;  4DV6 E;  3P3E A;  5C0X D;  3WU5 A;  1J5E E;  4LF9 I;  1KKH A;  1A6F A;  1IBK I;  5IWA I;  4FN5 A;  4LF5 E;  4BA2 B;  3Q6N A;  2O1V A;  2VQE E;  3J81 Q;  4FW7 A;  4BA1 B;  2PO1 B;  4IZJ D;  1Y4U A;  4FWG A;  4RPF A;  2A2C A;  5K36 F;  3ZKD A;  2E5L E;  4WUC A;  1S16 A;  2O1U A;  4LFA E;  3J7A G;  2VQF E;  1XMO I;  1EI1 A;  1KTV A;  4MU0 A;  1DAR A;  4I3H A;  2JE6 B;  5GMD A;  2WP8 B;  1Z0E A;  4LFC I;  4AIM A;  4IFD F;  5BR8 E;  1FI4 A;  5DRP A;  3OTO I;  1B62 A;  2F4V E;  4PU9 A;  2CZ9 A;  4JYA I;  4HAC A;  1U2R A;  4DV1 E;  5LMN E;  4JI1 E;  1UDO A;  4PRX A;  1XNR E;  3GME A;  1HK7 A;  5K36 C;  3M85 D;  4Z7Y A;  4B3S I;  2EFG A;  4PRV A;  2BM0 A;  4NXN I;  3PS3 A;  4NXM E;  2NN6 C;  2UUB I;  3JAM C;  5IT9 C;  4OO1 E;  4IFD C;  2GQ0 A;  4MU1 A;  4LF4 E;  1S4E A;  4J3D A;  4LCH A;  2UU9 I;  1H7S A;  4OKG A;  2Q2E B;  4XTJ A;  1E3P A;  1NHH A;  2VES A;  3ZZU A;  2UUC E;  2BA0 D;  5DNL A;  5L3J A;  4YHH E;  4JI6 E;  3T1Y E;  1UDN A;  1N32 I;  3QT8 A;  4GQU A;  4JI3 I;  4GKJ E;  2XEX A;  2GS8 A;  2BA1 G;  2Z5C A;  4DU8 A;  4JV5 I;  4DV7 I;  1OYP A;  4HAC B;  1K47 A;  1ZM4 A;  1Z0W A;  3U1Y A;  1XHK A;  4MQY A;  4JI8 I;  1HR0 E;  3LNU A;  4DPX A;  1N33 I;  1OYS A;  3T1H I;  4DR7 I;  1FNM A;  2GO4 A;  3LTO A;  2IOQ A;  1XNQ E;  4BA2 A;  1I94 E;  1N36 E;  4DV0 I;  4HY1 A;  3L7Z A;  2HFU A;  2HHH I;  1USU A;  3D4J A;  4WUB A;  1R6L A;  4FW4 A;  4B3M E;  2PNZ A;  4MYT A;  4OO1 A;  4DV3 I;  2JEB A;  4FW5 A;  4Z7C A;  3M7N G;  3WU6 A;  1ZM3 A;  2WNR A;  2Z5B B;  5DRQ A;  1PIE A;  4U3B A;  3WU4 A;  4DR5 E;  2J65 A;  4DR1 I;  2V2V A;  2R3V A;  4LF6 E;  1N34 I;  4OX9 E;  2JE6 A;  4LFB I;  4DR2 E;  4EMD A;  5K36 E;  4YY3 I;  2Z5C B;  4X65 E;  4LF8 I;  4NBQ A;  4DV5 E;  3ZKB A;  2HK3 A;  3CDJ A;  4IZK A;  2PNM A;  4IFD E;  4M1K A;  5A2Q C;  2A2D A;  4B3R E;  5GME A;  2PO2 B;  3UHM A;  3JAM Q;  2UXC E;  5IT9 Q;  1FWL A;  1OJ4 A;  4JI2 I;  3P3C A;  1IBL I;  3QT5 A;  2WW4 A;  4AQY I;  1P42 A;  4DUZ E;  3L7Z B;  1HNW E;  2HK2 A;  1Y5Y A;  3PS1 A;  4DUY E;  1PVG A;  1HNX E;  2PNZ B;  1H7U A;  4OO1 B;  4MU3 A;  1WUU A;  2JEB B;  1ZXN A;  4X64 E;  2WNR B;  4DR3 I;  4B3T E;  4JI0 I;  4USM A;  2NN6 F;  4LF7 E;  1ZM2 A;  4IS9 A;  1HNZ I;  1VIS A;  1RR9 A;  4DR4 I;  4OO1 D;  2V8P A;  2F1D A;  1UEK A;  4DXL A;  4DR6 I;  2C37 A;  2IOP A;  1XMQ E;  5K36 A;  2DEI A;  4MU4 A;  4JI5 I;  4GKK E;  2UXD E;  1FJG I;  3ZZ0 A;  2BV3 A;  5LMU I;  4IZK B;  3PRY A;  2UXB E;  4FWD A;  4DV6 I;  2R42 A;  2O1T A;  4IFD A;  1Y4S A;  3J80 C;  1Z5B A;  4FW9 A;  1Z0G A;  1J5E I;  4ZVI A;  4JI4 E;  4LF5 I;  2VQE I;  2O3Z A;  4DV4 E;  3M85 G;  3M6A A;  5ELW A;  1QZR A;  2Z5B A;  2E5L I;  3LPS A;  5JEA F;  2OI2 A;  2NPF A;  4LFA I;  2VQF I;  3KRN A;  4X62 I;  2C37 B;  5C0X F;  5K36 B;  5BR8 I;  2BA1 D;  2VF3 A;  3QT6 A;  2ZM6 E;  2F4V I;  3ZM7 A;  4X66 E;  4DV1 I;  4WUD A;  4K0K E;  4JI1 I;  5LMN I;  2NN6 B;  3V5R A;  4LCF A;  2DEJ A;  2AE8 A;  2PO2 A;  4IFD B;  4KHP E;  3K85 A;  1XNR I;  2IES A;  3P06 A;  4JI7 E;  4U3D A;  4DV2 E;  5K36 D;  3WU3 A;  1IBM E;  5JEA C;  3PYF A;  4DPW A;  2UUA E;  2ZBK B;  4DPY A;  3F0N A;  4NXM I;  3H1C A;  1XXE A;  5C0X C;  2O1W A;  4IFD D;  1USV A;  1Z0C A;  4LF9 E;  2E1R A;  2LJP A;  4LF4 I;  1YH8 A;  1Y6Z A;  3HUL A;  1IBK E;  2V2Q A;  5IWA E;  1VI7 A;  3M7N D;  2J7K A;  2UUC I;  1Z59 A;  1H72 C;  4FW6 A;  4JI6 I;  4YHH I;  3T1Y I;  1UDQ A;  1B63 A;  3HKM A;  3QT7 A;  4GKJ I;  1XMO E;  2GO3 A;  3J80 Q;  2NN6 E;  4FWH A;  5JEA B;  2CVE A;  4DU7 A;  4LFC E;  1Z0T A;  1HR0 I;  3P76 A;  3OTO E;  3B8H A;  5DNX A;  1Y60 A;  4JYA E;  2X7I A;  3GON A;  4JI5 E;  1D6T A;  3B82 A;  4UTG A;  1XNQ I;  1I94 I;  1N36 I;  3CDI A;  3ZZT A;  2CG9 A;  4IZJ B;  4B3S E;  4B3M I;  1ZM9 A;  2CGE A;  3K17 A;  4NXN E;  3PS2 A;  2BM1 A;  2HFS A;  4DPU A;  2UUB E;  3NZK A;  4DR5 I;  5DRR A;  3GLL A;  3PYG A;  4LF6 I;  2UU9 E;  4MYU A;  4OX9 I;  4DR2 I;  3CWV A;  1H74 A;  4X65 I;  5JEA E;  1Z5A A;  1Z0B A;  4DV5 I;  1FKA E;  1N32 E;  4P7A A;  2NN6 A;  3PYE A;  4JI3 E;  5C0X E;  4X62 E;  3PYD A;  5FLX C;  4JV5 E;  4DV7 E;  2PO0 B;  4B3R I;  2UXC I;  2C39 A;  1KVK A;  1PKP A;  1Z0V A;  4JI8 E;  4UT4 A;  1E3H A;  4DUZ I;  3GCM A;  4MDT A;  1HNW I;  5LL6 R;  2HKE A;  1N33 E;  1ZXM A;  2IER A;  4LCG A;  3T1H E;  1HNX I;  4DUY I;  4DR7 E;  2ZIT A;  3Q1Q A;  4X64 I;  4DV0 E;  1ELO A;  4N3O A;  2V2Z A;  2HHH E;  4JG4 A;  1Z5C A;  4P52 A;  4B3T I;  4DV3 E;  4LF7 I;  2JEA A;  4ISA A;  2C38 A;  1R6M A;  5A2Q Q;  1NHI A;  1N0U A;  5EL9 A;  2BA0 G;  3B78 A;  1XMQ I;  1N0V C;  2V34 A;  3J81 C;  4DR1 E;  5JEA A;  4GKK I;  2UXD I;  3H4L A;  3Q6M A;  1N34 E;  4LFB E;  2HKJ A;  4AM3 A;  4YY3 E;  2UXB I;  4LOM A;  5C0X A;  4LF8 E;  4KQV A;  4LPF A;  1BKN A;  2C39 B;  4ED4 A; 
#chains in the Genus database with same CATH homology
 4OZE A;  3P3E A;  2GO3 A;  4FW4 A;  3PS3 A;  4FW3 A;  3PS2 A;  1XXE A;  5DRO A;  4ISA A;  4FW5 A;  2JT2 A;  3UHM A;  4IS9 A;  3U1Y A;  4MQY A;  3NZK A;  3P3C A;  5DRQ A;  1YH8 A;  5DRP A;  3P76 A;  4U3B A;  4J3D A;  2O3Z A;  4LCH A;  5DRR A;  2J65 A;  3P3G A;  1P42 A;  4OKG A;  4FW7 A;  4MDT A;  2VES A;  4LCF A;  2IER A;  4LCG A;  1YHC A;  2GO4 A;  4FW6 A;  2IES A;  3PS1 A;  4U3D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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