3IKGA

Structure-based design of novel pin1 inhibitors (i)
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
113
structure length
113
Chain Sequence
EPARVRCSHLLVKHSQSRRPSSWRQEQITRTQEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based design of novel human Pin1 inhibitors (I).
pubmed doi rcsb
molecule tags Isomerase
source organism Homo sapiens
molecule keywords Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
total genus 41
structure length 113
sequence length 113
chains with identical sequence B
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2009-08-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00639 Rotamase PPIC-type PPIASE domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.50.40 Alpha Beta Roll Chitinase A; domain 3 Chitinase A; domain 3 3ikgA00
1YW5A 1QPFA 3JYMA 4GIVA 5HUAA 1JNSA 4DRQA 1A7XA 2LKNA 4R0XA 4W9OA 3IHZA 4DRNA 3IKGA 4MGVA 4QT3A 2ZR4A 4GGQA 1FKGA 1Y0OA 2MPHA 5HTGA 2MLYA 3KAGA 2PPPA 1KT0A 4ODLA 4LAWA 3UI4A 1N1AA 3KABA 4TW6A 1J4HA 3NRKA 1BL4A 1Q1CA 3OOBA 4MSPA 2LGOA 1D7HA 1NMWA 2KFWA 2M1IA 2LJ4A 3PRBA 1YATA 4J4OA 1R9HA 2DG4A 1FAPA 2DG9A 2PBCA 2XPBA 4TNSA 1J6YA 1L1PA 2ZR6A 2KE0A 4ODKA 5DITA 2PPOA 1B6CA 2D9FA 2OFNA 2XP4A 1D6OA 3O5JA 5DIVA 1FKHA 1J4RA 2L2SA 2FKEA 1FJDA 4LAXA 3UI6A 1FD9A 3O5OA 3RFWA 1J4IA 2XP3A 4FN2A 3TC5A 3UQIA 3CGMA 3UQBA 2ZQVA 2RUDA 4JFJA 4TYOA 4JYSA 5HW6A 2XP9A 4BF8A 1FKFA 3CGNA 5DIUA 2F2DA 1C9HA 1FKSA 5HW8A 4TX0A 2ZQTA 5HWBA 3UF8A 4LAYA 3MDYB 1M5YA 2KR7A 2XP8A 2PV2A 4IQCA 1QPLA 3KACA 2XP6A 2M08A 1F8AB 1PBKA 2KI3A 4DRKA 2F21A 4U85A 4IPXA 4ODPA 4C02B 3O5QA 4DH0A 5HT1A 1JVWA 4JFLA 3TDBA 1FKRA 3KAHA 5BXJA 3KAIA 3FAPA 4ODRA 5HKGA 1FKJA 4NNRA 1QZ2A 4IQ2A 3RGCA 3NTPA 3O5KA 3KADA 2RQSA 3KZ7A 2XP5A 3VAWA 4FAPA 4DRPA 4JFIA 1NMVA 2KO7A 4DIPA 2M2AA 3JXVA 3PA7A 4DT4A 5I98A 2RSEA 1FKKA 1EYMA 2RURA 4ODQA 2VCDA 4U84A 2FAPA 2ZQUA 3JYJA 1JNTA 1Q6UA 2MLXA 2PPNA 3O5RA 3O5IA 1FKLA 1P5QA 3IKDA 4DZ2A 2KGJA 2MLZA 4N19A 4DRIA 3PRDA 4LAVA 2ITKA 3GPKA 2UZ5A 4TW7A 1EQ3A 1F40A 2N87A 2JZVA 2XPAA 1Q6HA 1ZK6A 3O5DA 3ODKA 3WH0A 1ROTA 1BKFA 1Q6IA 1T11A 1W26A 5GPGA 3O5FA 5B8IC 3O5LA 2RUCA 4ODNA 5HW7A 3B7XA 4U86A 5HWCA 2MNTA 4G2PA 1D7JA 4W9PA 2PV1A 4J4NA 1FKBA 1D7IA 2F4EA 3O5GA 2PV3A 4ITZA 1FKTA 3LUOA 3I6CA 3O5PA 4JFMA 1PINA 2ZR5A 4TW8A 4DZ3A 1TCOC 3H9RB 3KAFA 2DG3A 2LPVA 1ZCNA 4JFKA 4W9QA 4QT2A 4DRHA 1FKDA 2MF9A 3IK8A 3O5EA 3UI5A 2IF4A 4ODMA 1KT1A 1NSGA 2RUQA 3O5MA 3TCZA 3UQAA 2VN1A 2Q5AA 1HXVA 3EY6A 4ODOA 2AWGA 4O2TA 1FKIA 4DRMA 1ROUA 1U79A 2ZQSA 5D75A 2XP7A 4G50A 3NI6A 4QIBA 4DRJA 5J6EA 4DROA 2Y78A 3KCEA 2K8IA
chains in the Genus database with same CATH superfamily
5HUAA 5GQBA 1LL7A 4R0XA 1E6ZA 3IHZA 4DRNA 4P8WA 3ALGA 2MLYA 1X6LA 3UI4A 4IT6A 4QZVB 1N1AA 4TW6A 4TW8A 1Q1CA 1HKIA 1D7HA 1D2KA 2DG9A 1NWTA 2XPBA 2ZR6A 3WD1A 2PPOA 3AS1A 2L2SA 1ZBWA 2B31A 1EHNA 3O5OA 1J4IA 3TC5A 4ZPVR 3UQIA 2QF8A 4KQZA 4MPKA 4Z2KA 4WK9A 1JNDA 5HW6A 3WIJA 3ARVA 4BF8A 1FKFA 3ARWA 3WD0A 5HW8A 1FKSA 2A3EA 4NSBA 1K9TA 3CHCA 4LAYA 3KACA 3RM4A 3CHDA 4HARA 2F21A 4U85A 1HJWA 3GTYX 4C02B 3FAPA 5HKGA 1FKJA 3WQWA 3KADA 4DRPA 1NMVA 2M2AA 3PA7A 2RURA 4P8XA 1XHGA 1W1YA 2AOSA 3G6LA 2KGJA 3PR9A 4N19A 3PRDA 4Z2JA 2WLYA 2O92A 3FY1A 2JZVA 1Q6HA 1ZK6A 4L72B 4URIA 3ARTA 1BKFA 3ARZA 1Q6IA 2DT0A 3FXYA 3B7XA 3RM8A 5HW7A 1ZL1A 4U86A 2MNTA 2G41A 1FKBA 1HKJA 1FKTA 3O5PA 3WL0A 1TCOC 3H9RB 4DWSC 1ZB5A 4QT2A 4W9QA 4DRHA 2A3CA 2MF9A 2IF4A 1EIBA 2RUQA 3UQAA 1HXVA 4ODOA 1X6NA 1FKIA 3WQVA 1NWSA 3NI6A 4QIBA 4DRJA 5J6EA 1LL4A 1JNSA 4DRQA 4W9OA 4MGVA 2ZR4A 2MPHA 4AY1A 1TFVA 4LAWA 1ITXA 4Q7NA 1J4HA 3NRKA 1BL4A 4MSPA 2LGOA 2M1IA 3CH9A 3PRBA 1J6YA 1H0IA 5HBFA 2KE0A 4ODKA 4UDMA 3PRAA 4MNKA 4R5EA 2XP4A 1D6OA 1J4RA 3UI6A 1FD9A 2XP3A 3CGMA 4TYOA 4JFJA 1E6NA 3B9EA 2XP9A 3CGNA 1C9HA 4ZS6A 2PV2A 3ARSA 1QPLA 2XP6A 1F8AB 4IPXA 4DH0A 1XRVA 2DSUA 4LGXA 3AROA 3CHFA 3KZ7A 2RSEA 1GPFA 3ALFA 3ARXA 4ZPWR 2FAPA 1JNTA 1Q6UA 3O5RA 3O5IA 1FKLA 2ITKA 2UZ5A 4TW7A 1EQ3A 3WD4A 3ODKA 3WH0A 1ROTA 4MAVA 4W5UA 1ZBCA 4P8UA 5GPGA 1ZBKA 3O5LA 5HWCA 1HKMA 4G2PA 1ZU8A 1KFWA 2F4EA 3B9DA 1E15A 1FFRA 1OWQA 1ZCNA 1OGGA 3O5EA 4ODMA 1OGBA 1NSGA 2VN1A 2G8ZA 4DRMA 1ROUA 4S3KA 4G50A 2Y78A 3AS0A 1YW5A 1QPFA 3IKGA 4HBOA 4QT3A 1HKKA 2YBUA 1E6RA 1FKGA 1Y0OA 5HTGA 1O6IA 2PPPA 1KT0A 3AS2A 1NMWA 1E9LA 2KFWA 2LJ4A 3UQBA 1F40A 4J4OA 1R9HA 2DG4A 1FAPA 2PBCA 5DF0A 4ZPTR 1L1PA 2FDMA 1W9VA 2DT1A 3B9AA 3O5JA 2D9FA 1FKHA 2FKEA 2WLZA 1FJDA 1IX5A 2ZQVA 2PN0A 2RUDA 3RMEA 4JYSA 1NWRA 1LQ0A 2F2DA 4Z2GA 1GUVA 2ZQTA 1LJYA 2OLHA 5HWBA 2XP8A 1LG2A 2M08A 1NWUA 1PBKA 4Z2HA 4ODPA 2DSVA 5HT1A 4JFLA 4Q22A 2IUZA 3G6MA 1QZ2A 4IQ2A 3NTPA 4WKAA 2RQSA 3VAWA 4FAPA 1ZBVA 4DT4A 5I98A 4DWSD 1EYMA 2VCDA 3AQUA 2B5UB 3JYJA 2MLXA 2PPNA 4Z2LA 4DZ2A 1P5QA 3IKDA 2MLZA 3GPKA 1SYTA 2N87A 3WKZA 1E44A 1VF8A 2DSWA 1JCHB 4P8VA 1W26A 3CZ8A 5B8IC 3EIPA 4W9PA 4L3NA 4PTMA 4J4NA 1D7IA 2WM0A 3O5GA 3BXWA 3B8SA 2DT3A 1HJXA 1RD6A 3LUOA 3I6CA 1PINA 1W9PA 4KR0B 4DZ3A 3KAFA 1EDQA 2DG3A 4MTVA 4JFKA 4WJXA 1E6PA 1FKDA 2F23A 1H0GA 3IK8A 4WIWA 2O9OA 1GOIA 3TCZA 4IT4A 2Q5AA 2AWGA 3ARRA 4O2TA 1U79A 4WKHA 5D75A 2XP7A 5GPRA 3RM9A 4DROA 3KCEA 2RUCA 2K8IA 4LAVA 4MNMA 1WAWA 3JYMA 4GIVA 4DWSB 1A7XA 1W1TA 2LKNA 3ARUA 1WNOA 4MNJA 2DSZA 4GGQA 3KAGA 4ODLA 1GRJA 1SR0A 3KABA 3OOBA 3BMBA 1YATA 4TNSA 4WKFA 4MNLA 1W9UA 5DITA 1B6CA 4NZCA 2OFNA 5DIVA 3AS3A 2A3BA 5JH8A 3ARQA 4LAXA 3RFWA 4FN2A 2EULA 1HJVA 2ESCA 5DIUA 3GU0A 4XAKA 3WD3A 4TX0A 3UF8A 3MDYB 1M5YA 2DPEA 2KR7A 4IQCA 2YBTA 4DWSA 3W4RA 4Z2IA 2KI3A 4DRKA 3OA5A 3WD2A 5DEZA 2ETNA 3O5QA 1JVWA 3TDBA 1FKRA 3KAHA 5BXJA 3KAIA 4ODRA 4NNRA 5DO2A 3RGCA 3O5KA 2XP5A 3CHEA 2DT2A 4JFIA 2KO7A 4DIPA 3JXVA 1FKKA 4ODQA 1WB0A 1W1PA 4U84A 2ZQUA 4DRIA 1W1VA 2XPAA 3O5DA 3ARYA 2P4VA 1CTNA 1T11A 3O5FA 4S3JA 4ODNA 2A3AA 3ARPA 1D7JA 2PI6A 2PV1A 1LG1A 2PV3A 4ITZA 4JFMA 2ZR5A 1NH6A 1UR9A 1FFQA 2LPVA 4HBEA 1UR8A 4ML4A 3UI5A 1KT1A 3O5MA 3WL1A 3EY6A 1JNEA 2ZQSA 3QOKA 1LL6A 2WK2A
chains in the Genus database with same CATH topology
5HUAA 5GQBA 1LL7A 4R0XA 1E6ZA 3IHZA 4DRNA 4P8WA 3ALGA 2MLYA 1X6LA 3UI4A 4IT6A 4QZVB 1N1AA 4TW6A 4TW8A 1Q1CA 1HKIA 1D7HA 1D2KA 2DG9A 1NWTA 2XPBA 2ZR6A 3WD1A 2PPOA 3AS1A 2L2SA 1ZBWA 2B31A 1EHNA 3O5OA 1J4IA 3TC5A 4ZPVR 3UQIA 2QF8A 4KQZA 4MPKA 4Z2KA 4WK9A 1JNDA 5HW6A 3WIJA 3ARVA 4BF8A 1FKFA 3ARWA 3WD0A 5HW8A 1FKSA 2A3EA 4NSBA 1K9TA 3CHCA 4LAYA 3KACA 3RM4A 3CHDA 4HARA 2F21A 4U85A 1HJWA 4C02B 3FAPA 5HKGA 1FKJA 3WQWA 3KADA 4DRPA 1NMVA 2M2AA 3PA7A 2RURA 4P8XA 1XHGA 1W1YA 2AOSA 3G6LA 2KGJA 3PR9A 4N19A 3PRDA 4Z2JA 2WLYA 2O92A 3FY1A 2JZVA 1Q6HA 1ZK6A 4L72B 4URIA 3ARTA 1BKFA 3ARZA 1Q6IA 2DT0A 3FXYA 3B7XA 3RM8A 5HW7A 1ZL1A 4U86A 2MNTA 2G41A 1FKBA 1HKJA 1FKTA 3O5PA 3WL0A 1TCOC 3H9RB 4DWSC 1ZB5A 4QT2A 4W9QA 4DRHA 2A3CA 2MF9A 2IF4A 1EIBA 2RUQA 3UQAA 1HXVA 4ODOA 1X6NA 1FKIA 3WQVA 1NWSA 3NI6A 4QIBA 4DRJA 5J6EA 1LL4A 1JNSA 4DRQA 4W9OA 4MGVA 2ZR4A 2MPHA 4AY1A 1TFVA 4LAWA 1ITXA 4Q7NA 1J4HA 3NRKA 1BL4A 4MSPA 2LGOA 2M1IA 3CH9A 3PRBA 1J6YA 1H0IA 5HBFA 2KE0A 4ODKA 3PRAA 4MNKA 4R5EA 2XP4A 1D6OA 1J4RA 3UI6A 1FD9A 2XP3A 3CGMA 4TYOA 4JFJA 1E6NA 3B9EA 2XP9A 3CGNA 1C9HA 4ZS6A 2PV2A 3ARSA 1QPLA 2XP6A 1F8AB 4IPXA 4DH0A 1XRVA 2DSUA 4LGXA 3AROA 3CHFA 3KZ7A 2RSEA 1GPFA 3ALFA 3ARXA 4ZPWR 2FAPA 1JNTA 1Q6UA 3O5RA 3O5IA 1FKLA 2ITKA 2UZ5A 4TW7A 1EQ3A 3WD4A 3ODKA 3WH0A 1ROTA 4MAVA 4W5UA 1ZBCA 4P8UA 5GPGA 1ZBKA 3O5LA 5HWCA 1HKMA 4G2PA 1ZU8A 1KFWA 2F4EA 3B9DA 1E15A 1FFRA 1OWQA 1ZCNA 1OGGA 3O5EA 4ODMA 1OGBA 1NSGA 2VN1A 2G8ZA 4DRMA 1ROUA 4S3KA 4G50A 2Y78A 3AS0A 1YW5A 1QPFA 3IKGA 4HBOA 4QT3A 1HKKA 2YBUA 1E6RA 1FKGA 1Y0OA 5HTGA 1O6IA 2PPPA 1KT0A 3AS2A 1NMWA 1E9LA 2KFWA 2LJ4A 3UQBA 1F40A 4J4OA 1R9HA 2DG4A 1FAPA 2PBCA 5DF0A 4ZPTR 1L1PA 2FDMA 1W9VA 2DT1A 3B9AA 3O5JA 2D9FA 1FKHA 2FKEA 2WLZA 1FJDA 1IX5A 2ZQVA 2RUDA 3RMEA 4JYSA 1NWRA 1LQ0A 2F2DA 4Z2GA 1GUVA 2ZQTA 1LJYA 2OLHA 5HWBA 2XP8A 1LG2A 2M08A 1NWUA 1PBKA 4Z2HA 4ODPA 2DSVA 5HT1A 4JFLA 4Q22A 2IUZA 3G6MA 1QZ2A 4IQ2A 3NTPA 4WKAA 2RQSA 3VAWA 4FAPA 1ZBVA 4DT4A 5I98A 4DWSD 1EYMA 2VCDA 3AQUA 3JYJA 2MLXA 2PPNA 4Z2LA 4DZ2A 1P5QA 3IKDA 2MLZA 3GPKA 1SYTA 2N87A 3WKZA 1VF8A 2DSWA 4P8VA 1W26A 3CZ8A 5B8IC 4W9PA 4L3NA 4PTMA 4J4NA 1D7IA 3O5GA 2WM0A 3BXWA 3B8SA 2DT3A 1HJXA 1RD6A 3LUOA 3I6CA 1PINA 1W9PA 4KR0B 4DZ3A 3KAFA 1EDQA 2DG3A 4MTVA 4JFKA 4WJXA 1E6PA 1FKDA 1H0GA 3IK8A 4WIWA 2O9OA 1GOIA 3TCZA 4IT4A 2Q5AA 2AWGA 3ARRA 4O2TA 1U79A 4WKHA 5D75A 2XP7A 5GPRA 3RM9A 4DROA 3KCEA 2RUCA 2K8IA 4LAVA 4MNMA 1WAWA 3JYMA 4GIVA 4DWSB 1A7XA 1W1TA 2LKNA 3ARUA 1WNOA 4MNJA 2DSZA 4GGQA 3KAGA 4ODLA 1SR0A 3KABA 3OOBA 1YATA 4TNSA 4WKFA 4MNLA 1W9UA 5DITA 1B6CA 4NZCA 2OFNA 5DIVA 3AS3A 2A3BA 5JH8A 3ARQA 4LAXA 3RFWA 4FN2A 1HJVA 2ESCA 5DIUA 4XAKA 3WD3A 4TX0A 3UF8A 3MDYB 1M5YA 2DPEA 2KR7A 4IQCA 2YBTA 4DWSA 3W4RA 4Z2IA 2KI3A 4DRKA 3OA5A 3WD2A 5DEZA 3O5QA 1JVWA 3TDBA 1FKRA 3KAHA 5BXJA 3KAIA 4ODRA 4NNRA 5DO2A 3RGCA 3O5KA 2XP5A 3CHEA 2DT2A 4JFIA 2KO7A 4DIPA 3JXVA 1FKKA 4ODQA 1WB0A 1W1PA 4U84A 2ZQUA 4DRIA 1W1VA 2XPAA 3O5DA 3ARYA 1CTNA 1T11A 3O5FA 4S3JA 4ODNA 2A3AA 3ARPA 1D7JA 2PI6A 2PV1A 1LG1A 2PV3A 4ITZA 4JFMA 2ZR5A 1NH6A 1UR9A 1FFQA 2LPVA 4HBEA 1UR8A 4ML4A 3UI5A 1KT1A 3O5MA 3WL1A 3EY6A 1JNEA 2ZQSA 3QOKA 1LL6A 2WK2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YW5 A;  1QPF A;  3JYM A;  4GIV A;  5HUA A;  1JNS A;  4DRQ A;  1A7X A;  2LKN A;  4R0X A;  4W9O A;  3IHZ A;  4DRN A;  3IKG A;  4MGV A;  4QT3 A;  2ZR4 A;  4GGQ A;  1FKG A;  1Y0O A;  2MPH A;  5HTG A;  2MLY A;  3KAG A;  2PPP A;  1KT0 A;  4ODL A;  4LAW A;  3UI4 A;  1N1A A;  3KAB A;  4TW6 A;  1J4H A;  3NRK A;  1BL4 A;  1Q1C A;  3OOB A;  4MSP A;  2LGO A;  1D7H A;  1NMW A;  2KFW A;  2M1I A;  2LJ4 A;  3PRB A;  1YAT A;  4J4O A;  1R9H A;  2DG4 A;  1FAP A;  2DG9 A;  2PBC A;  2XPB A;  4TNS A;  1J6Y A;  1L1P A;  2ZR6 A;  2KE0 A;  4ODK A;  5DIT A;  2PPO A;  1B6C A;  2D9F A;  2OFN A;  2XP4 A;  1D6O A;  3O5J A;  5DIV A;  1FKH A;  1J4R A;  2L2S A;  2FKE A;  1FJD A;  4LAX A;  3UI6 A;  1FD9 A;  3O5O A;  3RFW A;  1J4I A;  2XP3 A;  4FN2 A;  3TC5 A;  3UQI A;  3CGM A;  3UQB A;  2ZQV A;  2RUD A;  4JFJ A;  4TYO A;  4JYS A;  5HW6 A;  2XP9 A;  4BF8 A;  1FKF A;  3CGN A;  5DIU A;  2F2D A;  1C9H A;  1FKS A;  5HW8 A;  4TX0 A;  2ZQT A;  5HWB A;  3UF8 A;  4LAY A;  3MDY B;  1M5Y A;  2KR7 A;  2XP8 A;  2PV2 A;  4IQC A;  1QPL A;  3KAC A;  2XP6 A;  2M08 A;  1F8A B;  1PBK A;  2KI3 A;  4DRK A;  2F21 A;  4U85 A;  4IPX A;  4ODP A;  4C02 B;  3O5Q A;  4DH0 A;  5HT1 A;  1JVW A;  4JFL A;  3TDB A;  1FKR A;  3KAH A;  5BXJ A;  3KAI A;  3FAP A;  4ODR A;  5HKG A;  1FKJ A;  4NNR A;  1QZ2 A;  4IQ2 A;  3RGC A;  3NTP A;  3O5K A;  3KAD A;  2RQS A;  3KZ7 A;  2XP5 A;  3VAW A;  4FAP A;  4DRP A;  4JFI A;  1NMV A;  2KO7 A;  4DIP A;  2M2A A;  3JXV A;  3PA7 A;  4DT4 A;  5I98 A;  2RSE A;  1FKK A;  1EYM A;  2RUR A;  4ODQ A;  2VCD A;  4U84 A;  2FAP A;  2ZQU A;  3JYJ A;  1JNT A;  1Q6U A;  2MLX A;  2PPN A;  3O5R A;  3O5I A;  1FKL A;  1P5Q A;  3IKD A;  4DZ2 A;  2KGJ A;  2MLZ A;  4N19 A;  4DRI A;  3PRD A;  4LAV A;  2ITK A;  3GPK A;  2UZ5 A;  4TW7 A;  1EQ3 A;  1F40 A;  2N87 A;  2JZV A;  2XPA A;  1Q6H A;  1ZK6 A;  3O5D A;  3ODK A;  3WH0 A;  1ROT A;  1BKF A;  1Q6I A;  1T11 A;  1W26 A;  5GPG A;  3O5F A;  5B8I C;  3O5L A;  2RUC A;  4ODN A;  5HW7 A;  3B7X A;  4U86 A;  5HWC A;  2MNT A;  4G2P A;  1D7J A;  4W9P A;  2PV1 A;  4J4N A;  1FKB A;  1D7I A;  2F4E A;  3O5G A;  2PV3 A;  4ITZ A;  1FKT A;  3LUO A;  3I6C A;  3O5P A;  4JFM A;  1PIN A;  2ZR5 A;  4TW8 A;  4DZ3 A;  1TCO C;  3H9R B;  3KAF A;  2DG3 A;  2LPV A;  1ZCN A;  4JFK A;  4W9Q A;  4QT2 A;  4DRH A;  1FKD A;  2MF9 A;  3IK8 A;  3O5E A;  3UI5 A;  2IF4 A;  4ODM A;  1KT1 A;  1NSG A;  2RUQ A;  3O5M A;  3TCZ A;  3UQA A;  2VN1 A;  2Q5A A;  1HXV A;  3EY6 A;  4ODO A;  2AWG A;  4O2T A;  1FKI A;  4DRM A;  1ROU A;  1U79 A;  2ZQS A;  5D75 A;  2XP7 A;  4G50 A;  3NI6 A;  4QIB A;  4DRJ A;  5J6E A;  4DRO A;  2Y78 A;  3KCE A;  2K8I A; 
#chains in the Genus database with same CATH topology
 5HUA A;  5GQB A;  1LL7 A;  4R0X A;  1E6Z A;  3IHZ A;  4DRN A;  4P8W A;  3ALG A;  2MLY A;  1X6L A;  3UI4 A;  4IT6 A;  4QZV B;  1N1A A;  4TW6 A;  4TW8 A;  1Q1C A;  1HKI A;  1D7H A;  1D2K A;  2DG9 A;  1NWT A;  2XPB A;  2ZR6 A;  3WD1 A;  2PPO A;  3AS1 A;  2L2S A;  1ZBW A;  2B31 A;  1EHN A;  3O5O A;  1J4I A;  3TC5 A;  4ZPV R;  3UQI A;  2QF8 A;  4KQZ A;  4MPK A;  4Z2K A;  4WK9 A;  1JND A;  5HW6 A;  3WIJ A;  3ARV A;  4BF8 A;  1FKF A;  3ARW A;  3WD0 A;  5HW8 A;  1FKS A;  2A3E A;  4NSB A;  1K9T A;  3CHC A;  4LAY A;  3KAC A;  3RM4 A;  3CHD A;  4HAR A;  2F21 A;  4U85 A;  1HJW A;  3GTY X;  4C02 B;  3FAP A;  5HKG A;  1FKJ A;  3WQW A;  3KAD A;  4DRP A;  1NMV A;  2M2A A;  3PA7 A;  2RUR A;  4P8X A;  1XHG A;  1W1Y A;  2AOS A;  3G6L A;  2KGJ A;  3PR9 A;  4N19 A;  3PRD A;  4Z2J A;  2WLY A;  2O92 A;  3FY1 A;  2JZV A;  1Q6H A;  1ZK6 A;  4L72 B;  4URI A;  3ART A;  1BKF A;  3ARZ A;  1Q6I A;  2DT0 A;  3FXY A;  3B7X A;  3RM8 A;  5HW7 A;  1ZL1 A;  4U86 A;  2MNT A;  2G41 A;  1FKB A;  1HKJ A;  1FKT A;  3O5P A;  3WL0 A;  1TCO C;  3H9R B;  4DWS C;  1ZB5 A;  4QT2 A;  4W9Q A;  4DRH A;  2A3C A;  2MF9 A;  2IF4 A;  1EIB A;  2RUQ A;  3UQA A;  1HXV A;  4ODO A;  1X6N A;  1FKI A;  3WQV A;  1NWS A;  3NI6 A;  4QIB A;  4DRJ A;  5J6E A;  1LL4 A;  1JNS A;  4DRQ A;  4W9O A;  4MGV A;  2ZR4 A;  2MPH A;  4AY1 A;  1TFV A;  4LAW A;  1ITX A;  4Q7N A;  1J4H A;  3NRK A;  1BL4 A;  4MSP A;  2LGO A;  2M1I A;  3CH9 A;  3PRB A;  1J6Y A;  1H0I A;  5HBF A;  2KE0 A;  4ODK A;  4UDM A;  3PRA A;  4MNK A;  4R5E A;  2XP4 A;  1D6O A;  1J4R A;  3UI6 A;  1FD9 A;  2XP3 A;  3CGM A;  4TYO A;  4JFJ A;  1E6N A;  3B9E A;  2XP9 A;  3CGN A;  1C9H A;  4ZS6 A;  2PV2 A;  3ARS A;  1QPL A;  2XP6 A;  1F8A B;  4IPX A;  4DH0 A;  1XRV A;  2DSU A;  4LGX A;  3ARO A;  3CHF A;  3KZ7 A;  2RSE A;  1GPF A;  3ALF A;  3ARX A;  4ZPW R;  2FAP A;  1JNT A;  1Q6U A;  3O5R A;  3O5I A;  1FKL A;  2ITK A;  2UZ5 A;  4TW7 A;  1EQ3 A;  3WD4 A;  3ODK A;  3WH0 A;  1ROT A;  4MAV A;  4W5U A;  1ZBC A;  4P8U A;  5GPG A;  1ZBK A;  3O5L A;  5HWC A;  1HKM A;  4G2P A;  1ZU8 A;  1KFW A;  2F4E A;  3B9D A;  1E15 A;  1FFR A;  1OWQ A;  1ZCN A;  1OGG A;  3O5E A;  4ODM A;  1OGB A;  1NSG A;  2VN1 A;  2G8Z A;  4DRM A;  1ROU A;  4S3K A;  4G50 A;  2Y78 A;  3AS0 A;  1YW5 A;  1QPF A;  3IKG A;  4HBO A;  4QT3 A;  1HKK A;  2YBU A;  1E6R A;  1FKG A;  1Y0O A;  5HTG A;  1O6I A;  2PPP A;  1KT0 A;  3AS2 A;  1NMW A;  1E9L A;  2KFW A;  2LJ4 A;  3UQB A;  1F40 A;  4J4O A;  1R9H A;  2DG4 A;  1FAP A;  2PBC A;  5DF0 A;  4ZPT R;  1L1P A;  2FDM A;  1W9V A;  2DT1 A;  3B9A A;  3O5J A;  2D9F A;  1FKH A;  2FKE A;  2WLZ A;  1FJD A;  1IX5 A;  2ZQV A;  2PN0 A;  2RUD A;  3RME A;  4JYS A;  1NWR A;  1LQ0 A;  2F2D A;  4Z2G A;  1GUV A;  2ZQT A;  1LJY A;  2OLH A;  5HWB A;  2XP8 A;  1LG2 A;  2M08 A;  1NWU A;  1PBK A;  4Z2H A;  4ODP A;  2DSV A;  5HT1 A;  4JFL A;  4Q22 A;  2IUZ A;  3G6M A;  1QZ2 A;  4IQ2 A;  3NTP A;  4WKA A;  2RQS A;  3VAW A;  4FAP A;  1ZBV A;  4DT4 A;  5I98 A;  4DWS D;  1EYM A;  2VCD A;  3AQU A;  2B5U B;  3JYJ A;  2MLX A;  2PPN A;  4Z2L A;  4DZ2 A;  1P5Q A;  3IKD A;  2MLZ A;  3GPK A;  1SYT A;  2N87 A;  3WKZ A;  1E44 A;  1VF8 A;  2DSW A;  1JCH B;  4P8V A;  1W26 A;  3CZ8 A;  5B8I C;  3EIP A;  4W9P A;  4L3N A;  4PTM A;  4J4N A;  1D7I A;  2WM0 A;  3O5G A;  3BXW A;  3B8S A;  2DT3 A;  1HJX A;  1RD6 A;  3LUO A;  3I6C A;  1PIN A;  1W9P A;  4KR0 B;  4DZ3 A;  3KAF A;  1EDQ A;  2DG3 A;  4MTV A;  4JFK A;  4WJX A;  1E6P A;  1FKD A;  2F23 A;  1H0G A;  3IK8 A;  4WIW A;  2O9O A;  1GOI A;  3TCZ A;  4IT4 A;  2Q5A A;  2AWG A;  3ARR A;  4O2T A;  1U79 A;  4WKH A;  5D75 A;  2XP7 A;  5GPR A;  3RM9 A;  4DRO A;  3KCE A;  2RUC A;  2K8I A;  4LAV A;  4MNM A;  1WAW A;  3JYM A;  4GIV A;  4DWS B;  1A7X A;  1W1T A;  2LKN A;  3ARU A;  1WNO A;  4MNJ A;  2DSZ A;  4GGQ A;  3KAG A;  4ODL A;  1GRJ A;  1SR0 A;  3KAB A;  3OOB A;  3BMB A;  1YAT A;  4TNS A;  4WKF A;  4MNL A;  1W9U A;  5DIT A;  1B6C A;  4NZC A;  2OFN A;  5DIV A;  3AS3 A;  2A3B A;  5JH8 A;  3ARQ A;  4LAX A;  3RFW A;  4FN2 A;  2EUL A;  1HJV A;  2ESC A;  5DIU A;  3GU0 A;  4XAK A;  3WD3 A;  4TX0 A;  3UF8 A;  3MDY B;  1M5Y A;  2DPE A;  2KR7 A;  4IQC A;  2YBT A;  4DWS A;  3W4R A;  4Z2I A;  2KI3 A;  4DRK A;  3OA5 A;  3WD2 A;  5DEZ A;  2ETN A;  3O5Q A;  1JVW A;  3TDB A;  1FKR A;  3KAH A;  5BXJ A;  3KAI A;  4ODR A;  4NNR A;  5DO2 A;  3RGC A;  3O5K A;  2XP5 A;  3CHE A;  2DT2 A;  4JFI A;  2KO7 A;  4DIP A;  3JXV A;  1FKK A;  4ODQ A;  1WB0 A;  1W1P A;  4U84 A;  2ZQU A;  4DRI A;  1W1V A;  2XPA A;  3O5D A;  3ARY A;  2P4V A;  1CTN A;  1T11 A;  3O5F A;  4S3J A;  4ODN A;  2A3A A;  3ARP A;  1D7J A;  2PI6 A;  2PV1 A;  1LG1 A;  2PV3 A;  4ITZ A;  4JFM A;  2ZR5 A;  1NH6 A;  1UR9 A;  1FFQ A;  2LPV A;  4HBE A;  1UR8 A;  4ML4 A;  3UI5 A;  1KT1 A;  3O5M A;  3WL1 A;  3EY6 A;  1JNE A;  2ZQS A;  3QOK A;  1LL6 A;  2WK2 A; 
#chains in the Genus database with same CATH homology
 5HUA A;  5GQB A;  1LL7 A;  4R0X A;  1E6Z A;  3IHZ A;  4DRN A;  4P8W A;  3ALG A;  2MLY A;  1X6L A;  3UI4 A;  4IT6 A;  4QZV B;  1N1A A;  4TW6 A;  4TW8 A;  1Q1C A;  1HKI A;  1D7H A;  1D2K A;  2DG9 A;  1NWT A;  2XPB A;  2ZR6 A;  3WD1 A;  2PPO A;  3AS1 A;  2L2S A;  1ZBW A;  2B31 A;  1EHN A;  3O5O A;  1J4I A;  3TC5 A;  4ZPV R;  3UQI A;  2QF8 A;  4KQZ A;  4MPK A;  4Z2K A;  4WK9 A;  1JND A;  5HW6 A;  3WIJ A;  3ARV A;  4BF8 A;  1FKF A;  3ARW A;  3WD0 A;  5HW8 A;  1FKS A;  2A3E A;  4NSB A;  1K9T A;  3CHC A;  4LAY A;  3KAC A;  3RM4 A;  3CHD A;  4HAR A;  2F21 A;  4U85 A;  1HJW A;  4C02 B;  3FAP A;  5HKG A;  1FKJ A;  3WQW A;  3KAD A;  4DRP A;  1NMV A;  2M2A A;  3PA7 A;  2RUR A;  4P8X A;  1XHG A;  1W1Y A;  2AOS A;  3G6L A;  2KGJ A;  3PR9 A;  4N19 A;  3PRD A;  4Z2J A;  2WLY A;  2O92 A;  3FY1 A;  2JZV A;  1Q6H A;  1ZK6 A;  4L72 B;  4URI A;  3ART A;  1BKF A;  3ARZ A;  1Q6I A;  2DT0 A;  3FXY A;  3B7X A;  3RM8 A;  5HW7 A;  1ZL1 A;  4U86 A;  2MNT A;  2G41 A;  1FKB A;  1HKJ A;  1FKT A;  3O5P A;  3WL0 A;  1TCO C;  3H9R B;  4DWS C;  1ZB5 A;  4QT2 A;  4W9Q A;  4DRH A;  2A3C A;  2MF9 A;  2IF4 A;  1EIB A;  2RUQ A;  3UQA A;  1HXV A;  4ODO A;  1X6N A;  1FKI A;  3WQV A;  1NWS A;  3NI6 A;  4QIB A;  4DRJ A;  5J6E A;  1LL4 A;  1JNS A;  4DRQ A;  4W9O A;  4MGV A;  2ZR4 A;  2MPH A;  4AY1 A;  1TFV A;  4LAW A;  1ITX A;  4Q7N A;  1J4H A;  3NRK A;  1BL4 A;  4MSP A;  2LGO A;  2M1I A;  3CH9 A;  3PRB A;  1J6Y A;  1H0I A;  5HBF A;  2KE0 A;  4ODK A;  3PRA A;  4MNK A;  4R5E A;  2XP4 A;  1D6O A;  1J4R A;  3UI6 A;  1FD9 A;  2XP3 A;  3CGM A;  4TYO A;  4JFJ A;  1E6N A;  3B9E A;  2XP9 A;  3CGN A;  1C9H A;  4ZS6 A;  2PV2 A;  3ARS A;  1QPL A;  2XP6 A;  1F8A B;  4IPX A;  4DH0 A;  1XRV A;  2DSU A;  4LGX A;  3ARO A;  3CHF A;  3KZ7 A;  2RSE A;  1GPF A;  3ALF A;  3ARX A;  4ZPW R;  2FAP A;  1JNT A;  1Q6U A;  3O5R A;  3O5I A;  1FKL A;  2ITK A;  2UZ5 A;  4TW7 A;  1EQ3 A;  3WD4 A;  3ODK A;  3WH0 A;  1ROT A;  4MAV A;  4W5U A;  1ZBC A;  4P8U A;  5GPG A;  1ZBK A;  3O5L A;  5HWC A;  1HKM A;  4G2P A;  1ZU8 A;  1KFW A;  2F4E A;  3B9D A;  1E15 A;  1FFR A;  1OWQ A;  1ZCN A;  1OGG A;  3O5E A;  4ODM A;  1OGB A;  1NSG A;  2VN1 A;  2G8Z A;  4DRM A;  1ROU A;  4S3K A;  4G50 A;  2Y78 A;  3AS0 A;  1YW5 A;  1QPF A;  3IKG A;  4HBO A;  4QT3 A;  1HKK A;  2YBU A;  1E6R A;  1FKG A;  1Y0O A;  5HTG A;  1O6I A;  2PPP A;  1KT0 A;  3AS2 A;  1NMW A;  1E9L A;  2KFW A;  2LJ4 A;  3UQB A;  1F40 A;  4J4O A;  1R9H A;  2DG4 A;  1FAP A;  2PBC A;  5DF0 A;  4ZPT R;  1L1P A;  2FDM A;  1W9V A;  2DT1 A;  3B9A A;  3O5J A;  2D9F A;  1FKH A;  2FKE A;  2WLZ A;  1FJD A;  1IX5 A;  2ZQV A;  2RUD A;  3RME A;  4JYS A;  1NWR A;  1LQ0 A;  2F2D A;  4Z2G A;  1GUV A;  2ZQT A;  1LJY A;  2OLH A;  5HWB A;  2XP8 A;  1LG2 A;  2M08 A;  1NWU A;  1PBK A;  4Z2H A;  4ODP A;  2DSV A;  5HT1 A;  4JFL A;  4Q22 A;  2IUZ A;  3G6M A;  1QZ2 A;  4IQ2 A;  3NTP A;  4WKA A;  2RQS A;  3VAW A;  4FAP A;  1ZBV A;  4DT4 A;  5I98 A;  4DWS D;  1EYM A;  2VCD A;  3AQU A;  3JYJ A;  2MLX A;  2PPN A;  4Z2L A;  4DZ2 A;  1P5Q A;  3IKD A;  2MLZ A;  3GPK A;  1SYT A;  2N87 A;  3WKZ A;  1VF8 A;  2DSW A;  4P8V A;  1W26 A;  3CZ8 A;  5B8I C;  4W9P A;  4L3N A;  4PTM A;  4J4N A;  1D7I A;  3O5G A;  2WM0 A;  3BXW A;  3B8S A;  2DT3 A;  1HJX A;  1RD6 A;  3LUO A;  3I6C A;  1PIN A;  1W9P A;  4KR0 B;  4DZ3 A;  3KAF A;  1EDQ A;  2DG3 A;  4MTV A;  4JFK A;  4WJX A;  1E6P A;  1FKD A;  1H0G A;  3IK8 A;  4WIW A;  2O9O A;  1GOI A;  3TCZ A;  4IT4 A;  2Q5A A;  2AWG A;  3ARR A;  4O2T A;  1U79 A;  4WKH A;  5D75 A;  2XP7 A;  5GPR A;  3RM9 A;  4DRO A;  3KCE A;  2RUC A;  2K8I A;  4LAV A;  4MNM A;  1WAW A;  3JYM A;  4GIV A;  4DWS B;  1A7X A;  1W1T A;  2LKN A;  3ARU A;  1WNO A;  4MNJ A;  2DSZ A;  4GGQ A;  3KAG A;  4ODL A;  1SR0 A;  3KAB A;  3OOB A;  1YAT A;  4TNS A;  4WKF A;  4MNL A;  1W9U A;  5DIT A;  1B6C A;  4NZC A;  2OFN A;  5DIV A;  3AS3 A;  2A3B A;  5JH8 A;  3ARQ A;  4LAX A;  3RFW A;  4FN2 A;  1HJV A;  2ESC A;  5DIU A;  4XAK A;  3WD3 A;  4TX0 A;  3UF8 A;  3MDY B;  1M5Y A;  2DPE A;  2KR7 A;  4IQC A;  2YBT A;  4DWS A;  3W4R A;  4Z2I A;  2KI3 A;  4DRK A;  3OA5 A;  3WD2 A;  5DEZ A;  3O5Q A;  1JVW A;  3TDB A;  1FKR A;  3KAH A;  5BXJ A;  3KAI A;  4ODR A;  4NNR A;  5DO2 A;  3RGC A;  3O5K A;  2XP5 A;  3CHE A;  2DT2 A;  4JFI A;  2KO7 A;  4DIP A;  3JXV A;  1FKK A;  4ODQ A;  1WB0 A;  1W1P A;  4U84 A;  2ZQU A;  4DRI A;  1W1V A;  2XPA A;  3O5D A;  3ARY A;  1CTN A;  1T11 A;  3O5F A;  4S3J A;  4ODN A;  2A3A A;  3ARP A;  1D7J A;  2PI6 A;  2PV1 A;  1LG1 A;  2PV3 A;  4ITZ A;  4JFM A;  2ZR5 A;  1NH6 A;  1UR9 A;  1FFQ A;  2LPV A;  4HBE A;  1UR8 A;  4ML4 A;  3UI5 A;  1KT1 A;  3O5M A;  3WL1 A;  3EY6 A;  1JNE A;  2ZQS A;  3QOK A;  1LL6 A;  2WK2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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