5DNXA

Crystal structure of igpd from pyrococcus furiosus in complex with (r)-c348
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
176
structure length
176
Chain Sequence
MRRTTKETDIIVEIGKKGEIKTNDLILDHMLTAFAFYLGKDMRITATYDLRHHLWEDIGITLGEALRENLPEKFTRFGNAIMPMDDALVLVSVDISNRPYANVDVNIKDAEEGFAVSLLKEFVWGLARGLRATIHIKQLSGENAHHIVEAAFKGLGMALRVATKESERVESTKGVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.
pubmed doi rcsb
molecule tags Lyase
source organism Pyrococcus furiosus
molecule keywords Imidazoleglycerol-phosphate dehydratase
total genus 60
structure length 176
sequence length 176
chains with identical sequence B, C
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2015-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 5dnxA02
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 5dnxA01
1RHYA 4GQUA 5DNLA 5EL9A 2AE8A 4QNKA 4MU4A 4QNJA 4MU3A 5ELWA 4MU1A 5EKWA 5DNXA 4LOMA 2F1DA 4LPFA 4MU0A
chains in the Genus database with same CATH superfamily
1RHYA 2VQEE 2JEBA 2PO0A 2C38B 4LF9E 5C0XE 1VISA 4RPFA 4DV2E 4IZJB 4MU4A 3ZZUA 4JYAE 3HJCA 5DNXA 4LOMA 4IFDD 4IFDF 5JEAC 2V2ZA 1Y4SA 2HHHI 4DUZE 1IBKE 1Y6ZA 3JAMQ 1XMQI 4FW6A 4QNKA 3Q6NA 4JI7I 3GCMA 4NXNE 4R1FA 4BA2B 4LCFA 1Z5CA 4MYUA 4DR3E 3J7AG 4YHHI 4DR4I 1FNMA 2JE6A 1N33I 1KKHA 1K47A 4FW4A 4FWGA 4OZEA 3GLLA 3P3GA 1J5EI 3P76A 2JEAB 5C0XD 5C0XF 4B3SI 2Z5BA 4LFBI 2F4VI 2V34A 2J65A 2HHHE 1XMQE 2DEJA 4QNJA 4JI7E 2HK3A 1YHCA 4FWDA 4IZJD 3D4JA 4YHHE 4DR4E 3QT7A 5DNLA 1Y5YA 4YY3E 3PYEA 2C39B 4IZKA 1FI4A 1UDNA 4PRVA 2HFSA 4MQYA 3J80Q 4LFBE 2F4VE 4MU3A 4LCHA 1YH8A 3PYFA 4P7AA 1FJGI 1XMOI 2ZM6E 1IBMI 4DR2E 4GKKI 1XNQE 1FKAE 1ZM9A 1IBLI 1H7SA 2E5LI 2BA1G 4MU0A 1I94I 1HNWI 2JEBB 2PO0B 2BM0A 3GONA 3NZKA 2XEXA 2IESA 4FW9A 4LF6I 2Z5EA 4LCGA 2O1TA 3OTOI 1HNZE 4JI8I 1XMOE 4IFDC 1IBME 1Z0GA 1E3HA 5IT9Q 4PU9A 1Z5AA 1HNXI 1IBLE 4WUDA 2E5LE 2JE6B 1HNWE 1N0UA 3WU5A 5LMNI 1KIJA 4GQUA 4OO1C 3B8HA 2EFGA 1XNRE 2PO2A 4LF6E 2Z5BB 3PYGA 1Z0EA 3OTOE 1BKNA 1S4EA 4JI8E 1ZXNA 2NPFA 3HKMA 1HNXE 4JYAI 4ED4A 4LF4I 4ISAA 1IBKI 1HK7A 1Z0BA 2ZITA 5LMNE 4DV6E 5ELWA 4X64I 4IZKB 3J81Q 4UTGA 5K36C 4LF8E 5FLXQ 3K85A 2DEIA 2NN6D 2NN6F 2V8PA 2CGEA 1A6FA 3PS1A 4Z7YA 3K1JA 5DROA 4JI2I 4GKJI 3WU4A 2F1DA 4LF4E 4HY1A 1NHHA 2WP8A 2Q2EB 4DUYI 1Z0WA 1R6LA 4OX9I 4X64E 1KVKA 4OO1E 4HACA 4DR5I 4YY3I 4P52A 2UXDI 4UT4A 4JI2E 5L3JA 3ZKBA 4GKJE 3CWVA 2ZBKB 3T1YI 2UU9I 1MG7A 4DPUA 4BA1B 3U1KA 4KQVA 4LFAE 2VQFE 2O1UA 3CDJA 4DUYE 2GS8A 4OX9E 1RR9A 4M1KA 3PRYA 1EI1A 4DPWA 1Z0VA 4LFCI 3U1YA 4N3OA 2ZM6I 4DR5E 2UUAI 1S16A 4DR2I 2UXDE 1XNQI 4U3BA 2UU9E 3P06A 1Z59A 4WUBA 1USUA 3M85D 3T1YE 4KHPE 3V5RA 3ZKDA 4U3DA 2GO4A 3ZZ0A 2PO2B 4LPFA 2HKEA 4AQYE 5JEAE 3M7ND 3J80C 4IS9A 3L7ZA 2O1WA 2WNRA 3M85G 1EA6A 3B78A 4OO1A 1NZ0A 3T1HI 3H4LA 1HNZI 1Z5BA 4DV1E 4LFCE 3PS3A 3Q1QA 3ZM7A 2IOQA 4DV0I 2UUAE 4B3RE 2V2VA 3QT8A 3M6AA 1ELOA 4DXLA 1Y4UA 3LPSA 4MYTA 4URLA 4NXMI 2CZ9A 4B3TE 3B82A 2A2CA 1XNRI 2NN6C 4JI6I 1FWKA 3LTOA 3QT5A 4BA1A 4J3DA 3T1HE 5K36A 2WP8B 1HR0I 1QZRA 4WUCA 2BM1A 4DV0E 2IERA 2R3VA 2UUCI 5IT9C 1XHKA 4AM3A 2J7KA 3GMEA 2V2QA 4FW5A 4JI1I 4HACB 5JEAA 2HFUA 2JT2A 4DV6I 4DPTA 4NXME 3J7AM 4DV5E 2O1VA 4LF8I 5A2QQ 4K0KI 4JI6E 3LNUA 1U2RA 2AJ4A 1ZM2A 2BV3A 5C0XC 1HR0E 3P3CA 1FWLA 2UUCE 4JI0I 4FWHA 5EL9A 4JI1E 2UXCI 4DV3I 1N0VC 4LF5I 3K17A 4AIDA 1PVGA 4IFDB 1MU5A 4K0KE 2LJPA 1OJ4A 3P3EA 5FLXC 3CDIA 2AE8A 4OKGA 3L7ZB 2WNRB 4IFDE 1E3PA 2Z5CA 4Z7CA 4LFAI 1N34E 4OO1B 1H73A 2VQFI 2C37A 4JI0E 5FWKA 2UXCE 4DV3E 3JAMC 5GMEA 4DR7E 2X7IA 1OYPA 4LF5E 1PIEA 3F0NA 4MDTA 2PO1A 5IWAE 3DD6A 1XXEA 4PRXA 2BR2A 1B63A 2WW4A 4KHPI 3PYDA 5LMUI 2HKJA 1ZM4A 4JI4I 4X66I 4AQYI 3Q6MA 1ZXMA 5K36B 4AIMA 3H1CA 4B3MI 4DU7A 4DV4E 1UDQA 2CVEA 1N32I 2PNZA 5DRRA 2NN6A 2BA0D 4DV1I 4OO1D 4OO1F 5K36E 4DR1I 3WU3A 2PNMA 5JEAB 4B3RI 1Y60A 3ZZTA 4IFDA 5BR8I 4DU8A 5LMUE 3V2UC 3WU6A 2BA0G 4JI4E 4USMA 4ZVIA 4X66E 2UXBI 3PS2A 1Z0TA 1RREA 4FW3A 1USVA 2X36A 4B3TI 4B3ME 4DR6I 1WUUA 1N32E 1N36I 3M7NG 4DR1E 5K36D 5K36F 1N33E 5C0XA 1D6TA 1OYSA 1Z0CA 1UDOA 2HK2A 1J5EE 5BR8E 4DPXA 4B3SE 1KTVA 1NHIA 2C38A 2UXBE 2PNLA 4JI5I 2A2DA 1DARA 5JEAD 5JEAF 4DV5I 4IZJA 4JG4A 4I3HA 4DR6E 2OI2A 2UUBI 2BA1D 2Z5CB 4JI3I 1N36E 2C37B 1NHJA 2GO3A 2E1RA 4DV7I 3HULA 4BA2A 4NBQA 4XTJA 2PO1B 2GQ0A 4USKA 4JI5E 2IOPA 5DRQA 2VF3A 2JEAA 4FN5A 2BR2B 4EMDA 2O3ZA 4HXZA 1UDSA 1ZM3A 2UUBE 4X65I 1FJGE 4JI3E 5A2QC 4JV5I 1PKPA 1MX0A 4GKKE 4DV7E 5GMDA 1N34I 1H74A 1I94E 2PNZB 2NN6B 3KRNA 5LL6R 4DPYA 4X62I 4LF7I 1VI7A 2C39A 1P42A 4DR7I 2VESA 2CG9A 2VQEI 5IWAI 2NN6E 1UEKA 4X65E 3J81C 4LF9I 1H72C 4JV5E 3UHMA 4DV2I 3QT6A 3B4TA 1H7UA 4DUZI 4MU1A 5EKWA 1B62A 5DRPA 1OYRA 1R6MA 4LF7E 4X62E 4NXNI 4DV4I 5C0XB 2R42A 4DR3I 4HYMA 4FW7A
chains in the Genus database with same CATH topology
1RHYA 4GQUA 5DNLA 5EL9A 2AE8A 4QNKA 4MU4A 4QNJA 4MU3A 5ELWA 4MU1A 5EKWA 5DNXA 4LOMA 2F1DA 4LPFA 4MU0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RHY A;  4GQU A;  5DNL A;  5EL9 A;  2AE8 A;  4QNK A;  4MU4 A;  4QNJ A;  4MU3 A;  5ELW A;  4MU1 A;  5EKW A;  5DNX A;  4LOM A;  2F1D A;  4LPF A;  4MU0 A; 
#chains in the Genus database with same CATH topology
 1RHY A;  2VQE E;  2JEB A;  2PO0 A;  2C38 B;  4LF9 E;  5C0X E;  1VIS A;  4RPF A;  4DV2 E;  4IZJ B;  4MU4 A;  3ZZU A;  4JYA E;  3HJC A;  5DNX A;  4LOM A;  4IFD D;  4IFD F;  5JEA C;  2V2Z A;  1Y4S A;  2HHH I;  4DUZ E;  1IBK E;  1Y6Z A;  3JAM Q;  1XMQ I;  4FW6 A;  4QNK A;  3Q6N A;  4JI7 I;  3GCM A;  4NXN E;  4R1F A;  4BA2 B;  4LCF A;  1Z5C A;  4MYU A;  4DR3 E;  3J7A G;  4YHH I;  4DR4 I;  1FNM A;  2JE6 A;  1N33 I;  1KKH A;  1K47 A;  4FW4 A;  4FWG A;  4OZE A;  3GLL A;  3P3G A;  1J5E I;  3P76 A;  2JEA B;  5C0X D;  5C0X F;  4B3S I;  2Z5B A;  4LFB I;  2F4V I;  2V34 A;  2J65 A;  2HHH E;  1XMQ E;  2DEJ A;  4QNJ A;  4JI7 E;  2HK3 A;  1YHC A;  4FWD A;  4IZJ D;  3D4J A;  4YHH E;  4DR4 E;  3QT7 A;  5DNL A;  1Y5Y A;  4YY3 E;  3PYE A;  2C39 B;  4IZK A;  1FI4 A;  1UDN A;  4PRV A;  2HFS A;  4MQY A;  3J80 Q;  4LFB E;  2F4V E;  4MU3 A;  4LCH A;  1YH8 A;  3PYF A;  4P7A A;  1FJG I;  1XMO I;  2ZM6 E;  1IBM I;  4DR2 E;  4GKK I;  1XNQ E;  1FKA E;  1ZM9 A;  1IBL I;  1H7S A;  2E5L I;  2BA1 G;  4MU0 A;  1I94 I;  1HNW I;  2JEB B;  2PO0 B;  2BM0 A;  3GON A;  3NZK A;  2XEX A;  2IES A;  4FW9 A;  4LF6 I;  2Z5E A;  4LCG A;  2O1T A;  3OTO I;  1HNZ E;  4JI8 I;  1XMO E;  4IFD C;  1IBM E;  1Z0G A;  1E3H A;  5IT9 Q;  4PU9 A;  1Z5A A;  1HNX I;  1IBL E;  4WUD A;  2E5L E;  2JE6 B;  1HNW E;  1N0U A;  3WU5 A;  5LMN I;  1KIJ A;  4GQU A;  4OO1 C;  3B8H A;  2EFG A;  1XNR E;  2PO2 A;  4LF6 E;  2Z5B B;  3PYG A;  1Z0E A;  3OTO E;  1BKN A;  1S4E A;  4JI8 E;  1ZXN A;  2NPF A;  3HKM A;  1HNX E;  4JYA I;  4ED4 A;  4LF4 I;  4ISA A;  1IBK I;  1HK7 A;  1Z0B A;  2ZIT A;  5LMN E;  4DV6 E;  5ELW A;  4X64 I;  4IZK B;  3J81 Q;  4UTG A;  5K36 C;  4LF8 E;  5FLX Q;  3K85 A;  2DEI A;  2NN6 D;  2NN6 F;  2V8P A;  2CGE A;  1A6F A;  3PS1 A;  4Z7Y A;  3K1J A;  5DRO A;  4JI2 I;  4GKJ I;  3WU4 A;  2F1D A;  4LF4 E;  4HY1 A;  1NHH A;  2WP8 A;  2Q2E B;  4DUY I;  1Z0W A;  1R6L A;  4OX9 I;  4X64 E;  1KVK A;  4OO1 E;  4HAC A;  4DR5 I;  4YY3 I;  4P52 A;  2UXD I;  4UT4 A;  4JI2 E;  5L3J A;  3ZKB A;  4GKJ E;  3CWV A;  2ZBK B;  3T1Y I;  2UU9 I;  1MG7 A;  4DPU A;  4BA1 B;  3U1K A;  4KQV A;  4LFA E;  2VQF E;  2O1U A;  3CDJ A;  4DUY E;  2GS8 A;  4OX9 E;  1RR9 A;  4M1K A;  3PRY A;  1EI1 A;  4DPW A;  1Z0V A;  4LFC I;  3U1Y A;  4N3O A;  2ZM6 I;  4DR5 E;  2UUA I;  1S16 A;  4DR2 I;  2UXD E;  1XNQ I;  4U3B A;  2UU9 E;  3P06 A;  1Z59 A;  4WUB A;  1USU A;  3M85 D;  3T1Y E;  4KHP E;  3V5R A;  3ZKD A;  4U3D A;  2GO4 A;  3ZZ0 A;  2PO2 B;  4LPF A;  2HKE A;  4AQY E;  5JEA E;  3M7N D;  3J80 C;  4IS9 A;  3L7Z A;  2O1W A;  2WNR A;  3M85 G;  1EA6 A;  3B78 A;  4OO1 A;  1NZ0 A;  3T1H I;  3H4L A;  1HNZ I;  1Z5B A;  4DV1 E;  4LFC E;  3PS3 A;  3Q1Q A;  3ZM7 A;  2IOQ A;  4DV0 I;  2UUA E;  4B3R E;  2V2V A;  3QT8 A;  3M6A A;  1ELO A;  4DXL A;  1Y4U A;  3LPS A;  4MYT A;  4URL A;  4NXM I;  2CZ9 A;  4B3T E;  3B82 A;  2A2C A;  1XNR I;  2NN6 C;  4JI6 I;  1FWK A;  3LTO A;  3QT5 A;  4BA1 A;  4J3D A;  3T1H E;  5K36 A;  2WP8 B;  1HR0 I;  1QZR A;  4WUC A;  2BM1 A;  4DV0 E;  2IER A;  2R3V A;  2UUC I;  5IT9 C;  1XHK A;  4AM3 A;  2J7K A;  3GME A;  2V2Q A;  4FW5 A;  4JI1 I;  4HAC B;  5JEA A;  2HFU A;  2JT2 A;  4DV6 I;  4DPT A;  4NXM E;  3J7A M;  4DV5 E;  2O1V A;  4LF8 I;  5A2Q Q;  4K0K I;  4JI6 E;  3LNU A;  1U2R A;  2AJ4 A;  1ZM2 A;  2BV3 A;  5C0X C;  1HR0 E;  3P3C A;  1FWL A;  2UUC E;  4JI0 I;  4FWH A;  5EL9 A;  4JI1 E;  2UXC I;  4DV3 I;  1N0V C;  4LF5 I;  3K17 A;  4AID A;  1PVG A;  4IFD B;  1MU5 A;  4K0K E;  2LJP A;  1OJ4 A;  3P3E A;  5FLX C;  3CDI A;  2AE8 A;  4OKG A;  3L7Z B;  2WNR B;  4IFD E;  1E3P A;  2Z5C A;  4Z7C A;  4LFA I;  1N34 E;  4OO1 B;  1H73 A;  2VQF I;  2C37 A;  4JI0 E;  5FWK A;  2UXC E;  4DV3 E;  3JAM C;  5GME A;  4DR7 E;  2X7I A;  1OYP A;  4LF5 E;  1PIE A;  3F0N A;  4MDT A;  2PO1 A;  5IWA E;  3DD6 A;  1XXE A;  4PRX A;  2BR2 A;  1B63 A;  2WW4 A;  4KHP I;  3PYD A;  5LMU I;  2HKJ A;  1ZM4 A;  4JI4 I;  4X66 I;  4AQY I;  3Q6M A;  1ZXM A;  5K36 B;  4AIM A;  3H1C A;  4B3M I;  4DU7 A;  4DV4 E;  1UDQ A;  2CVE A;  1N32 I;  2PNZ A;  5DRR A;  2NN6 A;  2BA0 D;  4DV1 I;  4OO1 D;  4OO1 F;  5K36 E;  4DR1 I;  3WU3 A;  2PNM A;  5JEA B;  4B3R I;  1Y60 A;  3ZZT A;  4IFD A;  5BR8 I;  4DU8 A;  5LMU E;  3V2U C;  3WU6 A;  2BA0 G;  4JI4 E;  4USM A;  4ZVI A;  4X66 E;  2UXB I;  3PS2 A;  1Z0T A;  1RRE A;  4FW3 A;  1USV A;  2X36 A;  4B3T I;  4B3M E;  4DR6 I;  1WUU A;  1N32 E;  1N36 I;  3M7N G;  4DR1 E;  5K36 D;  5K36 F;  1N33 E;  5C0X A;  1D6T A;  1OYS A;  1Z0C A;  1UDO A;  2HK2 A;  1J5E E;  5BR8 E;  4DPX A;  4B3S E;  1KTV A;  1NHI A;  2C38 A;  2UXB E;  2PNL A;  4JI5 I;  2A2D A;  1DAR A;  5JEA D;  5JEA F;  4DV5 I;  4IZJ A;  4JG4 A;  4I3H A;  4DR6 E;  2OI2 A;  2UUB I;  2BA1 D;  2Z5C B;  4JI3 I;  1N36 E;  2C37 B;  1NHJ A;  2GO3 A;  2E1R A;  4DV7 I;  3HUL A;  4BA2 A;  4NBQ A;  4XTJ A;  2PO1 B;  2GQ0 A;  4USK A;  4JI5 E;  2IOP A;  5DRQ A;  2VF3 A;  2JEA A;  4FN5 A;  2BR2 B;  4EMD A;  2O3Z A;  4HXZ A;  1UDS A;  1ZM3 A;  2UUB E;  4X65 I;  1FJG E;  4JI3 E;  5A2Q C;  4JV5 I;  1PKP A;  1MX0 A;  4GKK E;  4DV7 E;  5GMD A;  1N34 I;  1H74 A;  1I94 E;  2PNZ B;  2NN6 B;  3KRN A;  5LL6 R;  4DPY A;  4X62 I;  4LF7 I;  1VI7 A;  2C39 A;  1P42 A;  4DR7 I;  2VES A;  2CG9 A;  2VQE I;  5IWA I;  2NN6 E;  1UEK A;  4X65 E;  3J81 C;  4LF9 I;  1H72 C;  4JV5 E;  3UHM A;  4DV2 I;  3QT6 A;  3B4T A;  1H7U A;  4DUZ I;  4MU1 A;  5EKW A;  1B62 A;  5DRP A;  1OYR A;  1R6M A;  4LF7 E;  4X62 E;  4NXN I;  4DV4 I;  5C0X B;  2R42 A;  4DR3 I;  4HYM A;  4FW7 A; 
#chains in the Genus database with same CATH homology
 1RHY A;  4GQU A;  5DNL A;  5EL9 A;  2AE8 A;  4QNK A;  4MU4 A;  4QNJ A;  4MU3 A;  5ELW A;  4MU1 A;  5EKW A;  5DNX A;  4LOM A;  2F1D A;  4LPF A;  4MU0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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