4OZEA

A.aolicus lpxc in complex with native product
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFCFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic insight from the crystal structure of A.aolicus LpxC in the presence of product
rcsb
molecule tags Hydrolase
source organism Aquifex aeolicus
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 95
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2014-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4ozeA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4ozeA02
3NZKA 5DRPA 4FW7A 5DRQA 3PS2A 3PS1A 4U3BA 4LCGA 3U1YA 4MDTA 4LCFA 5DRRA 1YHCA 2O3ZA 2IERA 3P3CA 4FW6A 2GO4A 4LCHA 4OZEA 2J65A 1P42A 4FW5A 2IESA 4OKGA 4J3DA 3P3GA 4U3DA 2GO3A 3PS3A 2JT2A 3P76A 1YH8A 2VESA 4FW3A 4MQYA 1XXEA 4FW4A 4IS9A 3UHMA 4ISAA 5DROA 3P3EA
chains in the Genus database with same CATH superfamily
2F1DA 1E3HA 3M85D 4JI4I 1S4EA 4UT4A 4MU0A 4IFDE 2JEBA 4LFCE 1R6MA 4MDTA 2HHHI 2NN6F 4X66I 2HKEA 2HFSA 4DR4I 1PVGA 4NXMI 2O1TA 4JI4E 2V2VA 5EKWA 3QT8A 1PIEA 4BA1B 4AM3A 2HHHE 4DV0E 4X66E 4QNKA 1B62A 4DR3E 1H74A 3K85A 5A2QC 4OO1C 4M1KA 4FW4A 3PYFA 1XMOI 3GONA 4B3RE 3LNUA 4AIMA 2DEIA 4BA1A 4USKA 4FWDA 3ZZ0A 4GKKI 1N32I 1XMOE 5L3JA 3M85G 1Z59A 2CG9A 1EI1A 5BR8I 4IZJD 4FW6A 1Y5YA 3J80C 1Y60A 3V2UC 4LFBI 2JT2A 5BR8E 4P52A 4IZJB 5DROA 2UUAI 1UDNA 4DR6E 4LFBE 4UTGA 2JEAB 4YY3I 3T1YI 1XNQI 4U3BA 4DR5I 4XTJA 4IZJA 4JYAI 2Q2EB 2UUAE 4DR1E 2HK3A 4YY3E 2F4VE 3K17A 3T1YE 1KKHA 2JEAA 4EMDA 2O1WA 2OI2A 1OYSA 3P3GA 4JYAE 2GO3A 4OO1E 3LTOA 4AQYE 1N36E 2IOQA 3PYGA 4URLA 2AE8A 4IS9A 5K36C 1Y6ZA 3OTOE 4DPTA 2GS8A 1DARA 4N3OA 4MU3A 5C0XC 1Z0EA 2HK2A 3V5RA 5EL9A 1N0UA 2VQEI 2BA1D 4DV2I 3U1YA 5GMDA 1FNMA 1Z0CA 1J5EI 4HACB 4LF4I 4JI2E 2V2QA 3QT7A 1P42A 2VQEE 4DV2E 5JEAF 4IFDD 3JAMQ 2PO0A 4NXNE 2NPFA 4DV1E 4LF4E 2A2CA 3U1KA 4GKJE 2UXDI 4HACA 4DUYE 4WUBA 1OYRA 2CGEA 4JI3E 4JI6I 3UHMA 4GQUA 3NZKA 4DPXA 2EFGA 2UUCE 4JI8I 2UXDE 1HNWI 4B3SI 5LMNI 4LCFA 1UEKA 4FW9A 2BA1G 2NN6C 4LOMA 4PRVA 4LCHA 4PRXA 1S16A 4DPUA 4IFDA 4DUZI 1I94I 4JI8E 4PU9A 1HNWE 4JG4A 1IBME 4B3SE 5IT9C 1XNRE 1ZXNA 1WUUA 1RR9A 5K36E 2O1UA 4MQYA 5GMEA 5C0XE 4DUZE 4LFCI 3P3EA 1N0VC 4Z7YA 4DV4I 2O1VA 1NHIA 4MYTA 4LCGA 1RHYA 2ZM6I 4DV0I 2O3ZA 3B4TA 4DV4E 1FKAE 4DR3I 3Q6NA 1H7UA 2J7KA 3GCMA 1MX0A 2X36A 5DNLA 4B3RI 1PKPA 2ZM6E 1FWKA 2R42A 4OX9I 2DEJA 4FW3A 2GQ0A 2ZBKB 3ZKDA 4YHHI 3GLLA 1A6FA 2C38B 4FW7A 5DRQA 4OX9E 4DR2I 2C37A 4YHHE 1D6TA 1RREA 2NN6E 3P06A 1YHCA 1UDOA 2IERA 3F0NA 3P3CA 2GO4A 4DR2E 2R3VA 5FLXC 1R6LA 2C38A 3J81Q 4K0KI 4JV5I 4DR6I 1KVKA 1YH8A 1Z0BA 5IWAE 2UXCE 1EA6A 4K0KE 4JV5E 5FWKA 4DR1I 2F4VI 3K1JA 1H72C 4HYMA 3WU3A 3CWVA 4DPWA 2VF3A 4DV3I 3H4LA 4KHPE 5A2QQ 3T1HI 4AQYI 1N36I 4FN5A 4ED4A 2V2ZA 3OTOI 4DV3E 1ZM4A 5JEAC 2PO2B 3T1HE 2XEXA 3CDIA 2VQFI 4DPYA 1USVA 1N34I 1HK7A 1N33I 2JE6B 1MU5A 3J80Q 4JI2I 4MU1A 1Z0VA 3PS1A 4DV5E 2A2DA 2PO0B 2VQFE 2PO2A 3J7AM 1N34E 4NXNI 1N33E 4DV1I 3HULA 2V34A 2E5LI 1Z5CA 2E1RA 4GKJI 2JE6A 3WU5A 4OKGA 3B8HA 1Y4SA 4DUYI 3DD6A 4JI3I 4LF6I 3HJCA 3P76A 2UUCI 1HNXE 1E3PA 2E5LE 3M7ND 3ZKBA 4IZKA 4LF6E 1FJGE 4IFDB 4FWHA 1Z0WA 4B3TE 1USUA 1UDQA 1IBMI 1XNRI 1ZM9A 4WUCA 3KRNA 1NHJA 3J7AG 1MG7A 5JEAE 1ZM3A 2V8PA 1BKNA 4LF9I 1ELOA 1HR0I 1Z5BA 1XXEA 2BM1A 1Y4UA 1ZXMA 3ZM7A 1IBKI 2AJ4A 4LF9E 4AIDA 3M7NG 2Z5BB 1HR0E 4IFDF 2Z5EA 2PNMA 3HKMA 1IBKE 3ZZTA 1H7SA 2HFUA 2Z5BA 2PO1A 2IOPA 2C37B 2UUBI 2UU9I 3J81C 4DU7A 4QNJA 1XMQE 1H73A 4HXZA 5DRPA 4DR7E 2UUBE 4OO1D 5IT9Q 4LFAE 4LPFA 2UU9E 3QT5A 3PYEA 4LF7I 4OO1B 5IWAI 4J3DA 2UXCI 4U3DA 4DR4E 4DXLA 4NXME 2BM0A 4LF7E 1QZRA 3PYDA 2WNRB 1NZ0A 4KHPI 4OO1A 3PS2A 3L7ZB 5DNXA 3Q6MA 4FWGA 4X62I 4JI5I 4NBQA 4JI7I 2WNRA 4GKKE 3WU4A 1N32E 2J65A 4ZVIA 4X62E 2IESA 3WU6A 4JI5E 4JI7E 3L7ZA 2HKJA 4OO1F 2BA0D 4DV5I 1KTVA 1B63A 5JEAD 4X64I 3JAMC 2WW4A 5FLXQ 1FWLA 1FI4A 4WUDA 5K36D 3H1CA 2PNZB 3B82A 5C0XD 4X64E 2C39B 5JEAB 5LL6R 1XNQE 1K47A 4LF5I 4IZKB 4DR5E 1HNXI 2PNLA 4FW5A 5K36B 3B78A 4LF8I 1FJGI 2PNZA 5C0XB 2WP8B 4X65I 4DU8A 1NHHA 2C39A 4LF5E 5JEAA 4B3TI 4DV7I 4ISAA 4MU4A 1Z0GA 2BA0G 2ZITA 4LF8E 4RPFA 5K36A 4Z7CA 4X65E 1ZM2A 4JI0I 2LJPA 3PRYA 5C0XA 2WP8A 4DV7E 4IFDC 2Z5CB 4JI1I 1UDSA 1OJ4A 4B3MI 1Z5AA 1U2RA 4OZEA 3QT6A 2X7IA 4JI0E 4DV6I 1VISA 3CDJA 1HNZI 1J5EE 2BV3A 2NN6D 4JI1E 3M6AA 5K36F 1IBLI 2Z5CA 4B3ME 5C0XF 4I3HA 4DV6E 2BR2B 1HNZE 4BA2B 3LPSA 4MYUA 2NN6B 4USMA 1IBLE 2UXBI 3ZZUA 4JI6E 2PO1B 1KIJA 5DRRA 3GMEA 5LMUI 3D4JA 1VI7A 2BR2A 4BA2A 3Q1QA 2UXBE 4R1FA 5LMNE 2NN6A 1XHKA 3PS3A 1XMQI 2CZ9A 4P7AA 5LMUE 2JEBB 4KQVA 2VESA 4HY1A 2CVEA 4DR7I 1OYPA 1I94E 1Z0TA 5ELWA 4LFAI
chains in the Genus database with same CATH topology
3NZKA 5DRPA 4FW7A 5DRQA 3PS2A 3PS1A 4U3BA 4LCGA 3U1YA 4MDTA 4LCFA 5DRRA 1YHCA 2O3ZA 2IERA 3P3CA 4FW6A 2GO4A 4LCHA 4OZEA 2J65A 1P42A 4FW5A 2IESA 4OKGA 4J3DA 3P3GA 4U3DA 2GO3A 3PS3A 2JT2A 3P76A 1YH8A 2VESA 4FW3A 4MQYA 1XXEA 4FW4A 4IS9A 3UHMA 4ISAA 5DROA 3P3EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NZK A;  5DRP A;  4FW7 A;  5DRQ A;  3PS2 A;  3PS1 A;  4U3B A;  4LCG A;  3U1Y A;  4MDT A;  4LCF A;  5DRR A;  1YHC A;  2O3Z A;  2IER A;  3P3C A;  4FW6 A;  2GO4 A;  4LCH A;  4OZE A;  2J65 A;  1P42 A;  4FW5 A;  2IES A;  4OKG A;  4J3D A;  3P3G A;  4U3D A;  2GO3 A;  3PS3 A;  2JT2 A;  3P76 A;  1YH8 A;  2VES A;  4FW3 A;  4MQY A;  1XXE A;  4FW4 A;  4IS9 A;  3UHM A;  4ISA A;  5DRO A;  3P3E A; 
#chains in the Genus database with same CATH topology
 2F1D A;  1E3H A;  3M85 D;  4JI4 I;  1S4E A;  4UT4 A;  4MU0 A;  4IFD E;  2JEB A;  4LFC E;  1R6M A;  4MDT A;  2HHH I;  2NN6 F;  4X66 I;  2HKE A;  2HFS A;  4DR4 I;  1PVG A;  4NXM I;  2O1T A;  4JI4 E;  2V2V A;  5EKW A;  3QT8 A;  1PIE A;  4BA1 B;  4AM3 A;  2HHH E;  4DV0 E;  4X66 E;  4QNK A;  1B62 A;  4DR3 E;  1H74 A;  3K85 A;  5A2Q C;  4OO1 C;  4M1K A;  4FW4 A;  3PYF A;  1XMO I;  3GON A;  4B3R E;  3LNU A;  4AIM A;  2DEI A;  4BA1 A;  4USK A;  4FWD A;  3ZZ0 A;  4GKK I;  1N32 I;  1XMO E;  5L3J A;  3M85 G;  1Z59 A;  2CG9 A;  1EI1 A;  5BR8 I;  4IZJ D;  4FW6 A;  1Y5Y A;  3J80 C;  1Y60 A;  3V2U C;  4LFB I;  2JT2 A;  5BR8 E;  4P52 A;  4IZJ B;  5DRO A;  2UUA I;  1UDN A;  4DR6 E;  4LFB E;  4UTG A;  2JEA B;  4YY3 I;  3T1Y I;  1XNQ I;  4U3B A;  4DR5 I;  4XTJ A;  4IZJ A;  4JYA I;  2Q2E B;  2UUA E;  4DR1 E;  2HK3 A;  4YY3 E;  2F4V E;  3K17 A;  3T1Y E;  1KKH A;  2JEA A;  4EMD A;  2O1W A;  2OI2 A;  1OYS A;  3P3G A;  4JYA E;  2GO3 A;  4OO1 E;  3LTO A;  4AQY E;  1N36 E;  2IOQ A;  3PYG A;  4URL A;  2AE8 A;  4IS9 A;  5K36 C;  1Y6Z A;  3OTO E;  4DPT A;  2GS8 A;  1DAR A;  4N3O A;  4MU3 A;  5C0X C;  1Z0E A;  2HK2 A;  3V5R A;  5EL9 A;  1N0U A;  2VQE I;  2BA1 D;  4DV2 I;  3U1Y A;  5GMD A;  1FNM A;  1Z0C A;  1J5E I;  4HAC B;  4LF4 I;  4JI2 E;  2V2Q A;  3QT7 A;  1P42 A;  2VQE E;  4DV2 E;  5JEA F;  4IFD D;  3JAM Q;  2PO0 A;  4NXN E;  2NPF A;  4DV1 E;  4LF4 E;  2A2C A;  3U1K A;  4GKJ E;  2UXD I;  4HAC A;  4DUY E;  4WUB A;  1OYR A;  2CGE A;  4JI3 E;  4JI6 I;  3UHM A;  4GQU A;  3NZK A;  4DPX A;  2EFG A;  2UUC E;  4JI8 I;  2UXD E;  1HNW I;  4B3S I;  5LMN I;  4LCF A;  1UEK A;  4FW9 A;  2BA1 G;  2NN6 C;  4LOM A;  4PRV A;  4LCH A;  4PRX A;  1S16 A;  4DPU A;  4IFD A;  4DUZ I;  1I94 I;  4JI8 E;  4PU9 A;  1HNW E;  4JG4 A;  1IBM E;  4B3S E;  5IT9 C;  1XNR E;  1ZXN A;  1WUU A;  1RR9 A;  5K36 E;  2O1U A;  4MQY A;  5GME A;  5C0X E;  4DUZ E;  4LFC I;  3P3E A;  1N0V C;  4Z7Y A;  4DV4 I;  2O1V A;  1NHI A;  4MYT A;  4LCG A;  1RHY A;  2ZM6 I;  4DV0 I;  2O3Z A;  3B4T A;  4DV4 E;  1FKA E;  4DR3 I;  3Q6N A;  1H7U A;  2J7K A;  3GCM A;  1MX0 A;  2X36 A;  5DNL A;  4B3R I;  1PKP A;  2ZM6 E;  1FWK A;  2R42 A;  4OX9 I;  2DEJ A;  4FW3 A;  2GQ0 A;  2ZBK B;  3ZKD A;  4YHH I;  3GLL A;  1A6F A;  2C38 B;  4FW7 A;  5DRQ A;  4OX9 E;  4DR2 I;  2C37 A;  4YHH E;  1D6T A;  1RRE A;  2NN6 E;  3P06 A;  1YHC A;  1UDO A;  2IER A;  3F0N A;  3P3C A;  2GO4 A;  4DR2 E;  2R3V A;  5FLX C;  1R6L A;  2C38 A;  3J81 Q;  4K0K I;  4JV5 I;  4DR6 I;  1KVK A;  1YH8 A;  1Z0B A;  5IWA E;  2UXC E;  1EA6 A;  4K0K E;  4JV5 E;  5FWK A;  4DR1 I;  2F4V I;  3K1J A;  1H72 C;  4HYM A;  3WU3 A;  3CWV A;  4DPW A;  2VF3 A;  4DV3 I;  3H4L A;  4KHP E;  5A2Q Q;  3T1H I;  4AQY I;  1N36 I;  4FN5 A;  4ED4 A;  2V2Z A;  3OTO I;  4DV3 E;  1ZM4 A;  5JEA C;  2PO2 B;  3T1H E;  2XEX A;  3CDI A;  2VQF I;  4DPY A;  1USV A;  1N34 I;  1HK7 A;  1N33 I;  2JE6 B;  1MU5 A;  3J80 Q;  4JI2 I;  4MU1 A;  1Z0V A;  3PS1 A;  4DV5 E;  2A2D A;  2PO0 B;  2VQF E;  2PO2 A;  3J7A M;  1N34 E;  4NXN I;  1N33 E;  4DV1 I;  3HUL A;  2V34 A;  2E5L I;  1Z5C A;  2E1R A;  4GKJ I;  2JE6 A;  3WU5 A;  4OKG A;  3B8H A;  1Y4S A;  4DUY I;  3DD6 A;  4JI3 I;  4LF6 I;  3HJC A;  3P76 A;  2UUC I;  1HNX E;  1E3P A;  2E5L E;  3M7N D;  3ZKB A;  4IZK A;  4LF6 E;  1FJG E;  4IFD B;  4FWH A;  1Z0W A;  4B3T E;  1USU A;  1UDQ A;  1IBM I;  1XNR I;  1ZM9 A;  4WUC A;  3KRN A;  1NHJ A;  3J7A G;  1MG7 A;  5JEA E;  1ZM3 A;  2V8P A;  1BKN A;  4LF9 I;  1ELO A;  1HR0 I;  1Z5B A;  1XXE A;  2BM1 A;  1Y4U A;  1ZXM A;  3ZM7 A;  1IBK I;  2AJ4 A;  4LF9 E;  4AID A;  3M7N G;  2Z5B B;  1HR0 E;  4IFD F;  2Z5E A;  2PNM A;  3HKM A;  1IBK E;  3ZZT A;  1H7S A;  2HFU A;  2Z5B A;  2PO1 A;  2IOP A;  2C37 B;  2UUB I;  2UU9 I;  3J81 C;  4DU7 A;  4QNJ A;  1XMQ E;  1H73 A;  4HXZ A;  5DRP A;  4DR7 E;  2UUB E;  4OO1 D;  5IT9 Q;  4LFA E;  4LPF A;  2UU9 E;  3QT5 A;  3PYE A;  4LF7 I;  4OO1 B;  5IWA I;  4J3D A;  2UXC I;  4U3D A;  4DR4 E;  4DXL A;  4NXM E;  2BM0 A;  4LF7 E;  1QZR A;  3PYD A;  2WNR B;  1NZ0 A;  4KHP I;  4OO1 A;  3PS2 A;  3L7Z B;  5DNX A;  3Q6M A;  4FWG A;  4X62 I;  4JI5 I;  4NBQ A;  4JI7 I;  2WNR A;  4GKK E;  3WU4 A;  1N32 E;  2J65 A;  4ZVI A;  4X62 E;  2IES A;  3WU6 A;  4JI5 E;  4JI7 E;  3L7Z A;  2HKJ A;  4OO1 F;  2BA0 D;  4DV5 I;  1KTV A;  1B63 A;  5JEA D;  4X64 I;  3JAM C;  2WW4 A;  5FLX Q;  1FWL A;  1FI4 A;  4WUD A;  5K36 D;  3H1C A;  2PNZ B;  3B82 A;  5C0X D;  4X64 E;  2C39 B;  5JEA B;  5LL6 R;  1XNQ E;  1K47 A;  4LF5 I;  4IZK B;  4DR5 E;  1HNX I;  2PNL A;  4FW5 A;  5K36 B;  3B78 A;  4LF8 I;  1FJG I;  2PNZ A;  5C0X B;  2WP8 B;  4X65 I;  4DU8 A;  1NHH A;  2C39 A;  4LF5 E;  5JEA A;  4B3T I;  4DV7 I;  4ISA A;  4MU4 A;  1Z0G A;  2BA0 G;  2ZIT A;  4LF8 E;  4RPF A;  5K36 A;  4Z7C A;  4X65 E;  1ZM2 A;  4JI0 I;  2LJP A;  3PRY A;  5C0X A;  2WP8 A;  4DV7 E;  4IFD C;  2Z5C B;  4JI1 I;  1UDS A;  1OJ4 A;  4B3M I;  1Z5A A;  1U2R A;  4OZE A;  3QT6 A;  2X7I A;  4JI0 E;  4DV6 I;  1VIS A;  3CDJ A;  1HNZ I;  1J5E E;  2BV3 A;  2NN6 D;  4JI1 E;  3M6A A;  5K36 F;  1IBL I;  2Z5C A;  4B3M E;  5C0X F;  4I3H A;  4DV6 E;  2BR2 B;  1HNZ E;  4BA2 B;  3LPS A;  4MYU A;  2NN6 B;  4USM A;  1IBL E;  2UXB I;  3ZZU A;  4JI6 E;  2PO1 B;  1KIJ A;  5DRR A;  3GME A;  5LMU I;  3D4J A;  1VI7 A;  2BR2 A;  4BA2 A;  3Q1Q A;  2UXB E;  4R1F A;  5LMN E;  2NN6 A;  1XHK A;  3PS3 A;  1XMQ I;  2CZ9 A;  4P7A A;  5LMU E;  2JEB B;  4KQV A;  2VES A;  4HY1 A;  2CVE A;  4DR7 I;  1OYP A;  1I94 E;  1Z0T A;  5ELW A;  4LFA I; 
#chains in the Genus database with same CATH homology
 3NZK A;  5DRP A;  4FW7 A;  5DRQ A;  3PS2 A;  3PS1 A;  4U3B A;  4LCG A;  3U1Y A;  4MDT A;  4LCF A;  5DRR A;  1YHC A;  2O3Z A;  2IER A;  3P3C A;  4FW6 A;  2GO4 A;  4LCH A;  4OZE A;  2J65 A;  1P42 A;  4FW5 A;  2IES A;  4OKG A;  4J3D A;  3P3G A;  4U3D A;  2GO3 A;  3PS3 A;  2JT2 A;  3P76 A;  1YH8 A;  2VES A;  4FW3 A;  4MQY A;  1XXE A;  4FW4 A;  4IS9 A;  3UHM A;  4ISA A;  5DRO A;  3P3E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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