4DRPA

Evaluation of synthetic fk506 analogs as ligands for the fk506-binding proteins 51 and 52: complex of fkbp51 with 2-(3-((r)-3-(3,4-dimethoxyphenyl)-1-((s)-1-(2-((1r,2s)-2-ethyl-1-hydroxy-cyclohexyl)-2-oxoacetyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid from cocrystallization
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
128
structure length
128
Chain Sequence
GAPATVTEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52.
pubmed doi rcsb
molecule tags Isomerase
source organism Homo sapiens
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP5
total genus 36
structure length 128
sequence length 128
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2012-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00254 FKBP_C FKBP-type peptidyl-prolyl cis-trans isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.50.40 Alpha Beta Roll Chitinase A; domain 3 Chitinase A; domain 3 4drpA00
4DRMA 1T11A 1FKFA 1W26A 2KGJA 4DIPA 3O5IA 4ODNA 4ODOA 1FD9A 3ODKA 3KCEA 2ZQVA 4ODKA 1FKGA 2DG9A 4JFKA 1FKDA 4N19A 1EYMA 2RQSA 1YATA 2XP6A 3H9RB 3O5QA 4DROA 4DT4A 3O5GA 1ZK6A 4ITZA 4LAVA 4DRQA 2FKEA 3PRBA 4DRPA 1HXVA 3OOBA 4FN2A 2F21A 3KACA 1ZCNA 3LUOA 5HUAA 1FKTA 3KAFA 1N1AA 2MPHA 1FKKA 2ZQSA 1Q6IA 4JFLA 3IKDA 2KO7A 2ZR4A 5B8IC 5HW7A 4MSPA 3JYMA 3PA7A 4DRIA 2ZQUA 2AWGA 3O5DA 2KR7A 1QPLA 2LJ4A 2ZR6A 3O5OA 2ZQTA 4GIVA 4TX0A 5HWBA 3IK8A 4ODPA 2K8IA 1Q6HA 5GPGA 5HW8A 1L1PA 1D6OA 4U86A 1QZ2A 3NTPA 4MGVA 4W9QA 1Q6UA 1PBKA 2PBCA 4TNSA 3KAGA 5DIUA 4QT3A 1U79A 1PINA 4IQ2A 3UQAA 1F8AB 2L2SA 3NI6A 2N87A 4NNRA 2IF4A 4DRHA 2XPAA 1KT1A 4IQCA 5J6EA 1FKBA 1R9HA 2M1IA 2PV3A 2F4EA 1FAPA 2LKNA 4ODMA 2PV1A 3IHZA 3O5EA 4TW6A 4DZ3A 4GGQA 2LGOA 3VAWA 2Q5AA 2RURA 2XP9A 2MLYA 4ODLA 1FKJA 1D7HA 3CGNA 5BXJA 5I98A 4LAXA 4J4NA 2FAPA 2ITKA 2M2AA 3TC5A 4TW8A 3O5LA 1M5YA 1J4HA 3I6CA 3KAHA 2KI3A 4LAWA 3O5FA 3UI6A 3KZ7A 3B7XA 2UZ5A 5HKGA 1J6YA 1KT0A 1FKSA 3RGCA 1QPFA 2PV2A 1EQ3A 2DG3A 2RUCA 3UI4A 2DG4A 1D7IA 2MF9A 3JXVA 4DH0A 2OFNA 1J4IA 4G50A 4JFIA 1ROTA 2RUDA 1Y0OA 1F40A 4O2TA 2MLZA 4BF8A 3TCZA 1C9HA 2PPPA 2XP3A 3KADA 4U84A 1J4RA 5HW6A 1Q1CA 3KABA 5HTGA 4W9PA 4DZ2A 3O5PA 2Y78A 3O5KA 4J4OA 4TW7A 4U85A 2ZR5A 2PPOA 2PPNA 2RSEA 5HT1A 3UI5A 1YW5A 1BL4A 2JZVA 3MDYB 3O5JA 4R0XA 3UQBA 3O5MA 3UQIA 2LPVA 4DRNA 4JFMA 1FKIA 3UF8A 2D9FA 1FKHA 2XP8A 1BKFA 1FJDA 4DRKA 3NRKA 1NMWA 4C02B 1TCOC 1FKLA 2F2DA 1JNSA 5DIVA 4G2PA 4ODQA 2XP4A 4W9OA 3EY6A 4QT2A 5DITA 3GPKA 3IKGA 3TDBA 4DRJA 4LAYA 2MLXA 4TYOA 2VCDA 2KFWA 2XP5A 2XPBA 3CGMA 5D75A 1P5QA 4FAPA 3RFWA 4IPXA 1NSGA 2RUQA 2VN1A 3O5RA 4JFJA 4QIBA 3KAIA 1A7XA 1JVWA 2KE0A 2MNTA 4JYSA 1FKRA 1B6CA 1D7JA 4ODRA 3WH0A 3JYJA 5HWCA 1NMVA 1ROUA 2XP7A 1JNTA 2M08A 3PRDA 3FAPA
chains in the Genus database with same CATH superfamily
1W26A 2KGJA 1LG2A 4ODNA 3ODKA 2ZQVA 4P8VA 1FKGA 1W1YA 2DG9A 1FKDA 4NSBA 4N19A 1EYMA 2RQSA 1YATA 3H9RB 4P8XA 3ARZA 3O5GA 4DRQA 4Z2LA 2P4VA 2FKEA 4XAKA 1UR9A 3OOBA 2F21A 5HUAA 1FKTA 2DSWA 3CHEA 2ZQSA 1FKKA 1SYTA 2DSUA 4Q7NA 1NWRA 4DRIA 5HBFA 2AWGA 1NWSA 2ZR6A 2B31A 4PTMA 1E6RA 1UR8A 2ETNA 2K8IA 4Z2HA 1PBKA 4WK9A 4IQ2A 3WKZA 4DRHA 2XPAA 1ZU8A 4IQCA 4KR0B 1R9HA 4ODMA 4DZ3A 4MTVA 3VAWA 2RURA 4ZS6A 1ZL1A 4NZCA 1JCHB 3TC5A 1E6ZA 1W1TA 3I6CA 3O5FA 3UI6A 2UZ5A 3RMEA 3ARVA 3UI4A 2DG4A 1D7IA 2OFNA 1ITXA 2EULA 2G41A 1D2KA 1LJYA 1Q1CA 4IT6A 4L72B 2Y78A 4MAVA 3O5JA 3ARWA 3O5MA 3UQIA 1ZBVA 3WD1A 4MPKA 1XHGA 3AROA 3NRKA 1NMWA 4C02B 1TCOC 2F2DA 1JNSA 4G2PA 1O6IA 1HKJA 2XP4A 1ZBKA 3GPKA 4AY1A 3CGMA 5D75A 3ARUA 3RFWA 4IPXA 3RM9A 2DT3A 3ARTA 2VN1A 3O5RA 1W9UA 2FDMA 3KAIA 1FKRA 1B6CA 4ODRA 1NMVA 1ROUA 1SR0A 3FAPA 4ODOA 4QZVB 2B5UB 4ODKA 4JFKA 1E44A 3O5QA 4DT4A 3PRAA 4MNJA 4FN2A 3KACA 5JH8A 4JFLA 3B9DA 5HW7A 1E9LA 3PA7A 1E15A 1W9PA 2ZQUA 3GU0A 3O5DA 2KR7A 3WD4A 2ZQTA 5HWBA 1Q6HA 5GPGA 5HW8A 1D6OA 4MGVA 1LL7A 3KAGA 4QT3A 2O92A 1EHNA 3NI6A 3WQWA 4Z2IA 1KT1A 5J6EA 3GTYX 3CH9A 5GPRA 2M1IA 2LKNA 3O5EA 3RM8A 2LGOA 2A3CA 3CGNA 4LAXA 2FAPA 1GOIA 3ARRA 1E6PA 1J6YA 3WIJA 1QPFA 2PV2A 2DG3A 2MF9A 1H0GA 4JFIA 1OWQA 1ROTA 2RUDA 1Y0OA 4Q22A 3ALGA 4P8UA 2PI6A 2MLZA 1FFRA 4BF8A 4Z2GA 1C9HA 2PPPA 2XP3A 3KADA 4U84A 1J4RA 4DWSA 2IUZA 3KABA 5HTGA 4W9PA 3O5PA 4MNLA 3UI5A 2RSEA 2DT1A 1YW5A 3MDYB 4DRNA 2DT0A 1FKIA 1BKFA 5DO2A 1VF8A 4MNKA 2WLYA 4ODQA 1XRVA 4LAYA 2MLXA 1HKKA 3ARXA 4TYOA 2VCDA 2XP5A 2XPBA 3CHFA 1P5QA 1WB0A 4QIBA 4DWSD 1JVWA 3WH0A 5HWCA 3JYJA 2XP7A 4R5EA 1CTNA 2M08A 1LG1A 3PRDA 4DRMA 1FKFA 4DIPA 1NWTA 3O5IA 3FY1A 4HARA 1FD9A 2WM0A 3PR9A 2YBTA 1OGBA 3BXWA 4DROA 1HJVA 4LAVA 4ITZA 3PRBA 1HXVA 3ALFA 3LUOA 4ML4A 1IX5A 3KAFA 5DF0A 1N1AA 2MPHA 5B8IC 3WD2A 2KO7A 2ZR4A 1HJWA 4MSPA 3JYMA 2LJ4A 4GIVA 2DPEA 4WIWA 3IK8A 4ODPA 3AS1A 3ARQA 1L1PA 1QZ2A 3NTPA 4P8WA 1LQ0A 1Q6UA 2PBCA 5GQBA 1X6LA 5DIUA 3UQAA 1EDQA 2G8ZA 2N87A 4NNRA 2IF4A 1NWUA 1LL6A 2PV3A 2F4EA 1FAPA 3CHDA 3B9EA 3IHZA 4GGQA 5DEZA 2DSZA 4ODLA 2XP9A 2MLYA 5BXJA 1FKJA 5I98A 4L3NA 4ZPVR 4J4NA 2M2AA 1TFVA 1J4HA 5HKGA 1WAWA 1X6NA 2RUCA 3JXVA 2DT2A 1J4IA 4G50A 1F40A 4Z2JA 3RM4A 4DWSB 5HW6A 1JNDA 4W5UA 1ZBCA 3WQVA 4J4OA 4TW7A 2ZR5A 2A3EA 5HT1A 4R0XA 3AS2A 3UQBA 3W4RA 2LPVA 1K9TA 3UF8A 2D9FA 2XP8A 1HKIA 4WJXA 1ZB5A 1GPFA 1HKMA 3WD3A 1FKLA 5DIVA 3G6MA 1GRJA 4W9OA 4QT2A 3IKGA 3TDBA 4DRJA 4FAPA 4URIA 2A3BA 3B8SA 1A7XA 2PN0A 2MNTA 1EIBA 1H0IA 3ARSA 3ARPA 4JYSA 1JNTA 1T11A 3KCEA 4IT4A 1W9VA 2XP6A 1ZK6A 1KFWA 4DWSC 4LGXA 2AOSA 2A3AA 4DRPA 1ZCNA 3CHCA 1Q6IA 4KQZA 3IKDA 3AS0A 3WL1A 1OGGA 3O5OA 1QPLA 2ESCA 4TX0A 4U86A 4W9QA 1RD6A 4HBOA 4TNSA 1WNOA 1U79A 1PINA 1F8AB 2L2SA 2YBUA 3B9AA 3EIPA 1FKBA 2O9OA 3G6LA 4TW6A 2PV1A 2DSVA 1JNEA 4WKFA 2Q5AA 1ZBWA 1D7HA 2F23A 2ITKA 4TW8A 3O5LA 1M5YA 1E6NA 3KAHA 2KI3A 4LAWA 3KZ7A 3QOKA 3B7XA 1KT0A 1FKSA 3RGCA 1W1PA 1EQ3A 4HBEA 4ZPWR 4DH0A 4ZPTR 2WLZA 4O2TA 2OLHA 3TCZA 1NH6A 4DZ2A 4WKAA 3O5KA 4U85A 2PPOA 2PPNA 2QF8A 2JZVA 1BL4A 4JFMA 1FKHA 3OA5A 4S3KA 1FJDA 4DRKA 4MNMA 3WL0A 3WD0A 2WK2A 1FFQA 3EY6A 1GUVA 4Z2KA 3FXYA 4S3JA 3AQUA 2KFWA 1HJXA 3CZ8A 4UDMA 4WKHA 1NSGA 3BMBA 1W1VA 2RUQA 4JFJA 2KE0A 1LL4A 3AS3A 1D7JA 3ARYA 5DITA
chains in the Genus database with same CATH topology
1W26A 2KGJA 1LG2A 4ODNA 3ODKA 2ZQVA 4P8VA 1FKGA 1W1YA 2DG9A 1FKDA 4NSBA 4N19A 1EYMA 2RQSA 1YATA 3H9RB 4P8XA 3ARZA 3O5GA 4DRQA 4Z2LA 2FKEA 4XAKA 1UR9A 3OOBA 2F21A 5HUAA 1FKTA 2DSWA 3CHEA 2ZQSA 1FKKA 1SYTA 2DSUA 4Q7NA 1NWRA 4DRIA 5HBFA 2AWGA 1NWSA 2ZR6A 2B31A 4PTMA 1E6RA 1UR8A 2K8IA 4Z2HA 1PBKA 4WK9A 4IQ2A 3WKZA 4DRHA 2XPAA 1ZU8A 4IQCA 4KR0B 1R9HA 4ODMA 4DZ3A 4MTVA 3VAWA 2RURA 4ZS6A 1ZL1A 4NZCA 3TC5A 1E6ZA 1W1TA 3I6CA 3O5FA 3UI6A 2UZ5A 3RMEA 3ARVA 3UI4A 2DG4A 1D7IA 2OFNA 1ITXA 2G41A 1D2KA 1LJYA 1Q1CA 4IT6A 4L72B 2Y78A 4MAVA 3O5JA 3ARWA 3O5MA 3UQIA 1ZBVA 3WD1A 4MPKA 1XHGA 3AROA 3NRKA 1NMWA 4C02B 1TCOC 2F2DA 1JNSA 4G2PA 1O6IA 1HKJA 2XP4A 1ZBKA 3GPKA 4AY1A 3CGMA 5D75A 3ARUA 3RFWA 4IPXA 3RM9A 2DT3A 3ARTA 2VN1A 3O5RA 1W9UA 2FDMA 3KAIA 1FKRA 1B6CA 4ODRA 1NMVA 1ROUA 1SR0A 3FAPA 4ODOA 4QZVB 4ODKA 4JFKA 3O5QA 4DT4A 3PRAA 4MNJA 4FN2A 3KACA 5JH8A 4JFLA 3B9DA 5HW7A 1E9LA 3PA7A 1E15A 1W9PA 2ZQUA 3O5DA 2KR7A 3WD4A 2ZQTA 5HWBA 1Q6HA 5GPGA 5HW8A 1D6OA 4MGVA 1LL7A 3KAGA 4QT3A 2O92A 1EHNA 3NI6A 3WQWA 4Z2IA 1KT1A 5J6EA 3CH9A 5GPRA 2M1IA 2LKNA 3O5EA 3RM8A 2LGOA 2A3CA 3CGNA 4LAXA 2FAPA 1GOIA 3ARRA 1E6PA 1J6YA 3WIJA 1QPFA 2PV2A 2DG3A 2MF9A 1H0GA 4JFIA 1OWQA 1ROTA 2RUDA 1Y0OA 4Q22A 3ALGA 4P8UA 2PI6A 2MLZA 1FFRA 4BF8A 4Z2GA 1C9HA 2PPPA 2XP3A 3KADA 4U84A 1J4RA 4DWSA 2IUZA 3KABA 5HTGA 4W9PA 3O5PA 4MNLA 3UI5A 2RSEA 2DT1A 1YW5A 3MDYB 4DRNA 2DT0A 1FKIA 1BKFA 5DO2A 1VF8A 4MNKA 2WLYA 4ODQA 1XRVA 4LAYA 2MLXA 1HKKA 3ARXA 4TYOA 2VCDA 2XP5A 2XPBA 3CHFA 1P5QA 1WB0A 4QIBA 4DWSD 1JVWA 3WH0A 5HWCA 3JYJA 2XP7A 4R5EA 1CTNA 2M08A 1LG1A 3PRDA 4DRMA 1FKFA 4DIPA 1NWTA 3O5IA 3FY1A 4HARA 1FD9A 2WM0A 3PR9A 2YBTA 1OGBA 3BXWA 4DROA 1HJVA 4LAVA 4ITZA 3PRBA 1HXVA 3ALFA 3LUOA 4ML4A 1IX5A 3KAFA 5DF0A 1N1AA 2MPHA 5B8IC 3WD2A 2KO7A 2ZR4A 1HJWA 4MSPA 3JYMA 2LJ4A 4GIVA 2DPEA 4WIWA 3IK8A 4ODPA 3AS1A 3ARQA 1L1PA 1QZ2A 3NTPA 4P8WA 1LQ0A 1Q6UA 2PBCA 5GQBA 1X6LA 5DIUA 3UQAA 1EDQA 2G8ZA 2N87A 4NNRA 2IF4A 1NWUA 1LL6A 2PV3A 2F4EA 1FAPA 3CHDA 3B9EA 3IHZA 4GGQA 5DEZA 2DSZA 4ODLA 2XP9A 2MLYA 5BXJA 1FKJA 5I98A 4L3NA 4ZPVR 4J4NA 2M2AA 1TFVA 1J4HA 5HKGA 1WAWA 1X6NA 2RUCA 3JXVA 2DT2A 1J4IA 4G50A 1F40A 4Z2JA 3RM4A 4DWSB 5HW6A 1JNDA 4W5UA 1ZBCA 3WQVA 4J4OA 4TW7A 2ZR5A 2A3EA 5HT1A 4R0XA 3AS2A 3UQBA 3W4RA 2LPVA 1K9TA 3UF8A 2D9FA 2XP8A 1HKIA 4WJXA 1ZB5A 1GPFA 1HKMA 3WD3A 1FKLA 5DIVA 3G6MA 4W9OA 4QT2A 3IKGA 3TDBA 4DRJA 4FAPA 4URIA 2A3BA 3B8SA 1A7XA 2MNTA 1EIBA 1H0IA 3ARSA 3ARPA 4JYSA 1JNTA 1T11A 3KCEA 4IT4A 1W9VA 2XP6A 1ZK6A 1KFWA 4DWSC 4LGXA 2AOSA 2A3AA 4DRPA 1ZCNA 3CHCA 1Q6IA 4KQZA 3IKDA 3AS0A 3WL1A 1OGGA 3O5OA 1QPLA 2ESCA 4TX0A 4U86A 4W9QA 1RD6A 4HBOA 4TNSA 1WNOA 1U79A 1PINA 1F8AB 2L2SA 2YBUA 3B9AA 1FKBA 2O9OA 3G6LA 4TW6A 2PV1A 2DSVA 1JNEA 4WKFA 2Q5AA 1ZBWA 1D7HA 2ITKA 4TW8A 3O5LA 1M5YA 1E6NA 3KAHA 2KI3A 4LAWA 3KZ7A 3QOKA 3B7XA 1KT0A 1FKSA 3RGCA 1W1PA 1EQ3A 4HBEA 4ZPWR 4DH0A 4ZPTR 2WLZA 4O2TA 2OLHA 3TCZA 1NH6A 4DZ2A 4WKAA 3O5KA 4U85A 2PPOA 2PPNA 2QF8A 2JZVA 1BL4A 4JFMA 1FKHA 3OA5A 4S3KA 1FJDA 4DRKA 4MNMA 3WL0A 3WD0A 2WK2A 1FFQA 3EY6A 1GUVA 4Z2KA 3FXYA 4S3JA 3AQUA 2KFWA 1HJXA 3CZ8A 4WKHA 1NSGA 1W1VA 2RUQA 4JFJA 2KE0A 1LL4A 3AS3A 1D7JA 3ARYA 5DITA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DRM A;  1T11 A;  1FKF A;  1W26 A;  2KGJ A;  4DIP A;  3O5I A;  4ODN A;  4ODO A;  1FD9 A;  3ODK A;  3KCE A;  2ZQV A;  4ODK A;  1FKG A;  2DG9 A;  4JFK A;  1FKD A;  4N19 A;  1EYM A;  2RQS A;  1YAT A;  2XP6 A;  3H9R B;  3O5Q A;  4DRO A;  4DT4 A;  3O5G A;  1ZK6 A;  4ITZ A;  4LAV A;  4DRQ A;  2FKE A;  3PRB A;  4DRP A;  1HXV A;  3OOB A;  4FN2 A;  2F21 A;  3KAC A;  1ZCN A;  3LUO A;  5HUA A;  1FKT A;  3KAF A;  1N1A A;  2MPH A;  1FKK A;  2ZQS A;  1Q6I A;  4JFL A;  3IKD A;  2KO7 A;  2ZR4 A;  5B8I C;  5HW7 A;  4MSP A;  3JYM A;  3PA7 A;  4DRI A;  2ZQU A;  2AWG A;  3O5D A;  2KR7 A;  1QPL A;  2LJ4 A;  2ZR6 A;  3O5O A;  2ZQT A;  4GIV A;  4TX0 A;  5HWB A;  3IK8 A;  4ODP A;  2K8I A;  1Q6H A;  5GPG A;  5HW8 A;  1L1P A;  1D6O A;  4U86 A;  1QZ2 A;  3NTP A;  4MGV A;  4W9Q A;  1Q6U A;  1PBK A;  2PBC A;  4TNS A;  3KAG A;  5DIU A;  4QT3 A;  1U79 A;  1PIN A;  4IQ2 A;  3UQA A;  1F8A B;  2L2S A;  3NI6 A;  2N87 A;  4NNR A;  2IF4 A;  4DRH A;  2XPA A;  1KT1 A;  4IQC A;  5J6E A;  1FKB A;  1R9H A;  2M1I A;  2PV3 A;  2F4E A;  1FAP A;  2LKN A;  4ODM A;  2PV1 A;  3IHZ A;  3O5E A;  4TW6 A;  4DZ3 A;  4GGQ A;  2LGO A;  3VAW A;  2Q5A A;  2RUR A;  2XP9 A;  2MLY A;  4ODL A;  1FKJ A;  1D7H A;  3CGN A;  5BXJ A;  5I98 A;  4LAX A;  4J4N A;  2FAP A;  2ITK A;  2M2A A;  3TC5 A;  4TW8 A;  3O5L A;  1M5Y A;  1J4H A;  3I6C A;  3KAH A;  2KI3 A;  4LAW A;  3O5F A;  3UI6 A;  3KZ7 A;  3B7X A;  2UZ5 A;  5HKG A;  1J6Y A;  1KT0 A;  1FKS A;  3RGC A;  1QPF A;  2PV2 A;  1EQ3 A;  2DG3 A;  2RUC A;  3UI4 A;  2DG4 A;  1D7I A;  2MF9 A;  3JXV A;  4DH0 A;  2OFN A;  1J4I A;  4G50 A;  4JFI A;  1ROT A;  2RUD A;  1Y0O A;  1F40 A;  4O2T A;  2MLZ A;  4BF8 A;  3TCZ A;  1C9H A;  2PPP A;  2XP3 A;  3KAD A;  4U84 A;  1J4R A;  5HW6 A;  1Q1C A;  3KAB A;  5HTG A;  4W9P A;  4DZ2 A;  3O5P A;  2Y78 A;  3O5K A;  4J4O A;  4TW7 A;  4U85 A;  2ZR5 A;  2PPO A;  2PPN A;  2RSE A;  5HT1 A;  3UI5 A;  1YW5 A;  1BL4 A;  2JZV A;  3MDY B;  3O5J A;  4R0X A;  3UQB A;  3O5M A;  3UQI A;  2LPV A;  4DRN A;  4JFM A;  1FKI A;  3UF8 A;  2D9F A;  1FKH A;  2XP8 A;  1BKF A;  1FJD A;  4DRK A;  3NRK A;  1NMW A;  4C02 B;  1TCO C;  1FKL A;  2F2D A;  1JNS A;  5DIV A;  4G2P A;  4ODQ A;  2XP4 A;  4W9O A;  3EY6 A;  4QT2 A;  5DIT A;  3GPK A;  3IKG A;  3TDB A;  4DRJ A;  4LAY A;  2MLX A;  4TYO A;  2VCD A;  2KFW A;  2XP5 A;  2XPB A;  3CGM A;  5D75 A;  1P5Q A;  4FAP A;  3RFW A;  4IPX A;  1NSG A;  2RUQ A;  2VN1 A;  3O5R A;  4JFJ A;  4QIB A;  3KAI A;  1A7X A;  1JVW A;  2KE0 A;  2MNT A;  4JYS A;  1FKR A;  1B6C A;  1D7J A;  4ODR A;  3WH0 A;  3JYJ A;  5HWC A;  1NMV A;  1ROU A;  2XP7 A;  1JNT A;  2M08 A;  3PRD A;  3FAP A; 
#chains in the Genus database with same CATH topology
 1W26 A;  2KGJ A;  1LG2 A;  4ODN A;  3ODK A;  2ZQV A;  4P8V A;  1FKG A;  1W1Y A;  2DG9 A;  1FKD A;  4NSB A;  4N19 A;  1EYM A;  2RQS A;  1YAT A;  3H9R B;  4P8X A;  3ARZ A;  3O5G A;  4DRQ A;  4Z2L A;  2P4V A;  2FKE A;  4XAK A;  1UR9 A;  3OOB A;  2F21 A;  5HUA A;  1FKT A;  2DSW A;  3CHE A;  2ZQS A;  1FKK A;  1SYT A;  2DSU A;  4Q7N A;  1NWR A;  4DRI A;  5HBF A;  2AWG A;  1NWS A;  2ZR6 A;  2B31 A;  4PTM A;  1E6R A;  1UR8 A;  2ETN A;  2K8I A;  4Z2H A;  1PBK A;  4WK9 A;  4IQ2 A;  3WKZ A;  4DRH A;  2XPA A;  1ZU8 A;  4IQC A;  4KR0 B;  1R9H A;  4ODM A;  4DZ3 A;  4MTV A;  3VAW A;  2RUR A;  4ZS6 A;  1ZL1 A;  4NZC A;  1JCH B;  3TC5 A;  1E6Z A;  1W1T A;  3I6C A;  3O5F A;  3UI6 A;  2UZ5 A;  3RME A;  3ARV A;  3UI4 A;  2DG4 A;  1D7I A;  2OFN A;  1ITX A;  2EUL A;  2G41 A;  1D2K A;  1LJY A;  1Q1C A;  4IT6 A;  4L72 B;  2Y78 A;  4MAV A;  3O5J A;  3ARW A;  3O5M A;  3UQI A;  1ZBV A;  3WD1 A;  4MPK A;  1XHG A;  3ARO A;  3NRK A;  1NMW A;  4C02 B;  1TCO C;  2F2D A;  1JNS A;  4G2P A;  1O6I A;  1HKJ A;  2XP4 A;  1ZBK A;  3GPK A;  4AY1 A;  3CGM A;  5D75 A;  3ARU A;  3RFW A;  4IPX A;  3RM9 A;  2DT3 A;  3ART A;  2VN1 A;  3O5R A;  1W9U A;  2FDM A;  3KAI A;  1FKR A;  1B6C A;  4ODR A;  1NMV A;  1ROU A;  1SR0 A;  3FAP A;  4ODO A;  4QZV B;  2B5U B;  4ODK A;  4JFK A;  1E44 A;  3O5Q A;  4DT4 A;  3PRA A;  4MNJ A;  4FN2 A;  3KAC A;  5JH8 A;  4JFL A;  3B9D A;  5HW7 A;  1E9L A;  3PA7 A;  1E15 A;  1W9P A;  2ZQU A;  3GU0 A;  3O5D A;  2KR7 A;  3WD4 A;  2ZQT A;  5HWB A;  1Q6H A;  5GPG A;  5HW8 A;  1D6O A;  4MGV A;  1LL7 A;  3KAG A;  4QT3 A;  2O92 A;  1EHN A;  3NI6 A;  3WQW A;  4Z2I A;  1KT1 A;  5J6E A;  3GTY X;  3CH9 A;  5GPR A;  2M1I A;  2LKN A;  3O5E A;  3RM8 A;  2LGO A;  2A3C A;  3CGN A;  4LAX A;  2FAP A;  1GOI A;  3ARR A;  1E6P A;  1J6Y A;  3WIJ A;  1QPF A;  2PV2 A;  2DG3 A;  2MF9 A;  1H0G A;  4JFI A;  1OWQ A;  1ROT A;  2RUD A;  1Y0O A;  4Q22 A;  3ALG A;  4P8U A;  2PI6 A;  2MLZ A;  1FFR A;  4BF8 A;  4Z2G A;  1C9H A;  2PPP A;  2XP3 A;  3KAD A;  4U84 A;  1J4R A;  4DWS A;  2IUZ A;  3KAB A;  5HTG A;  4W9P A;  3O5P A;  4MNL A;  3UI5 A;  2RSE A;  2DT1 A;  1YW5 A;  3MDY B;  4DRN A;  2DT0 A;  1FKI A;  1BKF A;  5DO2 A;  1VF8 A;  4MNK A;  2WLY A;  4ODQ A;  1XRV A;  4LAY A;  2MLX A;  1HKK A;  3ARX A;  4TYO A;  2VCD A;  2XP5 A;  2XPB A;  3CHF A;  1P5Q A;  1WB0 A;  4QIB A;  4DWS D;  1JVW A;  3WH0 A;  5HWC A;  3JYJ A;  2XP7 A;  4R5E A;  1CTN A;  2M08 A;  1LG1 A;  3PRD A;  4DRM A;  1FKF A;  4DIP A;  1NWT A;  3O5I A;  3FY1 A;  4HAR A;  1FD9 A;  2WM0 A;  3PR9 A;  2YBT A;  1OGB A;  3BXW A;  4DRO A;  1HJV A;  4LAV A;  4ITZ A;  3PRB A;  1HXV A;  3ALF A;  3LUO A;  4ML4 A;  1IX5 A;  3KAF A;  5DF0 A;  1N1A A;  2MPH A;  5B8I C;  3WD2 A;  2KO7 A;  2ZR4 A;  1HJW A;  4MSP A;  3JYM A;  2LJ4 A;  4GIV A;  2DPE A;  4WIW A;  3IK8 A;  4ODP A;  3AS1 A;  3ARQ A;  1L1P A;  1QZ2 A;  3NTP A;  4P8W A;  1LQ0 A;  1Q6U A;  2PBC A;  5GQB A;  1X6L A;  5DIU A;  3UQA A;  1EDQ A;  2G8Z A;  2N87 A;  4NNR A;  2IF4 A;  1NWU A;  1LL6 A;  2PV3 A;  2F4E A;  1FAP A;  3CHD A;  3B9E A;  3IHZ A;  4GGQ A;  5DEZ A;  2DSZ A;  4ODL A;  2XP9 A;  2MLY A;  5BXJ A;  1FKJ A;  5I98 A;  4L3N A;  4ZPV R;  4J4N A;  2M2A A;  1TFV A;  1J4H A;  5HKG A;  1WAW A;  1X6N A;  2RUC A;  3JXV A;  2DT2 A;  1J4I A;  4G50 A;  1F40 A;  4Z2J A;  3RM4 A;  4DWS B;  5HW6 A;  1JND A;  4W5U A;  1ZBC A;  3WQV A;  4J4O A;  4TW7 A;  2ZR5 A;  2A3E A;  5HT1 A;  4R0X A;  3AS2 A;  3UQB A;  3W4R A;  2LPV A;  1K9T A;  3UF8 A;  2D9F A;  2XP8 A;  1HKI A;  4WJX A;  1ZB5 A;  1GPF A;  1HKM A;  3WD3 A;  1FKL A;  5DIV A;  3G6M A;  1GRJ A;  4W9O A;  4QT2 A;  3IKG A;  3TDB A;  4DRJ A;  4FAP A;  4URI A;  2A3B A;  3B8S A;  1A7X A;  2PN0 A;  2MNT A;  1EIB A;  1H0I A;  3ARS A;  3ARP A;  4JYS A;  1JNT A;  1T11 A;  3KCE A;  4IT4 A;  1W9V A;  2XP6 A;  1ZK6 A;  1KFW A;  4DWS C;  4LGX A;  2AOS A;  2A3A A;  4DRP A;  1ZCN A;  3CHC A;  1Q6I A;  4KQZ A;  3IKD A;  3AS0 A;  3WL1 A;  1OGG A;  3O5O A;  1QPL A;  2ESC A;  4TX0 A;  4U86 A;  4W9Q A;  1RD6 A;  4HBO A;  4TNS A;  1WNO A;  1U79 A;  1PIN A;  1F8A B;  2L2S A;  2YBU A;  3B9A A;  3EIP A;  1FKB A;  2O9O A;  3G6L A;  4TW6 A;  2PV1 A;  2DSV A;  1JNE A;  4WKF A;  2Q5A A;  1ZBW A;  1D7H A;  2F23 A;  2ITK A;  4TW8 A;  3O5L A;  1M5Y A;  1E6N A;  3KAH A;  2KI3 A;  4LAW A;  3KZ7 A;  3QOK A;  3B7X A;  1KT0 A;  1FKS A;  3RGC A;  1W1P A;  1EQ3 A;  4HBE A;  4ZPW R;  4DH0 A;  4ZPT R;  2WLZ A;  4O2T A;  2OLH A;  3TCZ A;  1NH6 A;  4DZ2 A;  4WKA A;  3O5K A;  4U85 A;  2PPO A;  2PPN A;  2QF8 A;  2JZV A;  1BL4 A;  4JFM A;  1FKH A;  3OA5 A;  4S3K A;  1FJD A;  4DRK A;  4MNM A;  3WL0 A;  3WD0 A;  2WK2 A;  1FFQ A;  3EY6 A;  1GUV A;  4Z2K A;  3FXY A;  4S3J A;  3AQU A;  2KFW A;  1HJX A;  3CZ8 A;  4UDM A;  4WKH A;  1NSG A;  3BMB A;  1W1V A;  2RUQ A;  4JFJ A;  2KE0 A;  1LL4 A;  3AS3 A;  1D7J A;  3ARY A;  5DIT A; 
#chains in the Genus database with same CATH homology
 1W26 A;  2KGJ A;  1LG2 A;  4ODN A;  3ODK A;  2ZQV A;  4P8V A;  1FKG A;  1W1Y A;  2DG9 A;  1FKD A;  4NSB A;  4N19 A;  1EYM A;  2RQS A;  1YAT A;  3H9R B;  4P8X A;  3ARZ A;  3O5G A;  4DRQ A;  4Z2L A;  2FKE A;  4XAK A;  1UR9 A;  3OOB A;  2F21 A;  5HUA A;  1FKT A;  2DSW A;  3CHE A;  2ZQS A;  1FKK A;  1SYT A;  2DSU A;  4Q7N A;  1NWR A;  4DRI A;  5HBF A;  2AWG A;  1NWS A;  2ZR6 A;  2B31 A;  4PTM A;  1E6R A;  1UR8 A;  2K8I A;  4Z2H A;  1PBK A;  4WK9 A;  4IQ2 A;  3WKZ A;  4DRH A;  2XPA A;  1ZU8 A;  4IQC A;  4KR0 B;  1R9H A;  4ODM A;  4DZ3 A;  4MTV A;  3VAW A;  2RUR A;  4ZS6 A;  1ZL1 A;  4NZC A;  3TC5 A;  1E6Z A;  1W1T A;  3I6C A;  3O5F A;  3UI6 A;  2UZ5 A;  3RME A;  3ARV A;  3UI4 A;  2DG4 A;  1D7I A;  2OFN A;  1ITX A;  2G41 A;  1D2K A;  1LJY A;  1Q1C A;  4IT6 A;  4L72 B;  2Y78 A;  4MAV A;  3O5J A;  3ARW A;  3O5M A;  3UQI A;  1ZBV A;  3WD1 A;  4MPK A;  1XHG A;  3ARO A;  3NRK A;  1NMW A;  4C02 B;  1TCO C;  2F2D A;  1JNS A;  4G2P A;  1O6I A;  1HKJ A;  2XP4 A;  1ZBK A;  3GPK A;  4AY1 A;  3CGM A;  5D75 A;  3ARU A;  3RFW A;  4IPX A;  3RM9 A;  2DT3 A;  3ART A;  2VN1 A;  3O5R A;  1W9U A;  2FDM A;  3KAI A;  1FKR A;  1B6C A;  4ODR A;  1NMV A;  1ROU A;  1SR0 A;  3FAP A;  4ODO A;  4QZV B;  4ODK A;  4JFK A;  3O5Q A;  4DT4 A;  3PRA A;  4MNJ A;  4FN2 A;  3KAC A;  5JH8 A;  4JFL A;  3B9D A;  5HW7 A;  1E9L A;  3PA7 A;  1E15 A;  1W9P A;  2ZQU A;  3O5D A;  2KR7 A;  3WD4 A;  2ZQT A;  5HWB A;  1Q6H A;  5GPG A;  5HW8 A;  1D6O A;  4MGV A;  1LL7 A;  3KAG A;  4QT3 A;  2O92 A;  1EHN A;  3NI6 A;  3WQW A;  4Z2I A;  1KT1 A;  5J6E A;  3CH9 A;  5GPR A;  2M1I A;  2LKN A;  3O5E A;  3RM8 A;  2LGO A;  2A3C A;  3CGN A;  4LAX A;  2FAP A;  1GOI A;  3ARR A;  1E6P A;  1J6Y A;  3WIJ A;  1QPF A;  2PV2 A;  2DG3 A;  2MF9 A;  1H0G A;  4JFI A;  1OWQ A;  1ROT A;  2RUD A;  1Y0O A;  4Q22 A;  3ALG A;  4P8U A;  2PI6 A;  2MLZ A;  1FFR A;  4BF8 A;  4Z2G A;  1C9H A;  2PPP A;  2XP3 A;  3KAD A;  4U84 A;  1J4R A;  4DWS A;  2IUZ A;  3KAB A;  5HTG A;  4W9P A;  3O5P A;  4MNL A;  3UI5 A;  2RSE A;  2DT1 A;  1YW5 A;  3MDY B;  4DRN A;  2DT0 A;  1FKI A;  1BKF A;  5DO2 A;  1VF8 A;  4MNK A;  2WLY A;  4ODQ A;  1XRV A;  4LAY A;  2MLX A;  1HKK A;  3ARX A;  4TYO A;  2VCD A;  2XP5 A;  2XPB A;  3CHF A;  1P5Q A;  1WB0 A;  4QIB A;  4DWS D;  1JVW A;  3WH0 A;  5HWC A;  3JYJ A;  2XP7 A;  4R5E A;  1CTN A;  2M08 A;  1LG1 A;  3PRD A;  4DRM A;  1FKF A;  4DIP A;  1NWT A;  3O5I A;  3FY1 A;  4HAR A;  1FD9 A;  2WM0 A;  3PR9 A;  2YBT A;  1OGB A;  3BXW A;  4DRO A;  1HJV A;  4LAV A;  4ITZ A;  3PRB A;  1HXV A;  3ALF A;  3LUO A;  4ML4 A;  1IX5 A;  3KAF A;  5DF0 A;  1N1A A;  2MPH A;  5B8I C;  3WD2 A;  2KO7 A;  2ZR4 A;  1HJW A;  4MSP A;  3JYM A;  2LJ4 A;  4GIV A;  2DPE A;  4WIW A;  3IK8 A;  4ODP A;  3AS1 A;  3ARQ A;  1L1P A;  1QZ2 A;  3NTP A;  4P8W A;  1LQ0 A;  1Q6U A;  2PBC A;  5GQB A;  1X6L A;  5DIU A;  3UQA A;  1EDQ A;  2G8Z A;  2N87 A;  4NNR A;  2IF4 A;  1NWU A;  1LL6 A;  2PV3 A;  2F4E A;  1FAP A;  3CHD A;  3B9E A;  3IHZ A;  4GGQ A;  5DEZ A;  2DSZ A;  4ODL A;  2XP9 A;  2MLY A;  5BXJ A;  1FKJ A;  5I98 A;  4L3N A;  4ZPV R;  4J4N A;  2M2A A;  1TFV A;  1J4H A;  5HKG A;  1WAW A;  1X6N A;  2RUC A;  3JXV A;  2DT2 A;  1J4I A;  4G50 A;  1F40 A;  4Z2J A;  3RM4 A;  4DWS B;  5HW6 A;  1JND A;  4W5U A;  1ZBC A;  3WQV A;  4J4O A;  4TW7 A;  2ZR5 A;  2A3E A;  5HT1 A;  4R0X A;  3AS2 A;  3UQB A;  3W4R A;  2LPV A;  1K9T A;  3UF8 A;  2D9F A;  2XP8 A;  1HKI A;  4WJX A;  1ZB5 A;  1GPF A;  1HKM A;  3WD3 A;  1FKL A;  5DIV A;  3G6M A;  4W9O A;  4QT2 A;  3IKG A;  3TDB A;  4DRJ A;  4FAP A;  4URI A;  2A3B A;  3B8S A;  1A7X A;  2MNT A;  1EIB A;  1H0I A;  3ARS A;  3ARP A;  4JYS A;  1JNT A;  1T11 A;  3KCE A;  4IT4 A;  1W9V A;  2XP6 A;  1ZK6 A;  1KFW A;  4DWS C;  4LGX A;  2AOS A;  2A3A A;  4DRP A;  1ZCN A;  3CHC A;  1Q6I A;  4KQZ A;  3IKD A;  3AS0 A;  3WL1 A;  1OGG A;  3O5O A;  1QPL A;  2ESC A;  4TX0 A;  4U86 A;  4W9Q A;  1RD6 A;  4HBO A;  4TNS A;  1WNO A;  1U79 A;  1PIN A;  1F8A B;  2L2S A;  2YBU A;  3B9A A;  1FKB A;  2O9O A;  3G6L A;  4TW6 A;  2PV1 A;  2DSV A;  1JNE A;  4WKF A;  2Q5A A;  1ZBW A;  1D7H A;  2ITK A;  4TW8 A;  3O5L A;  1M5Y A;  1E6N A;  3KAH A;  2KI3 A;  4LAW A;  3KZ7 A;  3QOK A;  3B7X A;  1KT0 A;  1FKS A;  3RGC A;  1W1P A;  1EQ3 A;  4HBE A;  4ZPW R;  4DH0 A;  4ZPT R;  2WLZ A;  4O2T A;  2OLH A;  3TCZ A;  1NH6 A;  4DZ2 A;  4WKA A;  3O5K A;  4U85 A;  2PPO A;  2PPN A;  2QF8 A;  2JZV A;  1BL4 A;  4JFM A;  1FKH A;  3OA5 A;  4S3K A;  1FJD A;  4DRK A;  4MNM A;  3WL0 A;  3WD0 A;  2WK2 A;  1FFQ A;  3EY6 A;  1GUV A;  4Z2K A;  3FXY A;  4S3J A;  3AQU A;  2KFW A;  1HJX A;  3CZ8 A;  4WKH A;  1NSG A;  1W1V A;  2RUQ A;  4JFJ A;  2KE0 A;  1LL4 A;  3AS3 A;  1D7J A;  3ARY A;  5DIT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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