5DRRA

Crystal structure of the pseudomonas aeruginosa lpxc/lpc-058 complex
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
296
structure length
296
Chain Sequence
MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
source organism Pseudomonas aeruginosa (strain atcc 15692 / pao1 / 1c / prs 101 / lmg 12228)
publication title Drug design from the cryptic inhibitor envelope.
pubmed doi rcsb
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 96
structure length 296
sequence length 296
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2015-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 5drrA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 5drrA02
2IESA 2JT2A 3P3GA 4IS9A 4OZEA 4MQYA 2J65A 2GO3A 4FW7A 4FW6A 5DRRA 4LCHA 3P3EA 4LCFA 3PS1A 4FW5A 4U3BA 4U3DA 2VESA 3U1YA 4ISAA 2GO4A 1XXEA 4FW4A 1P42A 5DRQA 5DRPA 4MDTA 1YH8A 1YHCA 4OKGA 5DROA 3P3CA 4J3DA 3PS3A 3UHMA 4LCGA 3PS2A 4FW3A 3NZKA 2IERA 3P76A 2O3ZA
chains in the Genus database with same CATH superfamily
4Z7YA 4X64E 1ZXMA 4MYTA 4ED4A 3ZZ0A 2VQEI 4JI6E 2BA1G 5JEAE 2HHHE 3B4TA 1XMQE 1OYPA 3T1HE 2Z5EA 2GS8A 4EMDA 1KIJA 2GO4A 1USVA 4JI5E 4IZJB 5DRQA 4IFDE 3WU4A 2NN6A 1A6FA 4XTJA 2PO2A 3L7ZA 3P06A 3PS2A 3J81Q 4NXNE 4OO1C 3LPSA 4MDTA 1N34E 4DR3E 1N0UA 2GQ0A 1H72C 1H74A 3OTOE 3U1KA 1EI1A 1XMOI 2A2CA 1HNZI 1R6MA 2BA1D 1Y4UA 4KHPE 2NN6B 4DV0E 1IBME 4B3SI 2PO2B 2HK2A 1MX0A 2E5LI 3PYDA 4DR7E 3GLLA 2UUCE 4JV5I 2OI2A 1NHIA 4OO1E 1XNRE 3CWVA 4HACB 2O3ZA 2V2ZA 4DV2E 1S16A 4AM3A 4AIDA 5C0XF 4K0KE 5K36E 4LF6I 3B78A 1PIEA 4JI0I 4B3TE 3J81C 1FJGE 1HNXE 4MU0A 1N33I 4IZKB 4WUCA 3PYGA 2WNRB 1B62A 3LTOA 2BR2A 4JI3E 1OJ4A 1WUUA 1ZM9A 1HR0I 1XNQI 4DR3I 2WP8B 1RHYA 2HFUA 2ZM6I 2R42A 2Z5BB 1IBKI 1I94I 3NZKA 1NHJA 3KRNA 1ELOA 2PO0B 2AE8A 1KVKA 3M85D 3ZZTA 2NPFA 4NBQA 4DPTA 3GONA 3P3EA 5GMDA 2BM0A 1BKNA 4I3HA 4QNKA 1Y4SA 2VQEE 4BA1A 4DUYI 4X62I 5C0XC 4YHHI 4ISAA 1DARA 1E3HA 2ZBKB 5IT9Q 5DROA 2PNZA 1D6TA 1OYSA 3PS3A 1Z0EA 5JEAD 4FWHA 1R6LA 3P76A 2Q2EB 1VI7A 2JEAB 4JG4A 2R3VA 4N3OA 4LF4I 1VISA 4IFDD 2O1WA 2UUBI 5C0XE 1Z5CA 2HK3A 1XMOE 2UXDI 3U1YA 1HNZE 4MU1A 1B63A 4KQVA 4B3SE 1FWLA 1NZ0A 1UEKA 3H4LA 2E5LE 2V34A 4IFDC 1HK7A 2NN6F 4AQYI 4JV5E 1K47A 4LF5I 2V2QA 4IZJA 5DNXA 1Z59A 4DV5I 4DV3I 5IT9C 3PYEA 1QZRA 4MU4A 4QNJA 4FW9A 5JEAB 4OO1D 4UTGA 1UDQA 4DV1I 5BR8I 2J7KA 4LF6E 4JI0E 1MG7A 3Q1QA 1N33E 1N0VC 4LCGA 1FWKA 4LOMA 5K36D 1ZM3A 1HR0E 1XNQE 2IESA 3P3GA 2ZM6E 3K1JA 1IBKE 2C38B 3D4JA 1I94E 4MYUA 3WU6A 1Z5AA 2NN6C 2UUAI 4FW5A 4HACA 5K36C 4U3DA 3HJCA 4DR6I 1NHHA 4DPWA 4BA2B 2IOPA 2HFSA 2CG9A 4FW4A 2C37B 1USUA 1ZXNA 1UDSA 3M6AA 4FN5A 4DUYE 1IBLI 4X62E 1KKHA 4YHHE 1FI4A 1J5EI 4X66I 2ZITA 4X65I 2JE6B 3PYFA 3QT8A 2O1TA 3LNUA 4IZKA 1Z0GA 4FWDA 1RREA 2UXBI 2WNRA 5A2QQ 3M85G 4JI7I 2NN6E 2J65A 3GCMA 4JI4I 2WP8A 2V2VA 4LCFA 2Z5BA 4NXMI 2LJPA 4LF4E 1XXEA 4DXLA 2PO0A 2UUBE 2UU9I 4LF9I 2UXDE 4JI2I 3ZM7A 1Z0BA 4J3DA 2O1VA 2JEBA 2CZ9A 4HYMA 4B3MI 4LFCI 3K85A 4DR2I 5C0XD 4IS9A 2UXCI 2CGEA 2HKJA 2DEIA 4FW6A 4AQYE 5DRRA 4OX9I 4LFAI 3ZKBA 4LF5E 4PRVA 1FNMA 2C39B 2JEBB 3QT6A 4DV5E 3V2UC 4DV3E 2WW4A 5A2QC 1P42A 2JEAA 4ZVIA 3QT5A 5BR8E 4DV1E 1HNWI 3ZZUA 4DR4I 3HULA 4FW3A 4JI8I 1N36I 1Z0VA 4GKJI 4P52A 3PRYA 2PO1B 1PKPA 4JI1I 1Y5YA 4DV4I 4JYAI 2VQFI 1Y6ZA 5C0XB 2UUAE 3HKMA 4LPFA 3Q6MA 4DR6E 4OKGA 3CDJA 5JEAA 5L3JA 4URLA 3JAMQ 4DR1I 1IBLE 3CDIA 1J5EE 4X66E 4UT4A 2CVEA 4X65E 2GO3A 4RPFA 4LCHA 4IFDA 2BA0D 2UXBE 4JI7E 4U3BA 3F0NA 2VESA 3T1YI 4JI4E 2A2DA 3M7ND 4PRXA 5LMUI 4DV7I 2C38A 4NXME 1Y60A 5DNLA 4DU8A 2F4VI 4B3RI 4LF8I 4FWGA 3P3CA 2NN6D 4PU9A 5EL9A 3UHMA 5FLXQ 4IFDB 5LMNI 2UU9E 4YY3I 4LF9E 2IERA 4DV6I 2PNLA 4JI2E 1RR9A 2JT2A 1MU5A 2Z5CA 4BA2A 1Z0WA 2C37A 4B3ME 1Z5BA 4LFCE 1EA6A 4GKKI 4HXZA 5IWAI 4DR2E 4HY1A 2UXCE 1KTVA 2JE6A 4OO1A 3JAMC 1OYRA 4OX9E 4LFAE 2Z5CB 2E1RA 3B82A 4LF7I 1U2RA 4MU3A 4DUZI 1YH8A 1YHCA 3V5RA 4DR5I 5K36A 4LFBI 3ZKDA 1E3PA 4OO1B 1HNWE 1S4EA 4DPYA 4MQYA 4DR4E 1XHKA 4JI8E 4WUBA 1N32I 1N36E 5FLXC 3L7ZB 5ELWA 4GKJE 4M1KA 4R1FA 5K36B 2BM1A 4JI1E 3WU3A 2X7IA 4DV4E 4JYAE 2VQFE 1PVGA 2AJ4A 5LL6R 1ZM2A 1UDNA 1Z0CA 4X64I 2XEXA 2C39A 4JI6I 4WUDA 2PNMA 2HHHI 4P7AA 2V8PA 1XMQI 3T1HI 4DPXA 2EFGA 4DR1E 1ZM4A 4JI5I 4GQUA 4AIMA 1H7UA 1H73A 4NXNI 1N34I 3B8HA 2PO1A 3T1YE 3OTOI 4DPUA 4USKA 5LMUE 4DV7E 5C0XA 5GMEA 5JEAF 2F4VE 4B3RE 1UDOA 4Z7CA 4DV0I 4DU7A 4LF8E 4KHPI 2BR2B 1IBMI 3WU5A 2BV3A 5LMNE 4YY3E 2X36A 4DV6E 2F1DA 3J80Q 2BA0G 4DR7I 1H7SA 2VF3A 3QT7A 4IFDF 3DD6A 2UUCI 4GKKE 5IWAE 3M7NG 1XNRI 4USMA 5DRPA 4DV2I 5FWKA 1FKAE 4LF7E 3Q6NA 4BA1B 4K0KI 2O1UA 4DUZE 2IOQA 2HKEA 2DEJA 4B3TI 4OZEA 4DR5E 1FJGI 1HNXI 4LFBE 4IZJD 4FW7A 2PNZB 3GMEA 3PS1A 4JI3I 5JEAC 5EKWA 3K17A 1N32E 3J7AM 4OO1F 3J7AG 3J80C 3H1CA 1Z0TA 5K36F
chains in the Genus database with same CATH topology
2IESA 2JT2A 3P3GA 4IS9A 4OZEA 4MQYA 2J65A 2GO3A 4FW7A 4FW6A 5DRRA 4LCHA 3P3EA 4LCFA 3PS1A 4FW5A 4U3BA 4U3DA 2VESA 3U1YA 4ISAA 2GO4A 1XXEA 4FW4A 1P42A 5DRQA 5DRPA 4MDTA 1YH8A 1YHCA 4OKGA 5DROA 3P3CA 4J3DA 3PS3A 3UHMA 4LCGA 3PS2A 4FW3A 3NZKA 2IERA 3P76A 2O3ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IES A;  2JT2 A;  3P3G A;  4IS9 A;  4OZE A;  4MQY A;  2J65 A;  2GO3 A;  4FW7 A;  4FW6 A;  5DRR A;  4LCH A;  3P3E A;  4LCF A;  3PS1 A;  4FW5 A;  4U3B A;  4U3D A;  2VES A;  3U1Y A;  4ISA A;  2GO4 A;  1XXE A;  4FW4 A;  1P42 A;  5DRQ A;  5DRP A;  4MDT A;  1YH8 A;  1YHC A;  4OKG A;  5DRO A;  3P3C A;  4J3D A;  3PS3 A;  3UHM A;  4LCG A;  3PS2 A;  4FW3 A;  3NZK A;  2IER A;  3P76 A;  2O3Z A; 
#chains in the Genus database with same CATH topology
 4Z7Y A;  4X64 E;  1ZXM A;  4MYT A;  4ED4 A;  3ZZ0 A;  2VQE I;  4JI6 E;  2BA1 G;  5JEA E;  2HHH E;  3B4T A;  1XMQ E;  1OYP A;  3T1H E;  2Z5E A;  2GS8 A;  4EMD A;  1KIJ A;  2GO4 A;  1USV A;  4JI5 E;  4IZJ B;  5DRQ A;  4IFD E;  3WU4 A;  2NN6 A;  1A6F A;  4XTJ A;  2PO2 A;  3L7Z A;  3P06 A;  3PS2 A;  3J81 Q;  4NXN E;  4OO1 C;  3LPS A;  4MDT A;  1N34 E;  4DR3 E;  1N0U A;  2GQ0 A;  1H72 C;  1H74 A;  3OTO E;  3U1K A;  1EI1 A;  1XMO I;  2A2C A;  1HNZ I;  1R6M A;  2BA1 D;  1Y4U A;  4KHP E;  2NN6 B;  4DV0 E;  1IBM E;  4B3S I;  2PO2 B;  2HK2 A;  1MX0 A;  2E5L I;  3PYD A;  4DR7 E;  3GLL A;  2UUC E;  4JV5 I;  2OI2 A;  1NHI A;  4OO1 E;  1XNR E;  3CWV A;  4HAC B;  2O3Z A;  2V2Z A;  4DV2 E;  1S16 A;  4AM3 A;  4AID A;  5C0X F;  4K0K E;  5K36 E;  4LF6 I;  3B78 A;  1PIE A;  4JI0 I;  4B3T E;  3J81 C;  1FJG E;  1HNX E;  4MU0 A;  1N33 I;  4IZK B;  4WUC A;  3PYG A;  2WNR B;  1B62 A;  3LTO A;  2BR2 A;  4JI3 E;  1OJ4 A;  1WUU A;  1ZM9 A;  1HR0 I;  1XNQ I;  4DR3 I;  2WP8 B;  1RHY A;  2HFU A;  2ZM6 I;  2R42 A;  2Z5B B;  1IBK I;  1I94 I;  3NZK A;  1NHJ A;  3KRN A;  1ELO A;  2PO0 B;  2AE8 A;  1KVK A;  3M85 D;  3ZZT A;  2NPF A;  4NBQ A;  4DPT A;  3GON A;  3P3E A;  5GMD A;  2BM0 A;  1BKN A;  4I3H A;  4QNK A;  1Y4S A;  2VQE E;  4BA1 A;  4DUY I;  4X62 I;  5C0X C;  4YHH I;  4ISA A;  1DAR A;  1E3H A;  2ZBK B;  5IT9 Q;  5DRO A;  2PNZ A;  1D6T A;  1OYS A;  3PS3 A;  1Z0E A;  5JEA D;  4FWH A;  1R6L A;  3P76 A;  2Q2E B;  1VI7 A;  2JEA B;  4JG4 A;  2R3V A;  4N3O A;  4LF4 I;  1VIS A;  4IFD D;  2O1W A;  2UUB I;  5C0X E;  1Z5C A;  2HK3 A;  1XMO E;  2UXD I;  3U1Y A;  1HNZ E;  4MU1 A;  1B63 A;  4KQV A;  4B3S E;  1FWL A;  1NZ0 A;  1UEK A;  3H4L A;  2E5L E;  2V34 A;  4IFD C;  1HK7 A;  2NN6 F;  4AQY I;  4JV5 E;  1K47 A;  4LF5 I;  2V2Q A;  4IZJ A;  5DNX A;  1Z59 A;  4DV5 I;  4DV3 I;  5IT9 C;  3PYE A;  1QZR A;  4MU4 A;  4QNJ A;  4FW9 A;  5JEA B;  4OO1 D;  4UTG A;  1UDQ A;  4DV1 I;  5BR8 I;  2J7K A;  4LF6 E;  4JI0 E;  1MG7 A;  3Q1Q A;  1N33 E;  1N0V C;  4LCG A;  1FWK A;  4LOM A;  5K36 D;  1ZM3 A;  1HR0 E;  1XNQ E;  2IES A;  3P3G A;  2ZM6 E;  3K1J A;  1IBK E;  2C38 B;  3D4J A;  1I94 E;  4MYU A;  3WU6 A;  1Z5A A;  2NN6 C;  2UUA I;  4FW5 A;  4HAC A;  5K36 C;  4U3D A;  3HJC A;  4DR6 I;  1NHH A;  4DPW A;  4BA2 B;  2IOP A;  2HFS A;  2CG9 A;  4FW4 A;  2C37 B;  1USU A;  1ZXN A;  1UDS A;  3M6A A;  4FN5 A;  4DUY E;  1IBL I;  4X62 E;  1KKH A;  4YHH E;  1FI4 A;  1J5E I;  4X66 I;  2ZIT A;  4X65 I;  2JE6 B;  3PYF A;  3QT8 A;  2O1T A;  3LNU A;  4IZK A;  1Z0G A;  4FWD A;  1RRE A;  2UXB I;  2WNR A;  5A2Q Q;  3M85 G;  4JI7 I;  2NN6 E;  2J65 A;  3GCM A;  4JI4 I;  2WP8 A;  2V2V A;  4LCF A;  2Z5B A;  4NXM I;  2LJP A;  4LF4 E;  1XXE A;  4DXL A;  2PO0 A;  2UUB E;  2UU9 I;  4LF9 I;  2UXD E;  4JI2 I;  3ZM7 A;  1Z0B A;  4J3D A;  2O1V A;  2JEB A;  2CZ9 A;  4HYM A;  4B3M I;  4LFC I;  3K85 A;  4DR2 I;  5C0X D;  4IS9 A;  2UXC I;  2CGE A;  2HKJ A;  2DEI A;  4FW6 A;  4AQY E;  5DRR A;  4OX9 I;  4LFA I;  3ZKB A;  4LF5 E;  4PRV A;  1FNM A;  2C39 B;  2JEB B;  3QT6 A;  4DV5 E;  3V2U C;  4DV3 E;  2WW4 A;  5A2Q C;  1P42 A;  2JEA A;  4ZVI A;  3QT5 A;  5BR8 E;  4DV1 E;  1HNW I;  3ZZU A;  4DR4 I;  3HUL A;  4FW3 A;  4JI8 I;  1N36 I;  1Z0V A;  4GKJ I;  4P52 A;  3PRY A;  2PO1 B;  1PKP A;  4JI1 I;  1Y5Y A;  4DV4 I;  4JYA I;  2VQF I;  1Y6Z A;  5C0X B;  2UUA E;  3HKM A;  4LPF A;  3Q6M A;  4DR6 E;  4OKG A;  3CDJ A;  5JEA A;  5L3J A;  4URL A;  3JAM Q;  4DR1 I;  1IBL E;  3CDI A;  1J5E E;  4X66 E;  4UT4 A;  2CVE A;  4X65 E;  2GO3 A;  4RPF A;  4LCH A;  4IFD A;  2BA0 D;  2UXB E;  4JI7 E;  4U3B A;  3F0N A;  2VES A;  3T1Y I;  4JI4 E;  2A2D A;  3M7N D;  4PRX A;  5LMU I;  4DV7 I;  2C38 A;  4NXM E;  1Y60 A;  5DNL A;  4DU8 A;  2F4V I;  4B3R I;  4LF8 I;  4FWG A;  3P3C A;  2NN6 D;  4PU9 A;  5EL9 A;  3UHM A;  5FLX Q;  4IFD B;  5LMN I;  2UU9 E;  4YY3 I;  4LF9 E;  2IER A;  4DV6 I;  2PNL A;  4JI2 E;  1RR9 A;  2JT2 A;  1MU5 A;  2Z5C A;  4BA2 A;  1Z0W A;  2C37 A;  4B3M E;  1Z5B A;  4LFC E;  1EA6 A;  4GKK I;  4HXZ A;  5IWA I;  4DR2 E;  4HY1 A;  2UXC E;  1KTV A;  2JE6 A;  4OO1 A;  3JAM C;  1OYR A;  4OX9 E;  4LFA E;  2Z5C B;  2E1R A;  3B82 A;  4LF7 I;  1U2R A;  4MU3 A;  4DUZ I;  1YH8 A;  1YHC A;  3V5R A;  4DR5 I;  5K36 A;  4LFB I;  3ZKD A;  1E3P A;  4OO1 B;  1HNW E;  1S4E A;  4DPY A;  4MQY A;  4DR4 E;  1XHK A;  4JI8 E;  4WUB A;  1N32 I;  1N36 E;  5FLX C;  3L7Z B;  5ELW A;  4GKJ E;  4M1K A;  4R1F A;  5K36 B;  2BM1 A;  4JI1 E;  3WU3 A;  2X7I A;  4DV4 E;  4JYA E;  2VQF E;  1PVG A;  2AJ4 A;  5LL6 R;  1ZM2 A;  1UDN A;  1Z0C A;  4X64 I;  2XEX A;  2C39 A;  4JI6 I;  4WUD A;  2PNM A;  2HHH I;  4P7A A;  2V8P A;  1XMQ I;  3T1H I;  4DPX A;  2EFG A;  4DR1 E;  1ZM4 A;  4JI5 I;  4GQU A;  4AIM A;  1H7U A;  1H73 A;  4NXN I;  1N34 I;  3B8H A;  2PO1 A;  3T1Y E;  3OTO I;  4DPU A;  4USK A;  5LMU E;  4DV7 E;  5C0X A;  5GME A;  5JEA F;  2F4V E;  4B3R E;  1UDO A;  4Z7C A;  4DV0 I;  4DU7 A;  4LF8 E;  4KHP I;  2BR2 B;  1IBM I;  3WU5 A;  2BV3 A;  5LMN E;  4YY3 E;  2X36 A;  4DV6 E;  2F1D A;  3J80 Q;  2BA0 G;  4DR7 I;  1H7S A;  2VF3 A;  3QT7 A;  4IFD F;  3DD6 A;  2UUC I;  4GKK E;  5IWA E;  3M7N G;  1XNR I;  4USM A;  5DRP A;  4DV2 I;  5FWK A;  1FKA E;  4LF7 E;  3Q6N A;  4BA1 B;  4K0K I;  2O1U A;  4DUZ E;  2IOQ A;  2HKE A;  2DEJ A;  4B3T I;  4OZE A;  4DR5 E;  1FJG I;  1HNX I;  4LFB E;  4IZJ D;  4FW7 A;  2PNZ B;  3GME A;  3PS1 A;  4JI3 I;  5JEA C;  5EKW A;  3K17 A;  1N32 E;  3J7A M;  4OO1 F;  3J7A G;  3J80 C;  3H1C A;  1Z0T A;  5K36 F; 
#chains in the Genus database with same CATH homology
 2IES A;  2JT2 A;  3P3G A;  4IS9 A;  4OZE A;  4MQY A;  2J65 A;  2GO3 A;  4FW7 A;  4FW6 A;  5DRR A;  4LCH A;  3P3E A;  4LCF A;  3PS1 A;  4FW5 A;  4U3B A;  4U3D A;  2VES A;  3U1Y A;  4ISA A;  2GO4 A;  1XXE A;  4FW4 A;  1P42 A;  5DRQ A;  5DRP A;  4MDT A;  1YH8 A;  1YHC A;  4OKG A;  5DRO A;  3P3C A;  4J3D A;  3PS3 A;  3UHM A;  4LCG A;  3PS2 A;  4FW3 A;  3NZK A;  2IER A;  3P76 A;  2O3Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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