5DNXA

Crystal structure of igpd from pyrococcus furiosus in complex with (r)-c348
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
176
structure length
176
Chain Sequence
MRRTTKETDIIVEIGKKGEIKTNDLILDHMLTAFAFYLGKDMRITATYDLRHHLWEDIGITLGEALRENLPEKFTRFGNAIMPMDDALVLVSVDISNRPYANVDVNIKDAEEGFAVSLLKEFVWGLARGLRATIHIKQLSGENAHHIVEAAFKGLGMALRVATKESERVESTKGVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.
pubmed doi rcsb
molecule tags Lyase
source organism Pyrococcus furiosus
molecule keywords Imidazoleglycerol-phosphate dehydratase
total genus 60
structure length 176
sequence length 176
chains with identical sequence B, C
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2015-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 5dnxA02
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 5dnxA01
5DNLA 5EKWA 4LOMA 4QNJA 1RHYA 2F1DA 4QNKA 4MU4A 5DNXA 4GQUA 4MU3A 5ELWA 4LPFA 4MU0A 4MU1A 2AE8A 5EL9A
chains in the Genus database with same CATH superfamily
2IESA 2ZM6I 2Z5EA 1I94I 1PKPA 1OYPA 4JI0I 2E1RA 4OO1B 1XNQI 1E3HA 2PNLA 4HY1A 2VQFI 4FW7A 4Z7YA 2R42A 1OYRA 4UTGA 2CGEA 3T1HI 2IERA 1FWLA 4OX9E 2XEXA 4B3RI 5K36B 2X36A 4DV5I 3J7AM 2GS8A 3T1YE 4DUYE 1Z59A 4XTJA 4AM3A 4GKKI 1Z5BA 4IZJB 1RREA 3B4TA 2F4VE 4DR3E 2LJPA 3PYDA 1XMQE 4QNJA 1D6TA 3PS1A 5DRRA 4YY3E 4JI4E 4DR7I 2HKJA 4GKJI 1USVA 2JE6A 4LPFA 5L3JA 4LF8E 2DEJA 4LF6I 1HNZI 4B3SE 3F0NA 4PRVA 4WUCA 4B3ME 4LFAE 4UT4A 2HK3A 4MU0A 1Z5CA 2GQ0A 2PO1A 4X66E 5C0XE 4X65E 4LFBI 2EFGA 4LCGA 1R6MA 4DV0I 1N33I 4LOMA 3M6AA 4X64I 4FW3A 4DV7I 2UU9E 4MYTA 1XNRE 2JEBB 2BM0A 5BR8I 4LF7E 2F1DA 3PYGA 3HULA 3OTOI 2C37A 3K17A 4RPFA 2AE8A 1B63A 4JYAE 4YHHI 2HHHI 4LF5I 2ZM6E 2WNRB 4FW4A 1H7UA 1I94E 1YHCA 3WU5A 4JI0E 1XNQE 4DPYA 3CWVA 2VQFE 2CG9A 5JEAE 5IWAE 4ISAA 4DUZI 4DR6E 1Z5AA 3T1HE 4B3RE 4DV5E 1H74A 4KQVA 1UEKA 1UDQA 4IZKB 1IBLE 5C0XD 4QNKA 2CZ9A 1ZM9A 1R6LA 3DD6A 4WUBA 2J65A 2O1VA 2PNZA 5LMUI 2C39B 4DR7E 4MYUA 4PU9A 1QZRA 4DXLA 4LF6E 1HNZE 1Z0WA 3L7ZB 5FWKA 3J7AG 2X7IA 4MQYA 4JV5I 2HK2A 1N32E 1NHJA 4IFDD 4MU3A 3ZZ0A 1EA6A 4LFBE 4IFDB 2HFSA 4DPXA 1N34I 1N33E 2GO3A 5EL9A 5JEAD 2VQEI 1XMOE 4FWDA 5BR8E 4LFCE 1N36I 2JE6B 3KRNA 3H1CA 1Y60A 2O1WA 4MU4A 5DNXA 5C0XA 4JI2I 1XXEA 4X62I 2AJ4A 4YHHE 2C39A 1IBMI 2PO1B 1H73A 4M1KA 4LF5E 3CDIA 4DR4E 1UDOA 3Q6NA 1FWKA 3L7ZA 3NZKA 3PS2A 4DUZE 1FI4A 3ZZTA 2Z5BA 4NXMI 4IFDA 4ZVIA 4K0KI 3LPSA 2C37B 4DU7A 4JI7E 4JG4A 3ZKBA 2O1UA 4JI8E 4MDTA 3PYEA 3QT8A 5C0XC 5GMDA 1N0UA 1MG7A 5JEAA 1FNMA 4DV6I 5LL6R 1H72C 2E5LE 1A6FA 4FN5A 1HNXE 2GO4A 5LMUE 2UXDE 4DPTA 4DV4I 4DR1E 2ZITA 1ELOA 1K47A 2UXBE 4JI6I 1B62A 3M7ND 1UDNA 5FLXC 4JV5E 1PIEA 2PO2A 4IFDC 4P52A 4PRXA 4DV2E 2UUBI 2V2QA 1ZXNA 3QT6A 2BR2A 3CDJA 4FWHA 2A2DA 2CVEA 4U3DA 1N34E 3LTOA 2IOQA 1FJGI 5JEAC 3M85D 2PNZB 1UDSA 2VQEE 1MX0A 1NHHA 1NHIA 4DV3I 1WUUA 1N36E 1N0VC 3PYFA 4DR5I 2NN6E 3Q1QA 4JI2E 4USKA 4X62E 5C0XF 2A2CA 3WU3A 1J5EI 4NXNI 2HFUA 1OJ4A 3GLLA 1DARA 2Q2EB 4GKKE 4DPUA 1Y4SA 2IOPA 1RR9A 4FW6A 3B82A 4K0KE 1U2RA 4AIMA 2PO0A 1HR0I 5C0XB 2VF3A 4IFDF 1ZM2A 2BM1A 5EKWA 3QT7A 4HXZA 3T1YI 4DUYI 4EMDA 4GKJE 4DV6E 2UUCI 4LCFA 2WP8A 5JEAF 4AQYI 1NZ0A 4OO1E 3ZKDA 4P7AA 3GONA 2Z5CA 3K1JA 2R3VA 2O1TA 4JI6E 4YY3I 2Z5BB 4FW5A 3JAMQ 5K36E 2NN6D 2DEIA 3P06A 3M7NG 4DPWA 1XHKA 3J80Q 4DV0E 2UUBE 2V34A 4B3SI 4X64E 4DV7E 5FLXQ 4LFAI 5JEAB 3P76A 2BA1G 5LMNI 4WUDA 2UXCI 4URLA 1FJGE 2JEAA 3M85G 4FWGA 3OTOE 4AIDA 4LF9I 1USUA 1Y6ZA 5IT9C 4KHPI 4DR5E 2UU9I 2HHHE 3WU4A 4BA1A 4DR2I 2PO2B 2V2VA 1VI7A 2OI2A 3P3GA 3H4LA 1J5EE 4FW9A 1FKAE 2BR2B 2C38A 4JYAI 2V8PA 4GQUA 4BA2A 2HKEA 5A2QC 2J7KA 4OO1D 2ZBKB 3UHMA 2NN6A 1KVKA 1MU5A 1Z0GA 2V2ZA 5IWAI 2NPFA 4DR6I 5K36D 1HNWI 5DRQA 1HR0E 1E3PA 1Z0EA 4HYMA 1EI1A 1KTVA 5ELWA 3JAMC 3GCMA 4IZJD 2UUCE 3J80C 4DU8A 2BA0G 1OYSA 4AQYE 4JI5I 1IBLI 3PRYA 4DV1I 4ED4A 2NN6C 3V5RA 1P42A 4MU1A 4U3BA 4LF4I 2BA1D 1Z0CA 4HACA 2PO0B 1RHYA 3K85A 3J81C 4JI1I 1PVGA 2UUAI 3V2UC 1IBKI 1ZM3A 2O3ZA 4OO1A 1N32I 5LMNE 4JI3I 3QT5A 2UXCE 2WP8B 1H7SA 4B3TI 4LF9E 5K36A 1BKNA 3Q6MA 2Z5CB 5DNLA 1IBME 4KHPE 1XMOI 1VISA 4DR2E 5IT9Q 4LFCI 2PNMA 3P3CA 4IZJA 3U1KA 4OKGA 4R1FA 2VESA 4IFDE 2WW4A 4NXME 4OO1C 4OZEA 1S4EA 2JEAB 4DR4I 4IS9A 3PS3A 3HJCA 4OX9I 1ZXMA 5A2QQ 2NN6F 2JT2A 5K36C 1KIJA 4USMA 1Z0TA 4N3OA 1HNWE 3ZM7A 4BA1B 3P3EA 2BV3A 2BA0D 1Z0BA 4DV4E 4Z7CA 2F4VI 5DRPA 4DR3I 5DROA 4JI7I 1XMQI 2C38B 4JI8I 1HK7A 4JI5E 4BA2B 4JI4I 2JEBA 4J3DA 4NBQA 2NN6B 1ZM4A 2E5LI 4DV1E 1HNXI 2UXDI 4LF8I 4DR1I 3D4JA 4B3MI 4LF4E 1Z0VA 3B8HA 5GMEA 2UXBI 4X66I 1Y5YA 4I3HA 4JI1E 4X65I 2WNRA 2UUAE 1IBKE 1YH8A 3LNUA 4DV3E 3ZZUA 4JI3E 3U1YA 1Y4UA 4DV2I 3J81Q 4OO1F 3WU6A 4B3TE 1XNRI 3B78A 1S16A 4LF7I 5K36F 3GMEA 1KKHA 4NXNE 4HACB 4LCHA 4IZKA 3HKMA
chains in the Genus database with same CATH topology
5DNLA 5EKWA 4LOMA 4QNJA 1RHYA 2F1DA 4QNKA 4MU4A 5DNXA 4GQUA 4MU3A 5ELWA 4LPFA 4MU0A 4MU1A 2AE8A 5EL9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DNL A;  5EKW A;  4LOM A;  4QNJ A;  1RHY A;  2F1D A;  4QNK A;  4MU4 A;  5DNX A;  4GQU A;  4MU3 A;  5ELW A;  4LPF A;  4MU0 A;  4MU1 A;  2AE8 A;  5EL9 A; 
#chains in the Genus database with same CATH topology
 2IES A;  2ZM6 I;  2Z5E A;  1I94 I;  1PKP A;  1OYP A;  4JI0 I;  2E1R A;  4OO1 B;  1XNQ I;  1E3H A;  2PNL A;  4HY1 A;  2VQF I;  4FW7 A;  4Z7Y A;  2R42 A;  1OYR A;  4UTG A;  2CGE A;  3T1H I;  2IER A;  1FWL A;  4OX9 E;  2XEX A;  4B3R I;  5K36 B;  2X36 A;  4DV5 I;  3J7A M;  2GS8 A;  3T1Y E;  4DUY E;  1Z59 A;  4XTJ A;  4AM3 A;  4GKK I;  1Z5B A;  4IZJ B;  1RRE A;  3B4T A;  2F4V E;  4DR3 E;  2LJP A;  3PYD A;  1XMQ E;  4QNJ A;  1D6T A;  3PS1 A;  5DRR A;  4YY3 E;  4JI4 E;  4DR7 I;  2HKJ A;  4GKJ I;  1USV A;  2JE6 A;  4LPF A;  5L3J A;  4LF8 E;  2DEJ A;  4LF6 I;  1HNZ I;  4B3S E;  3F0N A;  4PRV A;  4WUC A;  4B3M E;  4LFA E;  4UT4 A;  2HK3 A;  4MU0 A;  1Z5C A;  2GQ0 A;  2PO1 A;  4X66 E;  5C0X E;  4X65 E;  4LFB I;  2EFG A;  4LCG A;  1R6M A;  4DV0 I;  1N33 I;  4LOM A;  3M6A A;  4X64 I;  4FW3 A;  4DV7 I;  2UU9 E;  4MYT A;  1XNR E;  2JEB B;  2BM0 A;  5BR8 I;  4LF7 E;  2F1D A;  3PYG A;  3HUL A;  3OTO I;  2C37 A;  3K17 A;  4RPF A;  2AE8 A;  1B63 A;  4JYA E;  4YHH I;  2HHH I;  4LF5 I;  2ZM6 E;  2WNR B;  4FW4 A;  1H7U A;  1I94 E;  1YHC A;  3WU5 A;  4JI0 E;  1XNQ E;  4DPY A;  3CWV A;  2VQF E;  2CG9 A;  5JEA E;  5IWA E;  4ISA A;  4DUZ I;  4DR6 E;  1Z5A A;  3T1H E;  4B3R E;  4DV5 E;  1H74 A;  4KQV A;  1UEK A;  1UDQ A;  4IZK B;  1IBL E;  5C0X D;  4QNK A;  2CZ9 A;  1ZM9 A;  1R6L A;  3DD6 A;  4WUB A;  2J65 A;  2O1V A;  2PNZ A;  5LMU I;  2C39 B;  4DR7 E;  4MYU A;  4PU9 A;  1QZR A;  4DXL A;  4LF6 E;  1HNZ E;  1Z0W A;  3L7Z B;  5FWK A;  3J7A G;  2X7I A;  4MQY A;  4JV5 I;  2HK2 A;  1N32 E;  1NHJ A;  4IFD D;  4MU3 A;  3ZZ0 A;  1EA6 A;  4LFB E;  4IFD B;  2HFS A;  4DPX A;  1N34 I;  1N33 E;  2GO3 A;  5EL9 A;  5JEA D;  2VQE I;  1XMO E;  4FWD A;  5BR8 E;  4LFC E;  1N36 I;  2JE6 B;  3KRN A;  3H1C A;  1Y60 A;  2O1W A;  4MU4 A;  5DNX A;  5C0X A;  4JI2 I;  1XXE A;  4X62 I;  2AJ4 A;  4YHH E;  2C39 A;  1IBM I;  2PO1 B;  1H73 A;  4M1K A;  4LF5 E;  3CDI A;  4DR4 E;  1UDO A;  3Q6N A;  1FWK A;  3L7Z A;  3NZK A;  3PS2 A;  4DUZ E;  1FI4 A;  3ZZT A;  2Z5B A;  4NXM I;  4IFD A;  4ZVI A;  4K0K I;  3LPS A;  2C37 B;  4DU7 A;  4JI7 E;  4JG4 A;  3ZKB A;  2O1U A;  4JI8 E;  4MDT A;  3PYE A;  3QT8 A;  5C0X C;  5GMD A;  1N0U A;  1MG7 A;  5JEA A;  1FNM A;  4DV6 I;  5LL6 R;  1H72 C;  2E5L E;  1A6F A;  4FN5 A;  1HNX E;  2GO4 A;  5LMU E;  2UXD E;  4DPT A;  4DV4 I;  4DR1 E;  2ZIT A;  1ELO A;  1K47 A;  2UXB E;  4JI6 I;  1B62 A;  3M7N D;  1UDN A;  5FLX C;  4JV5 E;  1PIE A;  2PO2 A;  4IFD C;  4P52 A;  4PRX A;  4DV2 E;  2UUB I;  2V2Q A;  1ZXN A;  3QT6 A;  2BR2 A;  3CDJ A;  4FWH A;  2A2D A;  2CVE A;  4U3D A;  1N34 E;  3LTO A;  2IOQ A;  1FJG I;  5JEA C;  3M85 D;  2PNZ B;  1UDS A;  2VQE E;  1MX0 A;  1NHH A;  1NHI A;  4DV3 I;  1WUU A;  1N36 E;  1N0V C;  3PYF A;  4DR5 I;  2NN6 E;  3Q1Q A;  4JI2 E;  4USK A;  4X62 E;  5C0X F;  2A2C A;  3WU3 A;  1J5E I;  4NXN I;  2HFU A;  1OJ4 A;  3GLL A;  1DAR A;  2Q2E B;  4GKK E;  4DPU A;  1Y4S A;  2IOP A;  1RR9 A;  4FW6 A;  3B82 A;  4K0K E;  1U2R A;  4AIM A;  2PO0 A;  1HR0 I;  5C0X B;  2VF3 A;  4IFD F;  1ZM2 A;  2BM1 A;  5EKW A;  3QT7 A;  4HXZ A;  3T1Y I;  4DUY I;  4EMD A;  4GKJ E;  4DV6 E;  2UUC I;  4LCF A;  2WP8 A;  5JEA F;  4AQY I;  1NZ0 A;  4OO1 E;  3ZKD A;  4P7A A;  3GON A;  2Z5C A;  3K1J A;  2R3V A;  2O1T A;  4JI6 E;  4YY3 I;  2Z5B B;  4FW5 A;  3JAM Q;  5K36 E;  2NN6 D;  2DEI A;  3P06 A;  3M7N G;  4DPW A;  1XHK A;  3J80 Q;  4DV0 E;  2UUB E;  2V34 A;  4B3S I;  4X64 E;  4DV7 E;  5FLX Q;  4LFA I;  5JEA B;  3P76 A;  2BA1 G;  5LMN I;  4WUD A;  2UXC I;  4URL A;  1FJG E;  2JEA A;  3M85 G;  4FWG A;  3OTO E;  4AID A;  4LF9 I;  1USU A;  1Y6Z A;  5IT9 C;  4KHP I;  4DR5 E;  2UU9 I;  2HHH E;  3WU4 A;  4BA1 A;  4DR2 I;  2PO2 B;  2V2V A;  1VI7 A;  2OI2 A;  3P3G A;  3H4L A;  1J5E E;  4FW9 A;  1FKA E;  2BR2 B;  2C38 A;  4JYA I;  2V8P A;  4GQU A;  4BA2 A;  2HKE A;  5A2Q C;  2J7K A;  4OO1 D;  2ZBK B;  3UHM A;  2NN6 A;  1KVK A;  1MU5 A;  1Z0G A;  2V2Z A;  5IWA I;  2NPF A;  4DR6 I;  5K36 D;  1HNW I;  5DRQ A;  1HR0 E;  1E3P A;  1Z0E A;  4HYM A;  1EI1 A;  1KTV A;  5ELW A;  3JAM C;  3GCM A;  4IZJ D;  2UUC E;  3J80 C;  4DU8 A;  2BA0 G;  1OYS A;  4AQY E;  4JI5 I;  1IBL I;  3PRY A;  4DV1 I;  4ED4 A;  2NN6 C;  3V5R A;  1P42 A;  4MU1 A;  4U3B A;  4LF4 I;  2BA1 D;  1Z0C A;  4HAC A;  2PO0 B;  1RHY A;  3K85 A;  3J81 C;  4JI1 I;  1PVG A;  2UUA I;  3V2U C;  1IBK I;  1ZM3 A;  2O3Z A;  4OO1 A;  1N32 I;  5LMN E;  4JI3 I;  3QT5 A;  2UXC E;  2WP8 B;  1H7S A;  4B3T I;  4LF9 E;  5K36 A;  1BKN A;  3Q6M A;  2Z5C B;  5DNL A;  1IBM E;  4KHP E;  1XMO I;  1VIS A;  4DR2 E;  5IT9 Q;  4LFC I;  2PNM A;  3P3C A;  4IZJ A;  3U1K A;  4OKG A;  4R1F A;  2VES A;  4IFD E;  2WW4 A;  4NXM E;  4OO1 C;  4OZE A;  1S4E A;  2JEA B;  4DR4 I;  4IS9 A;  3PS3 A;  3HJC A;  4OX9 I;  1ZXM A;  5A2Q Q;  2NN6 F;  2JT2 A;  5K36 C;  1KIJ A;  4USM A;  1Z0T A;  4N3O A;  1HNW E;  3ZM7 A;  4BA1 B;  3P3E A;  2BV3 A;  2BA0 D;  1Z0B A;  4DV4 E;  4Z7C A;  2F4V I;  5DRP A;  4DR3 I;  5DRO A;  4JI7 I;  1XMQ I;  2C38 B;  4JI8 I;  1HK7 A;  4JI5 E;  4BA2 B;  4JI4 I;  2JEB A;  4J3D A;  4NBQ A;  2NN6 B;  1ZM4 A;  2E5L I;  4DV1 E;  1HNX I;  2UXD I;  4LF8 I;  4DR1 I;  3D4J A;  4B3M I;  4LF4 E;  1Z0V A;  3B8H A;  5GME A;  2UXB I;  4X66 I;  1Y5Y A;  4I3H A;  4JI1 E;  4X65 I;  2WNR A;  2UUA E;  1IBK E;  1YH8 A;  3LNU A;  4DV3 E;  3ZZU A;  4JI3 E;  3U1Y A;  1Y4U A;  4DV2 I;  3J81 Q;  4OO1 F;  3WU6 A;  4B3T E;  1XNR I;  3B78 A;  1S16 A;  4LF7 I;  5K36 F;  3GME A;  1KKH A;  4NXN E;  4HAC B;  4LCH A;  4IZK A;  3HKM A; 
#chains in the Genus database with same CATH homology
 5DNL A;  5EKW A;  4LOM A;  4QNJ A;  1RHY A;  2F1D A;  4QNK A;  4MU4 A;  5DNX A;  4GQU A;  4MU3 A;  5ELW A;  4LPF A;  4MU0 A;  4MU1 A;  2AE8 A;  5EL9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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