4DROA

Evaluation of synthetic fk506 analogs as ligands for fkbp51 and fkbp52: complex of fkbp51 with (1r)-3-(3,4-dimethoxyphenyl)-1-phenylpropyl (2s)-1-{[(1r,2s)-2-ethyl-1-hydroxycyclohexyl](oxo)acetyl}piperidine-2-carboxylate
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
128
structure length
128
Chain Sequence
GAPATVTEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52.
pubmed doi rcsb
molecule tags Isomerase
source organism Homo sapiens
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP5
total genus 36
structure length 128
sequence length 128
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2012-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00254 FKBP_C FKBP-type peptidyl-prolyl cis-trans isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.50.40 Alpha Beta Roll Chitinase A; domain 3 Chitinase A; domain 3 4droA00
2PBCA 4ODPA 2PPOA 4DRJA 2IF4A 2ZQTA 4DRKA 4FN2A 1FKSA 3O5EA 4TW6A 2DG9A 2L2SA 3O5FA 4DRNA 2Q5AA 4TYOA 1JNSA 3O5LA 1F8AB 2F2DA 2LPVA 3O5KA 2XP5A 3O5MA 3FAPA 1JVWA 1J4RA 1JNTA 1FD9A 4LAYA 1TCOC 3ODKA 2XP7A 4LAXA 5HW8A 4DZ3A 3MDYB 4MSPA 1FKLA 2MNTA 2FAPA 1QPLA 4DH0A 5HW7A 1C9HA 3O5OA 1NSGA 1YW5A 3O5DA 4DRMA 4JFIA 5HWCA 2M08A 1YATA 4TW7A 1D6OA 1P5QA 1KT0A 4U86A 1ROUA 4W9PA 5GPGA 3PRDA 1FJDA 3IK8A 3EY6A 3NRKA 5J6EA 3O5GA 2DG3A 3O5IA 2ZR5A 1W26A 4ITZA 4ODRA 3NI6A 3PRBA 2ITKA 2ZQVA 2KE0A 3JYMA 4G50A 1FKHA 2XPBA 4GGQA 4QT3A 4QT2A 1FKRA 1QZ2A 1J4IA 3WH0A 1M5YA 1D7JA 2MLZA 5HUAA 1FKKA 2MF9A 3KACA 4JFLA 4W9QA 4MGVA 4R0XA 5HTGA 1B6CA 4U85A 2LGOA 1EYMA 2ZQUA 4IPXA 3UI6A 2F4EA 4DT4A 4DROA 1FKJA 2RURA 5DITA 2RUQA 2PV2A 2JZVA 2KGJA 4ODKA 3UQIA 4FAPA 2XP3A 1PBKA 5I98A 4DRIA 4ODOA 1PINA 3TDBA 3NTPA 4JYSA 2F21A 1ZK6A 4DIPA 2AWGA 1NMWA 2MLYA 2PPNA 4ODMA 2MPHA 4JFKA 2K8IA 3VAWA 4DRPA 2PV1A 4IQ2A 3O5PA 4GIVA 2XP6A 2LKNA 3KCEA 2RSEA 2UZ5A 1L1PA 2N87A 3OOBA 1U79A 2MLXA 3RGCA 5D75A 2PPPA 1N1AA 1EQ3A 1Q6HA 1F40A 1ROTA 4G2PA 1Q6UA 2FKEA 2XPAA 3O5RA 2RUDA 3KAGA 2ZQSA 1D7IA 3KAIA 3O5QA 3IKDA 1FKFA 2OFNA 4JFJA 1FKDA 5HW6A 3UI4A 4TX0A 4IQCA 3JXVA 1R9HA 4J4OA 2KFWA 4DRQA 4ODQA 3GPKA 4O2TA 3I6CA 4ODLA 5HT1A 2LJ4A 4DZ2A 1J4HA 4LAWA 1FKGA 3KZ7A 3O5JA 1HXVA 3JYJA 3H9RB 5DIUA 3KABA 1ZCNA 5B8IC 5DIVA 4N19A 3UI5A 4ODNA 2KO7A 1FKBA 3TCZA 2D9FA 1FKTA 2RQSA 4QIBA 3IKGA 4W9OA 4C02B 2KR7A 2PV3A 3KAFA 4NNRA 1A7XA 3B7XA 3UQBA 3KADA 2XP4A 3CGMA 1D7HA 1J6YA 1FAPA 1T11A 2ZR6A 3IHZA 1KT1A 4J4NA 1NMVA 1BL4A 3LUOA 4U84A 3KAHA 3RFWA 3TC5A 5HWBA 2Y78A 3CGNA 4TW8A 2RUCA 2XP8A 4LAVA 3UF8A 5HKGA 4DRHA 2M1IA 2VN1A 3UQAA 1Y0OA 2KI3A 2VCDA 2DG4A 4TNSA 5BXJA 1BKFA 2ZR4A 1Q1CA 3PA7A 4JFMA 4BF8A 2M2AA 1QPFA 1FKIA 2XP9A 1Q6IA
chains in the Genus database with same CATH superfamily
3WKZA 1JNEA 2F23A 2L2SA 3O5FA 1FFQA 2Q5AA 1JNSA 4WKAA 1XRVA 2XP5A 3O5MA 1W9PA 2DSUA 3QOKA 2O9OA 4LAXA 5HW8A 4LGXA 2FAPA 1QPLA 1O6IA 1OGBA 3WL1A 1GUVA 4TW7A 4DWSC 4WKHA 3W4RA 3PRAA 3PRDA 3NRKA 1W26A 2DPEA 3B9EA 2ITKA 2KE0A 3JYMA 3WH0A 4S3KA 1D7JA 4Q22A 4JFLA 4MGVA 4R0XA 5DEZA 2A3AA 2LGOA 2F4EA 2RURA 1UR8A 2PV2A 4MNJA 3FY1A 4FAPA 5I98A 1PINA 3NTPA 1CTNA 1LL4A 3ARVA 2K8IA 3KCEA 3CHCA 1GOIA 1Q6HA 1SYTA 2RUDA 2ZQSA 1FKFA 4JFJA 1FKDA 3UI4A 4IQCA 4DWSD 4WK9A 1R9HA 4J4OA 2YBUA 1HJVA 4DRQA 4ODQA 3GPKA 1X6NA 2LJ4A 4LAWA 3O5JA 4MNKA 3WQWA 3ARPA 1HXVA 4ODNA 2KO7A 4QIBA 3AQUA 1A7XA 3KADA 2XP4A 4WKFA 1D7HA 5GQBA 1LL6A 1SR0A 3RFWA 3G6MA 4J4NA 3TC5A 4XAKA 4U84A 5HWBA 2Y78A 2RUCA 2XP8A 3UF8A 2M1IA 3ARTA 3B9AA 2DG4A 4Z2GA 2ZR4A 4BF8A 3WD4A 4P8XA 2M2AA 1EIBA 2XP9A 2ZQTA 1NWUA 1OWQA 1W1YA 3WD3A 2OLHA 4TYOA 4DRNA 3EIPA 2LPVA 3O5KA 1X6LA 4WJXA 1NH6A 2DT1A 1ITXA 1RD6A 1W9VA 4DZ3A 4Z2LA 3FXYA 4UDMA 5HW7A 1C9HA 3O5OA 5HWCA 4JFIA 1YATA 2B31A 1P5QA 5GPGA 4Z2IA 3IK8A 2ETNA 5J6EA 3O5IA 4ITZA 1E6NA 3NI6A 1E44A 5GPRA 1HKJA 4G50A 2XPBA 3ARWA 5DO2A 1M5YA 1LG2A 2MLZA 4P8VA 5HUAA 1FKKA 4W9QA 3ARSA 4HARA 1B6CA 4DT4A 1EYMA 2ZQUA 4IPXA 1FKJA 2RUQA 2KGJA 2XP3A 3ALFA 4JYSA 1ZK6A 3RM9A 2AWGA 2FDMA 2PPNA 3ARQA 1JNDA 2XP6A 1L1PA 1ZBCA 3OOBA 2MLXA 1EQ3A 1N1AA 2G8ZA 1F40A 1ROTA 4G2PA 2FKEA 2DT2A 3O5RA 3KAGA 1D7IA 2OFNA 5HW6A 2DT0A 4DWSA 4Z2JA 3CZ8A 5HBFA 4O2TA 3I6CA 5HT1A 1J4HA 3KZ7A 4NZCA 4S3JA 3TCZA 1GPFA 4W9OA 2PV3A 3KAFA 4NNRA 1IX5A 2WLZA 1FAPA 2ZR6A 1KT1A 2YBTA 1BL4A 3WD0A 4PTMA 1H0GA 4LAVA 1NWSA 2VN1A 2VCDA 1Q1CA 4URIA 1QPFA 3IHZA 1FKIA 1Q6IA 3ODKA 2DSZA 2PI6A 2DSWA 3WQVA 4DRJA 1LQ0A 2IF4A 4DRKA 3WIJA 4FN2A 1FKSA 4TW6A 4MAVA 2EULA 3WD2A 3FAPA 1JVWA 1J4RA 1FD9A 1HJWA 3ALGA 3GU0A 1E6ZA 3MDYB 4HBEA 3PR9A 3CHDA 3AS2A 4DH0A 3ARZA 4QZVB 1NSGA 1YW5A 3O5DA 4IT6A 2WM0A 2M08A 1D6OA 1ROUA 1W1VA 3ARRA 4WIWA 1FJDA 3EY6A 2ZR5A 3PRBA 2ZQVA 2WK2A 4ML4A 4KR0B 3KACA 5HTGA 1LG1A 2ESCA 3G6LA 2JZVA 1JCHB 1H0IA 1WB0A 4ODKA 3UQIA 2G41A 4ODOA 1E6RA 3TDBA 1NMWA 1W9UA 2MPHA 4JFKA 1NWTA 4DRPA 1TFVA 1OGGA 2PV1A 1LJYA 3AS3A 2A3BA 5D75A 1ZBWA 3OA5A 3KAIA 5JH8A 4MNMA 3CH9A 2O92A 3JXVA 2KFWA 4MNLA 4ODLA 4ZPTR 1FKGA 3JYJA 1ZB5A 3H9RB 3KABA 1ZCNA 1HKKA 5DIUA 5DIVA 2PN0A 3UI5A 2QF8A 2B5UB 1FKBA 1FKTA 2RQSA 4ZPVR 3B7XA 3UQBA 3RM8A 1J6YA 1T11A 2AOSA 1LL7A 1ZBVA 4DWSB 3CGNA 2A3CA 4L72B 3B9DA 3UQAA 3ARXA 1Y0OA 2KI3A 5BXJA 4ZS6A 1BKFA 4JFMA 3PA7A 1HKMA 2PBCA 4ODPA 2PPOA 3O5EA 2DG9A 4W5UA 1FFRA 3O5LA 1F8AB 2F2DA 3WL0A 4R5EA 1JNTA 4LAYA 1TCOC 2XP7A 4MSPA 1FKLA 2MNTA 3BMBA 4DRMA 4Z2HA 1VF8A 3ARYA 1KT0A 4U86A 4W9PA 3O5GA 2DG3A 2DT3A 3AROA 4ODRA 2A3EA 1ZU8A 4GGQA 1FKHA 4QT3A 4QT2A 1FKRA 1QZ2A 1J4IA 4Q7NA 3B8SA 1ZBKA 2MF9A 4HBOA 4L3NA 1W1TA 3BXWA 2DSVA 4Z2KA 4U85A 3UI6A 2WLYA 1XHGA 4DROA 5DITA 1NWRA 3RMEA 1PBKA 4DRIA 4P8UA 2F21A 4DIPA 2MLYA 4ODMA 3VAWA 4IQ2A 3O5PA 4GIVA 2LKNA 1UR9A 2RSEA 2UZ5A 2N87A 5DF0A 1U79A 3CHEA 3RGCA 2PPPA 1W1PA 1Q6UA 3AS0A 1E6PA 4MPKA 2XPAA 3O5QA 1EDQA 3IKDA 4TX0A 3RM4A 1HJXA 3WD1A 1K9TA 4IT4A 4DZ2A 2P4VA 4MTVA 4NSBA 5B8IC 3ARUA 1E9LA 1D2KA 4N19A 1ZL1A 2D9FA 4C02B 1EHNA 3IKGA 2KR7A 3CGMA 3AS1A 1HKIA 4KQZA 3LUOA 1NMVA 3CHFA 3KAHA 1E15A 1GRJA 4TW8A 4P8WA 3GTYX 1WAWA 5HKGA 4DRHA 1WNOA 4AY1A 4TNSA 2IUZA 1KFWA 4ZPWR
chains in the Genus database with same CATH topology
3WKZA 1JNEA 2L2SA 3O5FA 1FFQA 2Q5AA 1JNSA 4WKAA 1XRVA 2XP5A 3O5MA 1W9PA 2DSUA 3QOKA 2O9OA 4LAXA 5HW8A 4LGXA 2FAPA 1QPLA 1O6IA 1OGBA 3WL1A 1GUVA 4TW7A 4DWSC 4WKHA 3W4RA 3PRAA 3PRDA 3NRKA 1W26A 2DPEA 3B9EA 2ITKA 2KE0A 3JYMA 3WH0A 4S3KA 1D7JA 4Q22A 4JFLA 4MGVA 4R0XA 5DEZA 2A3AA 2LGOA 2F4EA 2RURA 1UR8A 2PV2A 4MNJA 3FY1A 4FAPA 5I98A 1PINA 3NTPA 1CTNA 1LL4A 3ARVA 2K8IA 3KCEA 3CHCA 1GOIA 1Q6HA 1SYTA 2RUDA 2ZQSA 1FKFA 4JFJA 1FKDA 3UI4A 4IQCA 4DWSD 4WK9A 1R9HA 4J4OA 2YBUA 1HJVA 4DRQA 4ODQA 3GPKA 1X6NA 2LJ4A 4LAWA 3O5JA 4MNKA 3WQWA 3ARPA 1HXVA 4ODNA 2KO7A 4QIBA 3AQUA 1A7XA 3KADA 2XP4A 4WKFA 1D7HA 5GQBA 1LL6A 1SR0A 3RFWA 3G6MA 4J4NA 3TC5A 4XAKA 4U84A 5HWBA 2Y78A 2RUCA 2XP8A 3UF8A 2M1IA 3ARTA 3B9AA 2DG4A 4Z2GA 2ZR4A 4BF8A 3WD4A 4P8XA 2M2AA 1EIBA 2XP9A 2ZQTA 1NWUA 1OWQA 1W1YA 3WD3A 2OLHA 4TYOA 4DRNA 2LPVA 3O5KA 1X6LA 4WJXA 1NH6A 2DT1A 1ITXA 1RD6A 1W9VA 4DZ3A 4Z2LA 3FXYA 5HW7A 1C9HA 3O5OA 5HWCA 4JFIA 1YATA 2B31A 1P5QA 5GPGA 4Z2IA 3IK8A 5J6EA 3O5IA 4ITZA 1E6NA 3NI6A 5GPRA 1HKJA 4G50A 2XPBA 3ARWA 5DO2A 1M5YA 1LG2A 2MLZA 4P8VA 5HUAA 1FKKA 4W9QA 3ARSA 4HARA 1B6CA 4DT4A 1EYMA 2ZQUA 4IPXA 1FKJA 2RUQA 2KGJA 2XP3A 3ALFA 4JYSA 1ZK6A 3RM9A 2AWGA 2FDMA 2PPNA 3ARQA 1JNDA 2XP6A 1L1PA 1ZBCA 3OOBA 2MLXA 1EQ3A 1N1AA 2G8ZA 1F40A 1ROTA 4G2PA 2FKEA 2DT2A 3O5RA 3KAGA 1D7IA 2OFNA 5HW6A 2DT0A 4DWSA 4Z2JA 3CZ8A 5HBFA 4O2TA 3I6CA 5HT1A 1J4HA 3KZ7A 4NZCA 4S3JA 3TCZA 1GPFA 4W9OA 2PV3A 3KAFA 4NNRA 1IX5A 2WLZA 1FAPA 2ZR6A 1KT1A 2YBTA 1BL4A 3WD0A 4PTMA 1H0GA 4LAVA 1NWSA 2VN1A 2VCDA 1Q1CA 4URIA 1QPFA 3IHZA 1FKIA 1Q6IA 3ODKA 2DSZA 2PI6A 2DSWA 3WQVA 4DRJA 1LQ0A 2IF4A 4DRKA 3WIJA 4FN2A 1FKSA 4TW6A 4MAVA 3WD2A 3FAPA 1JVWA 1J4RA 1FD9A 1HJWA 3ALGA 1E6ZA 3MDYB 4HBEA 3PR9A 3CHDA 3AS2A 4DH0A 3ARZA 4QZVB 1NSGA 1YW5A 3O5DA 4IT6A 2WM0A 2M08A 1D6OA 1ROUA 1W1VA 3ARRA 4WIWA 1FJDA 3EY6A 2ZR5A 3PRBA 2ZQVA 2WK2A 4ML4A 4KR0B 3KACA 5HTGA 1LG1A 2ESCA 3G6LA 2JZVA 1H0IA 1WB0A 4ODKA 3UQIA 2G41A 4ODOA 1E6RA 3TDBA 1NMWA 1W9UA 2MPHA 4JFKA 1NWTA 4DRPA 1TFVA 1OGGA 2PV1A 1LJYA 3AS3A 2A3BA 5D75A 1ZBWA 3OA5A 3KAIA 5JH8A 4MNMA 3CH9A 2O92A 3JXVA 2KFWA 4MNLA 4ODLA 4ZPTR 1FKGA 3JYJA 1ZB5A 3H9RB 3KABA 1ZCNA 1HKKA 5DIUA 5DIVA 3UI5A 2QF8A 1FKBA 1FKTA 2RQSA 4ZPVR 3B7XA 3UQBA 3RM8A 1J6YA 1T11A 2AOSA 1LL7A 1ZBVA 4DWSB 3CGNA 2A3CA 4L72B 3B9DA 3UQAA 3ARXA 1Y0OA 2KI3A 5BXJA 4ZS6A 1BKFA 4JFMA 3PA7A 1HKMA 2PBCA 4ODPA 2PPOA 3O5EA 2DG9A 4W5UA 1FFRA 3O5LA 1F8AB 2F2DA 3WL0A 4R5EA 1JNTA 4LAYA 1TCOC 2XP7A 4MSPA 1FKLA 2MNTA 4DRMA 4Z2HA 1VF8A 3ARYA 1KT0A 4U86A 4W9PA 3O5GA 2DG3A 2DT3A 3AROA 4ODRA 2A3EA 1ZU8A 4GGQA 1FKHA 4QT3A 4QT2A 1FKRA 1QZ2A 1J4IA 4Q7NA 3B8SA 1ZBKA 2MF9A 4HBOA 4L3NA 1W1TA 3BXWA 2DSVA 4Z2KA 4U85A 3UI6A 2WLYA 1XHGA 4DROA 5DITA 1NWRA 3RMEA 1PBKA 4DRIA 4P8UA 2F21A 4DIPA 2MLYA 4ODMA 3VAWA 4IQ2A 3O5PA 4GIVA 2LKNA 1UR9A 2RSEA 2UZ5A 2N87A 5DF0A 1U79A 3CHEA 3RGCA 2PPPA 1W1PA 1Q6UA 3AS0A 1E6PA 4MPKA 2XPAA 3O5QA 1EDQA 3IKDA 4TX0A 3RM4A 1HJXA 3WD1A 1K9TA 4IT4A 4DZ2A 4MTVA 4NSBA 5B8IC 3ARUA 1E9LA 1D2KA 4N19A 1ZL1A 2D9FA 4C02B 1EHNA 3IKGA 2KR7A 3CGMA 3AS1A 1HKIA 4KQZA 1NMVA 3CHFA 3LUOA 3KAHA 1E15A 4TW8A 4P8WA 1WAWA 5HKGA 4DRHA 1WNOA 4AY1A 4TNSA 2IUZA 1KFWA 4ZPWR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PBC A;  4ODP A;  2PPO A;  4DRJ A;  2IF4 A;  2ZQT A;  4DRK A;  4FN2 A;  1FKS A;  3O5E A;  4TW6 A;  2DG9 A;  2L2S A;  3O5F A;  4DRN A;  2Q5A A;  4TYO A;  1JNS A;  3O5L A;  1F8A B;  2F2D A;  2LPV A;  3O5K A;  2XP5 A;  3O5M A;  3FAP A;  1JVW A;  1J4R A;  1JNT A;  1FD9 A;  4LAY A;  1TCO C;  3ODK A;  2XP7 A;  4LAX A;  5HW8 A;  4DZ3 A;  3MDY B;  4MSP A;  1FKL A;  2MNT A;  2FAP A;  1QPL A;  4DH0 A;  5HW7 A;  1C9H A;  3O5O A;  1NSG A;  1YW5 A;  3O5D A;  4DRM A;  4JFI A;  5HWC A;  2M08 A;  1YAT A;  4TW7 A;  1D6O A;  1P5Q A;  1KT0 A;  4U86 A;  1ROU A;  4W9P A;  5GPG A;  3PRD A;  1FJD A;  3IK8 A;  3EY6 A;  3NRK A;  5J6E A;  3O5G A;  2DG3 A;  3O5I A;  2ZR5 A;  1W26 A;  4ITZ A;  4ODR A;  3NI6 A;  3PRB A;  2ITK A;  2ZQV A;  2KE0 A;  3JYM A;  4G50 A;  1FKH A;  2XPB A;  4GGQ A;  4QT3 A;  4QT2 A;  1FKR A;  1QZ2 A;  1J4I A;  3WH0 A;  1M5Y A;  1D7J A;  2MLZ A;  5HUA A;  1FKK A;  2MF9 A;  3KAC A;  4JFL A;  4W9Q A;  4MGV A;  4R0X A;  5HTG A;  1B6C A;  4U85 A;  2LGO A;  1EYM A;  2ZQU A;  4IPX A;  3UI6 A;  2F4E A;  4DT4 A;  4DRO A;  1FKJ A;  2RUR A;  5DIT A;  2RUQ A;  2PV2 A;  2JZV A;  2KGJ A;  4ODK A;  3UQI A;  4FAP A;  2XP3 A;  1PBK A;  5I98 A;  4DRI A;  4ODO A;  1PIN A;  3TDB A;  3NTP A;  4JYS A;  2F21 A;  1ZK6 A;  4DIP A;  2AWG A;  1NMW A;  2MLY A;  2PPN A;  4ODM A;  2MPH A;  4JFK A;  2K8I A;  3VAW A;  4DRP A;  2PV1 A;  4IQ2 A;  3O5P A;  4GIV A;  2XP6 A;  2LKN A;  3KCE A;  2RSE A;  2UZ5 A;  1L1P A;  2N87 A;  3OOB A;  1U79 A;  2MLX A;  3RGC A;  5D75 A;  2PPP A;  1N1A A;  1EQ3 A;  1Q6H A;  1F40 A;  1ROT A;  4G2P A;  1Q6U A;  2FKE A;  2XPA A;  3O5R A;  2RUD A;  3KAG A;  2ZQS A;  1D7I A;  3KAI A;  3O5Q A;  3IKD A;  1FKF A;  2OFN A;  4JFJ A;  1FKD A;  5HW6 A;  3UI4 A;  4TX0 A;  4IQC A;  3JXV A;  1R9H A;  4J4O A;  2KFW A;  4DRQ A;  4ODQ A;  3GPK A;  4O2T A;  3I6C A;  4ODL A;  5HT1 A;  2LJ4 A;  4DZ2 A;  1J4H A;  4LAW A;  1FKG A;  3KZ7 A;  3O5J A;  1HXV A;  3JYJ A;  3H9R B;  5DIU A;  3KAB A;  1ZCN A;  5B8I C;  5DIV A;  4N19 A;  3UI5 A;  4ODN A;  2KO7 A;  1FKB A;  3TCZ A;  2D9F A;  1FKT A;  2RQS A;  4QIB A;  3IKG A;  4W9O A;  4C02 B;  2KR7 A;  2PV3 A;  3KAF A;  4NNR A;  1A7X A;  3B7X A;  3UQB A;  3KAD A;  2XP4 A;  3CGM A;  1D7H A;  1J6Y A;  1FAP A;  1T11 A;  2ZR6 A;  3IHZ A;  1KT1 A;  4J4N A;  1NMV A;  1BL4 A;  3LUO A;  4U84 A;  3KAH A;  3RFW A;  3TC5 A;  5HWB A;  2Y78 A;  3CGN A;  4TW8 A;  2RUC A;  2XP8 A;  4LAV A;  3UF8 A;  5HKG A;  4DRH A;  2M1I A;  2VN1 A;  3UQA A;  1Y0O A;  2KI3 A;  2VCD A;  2DG4 A;  4TNS A;  5BXJ A;  1BKF A;  2ZR4 A;  1Q1C A;  3PA7 A;  4JFM A;  4BF8 A;  2M2A A;  1QPF A;  1FKI A;  2XP9 A;  1Q6I A; 
#chains in the Genus database with same CATH topology
 3WKZ A;  1JNE A;  2F23 A;  2L2S A;  3O5F A;  1FFQ A;  2Q5A A;  1JNS A;  4WKA A;  1XRV A;  2XP5 A;  3O5M A;  1W9P A;  2DSU A;  3QOK A;  2O9O A;  4LAX A;  5HW8 A;  4LGX A;  2FAP A;  1QPL A;  1O6I A;  1OGB A;  3WL1 A;  1GUV A;  4TW7 A;  4DWS C;  4WKH A;  3W4R A;  3PRA A;  3PRD A;  3NRK A;  1W26 A;  2DPE A;  3B9E A;  2ITK A;  2KE0 A;  3JYM A;  3WH0 A;  4S3K A;  1D7J A;  4Q22 A;  4JFL A;  4MGV A;  4R0X A;  5DEZ A;  2A3A A;  2LGO A;  2F4E A;  2RUR A;  1UR8 A;  2PV2 A;  4MNJ A;  3FY1 A;  4FAP A;  5I98 A;  1PIN A;  3NTP A;  1CTN A;  1LL4 A;  3ARV A;  2K8I A;  3KCE A;  3CHC A;  1GOI A;  1Q6H A;  1SYT A;  2RUD A;  2ZQS A;  1FKF A;  4JFJ A;  1FKD A;  3UI4 A;  4IQC A;  4DWS D;  4WK9 A;  1R9H A;  4J4O A;  2YBU A;  1HJV A;  4DRQ A;  4ODQ A;  3GPK A;  1X6N A;  2LJ4 A;  4LAW A;  3O5J A;  4MNK A;  3WQW A;  3ARP A;  1HXV A;  4ODN A;  2KO7 A;  4QIB A;  3AQU A;  1A7X A;  3KAD A;  2XP4 A;  4WKF A;  1D7H A;  5GQB A;  1LL6 A;  1SR0 A;  3RFW A;  3G6M A;  4J4N A;  3TC5 A;  4XAK A;  4U84 A;  5HWB A;  2Y78 A;  2RUC A;  2XP8 A;  3UF8 A;  2M1I A;  3ART A;  3B9A A;  2DG4 A;  4Z2G A;  2ZR4 A;  4BF8 A;  3WD4 A;  4P8X A;  2M2A A;  1EIB A;  2XP9 A;  2ZQT A;  1NWU A;  1OWQ A;  1W1Y A;  3WD3 A;  2OLH A;  4TYO A;  4DRN A;  3EIP A;  2LPV A;  3O5K A;  1X6L A;  4WJX A;  1NH6 A;  2DT1 A;  1ITX A;  1RD6 A;  1W9V A;  4DZ3 A;  4Z2L A;  3FXY A;  4UDM A;  5HW7 A;  1C9H A;  3O5O A;  5HWC A;  4JFI A;  1YAT A;  2B31 A;  1P5Q A;  5GPG A;  4Z2I A;  3IK8 A;  2ETN A;  5J6E A;  3O5I A;  4ITZ A;  1E6N A;  3NI6 A;  1E44 A;  5GPR A;  1HKJ A;  4G50 A;  2XPB A;  3ARW A;  5DO2 A;  1M5Y A;  1LG2 A;  2MLZ A;  4P8V A;  5HUA A;  1FKK A;  4W9Q A;  3ARS A;  4HAR A;  1B6C A;  4DT4 A;  1EYM A;  2ZQU A;  4IPX A;  1FKJ A;  2RUQ A;  2KGJ A;  2XP3 A;  3ALF A;  4JYS A;  1ZK6 A;  3RM9 A;  2AWG A;  2FDM A;  2PPN A;  3ARQ A;  1JND A;  2XP6 A;  1L1P A;  1ZBC A;  3OOB A;  2MLX A;  1EQ3 A;  1N1A A;  2G8Z A;  1F40 A;  1ROT A;  4G2P A;  2FKE A;  2DT2 A;  3O5R A;  3KAG A;  1D7I A;  2OFN A;  5HW6 A;  2DT0 A;  4DWS A;  4Z2J A;  3CZ8 A;  5HBF A;  4O2T A;  3I6C A;  5HT1 A;  1J4H A;  3KZ7 A;  4NZC A;  4S3J A;  3TCZ A;  1GPF A;  4W9O A;  2PV3 A;  3KAF A;  4NNR A;  1IX5 A;  2WLZ A;  1FAP A;  2ZR6 A;  1KT1 A;  2YBT A;  1BL4 A;  3WD0 A;  4PTM A;  1H0G A;  4LAV A;  1NWS A;  2VN1 A;  2VCD A;  1Q1C A;  4URI A;  1QPF A;  3IHZ A;  1FKI A;  1Q6I A;  3ODK A;  2DSZ A;  2PI6 A;  2DSW A;  3WQV A;  4DRJ A;  1LQ0 A;  2IF4 A;  4DRK A;  3WIJ A;  4FN2 A;  1FKS A;  4TW6 A;  4MAV A;  2EUL A;  3WD2 A;  3FAP A;  1JVW A;  1J4R A;  1FD9 A;  1HJW A;  3ALG A;  3GU0 A;  1E6Z A;  3MDY B;  4HBE A;  3PR9 A;  3CHD A;  3AS2 A;  4DH0 A;  3ARZ A;  4QZV B;  1NSG A;  1YW5 A;  3O5D A;  4IT6 A;  2WM0 A;  2M08 A;  1D6O A;  1ROU A;  1W1V A;  3ARR A;  4WIW A;  1FJD A;  3EY6 A;  2ZR5 A;  3PRB A;  2ZQV A;  2WK2 A;  4ML4 A;  4KR0 B;  3KAC A;  5HTG A;  1LG1 A;  2ESC A;  3G6L A;  2JZV A;  1JCH B;  1H0I A;  1WB0 A;  4ODK A;  3UQI A;  2G41 A;  4ODO A;  1E6R A;  3TDB A;  1NMW A;  1W9U A;  2MPH A;  4JFK A;  1NWT A;  4DRP A;  1TFV A;  1OGG A;  2PV1 A;  1LJY A;  3AS3 A;  2A3B A;  5D75 A;  1ZBW A;  3OA5 A;  3KAI A;  5JH8 A;  4MNM A;  3CH9 A;  2O92 A;  3JXV A;  2KFW A;  4MNL A;  4ODL A;  4ZPT R;  1FKG A;  3JYJ A;  1ZB5 A;  3H9R B;  3KAB A;  1ZCN A;  1HKK A;  5DIU A;  5DIV A;  2PN0 A;  3UI5 A;  2QF8 A;  2B5U B;  1FKB A;  1FKT A;  2RQS A;  4ZPV R;  3B7X A;  3UQB A;  3RM8 A;  1J6Y A;  1T11 A;  2AOS A;  1LL7 A;  1ZBV A;  4DWS B;  3CGN A;  2A3C A;  4L72 B;  3B9D A;  3UQA A;  3ARX A;  1Y0O A;  2KI3 A;  5BXJ A;  4ZS6 A;  1BKF A;  4JFM A;  3PA7 A;  1HKM A;  2PBC A;  4ODP A;  2PPO A;  3O5E A;  2DG9 A;  4W5U A;  1FFR A;  3O5L A;  1F8A B;  2F2D A;  3WL0 A;  4R5E A;  1JNT A;  4LAY A;  1TCO C;  2XP7 A;  4MSP A;  1FKL A;  2MNT A;  3BMB A;  4DRM A;  4Z2H A;  1VF8 A;  3ARY A;  1KT0 A;  4U86 A;  4W9P A;  3O5G A;  2DG3 A;  2DT3 A;  3ARO A;  4ODR A;  2A3E A;  1ZU8 A;  4GGQ A;  1FKH A;  4QT3 A;  4QT2 A;  1FKR A;  1QZ2 A;  1J4I A;  4Q7N A;  3B8S A;  1ZBK A;  2MF9 A;  4HBO A;  4L3N A;  1W1T A;  3BXW A;  2DSV A;  4Z2K A;  4U85 A;  3UI6 A;  2WLY A;  1XHG A;  4DRO A;  5DIT A;  1NWR A;  3RME A;  1PBK A;  4DRI A;  4P8U A;  2F21 A;  4DIP A;  2MLY A;  4ODM A;  3VAW A;  4IQ2 A;  3O5P A;  4GIV A;  2LKN A;  1UR9 A;  2RSE A;  2UZ5 A;  2N87 A;  5DF0 A;  1U79 A;  3CHE A;  3RGC A;  2PPP A;  1W1P A;  1Q6U A;  3AS0 A;  1E6P A;  4MPK A;  2XPA A;  3O5Q A;  1EDQ A;  3IKD A;  4TX0 A;  3RM4 A;  1HJX A;  3WD1 A;  1K9T A;  4IT4 A;  4DZ2 A;  2P4V A;  4MTV A;  4NSB A;  5B8I C;  3ARU A;  1E9L A;  1D2K A;  4N19 A;  1ZL1 A;  2D9F A;  4C02 B;  1EHN A;  3IKG A;  2KR7 A;  3CGM A;  3AS1 A;  1HKI A;  4KQZ A;  3LUO A;  1NMV A;  3CHF A;  3KAH A;  1E15 A;  1GRJ A;  4TW8 A;  4P8W A;  3GTY X;  1WAW A;  5HKG A;  4DRH A;  1WNO A;  4AY1 A;  4TNS A;  2IUZ A;  1KFW A;  4ZPW R; 
#chains in the Genus database with same CATH homology
 3WKZ A;  1JNE A;  2L2S A;  3O5F A;  1FFQ A;  2Q5A A;  1JNS A;  4WKA A;  1XRV A;  2XP5 A;  3O5M A;  1W9P A;  2DSU A;  3QOK A;  2O9O A;  4LAX A;  5HW8 A;  4LGX A;  2FAP A;  1QPL A;  1O6I A;  1OGB A;  3WL1 A;  1GUV A;  4TW7 A;  4DWS C;  4WKH A;  3W4R A;  3PRA A;  3PRD A;  3NRK A;  1W26 A;  2DPE A;  3B9E A;  2ITK A;  2KE0 A;  3JYM A;  3WH0 A;  4S3K A;  1D7J A;  4Q22 A;  4JFL A;  4MGV A;  4R0X A;  5DEZ A;  2A3A A;  2LGO A;  2F4E A;  2RUR A;  1UR8 A;  2PV2 A;  4MNJ A;  3FY1 A;  4FAP A;  5I98 A;  1PIN A;  3NTP A;  1CTN A;  1LL4 A;  3ARV A;  2K8I A;  3KCE A;  3CHC A;  1GOI A;  1Q6H A;  1SYT A;  2RUD A;  2ZQS A;  1FKF A;  4JFJ A;  1FKD A;  3UI4 A;  4IQC A;  4DWS D;  4WK9 A;  1R9H A;  4J4O A;  2YBU A;  1HJV A;  4DRQ A;  4ODQ A;  3GPK A;  1X6N A;  2LJ4 A;  4LAW A;  3O5J A;  4MNK A;  3WQW A;  3ARP A;  1HXV A;  4ODN A;  2KO7 A;  4QIB A;  3AQU A;  1A7X A;  3KAD A;  2XP4 A;  4WKF A;  1D7H A;  5GQB A;  1LL6 A;  1SR0 A;  3RFW A;  3G6M A;  4J4N A;  3TC5 A;  4XAK A;  4U84 A;  5HWB A;  2Y78 A;  2RUC A;  2XP8 A;  3UF8 A;  2M1I A;  3ART A;  3B9A A;  2DG4 A;  4Z2G A;  2ZR4 A;  4BF8 A;  3WD4 A;  4P8X A;  2M2A A;  1EIB A;  2XP9 A;  2ZQT A;  1NWU A;  1OWQ A;  1W1Y A;  3WD3 A;  2OLH A;  4TYO A;  4DRN A;  2LPV A;  3O5K A;  1X6L A;  4WJX A;  1NH6 A;  2DT1 A;  1ITX A;  1RD6 A;  1W9V A;  4DZ3 A;  4Z2L A;  3FXY A;  5HW7 A;  1C9H A;  3O5O A;  5HWC A;  4JFI A;  1YAT A;  2B31 A;  1P5Q A;  5GPG A;  4Z2I A;  3IK8 A;  5J6E A;  3O5I A;  4ITZ A;  1E6N A;  3NI6 A;  5GPR A;  1HKJ A;  4G50 A;  2XPB A;  3ARW A;  5DO2 A;  1M5Y A;  1LG2 A;  2MLZ A;  4P8V A;  5HUA A;  1FKK A;  4W9Q A;  3ARS A;  4HAR A;  1B6C A;  4DT4 A;  1EYM A;  2ZQU A;  4IPX A;  1FKJ A;  2RUQ A;  2KGJ A;  2XP3 A;  3ALF A;  4JYS A;  1ZK6 A;  3RM9 A;  2AWG A;  2FDM A;  2PPN A;  3ARQ A;  1JND A;  2XP6 A;  1L1P A;  1ZBC A;  3OOB A;  2MLX A;  1EQ3 A;  1N1A A;  2G8Z A;  1F40 A;  1ROT A;  4G2P A;  2FKE A;  2DT2 A;  3O5R A;  3KAG A;  1D7I A;  2OFN A;  5HW6 A;  2DT0 A;  4DWS A;  4Z2J A;  3CZ8 A;  5HBF A;  4O2T A;  3I6C A;  5HT1 A;  1J4H A;  3KZ7 A;  4NZC A;  4S3J A;  3TCZ A;  1GPF A;  4W9O A;  2PV3 A;  3KAF A;  4NNR A;  1IX5 A;  2WLZ A;  1FAP A;  2ZR6 A;  1KT1 A;  2YBT A;  1BL4 A;  3WD0 A;  4PTM A;  1H0G A;  4LAV A;  1NWS A;  2VN1 A;  2VCD A;  1Q1C A;  4URI A;  1QPF A;  3IHZ A;  1FKI A;  1Q6I A;  3ODK A;  2DSZ A;  2PI6 A;  2DSW A;  3WQV A;  4DRJ A;  1LQ0 A;  2IF4 A;  4DRK A;  3WIJ A;  4FN2 A;  1FKS A;  4TW6 A;  4MAV A;  3WD2 A;  3FAP A;  1JVW A;  1J4R A;  1FD9 A;  1HJW A;  3ALG A;  1E6Z A;  3MDY B;  4HBE A;  3PR9 A;  3CHD A;  3AS2 A;  4DH0 A;  3ARZ A;  4QZV B;  1NSG A;  1YW5 A;  3O5D A;  4IT6 A;  2WM0 A;  2M08 A;  1D6O A;  1ROU A;  1W1V A;  3ARR A;  4WIW A;  1FJD A;  3EY6 A;  2ZR5 A;  3PRB A;  2ZQV A;  2WK2 A;  4ML4 A;  4KR0 B;  3KAC A;  5HTG A;  1LG1 A;  2ESC A;  3G6L A;  2JZV A;  1H0I A;  1WB0 A;  4ODK A;  3UQI A;  2G41 A;  4ODO A;  1E6R A;  3TDB A;  1NMW A;  1W9U A;  2MPH A;  4JFK A;  1NWT A;  4DRP A;  1TFV A;  1OGG A;  2PV1 A;  1LJY A;  3AS3 A;  2A3B A;  5D75 A;  1ZBW A;  3OA5 A;  3KAI A;  5JH8 A;  4MNM A;  3CH9 A;  2O92 A;  3JXV A;  2KFW A;  4MNL A;  4ODL A;  4ZPT R;  1FKG A;  3JYJ A;  1ZB5 A;  3H9R B;  3KAB A;  1ZCN A;  1HKK A;  5DIU A;  5DIV A;  3UI5 A;  2QF8 A;  1FKB A;  1FKT A;  2RQS A;  4ZPV R;  3B7X A;  3UQB A;  3RM8 A;  1J6Y A;  1T11 A;  2AOS A;  1LL7 A;  1ZBV A;  4DWS B;  3CGN A;  2A3C A;  4L72 B;  3B9D A;  3UQA A;  3ARX A;  1Y0O A;  2KI3 A;  5BXJ A;  4ZS6 A;  1BKF A;  4JFM A;  3PA7 A;  1HKM A;  2PBC A;  4ODP A;  2PPO A;  3O5E A;  2DG9 A;  4W5U A;  1FFR A;  3O5L A;  1F8A B;  2F2D A;  3WL0 A;  4R5E A;  1JNT A;  4LAY A;  1TCO C;  2XP7 A;  4MSP A;  1FKL A;  2MNT A;  4DRM A;  4Z2H A;  1VF8 A;  3ARY A;  1KT0 A;  4U86 A;  4W9P A;  3O5G A;  2DG3 A;  2DT3 A;  3ARO A;  4ODR A;  2A3E A;  1ZU8 A;  4GGQ A;  1FKH A;  4QT3 A;  4QT2 A;  1FKR A;  1QZ2 A;  1J4I A;  4Q7N A;  3B8S A;  1ZBK A;  2MF9 A;  4HBO A;  4L3N A;  1W1T A;  3BXW A;  2DSV A;  4Z2K A;  4U85 A;  3UI6 A;  2WLY A;  1XHG A;  4DRO A;  5DIT A;  1NWR A;  3RME A;  1PBK A;  4DRI A;  4P8U A;  2F21 A;  4DIP A;  2MLY A;  4ODM A;  3VAW A;  4IQ2 A;  3O5P A;  4GIV A;  2LKN A;  1UR9 A;  2RSE A;  2UZ5 A;  2N87 A;  5DF0 A;  1U79 A;  3CHE A;  3RGC A;  2PPP A;  1W1P A;  1Q6U A;  3AS0 A;  1E6P A;  4MPK A;  2XPA A;  3O5Q A;  1EDQ A;  3IKD A;  4TX0 A;  3RM4 A;  1HJX A;  3WD1 A;  1K9T A;  4IT4 A;  4DZ2 A;  4MTV A;  4NSB A;  5B8I C;  3ARU A;  1E9L A;  1D2K A;  4N19 A;  1ZL1 A;  2D9F A;  4C02 B;  1EHN A;  3IKG A;  2KR7 A;  3CGM A;  3AS1 A;  1HKI A;  4KQZ A;  1NMV A;  3CHF A;  3LUO A;  3KAH A;  1E15 A;  4TW8 A;  4P8W A;  1WAW A;  5HKG A;  4DRH A;  1WNO A;  4AY1 A;  4TNS A;  2IUZ A;  1KFW A;  4ZPW R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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