4DRPA

Evaluation of synthetic fk506 analogs as ligands for the fk506-binding proteins 51 and 52: complex of fkbp51 with 2-(3-((r)-3-(3,4-dimethoxyphenyl)-1-((s)-1-(2-((1r,2s)-2-ethyl-1-hydroxy-cyclohexyl)-2-oxoacetyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid from cocrystallization
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
128
structure length
128
Chain Sequence
GAPATVTEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52.
pubmed doi rcsb
molecule tags Isomerase
source organism Homo sapiens
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP5
total genus 36
structure length 128
sequence length 128
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2012-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00254 FKBP_C FKBP-type peptidyl-prolyl cis-trans isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.50.40 Alpha Beta Roll Chitinase A; domain 3 Chitinase A; domain 3 4drpA00
1J4HA 1QPLA 2ZQUA 5BXJA 3NTPA 1FKLA 1FKDA 4TX0A 3IHZA 2XP4A 4O2TA 4DZ2A 2RUQA 3O5JA 1T11A 3CGMA 4J4NA 2LKNA 3PRBA 2VN1A 2XP9A 2ZR6A 1L1PA 1Q1CA 3ODKA 3O5IA 1Q6HA 3KAFA 1ROTA 4DZ3A 3KABA 1FKTA 1FKKA 5HW6A 3KACA 1NMVA 4C02B 4BF8A 2Y78A 4DT4A 3JYJA 3IK8A 3O5MA 4QIBA 2RSEA 4W9QA 3RFWA 3RGCA 1NSGA 2MLZA 5HWBA 4IQ2A 3JXVA 3O5GA 3UI4A 2PBCA 5DIVA 3UQIA 5HKGA 2PV2A 4R0XA 4JFIA 5HW7A 4W9OA 4NNRA 2XP5A 4G50A 3KCEA 1KT0A 1ROUA 2F21A 2ZQVA 1J4RA 2KR7A 2MLXA 3KZ7A 2VCDA 3NRKA 4ITZA 3H9RB 5D75A 5HT1A 1BKFA 1FKBA 4ODLA 5DIUA 5HTGA 4JFKA 1FKGA 2KO7A 4JFMA 2PPNA 3UF8A 3UQAA 1FKRA 4DIPA 1Q6UA 1F8AB 1BL4A 1EQ3A 2DG3A 2LPVA 3LUOA 4U85A 4ODRA 2XP7A 1M5YA 2IF4A 4LAWA 2PPOA 3TC5A 5B8IC 2DG9A 3VAWA 1Y0OA 1F40A 3GPKA 2MNTA 4U84A 1YW5A 2DG4A 2PV3A 2XP6A 4TW6A 4ODMA 3MDYB 1JNSA 4ODPA 1D7HA 3O5DA 2MPHA 2XP8A 3OOBA 1J4IA 1FKSA 1Q6IA 1ZCNA 2RUDA 3O5LA 4JFJA 1EYMA 2PV1A 2ZR4A 5HW8A 2KFWA 2XPAA 4J4OA 5HUAA 1B6CA 1PINA 4ODNA 2ZR5A 3O5RA 1JVWA 4LAXA 3TCZA 3WH0A 1N1AA 3IKGA 1FKHA 4N19A 1FKJA 2M1IA 3FAPA 4QT3A 3O5OA 4DROA 2M08A 3PRDA 2F2DA 1P5QA 1J6YA 1YATA 3KADA 2ZQTA 4DH0A 3JYMA 4GGQA 4IPXA 3KAHA 4DRKA 1JNTA 2ITKA 1W26A 2JZVA 1A7XA 4U86A 2KGJA 2L2SA 5DITA 3O5PA 4ODOA 2N87A 4FN2A 1FKFA 1FD9A 1KT1A 4LAVA 5J6EA 1QZ2A 1NMWA 1FKIA 1U79A 2RUCA 4JFLA 3O5EA 3B7XA 1D7IA 4TW8A 5HWCA 3UQBA 1FAPA 4TW7A 2FKEA 5GPGA 2XPBA 4GIVA 4IQCA 2KE0A 2PPPA 2RQSA 4ODKA 3CGNA 2RURA 4FAPA 3O5FA 4DRMA 2UZ5A 4TYOA 2LGOA 3KAGA 3NI6A 4ODQA 3PA7A 2AWGA 3KAIA 4G2PA 4TNSA 3UI5A 1PBKA 4JYSA 1D7JA 1R9HA 4MSPA 2LJ4A 4LAYA 3I6CA 1ZK6A 1D6OA 4W9PA 2D9FA 3UI6A 2F4EA 2MF9A 4QT2A 1HXVA 1TCOC 2OFNA 2Q5AA 3EY6A 1FJDA 4DRNA 2ZQSA 3O5KA 4DRHA 4DRIA 3TDBA 3O5QA 2KI3A 2FAPA 2K8IA 2M2AA 3IKDA 4DRJA 4DRQA 2MLYA 5I98A 4DRPA 1C9HA 4MGVA 2XP3A 1QPFA
chains in the Genus database with same CATH superfamily
1D2KA 3B9DA 1FKDA 1HKIA 4TX0A 3G6LA 2XP4A 1X6LA 3ARUA 5GQBA 4DZ3A 3KAFA 3KABA 1FKKA 2EULA 3KACA 4C02B 1OGBA 5HWBA 1OGGA 3WQWA 3PR9A 3FXYA 5HKGA 1W1VA 3GU0A 2OLHA 4JFIA 4R0XA 4IT4A 2XP5A 2F23A 1KT0A 1XHGA 3B9AA 5HT1A 3H9RB 5D75A 5DF0A 5HTGA 1ZBVA 4JFKA 1FKGA 2PPNA 4Q7NA 2DG3A 3LUOA 1NWTA 2IF4A 4LAWA 5B8IC 4MTVA 1ZBKA 3VAWA 1H0IA 4Z2KA 1YW5A 2DG4A 2B31A 4TW6A 4ODPA 4JFJA 1FKSA 4AY1A 3O5LA 1ZCNA 3ARTA 2XPAA 1W9VA 4J4OA 5HW8A 2ZR5A 1N1AA 3IKGA 4HBEA 4ZPTR 2O92A 3KADA 5GPRA 4IPXA 2G8ZA 2ESCA 4Z2IA 4U86A 5DITA 2N87A 1JNEA 1NWSA 1OWQA 4TW8A 3ARYA 5GPGA 1HKMA 4IQCA 3WD2A 3ARXA 2RQSA 1LJYA 3KAIA 2WM0A 4MSPA 4LAYA 1LG1A 2Q5AA 2OFNA 3AS3A 3EY6A 1ITXA 4NZCA 5DO2A 1ZB5A 1W1TA 1WB0A 3TDBA 4MNMA 3IKDA 4DRQA 2MLYA 1K9TA 4MGVA 2DT3A 2YBTA 1QPLA 2ZQUA 3O5JA 1T11A 3CGMA 2ZR6A 1WAWA 3AROA 4DWSA 3CH9A 1Q6HA 1ROTA 2YBUA 3AS1A 4HBOA 2Y78A 4ZS6A 4DT4A 3IK8A 4QIBA 1LQ0A 2MLZA 4MNLA 3O5GA 1ZU8A 3UQIA 4ZPVR 2A3CA 5HW7A 4NNRA 4P8WA 4G50A 4WK9A 2ZQVA 1ZBCA 3NRKA 4Z2JA 3KZ7A 2VCDA 2DSVA 1FKBA 3AQUA 1FKRA 4P8XA 2XP7A 1M5YA 2PPOA 1HJVA 4U84A 3EIPA 1GPFA 2PV3A 2PI6A 2XP6A 1JNDA 4ODMA 3MDYB 4P8VA 3O5DA 2MPHA 2XP8A 1J4IA 5HBFA 1EYMA 2PV1A 2ZR4A 3CZ8A 2WLYA 1GUVA 2G41A 4UDMA 1PINA 3BMBA 1JVWA 3TCZA 1FKHA 4N19A 3FAPA 3WD3A 1WNOA 4IT6A 1LL7A 3PRDA 2F2DA 1P5QA 2ZQTA 2WK2A 3JYMA 4GGQA 3KAHA 4WIWA 1JNTA 1W26A 2KGJA 2L2SA 4ODOA 4LAVA 4LGXA 3RM9A 1U79A 3UQBA 1D7IA 4TW7A 3CHFA 1IX5A 4XAKA 2PPPA 3WQVA 1TFVA 4Z2LA 3O5FA 4DRMA 3WKZA 3AS0A 5DEZA 1E6RA 1LG2A 1H0GA 3NI6A 4ODQA 4G2PA 3UI5A 1RD6A 2DSWA 2PN0A 1ZK6A 4W9PA 2F4EA 1TCOC 1FJDA 2FDMA 2ZQSA 1E6PA 4DRIA 3ARSA 2KI3A 2K8IA 4HARA 1GOIA 1J4HA 1JCHB 4Z2GA 3WD1A 4DWSC 3NTPA 5BXJA 1FFQA 3IHZA 4O2TA 4J4NA 2LKNA 3PRBA 2XP9A 1Q1CA 3ODKA 3FY1A 3W4RA 5HW6A 1GRJA 4Z2HA 1UR8A 4DWSD 4BF8A 3O5MA 4W9QA 3RFWA 2RSEA 3RGCA 1NSGA 3PRAA 4IQ2A 1FFRA 3JXVA 3UI4A 5DIVA 4PTMA 4S3JA 1SR0A 1ROUA 2F21A 1J4RA 2KR7A 5DIUA 4ODLA 2KO7A 4JFMA 3ARVA 1Q6UA 1F8AB 1LL4A 1NWUA 3ARPA 1NH6A 4DWSB 3QOKA 2LPVA 3OA5A 4U85A 3CHCA 1Y0OA 1F40A 4WKHA 1E44A 3RMEA 3RM4A 1JNSA 2DT0A 1EIBA 1W9UA 2O9OA 3OOBA 4NSBA 4Q22A 3AS2A 2KFWA 5HUAA 1B6CA 4ODNA 3O5RA 1E9LA 1NWRA 2DT1A 3ARZA 4S3KA 3ARWA 1YATA 3ARRA 4DRKA 1W9PA 1FD9A 1KT1A 5J6EA 2RUCA 4JFLA 1UR9A 3B7XA 4URIA 1FAPA 1XRVA 2XPBA 2KE0A 4FAPA 2UZ5A 4MNKA 4TYOA 4MAVA 3KAGA 3PA7A 4JYSA 1D7JA 1VF8A 1R9HA 2LJ4A 3I6CA 1D6OA 1HKJA 2D9FA 3UI6A 2A3AA 4QT2A 2ETNA 2DSZA 2DPEA 2P4VA 2DSUA 1E6ZA 4DRHA 4P8UA 3O5QA 1HJWA 2M2AA 5I98A 1HXVA 4QZVB 1FKLA 4DZ2A 2RUQA 2VN1A 1L1PA 3O5IA 4ML4A 1FKTA 1LL6A 3WD0A 1NMVA 1E15A 2A3BA 3BXWA 3JYJA 2DT2A 2PBCA 3B9EA 1ZL1A 4MPKA 2PV2A 4W9OA 5JH8A 3B8SA 3KCEA 1SYTA 2AOSA 3ALFA 2MLXA 4ITZA 1BKFA 1E6NA 3UQAA 3UF8A 4DIPA 4WKAA 1BL4A 1EQ3A 3RM8A 4W5UA 4ODRA 3WL0A 3TC5A 2DG9A 3GPKA 2MNTA 2QF8A 4ZPWR 1HJXA 2IUZA 1D7HA 2RUDA 1Q6IA 3WD4A 4KR0B 4L72B 4DROA 4LAXA 3WH0A 1FKJA 2M1IA 4KQZA 3O5OA 4QT3A 2M08A 4WJXA 1W1PA 1J6YA 3WL1A 4DH0A 2ITKA 2JZVA 1A7XA 3O5PA 1O6IA 1W1YA 1FKFA 1EHNA 4FN2A 1QZ2A 1NMWA 1FKIA 3O5EA 5HWCA 3CHEA 2FKEA 3CHDA 4GIVA 2B5UB 4ODKA 3CGNA 2RURA 1KFWA 4R5EA 2LGOA 4MNJA 1X6NA 2AWGA 1EDQA 4TNSA 1PBKA 3GTYX 2A3EA 4WKFA 3G6MA 4L3NA 2MF9A 1HKKA 4DRNA 2WLZA 3O5KA 3ALGA 3WIJA 1CTNA 2FAPA 1ZBWA 3ARQA 4DRJA 4DRPA 1C9HA 2XP3A 1QPFA
chains in the Genus database with same CATH topology
1D2KA 3B9DA 1FKDA 1HKIA 4TX0A 3G6LA 2XP4A 1X6LA 3ARUA 5GQBA 4DZ3A 3KAFA 3KABA 1FKKA 3KACA 4C02B 1OGBA 5HWBA 1OGGA 3WQWA 3PR9A 3FXYA 5HKGA 1W1VA 2OLHA 4JFIA 4R0XA 4IT4A 2XP5A 1KT0A 1XHGA 3B9AA 5HT1A 3H9RB 5D75A 5DF0A 5HTGA 1ZBVA 4JFKA 1FKGA 2PPNA 4Q7NA 2DG3A 3LUOA 1NWTA 2IF4A 4LAWA 5B8IC 4MTVA 1ZBKA 3VAWA 1H0IA 4Z2KA 1YW5A 2DG4A 2B31A 4TW6A 4ODPA 4JFJA 1FKSA 4AY1A 3O5LA 1ZCNA 3ARTA 2XPAA 1W9VA 4J4OA 5HW8A 2ZR5A 1N1AA 3IKGA 4HBEA 4ZPTR 2O92A 3KADA 5GPRA 4IPXA 2G8ZA 2ESCA 4Z2IA 4U86A 5DITA 2N87A 1JNEA 1NWSA 1OWQA 4TW8A 3ARYA 5GPGA 1HKMA 4IQCA 3WD2A 3ARXA 2RQSA 1LJYA 3KAIA 2WM0A 4MSPA 4LAYA 1LG1A 2Q5AA 2OFNA 3AS3A 3EY6A 1ITXA 4NZCA 5DO2A 1ZB5A 1W1TA 1WB0A 3TDBA 4MNMA 3IKDA 4DRQA 2MLYA 1K9TA 4MGVA 2DT3A 2YBTA 1QPLA 2ZQUA 3O5JA 1T11A 3CGMA 2ZR6A 1WAWA 3AROA 4DWSA 3CH9A 1Q6HA 1ROTA 2YBUA 3AS1A 4HBOA 2Y78A 4ZS6A 4DT4A 3IK8A 4QIBA 1LQ0A 2MLZA 4MNLA 3O5GA 1ZU8A 3UQIA 4ZPVR 2A3CA 5HW7A 4NNRA 4P8WA 4G50A 4WK9A 2ZQVA 1ZBCA 3NRKA 4Z2JA 3KZ7A 2VCDA 2DSVA 1FKBA 3AQUA 1FKRA 4P8XA 2XP7A 1M5YA 2PPOA 1HJVA 4U84A 1GPFA 2PV3A 2PI6A 2XP6A 1JNDA 4ODMA 3MDYB 4P8VA 3O5DA 2MPHA 2XP8A 1J4IA 5HBFA 1EYMA 2PV1A 2ZR4A 3CZ8A 2WLYA 1GUVA 2G41A 1PINA 1JVWA 3TCZA 1FKHA 4N19A 3FAPA 3WD3A 1WNOA 4IT6A 1LL7A 3PRDA 2F2DA 1P5QA 2ZQTA 2WK2A 3JYMA 4GGQA 3KAHA 4WIWA 1JNTA 1W26A 2KGJA 2L2SA 4ODOA 4LAVA 4LGXA 3RM9A 1U79A 3UQBA 1D7IA 4TW7A 3CHFA 1IX5A 4XAKA 2PPPA 3WQVA 1TFVA 4Z2LA 3O5FA 4DRMA 3WKZA 3AS0A 5DEZA 1E6RA 1LG2A 1H0GA 3NI6A 4ODQA 4G2PA 3UI5A 1RD6A 2DSWA 1ZK6A 4W9PA 2F4EA 1TCOC 1FJDA 2FDMA 2ZQSA 1E6PA 4DRIA 3ARSA 2KI3A 2K8IA 4HARA 1GOIA 1J4HA 4Z2GA 3WD1A 4DWSC 3NTPA 5BXJA 1FFQA 3IHZA 4O2TA 4J4NA 2LKNA 3PRBA 2XP9A 1Q1CA 3ODKA 3FY1A 3W4RA 5HW6A 4Z2HA 1UR8A 4DWSD 4BF8A 3O5MA 4W9QA 3RFWA 2RSEA 3RGCA 1NSGA 3PRAA 4IQ2A 1FFRA 3JXVA 3UI4A 5DIVA 4PTMA 4S3JA 1SR0A 1ROUA 2F21A 1J4RA 2KR7A 5DIUA 4ODLA 2KO7A 4JFMA 3ARVA 1Q6UA 1F8AB 1LL4A 1NWUA 3ARPA 1NH6A 4DWSB 3QOKA 2LPVA 3OA5A 4U85A 3CHCA 1Y0OA 1F40A 4WKHA 3RMEA 3RM4A 1JNSA 2DT0A 1EIBA 1W9UA 2O9OA 3OOBA 4NSBA 4Q22A 3AS2A 2KFWA 5HUAA 1B6CA 4ODNA 3O5RA 1E9LA 1NWRA 2DT1A 3ARZA 4S3KA 3ARWA 1YATA 3ARRA 4DRKA 1W9PA 1FD9A 1KT1A 5J6EA 2RUCA 4JFLA 1UR9A 3B7XA 4URIA 1FAPA 1XRVA 2XPBA 2KE0A 4FAPA 2UZ5A 4MNKA 4TYOA 4MAVA 3KAGA 3PA7A 4JYSA 1D7JA 1VF8A 1R9HA 2LJ4A 3I6CA 1D6OA 1HKJA 2D9FA 3UI6A 2A3AA 4QT2A 2DSZA 2DPEA 2DSUA 1E6ZA 4DRHA 4P8UA 3O5QA 1HJWA 2M2AA 5I98A 1HXVA 4QZVB 1FKLA 4DZ2A 2RUQA 2VN1A 1L1PA 3O5IA 4ML4A 1FKTA 1LL6A 3WD0A 1NMVA 1E15A 2A3BA 3BXWA 3JYJA 2DT2A 2PBCA 3B9EA 1ZL1A 4MPKA 2PV2A 4W9OA 5JH8A 3B8SA 3KCEA 1SYTA 2AOSA 3ALFA 2MLXA 4ITZA 1BKFA 1E6NA 3UQAA 3UF8A 4DIPA 4WKAA 1BL4A 1EQ3A 3RM8A 4W5UA 4ODRA 3WL0A 3TC5A 2DG9A 3GPKA 2MNTA 2QF8A 4ZPWR 1HJXA 2IUZA 1D7HA 2RUDA 1Q6IA 3WD4A 4KR0B 4L72B 4DROA 4LAXA 3WH0A 1FKJA 2M1IA 4KQZA 3O5OA 4QT3A 2M08A 4WJXA 1W1PA 1J6YA 3WL1A 4DH0A 2ITKA 2JZVA 1A7XA 3O5PA 1O6IA 1W1YA 1FKFA 1EHNA 4FN2A 1QZ2A 1NMWA 1FKIA 3O5EA 5HWCA 3CHEA 2FKEA 3CHDA 4GIVA 4ODKA 3CGNA 2RURA 1KFWA 4R5EA 2LGOA 4MNJA 1X6NA 2AWGA 1EDQA 4TNSA 1PBKA 2A3EA 4WKFA 3G6MA 4L3NA 2MF9A 1HKKA 4DRNA 2WLZA 3O5KA 3ALGA 3WIJA 1CTNA 2FAPA 1ZBWA 3ARQA 4DRJA 4DRPA 1C9HA 2XP3A 1QPFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1J4H A;  1QPL A;  2ZQU A;  5BXJ A;  3NTP A;  1FKL A;  1FKD A;  4TX0 A;  3IHZ A;  2XP4 A;  4O2T A;  4DZ2 A;  2RUQ A;  3O5J A;  1T11 A;  3CGM A;  4J4N A;  2LKN A;  3PRB A;  2VN1 A;  2XP9 A;  2ZR6 A;  1L1P A;  1Q1C A;  3ODK A;  3O5I A;  1Q6H A;  3KAF A;  1ROT A;  4DZ3 A;  3KAB A;  1FKT A;  1FKK A;  5HW6 A;  3KAC A;  1NMV A;  4C02 B;  4BF8 A;  2Y78 A;  4DT4 A;  3JYJ A;  3IK8 A;  3O5M A;  4QIB A;  2RSE A;  4W9Q A;  3RFW A;  3RGC A;  1NSG A;  2MLZ A;  5HWB A;  4IQ2 A;  3JXV A;  3O5G A;  3UI4 A;  2PBC A;  5DIV A;  3UQI A;  5HKG A;  2PV2 A;  4R0X A;  4JFI A;  5HW7 A;  4W9O A;  4NNR A;  2XP5 A;  4G50 A;  3KCE A;  1KT0 A;  1ROU A;  2F21 A;  2ZQV A;  1J4R A;  2KR7 A;  2MLX A;  3KZ7 A;  2VCD A;  3NRK A;  4ITZ A;  3H9R B;  5D75 A;  5HT1 A;  1BKF A;  1FKB A;  4ODL A;  5DIU A;  5HTG A;  4JFK A;  1FKG A;  2KO7 A;  4JFM A;  2PPN A;  3UF8 A;  3UQA A;  1FKR A;  4DIP A;  1Q6U A;  1F8A B;  1BL4 A;  1EQ3 A;  2DG3 A;  2LPV A;  3LUO A;  4U85 A;  4ODR A;  2XP7 A;  1M5Y A;  2IF4 A;  4LAW A;  2PPO A;  3TC5 A;  5B8I C;  2DG9 A;  3VAW A;  1Y0O A;  1F40 A;  3GPK A;  2MNT A;  4U84 A;  1YW5 A;  2DG4 A;  2PV3 A;  2XP6 A;  4TW6 A;  4ODM A;  3MDY B;  1JNS A;  4ODP A;  1D7H A;  3O5D A;  2MPH A;  2XP8 A;  3OOB A;  1J4I A;  1FKS A;  1Q6I A;  1ZCN A;  2RUD A;  3O5L A;  4JFJ A;  1EYM A;  2PV1 A;  2ZR4 A;  5HW8 A;  2KFW A;  2XPA A;  4J4O A;  5HUA A;  1B6C A;  1PIN A;  4ODN A;  2ZR5 A;  3O5R A;  1JVW A;  4LAX A;  3TCZ A;  3WH0 A;  1N1A A;  3IKG A;  1FKH A;  4N19 A;  1FKJ A;  2M1I A;  3FAP A;  4QT3 A;  3O5O A;  4DRO A;  2M08 A;  3PRD A;  2F2D A;  1P5Q A;  1J6Y A;  1YAT A;  3KAD A;  2ZQT A;  4DH0 A;  3JYM A;  4GGQ A;  4IPX A;  3KAH A;  4DRK A;  1JNT A;  2ITK A;  1W26 A;  2JZV A;  1A7X A;  4U86 A;  2KGJ A;  2L2S A;  5DIT A;  3O5P A;  4ODO A;  2N87 A;  4FN2 A;  1FKF A;  1FD9 A;  1KT1 A;  4LAV A;  5J6E A;  1QZ2 A;  1NMW A;  1FKI A;  1U79 A;  2RUC A;  4JFL A;  3O5E A;  3B7X A;  1D7I A;  4TW8 A;  5HWC A;  3UQB A;  1FAP A;  4TW7 A;  2FKE A;  5GPG A;  2XPB A;  4GIV A;  4IQC A;  2KE0 A;  2PPP A;  2RQS A;  4ODK A;  3CGN A;  2RUR A;  4FAP A;  3O5F A;  4DRM A;  2UZ5 A;  4TYO A;  2LGO A;  3KAG A;  3NI6 A;  4ODQ A;  3PA7 A;  2AWG A;  3KAI A;  4G2P A;  4TNS A;  3UI5 A;  1PBK A;  4JYS A;  1D7J A;  1R9H A;  4MSP A;  2LJ4 A;  4LAY A;  3I6C A;  1ZK6 A;  1D6O A;  4W9P A;  2D9F A;  3UI6 A;  2F4E A;  2MF9 A;  4QT2 A;  1HXV A;  1TCO C;  2OFN A;  2Q5A A;  3EY6 A;  1FJD A;  4DRN A;  2ZQS A;  3O5K A;  4DRH A;  4DRI A;  3TDB A;  3O5Q A;  2KI3 A;  2FAP A;  2K8I A;  2M2A A;  3IKD A;  4DRJ A;  4DRQ A;  2MLY A;  5I98 A;  4DRP A;  1C9H A;  4MGV A;  2XP3 A;  1QPF A; 
#chains in the Genus database with same CATH topology
 1D2K A;  3B9D A;  1FKD A;  1HKI A;  4TX0 A;  3G6L A;  2XP4 A;  1X6L A;  3ARU A;  5GQB A;  4DZ3 A;  3KAF A;  3KAB A;  1FKK A;  2EUL A;  3KAC A;  4C02 B;  1OGB A;  5HWB A;  1OGG A;  3WQW A;  3PR9 A;  3FXY A;  5HKG A;  1W1V A;  3GU0 A;  2OLH A;  4JFI A;  4R0X A;  4IT4 A;  2XP5 A;  2F23 A;  1KT0 A;  1XHG A;  3B9A A;  5HT1 A;  3H9R B;  5D75 A;  5DF0 A;  5HTG A;  1ZBV A;  4JFK A;  1FKG A;  2PPN A;  4Q7N A;  2DG3 A;  3LUO A;  1NWT A;  2IF4 A;  4LAW A;  5B8I C;  4MTV A;  1ZBK A;  3VAW A;  1H0I A;  4Z2K A;  1YW5 A;  2DG4 A;  2B31 A;  4TW6 A;  4ODP A;  4JFJ A;  1FKS A;  4AY1 A;  3O5L A;  1ZCN A;  3ART A;  2XPA A;  1W9V A;  4J4O A;  5HW8 A;  2ZR5 A;  1N1A A;  3IKG A;  4HBE A;  4ZPT R;  2O92 A;  3KAD A;  5GPR A;  4IPX A;  2G8Z A;  2ESC A;  4Z2I A;  4U86 A;  5DIT A;  2N87 A;  1JNE A;  1NWS A;  1OWQ A;  4TW8 A;  3ARY A;  5GPG A;  1HKM A;  4IQC A;  3WD2 A;  3ARX A;  2RQS A;  1LJY A;  3KAI A;  2WM0 A;  4MSP A;  4LAY A;  1LG1 A;  2Q5A A;  2OFN A;  3AS3 A;  3EY6 A;  1ITX A;  4NZC A;  5DO2 A;  1ZB5 A;  1W1T A;  1WB0 A;  3TDB A;  4MNM A;  3IKD A;  4DRQ A;  2MLY A;  1K9T A;  4MGV A;  2DT3 A;  2YBT A;  1QPL A;  2ZQU A;  3O5J A;  1T11 A;  3CGM A;  2ZR6 A;  1WAW A;  3ARO A;  4DWS A;  3CH9 A;  1Q6H A;  1ROT A;  2YBU A;  3AS1 A;  4HBO A;  2Y78 A;  4ZS6 A;  4DT4 A;  3IK8 A;  4QIB A;  1LQ0 A;  2MLZ A;  4MNL A;  3O5G A;  1ZU8 A;  3UQI A;  4ZPV R;  2A3C A;  5HW7 A;  4NNR A;  4P8W A;  4G50 A;  4WK9 A;  2ZQV A;  1ZBC A;  3NRK A;  4Z2J A;  3KZ7 A;  2VCD A;  2DSV A;  1FKB A;  3AQU A;  1FKR A;  4P8X A;  2XP7 A;  1M5Y A;  2PPO A;  1HJV A;  4U84 A;  3EIP A;  1GPF A;  2PV3 A;  2PI6 A;  2XP6 A;  1JND A;  4ODM A;  3MDY B;  4P8V A;  3O5D A;  2MPH A;  2XP8 A;  1J4I A;  5HBF A;  1EYM A;  2PV1 A;  2ZR4 A;  3CZ8 A;  2WLY A;  1GUV A;  2G41 A;  4UDM A;  1PIN A;  3BMB A;  1JVW A;  3TCZ A;  1FKH A;  4N19 A;  3FAP A;  3WD3 A;  1WNO A;  4IT6 A;  1LL7 A;  3PRD A;  2F2D A;  1P5Q A;  2ZQT A;  2WK2 A;  3JYM A;  4GGQ A;  3KAH A;  4WIW A;  1JNT A;  1W26 A;  2KGJ A;  2L2S A;  4ODO A;  4LAV A;  4LGX A;  3RM9 A;  1U79 A;  3UQB A;  1D7I A;  4TW7 A;  3CHF A;  1IX5 A;  4XAK A;  2PPP A;  3WQV A;  1TFV A;  4Z2L A;  3O5F A;  4DRM A;  3WKZ A;  3AS0 A;  5DEZ A;  1E6R A;  1LG2 A;  1H0G A;  3NI6 A;  4ODQ A;  4G2P A;  3UI5 A;  1RD6 A;  2DSW A;  2PN0 A;  1ZK6 A;  4W9P A;  2F4E A;  1TCO C;  1FJD A;  2FDM A;  2ZQS A;  1E6P A;  4DRI A;  3ARS A;  2KI3 A;  2K8I A;  4HAR A;  1GOI A;  1J4H A;  1JCH B;  4Z2G A;  3WD1 A;  4DWS C;  3NTP A;  5BXJ A;  1FFQ A;  3IHZ A;  4O2T A;  4J4N A;  2LKN A;  3PRB A;  2XP9 A;  1Q1C A;  3ODK A;  3FY1 A;  3W4R A;  5HW6 A;  1GRJ A;  4Z2H A;  1UR8 A;  4DWS D;  4BF8 A;  3O5M A;  4W9Q A;  3RFW A;  2RSE A;  3RGC A;  1NSG A;  3PRA A;  4IQ2 A;  1FFR A;  3JXV A;  3UI4 A;  5DIV A;  4PTM A;  4S3J A;  1SR0 A;  1ROU A;  2F21 A;  1J4R A;  2KR7 A;  5DIU A;  4ODL A;  2KO7 A;  4JFM A;  3ARV A;  1Q6U A;  1F8A B;  1LL4 A;  1NWU A;  3ARP A;  1NH6 A;  4DWS B;  3QOK A;  2LPV A;  3OA5 A;  4U85 A;  3CHC A;  1Y0O A;  1F40 A;  4WKH A;  1E44 A;  3RME A;  3RM4 A;  1JNS A;  2DT0 A;  1EIB A;  1W9U A;  2O9O A;  3OOB A;  4NSB A;  4Q22 A;  3AS2 A;  2KFW A;  5HUA A;  1B6C A;  4ODN A;  3O5R A;  1E9L A;  1NWR A;  2DT1 A;  3ARZ A;  4S3K A;  3ARW A;  1YAT A;  3ARR A;  4DRK A;  1W9P A;  1FD9 A;  1KT1 A;  5J6E A;  2RUC A;  4JFL A;  1UR9 A;  3B7X A;  4URI A;  1FAP A;  1XRV A;  2XPB A;  2KE0 A;  4FAP A;  2UZ5 A;  4MNK A;  4TYO A;  4MAV A;  3KAG A;  3PA7 A;  4JYS A;  1D7J A;  1VF8 A;  1R9H A;  2LJ4 A;  3I6C A;  1D6O A;  1HKJ A;  2D9F A;  3UI6 A;  2A3A A;  4QT2 A;  2ETN A;  2DSZ A;  2DPE A;  2P4V A;  2DSU A;  1E6Z A;  4DRH A;  4P8U A;  3O5Q A;  1HJW A;  2M2A A;  5I98 A;  1HXV A;  4QZV B;  1FKL A;  4DZ2 A;  2RUQ A;  2VN1 A;  1L1P A;  3O5I A;  4ML4 A;  1FKT A;  1LL6 A;  3WD0 A;  1NMV A;  1E15 A;  2A3B A;  3BXW A;  3JYJ A;  2DT2 A;  2PBC A;  3B9E A;  1ZL1 A;  4MPK A;  2PV2 A;  4W9O A;  5JH8 A;  3B8S A;  3KCE A;  1SYT A;  2AOS A;  3ALF A;  2MLX A;  4ITZ A;  1BKF A;  1E6N A;  3UQA A;  3UF8 A;  4DIP A;  4WKA A;  1BL4 A;  1EQ3 A;  3RM8 A;  4W5U A;  4ODR A;  3WL0 A;  3TC5 A;  2DG9 A;  3GPK A;  2MNT A;  2QF8 A;  4ZPW R;  1HJX A;  2IUZ A;  1D7H A;  2RUD A;  1Q6I A;  3WD4 A;  4KR0 B;  4L72 B;  4DRO A;  4LAX A;  3WH0 A;  1FKJ A;  2M1I A;  4KQZ A;  3O5O A;  4QT3 A;  2M08 A;  4WJX A;  1W1P A;  1J6Y A;  3WL1 A;  4DH0 A;  2ITK A;  2JZV A;  1A7X A;  3O5P A;  1O6I A;  1W1Y A;  1FKF A;  1EHN A;  4FN2 A;  1QZ2 A;  1NMW A;  1FKI A;  3O5E A;  5HWC A;  3CHE A;  2FKE A;  3CHD A;  4GIV A;  2B5U B;  4ODK A;  3CGN A;  2RUR A;  1KFW A;  4R5E A;  2LGO A;  4MNJ A;  1X6N A;  2AWG A;  1EDQ A;  4TNS A;  1PBK A;  3GTY X;  2A3E A;  4WKF A;  3G6M A;  4L3N A;  2MF9 A;  1HKK A;  4DRN A;  2WLZ A;  3O5K A;  3ALG A;  3WIJ A;  1CTN A;  2FAP A;  1ZBW A;  3ARQ A;  4DRJ A;  4DRP A;  1C9H A;  2XP3 A;  1QPF A; 
#chains in the Genus database with same CATH homology
 1D2K A;  3B9D A;  1FKD A;  1HKI A;  4TX0 A;  3G6L A;  2XP4 A;  1X6L A;  3ARU A;  5GQB A;  4DZ3 A;  3KAF A;  3KAB A;  1FKK A;  3KAC A;  4C02 B;  1OGB A;  5HWB A;  1OGG A;  3WQW A;  3PR9 A;  3FXY A;  5HKG A;  1W1V A;  2OLH A;  4JFI A;  4R0X A;  4IT4 A;  2XP5 A;  1KT0 A;  1XHG A;  3B9A A;  5HT1 A;  3H9R B;  5D75 A;  5DF0 A;  5HTG A;  1ZBV A;  4JFK A;  1FKG A;  2PPN A;  4Q7N A;  2DG3 A;  3LUO A;  1NWT A;  2IF4 A;  4LAW A;  5B8I C;  4MTV A;  1ZBK A;  3VAW A;  1H0I A;  4Z2K A;  1YW5 A;  2DG4 A;  2B31 A;  4TW6 A;  4ODP A;  4JFJ A;  1FKS A;  4AY1 A;  3O5L A;  1ZCN A;  3ART A;  2XPA A;  1W9V A;  4J4O A;  5HW8 A;  2ZR5 A;  1N1A A;  3IKG A;  4HBE A;  4ZPT R;  2O92 A;  3KAD A;  5GPR A;  4IPX A;  2G8Z A;  2ESC A;  4Z2I A;  4U86 A;  5DIT A;  2N87 A;  1JNE A;  1NWS A;  1OWQ A;  4TW8 A;  3ARY A;  5GPG A;  1HKM A;  4IQC A;  3WD2 A;  3ARX A;  2RQS A;  1LJY A;  3KAI A;  2WM0 A;  4MSP A;  4LAY A;  1LG1 A;  2Q5A A;  2OFN A;  3AS3 A;  3EY6 A;  1ITX A;  4NZC A;  5DO2 A;  1ZB5 A;  1W1T A;  1WB0 A;  3TDB A;  4MNM A;  3IKD A;  4DRQ A;  2MLY A;  1K9T A;  4MGV A;  2DT3 A;  2YBT A;  1QPL A;  2ZQU A;  3O5J A;  1T11 A;  3CGM A;  2ZR6 A;  1WAW A;  3ARO A;  4DWS A;  3CH9 A;  1Q6H A;  1ROT A;  2YBU A;  3AS1 A;  4HBO A;  2Y78 A;  4ZS6 A;  4DT4 A;  3IK8 A;  4QIB A;  1LQ0 A;  2MLZ A;  4MNL A;  3O5G A;  1ZU8 A;  3UQI A;  4ZPV R;  2A3C A;  5HW7 A;  4NNR A;  4P8W A;  4G50 A;  4WK9 A;  2ZQV A;  1ZBC A;  3NRK A;  4Z2J A;  3KZ7 A;  2VCD A;  2DSV A;  1FKB A;  3AQU A;  1FKR A;  4P8X A;  2XP7 A;  1M5Y A;  2PPO A;  1HJV A;  4U84 A;  1GPF A;  2PV3 A;  2PI6 A;  2XP6 A;  1JND A;  4ODM A;  3MDY B;  4P8V A;  3O5D A;  2MPH A;  2XP8 A;  1J4I A;  5HBF A;  1EYM A;  2PV1 A;  2ZR4 A;  3CZ8 A;  2WLY A;  1GUV A;  2G41 A;  1PIN A;  1JVW A;  3TCZ A;  1FKH A;  4N19 A;  3FAP A;  3WD3 A;  1WNO A;  4IT6 A;  1LL7 A;  3PRD A;  2F2D A;  1P5Q A;  2ZQT A;  2WK2 A;  3JYM A;  4GGQ A;  3KAH A;  4WIW A;  1JNT A;  1W26 A;  2KGJ A;  2L2S A;  4ODO A;  4LAV A;  4LGX A;  3RM9 A;  1U79 A;  3UQB A;  1D7I A;  4TW7 A;  3CHF A;  1IX5 A;  4XAK A;  2PPP A;  3WQV A;  1TFV A;  4Z2L A;  3O5F A;  4DRM A;  3WKZ A;  3AS0 A;  5DEZ A;  1E6R A;  1LG2 A;  1H0G A;  3NI6 A;  4ODQ A;  4G2P A;  3UI5 A;  1RD6 A;  2DSW A;  1ZK6 A;  4W9P A;  2F4E A;  1TCO C;  1FJD A;  2FDM A;  2ZQS A;  1E6P A;  4DRI A;  3ARS A;  2KI3 A;  2K8I A;  4HAR A;  1GOI A;  1J4H A;  4Z2G A;  3WD1 A;  4DWS C;  3NTP A;  5BXJ A;  1FFQ A;  3IHZ A;  4O2T A;  4J4N A;  2LKN A;  3PRB A;  2XP9 A;  1Q1C A;  3ODK A;  3FY1 A;  3W4R A;  5HW6 A;  4Z2H A;  1UR8 A;  4DWS D;  4BF8 A;  3O5M A;  4W9Q A;  3RFW A;  2RSE A;  3RGC A;  1NSG A;  3PRA A;  4IQ2 A;  1FFR A;  3JXV A;  3UI4 A;  5DIV A;  4PTM A;  4S3J A;  1SR0 A;  1ROU A;  2F21 A;  1J4R A;  2KR7 A;  5DIU A;  4ODL A;  2KO7 A;  4JFM A;  3ARV A;  1Q6U A;  1F8A B;  1LL4 A;  1NWU A;  3ARP A;  1NH6 A;  4DWS B;  3QOK A;  2LPV A;  3OA5 A;  4U85 A;  3CHC A;  1Y0O A;  1F40 A;  4WKH A;  3RME A;  3RM4 A;  1JNS A;  2DT0 A;  1EIB A;  1W9U A;  2O9O A;  3OOB A;  4NSB A;  4Q22 A;  3AS2 A;  2KFW A;  5HUA A;  1B6C A;  4ODN A;  3O5R A;  1E9L A;  1NWR A;  2DT1 A;  3ARZ A;  4S3K A;  3ARW A;  1YAT A;  3ARR A;  4DRK A;  1W9P A;  1FD9 A;  1KT1 A;  5J6E A;  2RUC A;  4JFL A;  1UR9 A;  3B7X A;  4URI A;  1FAP A;  1XRV A;  2XPB A;  2KE0 A;  4FAP A;  2UZ5 A;  4MNK A;  4TYO A;  4MAV A;  3KAG A;  3PA7 A;  4JYS A;  1D7J A;  1VF8 A;  1R9H A;  2LJ4 A;  3I6C A;  1D6O A;  1HKJ A;  2D9F A;  3UI6 A;  2A3A A;  4QT2 A;  2DSZ A;  2DPE A;  2DSU A;  1E6Z A;  4DRH A;  4P8U A;  3O5Q A;  1HJW A;  2M2A A;  5I98 A;  1HXV A;  4QZV B;  1FKL A;  4DZ2 A;  2RUQ A;  2VN1 A;  1L1P A;  3O5I A;  4ML4 A;  1FKT A;  1LL6 A;  3WD0 A;  1NMV A;  1E15 A;  2A3B A;  3BXW A;  3JYJ A;  2DT2 A;  2PBC A;  3B9E A;  1ZL1 A;  4MPK A;  2PV2 A;  4W9O A;  5JH8 A;  3B8S A;  3KCE A;  1SYT A;  2AOS A;  3ALF A;  2MLX A;  4ITZ A;  1BKF A;  1E6N A;  3UQA A;  3UF8 A;  4DIP A;  4WKA A;  1BL4 A;  1EQ3 A;  3RM8 A;  4W5U A;  4ODR A;  3WL0 A;  3TC5 A;  2DG9 A;  3GPK A;  2MNT A;  2QF8 A;  4ZPW R;  1HJX A;  2IUZ A;  1D7H A;  2RUD A;  1Q6I A;  3WD4 A;  4KR0 B;  4L72 B;  4DRO A;  4LAX A;  3WH0 A;  1FKJ A;  2M1I A;  4KQZ A;  3O5O A;  4QT3 A;  2M08 A;  4WJX A;  1W1P A;  1J6Y A;  3WL1 A;  4DH0 A;  2ITK A;  2JZV A;  1A7X A;  3O5P A;  1O6I A;  1W1Y A;  1FKF A;  1EHN A;  4FN2 A;  1QZ2 A;  1NMW A;  1FKI A;  3O5E A;  5HWC A;  3CHE A;  2FKE A;  3CHD A;  4GIV A;  4ODK A;  3CGN A;  2RUR A;  1KFW A;  4R5E A;  2LGO A;  4MNJ A;  1X6N A;  2AWG A;  1EDQ A;  4TNS A;  1PBK A;  2A3E A;  4WKF A;  3G6M A;  4L3N A;  2MF9 A;  1HKK A;  4DRN A;  2WLZ A;  3O5K A;  3ALG A;  3WIJ A;  1CTN A;  2FAP A;  1ZBW A;  3ARQ A;  4DRJ A;  4DRP A;  1C9H A;  2XP3 A;  1QPF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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