2O5JD

Crystal structure of the t. thermophilus rnap polymerase elongation complex with the ntp substrate analog
Total Genus 275
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
275
sequence length
1504
structure length
1264
Chain Sequence
KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGAADITQGLPRVIELFEARRPKAKAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEAVEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase/dna-rna hybrid
publication title Structural basis for substrate loading in bacterial RNA polymerase.
pubmed doi rcsb
molecule keywords 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP
total genus 275
structure length 1264
sequence length 1504
chains with identical sequence N
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2006-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00623 RNA_pol_Rpb1_2 RNA polymerase Rpb1, domain 2
D PF04983 RNA_pol_Rpb1_3 RNA polymerase Rpb1, domain 3
D PF04997 RNA_pol_Rpb1_1 RNA polymerase Rpb1, domain 1
D PF04998 RNA_pol_Rpb1_5 RNA polymerase Rpb1, domain 5
D PF05000 RNA_pol_Rpb1_4 RNA polymerase Rpb1, domain 4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.30 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 2o5jD05
1.10.274.100 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Enzyme I; Chain A, domain 2 2o5jD04
2.20.28.170 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2o5jD07
2.40.40.70 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2o5jD03
2E2HA 2YU9A 1TWCA 2A6ED 1TWGA 1TWAA 2WB1A 4QIWA 2A6HD 1TWFA 2JA6A 1WCMA 3GTMA 3GTJA 1TWHA 4AYBA 2VUMA 1R9TA 2A69D 2CW0D 1ZYRD 2E2IA 1HQMD 1IW7D 3GTGA 2NVXA 1K83A 2WAQA 2O5JD 3HKZA 1YNND 3CQZA 1I6VD 2R92A 1YNJD 2A68D 2BE5D 2B63A 1Y1WA 3GTKA 2R93A 4C2MA 3H0GA 1Y1VA 1SMYD 2JA5A 1I3QA 3FKIA 1I50A 3GTLA 2R7ZA 3GTQA 2Y0SA 3GTPA 2PMZA 1SFOA 3GTOA 2NVYA 2JA7A
chains in the Genus database with same CATH superfamily
1T6JA 2EY4E 4KB2A 3K5LA 1QQTA 3PO3L 2KI8A 1Q8IA 3QC8A 1GE9A 4AYBP 1WC2A 4GA5A 2R92L 2GAEA 1IU5A 3H97A 5AN9H 2X0OA 1BRFA 4ZM7A 5RXNA 2PSMC 1RYTA 4A93L 2O5JD 1AW8B 1PFVA 3IR5A 1H5NA 1RDVA 2A68D 2N3EA 4YWLA 3KYLA 2JA5A 5FTJA 3HU3A 2XJVA 2IV2X 1YUXA 5MLC9 3M3GA 5H4UA 3RZTA 1RYQA 3WWNB 2JI1A 5T5ID 5FTLA 4G6BA 1E18A 2M6PA 3QVDA 2R4GA 4H3TA 1R9TA 2HROA 2CW0D 1K4TA 4JAEA 1S30A 4POFA 4V2RA 3PIO1 3WVOA 1EJ9A 4NOMA 1BQ9A 2K2DA 4JP6A 3K5NA 3H3VM 1YK4A 1H7VA 2VK9A 4TPUA 4OYDB 2F5JA 3DMRA 4EJ3A 4ME3A 1DMSA 1ISEA 1TWFL 2JIQA 4TVMA 1VZIA 1SMUA 4KO8A 2AUSB 1NNQA 4QIWA 1R0JA 2PYAA 3J7Z1 3LWVB 1F4LA 1ODHA 2EZAA 3K5MA 1T6PA 4CS0A 3I4NL 1ZYMA 1LKMA 2V3BB 3LRDA 5CQGA 3K35A 1I50L 5K2ME 1E32A 1K83A 3LF9A 3HKZP 2PICA 3GTPL 1I6VD 4XXBB 3M4AA 2B5ID 3NFPI 5MFPA 3OUGA 2APOB 2JA7L 3H0GA 1WJVA 2Y0NA 2KN9A 5H1Sc 1QCSA 1TWHL 3S15L 5DYGA 1WQGA 2XJUA 1R0FA 1CZ5A 2PVEA 2XJQA 3PKJA 1PFUA 4RXNA 4BBSL 2JIOA 1TWAA 1TWFA 3LWPB 1FHMA 1OA9A 3MPSA 5C44L 3RYGA 2L0ZA 4CEIA 5MGNA 4X6AL 3X2IA 4JJOA 5M3ML 2LPJA 1B2OA 5GLXA 3EZAA 4C3JL 2E2JL 2AQCA 3JR7A 2V3VA 5FLML 1H0HA 5C3EL 2AE0X 1FHHA 5IYCL 3GTQA 2JA8L 3O5AA 3HOXL 5FTMA 3HOZL 4QIWP 5GADc 3X2GA 2WB1A 3KYWA 5FTKA 1SC7A 3FDJA 2VUMA 2B63L 2XJRA 3S1NL 1E5VA 2V0EA 1ZYRD 4KAWX 3GTGA 1WQFA 2K3QA 2WAQA 3SUMA 3IAYA 2XJPA 1N10A 1A31A 4ZN1B 3S1QL 1BW4A 1R0GA 3P9AA 4GA6A 3EZBA 3GTLA 1DX8A 5C18A 8RXNA 4AR6A 3QQ8A 1YUZA 4GFQA 1R5ZA 3NZ4A 3PO2L 1ZRPA 4KLNA 1TL8A 1EH1A 4C3IL 3HU1A 1R0IA 1SIWA 2E2IL 5B6CA 4AHCA 2JA6A 3ENGA 2A6HD 1RRJA 4ENGA 3U44A 4C5RA 2E7ZA 4BXXL 3LNLA 1WQHA 1LPQA 3LWQB 4CRZA 1HQMD 1V9MA 1R49A 1B71A 3LR8A 1BQ8A 1VCXA 3PLXB 2JIRA 1B13A 4YWMA 4AHXA 3MAQA 1S3SA 4A3JL 2R7ZL 4A3LL 4C5UA 4D7ZB 3GTKA 2E2HL 5DYIA 3GTOL 1TWCL 2XJTA 1SMYD 2MX8A 4D3ZA 1T9OA 2Y0SA 4BABA 3CF2A 2MX9A 1QYBA 3RZDL 3GTML 1SMWA 2J9UB 3SJRA 3H9CA 1AA6A 2WB1P 4BY7L 4FGUA 1YV1A 2NAPA 4AONB 5AI3A 1IS1A 1I6HL 1A36A 1E8JA 4FFTA 2Z3QB 2C6AA 2E2IA 1T9QA 2R93L 2CR8A 1PYUB 2WAQP 1R27A 1OGYA 4KDIA 3H9BA 1KQGA 1PT0A 2R92A 2CKCA 2RFKB 3X2NA 4FG4A 5FJ8L 1Z92B 2R7ZA 4NOHA 2V0FA 5GAHc 4A3FL 1BW3A 1WCML 2LTHA 1PPYA 2JIMA 2PMZA 1S24A 4C5SA 3H99A 3GTOA 2K3NA 2A6ED 1A35A 2NVTL 2CKAA 2G6GA 3GTMA 1EZBA 3HJWB 4NOKA 4FG2A 2KKDA 3M3YL 1LKPA 2X0PA 2PI8A 5IP9L 4AR4A 3QWZA 1EK8A 1IU6A 3K57A 2ZIXA 4WFN1 1YNND 4FBSA 4AHWA 3RZOL 3SUKA 4U671 1SFOL 4BAAA 5JSBB 1LKOA 5T5MD 3VPBE 2EZCA 2RDVA 2DSXA 2NVQL 4E6YA 1PQEA 3GTJL 3ZG6A 2G5DA 1QDNA 4GS7D 4LHNA 1Y698 2ENGA 4IP9A 4FYDA 1WCMA 3LR2A 2C6BA 2NVXL 3X2KA 2JI3A 3CQZL 1Y1WL 5DM61 4XGHA 4JS7A 4LMOA 2M4VA 3S2HL 1QCVA 1MIUA 2PPTA 3HJYB 1CAAA 5JVG1 5JVH1 5C1BA 4IP8A 3S2DL 2NVYL 1EZAA 1RWDA 2HVYC 1I50A 2MS3A 1UHEA 4AAYA 2AQLA 3PWFA 1PT1A 4AR3A 2H12A 3GTPA 4FERA 4AN8A 4LHLA 1PYQA 1SFOA 2JA7A 2BH0A 5MLC3 4ZN3B 1DMRA 1FDIA 1RR8C 3GTJA 1TWHA 1R0HA 4BY1L 4F3EA 3HOUL 1E61A 1T8IA 2YIIA 2EEOB 1DVBA 3A44A 1KQFA 3I4ML 2LPIA 3HOYL 2NVXA 2N1DB 3FKIL 3K7AL 1PZXA 2KQAA 4Y52L 3CQZA 5MF6A 2C45A 5M3FL 3P2AA 2F4QA 5M5XL 4NOLA 2V45A 3LWRB 4O26A 3D30A 4AHYA 1SEUA 1DD5A 1SMMA 2MQAA 3HOVL 3S16L 1Y4ZA 2FIOA 4A3EL 2ERJA 2VPWA 3TIWA 3X2OA 4POGA 2JA5L 1CZ4A 4AI2A 3SS2A 3HAXC 3PZAA 1YK5A 1TMOA 2B63A 4AVRA 3S14L 2HCZX 3X2PA 3FKIA 1TWGL 3B0AB 3PIP1 5IZ2A 1B2JA 2LKMB 1RDGA 4RV0A 3P8BA 4JLRC 1C09A 1G8KA 5DM71 2PJJA 4C2M1 5AI2A 4CEJA 3S17L 1E60A 2A69D 1NXEA 2Z3RB 2JIPA 4KODA 1LTLA 2QL0A 2X0QA 4Q5GA 4JAGA 1UHDA 3X2MA 3HKZA 1G8JA 3ML1A 3IR7A 5IY0A 2ERSA 4KC6A 4QCLA 4AR5A 3DU6A 3X2JA 2PVXA 1BE7A 4Y7NL 1BFYA 1Y2MA 2FIPA 1K4SA 5MFZA 5EPPA 2E2HA 1TWCA 5C9HA 1TWGA 3U4QA 3RZ6A 3LPEB 1IRNA 1K83L 1OWBA 4JAFA 2GMGA 5C4JL 1YLEA 2VPYA 3K59A 2PJHB 4V196 4CRYG 2M6OA 3H0GL 4A3KL 5GAEc 4A3GL 4KDLA 3EZEA 3IU3I 3DU5A 2LYIA 2M4YA 4L8IA 4C3HL 5C4XL 2NYDA 3QQCE 3IR6A 2R93A 3M4OL 2YU9L 7RXNA 1TWAL 2Y0SP 3K5OA 1VZGA 5EINC 4KB4A 4Q5VA 1W27A 1OWCA 2XJSA 2NYAA 3HU2A 4CQ5A 2HR5A 3J7Y1 1CR5A 1NXGA 3KYVA 3LWOB 4A3ML 4L48A 4BBRL 5GLYA 1RB9A 1NH3A 3S1ML 4C6GA 3WWLA 3GTQL 3CZBA 2K3OA 4AZDA 3X2LA 3PL5A 4JP7A 5GM9A 2AYJA 3X2HA 1IROA 3SUJA 1S2ZA 3KYXA 4AI1A 4JCWA 1PFWA 1HD5A 4A3BL 2B9SB 4AI3A 4FXDA 5IP7L 6RXNA 3B08B 2VUML 1FDOA 2PMZP 5EIOC 2YU9A 1Y5IA 3K58A 5GAGc 1VC3B 3GTGL 1PQHA 5JSNB 2DMRA 3KYYA 4AYBA 3TM7B 2LCQA 3LR6A 4CEHA 1ZC1A 4B8CD 4KDDA 2VPXA 2VL6A 3SULA 5IYDL 1Y1VL 3GTLL 1I3QL 2MP0A 4A3IL 5GLFA 1R7RA 1Y1WA 4DMRA 4C2MA 1WLFA 1PQFA 2JA6L 2YUJA 4A3CL 1T9PA 5M5YL 4A3DL 2PNWA 4AI0A 4AHZA 2NVYA 1PFYA 2JI2A 1TGOA 3LHPS 1CADA 1OA7A 2VPZA 1JYBA 3QQ7A 1EU1A 1L8FA 4V2QA 3S1RL 1P7PA 3GTKL 2HWGA 5IYBL 5FTNA 1IW7D 4JADA 3MQKB 1YNJD 2BE5D 3KYUA 4UY81 1VZHA 3PKIA 4K9FA 1Y1VA 5M5WL 1I3QA 3HOWL 4D3YA 1Q16A 3MSUA 4AOKB 2EZBA 1R9TL
chains in the Genus database with same CATH topology
4KB2A 3K5LA 2KI8A 1Q8IA 3QC8A 1GE9A 4GA5A 2GAEA 1IU5A 5AN9H 2X0OA 1BRFA 5RXNA 2PSMC 1RYTA 2O5JD 1AW8B 3IR5A 1H5NA 1RDVA 2A68D 2N3EA 4YWLA 3KYLA 2JA5A 5FTJA 3HU3A 2XJVA 2IV2X 1YUXA 5MLC9 3RZTA 1RYQA 3WWNB 2JI1A 5T5ID 5FTLA 4G6BA 1E18A 2M6PA 3QVDA 2R4GA 4H3TA 1R9TA 2CW0D 1K4TA 4JAEA 1S30A 4POFA 3PIO1 3WVOA 1EJ9A 4NOMA 1BQ9A 2K2DA 3K5NA 1H7VA 1YK4A 2VK9A 4TPUA 4OYDB 2F5JA 3DMRA 4EJ3A 4ME3A 1DMSA 1ISEA 2JIQA 4TVMA 1VZIA 1SMUA 4KO8A 1NNQA 4QIWA 1R0JA 2PYAA 3J7Z1 1ODHA 3K5MA 4CS0A 1LKMA 2V3BB 3LRDA 5CQGA 3K35A 5K2ME 1E32A 1K83A 3LF9A 2PICA 1I6VD 4XXBB 3M4AA 2B5ID 3NFPI 5MFPA 3OUGA 3H0GA 1WJVA 2Y0NA 2KN9A 5H1Sc 1QCSA 5DYGA 1WQGA 2XJUA 1R0FA 1CZ5A 2PVEA 2XJQA 3PKJA 4RXNA 2JIOA 1TWAA 1TWFA 1FHMA 3MPSA 3RYGA 2L0ZA 4CEIA 5MGNA 2LPJA 1B2OA 2V3VA 1H0HA 2AE0X 1FHHA 3GTQA 3O5AA 5FTMA 5GADc 2WB1A 3KYWA 5FTKA 1SC7A 2VUMA 2XJRA 1E5VA 2V0EA 1ZYRD 4KAWX 3GTGA 1WQFA 2K3QA 2WAQA 3IAYA 2XJPA 1A31A 4ZN1B 1R0GA 3P9AA 4GA6A 3GTLA 1DX8A 5C18A 8RXNA 4AR6A 3QQ8A 1YUZA 4GFQA 1R5ZA 1ZRPA 4KLNA 1TL8A 1EH1A 3HU1A 1R0IA 1SIWA 5B6CA 4AHCA 2JA6A 2A6HD 1RRJA 3U44A 2E7ZA 3LNLA 1WQHA 1LPQA 4CRZA 1HQMD 1V9MA 1R49A 1B71A 3LR8A 1BQ8A 1VCXA 3PLXB 2JIRA 1B13A 4YWMA 4AHXA 3MAQA 1S3SA 4D7ZB 3GTKA 5DYIA 2XJTA 1SMYD 2MX8A 4D3ZA 1T9OA 2Y0SA 3CF2A 2MX9A 1QYBA 1SMWA 2J9UB 3SJRA 1AA6A 4FGUA 1YV1A 2NAPA 4AONB 5AI3A 1IS1A 1A36A 1E8JA 2Z3QB 2C6AA 2E2IA 1T9QA 2CR8A 1PYUB 1R27A 1OGYA 4KDIA 1KQGA 1PT0A 2R92A 2CKCA 1Z92B 2R7ZA 4NOHA 2V0FA 5GAHc 2LTHA 1PPYA 2JIMA 2PMZA 1S24A 3GTOA 2K3NA 2A6ED 1A35A 2G6GA 2CKAA 3GTMA 4NOKA 2KKDA 1LKPA 2X0PA 2PI8A 4AR4A 3QWZA 1EK8A 1IU6A 3K57A 2ZIXA 4WFN1 1YNND 4FBSA 4AHWA 4U671 5JSBB 1LKOA 5T5MD 3VPBE 2RDVA 2DSXA 1PQEA 4E6YA 3ZG6A 2G5DA 1QDNA 4GS7D 4LHNA 1Y698 4IP9A 4FYDA 1WCMA 3LR2A 2C6BA 2JI3A 5DM61 4XGHA 4LMOA 2M4VA 1QCVA 1MIUA 2PPTA 1CAAA 5JVG1 5JVH1 5C1BA 4IP8A 1RWDA 1I50A 2MS3A 1UHEA 4AAYA 2AQLA 3PWFA 1PT1A 4AR3A 2H12A 3GTPA 4AN8A 4LHLA 1PYQA 1SFOA 2JA7A 5MLC3 4ZN3B 1DMRA 1FDIA 1RR8C 3GTJA 1TWHA 1R0HA 1E61A 4F3EA 1T8IA 2EEOB 1DVBA 3A44A 1KQFA 2LPIA 2NVXA 2N1DB 3CQZA 5MF6A 2C45A 3P2AA 2F4QA 4NOLA 2V45A 4O26A 4AHYA 1SEUA 1DD5A 1SMMA 2MQAA 1Y4ZA 2FIOA 2ERJA 2VPWA 3TIWA 4POGA 1CZ4A 4AI2A 3SS2A 3PZAA 1YK5A 1TMOA 2B63A 3FKIA 3B0AB 3PIP1 5IZ2A 1B2JA 2LKMB 1RDGA 4RV0A 3P8BA 4JLRC 1C09A 1G8KA 5DM71 2PJJA 5AI2A 4CEJA 1E60A 2A69D 1NXEA 2Z3RB 2JIPA 4KODA 1LTLA 2QL0A 2X0QA 4Q5GA 4JAGA 1UHDA 3HKZA 1G8JA 3ML1A 3IR7A 5IY0A 2ERSA 4KC6A 4QCLA 4AR5A 3DU6A 2PVXA 1BE7A 1BFYA 5EPPA 2FIPA 1K4SA 5MFZA 2E2HA 1TWCA 5C9HA 1TWGA 3U4QA 3RZ6A 3LPEB 1IRNA 1OWBA 4JAFA 2GMGA 1YLEA 2VPYA 3K59A 2PJHB 4V196 4CRYG 2M6OA 5GAEc 4KDLA 3IU3I 3DU5A 2LYIA 2M4YA 4L8IA 2NYDA 3QQCE 3IR6A 2R93A 7RXNA 3K5OA 1VZGA 5EINC 4KB4A 4Q5VA 1OWCA 2XJSA 2NYAA 3HU2A 2HR5A 3J7Y1 1CR5A 1NXGA 3KYVA 1RB9A 1NH3A 3WWLA 3CZBA 2K3OA 4AZDA 2AYJA 1IROA 1S2ZA 3KYXA 4AI1A 2B9SB 4AI3A 4FXDA 6RXNA 1FDOA 3B08B 5EIOC 2YU9A 1Y5IA 3K58A 5GAGc 1VC3B 1PQHA 5JSNB 2DMRA 3KYYA 4AYBA 3TM7B 2LCQA 3LR6A 4CEHA 1ZC1A 4B8CD 4KDDA 2VPXA 2VL6A 5GLFA 1R7RA 1Y1WA 4DMRA 4C2MA 1WLFA 1PQFA 2YUJA 1T9PA 2PNWA 4AI0A 4AHZA 2NVYA 2JI2A 1TGOA 3LHPS 1CADA 2VPZA 1JYBA 3QQ7A 1EU1A 5FTNA 1IW7D 4JADA 1YNJD 2BE5D 3KYUA 4UY81 1VZHA 3PKIA 4K9FA 1Y1VA 1I3QA 4D3YA 1Q16A 3MSUA 4AOKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E2H A;  2YU9 A;  1TWC A;  2A6E D;  1TWG A;  1TWA A;  2WB1 A;  4QIW A;  2A6H D;  1TWF A;  2JA6 A;  1WCM A;  3GTM A;  3GTJ A;  1TWH A;  4AYB A;  2VUM A;  1R9T A;  2A69 D;  2CW0 D;  1ZYR D;  2E2I A;  1HQM D;  1IW7 D;  3GTG A;  2NVX A;  1K83 A;  2WAQ A;  2O5J D;  3HKZ A;  1YNN D;  3CQZ A;  1I6V D;  2R92 A;  1YNJ D;  2A68 D;  2BE5 D;  2B63 A;  1Y1W A;  3GTK A;  2R93 A;  4C2M A;  3H0G A;  1Y1V A;  1SMY D;  2JA5 A;  1I3Q A;  3FKI A;  1I50 A;  3GTL A;  2R7Z A;  3GTQ A;  2Y0S A;  3GTP A;  2PMZ A;  1SFO A;  3GTO A;  2NVY A;  2JA7 A; 
#chains in the Genus database with same CATH topology
 1T6J A;  2EY4 E;  4KB2 A;  3K5L A;  1QQT A;  3PO3 L;  2KI8 A;  1Q8I A;  3QC8 A;  1GE9 A;  4AYB P;  1WC2 A;  4GA5 A;  2R92 L;  2GAE A;  1IU5 A;  3H97 A;  5AN9 H;  2X0O A;  1BRF A;  4ZM7 A;  5RXN A;  2PSM C;  1RYT A;  4A93 L;  2O5J D;  1AW8 B;  1PFV A;  3IR5 A;  1H5N A;  1RDV A;  2A68 D;  2N3E A;  4YWL A;  3KYL A;  2JA5 A;  5FTJ A;  3HU3 A;  2XJV A;  2IV2 X;  1YUX A;  5MLC 9;  3M3G A;  5H4U A;  3RZT A;  1RYQ A;  3WWN B;  2JI1 A;  5T5I D;  5FTL A;  4G6B A;  1E18 A;  2M6P A;  3QVD A;  2R4G A;  4H3T A;  1R9T A;  2HRO A;  2CW0 D;  1K4T A;  4JAE A;  1S30 A;  4POF A;  4V2R A;  3PIO 1;  3WVO A;  1EJ9 A;  4NOM A;  1BQ9 A;  2K2D A;  4JP6 A;  3K5N A;  3H3V M;  1YK4 A;  1H7V A;  2VK9 A;  4TPU A;  4OYD B;  2F5J A;  3DMR A;  4EJ3 A;  4ME3 A;  1DMS A;  1ISE A;  1TWF L;  2JIQ A;  4TVM A;  1VZI A;  1SMU A;  4KO8 A;  2AUS B;  1NNQ A;  4QIW A;  1R0J A;  2PYA A;  3J7Z 1;  3LWV B;  1F4L A;  1ODH A;  2EZA A;  3K5M A;  1T6P A;  4CS0 A;  3I4N L;  1ZYM A;  1LKM A;  2V3B B;  3LRD A;  5CQG A;  3K35 A;  1I50 L;  5K2M E;  1E32 A;  1K83 A;  3LF9 A;  3HKZ P;  2PIC A;  3GTP L;  1I6V D;  4XXB B;  3M4A A;  2B5I D;  3NFP I;  5MFP A;  3OUG A;  2APO B;  2JA7 L;  3H0G A;  1WJV A;  2Y0N A;  2KN9 A;  5H1S c;  1QCS A;  1TWH L;  3S15 L;  5DYG A;  1WQG A;  2XJU A;  1R0F A;  1CZ5 A;  2PVE A;  2XJQ A;  3PKJ A;  1PFU A;  4RXN A;  4BBS L;  2JIO A;  1TWA A;  1TWF A;  3LWP B;  1FHM A;  1OA9 A;  3MPS A;  5C44 L;  3RYG A;  2L0Z A;  4CEI A;  5MGN A;  4X6A L;  3X2I A;  4JJO A;  5M3M L;  2LPJ A;  1B2O A;  5GLX A;  3EZA A;  4C3J L;  2E2J L;  2AQC A;  3JR7 A;  2V3V A;  5FLM L;  1H0H A;  5C3E L;  2AE0 X;  1FHH A;  5IYC L;  3GTQ A;  2JA8 L;  3O5A A;  3HOX L;  5FTM A;  3HOZ L;  4QIW P;  5GAD c;  3X2G A;  2WB1 A;  3KYW A;  5FTK A;  1SC7 A;  3FDJ A;  2VUM A;  2B63 L;  2XJR A;  3S1N L;  1E5V A;  2V0E A;  1ZYR D;  4KAW X;  3GTG A;  1WQF A;  2K3Q A;  2WAQ A;  3SUM A;  3IAY A;  2XJP A;  1N10 A;  1A31 A;  4ZN1 B;  3S1Q L;  1BW4 A;  1R0G A;  3P9A A;  4GA6 A;  3EZB A;  3GTL A;  1DX8 A;  5C18 A;  8RXN A;  4AR6 A;  3QQ8 A;  1YUZ A;  4GFQ A;  1R5Z A;  3NZ4 A;  3PO2 L;  1ZRP A;  4KLN A;  1TL8 A;  1EH1 A;  4C3I L;  3HU1 A;  1R0I A;  1SIW A;  2E2I L;  5B6C A;  4AHC A;  2JA6 A;  3ENG A;  2A6H D;  1RRJ A;  4ENG A;  3U44 A;  4C5R A;  2E7Z A;  4BXX L;  3LNL A;  1WQH A;  1LPQ A;  3LWQ B;  4CRZ A;  1HQM D;  1V9M A;  1R49 A;  1B71 A;  3LR8 A;  1BQ8 A;  1VCX A;  3PLX B;  2JIR A;  1B13 A;  4YWM A;  4AHX A;  3MAQ A;  1S3S A;  4A3J L;  2R7Z L;  4A3L L;  4C5U A;  4D7Z B;  3GTK A;  2E2H L;  5DYI A;  3GTO L;  1TWC L;  2XJT A;  1SMY D;  2MX8 A;  4D3Z A;  1T9O A;  2Y0S A;  4BAB A;  3CF2 A;  2MX9 A;  1QYB A;  3RZD L;  3GTM L;  1SMW A;  2J9U B;  3SJR A;  3H9C A;  1AA6 A;  2WB1 P;  4BY7 L;  4FGU A;  1YV1 A;  2NAP A;  4AON B;  5AI3 A;  1IS1 A;  1I6H L;  1A36 A;  1E8J A;  4FFT A;  2Z3Q B;  2C6A A;  2E2I A;  1T9Q A;  2R93 L;  2CR8 A;  1PYU B;  2WAQ P;  1R27 A;  1OGY A;  4KDI A;  3H9B A;  1KQG A;  1PT0 A;  2R92 A;  2CKC A;  2RFK B;  3X2N A;  4FG4 A;  5FJ8 L;  1Z92 B;  2R7Z A;  4NOH A;  2V0F A;  5GAH c;  4A3F L;  1BW3 A;  1WCM L;  2LTH A;  1PPY A;  2JIM A;  2PMZ A;  1S24 A;  4C5S A;  3H99 A;  3GTO A;  2K3N A;  2A6E D;  1A35 A;  2NVT L;  2CKA A;  2G6G A;  3GTM A;  1EZB A;  3HJW B;  4NOK A;  4FG2 A;  2KKD A;  3M3Y L;  1LKP A;  2X0P A;  2PI8 A;  5IP9 L;  4AR4 A;  3QWZ A;  1EK8 A;  1IU6 A;  3K57 A;  2ZIX A;  4WFN 1;  1YNN D;  4FBS A;  4AHW A;  3RZO L;  3SUK A;  4U67 1;  1SFO L;  4BAA A;  5JSB B;  1LKO A;  5T5M D;  3VPB E;  2EZC A;  2RDV A;  2DSX A;  2NVQ L;  4E6Y A;  1PQE A;  3GTJ L;  3ZG6 A;  2G5D A;  1QDN A;  4GS7 D;  4LHN A;  1Y69 8;  2ENG A;  4IP9 A;  4FYD A;  1WCM A;  3LR2 A;  2C6B A;  2NVX L;  3X2K A;  2JI3 A;  3CQZ L;  1Y1W L;  5DM6 1;  4XGH A;  4JS7 A;  4LMO A;  2M4V A;  3S2H L;  1QCV A;  1MIU A;  2PPT A;  3HJY B;  1CAA A;  5JVG 1;  5JVH 1;  5C1B A;  4IP8 A;  3S2D L;  2NVY L;  1EZA A;  1RWD A;  2HVY C;  1I50 A;  2MS3 A;  1UHE A;  4AAY A;  2AQL A;  3PWF A;  1PT1 A;  4AR3 A;  2H12 A;  3GTP A;  4FER A;  4AN8 A;  4LHL A;  1PYQ A;  1SFO A;  2JA7 A;  2BH0 A;  5MLC 3;  4ZN3 B;  1DMR A;  1FDI A;  1RR8 C;  3GTJ A;  1TWH A;  1R0H A;  4BY1 L;  4F3E A;  3HOU L;  1E61 A;  1T8I A;  2YII A;  2EEO B;  1DVB A;  3A44 A;  1KQF A;  3I4M L;  2LPI A;  3HOY L;  2NVX A;  2N1D B;  3FKI L;  3K7A L;  1PZX A;  2KQA A;  4Y52 L;  3CQZ A;  5MF6 A;  2C45 A;  5M3F L;  3P2A A;  2F4Q A;  5M5X L;  4NOL A;  2V45 A;  3LWR B;  4O26 A;  3D30 A;  4AHY A;  1SEU A;  1DD5 A;  1SMM A;  2MQA A;  3HOV L;  3S16 L;  1Y4Z A;  2FIO A;  4A3E L;  2ERJ A;  2VPW A;  3TIW A;  3X2O A;  4POG A;  2JA5 L;  1CZ4 A;  4AI2 A;  3SS2 A;  3HAX C;  3PZA A;  1YK5 A;  1TMO A;  2B63 A;  4AVR A;  3S14 L;  2HCZ X;  3X2P A;  3FKI A;  1TWG L;  3B0A B;  3PIP 1;  5IZ2 A;  1B2J A;  2LKM B;  1RDG A;  4RV0 A;  3P8B A;  4JLR C;  1C09 A;  1G8K A;  5DM7 1;  2PJJ A;  4C2M 1;  5AI2 A;  4CEJ A;  3S17 L;  1E60 A;  2A69 D;  1NXE A;  2Z3R B;  2JIP A;  4KOD A;  1LTL A;  2QL0 A;  2X0Q A;  4Q5G A;  4JAG A;  1UHD A;  3X2M A;  3HKZ A;  1G8J A;  3ML1 A;  3IR7 A;  5IY0 A;  2ERS A;  4KC6 A;  4QCL A;  4AR5 A;  3DU6 A;  3X2J A;  2PVX A;  1BE7 A;  4Y7N L;  1BFY A;  1Y2M A;  2FIP A;  1K4S A;  5MFZ A;  5EPP A;  2E2H A;  1TWC A;  5C9H A;  1TWG A;  3U4Q A;  3RZ6 A;  3LPE B;  1IRN A;  1K83 L;  1OWB A;  4JAF A;  2GMG A;  5C4J L;  1YLE A;  2VPY A;  3K59 A;  2PJH B;  4V19 6;  4CRY G;  2M6O A;  3H0G L;  4A3K L;  5GAE c;  4A3G L;  4KDL A;  3EZE A;  3IU3 I;  3DU5 A;  2LYI A;  2M4Y A;  4L8I A;  4C3H L;  5C4X L;  2NYD A;  3QQC E;  3IR6 A;  2R93 A;  3M4O L;  2YU9 L;  7RXN A;  1TWA L;  2Y0S P;  3K5O A;  1VZG A;  5EIN C;  4KB4 A;  4Q5V A;  1W27 A;  1OWC A;  2XJS A;  2NYA A;  3HU2 A;  4CQ5 A;  2HR5 A;  3J7Y 1;  1CR5 A;  1NXG A;  3KYV A;  3LWO B;  4A3M L;  4L48 A;  4BBR L;  5GLY A;  1RB9 A;  1NH3 A;  3S1M L;  4C6G A;  3WWL A;  3GTQ L;  3CZB A;  2K3O A;  4AZD A;  3X2L A;  3PL5 A;  4JP7 A;  5GM9 A;  2AYJ A;  3X2H A;  1IRO A;  3SUJ A;  1S2Z A;  3KYX A;  4AI1 A;  4JCW A;  1PFW A;  1HD5 A;  4A3B L;  2B9S B;  4AI3 A;  4FXD A;  5IP7 L;  6RXN A;  3B08 B;  2VUM L;  1FDO A;  2PMZ P;  5EIO C;  2YU9 A;  1Y5I A;  3K58 A;  5GAG c;  1VC3 B;  3GTG L;  1PQH A;  5JSN B;  2DMR A;  3KYY A;  4AYB A;  3TM7 B;  2LCQ A;  3LR6 A;  4CEH A;  1ZC1 A;  4B8C D;  4KDD A;  2VPX A;  2VL6 A;  3SUL A;  5IYD L;  1Y1V L;  3GTL L;  1I3Q L;  2MP0 A;  4A3I L;  5GLF A;  1R7R A;  1Y1W A;  4DMR A;  4C2M A;  1WLF A;  1PQF A;  2JA6 L;  2YUJ A;  4A3C L;  1T9P A;  5M5Y L;  4A3D L;  2PNW A;  4AI0 A;  4AHZ A;  2NVY A;  1PFY A;  2JI2 A;  1TGO A;  3LHP S;  1CAD A;  1OA7 A;  2VPZ A;  1JYB A;  3QQ7 A;  1EU1 A;  1L8F A;  4V2Q A;  3S1R L;  1P7P A;  3GTK L;  2HWG A;  5IYB L;  5FTN A;  1IW7 D;  4JAD A;  3MQK B;  1YNJ D;  2BE5 D;  3KYU A;  4UY8 1;  1VZH A;  3PKI A;  4K9F A;  1Y1V A;  5M5W L;  1I3Q A;  3HOW L;  4D3Y A;  1Q16 A;  3MSU A;  4AOK B;  2EZB A;  1R9T L; 
#chains in the Genus database with same CATH homology
 4KB2 A;  3K5L A;  2KI8 A;  1Q8I A;  3QC8 A;  1GE9 A;  4GA5 A;  2GAE A;  1IU5 A;  5AN9 H;  2X0O A;  1BRF A;  5RXN A;  2PSM C;  1RYT A;  2O5J D;  1AW8 B;  3IR5 A;  1H5N A;  1RDV A;  2A68 D;  2N3E A;  4YWL A;  3KYL A;  2JA5 A;  5FTJ A;  3HU3 A;  2XJV A;  2IV2 X;  1YUX A;  5MLC 9;  3RZT A;  1RYQ A;  3WWN B;  2JI1 A;  5T5I D;  5FTL A;  4G6B A;  1E18 A;  2M6P A;  3QVD A;  2R4G A;  4H3T A;  1R9T A;  2CW0 D;  1K4T A;  4JAE A;  1S30 A;  4POF A;  3PIO 1;  3WVO A;  1EJ9 A;  4NOM A;  1BQ9 A;  2K2D A;  3K5N A;  1H7V A;  1YK4 A;  2VK9 A;  4TPU A;  4OYD B;  2F5J A;  3DMR A;  4EJ3 A;  4ME3 A;  1DMS A;  1ISE A;  2JIQ A;  4TVM A;  1VZI A;  1SMU A;  4KO8 A;  1NNQ A;  4QIW A;  1R0J A;  2PYA A;  3J7Z 1;  1ODH A;  3K5M A;  4CS0 A;  1LKM A;  2V3B B;  3LRD A;  5CQG A;  3K35 A;  5K2M E;  1E32 A;  1K83 A;  3LF9 A;  2PIC A;  1I6V D;  4XXB B;  3M4A A;  2B5I D;  3NFP I;  5MFP A;  3OUG A;  3H0G A;  1WJV A;  2Y0N A;  2KN9 A;  5H1S c;  1QCS A;  5DYG A;  1WQG A;  2XJU A;  1R0F A;  1CZ5 A;  2PVE A;  2XJQ A;  3PKJ A;  4RXN A;  2JIO A;  1TWA A;  1TWF A;  1FHM A;  3MPS A;  3RYG A;  2L0Z A;  4CEI A;  5MGN A;  2LPJ A;  1B2O A;  2V3V A;  1H0H A;  2AE0 X;  1FHH A;  3GTQ A;  3O5A A;  5FTM A;  5GAD c;  2WB1 A;  3KYW A;  5FTK A;  1SC7 A;  2VUM A;  2XJR A;  1E5V A;  2V0E A;  1ZYR D;  4KAW X;  3GTG A;  1WQF A;  2K3Q A;  2WAQ A;  3IAY A;  2XJP A;  1A31 A;  4ZN1 B;  1R0G A;  3P9A A;  4GA6 A;  3GTL A;  1DX8 A;  5C18 A;  8RXN A;  4AR6 A;  3QQ8 A;  1YUZ A;  4GFQ A;  1R5Z A;  1ZRP A;  4KLN A;  1TL8 A;  1EH1 A;  3HU1 A;  1R0I A;  1SIW A;  5B6C A;  4AHC A;  2JA6 A;  2A6H D;  1RRJ A;  3U44 A;  2E7Z A;  3LNL A;  1WQH A;  1LPQ A;  4CRZ A;  1HQM D;  1V9M A;  1R49 A;  1B71 A;  3LR8 A;  1BQ8 A;  1VCX A;  3PLX B;  2JIR A;  1B13 A;  4YWM A;  4AHX A;  3MAQ A;  1S3S A;  4D7Z B;  3GTK A;  5DYI A;  2XJT A;  1SMY D;  2MX8 A;  4D3Z A;  1T9O A;  2Y0S A;  3CF2 A;  2MX9 A;  1QYB A;  1SMW A;  2J9U B;  3SJR A;  1AA6 A;  4FGU A;  1YV1 A;  2NAP A;  4AON B;  5AI3 A;  1IS1 A;  1A36 A;  1E8J A;  2Z3Q B;  2C6A A;  2E2I A;  1T9Q A;  2CR8 A;  1PYU B;  1R27 A;  1OGY A;  4KDI A;  1KQG A;  1PT0 A;  2R92 A;  2CKC A;  1Z92 B;  2R7Z A;  4NOH A;  2V0F A;  5GAH c;  2LTH A;  1PPY A;  2JIM A;  2PMZ A;  1S24 A;  3GTO A;  2K3N A;  2A6E D;  1A35 A;  2G6G A;  2CKA A;  3GTM A;  4NOK A;  2KKD A;  1LKP A;  2X0P A;  2PI8 A;  4AR4 A;  3QWZ A;  1EK8 A;  1IU6 A;  3K57 A;  2ZIX A;  4WFN 1;  1YNN D;  4FBS A;  4AHW A;  4U67 1;  5JSB B;  1LKO A;  5T5M D;  3VPB E;  2RDV A;  2DSX A;  1PQE A;  4E6Y A;  3ZG6 A;  2G5D A;  1QDN A;  4GS7 D;  4LHN A;  1Y69 8;  4IP9 A;  4FYD A;  1WCM A;  3LR2 A;  2C6B A;  2JI3 A;  5DM6 1;  4XGH A;  4LMO A;  2M4V A;  1QCV A;  1MIU A;  2PPT A;  1CAA A;  5JVG 1;  5JVH 1;  5C1B A;  4IP8 A;  1RWD A;  1I50 A;  2MS3 A;  1UHE A;  4AAY A;  2AQL A;  3PWF A;  1PT1 A;  4AR3 A;  2H12 A;  3GTP A;  4AN8 A;  4LHL A;  1PYQ A;  1SFO A;  2JA7 A;  5MLC 3;  4ZN3 B;  1DMR A;  1FDI A;  1RR8 C;  3GTJ A;  1TWH A;  1R0H A;  1E61 A;  4F3E A;  1T8I A;  2EEO B;  1DVB A;  3A44 A;  1KQF A;  2LPI A;  2NVX A;  2N1D B;  3CQZ A;  5MF6 A;  2C45 A;  3P2A A;  2F4Q A;  4NOL A;  2V45 A;  4O26 A;  4AHY A;  1SEU A;  1DD5 A;  1SMM A;  2MQA A;  1Y4Z A;  2FIO A;  2ERJ A;  2VPW A;  3TIW A;  4POG A;  1CZ4 A;  4AI2 A;  3SS2 A;  3PZA A;  1YK5 A;  1TMO A;  2B63 A;  3FKI A;  3B0A B;  3PIP 1;  5IZ2 A;  1B2J A;  2LKM B;  1RDG A;  4RV0 A;  3P8B A;  4JLR C;  1C09 A;  1G8K A;  5DM7 1;  2PJJ A;  5AI2 A;  4CEJ A;  1E60 A;  2A69 D;  1NXE A;  2Z3R B;  2JIP A;  4KOD A;  1LTL A;  2QL0 A;  2X0Q A;  4Q5G A;  4JAG A;  1UHD A;  3HKZ A;  1G8J A;  3ML1 A;  3IR7 A;  5IY0 A;  2ERS A;  4KC6 A;  4QCL A;  4AR5 A;  3DU6 A;  2PVX A;  1BE7 A;  1BFY A;  5EPP A;  2FIP A;  1K4S A;  5MFZ A;  2E2H A;  1TWC A;  5C9H A;  1TWG A;  3U4Q A;  3RZ6 A;  3LPE B;  1IRN A;  1OWB A;  4JAF A;  2GMG A;  1YLE A;  2VPY A;  3K59 A;  2PJH B;  4V19 6;  4CRY G;  2M6O A;  5GAE c;  4KDL A;  3IU3 I;  3DU5 A;  2LYI A;  2M4Y A;  4L8I A;  2NYD A;  3QQC E;  3IR6 A;  2R93 A;  7RXN A;  3K5O A;  1VZG A;  5EIN C;  4KB4 A;  4Q5V A;  1OWC A;  2XJS A;  2NYA A;  3HU2 A;  2HR5 A;  3J7Y 1;  1CR5 A;  1NXG A;  3KYV A;  1RB9 A;  1NH3 A;  3WWL A;  3CZB A;  2K3O A;  4AZD A;  2AYJ A;  1IRO A;  1S2Z A;  3KYX A;  4AI1 A;  2B9S B;  4AI3 A;  4FXD A;  6RXN A;  1FDO A;  3B08 B;  5EIO C;  2YU9 A;  1Y5I A;  3K58 A;  5GAG c;  1VC3 B;  1PQH A;  5JSN B;  2DMR A;  3KYY A;  4AYB A;  3TM7 B;  2LCQ A;  3LR6 A;  4CEH A;  1ZC1 A;  4B8C D;  4KDD A;  2VPX A;  2VL6 A;  5GLF A;  1R7R A;  1Y1W A;  4DMR A;  4C2M A;  1WLF A;  1PQF A;  2YUJ A;  1T9P A;  2PNW A;  4AI0 A;  4AHZ A;  2NVY A;  2JI2 A;  1TGO A;  3LHP S;  1CAD A;  2VPZ A;  1JYB A;  3QQ7 A;  1EU1 A;  5FTN A;  1IW7 D;  4JAD A;  1YNJ D;  2BE5 D;  3KYU A;  4UY8 1;  1VZH A;  3PKI A;  4K9F A;  1Y1V A;  1I3Q A;  4D3Y A;  1Q16 A;  3MSU A;  4AOK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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