2O5JD

Crystal structure of the t. thermophilus rnap polymerase elongation complex with the ntp substrate analog
Total Genus 275
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
275
sequence length
1504
structure length
1264
Chain Sequence
KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGAADITQGLPRVIELFEARRPKAKAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEAVEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for substrate loading in bacterial RNA polymerase.
pubmed doi rcsb
molecule tags Transferase/dna-rna hybrid
molecule keywords 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP
total genus 275
structure length 1264
sequence length 1504
chains with identical sequence N
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2006-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00623 RNA_pol_Rpb1_2 RNA polymerase Rpb1, domain 2
D PF04983 RNA_pol_Rpb1_3 RNA polymerase Rpb1, domain 3
D PF04997 RNA_pol_Rpb1_1 RNA polymerase Rpb1, domain 1
D PF04998 RNA_pol_Rpb1_5 RNA polymerase Rpb1, domain 5
D PF05000 RNA_pol_Rpb1_4 RNA polymerase Rpb1, domain 4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.30 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 2o5jD05
1.10.274.100 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Enzyme I; Chain A, domain 2 2o5jD04
2.20.28.170 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2o5jD07
2.40.40.70 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2o5jD03
2R93A 1I50A 2VUMA 1HQMD 1WCMA 2YU9A 2BE5D 2A68D 2A6ED 2A69D 1I6VD 3GTLA 2NVYA 3GTMA 2WB1A 3HKZA 4QIWA 1ZYRD 2CW0D 3GTOA 1TWAA 1YNJD 1SFOA 3GTKA 4C2MA 2NVXA 2WAQA 1IW7D 1SMYD 1Y1WA 3GTQA 2JA7A 3H0GA 3GTGA 1TWGA 1R9TA 2Y0SA 4AYBA 2JA5A 2R7ZA 2E2IA 3GTJA 3GTPA 2JA6A 2A6HD 1K83A 1YNND 1TWFA 1Y1VA 3CQZA 2B63A 2O5JD 1TWHA 1I3QA 2R92A 2E2HA 2PMZA 1TWCA 3FKIA
chains in the Genus database with same CATH superfamily
2K3QA 4XXBB 3HKZP 3S16L 3P8BA 2R92L 4FERA 2A69D 3U4QA 1T9QA 1I50L 2WB1A 1VC3B 2HCZX 5K2ME 4Y52L 2JI3A 5GAHc 3S2DL 1DMRA 1S3SA 4RXNA 4C3JL 4Y7NL 3A44A 1LKPA 3MAQA 4BABA 3DMRA 2JIQA 3QC8A 1IROA 1DD5A 1YUZA 3K7AL 2VL6A 4YWLA 1TWFA 1GE9A 5DYGA 1T9OA 4EJ3A 4A3GL 4BY7L 4A3IL 1I3QA 2KI8A 1TWCA 2FIOA 4JAGA 2APOB 4QIWP 2YU9A 1OWCA 3X2LA 1BE7A 8RXNA 3GTLA 4FYDA 1RYQA 2K3NA 2J9UB 3K57A 6RXNA 1Y5IA 1E5VA 5JSBB 4CQ5A 4JAEA 1YUXA 1R9TA 3LRDA 1Y1WL 1W27A 2GAEA 1NXGA 5C44L 1Y2MA 1OA7A 4H3TA 2VPXA 4KODA 2R7ZL 4C5RA 2LKMB 4O26A 4AHZA 4QCLA 3SS2A 2A6ED 4A3KL 3WWNB 4FG2A 3MPSA 1K4TA 1R27A 2YU9L 1SMWA 4AYBP 1TGOA 3TM7B 1ZYRD 2CW0D 1SC7A 2E7ZA 3GTML 1RDVA 5JVG1 2LTHA 3HOWL 3H0GA 5IYDL 2MP0A 2AQCA 1T8IA 2KQAA 4AHXA 4AONB 5C4XL 5T5ID 3GTJL 4FXDA 1R7RA 3CQZL 4AN8A 7RXNA 3X2NA 2KKDA 5GLFA 1PYQA 3I4NL 1YK5A 1EJ9A 1IU5A 5FJ8L 3LWPB 2PICA 2CKCA 4BXXL 3U44A 4A3DL 2FIPA 1VZGA 2LYIA 2WAQA 3K5OA 1N10A 3B08B 1Q8IA 3P9AA 5MLC3 2NVXL 3VPBE 1JYBA 3HU1A 1B71A 2MX8A 1A35A 4KB2A 2EZBA 5EINC 1FDIA 1LTLA 5IZ2A 1T9PA 1Y1VA 5MF6A 3PIP1 1G8KA 2R92A 2X0OA 1RDGA 1PFUA 2PMZA 4G6BA 3EZEA 3PIO1 2XJPA 1CADA 3X2KA 5RXNA 2WB1P 1I6HL 3O5AA 4CEHA 1S2ZA 3HOVL 1PT1A 3KYYA 1LKOA 3H9CA 5C1BA 2M6OA 5FTJA 4JP7A 3QVDA 4GA5A 3I4ML 4U671 1ZRPA 5H4UA 1YNJD 1SEUA 4LHLA 5C18A 2LPJA 2NVYL 2VPWA 5IY0A 1YK4A 1E18A 5DM61 5IYBL 4L8IA 3QQ7A 2JIRA 4GS7D 3MQKB 2E2IL 1RWDA 1B2OA 5EPPA 1NH3A 4AI1A 2ENGA 4JAFA 2B63L 1DVBA 1IU6A 1Z92B 3LHPS 3PKIA 1A36A 2VPYA 3OUGA 2JI1A 1SIWA 1DMSA 4C5UA 2PVEA 5M3FL 4POFA 4CEJA 1Y1WA 5FLML 2RFKB 1R0HA 1PYUB 3GTGA 3H9BA 2ZIXA 4AHWA 5AN9H 2M6PA 2Y0SA 4CS0A 1FDOA 3SUJA 4F3EA 5IYCL 2HROA 5H1Sc 2R7ZA 1PQEA 1AA6A 2XJSA 2V45A 3X2IA 4LHNA 1PQHA 4ZN3B 3S15L 4NOKA 3S14L 5AI3A 1Y4ZA 1R0GA 1KQFA 5M3ML 2NYAA 1RRJA 4D3YA 3WVOA 4TPUA 1WLFA 3EZAA 3PL5A 4FG4A 3KYVA 3DU6A 4IP8A 2V3BB 2NAPA 3GTMA 1SFOA 2PSMC 1PQFA 3QQCE 1FHHA 4AI0A 3FDJA 2PVXA 5MFPA 2F5JA 1EH1A 3GTJA 1EK8A 3LWVB 3GTGL 5FTNA 2K2DA 2B9SB 3CQZA 2M4VA 2JA6L 1S24A 1BRFA 3FKIA 2GMGA 5FTMA 4LMOA 2X0PA 1WC2A 1TWHL 1IRNA 2E2HL 3CZBA 1WQHA 2ERJA 3H99A 3H97A 2WAQP 5GAEc 5IP9L 4AOKB 4KLNA 1EU1A 4JLRC 1WQGA 2NVXA 3X2GA 1WJVA 4A93L 4AZDA 2XJTA 2Z3QB 4UY81 3CF2A 1T6JA 1OA9A 2XJRA 1K4SA 1RB9A 3PZAA 1SFOL 4X6AL 3RZTA 3GTQL 2PMZP 3KYWA 1R0FA 3S1QL 3MSUA 1DX8A 5DYIA 5M5WL 4AI2A 2JA5L 1SMUA 3X2HA 4B8CD 3QQ8A 2R4GA 4C6GA 5GADc 2DMRA 1E8JA 5FTLA 1ZYMA 4Q5VA 3FKIL 1MIUA 2Z3RB 4TVMA 4NOHA 2NVYA 2JIPA 3PLXB 2XJUA 3M3YL 4V2QA 1TWAL 3GTKL 3RZDL 2PJJA 1T6PA 1SMMA 1TL8A 2E2IA 1P7PA 1WQFA 5MLC9 3NZ4A 3SJRA 1YNND 5M5YL 2HR5A 2PNWA 3X2PA 2B63A 4ZM7A 1CAAA 3LWRB 1TMOA 2CR8A 3HU2A 4FGUA 1YLEA 2N1DB 4DMRA 4NOLA 4KC6A 2V3VA 4Q5GA 5M5XL 1IS1A 2HVYC 1HQMD 4FFTA 2BE5D 3B0AB 3M4OL 1VZHA 2NVQL 3HOYL 2PJHB 1FHMA 3GTOA 2PPTA 1IW7D 1R0JA 2NYDA 1V9MA 3RZ6A 3ENGA 1A31A 1CZ5A 4AYBA 3PO2L 5C4JL 5DM71 4JP6A 2JIOA 3LR6A 4A3EL 2KN9A 1ISEA 3IR5A 2MS3A 2R93A 3RYGA 4GA6A 2EEOB 1KQGA 1HD5A 4NOMA 3D30A 3S1ML 4POGA 4L48A 4AI3A 1QCSA 1BW3A 3IU3I 1BQ9A 2ERSA 2EY4E 4C2MA 1E61A 1PT0A 1B2JA 1B13A 4C3HL 1R0IA 1F4LA 1PZXA 3P2AA 4AR6A 3GTOL 1PFWA 4V2RA 5GLXA 4KDDA 2JA6A 1UHDA 1EZAA 1TWGL 1E32A 4C3IL 2BH0A 1NXEA 1TWHA 2E2HA 3HOXL 3HU3A 3IR6A 5B6CA 3S1NL 3LR2A 1ODHA 2JA8L 2DSXA 2L0ZA 4AR3A 3HJWB 4WFN1 1ZC1A 1PFYA 2B5ID 3LR8A 2C6AA 4BBRL 1I6VD 2R93L 1WCML 3PKJA 2NVTL 2QL0A 1SMYD 1R49A 3GTQA 5CQGA 4ENGA 3HJYB 2JA5A 2JA7L 1LPQA 4V196 2AYJA 2V0EA 3SUMA 1R5ZA 2AUSB 2C45A 1Y698 3GTPL 1K83L 2VPZA 2K3OA 1Q16A 4YWMA 2XJVA 5GLYA 1BW4A 1EZBA 3K59A 2VUMA 1S30A 3X2OA 3DU5A 3J7Z1 1YV1A 2PI8A 1H5NA 1OGYA 5C9HA 4D7ZB 2XJQA 5GM9A 4GFQA 2PYAA 1QDNA 4BAAA 3HKZA 2EZAA 3S2HL 4A3LL 1TWAA 3GTKA 4IP9A 4AR4A 5IP7L 3HOZL 5AI2A 4A3ML 4JCWA 3QWZA 1QYBA 4C2M1 2N3EA 3KYXA 4RV0A 3ZG6A 2G6GA 4AAYA 1L8FA 3H3VM 3K35A 3TIWA 4K9FA 1QQTA 1TWFL 4AHCA 4KB4A 2C6BA 4CRYG 4KDLA 3NFPI 3J7Y1 4A3JL 3HAXC 1CZ4A 1I3QL 5MGNA 5JVH1 1TWCL 1G8JA 2A68D 2JIMA 3SULA 4BBSL 3M3GA 4D3ZA 2VUML 1H0HA 4QIWA 3LWOB 3GTLL 3K5LA 2LCQA 2VK9A 4OYDB 3PWFA 1R9TL 4FBSA 3X2MA 2O5JD 2IV2X 3K58A 4KDIA 2EZCA 2LPIA 2M4YA 1PPYA 1VCXA 1PFVA 3X2JA 4AVRA 3K5NA 2CKAA 3PO3L 3IR7A 5C3EL 1C09A 4A3BL 3LPEB 2AE0X 2H12A 4JS7A 3SUKA 2Y0SP 4C5SA 4A3CL 1RR8C 2MQAA 4ZN1B 2X0QA 4A3FL 1CR5A 1TWGA 4XGHA 3K5MA 2MX9A 4AHYA 1RYTA 4E6YA 3H0GL 4ME3A 2AQLA 3S17L 2G5DA 1OWBA 3LWQB 2V0FA 3JR7A 2JI2A 1BFYA 3ML1A 1I50A 1NNQA 2F4QA 1WCMA 3M4AA 3IAYA 1AW8B 2Y0NA 4JADA 4JJOA 5GAGc 3LF9A 1VZIA 4AR5A 2HWGA 2YUJA 4BY1L 3KYLA 1BQ8A 3HOUL 4KO8A 2JA7A 5T5MD 1H7VA 5MFZA 3LNLA 1QCVA 3EZBA 4KAWX 3KYUA 2RDVA 3RZOL 3GTPA 3WWLA 3S1RL 1UHEA 2A6HD 1K83A 1LKMA 4CEIA 2YIIA 2E2JL 1E60A 5EIOC 1Y1VL 4CRZA 5FTKA 5JSNB
chains in the Genus database with same CATH topology
2K3QA 4XXBB 3P8BA 2A69D 3U4QA 1T9QA 2WB1A 1VC3B 5K2ME 2JI3A 5GAHc 1DMRA 1S3SA 4RXNA 3A44A 1LKPA 3MAQA 3DMRA 2JIQA 3QC8A 1IROA 1DD5A 1YUZA 4YWLA 2VL6A 5DYGA 1TWFA 1GE9A 1T9OA 4EJ3A 1I3QA 2KI8A 1TWCA 2FIOA 4JAGA 2YU9A 1OWCA 1BE7A 8RXNA 3GTLA 4FYDA 1RYQA 2K3NA 2J9UB 3K57A 6RXNA 1Y5IA 1E5VA 5JSBB 4JAEA 1YUXA 1R9TA 3LRDA 2GAEA 1NXGA 4H3TA 2VPXA 4KODA 2LKMB 4O26A 4AHZA 4QCLA 3SS2A 2A6ED 3WWNB 3MPSA 1K4TA 1R27A 1SMWA 3TM7B 1TGOA 1ZYRD 2CW0D 1SC7A 2E7ZA 1RDVA 5JVG1 2LTHA 3H0GA 1T8IA 4AHXA 4AONB 5T5ID 4FXDA 1R7RA 4AN8A 7RXNA 2KKDA 5GLFA 1PYQA 1YK5A 1EJ9A 1IU5A 2PICA 2CKCA 3U44A 2FIPA 1VZGA 2LYIA 2WAQA 3K5OA 3B08B 1Q8IA 3P9AA 5MLC3 3VPBE 1JYBA 3HU1A 1B71A 2MX8A 1A35A 4KB2A 5EINC 1FDIA 1LTLA 5IZ2A 1T9PA 1Y1VA 5MF6A 3PIP1 1G8KA 2R92A 2X0OA 1RDGA 4G6BA 2PMZA 3PIO1 2XJPA 1CADA 5RXNA 3O5AA 4CEHA 1S2ZA 1PT1A 3KYYA 1LKOA 5C1BA 2M6OA 5FTJA 3QVDA 4GA5A 4U671 1ZRPA 1YNJD 1SEUA 4LHLA 5C18A 2LPJA 2VPWA 5IY0A 1YK4A 1E18A 5DM61 4L8IA 3QQ7A 2JIRA 4GS7D 1RWDA 1B2OA 5EPPA 1NH3A 4AI1A 4JAFA 1DVBA 1IU6A 1Z92B 3LHPS 3PKIA 1A36A 2VPYA 3OUGA 2JI1A 1SIWA 1DMSA 2PVEA 4POFA 4CEJA 1Y1WA 1R0HA 1PYUB 3GTGA 2ZIXA 4AHWA 5AN9H 2M6PA 2Y0SA 4CS0A 1FDOA 4F3EA 5H1Sc 1PQEA 2R7ZA 1AA6A 2XJSA 2V45A 4LHNA 1PQHA 4ZN3B 1Y4ZA 4NOKA 5AI3A 1R0GA 1KQFA 2NYAA 1RRJA 4D3YA 3WVOA 4TPUA 1WLFA 3KYVA 3DU6A 4IP8A 2V3BB 2NAPA 3GTMA 1SFOA 2PSMC 1PQFA 3QQCE 1FHHA 4AI0A 2PVXA 5MFPA 2F5JA 1EH1A 3GTJA 1EK8A 5FTNA 2K2DA 2B9SB 3CQZA 2M4VA 1S24A 1BRFA 3FKIA 2GMGA 5FTMA 4LMOA 2X0PA 1IRNA 3CZBA 1WQHA 2ERJA 5GAEc 4AOKB 4KLNA 1EU1A 4JLRC 1WQGA 2NVXA 1WJVA 4AZDA 2XJTA 2Z3QB 4UY81 3CF2A 2XJRA 3PZAA 1K4SA 1RB9A 1DX8A 3RZTA 1R0FA 3KYWA 3MSUA 5DYIA 4AI2A 1SMUA 4B8CD 3QQ8A 2R4GA 5GADc 2DMRA 1E8JA 5FTLA 4Q5VA 1MIUA 2Z3RB 4TVMA 4NOHA 2NVYA 2JIPA 3PLXB 2XJUA 2PJJA 1SMMA 1TL8A 2E2IA 1WQFA 5MLC9 3SJRA 1YNND 2HR5A 2PNWA 2B63A 1CAAA 1TMOA 2CR8A 3HU2A 4FGUA 1YLEA 2N1DB 4DMRA 4NOLA 4KC6A 2V3VA 4Q5GA 1IS1A 1HQMD 2BE5D 3B0AB 1VZHA 2PJHB 1FHMA 3GTOA 2PPTA 1IW7D 1R0JA 2NYDA 1V9MA 3RZ6A 1A31A 1CZ5A 4AYBA 5DM71 2JIOA 3LR6A 2KN9A 1ISEA 3IR5A 2MS3A 2R93A 3RYGA 4GA6A 2EEOB 1KQGA 4NOMA 4POGA 4AI3A 1QCSA 3IU3I 1BQ9A 2ERSA 4C2MA 1E61A 1PT0A 1B2JA 1B13A 1R0IA 3P2AA 4AR6A 4KDDA 2JA6A 1UHDA 1E32A 1NXEA 1TWHA 2E2HA 3HU3A 3IR6A 5B6CA 3LR2A 1ODHA 2DSXA 2L0ZA 4AR3A 4WFN1 1ZC1A 2B5ID 3LR8A 2C6AA 1I6VD 3PKJA 2QL0A 1SMYD 1R49A 3GTQA 5CQGA 2JA5A 1LPQA 4V196 2AYJA 2V0EA 1R5ZA 2C45A 1Y698 2VPZA 2K3OA 1Q16A 4YWMA 2XJVA 3K59A 2VUMA 1S30A 3DU5A 3J7Z1 1YV1A 2PI8A 1H5NA 1OGYA 5C9HA 4D7ZB 2XJQA 4GFQA 2PYAA 1QDNA 3HKZA 1TWAA 3GTKA 4IP9A 4AR4A 5AI2A 3QWZA 1QYBA 2N3EA 3KYXA 4RV0A 3ZG6A 2G6GA 4AAYA 3K35A 3TIWA 4K9FA 4AHCA 4KB4A 2C6BA 4CRYG 4KDLA 3NFPI 3J7Y1 1CZ4A 5MGNA 5JVH1 1G8JA 2A68D 2JIMA 4D3ZA 1H0HA 4QIWA 3K5LA 2LCQA 2VK9A 4OYDB 3PWFA 4FBSA 2O5JD 2IV2X 3K58A 4KDIA 2LPIA 2M4YA 1PPYA 1VCXA 3K5NA 2CKAA 3IR7A 1C09A 3LPEB 2AE0X 2H12A 1RR8C 2MQAA 4ZN1B 2X0QA 1CR5A 1TWGA 4XGHA 3K5MA 2MX9A 4AHYA 1RYTA 4E6YA 4ME3A 2AQLA 2G5DA 1OWBA 2V0FA 2JI2A 1BFYA 3ML1A 1I50A 1NNQA 2F4QA 1WCMA 3M4AA 3IAYA 1AW8B 2Y0NA 4JADA 5GAGc 3LF9A 1VZIA 4AR5A 2YUJA 3KYLA 1BQ8A 4KO8A 5T5MD 2JA7A 1H7VA 5MFZA 3LNLA 1QCVA 4KAWX 3KYUA 2RDVA 1UHEA 3GTPA 3WWLA 2A6HD 1K83A 1LKMA 4CEIA 1E60A 5EIOC 4CRZA 5FTKA 5JSNB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R93 A;  1I50 A;  2VUM A;  1HQM D;  1WCM A;  2YU9 A;  2BE5 D;  2A68 D;  2A6E D;  2A69 D;  1I6V D;  3GTL A;  2NVY A;  3GTM A;  2WB1 A;  3HKZ A;  4QIW A;  1ZYR D;  2CW0 D;  3GTO A;  1TWA A;  1YNJ D;  1SFO A;  3GTK A;  4C2M A;  2NVX A;  2WAQ A;  1IW7 D;  1SMY D;  1Y1W A;  3GTQ A;  2JA7 A;  3H0G A;  3GTG A;  1TWG A;  1R9T A;  2Y0S A;  4AYB A;  2JA5 A;  2R7Z A;  2E2I A;  3GTJ A;  3GTP A;  2JA6 A;  2A6H D;  1K83 A;  1YNN D;  1TWF A;  1Y1V A;  3CQZ A;  2B63 A;  2O5J D;  1TWH A;  1I3Q A;  2R92 A;  2E2H A;  2PMZ A;  1TWC A;  3FKI A; 
#chains in the Genus database with same CATH topology
 2K3Q A;  4XXB B;  3HKZ P;  3S16 L;  3P8B A;  2R92 L;  4FER A;  2A69 D;  3U4Q A;  1T9Q A;  1I50 L;  2WB1 A;  1VC3 B;  2HCZ X;  5K2M E;  4Y52 L;  2JI3 A;  5GAH c;  3S2D L;  1DMR A;  1S3S A;  4RXN A;  4C3J L;  4Y7N L;  3A44 A;  1LKP A;  3MAQ A;  4BAB A;  3DMR A;  2JIQ A;  3QC8 A;  1IRO A;  1DD5 A;  1YUZ A;  3K7A L;  2VL6 A;  4YWL A;  1TWF A;  1GE9 A;  5DYG A;  1T9O A;  4EJ3 A;  4A3G L;  4BY7 L;  4A3I L;  1I3Q A;  2KI8 A;  1TWC A;  2FIO A;  4JAG A;  2APO B;  4QIW P;  2YU9 A;  1OWC A;  3X2L A;  1BE7 A;  8RXN A;  3GTL A;  4FYD A;  1RYQ A;  2K3N A;  2J9U B;  3K57 A;  6RXN A;  1Y5I A;  1E5V A;  5JSB B;  4CQ5 A;  4JAE A;  1YUX A;  1R9T A;  3LRD A;  1Y1W L;  1W27 A;  2GAE A;  1NXG A;  5C44 L;  1Y2M A;  1OA7 A;  4H3T A;  2VPX A;  4KOD A;  2R7Z L;  4C5R A;  2LKM B;  4O26 A;  4AHZ A;  4QCL A;  3SS2 A;  2A6E D;  4A3K L;  3WWN B;  4FG2 A;  3MPS A;  1K4T A;  1R27 A;  2YU9 L;  1SMW A;  4AYB P;  1TGO A;  3TM7 B;  1ZYR D;  2CW0 D;  1SC7 A;  2E7Z A;  3GTM L;  1RDV A;  5JVG 1;  2LTH A;  3HOW L;  3H0G A;  5IYD L;  2MP0 A;  2AQC A;  1T8I A;  2KQA A;  4AHX A;  4AON B;  5C4X L;  5T5I D;  3GTJ L;  4FXD A;  1R7R A;  3CQZ L;  4AN8 A;  7RXN A;  3X2N A;  2KKD A;  5GLF A;  1PYQ A;  3I4N L;  1YK5 A;  1EJ9 A;  1IU5 A;  5FJ8 L;  3LWP B;  2PIC A;  2CKC A;  4BXX L;  3U44 A;  4A3D L;  2FIP A;  1VZG A;  2LYI A;  2WAQ A;  3K5O A;  1N10 A;  3B08 B;  1Q8I A;  3P9A A;  5MLC 3;  2NVX L;  3VPB E;  1JYB A;  3HU1 A;  1B71 A;  2MX8 A;  1A35 A;  4KB2 A;  2EZB A;  5EIN C;  1FDI A;  1LTL A;  5IZ2 A;  1T9P A;  1Y1V A;  5MF6 A;  3PIP 1;  1G8K A;  2R92 A;  2X0O A;  1RDG A;  1PFU A;  2PMZ A;  4G6B A;  3EZE A;  3PIO 1;  2XJP A;  1CAD A;  3X2K A;  5RXN A;  2WB1 P;  1I6H L;  3O5A A;  4CEH A;  1S2Z A;  3HOV L;  1PT1 A;  3KYY A;  1LKO A;  3H9C A;  5C1B A;  2M6O A;  5FTJ A;  4JP7 A;  3QVD A;  4GA5 A;  3I4M L;  4U67 1;  1ZRP A;  5H4U A;  1YNJ D;  1SEU A;  4LHL A;  5C18 A;  2LPJ A;  2NVY L;  2VPW A;  5IY0 A;  1YK4 A;  1E18 A;  5DM6 1;  5IYB L;  4L8I A;  3QQ7 A;  2JIR A;  4GS7 D;  3MQK B;  2E2I L;  1RWD A;  1B2O A;  5EPP A;  1NH3 A;  4AI1 A;  2ENG A;  4JAF A;  2B63 L;  1DVB A;  1IU6 A;  1Z92 B;  3LHP S;  3PKI A;  1A36 A;  2VPY A;  3OUG A;  2JI1 A;  1SIW A;  1DMS A;  4C5U A;  2PVE A;  5M3F L;  4POF A;  4CEJ A;  1Y1W A;  5FLM L;  2RFK B;  1R0H A;  1PYU B;  3GTG A;  3H9B A;  2ZIX A;  4AHW A;  5AN9 H;  2M6P A;  2Y0S A;  4CS0 A;  1FDO A;  3SUJ A;  4F3E A;  5IYC L;  2HRO A;  5H1S c;  2R7Z A;  1PQE A;  1AA6 A;  2XJS A;  2V45 A;  3X2I A;  4LHN A;  1PQH A;  4ZN3 B;  3S15 L;  4NOK A;  3S14 L;  5AI3 A;  1Y4Z A;  1R0G A;  1KQF A;  5M3M L;  2NYA A;  1RRJ A;  4D3Y A;  3WVO A;  4TPU A;  1WLF A;  3EZA A;  3PL5 A;  4FG4 A;  3KYV A;  3DU6 A;  4IP8 A;  2V3B B;  2NAP A;  3GTM A;  1SFO A;  2PSM C;  1PQF A;  3QQC E;  1FHH A;  4AI0 A;  3FDJ A;  2PVX A;  5MFP A;  2F5J A;  1EH1 A;  3GTJ A;  1EK8 A;  3LWV B;  3GTG L;  5FTN A;  2K2D A;  2B9S B;  3CQZ A;  2M4V A;  2JA6 L;  1S24 A;  1BRF A;  3FKI A;  2GMG A;  5FTM A;  4LMO A;  2X0P A;  1WC2 A;  1TWH L;  1IRN A;  2E2H L;  3CZB A;  1WQH A;  2ERJ A;  3H99 A;  3H97 A;  2WAQ P;  5GAE c;  5IP9 L;  4AOK B;  4KLN A;  1EU1 A;  4JLR C;  1WQG A;  2NVX A;  3X2G A;  1WJV A;  4A93 L;  4AZD A;  2XJT A;  2Z3Q B;  4UY8 1;  3CF2 A;  1T6J A;  1OA9 A;  2XJR A;  1K4S A;  1RB9 A;  3PZA A;  1SFO L;  4X6A L;  3RZT A;  3GTQ L;  2PMZ P;  3KYW A;  1R0F A;  3S1Q L;  3MSU A;  1DX8 A;  5DYI A;  5M5W L;  4AI2 A;  2JA5 L;  1SMU A;  3X2H A;  4B8C D;  3QQ8 A;  2R4G A;  4C6G A;  5GAD c;  2DMR A;  1E8J A;  5FTL A;  1ZYM A;  4Q5V A;  3FKI L;  1MIU A;  2Z3R B;  4TVM A;  4NOH A;  2NVY A;  2JIP A;  3PLX B;  2XJU A;  3M3Y L;  4V2Q A;  1TWA L;  3GTK L;  3RZD L;  2PJJ A;  1T6P A;  1SMM A;  1TL8 A;  2E2I A;  1P7P A;  1WQF A;  5MLC 9;  3NZ4 A;  3SJR A;  1YNN D;  5M5Y L;  2HR5 A;  2PNW A;  3X2P A;  2B63 A;  4ZM7 A;  1CAA A;  3LWR B;  1TMO A;  2CR8 A;  3HU2 A;  4FGU A;  1YLE A;  2N1D B;  4DMR A;  4NOL A;  4KC6 A;  2V3V A;  4Q5G A;  5M5X L;  1IS1 A;  2HVY C;  1HQM D;  4FFT A;  2BE5 D;  3B0A B;  3M4O L;  1VZH A;  2NVQ L;  3HOY L;  2PJH B;  1FHM A;  3GTO A;  2PPT A;  1IW7 D;  1R0J A;  2NYD A;  1V9M A;  3RZ6 A;  3ENG A;  1A31 A;  1CZ5 A;  4AYB A;  3PO2 L;  5C4J L;  5DM7 1;  4JP6 A;  2JIO A;  3LR6 A;  4A3E L;  2KN9 A;  1ISE A;  3IR5 A;  2MS3 A;  2R93 A;  3RYG A;  4GA6 A;  2EEO B;  1KQG A;  1HD5 A;  4NOM A;  3D30 A;  3S1M L;  4POG A;  4L48 A;  4AI3 A;  1QCS A;  1BW3 A;  3IU3 I;  1BQ9 A;  2ERS A;  2EY4 E;  4C2M A;  1E61 A;  1PT0 A;  1B2J A;  1B13 A;  4C3H L;  1R0I A;  1F4L A;  1PZX A;  3P2A A;  4AR6 A;  3GTO L;  1PFW A;  4V2R A;  5GLX A;  4KDD A;  2JA6 A;  1UHD A;  1EZA A;  1TWG L;  1E32 A;  4C3I L;  2BH0 A;  1NXE A;  1TWH A;  2E2H A;  3HOX L;  3HU3 A;  3IR6 A;  5B6C A;  3S1N L;  3LR2 A;  1ODH A;  2JA8 L;  2DSX A;  2L0Z A;  4AR3 A;  3HJW B;  4WFN 1;  1ZC1 A;  1PFY A;  2B5I D;  3LR8 A;  2C6A A;  4BBR L;  1I6V D;  2R93 L;  1WCM L;  3PKJ A;  2NVT L;  2QL0 A;  1SMY D;  1R49 A;  3GTQ A;  5CQG A;  4ENG A;  3HJY B;  2JA5 A;  2JA7 L;  1LPQ A;  4V19 6;  2AYJ A;  2V0E A;  3SUM A;  1R5Z A;  2AUS B;  2C45 A;  1Y69 8;  3GTP L;  1K83 L;  2VPZ A;  2K3O A;  1Q16 A;  4YWM A;  2XJV A;  5GLY A;  1BW4 A;  1EZB A;  3K59 A;  2VUM A;  1S30 A;  3X2O A;  3DU5 A;  3J7Z 1;  1YV1 A;  2PI8 A;  1H5N A;  1OGY A;  5C9H A;  4D7Z B;  2XJQ A;  5GM9 A;  4GFQ A;  2PYA A;  1QDN A;  4BAA A;  3HKZ A;  2EZA A;  3S2H L;  4A3L L;  1TWA A;  3GTK A;  4IP9 A;  4AR4 A;  5IP7 L;  3HOZ L;  5AI2 A;  4A3M L;  4JCW A;  3QWZ A;  1QYB A;  4C2M 1;  2N3E A;  3KYX A;  4RV0 A;  3ZG6 A;  2G6G A;  4AAY A;  1L8F A;  3H3V M;  3K35 A;  3TIW A;  4K9F A;  1QQT A;  1TWF L;  4AHC A;  4KB4 A;  2C6B A;  4CRY G;  4KDL A;  3NFP I;  3J7Y 1;  4A3J L;  3HAX C;  1CZ4 A;  1I3Q L;  5MGN A;  5JVH 1;  1TWC L;  1G8J A;  2A68 D;  2JIM A;  3SUL A;  4BBS L;  3M3G A;  4D3Z A;  2VUM L;  1H0H A;  4QIW A;  3LWO B;  3GTL L;  3K5L A;  2LCQ A;  2VK9 A;  4OYD B;  3PWF A;  1R9T L;  4FBS A;  3X2M A;  2O5J D;  2IV2 X;  3K58 A;  4KDI A;  2EZC A;  2LPI A;  2M4Y A;  1PPY A;  1VCX A;  1PFV A;  3X2J A;  4AVR A;  3K5N A;  2CKA A;  3PO3 L;  3IR7 A;  5C3E L;  1C09 A;  4A3B L;  3LPE B;  2AE0 X;  2H12 A;  4JS7 A;  3SUK A;  2Y0S P;  4C5S A;  4A3C L;  1RR8 C;  2MQA A;  4ZN1 B;  2X0Q A;  4A3F L;  1CR5 A;  1TWG A;  4XGH A;  3K5M A;  2MX9 A;  4AHY A;  1RYT A;  4E6Y A;  3H0G L;  4ME3 A;  2AQL A;  3S17 L;  2G5D A;  1OWB A;  3LWQ B;  2V0F A;  3JR7 A;  2JI2 A;  1BFY A;  3ML1 A;  1I50 A;  1NNQ A;  2F4Q A;  1WCM A;  3M4A A;  3IAY A;  1AW8 B;  2Y0N A;  4JAD A;  4JJO A;  5GAG c;  3LF9 A;  1VZI A;  4AR5 A;  2HWG A;  2YUJ A;  4BY1 L;  3KYL A;  1BQ8 A;  3HOU L;  4KO8 A;  2JA7 A;  5T5M D;  1H7V A;  5MFZ A;  3LNL A;  1QCV A;  3EZB A;  4KAW X;  3KYU A;  2RDV A;  3RZO L;  3GTP A;  3WWL A;  3S1R L;  1UHE A;  2A6H D;  1K83 A;  1LKM A;  4CEI A;  2YII A;  2E2J L;  1E60 A;  5EIO C;  1Y1V L;  4CRZ A;  5FTK A;  5JSN B; 
#chains in the Genus database with same CATH homology
 2K3Q A;  4XXB B;  3P8B A;  2A69 D;  3U4Q A;  1T9Q A;  2WB1 A;  1VC3 B;  5K2M E;  2JI3 A;  5GAH c;  1DMR A;  1S3S A;  4RXN A;  3A44 A;  1LKP A;  3MAQ A;  3DMR A;  2JIQ A;  3QC8 A;  1IRO A;  1DD5 A;  1YUZ A;  4YWL A;  2VL6 A;  5DYG A;  1TWF A;  1GE9 A;  1T9O A;  4EJ3 A;  1I3Q A;  2KI8 A;  1TWC A;  2FIO A;  4JAG A;  2YU9 A;  1OWC A;  1BE7 A;  8RXN A;  3GTL A;  4FYD A;  1RYQ A;  2K3N A;  2J9U B;  3K57 A;  6RXN A;  1Y5I A;  1E5V A;  5JSB B;  4JAE A;  1YUX A;  1R9T A;  3LRD A;  2GAE A;  1NXG A;  4H3T A;  2VPX A;  4KOD A;  2LKM B;  4O26 A;  4AHZ A;  4QCL A;  3SS2 A;  2A6E D;  3WWN B;  3MPS A;  1K4T A;  1R27 A;  1SMW A;  3TM7 B;  1TGO A;  1ZYR D;  2CW0 D;  1SC7 A;  2E7Z A;  1RDV A;  5JVG 1;  2LTH A;  3H0G A;  1T8I A;  4AHX A;  4AON B;  5T5I D;  4FXD A;  1R7R A;  4AN8 A;  7RXN A;  2KKD A;  5GLF A;  1PYQ A;  1YK5 A;  1EJ9 A;  1IU5 A;  2PIC A;  2CKC A;  3U44 A;  2FIP A;  1VZG A;  2LYI A;  2WAQ A;  3K5O A;  3B08 B;  1Q8I A;  3P9A A;  5MLC 3;  3VPB E;  1JYB A;  3HU1 A;  1B71 A;  2MX8 A;  1A35 A;  4KB2 A;  5EIN C;  1FDI A;  1LTL A;  5IZ2 A;  1T9P A;  1Y1V A;  5MF6 A;  3PIP 1;  1G8K A;  2R92 A;  2X0O A;  1RDG A;  4G6B A;  2PMZ A;  3PIO 1;  2XJP A;  1CAD A;  5RXN A;  3O5A A;  4CEH A;  1S2Z A;  1PT1 A;  3KYY A;  1LKO A;  5C1B A;  2M6O A;  5FTJ A;  3QVD A;  4GA5 A;  4U67 1;  1ZRP A;  1YNJ D;  1SEU A;  4LHL A;  5C18 A;  2LPJ A;  2VPW A;  5IY0 A;  1YK4 A;  1E18 A;  5DM6 1;  4L8I A;  3QQ7 A;  2JIR A;  4GS7 D;  1RWD A;  1B2O A;  5EPP A;  1NH3 A;  4AI1 A;  4JAF A;  1DVB A;  1IU6 A;  1Z92 B;  3LHP S;  3PKI A;  1A36 A;  2VPY A;  3OUG A;  2JI1 A;  1SIW A;  1DMS A;  2PVE A;  4POF A;  4CEJ A;  1Y1W A;  1R0H A;  1PYU B;  3GTG A;  2ZIX A;  4AHW A;  5AN9 H;  2M6P A;  2Y0S A;  4CS0 A;  1FDO A;  4F3E A;  5H1S c;  1PQE A;  2R7Z A;  1AA6 A;  2XJS A;  2V45 A;  4LHN A;  1PQH A;  4ZN3 B;  1Y4Z A;  4NOK A;  5AI3 A;  1R0G A;  1KQF A;  2NYA A;  1RRJ A;  4D3Y A;  3WVO A;  4TPU A;  1WLF A;  3KYV A;  3DU6 A;  4IP8 A;  2V3B B;  2NAP A;  3GTM A;  1SFO A;  2PSM C;  1PQF A;  3QQC E;  1FHH A;  4AI0 A;  2PVX A;  5MFP A;  2F5J A;  1EH1 A;  3GTJ A;  1EK8 A;  5FTN A;  2K2D A;  2B9S B;  3CQZ A;  2M4V A;  1S24 A;  1BRF A;  3FKI A;  2GMG A;  5FTM A;  4LMO A;  2X0P A;  1IRN A;  3CZB A;  1WQH A;  2ERJ A;  5GAE c;  4AOK B;  4KLN A;  1EU1 A;  4JLR C;  1WQG A;  2NVX A;  1WJV A;  4AZD A;  2XJT A;  2Z3Q B;  4UY8 1;  3CF2 A;  2XJR A;  3PZA A;  1K4S A;  1RB9 A;  1DX8 A;  3RZT A;  1R0F A;  3KYW A;  3MSU A;  5DYI A;  4AI2 A;  1SMU A;  4B8C D;  3QQ8 A;  2R4G A;  5GAD c;  2DMR A;  1E8J A;  5FTL A;  4Q5V A;  1MIU A;  2Z3R B;  4TVM A;  4NOH A;  2NVY A;  2JIP A;  3PLX B;  2XJU A;  2PJJ A;  1SMM A;  1TL8 A;  2E2I A;  1WQF A;  5MLC 9;  3SJR A;  1YNN D;  2HR5 A;  2PNW A;  2B63 A;  1CAA A;  1TMO A;  2CR8 A;  3HU2 A;  4FGU A;  1YLE A;  2N1D B;  4DMR A;  4NOL A;  4KC6 A;  2V3V A;  4Q5G A;  1IS1 A;  1HQM D;  2BE5 D;  3B0A B;  1VZH A;  2PJH B;  1FHM A;  3GTO A;  2PPT A;  1IW7 D;  1R0J A;  2NYD A;  1V9M A;  3RZ6 A;  1A31 A;  1CZ5 A;  4AYB A;  5DM7 1;  2JIO A;  3LR6 A;  2KN9 A;  1ISE A;  3IR5 A;  2MS3 A;  2R93 A;  3RYG A;  4GA6 A;  2EEO B;  1KQG A;  4NOM A;  4POG A;  4AI3 A;  1QCS A;  3IU3 I;  1BQ9 A;  2ERS A;  4C2M A;  1E61 A;  1PT0 A;  1B2J A;  1B13 A;  1R0I A;  3P2A A;  4AR6 A;  4KDD A;  2JA6 A;  1UHD A;  1E32 A;  1NXE A;  1TWH A;  2E2H A;  3HU3 A;  3IR6 A;  5B6C A;  3LR2 A;  1ODH A;  2DSX A;  2L0Z A;  4AR3 A;  4WFN 1;  1ZC1 A;  2B5I D;  3LR8 A;  2C6A A;  1I6V D;  3PKJ A;  2QL0 A;  1SMY D;  1R49 A;  3GTQ A;  5CQG A;  2JA5 A;  1LPQ A;  4V19 6;  2AYJ A;  2V0E A;  1R5Z A;  2C45 A;  1Y69 8;  2VPZ A;  2K3O A;  1Q16 A;  4YWM A;  2XJV A;  3K59 A;  2VUM A;  1S30 A;  3DU5 A;  3J7Z 1;  1YV1 A;  2PI8 A;  1H5N A;  1OGY A;  5C9H A;  4D7Z B;  2XJQ A;  4GFQ A;  2PYA A;  1QDN A;  3HKZ A;  1TWA A;  3GTK A;  4IP9 A;  4AR4 A;  5AI2 A;  3QWZ A;  1QYB A;  2N3E A;  3KYX A;  4RV0 A;  3ZG6 A;  2G6G A;  4AAY A;  3K35 A;  3TIW A;  4K9F A;  4AHC A;  4KB4 A;  2C6B A;  4CRY G;  4KDL A;  3NFP I;  3J7Y 1;  1CZ4 A;  5MGN A;  5JVH 1;  1G8J A;  2A68 D;  2JIM A;  4D3Z A;  1H0H A;  4QIW A;  3K5L A;  2LCQ A;  2VK9 A;  4OYD B;  3PWF A;  4FBS A;  2O5J D;  2IV2 X;  3K58 A;  4KDI A;  2LPI A;  2M4Y A;  1PPY A;  1VCX A;  3K5N A;  2CKA A;  3IR7 A;  1C09 A;  3LPE B;  2AE0 X;  2H12 A;  1RR8 C;  2MQA A;  4ZN1 B;  2X0Q A;  1CR5 A;  1TWG A;  4XGH A;  3K5M A;  2MX9 A;  4AHY A;  1RYT A;  4E6Y A;  4ME3 A;  2AQL A;  2G5D A;  1OWB A;  2V0F A;  2JI2 A;  1BFY A;  3ML1 A;  1I50 A;  1NNQ A;  2F4Q A;  1WCM A;  3M4A A;  3IAY A;  1AW8 B;  2Y0N A;  4JAD A;  5GAG c;  3LF9 A;  1VZI A;  4AR5 A;  2YUJ A;  3KYL A;  1BQ8 A;  4KO8 A;  5T5M D;  2JA7 A;  1H7V A;  5MFZ A;  3LNL A;  1QCV A;  4KAW X;  3KYU A;  2RDV A;  1UHE A;  3GTP A;  3WWL A;  2A6H D;  1K83 A;  1LKM A;  4CEI A;  1E60 A;  5EIO C;  4CRZ A;  5FTK A;  5JSN B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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