4DRMA

Evaluation of synthetic fk506 analogs as ligands for fkbp51 and fkbp52: complex of fkbp51 with {3-[(1r)-3-(3,4-dimethoxyphenyl)-1-({[(2s)-1-{[(1s,2r)-2-ethyl-1-hydroxycyclohexyl](oxo)acetyl}piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
128
structure length
128
Chain Sequence
GAPATVTEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52.
pubmed doi rcsb
molecule tags Isomerase
source organism Homo sapiens
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP5
total genus 34
structure length 128
sequence length 128
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2012-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00254 FKBP_C FKBP-type peptidyl-prolyl cis-trans isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.50.40 Alpha Beta Roll Chitinase A; domain 3 Chitinase A; domain 3 4drmA00
4W9PA 2F2DA 2ITKA 2JZVA 5HW8A 2D9FA 2KO7A 3KAGA 2XP5A 3LUOA 1PINA 2PPOA 4JFMA 4DRKA 1R9HA 1W26A 3NI6A 1Q6IA 4TNSA 4NNRA 2LPVA 5DIUA 3GPKA 4C02B 1FJDA 4DROA 1JNTA 1D7JA 1QZ2A 4DIPA 4DH0A 1BL4A 5HTGA 2MNTA 4GGQA 4W9QA 5HW7A 1NSGA 2ZR6A 3O5PA 5HKGA 2RQSA 2DG3A 3IKGA 4DT4A 2XPAA 2ZR4A 1N1AA 1F40A 3JYMA 4U84A 2RUCA 3H9RB 2Y78A 1J4RA 1Q6UA 3I6CA 3KAIA 5HUAA 1EQ3A 1T11A 4LAXA 5B8IC 2ZQSA 3UI4A 2PV1A 3O5OA 2RUQA 1FKRA 5DITA 1FKSA 4FAPA 2PBCA 3KADA 4IQCA 4W9OA 4JYSA 4TX0A 4DRJA 4DRMA 5I98A 2FAPA 4TW8A 4DRIA 2F4EA 4MGVA 1Q6HA 1FKIA 2DG4A 2FKEA 2ZQTA 4LAWA 3IHZA 2AWGA 2XP9A 3ODKA 2M2AA 1NMWA 3O5JA 2MLZA 4IPXA 3RGCA 3UI5A 1J4IA 1U79A 4ODPA 1L1PA 2M1IA 1M5YA 2MPHA 2KR7A 4JFJA 2OFNA 4ODLA 1D7HA 3IKDA 3UF8A 3KZ7A 4ITZA 3WH0A 1BKFA 1FKBA 2XP7A 3EY6A 4JFIA 2IF4A 4QT3A 4U86A 2KE0A 4R0XA 2KFWA 3KACA 1ZK6A 3CGMA 4ODNA 1P5QA 1YATA 2MLYA 4J4NA 2MF9A 4ODQA 3UI6A 1ROTA 2M08A 2ZR5A 4G2PA 3O5QA 1J6YA 5HW6A 1A7XA 2KI3A 1KT1A 2VCDA 1FKFA 3KABA 2PV3A 4JFLA 4LAYA 4ODOA 2UZ5A 1EYMA 3FAPA 3UQAA 4DRQA 3O5EA 1KT0A 3UQIA 2RSEA 4ODMA 2LJ4A 3JYJA 5HT1A 3O5DA 4G50A 3PRDA 5DIVA 4QT2A 1TCOC 4DZ3A 4ODRA 1J4HA 2LGOA 3JXVA 4GIVA 2VN1A 1YW5A 1ZCNA 1QPLA 2PPNA 2RUDA 3KAHA 1ROUA 3O5MA 5GPGA 1F8AB 3O5RA 4JFKA 3O5KA 2N87A 2DG9A 1FKTA 3OOBA 1QPFA 2XP4A 4U85A 2PV2A 4DRNA 4DRPA 2K8IA 4J4OA 5J6EA 3UQBA 2L2SA 1Q1CA 4TW6A 4N19A 2PPPA 4O2TA 4MSPA 1PBKA 2XP3A 2XP8A 1FKKA 3TDBA 4IQ2A 1HXVA 1NMVA 4DRHA 3TCZA 1D6OA 2XP6A 2XPBA 1FAPA 3O5FA 3NRKA 1JVWA 3O5LA 3RFWA 2LKNA 1C9HA 1FKDA 5HWCA 3VAWA 5D75A 1D7IA 2ZQUA 3PRBA 2F21A 2ZQVA 3O5GA 3KAFA 5HWBA 2KGJA 1FKHA 1FKLA 3IK8A 3NTPA 3CGNA 1FKJA 1Y0OA 4DZ2A 1JNSA 5BXJA 1FKGA 3PA7A 1FD9A 4FN2A 4ODKA 3MDYB 3TC5A 4BF8A 2RURA 4LAVA 4TW7A 3O5IA 1B6CA 2MLXA 3KCEA 3B7XA 4QIBA 2Q5AA 4TYOA
chains in the Genus database with same CATH superfamily
1W1TA 2DT1A 2KO7A 2XP5A 1ZBCA 4JFMA 1W1PA 1R9HA 3NI6A 4P8UA 5GQBA 4DROA 1JNTA 1D7JA 4DIPA 3ARUA 3ARQA 1NSGA 2ZR6A 3O5PA 5JH8A 2RQSA 1E15A 3AS1A 3ARTA 3H9RB 1J4RA 1Q6UA 1GRJA 1EQ3A 4HARA 5DITA 4FAPA 2A3AA 3RM4A 4W9OA 4W5UA 4TX0A 4DRJA 3RM8A 4R5EA 4QZVB 2DT3A 2WLZA 4S3KA 2ZQTA 3QOKA 2XP9A 2M2AA 3UI5A 2M1IA 1D7HA 3KZ7A 2XP7A 4U86A 3WQVA 5DF0A 2MF9A 4MAVA 2M08A 3O5QA 5HW6A 1A7XA 2KI3A 3KABA 4ODOA 2PV3A 2A3BA 4DRQA 4Z2LA 1TCOC 3ARVA 4S3JA 4GIVA 2VN1A 3KAHA 1ROUA 1XRVA 4JFKA 4NZCA 3OOBA 4U85A 4DRNA 4DRPA 2K8IA 4TW6A 4MSPA 3TDBA 1D6OA 1FAPA 3OA5A 3NRKA 1KFWA 1FKDA 5HBFA 3AQUA 2F21A 3O5GA 3CGNA 3CHDA 4MPKA 5BXJA 2AOSA 4Z2KA 3CZ8A 1E6NA 4FN2A 4BF8A 4Z2GA 1UR9A 3ARPA 3B7XA 2EULA 4J4NA 4W9PA 2F2DA 2ITKA 2JZVA 5HW8A 2D9FA 4Q7NA 1ITXA 1PINA 1W26A 1Q6IA 4TNSA 1ZB5A 2DSWA 4ZPVR 1BL4A 2MNTA 4GGQA 4W9QA 5HW7A 2DSVA 4DWSC 1VF8A 4ZPTR 2DG3A 1FFRA 3CHEA 4XAKA 1N1AA 1F40A 1HJVA 2RUCA 3WQWA 1T11A 4LAXA 3AS3A 1FKRA 3KADA 4IQCA 4JYSA 2DSZA 4DRMA 4WIWA 2FAPA 4TW8A 4DRIA 4MNLA 2DG4A 4LAWA 3W4RA 2AWGA 2MLZA 3RGCA 1U79A 2OFNA 1ZL1A 1BKFA 1FKBA 2O9OA 2KFWA 3CGMA 1P5QA 1YATA 1EIBA 4G2PA 4LAYA 3UQAA 2RSEA 4P8XA 4ODMA 1IX5A 3O5DA 5DIVA 1GOIA 4DZ3A 1J4HA 4WK9A 1YW5A 1ZCNA 1H0IA 2B5UB 1F8AB 3O5RA 4IT6A 2N87A 2DSUA 1QPFA 3ARXA 2PV2A 4J4OA 4MNMA 4Q22A 3UQBA 4N19A 4O2TA 1PBKA 1FKKA 2P4VA 1HXVA 3O5LA 4DWSD 1C9HA 1JNEA 5HWCA 4MNKA 4KQZA 3AROA 3PRBA 5HWBA 2ZQVA 1NWUA 3NTPA 3WD2A 1Y0OA 2DT0A 4URIA 1LL6A 4IT4A 3TC5A 2RURA 4LAVA 1ZBVA 4Z2HA 4WKHA 4KR0B 2YBUA 4QIBA 1XHGA 3KAGA 4MTVA 3LUOA 1OWQA 2PPOA 1D2KA 4NNRA 5DIUA 1O6IA 3GPKA 1OGGA 3ALFA 2OLHA 4ZPWR 3G6MA 1X6NA 4NSBA 1NH6A 4DT4A 2XPAA 4U84A 4P8WA 1X6LA 2Y78A 3I6CA 3KAIA 4ML4A 3WD3A 5B8IC 2ZQSA 3UI4A 2PV1A 1E6RA 4Z2JA 1SYTA 4Z2IA 3FXYA 1CTNA 4MGVA 1LQ0A 1Q6HA 3CH9A 3WD4A 3ODKA 3RMEA 3O5JA 3WD1A 1J4IA 4ODPA 1HKJA 1M5YA 2MPHA 2KR7A 4JFJA 4ODLA 3IKDA 3UF8A 2G41A 4ITZA 3EY6A 4JFIA 2IF4A 4QT3A 2KE0A 4LGXA 4WKAA 1W1YA 3KACA 1ZK6A 2B31A 4WKFA 2MLYA 1NWRA 3B8SA 4ODQA 1ROTA 3GTYX 2ZR5A 3WKZA 1J6YA 1GUVA 1KT1A 1FKFA 1W9VA 3ALGA 2A3CA 3FAPA 3AS0A 2LJ4A 1W9UA 1RD6A 2WLYA 3B9DA 4QT2A 1HKIA 2LGOA 3JXVA 4L3NA 3RM9A 1JCHB 1QPLA 2RUDA 3O5MA 5GPGA 3O5KA 2DG9A 4DWSA 2L2SA 1LG2A 4ZS6A 2XP8A 5GPRA 1WB0A 1UR8A 3B9AA 2XPBA 1JVWA 2LKNA 1WNOA 3CHFA 3KAFA 1EHNA 1HJWA 1HKKA 1FKHA 3ARSA 3GU0A 1LJYA 3WD0A 1FKJA 4DZ2A 1FKGA 3PA7A 1W9PA 2YBTA 3BXWA 3ARWA 3MDYB 4TW7A 2G8ZA 1EDQA 2MLXA 3KCEA 4PTMA 2Q5AA 4TYOA 5DO2A 2ESCA 2PN0A 4DRKA 1FJDA 4C02B 2LPVA 1LG1A 1WAWA 2IUZA 4DWSB 1QZ2A 4DH0A 5HTGA 4UDMA 3BMBA 1HKMA 5DEZA 3WIJA 5HKGA 4P8VA 3IKGA 2ZR4A 3ARZA 3JYMA 3G6LA 1LL4A 5HUAA 3O5OA 2RUQA 3PRAA 4HBOA 4AY1A 3ARRA 1FKSA 1E6ZA 4WJXA 2PBCA 5I98A 2F4EA 1FKIA 3AS2A 3CHCA 3ARYA 1H0GA 2FKEA 3IHZA 4IPXA 1NMWA 1NWSA 1L1PA 2DT2A 3WH0A 4R0XA 2ETNA 4ODNA 1ZBWA 1TFVA 3UI6A 3B9EA 2DPEA 4JFLA 2VCDA 5J6EA 2PI6A 2UZ5A 1EYMA 3O5EA 1KT0A 3UQIA 2WM0A 3WL1A 3JYJA 4L72B 5HT1A 4G50A 3WL0A 3PRDA 2QF8A 1E9LA 1ZU8A 4ODRA 1ZBKA 2PPNA 2A3EA 1K9TA 1JNDA 2O92A 1FKTA 2XP4A 1SR0A 4HBEA 1W1VA 1OGBA 1Q1CA 2PPPA 2XP3A 3PR9A 4IQ2A 1E6PA 1NMVA 3FY1A 3TCZA 2XP6A 4DRHA 1GPFA 3RFWA 3VAWA 5D75A 1D7IA 2ZQUA 1NWTA 2KGJA 1FKLA 3IK8A 2F23A 1HJXA 1LL7A 2FDMA 1JNSA 3EIPA 1E44A 1FFQA 1FD9A 4ODKA 4MNJA 2WK2A 3O5IA 1B6CA 3O5FA
chains in the Genus database with same CATH topology
1W1TA 2DT1A 2KO7A 2XP5A 1ZBCA 4JFMA 1W1PA 1R9HA 3NI6A 4P8UA 5GQBA 4DROA 1JNTA 1D7JA 4DIPA 3ARUA 3ARQA 1NSGA 2ZR6A 3O5PA 5JH8A 2RQSA 1E15A 3AS1A 3ARTA 3H9RB 1J4RA 1Q6UA 1EQ3A 4HARA 5DITA 4FAPA 2A3AA 3RM4A 4W9OA 4W5UA 4TX0A 4DRJA 3RM8A 4R5EA 4QZVB 2DT3A 2WLZA 4S3KA 2ZQTA 3QOKA 2XP9A 2M2AA 3UI5A 2M1IA 1D7HA 3KZ7A 2XP7A 4U86A 3WQVA 5DF0A 2MF9A 4MAVA 2M08A 3O5QA 5HW6A 1A7XA 2KI3A 3KABA 4ODOA 2PV3A 2A3BA 4DRQA 4Z2LA 1TCOC 3ARVA 4S3JA 4GIVA 2VN1A 3KAHA 1ROUA 1XRVA 4JFKA 4NZCA 3OOBA 4U85A 4DRNA 4DRPA 2K8IA 4TW6A 4MSPA 3TDBA 1D6OA 1FAPA 3OA5A 3NRKA 1KFWA 1FKDA 5HBFA 3AQUA 2F21A 3O5GA 3CGNA 3CHDA 4MPKA 5BXJA 2AOSA 4Z2KA 3CZ8A 1E6NA 4FN2A 4BF8A 4Z2GA 1UR9A 3ARPA 3B7XA 4J4NA 4W9PA 2F2DA 2ITKA 2JZVA 5HW8A 2D9FA 4Q7NA 1ITXA 1PINA 1W26A 1Q6IA 4TNSA 1ZB5A 2DSWA 4ZPVR 1BL4A 2MNTA 4GGQA 4W9QA 5HW7A 2DSVA 4DWSC 1VF8A 4ZPTR 2DG3A 1FFRA 3CHEA 4XAKA 1N1AA 1F40A 1HJVA 2RUCA 3WQWA 1T11A 4LAXA 3AS3A 1FKRA 3KADA 4IQCA 4JYSA 2DSZA 4DRMA 4WIWA 2FAPA 4TW8A 4DRIA 4MNLA 2DG4A 4LAWA 3W4RA 2AWGA 2MLZA 3RGCA 1U79A 2OFNA 1ZL1A 1BKFA 1FKBA 2O9OA 2KFWA 3CGMA 1P5QA 1YATA 1EIBA 4G2PA 4LAYA 3UQAA 2RSEA 4P8XA 4ODMA 1IX5A 3O5DA 5DIVA 1GOIA 4DZ3A 1J4HA 4WK9A 1YW5A 1ZCNA 1H0IA 1F8AB 3O5RA 4IT6A 2N87A 2DSUA 1QPFA 3ARXA 2PV2A 4J4OA 4MNMA 4Q22A 3UQBA 4N19A 4O2TA 1PBKA 1FKKA 1HXVA 3O5LA 4DWSD 1C9HA 1JNEA 5HWCA 4MNKA 4KQZA 3AROA 3PRBA 5HWBA 2ZQVA 1NWUA 3NTPA 3WD2A 1Y0OA 2DT0A 4URIA 1LL6A 4IT4A 3TC5A 2RURA 4LAVA 1ZBVA 4Z2HA 4WKHA 4KR0B 2YBUA 4QIBA 1XHGA 3KAGA 4MTVA 3LUOA 1OWQA 2PPOA 1D2KA 4NNRA 5DIUA 1O6IA 3GPKA 1OGGA 3ALFA 2OLHA 4ZPWR 3G6MA 1X6NA 4NSBA 1NH6A 4DT4A 2XPAA 4U84A 4P8WA 1X6LA 2Y78A 3I6CA 3KAIA 4ML4A 3WD3A 5B8IC 2ZQSA 3UI4A 2PV1A 1E6RA 4Z2JA 1SYTA 4Z2IA 3FXYA 1CTNA 4MGVA 1LQ0A 1Q6HA 3CH9A 3WD4A 3ODKA 3RMEA 3O5JA 3WD1A 1J4IA 4ODPA 1HKJA 1M5YA 2MPHA 2KR7A 4JFJA 4ODLA 3IKDA 3UF8A 2G41A 4ITZA 3EY6A 4JFIA 2IF4A 4QT3A 2KE0A 4LGXA 4WKAA 1W1YA 3KACA 1ZK6A 2B31A 4WKFA 2MLYA 1NWRA 3B8SA 4ODQA 1ROTA 2ZR5A 3WKZA 1J6YA 1GUVA 1KT1A 1FKFA 1W9VA 3ALGA 2A3CA 3FAPA 3AS0A 2LJ4A 1W9UA 1RD6A 2WLYA 3B9DA 4QT2A 1HKIA 2LGOA 3JXVA 4L3NA 3RM9A 1QPLA 2RUDA 3O5MA 5GPGA 3O5KA 2DG9A 4DWSA 2L2SA 1LG2A 4ZS6A 2XP8A 5GPRA 1WB0A 1UR8A 3B9AA 2XPBA 1JVWA 2LKNA 1WNOA 3CHFA 3KAFA 1EHNA 1HJWA 1HKKA 1FKHA 3ARSA 1LJYA 3WD0A 1FKJA 4DZ2A 1FKGA 3PA7A 1W9PA 2YBTA 3BXWA 3ARWA 3MDYB 4TW7A 2G8ZA 1EDQA 2MLXA 3KCEA 4PTMA 2Q5AA 4TYOA 5DO2A 2ESCA 4DRKA 1FJDA 4C02B 2LPVA 1LG1A 1WAWA 2IUZA 4DWSB 1QZ2A 4DH0A 5HTGA 1HKMA 5DEZA 3WIJA 5HKGA 4P8VA 3IKGA 2ZR4A 3ARZA 3JYMA 3G6LA 1LL4A 5HUAA 3O5OA 2RUQA 3PRAA 4HBOA 4AY1A 3ARRA 1FKSA 1E6ZA 4WJXA 2PBCA 5I98A 2F4EA 1FKIA 3AS2A 3CHCA 3ARYA 1H0GA 2FKEA 3IHZA 4IPXA 1NMWA 1NWSA 1L1PA 2DT2A 3WH0A 4R0XA 4ODNA 1ZBWA 1TFVA 3UI6A 3B9EA 2DPEA 4JFLA 2VCDA 5J6EA 2PI6A 2UZ5A 1EYMA 3O5EA 1KT0A 3UQIA 2WM0A 3WL1A 3JYJA 4L72B 5HT1A 4G50A 3WL0A 3PRDA 2QF8A 1E9LA 1ZU8A 4ODRA 1ZBKA 2PPNA 2A3EA 1K9TA 1JNDA 2O92A 1FKTA 2XP4A 1SR0A 4HBEA 1W1VA 1OGBA 1Q1CA 2PPPA 2XP3A 3PR9A 4IQ2A 1E6PA 1NMVA 3FY1A 3TCZA 2XP6A 4DRHA 1GPFA 3RFWA 3VAWA 5D75A 1D7IA 2ZQUA 1NWTA 2KGJA 1FKLA 3IK8A 1HJXA 1LL7A 2FDMA 1JNSA 1FFQA 1FD9A 4ODKA 4MNJA 2WK2A 3O5IA 1B6CA 3O5FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4W9P A;  2F2D A;  2ITK A;  2JZV A;  5HW8 A;  2D9F A;  2KO7 A;  3KAG A;  2XP5 A;  3LUO A;  1PIN A;  2PPO A;  4JFM A;  4DRK A;  1R9H A;  1W26 A;  3NI6 A;  1Q6I A;  4TNS A;  4NNR A;  2LPV A;  5DIU A;  3GPK A;  4C02 B;  1FJD A;  4DRO A;  1JNT A;  1D7J A;  1QZ2 A;  4DIP A;  4DH0 A;  1BL4 A;  5HTG A;  2MNT A;  4GGQ A;  4W9Q A;  5HW7 A;  1NSG A;  2ZR6 A;  3O5P A;  5HKG A;  2RQS A;  2DG3 A;  3IKG A;  4DT4 A;  2XPA A;  2ZR4 A;  1N1A A;  1F40 A;  3JYM A;  4U84 A;  2RUC A;  3H9R B;  2Y78 A;  1J4R A;  1Q6U A;  3I6C A;  3KAI A;  5HUA A;  1EQ3 A;  1T11 A;  4LAX A;  5B8I C;  2ZQS A;  3UI4 A;  2PV1 A;  3O5O A;  2RUQ A;  1FKR A;  5DIT A;  1FKS A;  4FAP A;  2PBC A;  3KAD A;  4IQC A;  4W9O A;  4JYS A;  4TX0 A;  4DRJ A;  4DRM A;  5I98 A;  2FAP A;  4TW8 A;  4DRI A;  2F4E A;  4MGV A;  1Q6H A;  1FKI A;  2DG4 A;  2FKE A;  2ZQT A;  4LAW A;  3IHZ A;  2AWG A;  2XP9 A;  3ODK A;  2M2A A;  1NMW A;  3O5J A;  2MLZ A;  4IPX A;  3RGC A;  3UI5 A;  1J4I A;  1U79 A;  4ODP A;  1L1P A;  2M1I A;  1M5Y A;  2MPH A;  2KR7 A;  4JFJ A;  2OFN A;  4ODL A;  1D7H A;  3IKD A;  3UF8 A;  3KZ7 A;  4ITZ A;  3WH0 A;  1BKF A;  1FKB A;  2XP7 A;  3EY6 A;  4JFI A;  2IF4 A;  4QT3 A;  4U86 A;  2KE0 A;  4R0X A;  2KFW A;  3KAC A;  1ZK6 A;  3CGM A;  4ODN A;  1P5Q A;  1YAT A;  2MLY A;  4J4N A;  2MF9 A;  4ODQ A;  3UI6 A;  1ROT A;  2M08 A;  2ZR5 A;  4G2P A;  3O5Q A;  1J6Y A;  5HW6 A;  1A7X A;  2KI3 A;  1KT1 A;  2VCD A;  1FKF A;  3KAB A;  2PV3 A;  4JFL A;  4LAY A;  4ODO A;  2UZ5 A;  1EYM A;  3FAP A;  3UQA A;  4DRQ A;  3O5E A;  1KT0 A;  3UQI A;  2RSE A;  4ODM A;  2LJ4 A;  3JYJ A;  5HT1 A;  3O5D A;  4G50 A;  3PRD A;  5DIV A;  4QT2 A;  1TCO C;  4DZ3 A;  4ODR A;  1J4H A;  2LGO A;  3JXV A;  4GIV A;  2VN1 A;  1YW5 A;  1ZCN A;  1QPL A;  2PPN A;  2RUD A;  3KAH A;  1ROU A;  3O5M A;  5GPG A;  1F8A B;  3O5R A;  4JFK A;  3O5K A;  2N87 A;  2DG9 A;  1FKT A;  3OOB A;  1QPF A;  2XP4 A;  4U85 A;  2PV2 A;  4DRN A;  4DRP A;  2K8I A;  4J4O A;  5J6E A;  3UQB A;  2L2S A;  1Q1C A;  4TW6 A;  4N19 A;  2PPP A;  4O2T A;  4MSP A;  1PBK A;  2XP3 A;  2XP8 A;  1FKK A;  3TDB A;  4IQ2 A;  1HXV A;  1NMV A;  4DRH A;  3TCZ A;  1D6O A;  2XP6 A;  2XPB A;  1FAP A;  3O5F A;  3NRK A;  1JVW A;  3O5L A;  3RFW A;  2LKN A;  1C9H A;  1FKD A;  5HWC A;  3VAW A;  5D75 A;  1D7I A;  2ZQU A;  3PRB A;  2F21 A;  2ZQV A;  3O5G A;  3KAF A;  5HWB A;  2KGJ A;  1FKH A;  1FKL A;  3IK8 A;  3NTP A;  3CGN A;  1FKJ A;  1Y0O A;  4DZ2 A;  1JNS A;  5BXJ A;  1FKG A;  3PA7 A;  1FD9 A;  4FN2 A;  4ODK A;  3MDY B;  3TC5 A;  4BF8 A;  2RUR A;  4LAV A;  4TW7 A;  3O5I A;  1B6C A;  2MLX A;  3KCE A;  3B7X A;  4QIB A;  2Q5A A;  4TYO A; 
#chains in the Genus database with same CATH topology
 1W1T A;  2DT1 A;  2KO7 A;  2XP5 A;  1ZBC A;  4JFM A;  1W1P A;  1R9H A;  3NI6 A;  4P8U A;  5GQB A;  4DRO A;  1JNT A;  1D7J A;  4DIP A;  3ARU A;  3ARQ A;  1NSG A;  2ZR6 A;  3O5P A;  5JH8 A;  2RQS A;  1E15 A;  3AS1 A;  3ART A;  3H9R B;  1J4R A;  1Q6U A;  1GRJ A;  1EQ3 A;  4HAR A;  5DIT A;  4FAP A;  2A3A A;  3RM4 A;  4W9O A;  4W5U A;  4TX0 A;  4DRJ A;  3RM8 A;  4R5E A;  4QZV B;  2DT3 A;  2WLZ A;  4S3K A;  2ZQT A;  3QOK A;  2XP9 A;  2M2A A;  3UI5 A;  2M1I A;  1D7H A;  3KZ7 A;  2XP7 A;  4U86 A;  3WQV A;  5DF0 A;  2MF9 A;  4MAV A;  2M08 A;  3O5Q A;  5HW6 A;  1A7X A;  2KI3 A;  3KAB A;  4ODO A;  2PV3 A;  2A3B A;  4DRQ A;  4Z2L A;  1TCO C;  3ARV A;  4S3J A;  4GIV A;  2VN1 A;  3KAH A;  1ROU A;  1XRV A;  4JFK A;  4NZC A;  3OOB A;  4U85 A;  4DRN A;  4DRP A;  2K8I A;  4TW6 A;  4MSP A;  3TDB A;  1D6O A;  1FAP A;  3OA5 A;  3NRK A;  1KFW A;  1FKD A;  5HBF A;  3AQU A;  2F21 A;  3O5G A;  3CGN A;  3CHD A;  4MPK A;  5BXJ A;  2AOS A;  4Z2K A;  3CZ8 A;  1E6N A;  4FN2 A;  4BF8 A;  4Z2G A;  1UR9 A;  3ARP A;  3B7X A;  2EUL A;  4J4N A;  4W9P A;  2F2D A;  2ITK A;  2JZV A;  5HW8 A;  2D9F A;  4Q7N A;  1ITX A;  1PIN A;  1W26 A;  1Q6I A;  4TNS A;  1ZB5 A;  2DSW A;  4ZPV R;  1BL4 A;  2MNT A;  4GGQ A;  4W9Q A;  5HW7 A;  2DSV A;  4DWS C;  1VF8 A;  4ZPT R;  2DG3 A;  1FFR A;  3CHE A;  4XAK A;  1N1A A;  1F40 A;  1HJV A;  2RUC A;  3WQW A;  1T11 A;  4LAX A;  3AS3 A;  1FKR A;  3KAD A;  4IQC A;  4JYS A;  2DSZ A;  4DRM A;  4WIW A;  2FAP A;  4TW8 A;  4DRI A;  4MNL A;  2DG4 A;  4LAW A;  3W4R A;  2AWG A;  2MLZ A;  3RGC A;  1U79 A;  2OFN A;  1ZL1 A;  1BKF A;  1FKB A;  2O9O A;  2KFW A;  3CGM A;  1P5Q A;  1YAT A;  1EIB A;  4G2P A;  4LAY A;  3UQA A;  2RSE A;  4P8X A;  4ODM A;  1IX5 A;  3O5D A;  5DIV A;  1GOI A;  4DZ3 A;  1J4H A;  4WK9 A;  1YW5 A;  1ZCN A;  1H0I A;  2B5U B;  1F8A B;  3O5R A;  4IT6 A;  2N87 A;  2DSU A;  1QPF A;  3ARX A;  2PV2 A;  4J4O A;  4MNM A;  4Q22 A;  3UQB A;  4N19 A;  4O2T A;  1PBK A;  1FKK A;  2P4V A;  1HXV A;  3O5L A;  4DWS D;  1C9H A;  1JNE A;  5HWC A;  4MNK A;  4KQZ A;  3ARO A;  3PRB A;  5HWB A;  2ZQV A;  1NWU A;  3NTP A;  3WD2 A;  1Y0O A;  2DT0 A;  4URI A;  1LL6 A;  4IT4 A;  3TC5 A;  2RUR A;  4LAV A;  1ZBV A;  4Z2H A;  4WKH A;  4KR0 B;  2YBU A;  4QIB A;  1XHG A;  3KAG A;  4MTV A;  3LUO A;  1OWQ A;  2PPO A;  1D2K A;  4NNR A;  5DIU A;  1O6I A;  3GPK A;  1OGG A;  3ALF A;  2OLH A;  4ZPW R;  3G6M A;  1X6N A;  4NSB A;  1NH6 A;  4DT4 A;  2XPA A;  4U84 A;  4P8W A;  1X6L A;  2Y78 A;  3I6C A;  3KAI A;  4ML4 A;  3WD3 A;  5B8I C;  2ZQS A;  3UI4 A;  2PV1 A;  1E6R A;  4Z2J A;  1SYT A;  4Z2I A;  3FXY A;  1CTN A;  4MGV A;  1LQ0 A;  1Q6H A;  3CH9 A;  3WD4 A;  3ODK A;  3RME A;  3O5J A;  3WD1 A;  1J4I A;  4ODP A;  1HKJ A;  1M5Y A;  2MPH A;  2KR7 A;  4JFJ A;  4ODL A;  3IKD A;  3UF8 A;  2G41 A;  4ITZ A;  3EY6 A;  4JFI A;  2IF4 A;  4QT3 A;  2KE0 A;  4LGX A;  4WKA A;  1W1Y A;  3KAC A;  1ZK6 A;  2B31 A;  4WKF A;  2MLY A;  1NWR A;  3B8S A;  4ODQ A;  1ROT A;  3GTY X;  2ZR5 A;  3WKZ A;  1J6Y A;  1GUV A;  1KT1 A;  1FKF A;  1W9V A;  3ALG A;  2A3C A;  3FAP A;  3AS0 A;  2LJ4 A;  1W9U A;  1RD6 A;  2WLY A;  3B9D A;  4QT2 A;  1HKI A;  2LGO A;  3JXV A;  4L3N A;  3RM9 A;  1JCH B;  1QPL A;  2RUD A;  3O5M A;  5GPG A;  3O5K A;  2DG9 A;  4DWS A;  2L2S A;  1LG2 A;  4ZS6 A;  2XP8 A;  5GPR A;  1WB0 A;  1UR8 A;  3B9A A;  2XPB A;  1JVW A;  2LKN A;  1WNO A;  3CHF A;  3KAF A;  1EHN A;  1HJW A;  1HKK A;  1FKH A;  3ARS A;  3GU0 A;  1LJY A;  3WD0 A;  1FKJ A;  4DZ2 A;  1FKG A;  3PA7 A;  1W9P A;  2YBT A;  3BXW A;  3ARW A;  3MDY B;  4TW7 A;  2G8Z A;  1EDQ A;  2MLX A;  3KCE A;  4PTM A;  2Q5A A;  4TYO A;  5DO2 A;  2ESC A;  2PN0 A;  4DRK A;  1FJD A;  4C02 B;  2LPV A;  1LG1 A;  1WAW A;  2IUZ A;  4DWS B;  1QZ2 A;  4DH0 A;  5HTG A;  4UDM A;  3BMB A;  1HKM A;  5DEZ A;  3WIJ A;  5HKG A;  4P8V A;  3IKG A;  2ZR4 A;  3ARZ A;  3JYM A;  3G6L A;  1LL4 A;  5HUA A;  3O5O A;  2RUQ A;  3PRA A;  4HBO A;  4AY1 A;  3ARR A;  1FKS A;  1E6Z A;  4WJX A;  2PBC A;  5I98 A;  2F4E A;  1FKI A;  3AS2 A;  3CHC A;  3ARY A;  1H0G A;  2FKE A;  3IHZ A;  4IPX A;  1NMW A;  1NWS A;  1L1P A;  2DT2 A;  3WH0 A;  4R0X A;  2ETN A;  4ODN A;  1ZBW A;  1TFV A;  3UI6 A;  3B9E A;  2DPE A;  4JFL A;  2VCD A;  5J6E A;  2PI6 A;  2UZ5 A;  1EYM A;  3O5E A;  1KT0 A;  3UQI A;  2WM0 A;  3WL1 A;  3JYJ A;  4L72 B;  5HT1 A;  4G50 A;  3WL0 A;  3PRD A;  2QF8 A;  1E9L A;  1ZU8 A;  4ODR A;  1ZBK A;  2PPN A;  2A3E A;  1K9T A;  1JND A;  2O92 A;  1FKT A;  2XP4 A;  1SR0 A;  4HBE A;  1W1V A;  1OGB A;  1Q1C A;  2PPP A;  2XP3 A;  3PR9 A;  4IQ2 A;  1E6P A;  1NMV A;  3FY1 A;  3TCZ A;  2XP6 A;  4DRH A;  1GPF A;  3RFW A;  3VAW A;  5D75 A;  1D7I A;  2ZQU A;  1NWT A;  2KGJ A;  1FKL A;  3IK8 A;  2F23 A;  1HJX A;  1LL7 A;  2FDM A;  1JNS A;  3EIP A;  1E44 A;  1FFQ A;  1FD9 A;  4ODK A;  4MNJ A;  2WK2 A;  3O5I A;  1B6C A;  3O5F A; 
#chains in the Genus database with same CATH homology
 1W1T A;  2DT1 A;  2KO7 A;  2XP5 A;  1ZBC A;  4JFM A;  1W1P A;  1R9H A;  3NI6 A;  4P8U A;  5GQB A;  4DRO A;  1JNT A;  1D7J A;  4DIP A;  3ARU A;  3ARQ A;  1NSG A;  2ZR6 A;  3O5P A;  5JH8 A;  2RQS A;  1E15 A;  3AS1 A;  3ART A;  3H9R B;  1J4R A;  1Q6U A;  1EQ3 A;  4HAR A;  5DIT A;  4FAP A;  2A3A A;  3RM4 A;  4W9O A;  4W5U A;  4TX0 A;  4DRJ A;  3RM8 A;  4R5E A;  4QZV B;  2DT3 A;  2WLZ A;  4S3K A;  2ZQT A;  3QOK A;  2XP9 A;  2M2A A;  3UI5 A;  2M1I A;  1D7H A;  3KZ7 A;  2XP7 A;  4U86 A;  3WQV A;  5DF0 A;  2MF9 A;  4MAV A;  2M08 A;  3O5Q A;  5HW6 A;  1A7X A;  2KI3 A;  3KAB A;  4ODO A;  2PV3 A;  2A3B A;  4DRQ A;  4Z2L A;  1TCO C;  3ARV A;  4S3J A;  4GIV A;  2VN1 A;  3KAH A;  1ROU A;  1XRV A;  4JFK A;  4NZC A;  3OOB A;  4U85 A;  4DRN A;  4DRP A;  2K8I A;  4TW6 A;  4MSP A;  3TDB A;  1D6O A;  1FAP A;  3OA5 A;  3NRK A;  1KFW A;  1FKD A;  5HBF A;  3AQU A;  2F21 A;  3O5G A;  3CGN A;  3CHD A;  4MPK A;  5BXJ A;  2AOS A;  4Z2K A;  3CZ8 A;  1E6N A;  4FN2 A;  4BF8 A;  4Z2G A;  1UR9 A;  3ARP A;  3B7X A;  4J4N A;  4W9P A;  2F2D A;  2ITK A;  2JZV A;  5HW8 A;  2D9F A;  4Q7N A;  1ITX A;  1PIN A;  1W26 A;  1Q6I A;  4TNS A;  1ZB5 A;  2DSW A;  4ZPV R;  1BL4 A;  2MNT A;  4GGQ A;  4W9Q A;  5HW7 A;  2DSV A;  4DWS C;  1VF8 A;  4ZPT R;  2DG3 A;  1FFR A;  3CHE A;  4XAK A;  1N1A A;  1F40 A;  1HJV A;  2RUC A;  3WQW A;  1T11 A;  4LAX A;  3AS3 A;  1FKR A;  3KAD A;  4IQC A;  4JYS A;  2DSZ A;  4DRM A;  4WIW A;  2FAP A;  4TW8 A;  4DRI A;  4MNL A;  2DG4 A;  4LAW A;  3W4R A;  2AWG A;  2MLZ A;  3RGC A;  1U79 A;  2OFN A;  1ZL1 A;  1BKF A;  1FKB A;  2O9O A;  2KFW A;  3CGM A;  1P5Q A;  1YAT A;  1EIB A;  4G2P A;  4LAY A;  3UQA A;  2RSE A;  4P8X A;  4ODM A;  1IX5 A;  3O5D A;  5DIV A;  1GOI A;  4DZ3 A;  1J4H A;  4WK9 A;  1YW5 A;  1ZCN A;  1H0I A;  1F8A B;  3O5R A;  4IT6 A;  2N87 A;  2DSU A;  1QPF A;  3ARX A;  2PV2 A;  4J4O A;  4MNM A;  4Q22 A;  3UQB A;  4N19 A;  4O2T A;  1PBK A;  1FKK A;  1HXV A;  3O5L A;  4DWS D;  1C9H A;  1JNE A;  5HWC A;  4MNK A;  4KQZ A;  3ARO A;  3PRB A;  5HWB A;  2ZQV A;  1NWU A;  3NTP A;  3WD2 A;  1Y0O A;  2DT0 A;  4URI A;  1LL6 A;  4IT4 A;  3TC5 A;  2RUR A;  4LAV A;  1ZBV A;  4Z2H A;  4WKH A;  4KR0 B;  2YBU A;  4QIB A;  1XHG A;  3KAG A;  4MTV A;  3LUO A;  1OWQ A;  2PPO A;  1D2K A;  4NNR A;  5DIU A;  1O6I A;  3GPK A;  1OGG A;  3ALF A;  2OLH A;  4ZPW R;  3G6M A;  1X6N A;  4NSB A;  1NH6 A;  4DT4 A;  2XPA A;  4U84 A;  4P8W A;  1X6L A;  2Y78 A;  3I6C A;  3KAI A;  4ML4 A;  3WD3 A;  5B8I C;  2ZQS A;  3UI4 A;  2PV1 A;  1E6R A;  4Z2J A;  1SYT A;  4Z2I A;  3FXY A;  1CTN A;  4MGV A;  1LQ0 A;  1Q6H A;  3CH9 A;  3WD4 A;  3ODK A;  3RME A;  3O5J A;  3WD1 A;  1J4I A;  4ODP A;  1HKJ A;  1M5Y A;  2MPH A;  2KR7 A;  4JFJ A;  4ODL A;  3IKD A;  3UF8 A;  2G41 A;  4ITZ A;  3EY6 A;  4JFI A;  2IF4 A;  4QT3 A;  2KE0 A;  4LGX A;  4WKA A;  1W1Y A;  3KAC A;  1ZK6 A;  2B31 A;  4WKF A;  2MLY A;  1NWR A;  3B8S A;  4ODQ A;  1ROT A;  2ZR5 A;  3WKZ A;  1J6Y A;  1GUV A;  1KT1 A;  1FKF A;  1W9V A;  3ALG A;  2A3C A;  3FAP A;  3AS0 A;  2LJ4 A;  1W9U A;  1RD6 A;  2WLY A;  3B9D A;  4QT2 A;  1HKI A;  2LGO A;  3JXV A;  4L3N A;  3RM9 A;  1QPL A;  2RUD A;  3O5M A;  5GPG A;  3O5K A;  2DG9 A;  4DWS A;  2L2S A;  1LG2 A;  4ZS6 A;  2XP8 A;  5GPR A;  1WB0 A;  1UR8 A;  3B9A A;  2XPB A;  1JVW A;  2LKN A;  1WNO A;  3CHF A;  3KAF A;  1EHN A;  1HJW A;  1HKK A;  1FKH A;  3ARS A;  1LJY A;  3WD0 A;  1FKJ A;  4DZ2 A;  1FKG A;  3PA7 A;  1W9P A;  2YBT A;  3BXW A;  3ARW A;  3MDY B;  4TW7 A;  2G8Z A;  1EDQ A;  2MLX A;  3KCE A;  4PTM A;  2Q5A A;  4TYO A;  5DO2 A;  2ESC A;  4DRK A;  1FJD A;  4C02 B;  2LPV A;  1LG1 A;  1WAW A;  2IUZ A;  4DWS B;  1QZ2 A;  4DH0 A;  5HTG A;  1HKM A;  5DEZ A;  3WIJ A;  5HKG A;  4P8V A;  3IKG A;  2ZR4 A;  3ARZ A;  3JYM A;  3G6L A;  1LL4 A;  5HUA A;  3O5O A;  2RUQ A;  3PRA A;  4HBO A;  4AY1 A;  3ARR A;  1FKS A;  1E6Z A;  4WJX A;  2PBC A;  5I98 A;  2F4E A;  1FKI A;  3AS2 A;  3CHC A;  3ARY A;  1H0G A;  2FKE A;  3IHZ A;  4IPX A;  1NMW A;  1NWS A;  1L1P A;  2DT2 A;  3WH0 A;  4R0X A;  4ODN A;  1ZBW A;  1TFV A;  3UI6 A;  3B9E A;  2DPE A;  4JFL A;  2VCD A;  5J6E A;  2PI6 A;  2UZ5 A;  1EYM A;  3O5E A;  1KT0 A;  3UQI A;  2WM0 A;  3WL1 A;  3JYJ A;  4L72 B;  5HT1 A;  4G50 A;  3WL0 A;  3PRD A;  2QF8 A;  1E9L A;  1ZU8 A;  4ODR A;  1ZBK A;  2PPN A;  2A3E A;  1K9T A;  1JND A;  2O92 A;  1FKT A;  2XP4 A;  1SR0 A;  4HBE A;  1W1V A;  1OGB A;  1Q1C A;  2PPP A;  2XP3 A;  3PR9 A;  4IQ2 A;  1E6P A;  1NMV A;  3FY1 A;  3TCZ A;  2XP6 A;  4DRH A;  1GPF A;  3RFW A;  3VAW A;  5D75 A;  1D7I A;  2ZQU A;  1NWT A;  2KGJ A;  1FKL A;  3IK8 A;  1HJX A;  1LL7 A;  2FDM A;  1JNS A;  1FFQ A;  1FD9 A;  4ODK A;  4MNJ A;  2WK2 A;  3O5I A;  1B6C A;  3O5F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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