5GPGA

Co-crystal structure of the fk506 binding domain of human fkbp25, rapamycin and the frb domain of human mtor
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
117
structure length
110
Chain Sequence
SPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Proximity-Directed Labeling Reveals a New Rapamycin-Induced Heterodimer of FKBP25 and FRB in Live Cells
pubmed doi rcsb
molecule tags Isomerase/transferase
source organism Homo sapiens
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP3
total genus 25
structure length 110
sequence length 117
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2016-08-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00254 FKBP_C FKBP-type peptidyl-prolyl cis-trans isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.50.40 Alpha Beta Roll Chitinase A; domain 3 Chitinase A; domain 3 5gpgA00
2PV3A 2Q5AA 2ZQVA 4DROA 4JFLA 4N19A 2KR7A 1D7HA 1KT0A 3IKDA 2LJ4A 4GIVA 3RGCA 3UI5A 1JVWA 2PPOA 2RUQA 1J4IA 4BF8A 1EQ3A 3IK8A 4R0XA 4ODKA 1Y0OA 3CGNA 4JFMA 4ODRA 2N87A 2F4EA 3UQAA 2M08A 4QIBA 2MPHA 1D7JA 4ODLA 2ZQUA 4LAYA 3UQIA 1Q6UA 3NI6A 2K8IA 3FAPA 5GPGA 3MDYB 4DT4A 1QZ2A 3H9RB 4TW6A 1D6OA 2D9FA 4LAWA 2MLZA 4DZ3A 4W9PA 2RURA 4DIPA 2XP4A 3O5DA 4FAPA 5DITA 4ODQA 1FKKA 2M2AA 3UI6A 2L2SA 4NNRA 2ITKA 3KZ7A 1EYMA 3UQBA 1F40A 4IPXA 1QPFA 2XP8A 3O5PA 3PRDA 3EY6A 1Q6HA 3KAIA 4G50A 4U84A 4DRKA 4DZ2A 1TCOC 3O5KA 2KE0A 1A7XA 2XPBA 3VAWA 4ODOA 1FKIA 1QPLA 2ZR5A 1FKBA 3GPKA 3JXVA 4LAXA 3NRKA 1J4RA 5I98A 3KCEA 4FN2A 4QT3A 2PPNA 5HWBA 1FKGA 3ODKA 4J4OA 2DG4A 2PV1A 3B7XA 2LGOA 3JYMA 1N1AA 3JYJA 2PV2A 3O5MA 2RUDA 4ODPA 4G2PA 1J4HA 3WH0A 1NSGA 2MF9A 1R9HA 3NTPA 3KADA 4MSPA 1Q6IA 4TW8A 2IF4A 3TDBA 3O5RA 4QT2A 1T11A 1W26A 2XP3A 2ZQSA 4TW7A 1C9HA 2M1IA 3KAHA 2KI3A 1FKTA 3KAGA 4LAVA 4DRQA 4J4NA 3IHZA 4JFIA 3UF8A 3O5FA 4TYOA 4TNSA 4DRHA 5J6EA 5HW8A 4JYSA 2VN1A 5D75A 2XP9A 4DRIA 4O2TA 2XP7A 1HXVA 3TCZA 1M5YA 1FKFA 2ZR4A 1FKRA 2ZQTA 1NMVA 2F2DA 4U85A 2LKNA 4C02B 4DRJA 4ODNA 4JFKA 2DG9A 3KACA 1YW5A 4DRNA 5HW7A 2Y78A 1ROUA 1FKSA 3O5QA 1Q1CA 1PINA 2AWGA 3O5IA 1J6YA 1JNSA 3RFWA 1FKJA 2XP6A 1L1PA 3I6CA 1D7IA 1ZCNA 2UZ5A 2LPVA 3TC5A 5HUAA 1FD9A 1ROTA 3O5OA 3OOBA 1BKFA 3KABA 1FKDA 4W9OA 2KFWA 4U86A 1P5QA 1U79A 1JNTA 1YATA 3O5LA 1KT1A 1ZK6A 2MNTA 4GGQA 5HKGA 2PBCA 2OFNA 2VCDA 2F21A 2RSEA 1F8AB 3LUOA 5HTGA 5DIVA 1B6CA 1NMWA 4ITZA 2DG3A 1FKLA 2FKEA 3PRBA 4TX0A 2KO7A 3O5JA 5HT1A 4IQCA 1FAPA 1PBKA 2MLXA 3PA7A 3IKGA 5DIUA 4DRPA 4DH0A 3O5EA 4MGVA 3O5GA 1FJDA 2RQSA 5HWCA 1FKHA 5HW6A 2FAPA 2MLYA 2PPPA 5B8IC 5BXJA 2XP5A 3CGMA 3KAFA 4ODMA 2JZVA 4IQ2A 4JFJA 2ZR6A 3UI4A 4W9QA 1BL4A 2KGJA 2XPAA 4DRMA 2RUCA
chains in the Genus database with same CATH superfamily
4DROA 4JFLA 4N19A 1E6ZA 3IKDA 2LJ4A 4GIVA 2FDMA 2PPOA 1LL4A 3IK8A 4ODRA 3AROA 3ARWA 4ODLA 2ZQUA 3FXYA 3MDYB 4DT4A 4TW6A 5J6EA 1ZB5A 4ODQA 1FKKA 1W9PA 2L2SA 4NNRA 4ZPTR 2ITKA 4MAVA 4IPXA 3PRDA 4U84A 3EY6A 4DZ2A 4S3JA 2KE0A 1W9UA 4ODOA 4WKAA 3NRKA 1J4RA 3KCEA 1SYTA 1GOIA 2DG4A 2LGOA 3JYMA 2RUDA 3WH0A 2MF9A 4MSPA 1UR9A 1H0GA 1W26A 2A3EA 3CHFA 4DRQA 4XAKA 2F23A 3ARSA 2EULA 1LJYA 4MNLA 1HXVA 4MTVA 2ZR4A 1IX5A 4C02B 2DG9A 3O5QA 1ROUA 1VF8A 3ARVA 1OGGA 3RFWA 1FKJA 2XP6A 3I6CA 3TC5A 2O92A 2DT2A 3KABA 4Z2LA 1JNTA 1JNSA 2PBCA 2VCDA 1F8AB 3RMEA 1NWSA 1B6CA 2FKEA 4TX0A 4IQCA 1FAPA 1PBKA 3IKGA 3WD0A 4QZVB 1HKMA 1OWQA 5HWCA 1FKHA 5BXJA 2XP5A 4URIA 3KAFA 4ODMA 5DO2A 2JZVA 3WD4A 2XPAA 3WL1A 3CHCA 1E6RA 2RUCA 3GTYX 1E6NA 3AQUA 2AOSA 1D7HA 1KT0A 2YBUA 3B9AA 4R0XA 4ODKA 2N87A 2M08A 1W1VA 1SR0A 3RM8A 3ARQA 5GPGA 1HKJA 5GQBA 1D6OA 4DZ3A 4LAWA 4S3KA 4W9PA 5GPRA 2M2AA 4LGXA 1LL7A 3UQBA 1EIBA 2A3CA 2XP8A 3O5PA 3KAIA 2XPBA 3VAWA 1FKIA 1FKBA 3GPKA 4LAXA 2WK2A 4P8WA 2DPEA 5HWBA 4MPKA 1FKGA 1CTNA 1D2KA 3B7XA 1LG2A 2PV2A 3O5MA 1NWTA 1R9HA 1GPFA 3BMBA 3TDBA 3O5RA 5DF0A 1T11A 1C9HA 4ML4A 4LAVA 1ZU8A 3WKZA 4HARA 4DRHA 5HW8A 4JYSA 4HBOA 5D75A 2XP9A 4DRIA 4O2TA 4W5UA 2DSZA 1LQ0A 1M5YA 1FKRA 2F2DA 2A3AA 2LKNA 4DWSB 1HJWA 5HW7A 3CHEA 1J6YA 1X6NA 1ZBVA 2P4VA 1E44A 1ZCNA 2UZ5A 2LPVA 1FD9A 1ROTA 1BKFA 1WB0A 1FKDA 2YBTA 1XHGA 1YATA 4GGQA 2B31A 1ZK6A 2IUZA 3LUOA 5HTGA 5DIVA 2PI6A 2DG3A 1FKLA 4ITZA 3PRBA 2KO7A 3WD3A 3PA7A 2A3BA 4DRPA 3ARRA 3O5GA 2DSUA 1FJDA 2FAPA 2MLYA 4IT6A 2ZR6A 3AS1A 4ZPWR 4W9QA 4ZS6A 1X6LA 3ARYA 2PV3A 2ZQVA 1EDQA 2RUQA 4BF8A 1J4IA 3WIJA 1FFQA 1Y0OA 3CGNA 2WM0A 1HKIA 4JFMA 2MPHA 4P8VA 2DSVA 1D7JA 3B9EA 1Q6UA 3NI6A 4MNKA 3CZ8A 1QZ2A 3H9RB 2MLZA 2RURA 4DIPA 2XP4A 3O5DA 3AS2A 4DWSA 3WD2A 1F40A 3ARUA 1E15A 1QPFA 4G50A 4Z2GA 1A7XA 4WJXA 1QPLA 2ZR5A 1ITXA 5I98A 4QT3A 4FN2A 3ODKA 1TFVA 4IT4A 2PV1A 1JNEA 3W4RA 2O9OA 4KQZA 1LL6A 4ODPA 3ALFA 1J4HA 1NSGA 4P8XA 3KADA 1EHNA 1Q6IA 3G6LA 2IF4A 4QT2A 2DT0A 2XP3A 3G6MA 4HBEA 3KAGA 4J4NA 4JFIA 2DT3A 2WLYA 4UDMA 2G8ZA 4WIWA 3QOKA 3BXWA 2VN1A 1E6PA 3WD1A 4WKFA 2ZQTA 1NWUA 4Z2HA 1E9LA 4Q22A 4DRJA 4ODNA 4JFKA 3KACA 4DRNA 1YW5A 4P8UA 3CH9A 2Y78A 1FKSA 3O5IA 1Q1CA 1PINA 2AWGA 4Z2IA 1L1PA 1O6IA 3AS3A 4Q7NA 3O5OA 3OOBA 4W9OA 1HKKA 5HBFA 1WNOA 1U79A 1W1TA 3O5LA 1KT1A 2MNTA 4Z2JA 2F21A 3WL0A 1HJXA 5HT1A 3O5JA 2MLXA 2DSWA 4DH0A 3O5EA 5B8IC 3CGMA 4IQ2A 4JFJA 3UI4A 3OA5A 1BL4A 3WQVA 2ETNA 4MNMA 4DRMA 4NZCA 1WAWA 4L3NA 1NWRA 2Q5AA 2B5UB 4PTMA 3B8SA 2KR7A 1ZBKA 1K9TA 3RGCA 3UI5A 1JVWA 2DT1A 1EQ3A 1W9VA 3RM4A 2F4EA 3UQAA 4Z2KA 4QIBA 4LAYA 3UQIA 2K8IA 3FAPA 1HJVA 4DWSD 2D9FA 4FAPA 5DITA 3ALGA 3UI6A 2G41A 3EIPA 1ZBWA 1EYMA 3KZ7A 3CHDA 3ARXA 4DRKA 1Q6HA 1ZL1A 1TCOC 3O5KA 2WLZA 3WQWA 3JXVA 4ZPVR 2PPNA 4J4OA 1JNDA 5JH8A 1N1AA 3JYJA 2OLHA 4G2PA 3NTPA 4KR0B 4L72B 4TW8A 1FFRA 2ZQSA 1OGBA 1NH6A 4TW7A 2M1IA 3KAHA 2KI3A 1FKTA 3IHZA 3UF8A 3O5FA 1XRVA 4TYOA 1KFWA 4TNSA 1ZBCA 1GRJA 3AS0A 2XP7A 3TCZA 1FKFA 1NMVA 4U85A 1UR8A 5DEZA 4WKHA 1W1PA 1JCHB 1RD6A 1LG1A 3FY1A 3ARTA 1D7IA 5HUAA 2KFWA 3ARZA 4U86A 1P5QA 5HKGA 2OFNA 2RSEA 4AY1A 3ARPA 1NMWA 3PR9A 2PN0A 3RM9A 3B9DA 5DIUA 2ESCA 1H0IA 4MGVA 4NSBA 3PRAA 2RQSA 5HW6A 2PPPA 1W1YA 1GUVA 4DWSC 4MNJA 4R5EA 2QF8A 2KGJA 4WK9A 3GU0A
chains in the Genus database with same CATH topology
4DROA 4JFLA 4N19A 1E6ZA 3IKDA 2LJ4A 4GIVA 2FDMA 2PPOA 1LL4A 3IK8A 4ODRA 3AROA 3ARWA 4ODLA 2ZQUA 3FXYA 3MDYB 4DT4A 4TW6A 5J6EA 1ZB5A 4ODQA 1FKKA 1W9PA 2L2SA 4NNRA 4ZPTR 2ITKA 4MAVA 4IPXA 3PRDA 4U84A 3EY6A 4DZ2A 4S3JA 2KE0A 1W9UA 4ODOA 4WKAA 3NRKA 1J4RA 3KCEA 1SYTA 1GOIA 2DG4A 2LGOA 3JYMA 2RUDA 3WH0A 2MF9A 4MSPA 1UR9A 1H0GA 1W26A 2A3EA 3CHFA 4DRQA 4XAKA 3ARSA 1LJYA 4MNLA 1HXVA 4MTVA 2ZR4A 1IX5A 4C02B 2DG9A 3O5QA 1ROUA 1VF8A 1OGGA 3ARVA 3RFWA 1FKJA 2XP6A 3I6CA 3TC5A 2O92A 2DT2A 3KABA 4Z2LA 1JNTA 1JNSA 2PBCA 2VCDA 1F8AB 3RMEA 1NWSA 1B6CA 2FKEA 4TX0A 4IQCA 1FAPA 1PBKA 3IKGA 3WD0A 4QZVB 1HKMA 1OWQA 5HWCA 1FKHA 5BXJA 2XP5A 4URIA 3KAFA 4ODMA 5DO2A 2JZVA 3WD4A 2XPAA 3WL1A 3CHCA 1E6RA 2RUCA 1E6NA 3AQUA 2AOSA 1D7HA 1KT0A 2YBUA 3B9AA 4R0XA 4ODKA 2N87A 2M08A 1W1VA 1SR0A 3RM8A 3ARQA 5GPGA 1HKJA 5GQBA 1D6OA 4DZ3A 4LAWA 4S3KA 4W9PA 5GPRA 2M2AA 4LGXA 1LL7A 3UQBA 1EIBA 2A3CA 2XP8A 3O5PA 3KAIA 2XPBA 3VAWA 1FKIA 1FKBA 3GPKA 4LAXA 2WK2A 4P8WA 2DPEA 5HWBA 4MPKA 1FKGA 1CTNA 1D2KA 3B7XA 1LG2A 2PV2A 3O5MA 1NWTA 1R9HA 1GPFA 3TDBA 3O5RA 5DF0A 1T11A 1C9HA 4ML4A 4LAVA 1ZU8A 3WKZA 4HARA 4DRHA 5HW8A 4JYSA 4HBOA 5D75A 2XP9A 4DRIA 4O2TA 4W5UA 2DSZA 1LQ0A 1M5YA 1FKRA 2F2DA 2A3AA 2LKNA 4DWSB 1HJWA 5HW7A 3CHEA 1J6YA 1X6NA 1ZBVA 1ZCNA 2UZ5A 2LPVA 1FD9A 1ROTA 1BKFA 1WB0A 1FKDA 2YBTA 1XHGA 1YATA 4GGQA 2B31A 1ZK6A 2IUZA 3LUOA 5HTGA 5DIVA 2PI6A 2DG3A 1FKLA 4ITZA 3PRBA 2KO7A 3WD3A 3PA7A 2A3BA 4DRPA 3ARRA 3O5GA 2DSUA 1FJDA 2FAPA 2MLYA 4IT6A 2ZR6A 3AS1A 4ZPWR 4W9QA 4ZS6A 1X6LA 3ARYA 2PV3A 2ZQVA 1EDQA 2RUQA 4BF8A 1J4IA 3WIJA 1FFQA 1Y0OA 3CGNA 2WM0A 1HKIA 4JFMA 2MPHA 4P8VA 2DSVA 1D7JA 3B9EA 1Q6UA 3NI6A 4MNKA 3CZ8A 1QZ2A 3H9RB 2MLZA 2RURA 4DIPA 2XP4A 3O5DA 3AS2A 4DWSA 3WD2A 1F40A 3ARUA 1E15A 1QPFA 4G50A 4Z2GA 1A7XA 4WJXA 1QPLA 2ZR5A 1ITXA 5I98A 4QT3A 4FN2A 3ODKA 1TFVA 4IT4A 2PV1A 1JNEA 3W4RA 2O9OA 4KQZA 1LL6A 4ODPA 3ALFA 1J4HA 1NSGA 4P8XA 3KADA 1EHNA 1Q6IA 3G6LA 2IF4A 4QT2A 2DT0A 2XP3A 3G6MA 4HBEA 3KAGA 4J4NA 4JFIA 2DT3A 2WLYA 2G8ZA 4WIWA 3QOKA 3BXWA 2VN1A 1E6PA 3WD1A 4WKFA 2ZQTA 1NWUA 4Z2HA 1E9LA 4Q22A 4DRJA 4ODNA 4JFKA 3KACA 4DRNA 1YW5A 4P8UA 3CH9A 2Y78A 1FKSA 3O5IA 1Q1CA 1PINA 2AWGA 4Z2IA 1L1PA 1O6IA 3AS3A 4Q7NA 3O5OA 3OOBA 4W9OA 1HKKA 5HBFA 1WNOA 1U79A 1W1TA 3O5LA 1KT1A 2MNTA 4Z2JA 2F21A 3WL0A 1HJXA 5HT1A 3O5JA 2MLXA 2DSWA 4DH0A 3O5EA 5B8IC 3CGMA 4IQ2A 4JFJA 3UI4A 3OA5A 1BL4A 3WQVA 4MNMA 4DRMA 4NZCA 1WAWA 4L3NA 1NWRA 2Q5AA 4PTMA 3B8SA 2KR7A 1ZBKA 1K9TA 3RGCA 3UI5A 1JVWA 2DT1A 1EQ3A 1W9VA 3RM4A 2F4EA 3UQAA 4Z2KA 4QIBA 4LAYA 3UQIA 2K8IA 3FAPA 1HJVA 4DWSD 2D9FA 4FAPA 5DITA 3ALGA 3UI6A 2G41A 1ZBWA 1EYMA 3KZ7A 3CHDA 3ARXA 4DRKA 1Q6HA 1ZL1A 1TCOC 3O5KA 2WLZA 3WQWA 3JXVA 4ZPVR 2PPNA 4J4OA 1JNDA 5JH8A 1N1AA 3JYJA 2OLHA 4G2PA 3NTPA 4KR0B 4L72B 4TW8A 1FFRA 2ZQSA 1OGBA 1NH6A 4TW7A 2M1IA 3KAHA 2KI3A 1FKTA 3IHZA 3UF8A 3O5FA 1XRVA 4TYOA 1KFWA 4TNSA 1ZBCA 3AS0A 2XP7A 3TCZA 1FKFA 1NMVA 4U85A 1UR8A 5DEZA 4WKHA 1W1PA 1RD6A 1LG1A 3FY1A 3ARTA 1D7IA 5HUAA 2KFWA 3ARZA 4U86A 1P5QA 5HKGA 2OFNA 2RSEA 4AY1A 3ARPA 1NMWA 3PR9A 3RM9A 3B9DA 5DIUA 2ESCA 1H0IA 4MGVA 4NSBA 3PRAA 2RQSA 5HW6A 2PPPA 1W1YA 1GUVA 4DWSC 4MNJA 4R5EA 2QF8A 2KGJA 4WK9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PV3 A;  2Q5A A;  2ZQV A;  4DRO A;  4JFL A;  4N19 A;  2KR7 A;  1D7H A;  1KT0 A;  3IKD A;  2LJ4 A;  4GIV A;  3RGC A;  3UI5 A;  1JVW A;  2PPO A;  2RUQ A;  1J4I A;  4BF8 A;  1EQ3 A;  3IK8 A;  4R0X A;  4ODK A;  1Y0O A;  3CGN A;  4JFM A;  4ODR A;  2N87 A;  2F4E A;  3UQA A;  2M08 A;  4QIB A;  2MPH A;  1D7J A;  4ODL A;  2ZQU A;  4LAY A;  3UQI A;  1Q6U A;  3NI6 A;  2K8I A;  3FAP A;  5GPG A;  3MDY B;  4DT4 A;  1QZ2 A;  3H9R B;  4TW6 A;  1D6O A;  2D9F A;  4LAW A;  2MLZ A;  4DZ3 A;  4W9P A;  2RUR A;  4DIP A;  2XP4 A;  3O5D A;  4FAP A;  5DIT A;  4ODQ A;  1FKK A;  2M2A A;  3UI6 A;  2L2S A;  4NNR A;  2ITK A;  3KZ7 A;  1EYM A;  3UQB A;  1F40 A;  4IPX A;  1QPF A;  2XP8 A;  3O5P A;  3PRD A;  3EY6 A;  1Q6H A;  3KAI A;  4G50 A;  4U84 A;  4DRK A;  4DZ2 A;  1TCO C;  3O5K A;  2KE0 A;  1A7X A;  2XPB A;  3VAW A;  4ODO A;  1FKI A;  1QPL A;  2ZR5 A;  1FKB A;  3GPK A;  3JXV A;  4LAX A;  3NRK A;  1J4R A;  5I98 A;  3KCE A;  4FN2 A;  4QT3 A;  2PPN A;  5HWB A;  1FKG A;  3ODK A;  4J4O A;  2DG4 A;  2PV1 A;  3B7X A;  2LGO A;  3JYM A;  1N1A A;  3JYJ A;  2PV2 A;  3O5M A;  2RUD A;  4ODP A;  4G2P A;  1J4H A;  3WH0 A;  1NSG A;  2MF9 A;  1R9H A;  3NTP A;  3KAD A;  4MSP A;  1Q6I A;  4TW8 A;  2IF4 A;  3TDB A;  3O5R A;  4QT2 A;  1T11 A;  1W26 A;  2XP3 A;  2ZQS A;  4TW7 A;  1C9H A;  2M1I A;  3KAH A;  2KI3 A;  1FKT A;  3KAG A;  4LAV A;  4DRQ A;  4J4N A;  3IHZ A;  4JFI A;  3UF8 A;  3O5F A;  4TYO A;  4TNS A;  4DRH A;  5J6E A;  5HW8 A;  4JYS A;  2VN1 A;  5D75 A;  2XP9 A;  4DRI A;  4O2T A;  2XP7 A;  1HXV A;  3TCZ A;  1M5Y A;  1FKF A;  2ZR4 A;  1FKR A;  2ZQT A;  1NMV A;  2F2D A;  4U85 A;  2LKN A;  4C02 B;  4DRJ A;  4ODN A;  4JFK A;  2DG9 A;  3KAC A;  1YW5 A;  4DRN A;  5HW7 A;  2Y78 A;  1ROU A;  1FKS A;  3O5Q A;  1Q1C A;  1PIN A;  2AWG A;  3O5I A;  1J6Y A;  1JNS A;  3RFW A;  1FKJ A;  2XP6 A;  1L1P A;  3I6C A;  1D7I A;  1ZCN A;  2UZ5 A;  2LPV A;  3TC5 A;  5HUA A;  1FD9 A;  1ROT A;  3O5O A;  3OOB A;  1BKF A;  3KAB A;  1FKD A;  4W9O A;  2KFW A;  4U86 A;  1P5Q A;  1U79 A;  1JNT A;  1YAT A;  3O5L A;  1KT1 A;  1ZK6 A;  2MNT A;  4GGQ A;  5HKG A;  2PBC A;  2OFN A;  2VCD A;  2F21 A;  2RSE A;  1F8A B;  3LUO A;  5HTG A;  5DIV A;  1B6C A;  1NMW A;  4ITZ A;  2DG3 A;  1FKL A;  2FKE A;  3PRB A;  4TX0 A;  2KO7 A;  3O5J A;  5HT1 A;  4IQC A;  1FAP A;  1PBK A;  2MLX A;  3PA7 A;  3IKG A;  5DIU A;  4DRP A;  4DH0 A;  3O5E A;  4MGV A;  3O5G A;  1FJD A;  2RQS A;  5HWC A;  1FKH A;  5HW6 A;  2FAP A;  2MLY A;  2PPP A;  5B8I C;  5BXJ A;  2XP5 A;  3CGM A;  3KAF A;  4ODM A;  2JZV A;  4IQ2 A;  4JFJ A;  2ZR6 A;  3UI4 A;  4W9Q A;  1BL4 A;  2KGJ A;  2XPA A;  4DRM A;  2RUC A; 
#chains in the Genus database with same CATH topology
 4DRO A;  4JFL A;  4N19 A;  1E6Z A;  3IKD A;  2LJ4 A;  4GIV A;  2FDM A;  2PPO A;  1LL4 A;  3IK8 A;  4ODR A;  3ARO A;  3ARW A;  4ODL A;  2ZQU A;  3FXY A;  3MDY B;  4DT4 A;  4TW6 A;  5J6E A;  1ZB5 A;  4ODQ A;  1FKK A;  1W9P A;  2L2S A;  4NNR A;  4ZPT R;  2ITK A;  4MAV A;  4IPX A;  3PRD A;  4U84 A;  3EY6 A;  4DZ2 A;  4S3J A;  2KE0 A;  1W9U A;  4ODO A;  4WKA A;  3NRK A;  1J4R A;  3KCE A;  1SYT A;  1GOI A;  2DG4 A;  2LGO A;  3JYM A;  2RUD A;  3WH0 A;  2MF9 A;  4MSP A;  1UR9 A;  1H0G A;  1W26 A;  2A3E A;  3CHF A;  4DRQ A;  4XAK A;  2F23 A;  3ARS A;  2EUL A;  1LJY A;  4MNL A;  1HXV A;  4MTV A;  2ZR4 A;  1IX5 A;  4C02 B;  2DG9 A;  3O5Q A;  1ROU A;  1VF8 A;  3ARV A;  1OGG A;  3RFW A;  1FKJ A;  2XP6 A;  3I6C A;  3TC5 A;  2O92 A;  2DT2 A;  3KAB A;  4Z2L A;  1JNT A;  1JNS A;  2PBC A;  2VCD A;  1F8A B;  3RME A;  1NWS A;  1B6C A;  2FKE A;  4TX0 A;  4IQC A;  1FAP A;  1PBK A;  3IKG A;  3WD0 A;  4QZV B;  1HKM A;  1OWQ A;  5HWC A;  1FKH A;  5BXJ A;  2XP5 A;  4URI A;  3KAF A;  4ODM A;  5DO2 A;  2JZV A;  3WD4 A;  2XPA A;  3WL1 A;  3CHC A;  1E6R A;  2RUC A;  3GTY X;  1E6N A;  3AQU A;  2AOS A;  1D7H A;  1KT0 A;  2YBU A;  3B9A A;  4R0X A;  4ODK A;  2N87 A;  2M08 A;  1W1V A;  1SR0 A;  3RM8 A;  3ARQ A;  5GPG A;  1HKJ A;  5GQB A;  1D6O A;  4DZ3 A;  4LAW A;  4S3K A;  4W9P A;  5GPR A;  2M2A A;  4LGX A;  1LL7 A;  3UQB A;  1EIB A;  2A3C A;  2XP8 A;  3O5P A;  3KAI A;  2XPB A;  3VAW A;  1FKI A;  1FKB A;  3GPK A;  4LAX A;  2WK2 A;  4P8W A;  2DPE A;  5HWB A;  4MPK A;  1FKG A;  1CTN A;  1D2K A;  3B7X A;  1LG2 A;  2PV2 A;  3O5M A;  1NWT A;  1R9H A;  1GPF A;  3BMB A;  3TDB A;  3O5R A;  5DF0 A;  1T11 A;  1C9H A;  4ML4 A;  4LAV A;  1ZU8 A;  3WKZ A;  4HAR A;  4DRH A;  5HW8 A;  4JYS A;  4HBO A;  5D75 A;  2XP9 A;  4DRI A;  4O2T A;  4W5U A;  2DSZ A;  1LQ0 A;  1M5Y A;  1FKR A;  2F2D A;  2A3A A;  2LKN A;  4DWS B;  1HJW A;  5HW7 A;  3CHE A;  1J6Y A;  1X6N A;  1ZBV A;  2P4V A;  1E44 A;  1ZCN A;  2UZ5 A;  2LPV A;  1FD9 A;  1ROT A;  1BKF A;  1WB0 A;  1FKD A;  2YBT A;  1XHG A;  1YAT A;  4GGQ A;  2B31 A;  1ZK6 A;  2IUZ A;  3LUO A;  5HTG A;  5DIV A;  2PI6 A;  2DG3 A;  1FKL A;  4ITZ A;  3PRB A;  2KO7 A;  3WD3 A;  3PA7 A;  2A3B A;  4DRP A;  3ARR A;  3O5G A;  2DSU A;  1FJD A;  2FAP A;  2MLY A;  4IT6 A;  2ZR6 A;  3AS1 A;  4ZPW R;  4W9Q A;  4ZS6 A;  1X6L A;  3ARY A;  2PV3 A;  2ZQV A;  1EDQ A;  2RUQ A;  4BF8 A;  1J4I A;  3WIJ A;  1FFQ A;  1Y0O A;  3CGN A;  2WM0 A;  1HKI A;  4JFM A;  2MPH A;  4P8V A;  2DSV A;  1D7J A;  3B9E A;  1Q6U A;  3NI6 A;  4MNK A;  3CZ8 A;  1QZ2 A;  3H9R B;  2MLZ A;  2RUR A;  4DIP A;  2XP4 A;  3O5D A;  3AS2 A;  4DWS A;  3WD2 A;  1F40 A;  3ARU A;  1E15 A;  1QPF A;  4G50 A;  4Z2G A;  1A7X A;  4WJX A;  1QPL A;  2ZR5 A;  1ITX A;  5I98 A;  4QT3 A;  4FN2 A;  3ODK A;  1TFV A;  4IT4 A;  2PV1 A;  1JNE A;  3W4R A;  2O9O A;  4KQZ A;  1LL6 A;  4ODP A;  3ALF A;  1J4H A;  1NSG A;  4P8X A;  3KAD A;  1EHN A;  1Q6I A;  3G6L A;  2IF4 A;  4QT2 A;  2DT0 A;  2XP3 A;  3G6M A;  4HBE A;  3KAG A;  4J4N A;  4JFI A;  2DT3 A;  2WLY A;  4UDM A;  2G8Z A;  4WIW A;  3QOK A;  3BXW A;  2VN1 A;  1E6P A;  3WD1 A;  4WKF A;  2ZQT A;  1NWU A;  4Z2H A;  1E9L A;  4Q22 A;  4DRJ A;  4ODN A;  4JFK A;  3KAC A;  4DRN A;  1YW5 A;  4P8U A;  3CH9 A;  2Y78 A;  1FKS A;  3O5I A;  1Q1C A;  1PIN A;  2AWG A;  4Z2I A;  1L1P A;  1O6I A;  3AS3 A;  4Q7N A;  3O5O A;  3OOB A;  4W9O A;  1HKK A;  5HBF A;  1WNO A;  1U79 A;  1W1T A;  3O5L A;  1KT1 A;  2MNT A;  4Z2J A;  2F21 A;  3WL0 A;  1HJX A;  5HT1 A;  3O5J A;  2MLX A;  2DSW A;  4DH0 A;  3O5E A;  5B8I C;  3CGM A;  4IQ2 A;  4JFJ A;  3UI4 A;  3OA5 A;  1BL4 A;  3WQV A;  2ETN A;  4MNM A;  4DRM A;  4NZC A;  1WAW A;  4L3N A;  1NWR A;  2Q5A A;  2B5U B;  4PTM A;  3B8S A;  2KR7 A;  1ZBK A;  1K9T A;  3RGC A;  3UI5 A;  1JVW A;  2DT1 A;  1EQ3 A;  1W9V A;  3RM4 A;  2F4E A;  3UQA A;  4Z2K A;  4QIB A;  4LAY A;  3UQI A;  2K8I A;  3FAP A;  1HJV A;  4DWS D;  2D9F A;  4FAP A;  5DIT A;  3ALG A;  3UI6 A;  2G41 A;  3EIP A;  1ZBW A;  1EYM A;  3KZ7 A;  3CHD A;  3ARX A;  4DRK A;  1Q6H A;  1ZL1 A;  1TCO C;  3O5K A;  2WLZ A;  3WQW A;  3JXV A;  4ZPV R;  2PPN A;  4J4O A;  1JND A;  5JH8 A;  1N1A A;  3JYJ A;  2OLH A;  4G2P A;  3NTP A;  4KR0 B;  4L72 B;  4TW8 A;  1FFR A;  2ZQS A;  1OGB A;  1NH6 A;  4TW7 A;  2M1I A;  3KAH A;  2KI3 A;  1FKT A;  3IHZ A;  3UF8 A;  3O5F A;  1XRV A;  4TYO A;  1KFW A;  4TNS A;  1ZBC A;  1GRJ A;  3AS0 A;  2XP7 A;  3TCZ A;  1FKF A;  1NMV A;  4U85 A;  1UR8 A;  5DEZ A;  4WKH A;  1W1P A;  1JCH B;  1RD6 A;  1LG1 A;  3FY1 A;  3ART A;  1D7I A;  5HUA A;  2KFW A;  3ARZ A;  4U86 A;  1P5Q A;  5HKG A;  2OFN A;  2RSE A;  4AY1 A;  3ARP A;  1NMW A;  3PR9 A;  2PN0 A;  3RM9 A;  3B9D A;  5DIU A;  2ESC A;  1H0I A;  4MGV A;  4NSB A;  3PRA A;  2RQS A;  5HW6 A;  2PPP A;  1W1Y A;  1GUV A;  4DWS C;  4MNJ A;  4R5E A;  2QF8 A;  2KGJ A;  4WK9 A;  3GU0 A; 
#chains in the Genus database with same CATH homology
 4DRO A;  4JFL A;  4N19 A;  1E6Z A;  3IKD A;  2LJ4 A;  4GIV A;  2FDM A;  2PPO A;  1LL4 A;  3IK8 A;  4ODR A;  3ARO A;  3ARW A;  4ODL A;  2ZQU A;  3FXY A;  3MDY B;  4DT4 A;  4TW6 A;  5J6E A;  1ZB5 A;  4ODQ A;  1FKK A;  1W9P A;  2L2S A;  4NNR A;  4ZPT R;  2ITK A;  4MAV A;  4IPX A;  3PRD A;  4U84 A;  3EY6 A;  4DZ2 A;  4S3J A;  2KE0 A;  1W9U A;  4ODO A;  4WKA A;  3NRK A;  1J4R A;  3KCE A;  1SYT A;  1GOI A;  2DG4 A;  2LGO A;  3JYM A;  2RUD A;  3WH0 A;  2MF9 A;  4MSP A;  1UR9 A;  1H0G A;  1W26 A;  2A3E A;  3CHF A;  4DRQ A;  4XAK A;  3ARS A;  1LJY A;  4MNL A;  1HXV A;  4MTV A;  2ZR4 A;  1IX5 A;  4C02 B;  2DG9 A;  3O5Q A;  1ROU A;  1VF8 A;  1OGG A;  3ARV A;  3RFW A;  1FKJ A;  2XP6 A;  3I6C A;  3TC5 A;  2O92 A;  2DT2 A;  3KAB A;  4Z2L A;  1JNT A;  1JNS A;  2PBC A;  2VCD A;  1F8A B;  3RME A;  1NWS A;  1B6C A;  2FKE A;  4TX0 A;  4IQC A;  1FAP A;  1PBK A;  3IKG A;  3WD0 A;  4QZV B;  1HKM A;  1OWQ A;  5HWC A;  1FKH A;  5BXJ A;  2XP5 A;  4URI A;  3KAF A;  4ODM A;  5DO2 A;  2JZV A;  3WD4 A;  2XPA A;  3WL1 A;  3CHC A;  1E6R A;  2RUC A;  1E6N A;  3AQU A;  2AOS A;  1D7H A;  1KT0 A;  2YBU A;  3B9A A;  4R0X A;  4ODK A;  2N87 A;  2M08 A;  1W1V A;  1SR0 A;  3RM8 A;  3ARQ A;  5GPG A;  1HKJ A;  5GQB A;  1D6O A;  4DZ3 A;  4LAW A;  4S3K A;  4W9P A;  5GPR A;  2M2A A;  4LGX A;  1LL7 A;  3UQB A;  1EIB A;  2A3C A;  2XP8 A;  3O5P A;  3KAI A;  2XPB A;  3VAW A;  1FKI A;  1FKB A;  3GPK A;  4LAX A;  2WK2 A;  4P8W A;  2DPE A;  5HWB A;  4MPK A;  1FKG A;  1CTN A;  1D2K A;  3B7X A;  1LG2 A;  2PV2 A;  3O5M A;  1NWT A;  1R9H A;  1GPF A;  3TDB A;  3O5R A;  5DF0 A;  1T11 A;  1C9H A;  4ML4 A;  4LAV A;  1ZU8 A;  3WKZ A;  4HAR A;  4DRH A;  5HW8 A;  4JYS A;  4HBO A;  5D75 A;  2XP9 A;  4DRI A;  4O2T A;  4W5U A;  2DSZ A;  1LQ0 A;  1M5Y A;  1FKR A;  2F2D A;  2A3A A;  2LKN A;  4DWS B;  1HJW A;  5HW7 A;  3CHE A;  1J6Y A;  1X6N A;  1ZBV A;  1ZCN A;  2UZ5 A;  2LPV A;  1FD9 A;  1ROT A;  1BKF A;  1WB0 A;  1FKD A;  2YBT A;  1XHG A;  1YAT A;  4GGQ A;  2B31 A;  1ZK6 A;  2IUZ A;  3LUO A;  5HTG A;  5DIV A;  2PI6 A;  2DG3 A;  1FKL A;  4ITZ A;  3PRB A;  2KO7 A;  3WD3 A;  3PA7 A;  2A3B A;  4DRP A;  3ARR A;  3O5G A;  2DSU A;  1FJD A;  2FAP A;  2MLY A;  4IT6 A;  2ZR6 A;  3AS1 A;  4ZPW R;  4W9Q A;  4ZS6 A;  1X6L A;  3ARY A;  2PV3 A;  2ZQV A;  1EDQ A;  2RUQ A;  4BF8 A;  1J4I A;  3WIJ A;  1FFQ A;  1Y0O A;  3CGN A;  2WM0 A;  1HKI A;  4JFM A;  2MPH A;  4P8V A;  2DSV A;  1D7J A;  3B9E A;  1Q6U A;  3NI6 A;  4MNK A;  3CZ8 A;  1QZ2 A;  3H9R B;  2MLZ A;  2RUR A;  4DIP A;  2XP4 A;  3O5D A;  3AS2 A;  4DWS A;  3WD2 A;  1F40 A;  3ARU A;  1E15 A;  1QPF A;  4G50 A;  4Z2G A;  1A7X A;  4WJX A;  1QPL A;  2ZR5 A;  1ITX A;  5I98 A;  4QT3 A;  4FN2 A;  3ODK A;  1TFV A;  4IT4 A;  2PV1 A;  1JNE A;  3W4R A;  2O9O A;  4KQZ A;  1LL6 A;  4ODP A;  3ALF A;  1J4H A;  1NSG A;  4P8X A;  3KAD A;  1EHN A;  1Q6I A;  3G6L A;  2IF4 A;  4QT2 A;  2DT0 A;  2XP3 A;  3G6M A;  4HBE A;  3KAG A;  4J4N A;  4JFI A;  2DT3 A;  2WLY A;  2G8Z A;  4WIW A;  3QOK A;  3BXW A;  2VN1 A;  1E6P A;  3WD1 A;  4WKF A;  2ZQT A;  1NWU A;  4Z2H A;  1E9L A;  4Q22 A;  4DRJ A;  4ODN A;  4JFK A;  3KAC A;  4DRN A;  1YW5 A;  4P8U A;  3CH9 A;  2Y78 A;  1FKS A;  3O5I A;  1Q1C A;  1PIN A;  2AWG A;  4Z2I A;  1L1P A;  1O6I A;  3AS3 A;  4Q7N A;  3O5O A;  3OOB A;  4W9O A;  1HKK A;  5HBF A;  1WNO A;  1U79 A;  1W1T A;  3O5L A;  1KT1 A;  2MNT A;  4Z2J A;  2F21 A;  3WL0 A;  1HJX A;  5HT1 A;  3O5J A;  2MLX A;  2DSW A;  4DH0 A;  3O5E A;  5B8I C;  3CGM A;  4IQ2 A;  4JFJ A;  3UI4 A;  3OA5 A;  1BL4 A;  3WQV A;  4MNM A;  4DRM A;  4NZC A;  1WAW A;  4L3N A;  1NWR A;  2Q5A A;  4PTM A;  3B8S A;  2KR7 A;  1ZBK A;  1K9T A;  3RGC A;  3UI5 A;  1JVW A;  2DT1 A;  1EQ3 A;  1W9V A;  3RM4 A;  2F4E A;  3UQA A;  4Z2K A;  4QIB A;  4LAY A;  3UQI A;  2K8I A;  3FAP A;  1HJV A;  4DWS D;  2D9F A;  4FAP A;  5DIT A;  3ALG A;  3UI6 A;  2G41 A;  1ZBW A;  1EYM A;  3KZ7 A;  3CHD A;  3ARX A;  4DRK A;  1Q6H A;  1ZL1 A;  1TCO C;  3O5K A;  2WLZ A;  3WQW A;  3JXV A;  4ZPV R;  2PPN A;  4J4O A;  1JND A;  5JH8 A;  1N1A A;  3JYJ A;  2OLH A;  4G2P A;  3NTP A;  4KR0 B;  4L72 B;  4TW8 A;  1FFR A;  2ZQS A;  1OGB A;  1NH6 A;  4TW7 A;  2M1I A;  3KAH A;  2KI3 A;  1FKT A;  3IHZ A;  3UF8 A;  3O5F A;  1XRV A;  4TYO A;  1KFW A;  4TNS A;  1ZBC A;  3AS0 A;  2XP7 A;  3TCZ A;  1FKF A;  1NMV A;  4U85 A;  1UR8 A;  5DEZ A;  4WKH A;  1W1P A;  1RD6 A;  1LG1 A;  3FY1 A;  3ART A;  1D7I A;  5HUA A;  2KFW A;  3ARZ A;  4U86 A;  1P5Q A;  5HKG A;  2OFN A;  2RSE A;  4AY1 A;  3ARP A;  1NMW A;  3PR9 A;  3RM9 A;  3B9D A;  5DIU A;  2ESC A;  1H0I A;  4MGV A;  4NSB A;  3PRA A;  2RQS A;  5HW6 A;  2PPP A;  1W1Y A;  1GUV A;  4DWS C;  4MNJ A;  4R5E A;  2QF8 A;  2KGJ A;  4WK9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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