4DH0A

X-ray crystal structure of 28-o-methylrapamycin complexed with fkbp12: is the cyclohexyl moiety part of the effector domain of rapamycin?
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
107
structure length
107
Chain Sequence
GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray Crystal Structure of 28-O-Methylrapamycin complexed with FKBP12: Is the Cyclohexyl Moiety Part of the Effector Domain of Rapamycin?
doi rcsb
molecule tags Isomerase/immunosuppressant
source organism Homo sapiens
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP1A
total genus 26
structure length 107
sequence length 107
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2012-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00254 FKBP_C FKBP-type peptidyl-prolyl cis-trans isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.50.40 Alpha Beta Roll Chitinase A; domain 3 Chitinase A; domain 3 4dh0A00
3KAFA 3O5RA 4W9QA 2PPNA 4DRMA 4MGVA 2VN1A 4DT4A 5HKGA 5D75A 4R0XA 4LAVA 2F21A 4DRPA 2XP4A 3TDBA 1NMVA 1FKFA 2PV2A 4J4OA 4GGQA 4FAPA 5GPGA 3JYJA 4O2TA 5DIVA 1BL4A 1FKGA 2LJ4A 2KFWA 4ODOA 3UF8A 2MF9A 3WH0A 2MPHA 2FKEA 1KT1A 4JFMA 4U84A 1JNSA 2PBCA 2F4EA 4IPXA 4TNSA 2XP3A 2LPVA 1FKTA 2MNTA 4TW8A 2M2AA 4TW6A 5HWBA 2RSEA 2JZVA 2AWGA 2PV1A 1D7IA 1F8AB 3O5KA 1J6YA 2XPBA 1N1AA 1M5YA 3PA7A 4FN2A 4ODRA 3O5IA 3O5QA 1QPLA 2UZ5A 2XPAA 3UI5A 2KO7A 3O5GA 3NI6A 4JFJA 1Q1CA 2DG9A 3MDYB 1D7HA 2ITKA 2KGJA 2KE0A 2RQSA 3UI6A 2ZR5A 4DH0A 1FKDA 1R9HA 2KI3A 3CGMA 1HXVA 1D6OA 4JYSA 2MLYA 3UQIA 3EY6A 1C9HA 3RGCA 2XP8A 1FKIA 2M1IA 2ZQUA 3OOBA 3LUOA 4JFLA 2D9FA 2MLXA 2Q5AA 3KADA 2ZR4A 3KACA 4ODLA 4DZ3A 5B8IC 3UQAA 2RURA 3UQBA 1T11A 1JVWA 3PRDA 3O5FA 3KABA 4BF8A 4DRIA 4IQ2A 4N19A 3IK8A 4TW7A 5BXJA 5DIUA 1U79A 1J4HA 3TC5A 1ROUA 1JNTA 4J4NA 5HWCA 2ZQTA 1ZK6A 1FJDA 3B7XA 4QT3A 4W9OA 1PBKA 1YATA 5DITA 3UI4A 1FAPA 1Q6IA 4ODMA 2XP6A 3FAPA 3KAHA 2PPPA 4DIPA 1EQ3A 4LAXA 1NSGA 1QPFA 3CGNA 3O5MA 2MLZA 2PPOA 3KAIA 4ODQA 2XP5A 2ZQSA 1B6CA 2XP9A 3IKDA 1FKJA 4ODKA 2IF4A 1Y0OA 2Y78A 4G50A 5J6EA 1F40A 1D7JA 2XP7A 3I6CA 4QT2A 4U85A 2PV3A 1EYMA 4NNRA 3IKGA 4G2PA 5HW7A 1W26A 2L2SA 3NTPA 5HW8A 2LGOA 4U86A 1NMWA 3RFWA 3JYMA 3KCEA 1J4RA 4MSPA 2LKNA 4JFIA 2FAPA 4W9PA 4ODPA 1Q6UA 1FKKA 1Q6HA 1FKSA 1FKLA 2VCDA 5HUAA 1A7XA 3O5PA 3O5LA 3KAGA 2F2DA 3PRBA 3O5EA 4LAYA 4DRHA 2ZQVA 4DZ2A 1FKRA 3IHZA 3GPKA 5HW6A 1J4IA 1YW5A 2K8IA 3VAWA 4DRKA 2N87A 1L1PA 3O5OA 5I98A 4DRNA 3O5JA 2RUCA 1FD9A 1QZ2A 3H9RB 4TX0A 1FKHA 2M08A 5HT1A 3ODKA 2ZR6A 4DRJA 2KR7A 3O5DA 4C02B 3TCZA 1ROTA 1TCOC 1ZCNA 1PINA 4JFKA 4DRQA 1P5QA 1BKFA 2DG3A 5HTGA 3NRKA 4DROA 4ODNA 4ITZA 4LAWA 2DG4A 2RUDA 4IQCA 3KZ7A 4TYOA 1KT0A 1FKBA 3JXVA 4QIBA 2RUQA 4GIVA 2OFNA
chains in the Genus database with same CATH superfamily
2PPNA 5D75A 4MNKA 4R0XA 4LGXA 1NMVA 1ZBWA 2EULA 3JYJA 1BL4A 4KQZA 3RMEA 3UF8A 3WH0A 2MF9A 1JNSA 1KT1A 4U84A 2F4EA 2A3CA 2AWGA 4MNJA 1OWQA 3PA7A 4FN2A 3O5IA 2UZ5A 2XPAA 2KO7A 4JFJA 1Q1CA 2ITKA 2RQSA 1W9UA 2O9OA 5HBFA 3ALFA 3UQIA 3RGCA 2XP8A 3OOBA 3KADA 2ZR4A 3KACA 4DZ3A 1RD6A 4P8VA 1JVWA 4BF8A 2G8ZA 4TW7A 5DIUA 3TC5A 1HKJA 4J4NA 3ARRA 1ZK6A 5DF0A 4QT3A 5DITA 3UI4A 1Q6IA 2XP6A 1IX5A 4DIPA 3AROA 1EQ3A 4LAXA 3O5MA 4P8UA 1W1YA 2AOSA 1ZU8A 1D7JA 4QT2A 5GPRA 3AS2A 3IKGA 4NNRA 1W26A 1X6NA 1LG2A 1GOIA 4ZPTR 1NH6A 5DEZA 1JNEA 5HUAA 1FKSA 3AS3A 4S3JA 2F2DA 4DZ2A 4DRHA 1WB0A 2ZQVA 3IHZA 5HW6A 1J4IA 2N87A 1LL6A 1L1PA 4DRNA 2RUCA 1FKHA 2M08A 2KR7A 3TCZA 1ZCNA 1ZB5A 4DRQA 3ARUA 2DG3A 3RM9A 5HTGA 2DSZA 2WLYA 4ODNA 3ARPA 4MNMA 2RUDA 3KZ7A 4W9QA 2OFNA 4DRMA 1KFWA 2VN1A 4DT4A 5HKGA 4DRPA 1H0GA 2XP4A 3TDBA 4MPKA 5GPGA 2LJ4A 4ODOA 2KFWA 4Z2JA 3RM8A 3WD1A 3BMBA 4TNSA 2MNTA 4TW8A 4TW6A 2DPEA 4Z2KA 5HWBA 2PV1A 1F8AB 5JH8A 1SYTA 1O6IA 1M5YA 1W1VA 4ODRA 3WKZA 4XAKA 3O5QA 3WD2A 1QPLA 4DWSA 2KGJA 2KE0A 4DH0A 4R5EA 3CGMA 4WKHA 3ARWA 1WAWA 4ZPVR 4DWSD 3ARSA 4NZCA 3LUOA 5B8IC 2MLXA 2RURA 1T11A 2DT1A 3FY1A 1FFRA 1LQ0A 3GTYX 1NWUA 3WL1A 1EIBA 1ROUA 1JNTA 1E6RA 2ZQTA 1FFQA 2IUZA 1PBKA 1YATA 3AS0A 4ODMA 2FDMA 1NSGA 2P4VA 2MLZA 2PPOA 4W5UA 3KAIA 5GQBA 2XP9A 1FKJA 2IF4A 2A3EA 1F40A 4Z2LA 1UR8A 2XP7A 4U85A 2PV3A 4Q7NA 4G2PA 1E6ZA 4U86A 1NMWA 3RFWA 1JCHB 3KCEA 2LKNA 4DWSC 4JFIA 2FAPA 3W4RA 4ODPA 1FKKA 1Q6HA 3EIPA 3O5PA 3CHFA 3O5LA 3ARXA 3KAGA 4LAYA 3O5EA 1E15A 3BXWA 3O5OA 3H9RB 3OA5A 2PI6A 5HT1A 1OGBA 2WM0A 4DRJA 4C02B 3CHCA 3GU0A 1EHNA 1X6LA 4ZPWR 1P5QA 1H0IA 2ETNA 4ITZA 2OLHA 1E9LA 3ARTA 4MTVA 4TYOA 1KT0A 4Z2GA 4URIA 3JXVA 1JNDA 3CHDA 2PV2A 3KAFA 3NTPA 3O5RA 3B8SA 2DSWA 4MGVA 4LAVA 2F21A 3WL0A 1HJVA 3G6LA 4J4OA 1E44A 1GRJA 2FKEA 4WKAA 1D2KA 4IPXA 1W9VA 1CTNA 3PR9A 4WJXA 2JZVA 3WIJA 1HKIA 1D7IA 3AS1A 3O5KA 4UDMA 2PN0A 2XPBA 4HBOA 3WQVA 3NI6A 3MDYB 2WLZA 3FXYA 4L72B 3UI6A 2ZR5A 1FKDA 1R9HA 1HXVA 1HJXA 1NWTA 1D6OA 1ZBKA 3CZ8A 4JFLA 2Q5AA 4ODLA 2ESCA 3WD3A 3PRDA 3ARQA 4IQ2A 1SR0A 3IK8A 5BXJA 4HBEA 1ZBVA 1U79A 4NSBA 3CH9A 5HWCA 3B7XA 3RM4A 4KR0B 1FAPA 3FAPA 3KAHA 4ML4A 1NWSA 1QPFA 3ARVA 4AY1A 1ZBCA 1W1PA 4ODQA 1UR9A 2XP5A 1W1TA 2ZQSA 1B6CA 4PTMA 5J6EA 2O92A 1W9PA 1EYMA 3G6MA 1XRVA 5HW8A 1ZL1A 4P8XA 1J4RA 3B9AA 1E6PA 4W9PA 1Q6UA 1FKLA 3GPKA 4WIWA 1YW5A 2K8IA 3VAWA 4HARA 4L3NA 4DRKA 3WD4A 1ITXA 2A3AA 3O5JA 2B31A 1FD9A 1QZ2A 4TX0A 3WQWA 2YBUA 2G41A 3O5DA 1OGGA 1ROTA 1TCOC 4JFKA 1LL7A 2F23A 1BKFA 1HKKA 4S3KA 4DROA 4LAWA 2DG4A 1GUVA 3CHEA 4QIBA 2RUQA 4GIVA 1FKFA 3ARZA 4GGQA 4FAPA 2DT0A 4O2TA 4IT4A 5DIVA 1FKGA 1LL4A 2MPHA 4WKFA 1VF8A 4MAVA 4JFMA 2PBCA 1XHGA 2XP3A 4IT6A 2LPVA 1TFVA 1FKTA 2M2AA 2DSUA 2RSEA 3B9DA 1J6YA 1N1AA 3UI5A 3O5GA 2DG9A 1D7HA 3ARYA 2KI3A 2DT3A 4JYSA 2MLYA 3EY6A 1C9HA 1FKIA 2M1IA 2ZQUA 2WK2A 2D9FA 2DSVA 3UQAA 3UQBA 3O5FA 3KABA 4DRIA 1EDQA 4N19A 1HKMA 1J4HA 4Z2HA 1FJDA 4W9OA 1NWRA 1WNOA 2PPPA 4QZVB 3CGNA 3PRAA 1LJYA 3IKDA 4ODKA 1Y0OA 2Y78A 4G50A 3I6CA 5HW7A 5DO2A 2DT2A 2L2SA 2B5UB 2LGOA 4DWSB 2A3BA 3JYMA 3B9EA 4MSPA 2VCDA 1A7XA 3WD0A 3AQUA 3PRBA 1GPFA 1FKRA 2YBTA 5I98A 4MNLA 2QF8A 1E6NA 1LG1A 3ODKA 2ZR6A 4WK9A 3QOKA 4Z2IA 1PINA 3ALGA 1HJWA 4P8WA 3NRKA 4ZS6A 4Q22A 4IQCA 1FKBA 1K9TA
chains in the Genus database with same CATH topology
2PPNA 5D75A 4MNKA 4R0XA 4LGXA 1NMVA 1ZBWA 3JYJA 1BL4A 4KQZA 3RMEA 3UF8A 3WH0A 2MF9A 1JNSA 1KT1A 4U84A 2F4EA 2A3CA 2AWGA 4MNJA 1OWQA 3PA7A 4FN2A 3O5IA 2UZ5A 2XPAA 2KO7A 4JFJA 1Q1CA 2ITKA 2RQSA 1W9UA 2O9OA 5HBFA 3ALFA 3UQIA 3RGCA 2XP8A 3OOBA 3KADA 2ZR4A 3KACA 4DZ3A 1RD6A 4P8VA 1JVWA 4BF8A 2G8ZA 4TW7A 5DIUA 3TC5A 1HKJA 4J4NA 3ARRA 1ZK6A 5DF0A 4QT3A 5DITA 3UI4A 1Q6IA 2XP6A 1IX5A 4DIPA 3AROA 1EQ3A 4LAXA 3O5MA 4P8UA 1W1YA 2AOSA 1ZU8A 1D7JA 4QT2A 5GPRA 3AS2A 3IKGA 4NNRA 1W26A 1X6NA 1LG2A 1GOIA 4ZPTR 1NH6A 5DEZA 1JNEA 5HUAA 1FKSA 3AS3A 4S3JA 2F2DA 4DZ2A 4DRHA 1WB0A 2ZQVA 3IHZA 5HW6A 1J4IA 2N87A 1LL6A 1L1PA 4DRNA 2RUCA 1FKHA 2M08A 2KR7A 3TCZA 1ZCNA 1ZB5A 4DRQA 3ARUA 2DG3A 3RM9A 5HTGA 2DSZA 2WLYA 4ODNA 3ARPA 4MNMA 2RUDA 3KZ7A 4W9QA 2OFNA 4DRMA 1KFWA 2VN1A 4DT4A 5HKGA 4DRPA 1H0GA 2XP4A 3TDBA 4MPKA 5GPGA 2LJ4A 4ODOA 2KFWA 4Z2JA 3RM8A 3WD1A 4TNSA 2MNTA 4TW8A 4TW6A 2DPEA 4Z2KA 5HWBA 2PV1A 1F8AB 5JH8A 1SYTA 1O6IA 1M5YA 1W1VA 4ODRA 3WKZA 4XAKA 3O5QA 3WD2A 1QPLA 4DWSA 2KGJA 2KE0A 4DH0A 4R5EA 3CGMA 4WKHA 3ARWA 1WAWA 4ZPVR 4DWSD 3ARSA 4NZCA 3LUOA 5B8IC 2MLXA 2RURA 1T11A 2DT1A 3FY1A 1FFRA 1LQ0A 1NWUA 3WL1A 1EIBA 1ROUA 1JNTA 1E6RA 2ZQTA 1FFQA 2IUZA 1PBKA 1YATA 3AS0A 4ODMA 2FDMA 1NSGA 2MLZA 2PPOA 4W5UA 3KAIA 5GQBA 2XP9A 1FKJA 2IF4A 2A3EA 1F40A 4Z2LA 1UR8A 2XP7A 4U85A 2PV3A 4Q7NA 4G2PA 1E6ZA 4U86A 1NMWA 3RFWA 3KCEA 2LKNA 4DWSC 4JFIA 2FAPA 3W4RA 4ODPA 1FKKA 1Q6HA 3O5PA 3CHFA 3O5LA 3ARXA 3KAGA 4LAYA 3O5EA 1E15A 3BXWA 3O5OA 3H9RB 3OA5A 2PI6A 5HT1A 1OGBA 2WM0A 4DRJA 4C02B 3CHCA 1EHNA 1X6LA 4ZPWR 1P5QA 1H0IA 4ITZA 2OLHA 1E9LA 3ARTA 4MTVA 4TYOA 1KT0A 4Z2GA 4URIA 3JXVA 1JNDA 3CHDA 2PV2A 3KAFA 3O5RA 3NTPA 3B8SA 2DSWA 4MGVA 4LAVA 2F21A 3WL0A 1HJVA 3G6LA 4J4OA 2FKEA 4WKAA 1D2KA 4IPXA 1W9VA 1CTNA 3PR9A 4WJXA 2JZVA 3WIJA 1HKIA 1D7IA 3AS1A 3O5KA 2XPBA 4HBOA 3WQVA 3NI6A 3MDYB 2WLZA 3FXYA 4L72B 3UI6A 2ZR5A 1FKDA 1R9HA 1HXVA 1HJXA 1NWTA 1D6OA 1ZBKA 3CZ8A 4JFLA 2Q5AA 4ODLA 2ESCA 3WD3A 3PRDA 3ARQA 4IQ2A 1SR0A 3IK8A 5BXJA 4HBEA 1ZBVA 1U79A 4NSBA 3CH9A 5HWCA 3B7XA 3RM4A 4KR0B 1FAPA 3FAPA 3KAHA 4ML4A 1NWSA 1QPFA 3ARVA 4AY1A 1ZBCA 1W1PA 4ODQA 1UR9A 2XP5A 1W1TA 2ZQSA 1B6CA 4PTMA 5J6EA 2O92A 1W9PA 1EYMA 3G6MA 1XRVA 5HW8A 1ZL1A 4P8XA 1J4RA 3B9AA 1E6PA 4W9PA 1Q6UA 1FKLA 3GPKA 4WIWA 1YW5A 2K8IA 3VAWA 4HARA 4L3NA 4DRKA 3WD4A 1ITXA 2A3AA 3O5JA 2B31A 1FD9A 1QZ2A 4TX0A 3WQWA 2YBUA 2G41A 3O5DA 1OGGA 1ROTA 1TCOC 4JFKA 1LL7A 1BKFA 1HKKA 4S3KA 4DROA 4LAWA 2DG4A 1GUVA 3CHEA 4QIBA 2RUQA 4GIVA 1FKFA 3ARZA 4GGQA 4FAPA 2DT0A 4O2TA 4IT4A 5DIVA 1FKGA 1LL4A 2MPHA 4WKFA 1VF8A 4MAVA 4JFMA 2PBCA 1XHGA 2XP3A 4IT6A 2LPVA 1TFVA 1FKTA 2M2AA 2DSUA 2RSEA 3B9DA 1J6YA 1N1AA 3UI5A 3O5GA 2DG9A 1D7HA 3ARYA 2KI3A 2DT3A 4JYSA 2MLYA 3EY6A 1C9HA 1FKIA 2M1IA 2ZQUA 2WK2A 2D9FA 2DSVA 3UQAA 3UQBA 3O5FA 3KABA 4DRIA 1EDQA 4N19A 1HKMA 1J4HA 4Z2HA 1FJDA 4W9OA 1NWRA 1WNOA 2PPPA 4QZVB 3CGNA 3PRAA 1LJYA 3IKDA 4ODKA 1Y0OA 2Y78A 4G50A 3I6CA 5HW7A 5DO2A 2DT2A 2L2SA 2LGOA 4DWSB 2A3BA 3JYMA 3B9EA 4MSPA 2VCDA 1A7XA 3WD0A 3AQUA 3PRBA 1GPFA 1FKRA 2YBTA 5I98A 4MNLA 2QF8A 1E6NA 1LG1A 3ODKA 2ZR6A 4WK9A 3QOKA 4Z2IA 1PINA 3ALGA 1HJWA 4P8WA 3NRKA 4ZS6A 4Q22A 4IQCA 1FKBA 1K9TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KAF A;  3O5R A;  4W9Q A;  2PPN A;  4DRM A;  4MGV A;  2VN1 A;  4DT4 A;  5HKG A;  5D75 A;  4R0X A;  4LAV A;  2F21 A;  4DRP A;  2XP4 A;  3TDB A;  1NMV A;  1FKF A;  2PV2 A;  4J4O A;  4GGQ A;  4FAP A;  5GPG A;  3JYJ A;  4O2T A;  5DIV A;  1BL4 A;  1FKG A;  2LJ4 A;  2KFW A;  4ODO A;  3UF8 A;  2MF9 A;  3WH0 A;  2MPH A;  2FKE A;  1KT1 A;  4JFM A;  4U84 A;  1JNS A;  2PBC A;  2F4E A;  4IPX A;  4TNS A;  2XP3 A;  2LPV A;  1FKT A;  2MNT A;  4TW8 A;  2M2A A;  4TW6 A;  5HWB A;  2RSE A;  2JZV A;  2AWG A;  2PV1 A;  1D7I A;  1F8A B;  3O5K A;  1J6Y A;  2XPB A;  1N1A A;  1M5Y A;  3PA7 A;  4FN2 A;  4ODR A;  3O5I A;  3O5Q A;  1QPL A;  2UZ5 A;  2XPA A;  3UI5 A;  2KO7 A;  3O5G A;  3NI6 A;  4JFJ A;  1Q1C A;  2DG9 A;  3MDY B;  1D7H A;  2ITK A;  2KGJ A;  2KE0 A;  2RQS A;  3UI6 A;  2ZR5 A;  4DH0 A;  1FKD A;  1R9H A;  2KI3 A;  3CGM A;  1HXV A;  1D6O A;  4JYS A;  2MLY A;  3UQI A;  3EY6 A;  1C9H A;  3RGC A;  2XP8 A;  1FKI A;  2M1I A;  2ZQU A;  3OOB A;  3LUO A;  4JFL A;  2D9F A;  2MLX A;  2Q5A A;  3KAD A;  2ZR4 A;  3KAC A;  4ODL A;  4DZ3 A;  5B8I C;  3UQA A;  2RUR A;  3UQB A;  1T11 A;  1JVW A;  3PRD A;  3O5F A;  3KAB A;  4BF8 A;  4DRI A;  4IQ2 A;  4N19 A;  3IK8 A;  4TW7 A;  5BXJ A;  5DIU A;  1U79 A;  1J4H A;  3TC5 A;  1ROU A;  1JNT A;  4J4N A;  5HWC A;  2ZQT A;  1ZK6 A;  1FJD A;  3B7X A;  4QT3 A;  4W9O A;  1PBK A;  1YAT A;  5DIT A;  3UI4 A;  1FAP A;  1Q6I A;  4ODM A;  2XP6 A;  3FAP A;  3KAH A;  2PPP A;  4DIP A;  1EQ3 A;  4LAX A;  1NSG A;  1QPF A;  3CGN A;  3O5M A;  2MLZ A;  2PPO A;  3KAI A;  4ODQ A;  2XP5 A;  2ZQS A;  1B6C A;  2XP9 A;  3IKD A;  1FKJ A;  4ODK A;  2IF4 A;  1Y0O A;  2Y78 A;  4G50 A;  5J6E A;  1F40 A;  1D7J A;  2XP7 A;  3I6C A;  4QT2 A;  4U85 A;  2PV3 A;  1EYM A;  4NNR A;  3IKG A;  4G2P A;  5HW7 A;  1W26 A;  2L2S A;  3NTP A;  5HW8 A;  2LGO A;  4U86 A;  1NMW A;  3RFW A;  3JYM A;  3KCE A;  1J4R A;  4MSP A;  2LKN A;  4JFI A;  2FAP A;  4W9P A;  4ODP A;  1Q6U A;  1FKK A;  1Q6H A;  1FKS A;  1FKL A;  2VCD A;  5HUA A;  1A7X A;  3O5P A;  3O5L A;  3KAG A;  2F2D A;  3PRB A;  3O5E A;  4LAY A;  4DRH A;  2ZQV A;  4DZ2 A;  1FKR A;  3IHZ A;  3GPK A;  5HW6 A;  1J4I A;  1YW5 A;  2K8I A;  3VAW A;  4DRK A;  2N87 A;  1L1P A;  3O5O A;  5I98 A;  4DRN A;  3O5J A;  2RUC A;  1FD9 A;  1QZ2 A;  3H9R B;  4TX0 A;  1FKH A;  2M08 A;  5HT1 A;  3ODK A;  2ZR6 A;  4DRJ A;  2KR7 A;  3O5D A;  4C02 B;  3TCZ A;  1ROT A;  1TCO C;  1ZCN A;  1PIN A;  4JFK A;  4DRQ A;  1P5Q A;  1BKF A;  2DG3 A;  5HTG A;  3NRK A;  4DRO A;  4ODN A;  4ITZ A;  4LAW A;  2DG4 A;  2RUD A;  4IQC A;  3KZ7 A;  4TYO A;  1KT0 A;  1FKB A;  3JXV A;  4QIB A;  2RUQ A;  4GIV A;  2OFN A; 
#chains in the Genus database with same CATH topology
 2PPN A;  5D75 A;  4MNK A;  4R0X A;  4LGX A;  1NMV A;  1ZBW A;  2EUL A;  3JYJ A;  1BL4 A;  4KQZ A;  3RME A;  3UF8 A;  3WH0 A;  2MF9 A;  1JNS A;  1KT1 A;  4U84 A;  2F4E A;  2A3C A;  2AWG A;  4MNJ A;  1OWQ A;  3PA7 A;  4FN2 A;  3O5I A;  2UZ5 A;  2XPA A;  2KO7 A;  4JFJ A;  1Q1C A;  2ITK A;  2RQS A;  1W9U A;  2O9O A;  5HBF A;  3ALF A;  3UQI A;  3RGC A;  2XP8 A;  3OOB A;  3KAD A;  2ZR4 A;  3KAC A;  4DZ3 A;  1RD6 A;  4P8V A;  1JVW A;  4BF8 A;  2G8Z A;  4TW7 A;  5DIU A;  3TC5 A;  1HKJ A;  4J4N A;  3ARR A;  1ZK6 A;  5DF0 A;  4QT3 A;  5DIT A;  3UI4 A;  1Q6I A;  2XP6 A;  1IX5 A;  4DIP A;  3ARO A;  1EQ3 A;  4LAX A;  3O5M A;  4P8U A;  1W1Y A;  2AOS A;  1ZU8 A;  1D7J A;  4QT2 A;  5GPR A;  3AS2 A;  3IKG A;  4NNR A;  1W26 A;  1X6N A;  1LG2 A;  1GOI A;  4ZPT R;  1NH6 A;  5DEZ A;  1JNE A;  5HUA A;  1FKS A;  3AS3 A;  4S3J A;  2F2D A;  4DZ2 A;  4DRH A;  1WB0 A;  2ZQV A;  3IHZ A;  5HW6 A;  1J4I A;  2N87 A;  1LL6 A;  1L1P A;  4DRN A;  2RUC A;  1FKH A;  2M08 A;  2KR7 A;  3TCZ A;  1ZCN A;  1ZB5 A;  4DRQ A;  3ARU A;  2DG3 A;  3RM9 A;  5HTG A;  2DSZ A;  2WLY A;  4ODN A;  3ARP A;  4MNM A;  2RUD A;  3KZ7 A;  4W9Q A;  2OFN A;  4DRM A;  1KFW A;  2VN1 A;  4DT4 A;  5HKG A;  4DRP A;  1H0G A;  2XP4 A;  3TDB A;  4MPK A;  5GPG A;  2LJ4 A;  4ODO A;  2KFW A;  4Z2J A;  3RM8 A;  3WD1 A;  3BMB A;  4TNS A;  2MNT A;  4TW8 A;  4TW6 A;  2DPE A;  4Z2K A;  5HWB A;  2PV1 A;  1F8A B;  5JH8 A;  1SYT A;  1O6I A;  1M5Y A;  1W1V A;  4ODR A;  3WKZ A;  4XAK A;  3O5Q A;  3WD2 A;  1QPL A;  4DWS A;  2KGJ A;  2KE0 A;  4DH0 A;  4R5E A;  3CGM A;  4WKH A;  3ARW A;  1WAW A;  4ZPV R;  4DWS D;  3ARS A;  4NZC A;  3LUO A;  5B8I C;  2MLX A;  2RUR A;  1T11 A;  2DT1 A;  3FY1 A;  1FFR A;  1LQ0 A;  3GTY X;  1NWU A;  3WL1 A;  1EIB A;  1ROU A;  1JNT A;  1E6R A;  2ZQT A;  1FFQ A;  2IUZ A;  1PBK A;  1YAT A;  3AS0 A;  4ODM A;  2FDM A;  1NSG A;  2P4V A;  2MLZ A;  2PPO A;  4W5U A;  3KAI A;  5GQB A;  2XP9 A;  1FKJ A;  2IF4 A;  2A3E A;  1F40 A;  4Z2L A;  1UR8 A;  2XP7 A;  4U85 A;  2PV3 A;  4Q7N A;  4G2P A;  1E6Z A;  4U86 A;  1NMW A;  3RFW A;  1JCH B;  3KCE A;  2LKN A;  4DWS C;  4JFI A;  2FAP A;  3W4R A;  4ODP A;  1FKK A;  1Q6H A;  3EIP A;  3O5P A;  3CHF A;  3O5L A;  3ARX A;  3KAG A;  4LAY A;  3O5E A;  1E15 A;  3BXW A;  3O5O A;  3H9R B;  3OA5 A;  2PI6 A;  5HT1 A;  1OGB A;  2WM0 A;  4DRJ A;  4C02 B;  3CHC A;  3GU0 A;  1EHN A;  1X6L A;  4ZPW R;  1P5Q A;  1H0I A;  2ETN A;  4ITZ A;  2OLH A;  1E9L A;  3ART A;  4MTV A;  4TYO A;  1KT0 A;  4Z2G A;  4URI A;  3JXV A;  1JND A;  3CHD A;  2PV2 A;  3KAF A;  3NTP A;  3O5R A;  3B8S A;  2DSW A;  4MGV A;  4LAV A;  2F21 A;  3WL0 A;  1HJV A;  3G6L A;  4J4O A;  1E44 A;  1GRJ A;  2FKE A;  4WKA A;  1D2K A;  4IPX A;  1W9V A;  1CTN A;  3PR9 A;  4WJX A;  2JZV A;  3WIJ A;  1HKI A;  1D7I A;  3AS1 A;  3O5K A;  4UDM A;  2PN0 A;  2XPB A;  4HBO A;  3WQV A;  3NI6 A;  3MDY B;  2WLZ A;  3FXY A;  4L72 B;  3UI6 A;  2ZR5 A;  1FKD A;  1R9H A;  1HXV A;  1HJX A;  1NWT A;  1D6O A;  1ZBK A;  3CZ8 A;  4JFL A;  2Q5A A;  4ODL A;  2ESC A;  3WD3 A;  3PRD A;  3ARQ A;  4IQ2 A;  1SR0 A;  3IK8 A;  5BXJ A;  4HBE A;  1ZBV A;  1U79 A;  4NSB A;  3CH9 A;  5HWC A;  3B7X A;  3RM4 A;  4KR0 B;  1FAP A;  3FAP A;  3KAH A;  4ML4 A;  1NWS A;  1QPF A;  3ARV A;  4AY1 A;  1ZBC A;  1W1P A;  4ODQ A;  1UR9 A;  2XP5 A;  1W1T A;  2ZQS A;  1B6C A;  4PTM A;  5J6E A;  2O92 A;  1W9P A;  1EYM A;  3G6M A;  1XRV A;  5HW8 A;  1ZL1 A;  4P8X A;  1J4R A;  3B9A A;  1E6P A;  4W9P A;  1Q6U A;  1FKL A;  3GPK A;  4WIW A;  1YW5 A;  2K8I A;  3VAW A;  4HAR A;  4L3N A;  4DRK A;  3WD4 A;  1ITX A;  2A3A A;  3O5J A;  2B31 A;  1FD9 A;  1QZ2 A;  4TX0 A;  3WQW A;  2YBU A;  2G41 A;  3O5D A;  1OGG A;  1ROT A;  1TCO C;  4JFK A;  1LL7 A;  2F23 A;  1BKF A;  1HKK A;  4S3K A;  4DRO A;  4LAW A;  2DG4 A;  1GUV A;  3CHE A;  4QIB A;  2RUQ A;  4GIV A;  1FKF A;  3ARZ A;  4GGQ A;  4FAP A;  2DT0 A;  4O2T A;  4IT4 A;  5DIV A;  1FKG A;  1LL4 A;  2MPH A;  4WKF A;  1VF8 A;  4MAV A;  4JFM A;  2PBC A;  1XHG A;  2XP3 A;  4IT6 A;  2LPV A;  1TFV A;  1FKT A;  2M2A A;  2DSU A;  2RSE A;  3B9D A;  1J6Y A;  1N1A A;  3UI5 A;  3O5G A;  2DG9 A;  1D7H A;  3ARY A;  2KI3 A;  2DT3 A;  4JYS A;  2MLY A;  3EY6 A;  1C9H A;  1FKI A;  2M1I A;  2ZQU A;  2WK2 A;  2D9F A;  2DSV A;  3UQA A;  3UQB A;  3O5F A;  3KAB A;  4DRI A;  1EDQ A;  4N19 A;  1HKM A;  1J4H A;  4Z2H A;  1FJD A;  4W9O A;  1NWR A;  1WNO A;  2PPP A;  4QZV B;  3CGN A;  3PRA A;  1LJY A;  3IKD A;  4ODK A;  1Y0O A;  2Y78 A;  4G50 A;  3I6C A;  5HW7 A;  5DO2 A;  2DT2 A;  2L2S A;  2B5U B;  2LGO A;  4DWS B;  2A3B A;  3JYM A;  3B9E A;  4MSP A;  2VCD A;  1A7X A;  3WD0 A;  3AQU A;  3PRB A;  1GPF A;  1FKR A;  2YBT A;  5I98 A;  4MNL A;  2QF8 A;  1E6N A;  1LG1 A;  3ODK A;  2ZR6 A;  4WK9 A;  3QOK A;  4Z2I A;  1PIN A;  3ALG A;  1HJW A;  4P8W A;  3NRK A;  4ZS6 A;  4Q22 A;  4IQC A;  1FKB A;  1K9T A; 
#chains in the Genus database with same CATH homology
 2PPN A;  5D75 A;  4MNK A;  4R0X A;  4LGX A;  1NMV A;  1ZBW A;  3JYJ A;  1BL4 A;  4KQZ A;  3RME A;  3UF8 A;  3WH0 A;  2MF9 A;  1JNS A;  1KT1 A;  4U84 A;  2F4E A;  2A3C A;  2AWG A;  4MNJ A;  1OWQ A;  3PA7 A;  4FN2 A;  3O5I A;  2UZ5 A;  2XPA A;  2KO7 A;  4JFJ A;  1Q1C A;  2ITK A;  2RQS A;  1W9U A;  2O9O A;  5HBF A;  3ALF A;  3UQI A;  3RGC A;  2XP8 A;  3OOB A;  3KAD A;  2ZR4 A;  3KAC A;  4DZ3 A;  1RD6 A;  4P8V A;  1JVW A;  4BF8 A;  2G8Z A;  4TW7 A;  5DIU A;  3TC5 A;  1HKJ A;  4J4N A;  3ARR A;  1ZK6 A;  5DF0 A;  4QT3 A;  5DIT A;  3UI4 A;  1Q6I A;  2XP6 A;  1IX5 A;  4DIP A;  3ARO A;  1EQ3 A;  4LAX A;  3O5M A;  4P8U A;  1W1Y A;  2AOS A;  1ZU8 A;  1D7J A;  4QT2 A;  5GPR A;  3AS2 A;  3IKG A;  4NNR A;  1W26 A;  1X6N A;  1LG2 A;  1GOI A;  4ZPT R;  1NH6 A;  5DEZ A;  1JNE A;  5HUA A;  1FKS A;  3AS3 A;  4S3J A;  2F2D A;  4DZ2 A;  4DRH A;  1WB0 A;  2ZQV A;  3IHZ A;  5HW6 A;  1J4I A;  2N87 A;  1LL6 A;  1L1P A;  4DRN A;  2RUC A;  1FKH A;  2M08 A;  2KR7 A;  3TCZ A;  1ZCN A;  1ZB5 A;  4DRQ A;  3ARU A;  2DG3 A;  3RM9 A;  5HTG A;  2DSZ A;  2WLY A;  4ODN A;  3ARP A;  4MNM A;  2RUD A;  3KZ7 A;  4W9Q A;  2OFN A;  4DRM A;  1KFW A;  2VN1 A;  4DT4 A;  5HKG A;  4DRP A;  1H0G A;  2XP4 A;  3TDB A;  4MPK A;  5GPG A;  2LJ4 A;  4ODO A;  2KFW A;  4Z2J A;  3RM8 A;  3WD1 A;  4TNS A;  2MNT A;  4TW8 A;  4TW6 A;  2DPE A;  4Z2K A;  5HWB A;  2PV1 A;  1F8A B;  5JH8 A;  1SYT A;  1O6I A;  1M5Y A;  1W1V A;  4ODR A;  3WKZ A;  4XAK A;  3O5Q A;  3WD2 A;  1QPL A;  4DWS A;  2KGJ A;  2KE0 A;  4DH0 A;  4R5E A;  3CGM A;  4WKH A;  3ARW A;  1WAW A;  4ZPV R;  4DWS D;  3ARS A;  4NZC A;  3LUO A;  5B8I C;  2MLX A;  2RUR A;  1T11 A;  2DT1 A;  3FY1 A;  1FFR A;  1LQ0 A;  1NWU A;  3WL1 A;  1EIB A;  1ROU A;  1JNT A;  1E6R A;  2ZQT A;  1FFQ A;  2IUZ A;  1PBK A;  1YAT A;  3AS0 A;  4ODM A;  2FDM A;  1NSG A;  2MLZ A;  2PPO A;  4W5U A;  3KAI A;  5GQB A;  2XP9 A;  1FKJ A;  2IF4 A;  2A3E A;  1F40 A;  4Z2L A;  1UR8 A;  2XP7 A;  4U85 A;  2PV3 A;  4Q7N A;  4G2P A;  1E6Z A;  4U86 A;  1NMW A;  3RFW A;  3KCE A;  2LKN A;  4DWS C;  4JFI A;  2FAP A;  3W4R A;  4ODP A;  1FKK A;  1Q6H A;  3O5P A;  3CHF A;  3O5L A;  3ARX A;  3KAG A;  4LAY A;  3O5E A;  1E15 A;  3BXW A;  3O5O A;  3H9R B;  3OA5 A;  2PI6 A;  5HT1 A;  1OGB A;  2WM0 A;  4DRJ A;  4C02 B;  3CHC A;  1EHN A;  1X6L A;  4ZPW R;  1P5Q A;  1H0I A;  4ITZ A;  2OLH A;  1E9L A;  3ART A;  4MTV A;  4TYO A;  1KT0 A;  4Z2G A;  4URI A;  3JXV A;  1JND A;  3CHD A;  2PV2 A;  3KAF A;  3O5R A;  3NTP A;  3B8S A;  2DSW A;  4MGV A;  4LAV A;  2F21 A;  3WL0 A;  1HJV A;  3G6L A;  4J4O A;  2FKE A;  4WKA A;  1D2K A;  4IPX A;  1W9V A;  1CTN A;  3PR9 A;  4WJX A;  2JZV A;  3WIJ A;  1HKI A;  1D7I A;  3AS1 A;  3O5K A;  2XPB A;  4HBO A;  3WQV A;  3NI6 A;  3MDY B;  2WLZ A;  3FXY A;  4L72 B;  3UI6 A;  2ZR5 A;  1FKD A;  1R9H A;  1HXV A;  1HJX A;  1NWT A;  1D6O A;  1ZBK A;  3CZ8 A;  4JFL A;  2Q5A A;  4ODL A;  2ESC A;  3WD3 A;  3PRD A;  3ARQ A;  4IQ2 A;  1SR0 A;  3IK8 A;  5BXJ A;  4HBE A;  1ZBV A;  1U79 A;  4NSB A;  3CH9 A;  5HWC A;  3B7X A;  3RM4 A;  4KR0 B;  1FAP A;  3FAP A;  3KAH A;  4ML4 A;  1NWS A;  1QPF A;  3ARV A;  4AY1 A;  1ZBC A;  1W1P A;  4ODQ A;  1UR9 A;  2XP5 A;  1W1T A;  2ZQS A;  1B6C A;  4PTM A;  5J6E A;  2O92 A;  1W9P A;  1EYM A;  3G6M A;  1XRV A;  5HW8 A;  1ZL1 A;  4P8X A;  1J4R A;  3B9A A;  1E6P A;  4W9P A;  1Q6U A;  1FKL A;  3GPK A;  4WIW A;  1YW5 A;  2K8I A;  3VAW A;  4HAR A;  4L3N A;  4DRK A;  3WD4 A;  1ITX A;  2A3A A;  3O5J A;  2B31 A;  1FD9 A;  1QZ2 A;  4TX0 A;  3WQW A;  2YBU A;  2G41 A;  3O5D A;  1OGG A;  1ROT A;  1TCO C;  4JFK A;  1LL7 A;  1BKF A;  1HKK A;  4S3K A;  4DRO A;  4LAW A;  2DG4 A;  1GUV A;  3CHE A;  4QIB A;  2RUQ A;  4GIV A;  1FKF A;  3ARZ A;  4GGQ A;  4FAP A;  2DT0 A;  4O2T A;  4IT4 A;  5DIV A;  1FKG A;  1LL4 A;  2MPH A;  4WKF A;  1VF8 A;  4MAV A;  4JFM A;  2PBC A;  1XHG A;  2XP3 A;  4IT6 A;  2LPV A;  1TFV A;  1FKT A;  2M2A A;  2DSU A;  2RSE A;  3B9D A;  1J6Y A;  1N1A A;  3UI5 A;  3O5G A;  2DG9 A;  1D7H A;  3ARY A;  2KI3 A;  2DT3 A;  4JYS A;  2MLY A;  3EY6 A;  1C9H A;  1FKI A;  2M1I A;  2ZQU A;  2WK2 A;  2D9F A;  2DSV A;  3UQA A;  3UQB A;  3O5F A;  3KAB A;  4DRI A;  1EDQ A;  4N19 A;  1HKM A;  1J4H A;  4Z2H A;  1FJD A;  4W9O A;  1NWR A;  1WNO A;  2PPP A;  4QZV B;  3CGN A;  3PRA A;  1LJY A;  3IKD A;  4ODK A;  1Y0O A;  2Y78 A;  4G50 A;  3I6C A;  5HW7 A;  5DO2 A;  2DT2 A;  2L2S A;  2LGO A;  4DWS B;  2A3B A;  3JYM A;  3B9E A;  4MSP A;  2VCD A;  1A7X A;  3WD0 A;  3AQU A;  3PRB A;  1GPF A;  1FKR A;  2YBT A;  5I98 A;  4MNL A;  2QF8 A;  1E6N A;  1LG1 A;  3ODK A;  2ZR6 A;  4WK9 A;  3QOK A;  4Z2I A;  1PIN A;  3ALG A;  1HJW A;  4P8W A;  3NRK A;  4ZS6 A;  4Q22 A;  4IQC A;  1FKB A;  1K9T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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