4DH0A

X-ray crystal structure of 28-o-methylrapamycin complexed with fkbp12: is the cyclohexyl moiety part of the effector domain of rapamycin?
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
107
structure length
107
Chain Sequence
GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray Crystal Structure of 28-O-Methylrapamycin complexed with FKBP12: Is the Cyclohexyl Moiety Part of the Effector Domain of Rapamycin?
doi rcsb
source organism Homo sapiens
molecule tags Isomerase/immunosuppressant
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP1A
total genus 26
structure length 107
sequence length 107
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2012-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00254 FKBP_C FKBP-type peptidyl-prolyl cis-trans isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.50.40 Alpha Beta Roll Chitinase A; domain 3 Chitinase A; domain 3 4dh0A00
3GPKA 2LKNA 2ZQUA 4JFMA 1T11A 1J4HA 2N87A 2RUCA 3CGMA 4G2PA 4ITZA 3FAPA 2DG3A 1Y0OA 4IPXA 1NSGA 5HWCA 4DIPA 2KFWA 4GGQA 4DRJA 2PBCA 3KAHA 4ODRA 1ZK6A 5B8IC 1QZ2A 4LAWA 1Q6IA 2ZR6A 2XP5A 3CGNA 1D6OA 1FKHA 2DG4A 2PV1A 5HT1A 4DT4A 4ODOA 5DIUA 3LUOA 3MDYB 3IK8A 5HW8A 4JFKA 2MPHA 1QPFA 1ROUA 2M08A 2ZR5A 1FAPA 2MLYA 4TYOA 4TW6A 4ODPA 2XPBA 2KO7A 2KR7A 3O5PA 4BF8A 2DG9A 3I6CA 1PINA 4MSPA 3UI5A 3O5IA 4LAVA 4LAYA 1FKRA 2RQSA 3KAIA 3PRBA 4O2TA 5HWBA 1EQ3A 4GIVA 4FN2A 1D7IA 1KT1A 4DRHA 2RSEA 2ZR4A 3KAGA 2RURA 3KABA 4IQCA 5D75A 4ODNA 1J6YA 4QT2A 3ODKA 4ODLA 2ZQSA 3RGCA 2KE0A 1FKGA 3O5EA 4JYSA 1A7XA 2K8IA 2UZ5A 1ROTA 2XPAA 3KZ7A 3NI6A 3O5DA 3OOBA 2AWGA 3PRDA 4JFJA 3TCZA 2MNTA 1JVWA 3KCEA 5DIVA 4DRPA 3JYJA 3O5JA 4NNRA 2PV3A 3JYMA 4TW7A 3NRKA 1J4RA 1Q6HA 2XP8A 4TNSA 1B6CA 4C02B 1L1PA 1F8AB 1R9HA 3TC5A 1FKIA 1F40A 1EYMA 2MLXA 2F21A 3O5GA 3KACA 2ITKA 1Q1CA 2PV2A 3B7XA 2D9FA 2LPVA 3KADA 1M5YA 2M1IA 2VN1A 4U86A 1QPLA 1FKFA 2L2SA 3UF8A 4JFLA 5HW6A 1FKLA 1HXVA 1TCOC 1JNTA 4LAXA 5J6EA 4DRQA 1PBKA 3O5MA 2JZVA 4DRKA 5HW7A 2KGJA 1NMVA 1ZCNA 3O5FA 2ZQTA 4W9OA 2ZQVA 4DRMA 4ODKA 4JFIA 4QT3A 1FJDA 1D7JA 1Q6UA 2KI3A 4DZ3A 4MGVA 3O5RA 1KT0A 3PA7A 4FAPA 1FKKA 4U84A 5HUAA 1D7HA 2F2DA 2RUDA 5BXJA 5HTGA 3O5LA 2PPNA 3IHZA 3RFWA 3UQAA 4N19A 2IF4A 1W26A 4DRIA 2XP4A 4W9PA 1U79A 2PPPA 2PPOA 4J4NA 5I98A 1BL4A 3IKGA 3JXVA 4U85A 2F4EA 4TW8A 2LJ4A 5DITA 3UI4A 1N1AA 3O5QA 5HKGA 4TX0A 4ODQA 3EY6A 2MF9A 1FKSA 1NMWA 3KAFA 1J4IA 1P5QA 4W9QA 1FKJA 1JNSA 2MLZA 2VCDA 3WH0A 1FKBA 4DRNA 2LGOA 2Y78A 1YW5A 3O5KA 3O5OA 2FAPA 2FKEA 3UQIA 3VAWA 4ODMA 1C9HA 4G50A 5GPGA 2RUQA 4DZ2A 1YATA 4R0XA 1BKFA 2XP6A 2XP9A 4IQ2A 2XP7A 4QIBA 2XP3A 3H9RB 3IKDA 2Q5AA 4J4OA 1FD9A 1FKTA 3UI6A 1FKDA 3TDBA 4DH0A 3UQBA 2OFNA 4DROA 2M2AA 3NTPA
chains in the Genus database with same CATH superfamily
1WNOA 3GPKA 2WM0A 4JFMA 4WKAA 3AS3A 4G2PA 2O92A 1GUVA 1NSGA 4KQZA 4ODRA 1ZK6A 4KR0B 4LAWA 2ZR6A 2AOSA 1D6OA 4Q7NA 2A3AA 4IT6A 5HT1A 3MDYB 1W9PA 4S3KA 1W1PA 5DO2A 1FFRA 1FFQA 2DG9A 4LAVA 1ZBVA 3AROA 1D7IA 2RSEA 2ZR4A 3KAGA 1J6YA 4ODNA 3ARRA 1FKGA 2UZ5A 3O5DA 1HKMA 3WD3A 3G6LA 4P8VA 1E6NA 4NNRA 1LQ0A 3ARTA 1J4RA 1Q6HA 3ARXA 2B31A 3WL0A 3KACA 2ITKA 1Q1CA 1H0IA 2LPVA 4MNMA 1QPLA 1FKFA 2L2SA 3ARZA 1HKKA 4AY1A 3ALFA 3O5MA 2ETNA 2ZQVA 2WK2A 1HKJA 3WQVA 4DWSD 4Z2LA 3AS1A 4DZ3A 1SR0A 4MNKA 3PA7A 1FKKA 2PN0A 2DT2A 4HBEA 3PRAA 2RUDA 4Z2GA 3IHZA 1NWTA 3WD0A 3CHFA 4N19A 4DRIA 4W9PA 4J4NA 5I98A 2F4EA 4TW8A 4DWSC 5GPRA 3WD1A 2G8ZA 1EHNA 2MF9A 3KAFA 1JNSA 1OGGA 3ARQA 3WH0A 1HJXA 4P8XA 1FKBA 3O5KA 3O5OA 1LJYA 1C9HA 1NWRA 1W9UA 2DPEA 4WKHA 5GPGA 1E6ZA 4R0XA 4NZCA 1HKIA 4DWSA 3TDBA 4DROA 4O2TA 2O9OA 4ML4A 3W4RA 2LKNA 4ZPWR 1T11A 1E9LA 4ITZA 1Y0OA 5HWCA 4DIPA 4DRJA 4GGQA 1JCHB 2OLHA 5B8IC 3AQUA 1FKHA 2PV1A 3GU0A 1JNDA 5HW8A 1UR9A 5JH8A 2ZR5A 1FAPA 2MLYA 4WKFA 2XPBA 1GPFA 3ARPA 3WKZA 1PINA 1EDQA 4GIVA 4W5UA 4MTVA 2RURA 3KABA 4QT2A 4ODLA 2ZQSA 1XHGA 3O5EA 4JYSA 3KZ7A 2XPAA 2AWGA 3TCZA 2WLZA 1LG1A 2PV3A 4ZS6A 4WIWA 3NRKA 2XP8A 3AS2A 3O5GA 1OGBA 3KADA 2VN1A 4U86A 4DRQA 4DRKA 2A3CA 1HJVA 4ODKA 4JFIA 1FJDA 3CZ8A 2KI3A 1ZB5A 1SYTA 3FXYA 3O5RA 4P8WA 4U84A 1D7HA 5HTGA 3RFWA 3UQAA 2WLYA 2XP4A 2PPPA 4DWSB 2LJ4A 5DITA 3UI4A 5HKGA 2FDMA 4ODQA 3EY6A 1FKSA 1J4IA 1FKJA 2LGOA 3CHCA 1YW5A 3ARVA 2FAPA 2FKEA 3VAWA 4MPKA 4ODMA 1X6LA 1LG2A 1BKFA 2XP6A 4IQ2A 4QIBA 3B8SA 2XP3A 2Q5AA 4J4OA 3BXWA 4DH0A 3ALGA 3WD2A 3PR9A 3WL1A 2N87A 4MAVA 2DSWA 2KFWA 1TFVA 3WD4A 2PBCA 4Z2IA 2DSZA 1QZ2A 3CGNA 4Z2HA 2A3EA 4DT4A 4ODOA 5DIUA 3LUOA 4TYOA 3CHDA 4ODPA 2KO7A 1CTNA 3I6CA 2RQSA 1H0GA 1KT1A 1RD6A 5D75A 3ODKA 1A7XA 2K8IA 3ARUA 3RMEA 3NI6A 4JFJA 1LL4A 1E15A 4DRPA 3QOKA 3O5JA 3JYMA 4Z2KA 4TNSA 1L1PA 1B6CA 1LL6A 4HARA 4C02B 1F8AB 1EYMA 2MLXA 4ZPVR 3B7XA 1E44A 2EULA 2D9FA 1M5YA 1VF8A 5HW6A 1OWQA 1TCOC 1JNTA 4LAXA 5J6EA 4MNLA 1O6IA 1NWUA 2JZVA 5HW7A 2KGJA 1ZCNA 2ZQTA 4W9OA 4DRMA 2B5UB 3EIPA 4QT3A 1D7JA 1Q6UA 3RM4A 4FAPA 1KFWA 1UR8A 5HUAA 3WIJA 5BXJA 1WAWA 2DT0A 4XAKA 3OA5A 2IF4A 1W26A 2DSVA 4MNJA 1NH6A 1U79A 2PPOA 1W1YA 3JXVA 4U85A 1X6NA 1E6PA 3O5QA 5HBFA 4TX0A 1W1VA 1NMWA 1P5QA 4W9QA 4DRNA 2YBTA 2Y78A 1NWSA 1ZBKA 3UQIA 3B9DA 4L3NA 2RUQA 4DZ2A 1YATA 4LGXA 4P8UA 2XP9A 2XP7A 1HJWA 3IKDA 4ZPTR 1FD9A 3UI6A 2A3BA 2ESCA 2OFNA 3CHEA 3UQBA 3NTPA 4L72B 2ZQUA 1J4HA 2RUCA 3CGMA 3FAPA 3RM9A 2DG3A 1E6RA 4IPXA 3KAHA 5DEZA 4Z2JA 1LL7A 1Q6IA 2XP5A 4NSBA 4WJXA 2DG4A 3IK8A 1WB0A 4JFKA 2MPHA 1QPFA 1ROUA 2M08A 4WK9A 4TW6A 4URIA 2KR7A 3O5PA 4BF8A 4MSPA 2PI6A 1XRVA 3O5IA 3UI5A 4LAYA 2G41A 1FKRA 3KAIA 3PRBA 5HWBA 1EQ3A 4FN2A 4DRHA 4IQCA 3RGCA 2KE0A 2DSUA 1ROTA 3OOBA 3GTYX 2P4VA 3PRDA 2MNTA 1JVWA 3KCEA 5DIVA 3JYJA 4TW7A 5DF0A 1ZU8A 2YBUA 4QZVB 4Q22A 1K9TA 4S3JA 1R9HA 3TC5A 1F40A 1FKIA 1JNEA 1GRJA 2F21A 2PV2A 4R5EA 2M1IA 3G6MA 1EIBA 4JFLA 3UF8A 1FKLA 1HXVA 3B9EA 1PBKA 2DT1A 2IUZA 5GQBA 3WQWA 1NMVA 3CH9A 3O5FA 1IX5A 1W9VA 1ITXA 4MGVA 1KT0A 4PTMA 3FY1A 2F2DA 3O5LA 2PPNA 3ARSA 1D2KA 3B9AA 1BL4A 3IKGA 2DT3A 1N1AA 1ZL1A 3ARWA 2MLZA 2VCDA 1W1TA 3BMBA 3RM8A 4UDMA 4IT4A 2F23A 4G50A 1ZBWA 1ZBCA 4HBOA 3AS0A 3H9RB 1FKTA 1FKDA 3ARYA 1GOIA 2M2AA 2QF8A
chains in the Genus database with same CATH topology
1WNOA 3GPKA 2WM0A 4JFMA 4WKAA 3AS3A 4G2PA 2O92A 1GUVA 1NSGA 4KQZA 4ODRA 1ZK6A 4KR0B 4LAWA 2ZR6A 2AOSA 1D6OA 4Q7NA 2A3AA 4IT6A 5HT1A 3MDYB 1W9PA 4S3KA 1W1PA 5DO2A 1FFRA 1FFQA 2DG9A 4LAVA 1ZBVA 3AROA 1D7IA 2RSEA 2ZR4A 3KAGA 1J6YA 4ODNA 3ARRA 1FKGA 2UZ5A 3O5DA 1HKMA 3WD3A 3G6LA 4P8VA 1E6NA 4NNRA 1LQ0A 3ARTA 1J4RA 1Q6HA 3ARXA 2B31A 3WL0A 3KACA 2ITKA 1Q1CA 1H0IA 2LPVA 4MNMA 1QPLA 1FKFA 2L2SA 3ARZA 1HKKA 4AY1A 3ALFA 3O5MA 2ZQVA 2WK2A 1HKJA 3WQVA 4DWSD 4Z2LA 3AS1A 4DZ3A 1SR0A 4MNKA 3PA7A 1FKKA 2DT2A 4HBEA 3PRAA 2RUDA 4Z2GA 3IHZA 1NWTA 3WD0A 3CHFA 4N19A 4DRIA 4W9PA 4J4NA 5I98A 2F4EA 4TW8A 4DWSC 5GPRA 3WD1A 2G8ZA 1EHNA 2MF9A 3KAFA 1JNSA 1OGGA 3ARQA 3WH0A 1HJXA 4P8XA 1FKBA 3O5KA 3O5OA 1LJYA 1C9HA 1NWRA 1W9UA 2DPEA 4WKHA 5GPGA 1E6ZA 4R0XA 4NZCA 1HKIA 4DWSA 3TDBA 4DROA 4O2TA 2O9OA 4ML4A 3W4RA 2LKNA 4ZPWR 1T11A 1E9LA 4ITZA 1Y0OA 5HWCA 4DIPA 4DRJA 4GGQA 2OLHA 5B8IC 3AQUA 1FKHA 2PV1A 1JNDA 5HW8A 1UR9A 5JH8A 2ZR5A 1FAPA 2MLYA 4WKFA 2XPBA 1GPFA 3ARPA 3WKZA 1PINA 1EDQA 4GIVA 4W5UA 4MTVA 2RURA 3KABA 4QT2A 4ODLA 2ZQSA 1XHGA 3O5EA 4JYSA 3KZ7A 2XPAA 2AWGA 3TCZA 2WLZA 1LG1A 2PV3A 4ZS6A 4WIWA 3NRKA 2XP8A 3AS2A 3O5GA 1OGBA 3KADA 2VN1A 4U86A 4DRQA 4DRKA 2A3CA 1HJVA 4ODKA 4JFIA 1FJDA 3CZ8A 2KI3A 1ZB5A 1SYTA 3FXYA 3O5RA 4P8WA 4U84A 1D7HA 5HTGA 3RFWA 3UQAA 2WLYA 2XP4A 2PPPA 4DWSB 2LJ4A 5DITA 3UI4A 5HKGA 2FDMA 4ODQA 3EY6A 1FKSA 1J4IA 1FKJA 2LGOA 3CHCA 1YW5A 3ARVA 2FAPA 2FKEA 3VAWA 4MPKA 4ODMA 1X6LA 1LG2A 1BKFA 2XP6A 4IQ2A 4QIBA 3B8SA 2XP3A 2Q5AA 4J4OA 3BXWA 4DH0A 3ALGA 3WD2A 3PR9A 3WL1A 2N87A 4MAVA 2DSWA 2KFWA 1TFVA 3WD4A 2PBCA 4Z2IA 2DSZA 1QZ2A 3CGNA 4Z2HA 2A3EA 4DT4A 4ODOA 5DIUA 3LUOA 4TYOA 3CHDA 4ODPA 2KO7A 1CTNA 3I6CA 2RQSA 1H0GA 1KT1A 1RD6A 5D75A 3ODKA 1A7XA 2K8IA 3ARUA 3RMEA 3NI6A 4JFJA 1LL4A 1E15A 4DRPA 3QOKA 3O5JA 3JYMA 4Z2KA 4TNSA 1L1PA 1B6CA 1LL6A 4HARA 4C02B 1F8AB 1EYMA 2MLXA 4ZPVR 3B7XA 2D9FA 1M5YA 1VF8A 5HW6A 1OWQA 1TCOC 1JNTA 4LAXA 5J6EA 4MNLA 1O6IA 1NWUA 2JZVA 5HW7A 2KGJA 1ZCNA 2ZQTA 4W9OA 4DRMA 4QT3A 1D7JA 1Q6UA 3RM4A 4FAPA 1KFWA 1UR8A 5HUAA 3WIJA 5BXJA 1WAWA 2DT0A 4XAKA 3OA5A 2IF4A 1W26A 2DSVA 4MNJA 1NH6A 1U79A 2PPOA 1W1YA 3JXVA 4U85A 1X6NA 1E6PA 3O5QA 5HBFA 4TX0A 1W1VA 1NMWA 1P5QA 4W9QA 4DRNA 2YBTA 2Y78A 1NWSA 1ZBKA 3UQIA 3B9DA 4L3NA 2RUQA 4DZ2A 1YATA 4LGXA 4P8UA 2XP9A 2XP7A 1HJWA 3IKDA 4ZPTR 1FD9A 3UI6A 2A3BA 2ESCA 2OFNA 3CHEA 3UQBA 3NTPA 4L72B 2ZQUA 1J4HA 2RUCA 3CGMA 3FAPA 3RM9A 2DG3A 1E6RA 4IPXA 3KAHA 5DEZA 4Z2JA 1LL7A 1Q6IA 2XP5A 4NSBA 4WJXA 2DG4A 3IK8A 1WB0A 4JFKA 2MPHA 1QPFA 1ROUA 2M08A 4WK9A 4TW6A 4URIA 2KR7A 3O5PA 4BF8A 4MSPA 2PI6A 1XRVA 3O5IA 3UI5A 4LAYA 2G41A 1FKRA 3KAIA 3PRBA 5HWBA 1EQ3A 4FN2A 4DRHA 4IQCA 3RGCA 2KE0A 2DSUA 1ROTA 3OOBA 3PRDA 2MNTA 1JVWA 3KCEA 5DIVA 3JYJA 4TW7A 5DF0A 1ZU8A 2YBUA 4QZVB 4Q22A 1K9TA 4S3JA 1R9HA 3TC5A 1F40A 1FKIA 1JNEA 2F21A 2PV2A 4R5EA 2M1IA 3G6MA 1EIBA 4JFLA 3UF8A 1FKLA 1HXVA 3B9EA 1PBKA 2DT1A 2IUZA 5GQBA 3WQWA 1NMVA 3CH9A 3O5FA 1IX5A 1W9VA 1ITXA 4MGVA 1KT0A 4PTMA 3FY1A 2F2DA 3O5LA 2PPNA 3ARSA 1D2KA 3B9AA 1BL4A 3IKGA 2DT3A 1N1AA 1ZL1A 3ARWA 2MLZA 2VCDA 1W1TA 3RM8A 4IT4A 4G50A 1ZBWA 1ZBCA 4HBOA 3AS0A 3H9RB 1FKTA 1FKDA 3ARYA 1GOIA 2M2AA 2QF8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GPK A;  2LKN A;  2ZQU A;  4JFM A;  1T11 A;  1J4H A;  2N87 A;  2RUC A;  3CGM A;  4G2P A;  4ITZ A;  3FAP A;  2DG3 A;  1Y0O A;  4IPX A;  1NSG A;  5HWC A;  4DIP A;  2KFW A;  4GGQ A;  4DRJ A;  2PBC A;  3KAH A;  4ODR A;  1ZK6 A;  5B8I C;  1QZ2 A;  4LAW A;  1Q6I A;  2ZR6 A;  2XP5 A;  3CGN A;  1D6O A;  1FKH A;  2DG4 A;  2PV1 A;  5HT1 A;  4DT4 A;  4ODO A;  5DIU A;  3LUO A;  3MDY B;  3IK8 A;  5HW8 A;  4JFK A;  2MPH A;  1QPF A;  1ROU A;  2M08 A;  2ZR5 A;  1FAP A;  2MLY A;  4TYO A;  4TW6 A;  4ODP A;  2XPB A;  2KO7 A;  2KR7 A;  3O5P A;  4BF8 A;  2DG9 A;  3I6C A;  1PIN A;  4MSP A;  3UI5 A;  3O5I A;  4LAV A;  4LAY A;  1FKR A;  2RQS A;  3KAI A;  3PRB A;  4O2T A;  5HWB A;  1EQ3 A;  4GIV A;  4FN2 A;  1D7I A;  1KT1 A;  4DRH A;  2RSE A;  2ZR4 A;  3KAG A;  2RUR A;  3KAB A;  4IQC A;  5D75 A;  4ODN A;  1J6Y A;  4QT2 A;  3ODK A;  4ODL A;  2ZQS A;  3RGC A;  2KE0 A;  1FKG A;  3O5E A;  4JYS A;  1A7X A;  2K8I A;  2UZ5 A;  1ROT A;  2XPA A;  3KZ7 A;  3NI6 A;  3O5D A;  3OOB A;  2AWG A;  3PRD A;  4JFJ A;  3TCZ A;  2MNT A;  1JVW A;  3KCE A;  5DIV A;  4DRP A;  3JYJ A;  3O5J A;  4NNR A;  2PV3 A;  3JYM A;  4TW7 A;  3NRK A;  1J4R A;  1Q6H A;  2XP8 A;  4TNS A;  1B6C A;  4C02 B;  1L1P A;  1F8A B;  1R9H A;  3TC5 A;  1FKI A;  1F40 A;  1EYM A;  2MLX A;  2F21 A;  3O5G A;  3KAC A;  2ITK A;  1Q1C A;  2PV2 A;  3B7X A;  2D9F A;  2LPV A;  3KAD A;  1M5Y A;  2M1I A;  2VN1 A;  4U86 A;  1QPL A;  1FKF A;  2L2S A;  3UF8 A;  4JFL A;  5HW6 A;  1FKL A;  1HXV A;  1TCO C;  1JNT A;  4LAX A;  5J6E A;  4DRQ A;  1PBK A;  3O5M A;  2JZV A;  4DRK A;  5HW7 A;  2KGJ A;  1NMV A;  1ZCN A;  3O5F A;  2ZQT A;  4W9O A;  2ZQV A;  4DRM A;  4ODK A;  4JFI A;  4QT3 A;  1FJD A;  1D7J A;  1Q6U A;  2KI3 A;  4DZ3 A;  4MGV A;  3O5R A;  1KT0 A;  3PA7 A;  4FAP A;  1FKK A;  4U84 A;  5HUA A;  1D7H A;  2F2D A;  2RUD A;  5BXJ A;  5HTG A;  3O5L A;  2PPN A;  3IHZ A;  3RFW A;  3UQA A;  4N19 A;  2IF4 A;  1W26 A;  4DRI A;  2XP4 A;  4W9P A;  1U79 A;  2PPP A;  2PPO A;  4J4N A;  5I98 A;  1BL4 A;  3IKG A;  3JXV A;  4U85 A;  2F4E A;  4TW8 A;  2LJ4 A;  5DIT A;  3UI4 A;  1N1A A;  3O5Q A;  5HKG A;  4TX0 A;  4ODQ A;  3EY6 A;  2MF9 A;  1FKS A;  1NMW A;  3KAF A;  1J4I A;  1P5Q A;  4W9Q A;  1FKJ A;  1JNS A;  2MLZ A;  2VCD A;  3WH0 A;  1FKB A;  4DRN A;  2LGO A;  2Y78 A;  1YW5 A;  3O5K A;  3O5O A;  2FAP A;  2FKE A;  3UQI A;  3VAW A;  4ODM A;  1C9H A;  4G50 A;  5GPG A;  2RUQ A;  4DZ2 A;  1YAT A;  4R0X A;  1BKF A;  2XP6 A;  2XP9 A;  4IQ2 A;  2XP7 A;  4QIB A;  2XP3 A;  3H9R B;  3IKD A;  2Q5A A;  4J4O A;  1FD9 A;  1FKT A;  3UI6 A;  1FKD A;  3TDB A;  4DH0 A;  3UQB A;  2OFN A;  4DRO A;  2M2A A;  3NTP A; 
#chains in the Genus database with same CATH topology
 1WNO A;  3GPK A;  2WM0 A;  4JFM A;  4WKA A;  3AS3 A;  4G2P A;  2O92 A;  1GUV A;  1NSG A;  4KQZ A;  4ODR A;  1ZK6 A;  4KR0 B;  4LAW A;  2ZR6 A;  2AOS A;  1D6O A;  4Q7N A;  2A3A A;  4IT6 A;  5HT1 A;  3MDY B;  1W9P A;  4S3K A;  1W1P A;  5DO2 A;  1FFR A;  1FFQ A;  2DG9 A;  4LAV A;  1ZBV A;  3ARO A;  1D7I A;  2RSE A;  2ZR4 A;  3KAG A;  1J6Y A;  4ODN A;  3ARR A;  1FKG A;  2UZ5 A;  3O5D A;  1HKM A;  3WD3 A;  3G6L A;  4P8V A;  1E6N A;  4NNR A;  1LQ0 A;  3ART A;  1J4R A;  1Q6H A;  3ARX A;  2B31 A;  3WL0 A;  3KAC A;  2ITK A;  1Q1C A;  1H0I A;  2LPV A;  4MNM A;  1QPL A;  1FKF A;  2L2S A;  3ARZ A;  1HKK A;  4AY1 A;  3ALF A;  3O5M A;  2ETN A;  2ZQV A;  2WK2 A;  1HKJ A;  3WQV A;  4DWS D;  4Z2L A;  3AS1 A;  4DZ3 A;  1SR0 A;  4MNK A;  3PA7 A;  1FKK A;  2PN0 A;  2DT2 A;  4HBE A;  3PRA A;  2RUD A;  4Z2G A;  3IHZ A;  1NWT A;  3WD0 A;  3CHF A;  4N19 A;  4DRI A;  4W9P A;  4J4N A;  5I98 A;  2F4E A;  4TW8 A;  4DWS C;  5GPR A;  3WD1 A;  2G8Z A;  1EHN A;  2MF9 A;  3KAF A;  1JNS A;  1OGG A;  3ARQ A;  3WH0 A;  1HJX A;  4P8X A;  1FKB A;  3O5K A;  3O5O A;  1LJY A;  1C9H A;  1NWR A;  1W9U A;  2DPE A;  4WKH A;  5GPG A;  1E6Z A;  4R0X A;  4NZC A;  1HKI A;  4DWS A;  3TDB A;  4DRO A;  4O2T A;  2O9O A;  4ML4 A;  3W4R A;  2LKN A;  4ZPW R;  1T11 A;  1E9L A;  4ITZ A;  1Y0O A;  5HWC A;  4DIP A;  4DRJ A;  4GGQ A;  1JCH B;  2OLH A;  5B8I C;  3AQU A;  1FKH A;  2PV1 A;  3GU0 A;  1JND A;  5HW8 A;  1UR9 A;  5JH8 A;  2ZR5 A;  1FAP A;  2MLY A;  4WKF A;  2XPB A;  1GPF A;  3ARP A;  3WKZ A;  1PIN A;  1EDQ A;  4GIV A;  4W5U A;  4MTV A;  2RUR A;  3KAB A;  4QT2 A;  4ODL A;  2ZQS A;  1XHG A;  3O5E A;  4JYS A;  3KZ7 A;  2XPA A;  2AWG A;  3TCZ A;  2WLZ A;  1LG1 A;  2PV3 A;  4ZS6 A;  4WIW A;  3NRK A;  2XP8 A;  3AS2 A;  3O5G A;  1OGB A;  3KAD A;  2VN1 A;  4U86 A;  4DRQ A;  4DRK A;  2A3C A;  1HJV A;  4ODK A;  4JFI A;  1FJD A;  3CZ8 A;  2KI3 A;  1ZB5 A;  1SYT A;  3FXY A;  3O5R A;  4P8W A;  4U84 A;  1D7H A;  5HTG A;  3RFW A;  3UQA A;  2WLY A;  2XP4 A;  2PPP A;  4DWS B;  2LJ4 A;  5DIT A;  3UI4 A;  5HKG A;  2FDM A;  4ODQ A;  3EY6 A;  1FKS A;  1J4I A;  1FKJ A;  2LGO A;  3CHC A;  1YW5 A;  3ARV A;  2FAP A;  2FKE A;  3VAW A;  4MPK A;  4ODM A;  1X6L A;  1LG2 A;  1BKF A;  2XP6 A;  4IQ2 A;  4QIB A;  3B8S A;  2XP3 A;  2Q5A A;  4J4O A;  3BXW A;  4DH0 A;  3ALG A;  3WD2 A;  3PR9 A;  3WL1 A;  2N87 A;  4MAV A;  2DSW A;  2KFW A;  1TFV A;  3WD4 A;  2PBC A;  4Z2I A;  2DSZ A;  1QZ2 A;  3CGN A;  4Z2H A;  2A3E A;  4DT4 A;  4ODO A;  5DIU A;  3LUO A;  4TYO A;  3CHD A;  4ODP A;  2KO7 A;  1CTN A;  3I6C A;  2RQS A;  1H0G A;  1KT1 A;  1RD6 A;  5D75 A;  3ODK A;  1A7X A;  2K8I A;  3ARU A;  3RME A;  3NI6 A;  4JFJ A;  1LL4 A;  1E15 A;  4DRP A;  3QOK A;  3O5J A;  3JYM A;  4Z2K A;  4TNS A;  1L1P A;  1B6C A;  1LL6 A;  4HAR A;  4C02 B;  1F8A B;  1EYM A;  2MLX A;  4ZPV R;  3B7X A;  1E44 A;  2EUL A;  2D9F A;  1M5Y A;  1VF8 A;  5HW6 A;  1OWQ A;  1TCO C;  1JNT A;  4LAX A;  5J6E A;  4MNL A;  1O6I A;  1NWU A;  2JZV A;  5HW7 A;  2KGJ A;  1ZCN A;  2ZQT A;  4W9O A;  4DRM A;  2B5U B;  3EIP A;  4QT3 A;  1D7J A;  1Q6U A;  3RM4 A;  4FAP A;  1KFW A;  1UR8 A;  5HUA A;  3WIJ A;  5BXJ A;  1WAW A;  2DT0 A;  4XAK A;  3OA5 A;  2IF4 A;  1W26 A;  2DSV A;  4MNJ A;  1NH6 A;  1U79 A;  2PPO A;  1W1Y A;  3JXV A;  4U85 A;  1X6N A;  1E6P A;  3O5Q A;  5HBF A;  4TX0 A;  1W1V A;  1NMW A;  1P5Q A;  4W9Q A;  4DRN A;  2YBT A;  2Y78 A;  1NWS A;  1ZBK A;  3UQI A;  3B9D A;  4L3N A;  2RUQ A;  4DZ2 A;  1YAT A;  4LGX A;  4P8U A;  2XP9 A;  2XP7 A;  1HJW A;  3IKD A;  4ZPT R;  1FD9 A;  3UI6 A;  2A3B A;  2ESC A;  2OFN A;  3CHE A;  3UQB A;  3NTP A;  4L72 B;  2ZQU A;  1J4H A;  2RUC A;  3CGM A;  3FAP A;  3RM9 A;  2DG3 A;  1E6R A;  4IPX A;  3KAH A;  5DEZ A;  4Z2J A;  1LL7 A;  1Q6I A;  2XP5 A;  4NSB A;  4WJX A;  2DG4 A;  3IK8 A;  1WB0 A;  4JFK A;  2MPH A;  1QPF A;  1ROU A;  2M08 A;  4WK9 A;  4TW6 A;  4URI A;  2KR7 A;  3O5P A;  4BF8 A;  4MSP A;  2PI6 A;  1XRV A;  3O5I A;  3UI5 A;  4LAY A;  2G41 A;  1FKR A;  3KAI A;  3PRB A;  5HWB A;  1EQ3 A;  4FN2 A;  4DRH A;  4IQC A;  3RGC A;  2KE0 A;  2DSU A;  1ROT A;  3OOB A;  3GTY X;  2P4V A;  3PRD A;  2MNT A;  1JVW A;  3KCE A;  5DIV A;  3JYJ A;  4TW7 A;  5DF0 A;  1ZU8 A;  2YBU A;  4QZV B;  4Q22 A;  1K9T A;  4S3J A;  1R9H A;  3TC5 A;  1F40 A;  1FKI A;  1JNE A;  1GRJ A;  2F21 A;  2PV2 A;  4R5E A;  2M1I A;  3G6M A;  1EIB A;  4JFL A;  3UF8 A;  1FKL A;  1HXV A;  3B9E A;  1PBK A;  2DT1 A;  2IUZ A;  5GQB A;  3WQW A;  1NMV A;  3CH9 A;  3O5F A;  1IX5 A;  1W9V A;  1ITX A;  4MGV A;  1KT0 A;  4PTM A;  3FY1 A;  2F2D A;  3O5L A;  2PPN A;  3ARS A;  1D2K A;  3B9A A;  1BL4 A;  3IKG A;  2DT3 A;  1N1A A;  1ZL1 A;  3ARW A;  2MLZ A;  2VCD A;  1W1T A;  3BMB A;  3RM8 A;  4UDM A;  4IT4 A;  2F23 A;  4G50 A;  1ZBW A;  1ZBC A;  4HBO A;  3AS0 A;  3H9R B;  1FKT A;  1FKD A;  3ARY A;  1GOI A;  2M2A A;  2QF8 A; 
#chains in the Genus database with same CATH homology
 1WNO A;  3GPK A;  2WM0 A;  4JFM A;  4WKA A;  3AS3 A;  4G2P A;  2O92 A;  1GUV A;  1NSG A;  4KQZ A;  4ODR A;  1ZK6 A;  4KR0 B;  4LAW A;  2ZR6 A;  2AOS A;  1D6O A;  4Q7N A;  2A3A A;  4IT6 A;  5HT1 A;  3MDY B;  1W9P A;  4S3K A;  1W1P A;  5DO2 A;  1FFR A;  1FFQ A;  2DG9 A;  4LAV A;  1ZBV A;  3ARO A;  1D7I A;  2RSE A;  2ZR4 A;  3KAG A;  1J6Y A;  4ODN A;  3ARR A;  1FKG A;  2UZ5 A;  3O5D A;  1HKM A;  3WD3 A;  3G6L A;  4P8V A;  1E6N A;  4NNR A;  1LQ0 A;  3ART A;  1J4R A;  1Q6H A;  3ARX A;  2B31 A;  3WL0 A;  3KAC A;  2ITK A;  1Q1C A;  1H0I A;  2LPV A;  4MNM A;  1QPL A;  1FKF A;  2L2S A;  3ARZ A;  1HKK A;  4AY1 A;  3ALF A;  3O5M A;  2ZQV A;  2WK2 A;  1HKJ A;  3WQV A;  4DWS D;  4Z2L A;  3AS1 A;  4DZ3 A;  1SR0 A;  4MNK A;  3PA7 A;  1FKK A;  2DT2 A;  4HBE A;  3PRA A;  2RUD A;  4Z2G A;  3IHZ A;  1NWT A;  3WD0 A;  3CHF A;  4N19 A;  4DRI A;  4W9P A;  4J4N A;  5I98 A;  2F4E A;  4TW8 A;  4DWS C;  5GPR A;  3WD1 A;  2G8Z A;  1EHN A;  2MF9 A;  3KAF A;  1JNS A;  1OGG A;  3ARQ A;  3WH0 A;  1HJX A;  4P8X A;  1FKB A;  3O5K A;  3O5O A;  1LJY A;  1C9H A;  1NWR A;  1W9U A;  2DPE A;  4WKH A;  5GPG A;  1E6Z A;  4R0X A;  4NZC A;  1HKI A;  4DWS A;  3TDB A;  4DRO A;  4O2T A;  2O9O A;  4ML4 A;  3W4R A;  2LKN A;  4ZPW R;  1T11 A;  1E9L A;  4ITZ A;  1Y0O A;  5HWC A;  4DIP A;  4DRJ A;  4GGQ A;  2OLH A;  5B8I C;  3AQU A;  1FKH A;  2PV1 A;  1JND A;  5HW8 A;  1UR9 A;  5JH8 A;  2ZR5 A;  1FAP A;  2MLY A;  4WKF A;  2XPB A;  1GPF A;  3ARP A;  3WKZ A;  1PIN A;  1EDQ A;  4GIV A;  4W5U A;  4MTV A;  2RUR A;  3KAB A;  4QT2 A;  4ODL A;  2ZQS A;  1XHG A;  3O5E A;  4JYS A;  3KZ7 A;  2XPA A;  2AWG A;  3TCZ A;  2WLZ A;  1LG1 A;  2PV3 A;  4ZS6 A;  4WIW A;  3NRK A;  2XP8 A;  3AS2 A;  3O5G A;  1OGB A;  3KAD A;  2VN1 A;  4U86 A;  4DRQ A;  4DRK A;  2A3C A;  1HJV A;  4ODK A;  4JFI A;  1FJD A;  3CZ8 A;  2KI3 A;  1ZB5 A;  1SYT A;  3FXY A;  3O5R A;  4P8W A;  4U84 A;  1D7H A;  5HTG A;  3RFW A;  3UQA A;  2WLY A;  2XP4 A;  2PPP A;  4DWS B;  2LJ4 A;  5DIT A;  3UI4 A;  5HKG A;  2FDM A;  4ODQ A;  3EY6 A;  1FKS A;  1J4I A;  1FKJ A;  2LGO A;  3CHC A;  1YW5 A;  3ARV A;  2FAP A;  2FKE A;  3VAW A;  4MPK A;  4ODM A;  1X6L A;  1LG2 A;  1BKF A;  2XP6 A;  4IQ2 A;  4QIB A;  3B8S A;  2XP3 A;  2Q5A A;  4J4O A;  3BXW A;  4DH0 A;  3ALG A;  3WD2 A;  3PR9 A;  3WL1 A;  2N87 A;  4MAV A;  2DSW A;  2KFW A;  1TFV A;  3WD4 A;  2PBC A;  4Z2I A;  2DSZ A;  1QZ2 A;  3CGN A;  4Z2H A;  2A3E A;  4DT4 A;  4ODO A;  5DIU A;  3LUO A;  4TYO A;  3CHD A;  4ODP A;  2KO7 A;  1CTN A;  3I6C A;  2RQS A;  1H0G A;  1KT1 A;  1RD6 A;  5D75 A;  3ODK A;  1A7X A;  2K8I A;  3ARU A;  3RME A;  3NI6 A;  4JFJ A;  1LL4 A;  1E15 A;  4DRP A;  3QOK A;  3O5J A;  3JYM A;  4Z2K A;  4TNS A;  1L1P A;  1B6C A;  1LL6 A;  4HAR A;  4C02 B;  1F8A B;  1EYM A;  2MLX A;  4ZPV R;  3B7X A;  2D9F A;  1M5Y A;  1VF8 A;  5HW6 A;  1OWQ A;  1TCO C;  1JNT A;  4LAX A;  5J6E A;  4MNL A;  1O6I A;  1NWU A;  2JZV A;  5HW7 A;  2KGJ A;  1ZCN A;  2ZQT A;  4W9O A;  4DRM A;  4QT3 A;  1D7J A;  1Q6U A;  3RM4 A;  4FAP A;  1KFW A;  1UR8 A;  5HUA A;  3WIJ A;  5BXJ A;  1WAW A;  2DT0 A;  4XAK A;  3OA5 A;  2IF4 A;  1W26 A;  2DSV A;  4MNJ A;  1NH6 A;  1U79 A;  2PPO A;  1W1Y A;  3JXV A;  4U85 A;  1X6N A;  1E6P A;  3O5Q A;  5HBF A;  4TX0 A;  1W1V A;  1NMW A;  1P5Q A;  4W9Q A;  4DRN A;  2YBT A;  2Y78 A;  1NWS A;  1ZBK A;  3UQI A;  3B9D A;  4L3N A;  2RUQ A;  4DZ2 A;  1YAT A;  4LGX A;  4P8U A;  2XP9 A;  2XP7 A;  1HJW A;  3IKD A;  4ZPT R;  1FD9 A;  3UI6 A;  2A3B A;  2ESC A;  2OFN A;  3CHE A;  3UQB A;  3NTP A;  4L72 B;  2ZQU A;  1J4H A;  2RUC A;  3CGM A;  3FAP A;  3RM9 A;  2DG3 A;  1E6R A;  4IPX A;  3KAH A;  5DEZ A;  4Z2J A;  1LL7 A;  1Q6I A;  2XP5 A;  4NSB A;  4WJX A;  2DG4 A;  3IK8 A;  1WB0 A;  4JFK A;  2MPH A;  1QPF A;  1ROU A;  2M08 A;  4WK9 A;  4TW6 A;  4URI A;  2KR7 A;  3O5P A;  4BF8 A;  4MSP A;  2PI6 A;  1XRV A;  3O5I A;  3UI5 A;  4LAY A;  2G41 A;  1FKR A;  3KAI A;  3PRB A;  5HWB A;  1EQ3 A;  4FN2 A;  4DRH A;  4IQC A;  3RGC A;  2KE0 A;  2DSU A;  1ROT A;  3OOB A;  3PRD A;  2MNT A;  1JVW A;  3KCE A;  5DIV A;  3JYJ A;  4TW7 A;  5DF0 A;  1ZU8 A;  2YBU A;  4QZV B;  4Q22 A;  1K9T A;  4S3J A;  1R9H A;  3TC5 A;  1F40 A;  1FKI A;  1JNE A;  2F21 A;  2PV2 A;  4R5E A;  2M1I A;  3G6M A;  1EIB A;  4JFL A;  3UF8 A;  1FKL A;  1HXV A;  3B9E A;  1PBK A;  2DT1 A;  2IUZ A;  5GQB A;  3WQW A;  1NMV A;  3CH9 A;  3O5F A;  1IX5 A;  1W9V A;  1ITX A;  4MGV A;  1KT0 A;  4PTM A;  3FY1 A;  2F2D A;  3O5L A;  2PPN A;  3ARS A;  1D2K A;  3B9A A;  1BL4 A;  3IKG A;  2DT3 A;  1N1A A;  1ZL1 A;  3ARW A;  2MLZ A;  2VCD A;  1W1T A;  3RM8 A;  4IT4 A;  4G50 A;  1ZBW A;  1ZBC A;  4HBO A;  3AS0 A;  3H9R B;  1FKT A;  1FKD A;  3ARY A;  1GOI A;  2M2A A;  2QF8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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