5DIUA

The fk1 domain of fkbp51 in complex with the new synthetic ligand 2-(3-((r)-1-((s)-1-((s)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carboxamido)-3-(3,4-dimethoxyphenyl)propyl)phenoxy)acetic acid
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
128
structure length
128
Chain Sequence
GAPATVTEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51.
pubmed doi rcsb
molecule tags Isomerase
source organism Homo sapiens
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP5
total genus 32
structure length 128
sequence length 128
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2015-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00254 FKBP_C FKBP-type peptidyl-prolyl cis-trans isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.50.40 Alpha Beta Roll Chitinase A; domain 3 Chitinase A; domain 3 5diuA00
4JFIA 3JYMA 2Q5AA 2XP9A 2MLYA 3PA7A 4DRPA 2RUDA 2MNTA 4DRIA 4LAYA 4TYOA 2VCDA 2XPBA 1J4IA 2FKEA 4TW8A 3O5DA 1NMVA 3RGCA 1B6CA 3LUOA 5D75A 1FKBA 2LJ4A 2F4EA 2K8IA 3JYJA 3IHZA 3UI6A 2MF9A 4ODLA 1TCOC 2UZ5A 1FKTA 2LKNA 4W9PA 5HUAA 3NTPA 1D6OA 1NMWA 2KO7A 1KT0A 3NRKA 3KAIA 4FN2A 2KFWA 2RQSA 1FKGA 5HW7A 4BF8A 3UQAA 2JZVA 3UQIA 1QPLA 1YATA 2AWGA 2KE0A 4QIBA 3UI5A 3MDYB 1T11A 4DRKA 1L1PA 2PPNA 3KAHA 2FAPA 1D7HA 1J4HA 2M1IA 2MLZA 5I98A 2XPAA 1FKHA 1FAPA 2Y78A 4GGQA 1Q1CA 5DIUA 5HW8A 2RSEA 5HT1A 3O5QA 3TDBA 2OFNA 3UQBA 2MLXA 2KI3A 1D7JA 2XP3A 4O2TA 4J4OA 3I6CA 4ODRA 1JVWA 5DITA 1QZ2A 4DZ2A 3IK8A 5J6EA 4QT2A 4JFLA 3EY6A 2L2SA 3PRBA 4TNSA 2VN1A 2ZQVA 1BKFA 3UI4A 4DRHA 1ROTA 2DG4A 2PPPA 3KCEA 4MSPA 4DROA 4LAXA 4TW7A 4ODMA 4W9QA 1Y0OA 2ZQSA 3GPKA 2PV1A 2LPVA 3IKGA 2KR7A 3O5GA 4G2PA 1FKRA 1JNSA 1NSGA 2XP4A 3TC5A 5GPGA 3O5RA 1M5YA 4G50A 1PBKA 1ZK6A 3FAPA 5HTGA 1FKSA 1ZCNA 3TCZA 2KGJA 3CGNA 4QT3A 1FKFA 2RURA 2ZQTA 5HKGA 2PPOA 2XP8A 3O5EA 4R0XA 3OOBA 2MPHA 2D9FA 2F21A 3KAGA 4ITZA 1EQ3A 1J6YA 2ZR4A 2ZQUA 3H9RB 4ODKA 1KT1A 1F40A 2DG9A 4GIVA 3O5PA 3WH0A 1U79A 5HW6A 3O5KA 2ZR5A 4U84A 2XP6A 4ODOA 2ITKA 4TW6A 4FAPA 3CGMA 4DH0A 1YW5A 3ODKA 2M08A 3IKDA 3KACA 3VAWA 2ZR6A 1FKLA 1PINA 1Q6HA 1R9HA 4ODNA 1P5QA 2M2AA 4U85A 4IQCA 1EYMA 1J4RA 1F8AB 4U86A 5HWCA 3O5IA 2PV2A 4C02B 1W26A 2RUQA 1JNTA 1Q6UA 3O5JA 4W9OA 1BL4A 1D7IA 1FKDA 4DRMA 1N1AA 1QPFA 5HWBA 2RUCA 2N87A 4JFJA 2PV3A 4N19A 3UF8A 1HXVA 1FKJA 3O5OA 3O5LA 2IF4A 3KADA 3KZ7A 4IPXA 4JFKA 4LAVA 4DRQA 4DRNA 1A7XA 4J4NA 3O5FA 1FKIA 4ODQA 4TX0A 4JFMA 5B8IC 1FJDA 3NI6A 4LAWA 4DIPA 1FKKA 2PBCA 2XP7A 3RFWA 1C9HA 3PRDA 4IQ2A 3JXVA 5DIVA 4JYSA 4NNRA 2DG3A 3O5MA 3B7XA 2XP5A 3KAFA 4DZ3A 5BXJA 1Q6IA 1ROUA 1FD9A 4MGVA 2LGOA 4DRJA 3KABA 2F2DA 4ODPA 4DT4A
chains in the Genus database with same CATH superfamily
2Q5AA 4WK9A 2XP9A 2B5UB 4NSBA 3WD2A 2G41A 1E9LA 3O5DA 3LUOA 1H0GA 1W9VA 4AY1A 2DT0A 4Z2IA 2DSUA 5HUAA 1D6OA 1FKGA 5HW7A 4W5UA 1ZL1A 1NWUA 4QIBA 3MDYB 1HJWA 3B8SA 4IT6A 4DWSD 5HW8A 4GGQA 2RSEA 3TDBA 3ARZA 2MLXA 2KI3A 4O2TA 5J6EA 3AS0A 4QT2A 4XAKA 3EY6A 1FFRA 1JNEA 1K9TA 4Z2LA 1ROTA 2PPPA 3KCEA 2O9OA 4MSPA 4DROA 1NH6A 4TW7A 1IX5A 4ODMA 1Y0OA 3GPKA 4KR0B 2A3EA 1HJXA 4G2PA 1FKRA 1NSGA 1OGGA 2XP4A 1M5YA 1RD6A 4G50A 1HJVA 3ARSA 1PBKA 2EULA 1X6LA 1ZCNA 3WL0A 5HKGA 4P8VA 2XP8A 3O5EA 4R0XA 3ALGA 2MPHA 2F21A 2DT2A 1GOIA 2DSZA 1ZB5A 1F40A 3ARTA 4GIVA 1GRJA 4Z2GA 4UDMA 4Z2JA 2XP6A 4FAPA 4TW6A 3WD0A 3KACA 4MNJA 1FKLA 1P5QA 2M2AA 3CHEA 1EYMA 4U86A 5HWCA 4WKFA 2PV2A 1W1YA 1XRVA 3WD4A 1ZBKA 3AROA 1FFQA 4JFJA 4N19A 1D2KA 3O5LA 2IF4A 4DRNA 4J4NA 3O5FA 1FKIA 2FDMA 4ODQA 1FJDA 3NI6A 1EIBA 2F23A 1OWQA 5JH8A 2WK2A 2DG3A 1EDQA 4WKHA 4MGVA 2LGOA 4NZCA 4DRJA 2F2DA 4ODPA 4P8UA 1J6YA 1W1TA 4DRPA 2MLYA 4WKAA 2DPEA 4TYOA 1E15A 1J4IA 2XPBA 1OGBA 4TW8A 4WIWA 3FXYA 1NWTA 2LJ4A 2F4EA 1WNOA 3UI6A 4FN2A 3KAIA 3FY1A 4R5EA 3RM9A 3UQAA 1YATA 2AWGA 3UI5A 1T11A 1E6RA 5GPRA 1D7HA 4ZPWR 2Y78A 4URIA 3UQBA 1D7JA 4P8WA 1QZ2A 4S3KA 2L2SA 3PRBA 2VN1A 1TFVA 3RM8A 2DT3A 3WL1A 4LAXA 4W9QA 2ZQSA 3O5GA 2LPVA 3IKGA 3WQWA 2YBTA 3CHFA 5GPGA 1UR8A 1CTNA 3PRAA 3TCZA 5HTGA 2KGJA 1FKFA 2RURA 3AS1A 3OA5A 2PPOA 3WD3A 3OOBA 1HKKA 5GQBA 2G8ZA 2DG9A 3WD1A 3WH0A 3B9EA 2AOSA 1WAWA 2DSVA 2ZR5A 2ITKA 1NWRA 1YW5A 3ODKA 2DSWA 3VAWA 3CHDA 2YBUA 1PINA 1Q6HA 4MAVA 3ARYA 4U85A 1W26A 2RUQA 1Q6UA 1EHNA 1LG2A 4DRMA 2A3CA 2PV3A 1LQ0A 3BXWA 3UF8A 1LL7A 4Q7NA 1HXVA 3KADA 1A7XA 4TX0A 4L72B 3RFWA 4IQ2A 1SYTA 3O5MA 5BXJA 2XP5A 3G6LA 1Q6IA 1ROUA 3CZ8A 3KABA 1LL6A 4JFIA 3JYMA 5DO2A 3PA7A 3AQUA 1NMVA 3RGCA 1B6CA 5D75A 3ARUA 2K8IA 3JYJA 3IHZA 1SR0A 4ODLA 4IT4A 2IUZA 3GU0A 4MNKA 3AS2A 1FKTA 4W9PA 4PTMA 3NRKA 1NMWA 2KO7A 2RQSA 4BF8A 4Q22A 2JZVA 3UQIA 1LL4A 1QPLA 2PN0A 4ML4A 4Z2KA 1NWSA 2FAPA 2M1IA 1FAPA 1Q1CA 5DIUA 3O5QA 1X6NA 1XHGA 4ZPTR 4DWSA 1E6ZA 1JVWA 4DZ2A 1UR9A 2ZQVA 1BKFA 2ETNA 4DRHA 2DG4A 4HBOA 4KQZA 3RMEA 2WLZA 2PV1A 1JNSA 2KR7A 3WIJA 1ZU8A 4HBEA 3TC5A 1ITXA 3O5RA 1ZK6A 4L3NA 4MNMA 3FAPA 1W1VA 1W9UA 3CGNA 1W1PA 1ZBCA 3G6MA 4MNLA 3KAGA 4ITZA 4MTVA 3GTYX 3H9RB 4ODKA 3O5PA 1HKJA 5HW6A 3O5KA 4U84A 4ODOA 3B9DA 3CGMA 4DH0A 1E6NA 2M08A 3IKDA 3ARXA 2ZR6A 1R9HA 4ODNA 1J4RA 2WLYA 4C02B 1JNTA 3O5JA 1VF8A 1D7IA 2PI6A 1QPFA 3AS3A 2N87A 4LGXA 3O5OA 4JFKA 2QF8A 4Z2HA 4JFMA 5B8IC 1FKKA 3PRDA 3JXVA 1WB0A 4JYSA 4NNRA 4DZ3A 3KAFA 1FD9A 4MPKA 4DT4A 1HKMA 3ARWA 4HARA 2RUDA 2MNTA 4DRIA 4LAYA 3W4RA 2VCDA 2FKEA 1H0IA 1E6PA 1FKBA 3WQVA 2ESCA 2MF9A 1TCOC 2UZ5A 2LKNA 3CHCA 3NTPA 1KT0A 1JNDA 2KFWA 2KE0A 4DRKA 1L1PA 3ARVA 2PPNA 3KAHA 1J4HA 2MLZA 5I98A 2XPAA 1FKHA 1LG1A 2O92A 2DT1A 5HT1A 2OFNA 1W9PA 2A3BA 2XP3A 4J4OA 4S3JA 3I6CA 4ODRA 5DITA 3IK8A 1HKIA 1ZBVA 4JFLA 2A3AA 4TNSA 1JCHB 3UI4A 5HBFA 3ALFA 4ZS6A 1GUVA 3ARQA 5DF0A 3B9AA 1ZBWA 1FKSA 4QT3A 2ZQTA 4QZVB 3QOKA 2D9FA 2ZR4A 2ZQUA 1KT1A 4DWSC 1U79A 3RM4A 3PR9A 3ARPA 4P8XA 4ZPVR 4IQCA 1O6IA 1F8AB 2P4VA 3O5IA 4WJXA 5DEZA 2WM0A 4W9OA 1BL4A 1FKDA 1N1AA 2B31A 2RUCA 5HWBA 2OLHA 1FKJA 3BMBA 3WKZA 1E44A 3KZ7A 4LAVA 4IPXA 4DRQA 3EIPA 1EQ3A 4DWSB 4DIPA 4LAWA 2PBCA 2XP7A 1C9HA 1LJYA 5DIVA 1GPFA 3B7XA 3CH9A 3ARRA 1KFWA
chains in the Genus database with same CATH topology
2Q5AA 4WK9A 2XP9A 4NSBA 3WD2A 2G41A 1E9LA 3O5DA 3LUOA 1H0GA 1W9VA 4AY1A 2DT0A 4Z2IA 2DSUA 5HUAA 1D6OA 1FKGA 5HW7A 4W5UA 1ZL1A 1NWUA 4QIBA 3MDYB 1HJWA 3B8SA 4IT6A 4DWSD 5HW8A 4GGQA 2RSEA 3TDBA 3ARZA 2MLXA 2KI3A 4O2TA 5J6EA 3AS0A 4QT2A 4XAKA 3EY6A 1FFRA 1JNEA 1K9TA 4Z2LA 1ROTA 2PPPA 3KCEA 2O9OA 4MSPA 4DROA 1NH6A 4TW7A 1IX5A 4ODMA 1Y0OA 3GPKA 4KR0B 2A3EA 1HJXA 4G2PA 1FKRA 1NSGA 1OGGA 2XP4A 1M5YA 1RD6A 4G50A 1HJVA 3ARSA 1PBKA 1X6LA 1ZCNA 3WL0A 5HKGA 4P8VA 2XP8A 3O5EA 4R0XA 3ALGA 2MPHA 2F21A 2DT2A 1GOIA 2DSZA 1ZB5A 1F40A 3ARTA 4GIVA 4Z2GA 4Z2JA 2XP6A 4FAPA 4TW6A 3WD0A 3KACA 4MNJA 1FKLA 1P5QA 2M2AA 3CHEA 1EYMA 4U86A 5HWCA 4WKFA 2PV2A 1W1YA 1XRVA 3WD4A 1ZBKA 3AROA 1FFQA 4JFJA 4N19A 1D2KA 3O5LA 2IF4A 4DRNA 4J4NA 3O5FA 1FKIA 2FDMA 4ODQA 1FJDA 3NI6A 1EIBA 1OWQA 5JH8A 2WK2A 2DG3A 1EDQA 4WKHA 4MGVA 2LGOA 4NZCA 4DRJA 2F2DA 4ODPA 4P8UA 1J6YA 1W1TA 4DRPA 2MLYA 4WKAA 2DPEA 4TYOA 1E15A 1J4IA 2XPBA 1OGBA 4TW8A 4WIWA 3FXYA 1NWTA 2LJ4A 2F4EA 1WNOA 3UI6A 4FN2A 3KAIA 3FY1A 4R5EA 3RM9A 3UQAA 1YATA 2AWGA 3UI5A 1T11A 1E6RA 5GPRA 1D7HA 4ZPWR 2Y78A 4URIA 3UQBA 1D7JA 4P8WA 1QZ2A 4S3KA 2L2SA 3PRBA 2VN1A 1TFVA 3RM8A 2DT3A 3WL1A 4LAXA 4W9QA 2ZQSA 3O5GA 2LPVA 3IKGA 3WQWA 2YBTA 3CHFA 5GPGA 1UR8A 1CTNA 3PRAA 3TCZA 5HTGA 2KGJA 1FKFA 2RURA 3AS1A 3OA5A 2PPOA 3WD3A 3OOBA 1HKKA 5GQBA 2G8ZA 2DG9A 3WD1A 3WH0A 3B9EA 2AOSA 1WAWA 2DSVA 2ZR5A 2ITKA 1NWRA 1YW5A 3ODKA 2DSWA 3VAWA 3CHDA 2YBUA 1PINA 1Q6HA 4MAVA 3ARYA 4U85A 1W26A 2RUQA 1Q6UA 1EHNA 1LG2A 4DRMA 2A3CA 2PV3A 1LQ0A 3BXWA 3UF8A 1LL7A 4Q7NA 1HXVA 3KADA 1A7XA 4TX0A 4L72B 3RFWA 4IQ2A 1SYTA 3O5MA 5BXJA 2XP5A 3G6LA 1Q6IA 1ROUA 3CZ8A 3KABA 1LL6A 4JFIA 3JYMA 5DO2A 3PA7A 3AQUA 1NMVA 3RGCA 1B6CA 5D75A 3ARUA 2K8IA 3JYJA 3IHZA 1SR0A 4ODLA 4IT4A 2IUZA 4MNKA 3AS2A 1FKTA 4W9PA 4PTMA 3NRKA 1NMWA 2KO7A 2RQSA 4BF8A 4Q22A 2JZVA 3UQIA 1LL4A 1QPLA 4ML4A 4Z2KA 1NWSA 2FAPA 2M1IA 1FAPA 1Q1CA 5DIUA 3O5QA 1X6NA 1XHGA 4ZPTR 4DWSA 1E6ZA 1JVWA 4DZ2A 1UR9A 2ZQVA 1BKFA 4DRHA 2DG4A 4HBOA 4KQZA 3RMEA 2WLZA 2PV1A 1JNSA 2KR7A 3WIJA 1ZU8A 4HBEA 3TC5A 1ITXA 3O5RA 1ZK6A 4L3NA 4MNMA 3FAPA 1W1VA 1W9UA 3CGNA 1W1PA 1ZBCA 3G6MA 4MNLA 3KAGA 4ITZA 4MTVA 3H9RB 4ODKA 3O5PA 1HKJA 5HW6A 3O5KA 4U84A 4ODOA 3B9DA 3CGMA 4DH0A 1E6NA 2M08A 3IKDA 3ARXA 2ZR6A 1R9HA 4ODNA 1J4RA 2WLYA 4C02B 1JNTA 3O5JA 1VF8A 1D7IA 2PI6A 1QPFA 3AS3A 2N87A 4LGXA 3O5OA 4JFKA 2QF8A 4Z2HA 4JFMA 5B8IC 1FKKA 3PRDA 3JXVA 1WB0A 4JYSA 4NNRA 4DZ3A 3KAFA 1FD9A 4MPKA 4DT4A 1HKMA 3ARWA 4HARA 2RUDA 2MNTA 4DRIA 4LAYA 3W4RA 2VCDA 2FKEA 1H0IA 1E6PA 1FKBA 3WQVA 2ESCA 2MF9A 1TCOC 2UZ5A 2LKNA 3CHCA 3NTPA 1KT0A 1JNDA 2KFWA 2KE0A 4DRKA 1L1PA 3ARVA 2PPNA 3KAHA 1J4HA 2MLZA 5I98A 2XPAA 1FKHA 1LG1A 2O92A 2DT1A 5HT1A 2OFNA 1W9PA 2A3BA 2XP3A 4J4OA 4S3JA 3I6CA 4ODRA 5DITA 3IK8A 1HKIA 1ZBVA 4JFLA 2A3AA 4TNSA 3UI4A 5HBFA 3ALFA 4ZS6A 1GUVA 3ARQA 5DF0A 3B9AA 1ZBWA 1FKSA 4QT3A 2ZQTA 4QZVB 3QOKA 2D9FA 2ZR4A 2ZQUA 1KT1A 4DWSC 1U79A 3RM4A 3PR9A 3ARPA 4P8XA 4ZPVR 4IQCA 1O6IA 1F8AB 3O5IA 5DEZA 4WJXA 2WM0A 4W9OA 1BL4A 1FKDA 1N1AA 2B31A 2RUCA 5HWBA 2OLHA 1FKJA 3WKZA 3KZ7A 4LAVA 4IPXA 4DRQA 1EQ3A 4DWSB 4DIPA 4LAWA 2PBCA 2XP7A 1C9HA 1LJYA 5DIVA 1GPFA 3B7XA 3CH9A 3ARRA 1KFWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JFI A;  3JYM A;  2Q5A A;  2XP9 A;  2MLY A;  3PA7 A;  4DRP A;  2RUD A;  2MNT A;  4DRI A;  4LAY A;  4TYO A;  2VCD A;  2XPB A;  1J4I A;  2FKE A;  4TW8 A;  3O5D A;  1NMV A;  3RGC A;  1B6C A;  3LUO A;  5D75 A;  1FKB A;  2LJ4 A;  2F4E A;  2K8I A;  3JYJ A;  3IHZ A;  3UI6 A;  2MF9 A;  4ODL A;  1TCO C;  2UZ5 A;  1FKT A;  2LKN A;  4W9P A;  5HUA A;  3NTP A;  1D6O A;  1NMW A;  2KO7 A;  1KT0 A;  3NRK A;  3KAI A;  4FN2 A;  2KFW A;  2RQS A;  1FKG A;  5HW7 A;  4BF8 A;  3UQA A;  2JZV A;  3UQI A;  1QPL A;  1YAT A;  2AWG A;  2KE0 A;  4QIB A;  3UI5 A;  3MDY B;  1T11 A;  4DRK A;  1L1P A;  2PPN A;  3KAH A;  2FAP A;  1D7H A;  1J4H A;  2M1I A;  2MLZ A;  5I98 A;  2XPA A;  1FKH A;  1FAP A;  2Y78 A;  4GGQ A;  1Q1C A;  5DIU A;  5HW8 A;  2RSE A;  5HT1 A;  3O5Q A;  3TDB A;  2OFN A;  3UQB A;  2MLX A;  2KI3 A;  1D7J A;  2XP3 A;  4O2T A;  4J4O A;  3I6C A;  4ODR A;  1JVW A;  5DIT A;  1QZ2 A;  4DZ2 A;  3IK8 A;  5J6E A;  4QT2 A;  4JFL A;  3EY6 A;  2L2S A;  3PRB A;  4TNS A;  2VN1 A;  2ZQV A;  1BKF A;  3UI4 A;  4DRH A;  1ROT A;  2DG4 A;  2PPP A;  3KCE A;  4MSP A;  4DRO A;  4LAX A;  4TW7 A;  4ODM A;  4W9Q A;  1Y0O A;  2ZQS A;  3GPK A;  2PV1 A;  2LPV A;  3IKG A;  2KR7 A;  3O5G A;  4G2P A;  1FKR A;  1JNS A;  1NSG A;  2XP4 A;  3TC5 A;  5GPG A;  3O5R A;  1M5Y A;  4G50 A;  1PBK A;  1ZK6 A;  3FAP A;  5HTG A;  1FKS A;  1ZCN A;  3TCZ A;  2KGJ A;  3CGN A;  4QT3 A;  1FKF A;  2RUR A;  2ZQT A;  5HKG A;  2PPO A;  2XP8 A;  3O5E A;  4R0X A;  3OOB A;  2MPH A;  2D9F A;  2F21 A;  3KAG A;  4ITZ A;  1EQ3 A;  1J6Y A;  2ZR4 A;  2ZQU A;  3H9R B;  4ODK A;  1KT1 A;  1F40 A;  2DG9 A;  4GIV A;  3O5P A;  3WH0 A;  1U79 A;  5HW6 A;  3O5K A;  2ZR5 A;  4U84 A;  2XP6 A;  4ODO A;  2ITK A;  4TW6 A;  4FAP A;  3CGM A;  4DH0 A;  1YW5 A;  3ODK A;  2M08 A;  3IKD A;  3KAC A;  3VAW A;  2ZR6 A;  1FKL A;  1PIN A;  1Q6H A;  1R9H A;  4ODN A;  1P5Q A;  2M2A A;  4U85 A;  4IQC A;  1EYM A;  1J4R A;  1F8A B;  4U86 A;  5HWC A;  3O5I A;  2PV2 A;  4C02 B;  1W26 A;  2RUQ A;  1JNT A;  1Q6U A;  3O5J A;  4W9O A;  1BL4 A;  1D7I A;  1FKD A;  4DRM A;  1N1A A;  1QPF A;  5HWB A;  2RUC A;  2N87 A;  4JFJ A;  2PV3 A;  4N19 A;  3UF8 A;  1HXV A;  1FKJ A;  3O5O A;  3O5L A;  2IF4 A;  3KAD A;  3KZ7 A;  4IPX A;  4JFK A;  4LAV A;  4DRQ A;  4DRN A;  1A7X A;  4J4N A;  3O5F A;  1FKI A;  4ODQ A;  4TX0 A;  4JFM A;  5B8I C;  1FJD A;  3NI6 A;  4LAW A;  4DIP A;  1FKK A;  2PBC A;  2XP7 A;  3RFW A;  1C9H A;  3PRD A;  4IQ2 A;  3JXV A;  5DIV A;  4JYS A;  4NNR A;  2DG3 A;  3O5M A;  3B7X A;  2XP5 A;  3KAF A;  4DZ3 A;  5BXJ A;  1Q6I A;  1ROU A;  1FD9 A;  4MGV A;  2LGO A;  4DRJ A;  3KAB A;  2F2D A;  4ODP A;  4DT4 A; 
#chains in the Genus database with same CATH topology
 2Q5A A;  4WK9 A;  2XP9 A;  2B5U B;  4NSB A;  3WD2 A;  2G41 A;  1E9L A;  3O5D A;  3LUO A;  1H0G A;  1W9V A;  4AY1 A;  2DT0 A;  4Z2I A;  2DSU A;  5HUA A;  1D6O A;  1FKG A;  5HW7 A;  4W5U A;  1ZL1 A;  1NWU A;  4QIB A;  3MDY B;  1HJW A;  3B8S A;  4IT6 A;  4DWS D;  5HW8 A;  4GGQ A;  2RSE A;  3TDB A;  3ARZ A;  2MLX A;  2KI3 A;  4O2T A;  5J6E A;  3AS0 A;  4QT2 A;  4XAK A;  3EY6 A;  1FFR A;  1JNE A;  1K9T A;  4Z2L A;  1ROT A;  2PPP A;  3KCE A;  2O9O A;  4MSP A;  4DRO A;  1NH6 A;  4TW7 A;  1IX5 A;  4ODM A;  1Y0O A;  3GPK A;  4KR0 B;  2A3E A;  1HJX A;  4G2P A;  1FKR A;  1NSG A;  1OGG A;  2XP4 A;  1M5Y A;  1RD6 A;  4G50 A;  1HJV A;  3ARS A;  1PBK A;  2EUL A;  1X6L A;  1ZCN A;  3WL0 A;  5HKG A;  4P8V A;  2XP8 A;  3O5E A;  4R0X A;  3ALG A;  2MPH A;  2F21 A;  2DT2 A;  1GOI A;  2DSZ A;  1ZB5 A;  1F40 A;  3ART A;  4GIV A;  1GRJ A;  4Z2G A;  4UDM A;  4Z2J A;  2XP6 A;  4FAP A;  4TW6 A;  3WD0 A;  3KAC A;  4MNJ A;  1FKL A;  1P5Q A;  2M2A A;  3CHE A;  1EYM A;  4U86 A;  5HWC A;  4WKF A;  2PV2 A;  1W1Y A;  1XRV A;  3WD4 A;  1ZBK A;  3ARO A;  1FFQ A;  4JFJ A;  4N19 A;  1D2K A;  3O5L A;  2IF4 A;  4DRN A;  4J4N A;  3O5F A;  1FKI A;  2FDM A;  4ODQ A;  1FJD A;  3NI6 A;  1EIB A;  2F23 A;  1OWQ A;  5JH8 A;  2WK2 A;  2DG3 A;  1EDQ A;  4WKH A;  4MGV A;  2LGO A;  4NZC A;  4DRJ A;  2F2D A;  4ODP A;  4P8U A;  1J6Y A;  1W1T A;  4DRP A;  2MLY A;  4WKA A;  2DPE A;  4TYO A;  1E15 A;  1J4I A;  2XPB A;  1OGB A;  4TW8 A;  4WIW A;  3FXY A;  1NWT A;  2LJ4 A;  2F4E A;  1WNO A;  3UI6 A;  4FN2 A;  3KAI A;  3FY1 A;  4R5E A;  3RM9 A;  3UQA A;  1YAT A;  2AWG A;  3UI5 A;  1T11 A;  1E6R A;  5GPR A;  1D7H A;  4ZPW R;  2Y78 A;  4URI A;  3UQB A;  1D7J A;  4P8W A;  1QZ2 A;  4S3K A;  2L2S A;  3PRB A;  2VN1 A;  1TFV A;  3RM8 A;  2DT3 A;  3WL1 A;  4LAX A;  4W9Q A;  2ZQS A;  3O5G A;  2LPV A;  3IKG A;  3WQW A;  2YBT A;  3CHF A;  5GPG A;  1UR8 A;  1CTN A;  3PRA A;  3TCZ A;  5HTG A;  2KGJ A;  1FKF A;  2RUR A;  3AS1 A;  3OA5 A;  2PPO A;  3WD3 A;  3OOB A;  1HKK A;  5GQB A;  2G8Z A;  2DG9 A;  3WD1 A;  3WH0 A;  3B9E A;  2AOS A;  1WAW A;  2DSV A;  2ZR5 A;  2ITK A;  1NWR A;  1YW5 A;  3ODK A;  2DSW A;  3VAW A;  3CHD A;  2YBU A;  1PIN A;  1Q6H A;  4MAV A;  3ARY A;  4U85 A;  1W26 A;  2RUQ A;  1Q6U A;  1EHN A;  1LG2 A;  4DRM A;  2A3C A;  2PV3 A;  1LQ0 A;  3BXW A;  3UF8 A;  1LL7 A;  4Q7N A;  1HXV A;  3KAD A;  1A7X A;  4TX0 A;  4L72 B;  3RFW A;  4IQ2 A;  1SYT A;  3O5M A;  5BXJ A;  2XP5 A;  3G6L A;  1Q6I A;  1ROU A;  3CZ8 A;  3KAB A;  1LL6 A;  4JFI A;  3JYM A;  5DO2 A;  3PA7 A;  3AQU A;  1NMV A;  3RGC A;  1B6C A;  5D75 A;  3ARU A;  2K8I A;  3JYJ A;  3IHZ A;  1SR0 A;  4ODL A;  4IT4 A;  2IUZ A;  3GU0 A;  4MNK A;  3AS2 A;  1FKT A;  4W9P A;  4PTM A;  3NRK A;  1NMW A;  2KO7 A;  2RQS A;  4BF8 A;  4Q22 A;  2JZV A;  3UQI A;  1LL4 A;  1QPL A;  2PN0 A;  4ML4 A;  4Z2K A;  1NWS A;  2FAP A;  2M1I A;  1FAP A;  1Q1C A;  5DIU A;  3O5Q A;  1X6N A;  1XHG A;  4ZPT R;  4DWS A;  1E6Z A;  1JVW A;  4DZ2 A;  1UR9 A;  2ZQV A;  1BKF A;  2ETN A;  4DRH A;  2DG4 A;  4HBO A;  4KQZ A;  3RME A;  2WLZ A;  2PV1 A;  1JNS A;  2KR7 A;  3WIJ A;  1ZU8 A;  4HBE A;  3TC5 A;  1ITX A;  3O5R A;  1ZK6 A;  4L3N A;  4MNM A;  3FAP A;  1W1V A;  1W9U A;  3CGN A;  1W1P A;  1ZBC A;  3G6M A;  4MNL A;  3KAG A;  4ITZ A;  4MTV A;  3GTY X;  3H9R B;  4ODK A;  3O5P A;  1HKJ A;  5HW6 A;  3O5K A;  4U84 A;  4ODO A;  3B9D A;  3CGM A;  4DH0 A;  1E6N A;  2M08 A;  3IKD A;  3ARX A;  2ZR6 A;  1R9H A;  4ODN A;  1J4R A;  2WLY A;  4C02 B;  1JNT A;  3O5J A;  1VF8 A;  1D7I A;  2PI6 A;  1QPF A;  3AS3 A;  2N87 A;  4LGX A;  3O5O A;  4JFK A;  2QF8 A;  4Z2H A;  4JFM A;  5B8I C;  1FKK A;  3PRD A;  3JXV A;  1WB0 A;  4JYS A;  4NNR A;  4DZ3 A;  3KAF A;  1FD9 A;  4MPK A;  4DT4 A;  1HKM A;  3ARW A;  4HAR A;  2RUD A;  2MNT A;  4DRI A;  4LAY A;  3W4R A;  2VCD A;  2FKE A;  1H0I A;  1E6P A;  1FKB A;  3WQV A;  2ESC A;  2MF9 A;  1TCO C;  2UZ5 A;  2LKN A;  3CHC A;  3NTP A;  1KT0 A;  1JND A;  2KFW A;  2KE0 A;  4DRK A;  1L1P A;  3ARV A;  2PPN A;  3KAH A;  1J4H A;  2MLZ A;  5I98 A;  2XPA A;  1FKH A;  1LG1 A;  2O92 A;  2DT1 A;  5HT1 A;  2OFN A;  1W9P A;  2A3B A;  2XP3 A;  4J4O A;  4S3J A;  3I6C A;  4ODR A;  5DIT A;  3IK8 A;  1HKI A;  1ZBV A;  4JFL A;  2A3A A;  4TNS A;  1JCH B;  3UI4 A;  5HBF A;  3ALF A;  4ZS6 A;  1GUV A;  3ARQ A;  5DF0 A;  3B9A A;  1ZBW A;  1FKS A;  4QT3 A;  2ZQT A;  4QZV B;  3QOK A;  2D9F A;  2ZR4 A;  2ZQU A;  1KT1 A;  4DWS C;  1U79 A;  3RM4 A;  3PR9 A;  3ARP A;  4P8X A;  4ZPV R;  4IQC A;  1O6I A;  1F8A B;  2P4V A;  3O5I A;  4WJX A;  5DEZ A;  2WM0 A;  4W9O A;  1BL4 A;  1FKD A;  1N1A A;  2B31 A;  2RUC A;  5HWB A;  2OLH A;  1FKJ A;  3BMB A;  3WKZ A;  1E44 A;  3KZ7 A;  4LAV A;  4IPX A;  4DRQ A;  3EIP A;  1EQ3 A;  4DWS B;  4DIP A;  4LAW A;  2PBC A;  2XP7 A;  1C9H A;  1LJY A;  5DIV A;  1GPF A;  3B7X A;  3CH9 A;  3ARR A;  1KFW A; 
#chains in the Genus database with same CATH homology
 2Q5A A;  4WK9 A;  2XP9 A;  4NSB A;  3WD2 A;  2G41 A;  1E9L A;  3O5D A;  3LUO A;  1H0G A;  1W9V A;  4AY1 A;  2DT0 A;  4Z2I A;  2DSU A;  5HUA A;  1D6O A;  1FKG A;  5HW7 A;  4W5U A;  1ZL1 A;  1NWU A;  4QIB A;  3MDY B;  1HJW A;  3B8S A;  4IT6 A;  4DWS D;  5HW8 A;  4GGQ A;  2RSE A;  3TDB A;  3ARZ A;  2MLX A;  2KI3 A;  4O2T A;  5J6E A;  3AS0 A;  4QT2 A;  4XAK A;  3EY6 A;  1FFR A;  1JNE A;  1K9T A;  4Z2L A;  1ROT A;  2PPP A;  3KCE A;  2O9O A;  4MSP A;  4DRO A;  1NH6 A;  4TW7 A;  1IX5 A;  4ODM A;  1Y0O A;  3GPK A;  4KR0 B;  2A3E A;  1HJX A;  4G2P A;  1FKR A;  1NSG A;  1OGG A;  2XP4 A;  1M5Y A;  1RD6 A;  4G50 A;  1HJV A;  3ARS A;  1PBK A;  1X6L A;  1ZCN A;  3WL0 A;  5HKG A;  4P8V A;  2XP8 A;  3O5E A;  4R0X A;  3ALG A;  2MPH A;  2F21 A;  2DT2 A;  1GOI A;  2DSZ A;  1ZB5 A;  1F40 A;  3ART A;  4GIV A;  4Z2G A;  4Z2J A;  2XP6 A;  4FAP A;  4TW6 A;  3WD0 A;  3KAC A;  4MNJ A;  1FKL A;  1P5Q A;  2M2A A;  3CHE A;  1EYM A;  4U86 A;  5HWC A;  4WKF A;  2PV2 A;  1W1Y A;  1XRV A;  3WD4 A;  1ZBK A;  3ARO A;  1FFQ A;  4JFJ A;  4N19 A;  1D2K A;  3O5L A;  2IF4 A;  4DRN A;  4J4N A;  3O5F A;  1FKI A;  2FDM A;  4ODQ A;  1FJD A;  3NI6 A;  1EIB A;  1OWQ A;  5JH8 A;  2WK2 A;  2DG3 A;  1EDQ A;  4WKH A;  4MGV A;  2LGO A;  4NZC A;  4DRJ A;  2F2D A;  4ODP A;  4P8U A;  1J6Y A;  1W1T A;  4DRP A;  2MLY A;  4WKA A;  2DPE A;  4TYO A;  1E15 A;  1J4I A;  2XPB A;  1OGB A;  4TW8 A;  4WIW A;  3FXY A;  1NWT A;  2LJ4 A;  2F4E A;  1WNO A;  3UI6 A;  4FN2 A;  3KAI A;  3FY1 A;  4R5E A;  3RM9 A;  3UQA A;  1YAT A;  2AWG A;  3UI5 A;  1T11 A;  1E6R A;  5GPR A;  1D7H A;  4ZPW R;  2Y78 A;  4URI A;  3UQB A;  1D7J A;  4P8W A;  1QZ2 A;  4S3K A;  2L2S A;  3PRB A;  2VN1 A;  1TFV A;  3RM8 A;  2DT3 A;  3WL1 A;  4LAX A;  4W9Q A;  2ZQS A;  3O5G A;  2LPV A;  3IKG A;  3WQW A;  2YBT A;  3CHF A;  5GPG A;  1UR8 A;  1CTN A;  3PRA A;  3TCZ A;  5HTG A;  2KGJ A;  1FKF A;  2RUR A;  3AS1 A;  3OA5 A;  2PPO A;  3WD3 A;  3OOB A;  1HKK A;  5GQB A;  2G8Z A;  2DG9 A;  3WD1 A;  3WH0 A;  3B9E A;  2AOS A;  1WAW A;  2DSV A;  2ZR5 A;  2ITK A;  1NWR A;  1YW5 A;  3ODK A;  2DSW A;  3VAW A;  3CHD A;  2YBU A;  1PIN A;  1Q6H A;  4MAV A;  3ARY A;  4U85 A;  1W26 A;  2RUQ A;  1Q6U A;  1EHN A;  1LG2 A;  4DRM A;  2A3C A;  2PV3 A;  1LQ0 A;  3BXW A;  3UF8 A;  1LL7 A;  4Q7N A;  1HXV A;  3KAD A;  1A7X A;  4TX0 A;  4L72 B;  3RFW A;  4IQ2 A;  1SYT A;  3O5M A;  5BXJ A;  2XP5 A;  3G6L A;  1Q6I A;  1ROU A;  3CZ8 A;  3KAB A;  1LL6 A;  4JFI A;  3JYM A;  5DO2 A;  3PA7 A;  3AQU A;  1NMV A;  3RGC A;  1B6C A;  5D75 A;  3ARU A;  2K8I A;  3JYJ A;  3IHZ A;  1SR0 A;  4ODL A;  4IT4 A;  2IUZ A;  4MNK A;  3AS2 A;  1FKT A;  4W9P A;  4PTM A;  3NRK A;  1NMW A;  2KO7 A;  2RQS A;  4BF8 A;  4Q22 A;  2JZV A;  3UQI A;  1LL4 A;  1QPL A;  4ML4 A;  4Z2K A;  1NWS A;  2FAP A;  2M1I A;  1FAP A;  1Q1C A;  5DIU A;  3O5Q A;  1X6N A;  1XHG A;  4ZPT R;  4DWS A;  1E6Z A;  1JVW A;  4DZ2 A;  1UR9 A;  2ZQV A;  1BKF A;  4DRH A;  2DG4 A;  4HBO A;  4KQZ A;  3RME A;  2WLZ A;  2PV1 A;  1JNS A;  2KR7 A;  3WIJ A;  1ZU8 A;  4HBE A;  3TC5 A;  1ITX A;  3O5R A;  1ZK6 A;  4L3N A;  4MNM A;  3FAP A;  1W1V A;  1W9U A;  3CGN A;  1W1P A;  1ZBC A;  3G6M A;  4MNL A;  3KAG A;  4ITZ A;  4MTV A;  3H9R B;  4ODK A;  3O5P A;  1HKJ A;  5HW6 A;  3O5K A;  4U84 A;  4ODO A;  3B9D A;  3CGM A;  4DH0 A;  1E6N A;  2M08 A;  3IKD A;  3ARX A;  2ZR6 A;  1R9H A;  4ODN A;  1J4R A;  2WLY A;  4C02 B;  1JNT A;  3O5J A;  1VF8 A;  1D7I A;  2PI6 A;  1QPF A;  3AS3 A;  2N87 A;  4LGX A;  3O5O A;  4JFK A;  2QF8 A;  4Z2H A;  4JFM A;  5B8I C;  1FKK A;  3PRD A;  3JXV A;  1WB0 A;  4JYS A;  4NNR A;  4DZ3 A;  3KAF A;  1FD9 A;  4MPK A;  4DT4 A;  1HKM A;  3ARW A;  4HAR A;  2RUD A;  2MNT A;  4DRI A;  4LAY A;  3W4R A;  2VCD A;  2FKE A;  1H0I A;  1E6P A;  1FKB A;  3WQV A;  2ESC A;  2MF9 A;  1TCO C;  2UZ5 A;  2LKN A;  3CHC A;  3NTP A;  1KT0 A;  1JND A;  2KFW A;  2KE0 A;  4DRK A;  1L1P A;  3ARV A;  2PPN A;  3KAH A;  1J4H A;  2MLZ A;  5I98 A;  2XPA A;  1FKH A;  1LG1 A;  2O92 A;  2DT1 A;  5HT1 A;  2OFN A;  1W9P A;  2A3B A;  2XP3 A;  4J4O A;  4S3J A;  3I6C A;  4ODR A;  5DIT A;  3IK8 A;  1HKI A;  1ZBV A;  4JFL A;  2A3A A;  4TNS A;  3UI4 A;  5HBF A;  3ALF A;  4ZS6 A;  1GUV A;  3ARQ A;  5DF0 A;  3B9A A;  1ZBW A;  1FKS A;  4QT3 A;  2ZQT A;  4QZV B;  3QOK A;  2D9F A;  2ZR4 A;  2ZQU A;  1KT1 A;  4DWS C;  1U79 A;  3RM4 A;  3PR9 A;  3ARP A;  4P8X A;  4ZPV R;  4IQC A;  1O6I A;  1F8A B;  3O5I A;  5DEZ A;  4WJX A;  2WM0 A;  4W9O A;  1BL4 A;  1FKD A;  1N1A A;  2B31 A;  2RUC A;  5HWB A;  2OLH A;  1FKJ A;  3WKZ A;  3KZ7 A;  4LAV A;  4IPX A;  4DRQ A;  1EQ3 A;  4DWS B;  4DIP A;  4LAW A;  2PBC A;  2XP7 A;  1C9H A;  1LJY A;  5DIV A;  1GPF A;  3B7X A;  3CH9 A;  3ARR A;  1KFW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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