3FAPA

Atomic structures of the rapamycin analogs in complex with both human fkbp12 and frb domain of frap
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
107
structure length
107
Chain Sequence
GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords FK506-BINDING PROTEIN
total genus 24
structure length 107
sequence length 107
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 1999-05-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00254 FKBP_C FKBP-type peptidyl-prolyl cis-trans isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.50.40 Alpha Beta Roll Chitinase A; domain 3 Chitinase A; domain 3 3fapA00
3O5DA 1P5QA 1Q1CA 4GGQA 3KAGA 1U79A 3NTPA 1Y0OA 1FKKA 4DH0A 3TC5A 1FKGA 3UQAA 1QZ2A 1FKJA 2LKNA 3O5KA 1D7JA 3O5EA 4JFMA 4ODRA 4TYOA 3CGNA 1BKFA 1ROUA 2XP8A 3I6CA 3O5LA 5HKGA 3KAIA 3NRKA 1Q6UA 3OOBA 1NMVA 3PRBA 4DRMA 3O5JA 4JFKA 1KT1A 4TNSA 2PV1A 2XP5A 4U84A 4IPXA 1J4IA 4W9OA 1J6YA 2PPNA 1FKSA 2ZQTA 1W26A 2RUQA 4IQCA 1NSGA 1F40A 2M08A 1QPFA 1ZK6A 2ZR6A 3KADA 5GPGA 4ODNA 2ZR5A 4DRQA 5BXJA 2FAPA 4MGVA 4DRPA 2F2DA 1F8AB 4MSPA 2XP3A 1M5YA 1FJDA 3O5FA 1PINA 4J4NA 3B7XA 4TX0A 3IHZA 4U86A 1N1AA 4DROA 2M2AA 2LGOA 1HXVA 1YW5A 2MPHA 2RQSA 2UZ5A 1FKDA 2ITKA 2DG3A 1FKLA 3IK8A 3UI6A 3PA7A 2KGJA 4ITZA 2F4EA 2XPAA 3UI5A 2MLXA 1J4RA 4G50A 2ZR4A 1FKIA 4TW8A 2XP9A 1FKBA 4ODOA 4QIBA 2DG4A 2LPVA 3IKDA 4IQ2A 4ODPA 4DT4A 3WH0A 3VAWA 3O5RA 1NMWA 1R9HA 1D6OA 3KCEA 4LAYA 4ODMA 1Q6IA 1T11A 4W9QA 1FD9A 2DG9A 4JFIA 2AWGA 2D9FA 5HTGA 4DRHA 4JYSA 3RFWA 2KE0A 4NNRA 4N19A 4DRKA 3PRDA 2IF4A 1L1PA 5HUAA 2K8IA 4BF8A 2RUDA 3KAHA 4ODKA 5HWCA 4FN2A 4ODQA 3EY6A 2RURA 2FKEA 2MLYA 1J4HA 5HWBA 3TDBA 4DRIA 2L2SA 4G2PA 3ODKA 3H9RB 2KI3A 2PPPA 1B6CA 1ZCNA 4TW7A 1FKRA 1ROTA 3JXVA 5HT1A 1C9HA 2RSEA 2VCDA 3RGCA 1D7HA 3LUOA 3UQIA 1JNTA 4LAXA 1A7XA 1YATA 3KABA 3NI6A 4O2TA 1JVWA 3TCZA 2MNTA 2JZVA 3FAPA 4LAWA 4C02B 3O5QA 5D75A 4J4OA 4JFJA 1FKFA 1FKHA 2LJ4A 2KR7A 3IKGA 1TCOC 2KFWA 2Q5AA 2N87A 3JYJA 4W9PA 1Q6HA 4U85A 3O5GA 2F21A 4DRJA 5HW6A 4DIPA 3UF8A 5HW8A 4R0XA 1PBKA 3JYMA 5DIUA 3KZ7A 3UI4A 1D7IA 2PBCA 3GPKA 3MDYB 4FAPA 5B8IC 2PPOA 2OFNA 3O5IA 3CGMA 1FAPA 4QT2A 2ZQVA 1BL4A 1QPLA 4QT3A 5I98A 2MLZA 5DITA 2MF9A 1EYMA 4DZ2A 2XP7A 4TW6A 4DRNA 2ZQUA 4LAVA 5J6EA 1EQ3A 2KO7A 3KAFA 2XPBA 2VN1A 5DIVA 2RUCA 3O5OA 1FKTA 4ODLA 3O5PA 3O5MA 1KT0A 2ZQSA 2PV3A 2XP4A 5HW7A 3KACA 4GIVA 2M1IA 4JFLA 2PV2A 2XP6A 4DZ3A 3UQBA 1JNSA 2Y78A
chains in the Genus database with same CATH superfamily
3O5DA 1E15A 1FKKA 1QZ2A 3O5LA 5HKGA 4AY1A 4NZCA 1Q6UA 4MAVA 3QOKA 4U84A 1J6YA 4IT6A 1W26A 1F40A 1E9LA 1ZK6A 3B9EA 2ZR6A 4IT4A 5BXJA 1E6RA 2PN0A 2F23A 2F2DA 3B9AA 1N1AA 4DROA 2MPHA 2UZ5A 1ZU8A 1LL6A 2F4EA 3BXWA 4ITZA 3UI5A 1HJVA 2XP9A 1FKBA 1UR8A 3WH0A 4DWSC 3ARQA 4MNLA 1D6OA 3KCEA 3WD0A 1GPFA 1WB0A 1FD9A 2D9FA 4DRHA 4KR0B 4NNRA 3FY1A 2K8IA 3WD4A 2A3AA 1XRVA 4DRIA 4G2PA 4WIWA 1ITXA 4HBEA 3AS1A 5HT1A 1JNDA 2VCDA 1H0GA 3LUOA 4Z2KA 3WD1A 1A7XA 1LJYA 1IX5A 3WD3A 4C02B 4ZPWR 1FKFA 1W1PA 3AQUA 4PTMA 3IKGA 1TCOC 2Q5AA 4U85A 5HW6A 1SYTA 3UI4A 1JNEA 3GPKA 2OLHA 2ZQVA 3ARYA 5I98A 5DITA 4Z2LA 2MF9A 2XP7A 2ZQUA 4WKHA 2XPBA 3O5OA 1HJWA 3PRAA 1KT0A 2ETNA 2ZQSA 1EHNA 2PV3A 4Z2GA 4GIVA 4JFLA 2XP6A 3BMBA 1JNSA 3IKDA 4WK9A 2P4VA 2DSVA 3NTPA 3AS0A 1Y0OA 4DH0A 1FKGA 3UQAA 3O5KA 1D7JA 3O5EA 4WJXA 1BKFA 4P8VA 1HKJA 3CHEA 3I6CA 3AS3A 4Q22A 5DO2A 3NRKA 1NMVA 4JFKA 4W9OA 1FKSA 4IQCA 1NSGA 4DWSB 3GTYX 3CHFA 1ZL1A 2WM0A 4DRQA 2FAPA 4DRPA 4MSPA 2XP3A 2PI6A 1PINA 3IHZA 2M2AA 1YW5A 2RQSA 1FKDA 2ITKA 1FKLA 2KGJA 2WK2A 1J4RA 1HKIA 4IQ2A 1NWSA 3VAWA 3ARRA 3RM4A 4JYSA 1FFQA 1WAWA 2KE0A 1HKKA 3ARVA 1K9TA 3PRDA 1L1PA 4Z2IA 4WKFA 5HUAA 4BF8A 3ARWA 3GU0A 4W5UA 4FN2A 5HWBA 1OGGA 3WL0A 4MPKA 3ODKA 2KI3A 2PPPA 1B6CA 1ZCNA 1FKRA 2G41A 2EULA 1ROTA 2DT2A 3RGCA 3OA5A 1W1VA 3NI6A 3B8SA 1JVWA 3TCZA 2O9OA 5JH8A 5D75A 1RD6A 4JFJA 2LJ4A 1W1TA 1LL7A 2N87A 4W9PA 2F21A 4DIPA 3MDYB 2PBCA 4QZVB 2PPOA 3CGMA 4QT2A 1BL4A 3G6LA 4HARA 1EYMA 4TW6A 4DRNA 4LAVA 2KO7A 1FKTA 2DSZA 2XP4A 5HW7A 3KACA 2M1IA 4L72B 1W9VA 3CH9A 1UR9A 3UQBA 1KFWA 3O5PA 1Q1CA 3PR9A 3KAGA 1U79A 3ALGA 3TC5A 1ZBCA 4MNJA 2LKNA 4MTVA 4TYOA 1SR0A 3ARSA 3CGNA 2XP8A 1W9UA 1LG2A 3RM9A 2DSWA 4DRMA 3OOBA 1E44A 4TNSA 2XP5A 2DPEA 1CTNA 3ARUA 4DWSA 3EIPA 2A3BA 4MGVA 1F8AB 4Q7NA 1M5YA 3O5FA 1GRJA 4U86A 2LGOA 2YBUA 3WQWA 3PA7A 1X6NA 2ZR4A 4TW8A 1E6NA 1LL4A 4QIBA 2IUZA 3O5RA 5HBFA 2A3CA 4LAYA 2QF8A 1Q6IA 1ZBWA 4W9QA 3AS2A 5HTGA 4N19A 4DRKA 1NWUA 3KAHA 2DT0A 2RURA 3CHCA 1ZBKA 3TDBA 1W1YA 3H9RB 3WQVA 1E6PA 1C9HA 2B5UB 1D7HA 4LGXA 3FAPA 2JZVA 4LAWA 1HKMA 4J4OA 4ZS6A 4P8XA 4S3KA 2KFWA 1Q6HA 3O5GA 3CHDA 4Z2JA 3UF8A 4R0XA 1PBKA 4L3NA 5DIUA 3KZ7A 1D7IA 5B8IC 4FAPA 2G8ZA 2OFNA 3O5IA 1FAPA 5DEZA 5GQBA 4MNMA 1GUVA 3ARXA 4NSBA 1EQ3A 3ARZA 1OWQA 3O5MA 1TFVA 1NH6A 4ML4A 4DZ3A 3W4RA 1P5QA 4GGQA 2ESCA 4Z2HA 1FKJA 3RMEA 4P8UA 4JFMA 4ODRA 4MNKA 4ZPTR 1ROUA 1NWTA 4UDMA 4ZPVR 2WLZA 2DSUA 3CZ8A 4URIA 5DF0A 3KAIA 3PRBA 3O5JA 1KT1A 2PV1A 1LQ0A 3FXYA 1J4IA 4IPXA 2PPNA 2YBTA 2ZQTA 2RUQA 2M08A 1QPFA 3ARTA 3KADA 4KQZA 4ODNA 5GPGA 2ZR5A 1FJDA 4J4NA 4TX0A 3B7XA 2DT1A 1H0IA 1HXVA 1LG1A 1FFRA 2DG3A 3IK8A 3UI6A 1EIBA 2XPAA 2MLXA 4G50A 4DWSD 1FKIA 4ODOA 2DG4A 2LPVA 3WD2A 4DT4A 4ODPA 2DT3A 3ALFA 1NMWA 1R9HA 4ODMA 1T11A 1VF8A 4S3JA 1JCHB 1EDQA 1ZB5A 2DG9A 4JFIA 1O6IA 2AWGA 4R5EA 2FDMA 1XHGA 3RFWA 1WNOA 2IF4A 5HWCA 2RUDA 4ODKA 4ODQA 3EY6A 1HJXA 2FKEA 2MLYA 1J4HA 1ZBVA 2L2SA 4TW7A 4WKAA 4HBOA 1E6ZA 3JXVA 4XAKA 2RSEA 3G6MA 3RM8A 2O92A 3UQIA 1JNTA 4LAXA 1YATA 3KABA 4O2TA 2WLYA 2MNTA 3O5QA 1FKHA 2KR7A 1GOIA 3JYJA 3WL1A 4DRJA 5HW8A 3JYMA 3WKZA 2A3EA 1NWRA 1QPLA 4P8WA 4QT3A 2B31A 1X6LA 2MLZA 4DZ2A 2AOSA 5J6EA 1D2KA 3KAFA 5DIVA 2VN1A 3AROA 2RUCA 1OGBA 3B9DA 4ODLA 3ARPA 1W9PA 2PV2A 5GPRA 3WIJA 2Y78A
chains in the Genus database with same CATH topology
3O5DA 1E15A 1FKKA 1QZ2A 3O5LA 5HKGA 4AY1A 4NZCA 1Q6UA 4MAVA 3QOKA 4U84A 1J6YA 4IT6A 1W26A 1F40A 1E9LA 1ZK6A 3B9EA 2ZR6A 4IT4A 5BXJA 1E6RA 2F2DA 3B9AA 1N1AA 4DROA 2MPHA 2UZ5A 1ZU8A 1LL6A 2F4EA 3BXWA 4ITZA 3UI5A 1HJVA 2XP9A 1FKBA 1UR8A 3WH0A 4DWSC 3ARQA 4MNLA 1D6OA 3KCEA 3WD0A 1GPFA 1WB0A 1FD9A 2D9FA 4DRHA 4KR0B 4NNRA 3FY1A 2K8IA 3WD4A 2A3AA 1XRVA 4DRIA 4G2PA 4WIWA 1ITXA 4HBEA 3AS1A 5HT1A 1JNDA 2VCDA 1H0GA 3LUOA 4Z2KA 3WD1A 1A7XA 1LJYA 1IX5A 3WD3A 4C02B 4ZPWR 1FKFA 1W1PA 3AQUA 4PTMA 3IKGA 1TCOC 2Q5AA 4U85A 5HW6A 1SYTA 3UI4A 1JNEA 3GPKA 2OLHA 2ZQVA 3ARYA 5I98A 5DITA 4Z2LA 2MF9A 2XP7A 2ZQUA 4WKHA 2XPBA 3O5OA 1HJWA 3PRAA 1KT0A 2ZQSA 1EHNA 2PV3A 4Z2GA 4GIVA 4JFLA 2XP6A 1JNSA 3IKDA 4WK9A 2DSVA 3NTPA 3AS0A 1Y0OA 4DH0A 1FKGA 3UQAA 3O5KA 1D7JA 3O5EA 4WJXA 1BKFA 4P8VA 1HKJA 3CHEA 3I6CA 3AS3A 4Q22A 5DO2A 3NRKA 1NMVA 4JFKA 4W9OA 1FKSA 4IQCA 1NSGA 4DWSB 3CHFA 1ZL1A 2WM0A 4DRQA 2FAPA 4DRPA 4MSPA 2XP3A 2PI6A 1PINA 3IHZA 2M2AA 1YW5A 2RQSA 1FKDA 2ITKA 1FKLA 2KGJA 2WK2A 1J4RA 1HKIA 4IQ2A 1NWSA 3VAWA 3ARRA 3RM4A 4JYSA 1FFQA 1WAWA 2KE0A 1HKKA 3ARVA 1K9TA 3PRDA 1L1PA 4Z2IA 4WKFA 5HUAA 4BF8A 3ARWA 4W5UA 4FN2A 5HWBA 1OGGA 3WL0A 4MPKA 3ODKA 2KI3A 2PPPA 1B6CA 1ZCNA 1FKRA 2G41A 1ROTA 2DT2A 3RGCA 3OA5A 1W1VA 3NI6A 3B8SA 1JVWA 3TCZA 2O9OA 5JH8A 5D75A 1RD6A 4JFJA 2LJ4A 1W1TA 1LL7A 2N87A 4W9PA 2F21A 4DIPA 3MDYB 2PBCA 4QZVB 2PPOA 3CGMA 4QT2A 1BL4A 3G6LA 4HARA 1EYMA 4TW6A 4DRNA 4LAVA 2KO7A 1FKTA 2DSZA 2XP4A 5HW7A 3KACA 2M1IA 4L72B 1W9VA 3CH9A 1UR9A 3UQBA 1KFWA 3O5PA 1Q1CA 3PR9A 3KAGA 1U79A 3ALGA 3TC5A 1ZBCA 4MNJA 2LKNA 4MTVA 4TYOA 1SR0A 3ARSA 3CGNA 2XP8A 1W9UA 1LG2A 3RM9A 2DSWA 4DRMA 3OOBA 4TNSA 2XP5A 2DPEA 1CTNA 3ARUA 4DWSA 2A3BA 4MGVA 1F8AB 4Q7NA 1M5YA 3O5FA 4U86A 2LGOA 2YBUA 3WQWA 3PA7A 1X6NA 2ZR4A 4TW8A 1E6NA 1LL4A 4QIBA 2IUZA 3O5RA 5HBFA 2A3CA 4LAYA 1Q6IA 1ZBWA 2QF8A 4W9QA 3AS2A 5HTGA 4N19A 4DRKA 1NWUA 3KAHA 2DT0A 2RURA 3CHCA 1ZBKA 3TDBA 1W1YA 3H9RB 3WQVA 1E6PA 1C9HA 1D7HA 4LGXA 3FAPA 2JZVA 4LAWA 1HKMA 4J4OA 4ZS6A 4P8XA 4S3KA 2KFWA 1Q6HA 3O5GA 3CHDA 4Z2JA 3UF8A 4R0XA 1PBKA 4L3NA 5DIUA 3KZ7A 1D7IA 5B8IC 4FAPA 2G8ZA 2OFNA 3O5IA 1FAPA 5DEZA 5GQBA 4MNMA 1GUVA 3ARXA 4NSBA 1EQ3A 3ARZA 1OWQA 3O5MA 1TFVA 1NH6A 4ML4A 4DZ3A 3W4RA 1P5QA 4GGQA 2ESCA 4Z2HA 1FKJA 3RMEA 4P8UA 4JFMA 4ODRA 4MNKA 4ZPTR 1ROUA 1NWTA 4ZPVR 2WLZA 2DSUA 3CZ8A 4URIA 5DF0A 3KAIA 3PRBA 3O5JA 1KT1A 2PV1A 1LQ0A 3FXYA 1J4IA 4IPXA 2PPNA 2YBTA 2ZQTA 2RUQA 2M08A 1QPFA 3ARTA 3KADA 4KQZA 4ODNA 5GPGA 2ZR5A 1FJDA 4J4NA 4TX0A 3B7XA 2DT1A 1H0IA 1HXVA 1LG1A 1FFRA 2DG3A 3IK8A 3UI6A 1EIBA 2XPAA 2MLXA 4G50A 4DWSD 1FKIA 4ODOA 2DG4A 2LPVA 3WD2A 4DT4A 4ODPA 2DT3A 3ALFA 1NMWA 1R9HA 4ODMA 1T11A 1VF8A 4S3JA 1EDQA 1ZB5A 2DG9A 4JFIA 1O6IA 2AWGA 4R5EA 2FDMA 1XHGA 3RFWA 1WNOA 2IF4A 5HWCA 2RUDA 4ODKA 4ODQA 3EY6A 1HJXA 2FKEA 2MLYA 1J4HA 1ZBVA 2L2SA 4TW7A 4WKAA 4HBOA 1E6ZA 3JXVA 4XAKA 2RSEA 3G6MA 3RM8A 2O92A 3UQIA 1JNTA 4LAXA 1YATA 3KABA 4O2TA 2WLYA 2MNTA 3O5QA 1FKHA 2KR7A 1GOIA 3JYJA 3WL1A 4DRJA 5HW8A 3JYMA 3WKZA 2A3EA 1NWRA 1QPLA 4P8WA 4QT3A 2B31A 1X6LA 2MLZA 4DZ2A 2AOSA 5J6EA 1D2KA 3KAFA 5DIVA 2VN1A 3AROA 2RUCA 1OGBA 3B9DA 4ODLA 3ARPA 1W9PA 2PV2A 5GPRA 3WIJA 2Y78A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3O5D A;  1P5Q A;  1Q1C A;  4GGQ A;  3KAG A;  1U79 A;  3NTP A;  1Y0O A;  1FKK A;  4DH0 A;  3TC5 A;  1FKG A;  3UQA A;  1QZ2 A;  1FKJ A;  2LKN A;  3O5K A;  1D7J A;  3O5E A;  4JFM A;  4ODR A;  4TYO A;  3CGN A;  1BKF A;  1ROU A;  2XP8 A;  3I6C A;  3O5L A;  5HKG A;  3KAI A;  3NRK A;  1Q6U A;  3OOB A;  1NMV A;  3PRB A;  4DRM A;  3O5J A;  4JFK A;  1KT1 A;  4TNS A;  2PV1 A;  2XP5 A;  4U84 A;  4IPX A;  1J4I A;  4W9O A;  1J6Y A;  2PPN A;  1FKS A;  2ZQT A;  1W26 A;  2RUQ A;  4IQC A;  1NSG A;  1F40 A;  2M08 A;  1QPF A;  1ZK6 A;  2ZR6 A;  3KAD A;  5GPG A;  4ODN A;  2ZR5 A;  4DRQ A;  5BXJ A;  2FAP A;  4MGV A;  4DRP A;  2F2D A;  1F8A B;  4MSP A;  2XP3 A;  1M5Y A;  1FJD A;  3O5F A;  1PIN A;  4J4N A;  3B7X A;  4TX0 A;  3IHZ A;  4U86 A;  1N1A A;  4DRO A;  2M2A A;  2LGO A;  1HXV A;  1YW5 A;  2MPH A;  2RQS A;  2UZ5 A;  1FKD A;  2ITK A;  2DG3 A;  1FKL A;  3IK8 A;  3UI6 A;  3PA7 A;  2KGJ A;  4ITZ A;  2F4E A;  2XPA A;  3UI5 A;  2MLX A;  1J4R A;  4G50 A;  2ZR4 A;  1FKI A;  4TW8 A;  2XP9 A;  1FKB A;  4ODO A;  4QIB A;  2DG4 A;  2LPV A;  3IKD A;  4IQ2 A;  4ODP A;  4DT4 A;  3WH0 A;  3VAW A;  3O5R A;  1NMW A;  1R9H A;  1D6O A;  3KCE A;  4LAY A;  4ODM A;  1Q6I A;  1T11 A;  4W9Q A;  1FD9 A;  2DG9 A;  4JFI A;  2AWG A;  2D9F A;  5HTG A;  4DRH A;  4JYS A;  3RFW A;  2KE0 A;  4NNR A;  4N19 A;  4DRK A;  3PRD A;  2IF4 A;  1L1P A;  5HUA A;  2K8I A;  4BF8 A;  2RUD A;  3KAH A;  4ODK A;  5HWC A;  4FN2 A;  4ODQ A;  3EY6 A;  2RUR A;  2FKE A;  2MLY A;  1J4H A;  5HWB A;  3TDB A;  4DRI A;  2L2S A;  4G2P A;  3ODK A;  3H9R B;  2KI3 A;  2PPP A;  1B6C A;  1ZCN A;  4TW7 A;  1FKR A;  1ROT A;  3JXV A;  5HT1 A;  1C9H A;  2RSE A;  2VCD A;  3RGC A;  1D7H A;  3LUO A;  3UQI A;  1JNT A;  4LAX A;  1A7X A;  1YAT A;  3KAB A;  3NI6 A;  4O2T A;  1JVW A;  3TCZ A;  2MNT A;  2JZV A;  3FAP A;  4LAW A;  4C02 B;  3O5Q A;  5D75 A;  4J4O A;  4JFJ A;  1FKF A;  1FKH A;  2LJ4 A;  2KR7 A;  3IKG A;  1TCO C;  2KFW A;  2Q5A A;  2N87 A;  3JYJ A;  4W9P A;  1Q6H A;  4U85 A;  3O5G A;  2F21 A;  4DRJ A;  5HW6 A;  4DIP A;  3UF8 A;  5HW8 A;  4R0X A;  1PBK A;  3JYM A;  5DIU A;  3KZ7 A;  3UI4 A;  1D7I A;  2PBC A;  3GPK A;  3MDY B;  4FAP A;  5B8I C;  2PPO A;  2OFN A;  3O5I A;  3CGM A;  1FAP A;  4QT2 A;  2ZQV A;  1BL4 A;  1QPL A;  4QT3 A;  5I98 A;  2MLZ A;  5DIT A;  2MF9 A;  1EYM A;  4DZ2 A;  2XP7 A;  4TW6 A;  4DRN A;  2ZQU A;  4LAV A;  5J6E A;  1EQ3 A;  2KO7 A;  3KAF A;  2XPB A;  2VN1 A;  5DIV A;  2RUC A;  3O5O A;  1FKT A;  4ODL A;  3O5P A;  3O5M A;  1KT0 A;  2ZQS A;  2PV3 A;  2XP4 A;  5HW7 A;  3KAC A;  4GIV A;  2M1I A;  4JFL A;  2PV2 A;  2XP6 A;  4DZ3 A;  3UQB A;  1JNS A;  2Y78 A; 
#chains in the Genus database with same CATH topology
 3O5D A;  1E15 A;  1FKK A;  1QZ2 A;  3O5L A;  5HKG A;  4AY1 A;  4NZC A;  1Q6U A;  4MAV A;  3QOK A;  4U84 A;  1J6Y A;  4IT6 A;  1W26 A;  1F40 A;  1E9L A;  1ZK6 A;  3B9E A;  2ZR6 A;  4IT4 A;  5BXJ A;  1E6R A;  2PN0 A;  2F23 A;  2F2D A;  3B9A A;  1N1A A;  4DRO A;  2MPH A;  2UZ5 A;  1ZU8 A;  1LL6 A;  2F4E A;  3BXW A;  4ITZ A;  3UI5 A;  1HJV A;  2XP9 A;  1FKB A;  1UR8 A;  3WH0 A;  4DWS C;  3ARQ A;  4MNL A;  1D6O A;  3KCE A;  3WD0 A;  1GPF A;  1WB0 A;  1FD9 A;  2D9F A;  4DRH A;  4KR0 B;  4NNR A;  3FY1 A;  2K8I A;  3WD4 A;  2A3A A;  1XRV A;  4DRI A;  4G2P A;  4WIW A;  1ITX A;  4HBE A;  3AS1 A;  5HT1 A;  1JND A;  2VCD A;  1H0G A;  3LUO A;  4Z2K A;  3WD1 A;  1A7X A;  1LJY A;  1IX5 A;  3WD3 A;  4C02 B;  4ZPW R;  1FKF A;  1W1P A;  3AQU A;  4PTM A;  3IKG A;  1TCO C;  2Q5A A;  4U85 A;  5HW6 A;  1SYT A;  3UI4 A;  1JNE A;  3GPK A;  2OLH A;  2ZQV A;  3ARY A;  5I98 A;  5DIT A;  4Z2L A;  2MF9 A;  2XP7 A;  2ZQU A;  4WKH A;  2XPB A;  3O5O A;  1HJW A;  3PRA A;  1KT0 A;  2ETN A;  2ZQS A;  1EHN A;  2PV3 A;  4Z2G A;  4GIV A;  4JFL A;  2XP6 A;  3BMB A;  1JNS A;  3IKD A;  4WK9 A;  2P4V A;  2DSV A;  3NTP A;  3AS0 A;  1Y0O A;  4DH0 A;  1FKG A;  3UQA A;  3O5K A;  1D7J A;  3O5E A;  4WJX A;  1BKF A;  4P8V A;  1HKJ A;  3CHE A;  3I6C A;  3AS3 A;  4Q22 A;  5DO2 A;  3NRK A;  1NMV A;  4JFK A;  4W9O A;  1FKS A;  4IQC A;  1NSG A;  4DWS B;  3GTY X;  3CHF A;  1ZL1 A;  2WM0 A;  4DRQ A;  2FAP A;  4DRP A;  4MSP A;  2XP3 A;  2PI6 A;  1PIN A;  3IHZ A;  2M2A A;  1YW5 A;  2RQS A;  1FKD A;  2ITK A;  1FKL A;  2KGJ A;  2WK2 A;  1J4R A;  1HKI A;  4IQ2 A;  1NWS A;  3VAW A;  3ARR A;  3RM4 A;  4JYS A;  1FFQ A;  1WAW A;  2KE0 A;  1HKK A;  3ARV A;  1K9T A;  3PRD A;  1L1P A;  4Z2I A;  4WKF A;  5HUA A;  4BF8 A;  3ARW A;  3GU0 A;  4W5U A;  4FN2 A;  5HWB A;  1OGG A;  3WL0 A;  4MPK A;  3ODK A;  2KI3 A;  2PPP A;  1B6C A;  1ZCN A;  1FKR A;  2G41 A;  2EUL A;  1ROT A;  2DT2 A;  3RGC A;  3OA5 A;  1W1V A;  3NI6 A;  3B8S A;  1JVW A;  3TCZ A;  2O9O A;  5JH8 A;  5D75 A;  1RD6 A;  4JFJ A;  2LJ4 A;  1W1T A;  1LL7 A;  2N87 A;  4W9P A;  2F21 A;  4DIP A;  3MDY B;  2PBC A;  4QZV B;  2PPO A;  3CGM A;  4QT2 A;  1BL4 A;  3G6L A;  4HAR A;  1EYM A;  4TW6 A;  4DRN A;  4LAV A;  2KO7 A;  1FKT A;  2DSZ A;  2XP4 A;  5HW7 A;  3KAC A;  2M1I A;  4L72 B;  1W9V A;  3CH9 A;  1UR9 A;  3UQB A;  1KFW A;  3O5P A;  1Q1C A;  3PR9 A;  3KAG A;  1U79 A;  3ALG A;  3TC5 A;  1ZBC A;  4MNJ A;  2LKN A;  4MTV A;  4TYO A;  1SR0 A;  3ARS A;  3CGN A;  2XP8 A;  1W9U A;  1LG2 A;  3RM9 A;  2DSW A;  4DRM A;  3OOB A;  1E44 A;  4TNS A;  2XP5 A;  2DPE A;  1CTN A;  3ARU A;  4DWS A;  3EIP A;  2A3B A;  4MGV A;  1F8A B;  4Q7N A;  1M5Y A;  3O5F A;  1GRJ A;  4U86 A;  2LGO A;  2YBU A;  3WQW A;  3PA7 A;  1X6N A;  2ZR4 A;  4TW8 A;  1E6N A;  1LL4 A;  4QIB A;  2IUZ A;  3O5R A;  5HBF A;  2A3C A;  4LAY A;  2QF8 A;  1Q6I A;  1ZBW A;  4W9Q A;  3AS2 A;  5HTG A;  4N19 A;  4DRK A;  1NWU A;  3KAH A;  2DT0 A;  2RUR A;  3CHC A;  1ZBK A;  3TDB A;  1W1Y A;  3H9R B;  3WQV A;  1E6P A;  1C9H A;  2B5U B;  1D7H A;  4LGX A;  3FAP A;  2JZV A;  4LAW A;  1HKM A;  4J4O A;  4ZS6 A;  4P8X A;  4S3K A;  2KFW A;  1Q6H A;  3O5G A;  3CHD A;  4Z2J A;  3UF8 A;  4R0X A;  1PBK A;  4L3N A;  5DIU A;  3KZ7 A;  1D7I A;  5B8I C;  4FAP A;  2G8Z A;  2OFN A;  3O5I A;  1FAP A;  5DEZ A;  5GQB A;  4MNM A;  1GUV A;  3ARX A;  4NSB A;  1EQ3 A;  3ARZ A;  1OWQ A;  3O5M A;  1TFV A;  1NH6 A;  4ML4 A;  4DZ3 A;  3W4R A;  1P5Q A;  4GGQ A;  2ESC A;  4Z2H A;  1FKJ A;  3RME A;  4P8U A;  4JFM A;  4ODR A;  4MNK A;  4ZPT R;  1ROU A;  1NWT A;  4UDM A;  4ZPV R;  2WLZ A;  2DSU A;  3CZ8 A;  4URI A;  5DF0 A;  3KAI A;  3PRB A;  3O5J A;  1KT1 A;  2PV1 A;  1LQ0 A;  3FXY A;  1J4I A;  4IPX A;  2PPN A;  2YBT A;  2ZQT A;  2RUQ A;  2M08 A;  1QPF A;  3ART A;  3KAD A;  4KQZ A;  4ODN A;  5GPG A;  2ZR5 A;  1FJD A;  4J4N A;  4TX0 A;  3B7X A;  2DT1 A;  1H0I A;  1HXV A;  1LG1 A;  1FFR A;  2DG3 A;  3IK8 A;  3UI6 A;  1EIB A;  2XPA A;  2MLX A;  4G50 A;  4DWS D;  1FKI A;  4ODO A;  2DG4 A;  2LPV A;  3WD2 A;  4DT4 A;  4ODP A;  2DT3 A;  3ALF A;  1NMW A;  1R9H A;  4ODM A;  1T11 A;  1VF8 A;  4S3J A;  1JCH B;  1EDQ A;  1ZB5 A;  2DG9 A;  4JFI A;  1O6I A;  2AWG A;  4R5E A;  2FDM A;  1XHG A;  3RFW A;  1WNO A;  2IF4 A;  5HWC A;  2RUD A;  4ODK A;  4ODQ A;  3EY6 A;  1HJX A;  2FKE A;  2MLY A;  1J4H A;  1ZBV A;  2L2S A;  4TW7 A;  4WKA A;  4HBO A;  1E6Z A;  3JXV A;  4XAK A;  2RSE A;  3G6M A;  3RM8 A;  2O92 A;  3UQI A;  1JNT A;  4LAX A;  1YAT A;  3KAB A;  4O2T A;  2WLY A;  2MNT A;  3O5Q A;  1FKH A;  2KR7 A;  1GOI A;  3JYJ A;  3WL1 A;  4DRJ A;  5HW8 A;  3JYM A;  3WKZ A;  2A3E A;  1NWR A;  1QPL A;  4P8W A;  4QT3 A;  2B31 A;  1X6L A;  2MLZ A;  4DZ2 A;  2AOS A;  5J6E A;  1D2K A;  3KAF A;  5DIV A;  2VN1 A;  3ARO A;  2RUC A;  1OGB A;  3B9D A;  4ODL A;  3ARP A;  1W9P A;  2PV2 A;  5GPR A;  3WIJ A;  2Y78 A; 
#chains in the Genus database with same CATH homology
 3O5D A;  1E15 A;  1FKK A;  1QZ2 A;  3O5L A;  5HKG A;  4AY1 A;  4NZC A;  1Q6U A;  4MAV A;  3QOK A;  4U84 A;  1J6Y A;  4IT6 A;  1W26 A;  1F40 A;  1E9L A;  1ZK6 A;  3B9E A;  2ZR6 A;  4IT4 A;  5BXJ A;  1E6R A;  2F2D A;  3B9A A;  1N1A A;  4DRO A;  2MPH A;  2UZ5 A;  1ZU8 A;  1LL6 A;  2F4E A;  3BXW A;  4ITZ A;  3UI5 A;  1HJV A;  2XP9 A;  1FKB A;  1UR8 A;  3WH0 A;  4DWS C;  3ARQ A;  4MNL A;  1D6O A;  3KCE A;  3WD0 A;  1GPF A;  1WB0 A;  1FD9 A;  2D9F A;  4DRH A;  4KR0 B;  4NNR A;  3FY1 A;  2K8I A;  3WD4 A;  2A3A A;  1XRV A;  4DRI A;  4G2P A;  4WIW A;  1ITX A;  4HBE A;  3AS1 A;  5HT1 A;  1JND A;  2VCD A;  1H0G A;  3LUO A;  4Z2K A;  3WD1 A;  1A7X A;  1LJY A;  1IX5 A;  3WD3 A;  4C02 B;  4ZPW R;  1FKF A;  1W1P A;  3AQU A;  4PTM A;  3IKG A;  1TCO C;  2Q5A A;  4U85 A;  5HW6 A;  1SYT A;  3UI4 A;  1JNE A;  3GPK A;  2OLH A;  2ZQV A;  3ARY A;  5I98 A;  5DIT A;  4Z2L A;  2MF9 A;  2XP7 A;  2ZQU A;  4WKH A;  2XPB A;  3O5O A;  1HJW A;  3PRA A;  1KT0 A;  2ZQS A;  1EHN A;  2PV3 A;  4Z2G A;  4GIV A;  4JFL A;  2XP6 A;  1JNS A;  3IKD A;  4WK9 A;  2DSV A;  3NTP A;  3AS0 A;  1Y0O A;  4DH0 A;  1FKG A;  3UQA A;  3O5K A;  1D7J A;  3O5E A;  4WJX A;  1BKF A;  4P8V A;  1HKJ A;  3CHE A;  3I6C A;  3AS3 A;  4Q22 A;  5DO2 A;  3NRK A;  1NMV A;  4JFK A;  4W9O A;  1FKS A;  4IQC A;  1NSG A;  4DWS B;  3CHF A;  1ZL1 A;  2WM0 A;  4DRQ A;  2FAP A;  4DRP A;  4MSP A;  2XP3 A;  2PI6 A;  1PIN A;  3IHZ A;  2M2A A;  1YW5 A;  2RQS A;  1FKD A;  2ITK A;  1FKL A;  2KGJ A;  2WK2 A;  1J4R A;  1HKI A;  4IQ2 A;  1NWS A;  3VAW A;  3ARR A;  3RM4 A;  4JYS A;  1FFQ A;  1WAW A;  2KE0 A;  1HKK A;  3ARV A;  1K9T A;  3PRD A;  1L1P A;  4Z2I A;  4WKF A;  5HUA A;  4BF8 A;  3ARW A;  4W5U A;  4FN2 A;  5HWB A;  1OGG A;  3WL0 A;  4MPK A;  3ODK A;  2KI3 A;  2PPP A;  1B6C A;  1ZCN A;  1FKR A;  2G41 A;  1ROT A;  2DT2 A;  3RGC A;  3OA5 A;  1W1V A;  3NI6 A;  3B8S A;  1JVW A;  3TCZ A;  2O9O A;  5JH8 A;  5D75 A;  1RD6 A;  4JFJ A;  2LJ4 A;  1W1T A;  1LL7 A;  2N87 A;  4W9P A;  2F21 A;  4DIP A;  3MDY B;  2PBC A;  4QZV B;  2PPO A;  3CGM A;  4QT2 A;  1BL4 A;  3G6L A;  4HAR A;  1EYM A;  4TW6 A;  4DRN A;  4LAV A;  2KO7 A;  1FKT A;  2DSZ A;  2XP4 A;  5HW7 A;  3KAC A;  2M1I A;  4L72 B;  1W9V A;  3CH9 A;  1UR9 A;  3UQB A;  1KFW A;  3O5P A;  1Q1C A;  3PR9 A;  3KAG A;  1U79 A;  3ALG A;  3TC5 A;  1ZBC A;  4MNJ A;  2LKN A;  4MTV A;  4TYO A;  1SR0 A;  3ARS A;  3CGN A;  2XP8 A;  1W9U A;  1LG2 A;  3RM9 A;  2DSW A;  4DRM A;  3OOB A;  4TNS A;  2XP5 A;  2DPE A;  1CTN A;  3ARU A;  4DWS A;  2A3B A;  4MGV A;  1F8A B;  4Q7N A;  1M5Y A;  3O5F A;  4U86 A;  2LGO A;  2YBU A;  3WQW A;  3PA7 A;  1X6N A;  2ZR4 A;  4TW8 A;  1E6N A;  1LL4 A;  4QIB A;  2IUZ A;  3O5R A;  5HBF A;  2A3C A;  4LAY A;  1Q6I A;  1ZBW A;  2QF8 A;  4W9Q A;  3AS2 A;  5HTG A;  4N19 A;  4DRK A;  1NWU A;  3KAH A;  2DT0 A;  2RUR A;  3CHC A;  1ZBK A;  3TDB A;  1W1Y A;  3H9R B;  3WQV A;  1E6P A;  1C9H A;  1D7H A;  4LGX A;  3FAP A;  2JZV A;  4LAW A;  1HKM A;  4J4O A;  4ZS6 A;  4P8X A;  4S3K A;  2KFW A;  1Q6H A;  3O5G A;  3CHD A;  4Z2J A;  3UF8 A;  4R0X A;  1PBK A;  4L3N A;  5DIU A;  3KZ7 A;  1D7I A;  5B8I C;  4FAP A;  2G8Z A;  2OFN A;  3O5I A;  1FAP A;  5DEZ A;  5GQB A;  4MNM A;  1GUV A;  3ARX A;  4NSB A;  1EQ3 A;  3ARZ A;  1OWQ A;  3O5M A;  1TFV A;  1NH6 A;  4ML4 A;  4DZ3 A;  3W4R A;  1P5Q A;  4GGQ A;  2ESC A;  4Z2H A;  1FKJ A;  3RME A;  4P8U A;  4JFM A;  4ODR A;  4MNK A;  4ZPT R;  1ROU A;  1NWT A;  4ZPV R;  2WLZ A;  2DSU A;  3CZ8 A;  4URI A;  5DF0 A;  3KAI A;  3PRB A;  3O5J A;  1KT1 A;  2PV1 A;  1LQ0 A;  3FXY A;  1J4I A;  4IPX A;  2PPN A;  2YBT A;  2ZQT A;  2RUQ A;  2M08 A;  1QPF A;  3ART A;  3KAD A;  4KQZ A;  4ODN A;  5GPG A;  2ZR5 A;  1FJD A;  4J4N A;  4TX0 A;  3B7X A;  2DT1 A;  1H0I A;  1HXV A;  1LG1 A;  1FFR A;  2DG3 A;  3IK8 A;  3UI6 A;  1EIB A;  2XPA A;  2MLX A;  4G50 A;  4DWS D;  1FKI A;  4ODO A;  2DG4 A;  2LPV A;  3WD2 A;  4DT4 A;  4ODP A;  2DT3 A;  3ALF A;  1NMW A;  1R9H A;  4ODM A;  1T11 A;  1VF8 A;  4S3J A;  1EDQ A;  1ZB5 A;  2DG9 A;  4JFI A;  1O6I A;  2AWG A;  4R5E A;  2FDM A;  1XHG A;  3RFW A;  1WNO A;  2IF4 A;  5HWC A;  2RUD A;  4ODK A;  4ODQ A;  3EY6 A;  1HJX A;  2FKE A;  2MLY A;  1J4H A;  1ZBV A;  2L2S A;  4TW7 A;  4WKA A;  4HBO A;  1E6Z A;  3JXV A;  4XAK A;  2RSE A;  3G6M A;  3RM8 A;  2O92 A;  3UQI A;  1JNT A;  4LAX A;  1YAT A;  3KAB A;  4O2T A;  2WLY A;  2MNT A;  3O5Q A;  1FKH A;  2KR7 A;  1GOI A;  3JYJ A;  3WL1 A;  4DRJ A;  5HW8 A;  3JYM A;  3WKZ A;  2A3E A;  1NWR A;  1QPL A;  4P8W A;  4QT3 A;  2B31 A;  1X6L A;  2MLZ A;  4DZ2 A;  2AOS A;  5J6E A;  1D2K A;  3KAF A;  5DIV A;  2VN1 A;  3ARO A;  2RUC A;  1OGB A;  3B9D A;  4ODL A;  3ARP A;  1W9P A;  2PV2 A;  5GPR A;  3WIJ A;  2Y78 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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