2O5JD

Crystal structure of the t. thermophilus rnap polymerase elongation complex with the ntp substrate analog
Total Genus 275
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
275
sequence length
1504
structure length
1264
Chain Sequence
KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGAADITQGLPRVIELFEARRPKAKAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEAVEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for substrate loading in bacterial RNA polymerase.
pubmed doi rcsb
molecule tags Transferase/dna-rna hybrid
molecule keywords 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP
total genus 275
structure length 1264
sequence length 1504
chains with identical sequence N
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2006-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00623 RNA_pol_Rpb1_2 RNA polymerase Rpb1, domain 2
D PF04983 RNA_pol_Rpb1_3 RNA polymerase Rpb1, domain 3
D PF04997 RNA_pol_Rpb1_1 RNA polymerase Rpb1, domain 1
D PF04998 RNA_pol_Rpb1_5 RNA polymerase Rpb1, domain 5
D PF05000 RNA_pol_Rpb1_4 RNA polymerase Rpb1, domain 4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.30 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 2o5jD05
1.10.274.100 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Enzyme I; Chain A, domain 2 2o5jD04
2.20.28.170 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2o5jD07
2.40.40.70 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2o5jD03
1SFOA 2R7ZA 2A69D 1TWGA 4C2MA 1I3QA 2O5JD 1SMYD 3H0GA 2A68D 2JA7A 2WAQA 1TWHA 3GTMA 1YNJD 2CW0D 2BE5D 1HQMD 3GTJA 3GTOA 2A6HD 2JA6A 3FKIA 1K83A 2VUMA 3GTLA 3GTQA 1YNND 2YU9A 3GTPA 1R9TA 2R93A 1IW7D 2E2HA 4QIWA 1TWFA 3GTGA 3HKZA 1Y1WA 3CQZA 1I6VD 1Y1VA 3GTKA 2R92A 2B63A 1ZYRD 2PMZA 4AYBA 1I50A 1TWCA 2Y0SA 2A6ED 2E2IA 1WCMA 2JA5A 2NVXA 1TWAA 2NVYA 2WB1A
chains in the Genus database with same CATH superfamily
2ENGA 2EEOB 3EZAA 4IP8A 1TWGL 3KYXA 3GTOA 5MGNA 4CRZA 1DVBA 4KLNA 1Y4ZA 5GAEc 2FIPA 4AZDA 3M4AA 1QYBA 1LTLA 1F4LA 1QCVA 1SEUA 3QWZA 1LKOA 4F3EA 3ML1A 1T9OA 1SMWA 1T9PA 1FHHA 3GTKL 4CEIA 1NH3A 1K4TA 3P2AA 4TPUA 2G5DA 1RYQA 3SS2A 3HAXC 4KDIA 3X2GA 1NXEA 4XXBB 2XJPA 1FDOA 1SMUA 3KYYA 1QQTA 2A68D 2FIOA 1B13A 4A3ML 3K5LA 2PYAA 1WLFA 2VPWA 1PFWA 1HD5A 1S3SA 3TIWA 1K83L 2VUML 3MQKB 2WAQP 5M3FL 4JJOA 1R0IA 2B63A 1ZYRD 1YUXA 1B71A 3X2JA 4AHCA 1OGYA 1CADA 2QL0A 5DM71 2A6ED 3M3GA 2JA5A 3SUKA 4YWLA 1SMMA 4D3ZA 3ENGA 3P9AA 2MQAA 4GFQA 5IP7L 1EK8A 2N3EA 3LR6A 3FDJA 4C6GA 2PJJA 3GTLL 2PVEA 2E2HL 3K35A 4JADA 5M5XL 5AN9H 4A3LL 2R4GA 4KB2A 2R92A 2MX9A 4KODA 4AHYA 2PI8A 5DYGA 1YLEA 1R5ZA 4LHLA 5GLFA 3S17L 2LPJA 4AVRA 3HU1A 4E6YA 1TWCL 5T5MD 1BE7A 3HKZP 3JR7A 3X2OA 2A69D 1ODHA 2C6AA 1UHDA 2Y0SP 5IYDL 5IYBL 4FGUA 1Z92B 2C6BA 4QCLA 4AOKB 3GTQA 4CEJA 4AR5A 1E8JA 3M4OL 1TL8A 2AQLA 3X2IA 2AYJA 1NXGA 4OYDB 3K5MA 5GAGc 3DMRA 4FBSA 4CQ5A 1RDGA 4A93L 2DMRA 1Y2MA 1EJ9A 2KI8A 3K59A 2WB1A 2VL6A 2VPXA 1WCML 5IZ2A 2XJVA 4V2RA 5EINC 3X2LA 3CZBA 1TWGA 1H7VA 3LNLA 4XGHA 3S1ML 3PZAA 1I3QL 2JA7L 1BRFA 3H3VM 4Q5VA 5GM9A 3MPSA 3TM7B 3GTJL 4GA5A 4AONB 1LKMA 4QIWA 3LR8A 1N10A 2PPTA 5FTJA 3GTKA 3J7Y1 1PFVA 1Q16A 1PQFA 3HOXL 1BW4A 1I50L 1SIWA 1BQ9A 4V2QA 1YUZA 1EH1A 3P8BA 4GA6A 1LKPA 1TWAL 3SUMA 1YK4A 5C18A 4WFN1 2EZCA 3NZ4A 5H1Sc 3RZDL 2JIMA 3KYWA 5C3EL 1G8KA 2X0QA 4JS7A 4JAFA 3PKJA 5M5WL 5B6CA 1K83A 2VUMA 2JA6L 4FG2A 2KN9A 3K57A 2XJTA 4C3JL 1KQGA 4X6AL 3PO3L 2LCQA 1ZRPA 3PIP1 5JSBB 1ISEA 1CAAA 2K3NA 4BABA 1YK5A 1WC2A 2EY4E 5DM61 4U671 5FTMA 5FTLA 1JYBA 2HWGA 1FDIA 3SJRA 5T5ID 3S14L 1DX8A 1PFUA 1PT1A 1SFOL 3A44A 1SMYD 2K2DA 2WAQA 3KYUA 3X2HA 2JIQA 4JAGA 3HU3A 1HQMD 3QVDA 2A6HD 1QDNA 2GAEA 3PLXB 4CEHA 1E60A 3GTLA 3RZ6A 1Y5IA 2E2HA 3X2PA 4FXDA 3FKIL 1R0HA 1RWDA 4A3BL 1MIUA 2XJRA 3CF2A 2LKMB 2X0PA 4AI0A 1R49A 4C5RA 5MF6A 1EZBA 1TWCA 4AHXA 5C4XL 4AI3A 2CKCA 4NOLA 1L8FA 2Z3QB 2M4YA 1R27A 4CRYG 2YUJA 4LHNA 1VZGA 2LYIA 3KYVA 1V9MA 3MSUA 3RYGA 3IR7A 2JIOA 4C2MA 4KO8A 3HOUL 3HJWB 5FTNA 4B8CD 4Q5GA 4RV0A 4YWMA 4V196 2RFKB 2M6OA 1E5VA 4JAEA 4ZM7A 4AN8A 4BAAA 2V0EA 4TVMA 4EJ3A 1TWFA 2Y0NA 3GTPL 1AW8B 3HKZA 3IAYA 2K3QA 1RB9A 2V0FA 4AR3A 1PQEA 1LPQA 2APOB 4ME3A 4L48A 2PVXA 3CQZL 4AHWA 1Y1VL 2AQCA 1VZIA 3K5OA 4KB4A 1K4SA 1A35A 1WCMA 1P7PA 3H97A 2LPIA 4KAWX 3H9BA 2E2IL 1IROA 4POGA 3H9CA 2G6GA 4A3KL 1I3QA 3LRDA 2PMZP 3X2KA 4C2M1 5IYCL 2JA7A 1R7RA 1T6JA 4AI2A 3GTJA 3QQCE 5MLC3 5FLML 3MAQA 1PZXA 3LWVB 4D7ZB 1YNND 1BFYA 3PIO1 4JCWA 1R9TL 3HOZL 1TWFL 3IR6A 1Y1WL 2MS3A 2HCZX 1I50A 4FFTA 1Y698 2NVQL 1PPYA 4KDLA 4A3FL 3I4ML 4BBRL 1TWAA 2EZBA 2CR8A 4A3CL 2GMGA 3LF9A 2R7ZA 1Q8IA 1IRNA 1NNQA 4NOHA 2E7ZA 4AYBP 1IU6A 1E61A 4NOKA 3LPEB 2AE0X 3H0GL 1R0GA 2BE5D 2JA6A 4BXXL 2ERSA 5CQGA 4AAYA 1A36A 2F4QA 1EZAA 1UHEA 5GADc 4BY7L 1B2OA 1DD5A 2CKAA 3QQ8A 3GTGL 3PKIA 4K9FA 3DU6A 1RRJA 2MP0A 4H3TA 1T6PA 1CR5A 1RR8C 5H4UA 4ZN1B 1SFOA 4C5UA 2NVYL 3OUGA 3LWQB 1R0FA 2R7ZL 1VC3B 3VPBE 1PFYA 5MLC9 1TWHL 2VK9A 2JIRA 1VCXA 3FKIA 3RZTA 5K2ME 4POFA 3EZBA 3LWPB 3S2DL 4L8IA 3I4NL 4ZN3B 1WQGA 3K5NA 2YU9L 2R93L 3PWFA 1OWBA 2V3VA 2NVTL 4NOMA 2DSXA 4C3IL 1A31A 4BY1L 2HR5A 2NYAA 6RXNA 1QCSA 3S16L 5C44L 5FJ8L 2EZAA 3PL5A 3QQ7A 1CZ4A 3B08B 5IP9L 3M3YL 1YNJD 2YIIA 2KQAA 3HOWL 2RDVA 3GTML 2L0ZA 1T8IA 5IY0A 5MFZA 5RXNA 4A3DL 1I6HL 3D30A 4LMOA 3GTPA 2E2JL 2V45A 1IW7D 2PSMC 3O5AA 3CQZA 1BQ8A 1Y1VA 3J7Z1 1B2JA 1PYQA 1S2ZA 3K7AL 3ZG6A 3HOYL 2JI1A 1DMRA 2E2IA 2JI2A 3S1QL 2NVXA 5GLXA 4KC6A 3HJYB 5JSNB 3U4QA 3WWNB 3S1RL 3X2MA 5MFPA 4CS0A 2ZIXA 1W27A 4UY81 4C3HL 2H12A 3GTOL 4FYDA 1YV1A 4RXNA 2Z3RB 1R9TA 4AI1A 1DMSA 3S2HL 1Y1WA 2B5ID 1I6VD 3X2NA 3B0AB 1E18A 2AUSB 4FERA 2PMZA 5GAHc 1PYUB 5GLYA 2Y0SA 3K58A 5C9HA 1OA7A 1TGOA 2M4VA 2ERJA 1IS1A 4C5SA 5M3ML 3SUJA 5C1BA 2XJQA 3DU5A 1EU1A 4DMRA 3KYLA 2KKDA 5AI3A 8RXNA 2NVXL 2V3BB 3U44A 3H0GA 2JA8L 4FG4A 4JP6A 1RDVA 4ENGA 4A3GL 1BW3A 1WJVA 1KQFA 4JLRC 5C4JL 2B9SB 4G6BA 2N1DB 1GE9A 1R0JA 1WQHA 2K3OA 3GTGA 2LTHA 4IP9A 2IV2X 4A3EL 1RYTA 1ZC1A 4AYBA 1WQFA 2B63L 2XJUA 1E32A 1TMOA 2NVYA 2JA5L 2PNWA 5EPPA 2HROA 3IU3I 2HVYC 3LWRB 7RXNA 1S24A 1TWHA 1T9QA 3IR5A 1AA6A 1ZYMA 1C09A 3S1NL 2M6PA 1IU5A 3S15L 2VPZA 1SC7A 2YU9A 2R93A 2JI3A 5FTKA 5DYIA 1S30A 3QC8A 2X0OA 4Y52L 3HOVL 5AI2A 2XJSA 3RZOL 1VZHA 1OA9A 3H99A 3PO2L 2R92L 2MX8A 4GS7D 1H5NA 5M5YL 2JIPA 3HU2A 4JP7A 2PJHB 3WVOA 3LWOB 4A3IL 2O5JD 1OWCA 2NYDA 3GTMA 4AHZA 2NAPA 2CW0D 1PT0A 4KDDA 3WWLA 2WB1P 4A3JL 5JVH1 3NFPI 1FHMA 3GTQL 2BH0A 3LHPS 4BBSL 1PQHA 2PICA 3EZEA 4AR6A 1G8JA 2J9UB 2C45A 4AR4A 1CZ5A 3SULA 4QIWP 4Y7NL 5EIOC 2VPYA 5JVG1 3LR2A 1H0HA 4D3YA 2F5JA 4O26A
chains in the Genus database with same CATH topology
2EEOB 4IP8A 3KYXA 3GTOA 5MGNA 4CRZA 1DVBA 4KLNA 1Y4ZA 5GAEc 2FIPA 4AZDA 3M4AA 1QYBA 1LTLA 1QCVA 1SEUA 3QWZA 1LKOA 4F3EA 3ML1A 1T9OA 1SMWA 1T9PA 1FHHA 4CEIA 1NH3A 1K4TA 3P2AA 4TPUA 2G5DA 1RYQA 3SS2A 4KDIA 1NXEA 4XXBB 2XJPA 1FDOA 1SMUA 3KYYA 2A68D 2FIOA 1B13A 3K5LA 2PYAA 1WLFA 2VPWA 1S3SA 3TIWA 1R0IA 2B63A 1ZYRD 1YUXA 1B71A 4AHCA 1OGYA 1CADA 2QL0A 5DM71 2A6ED 2JA5A 4YWLA 1SMMA 4D3ZA 3P9AA 2MQAA 4GFQA 1EK8A 2N3EA 3LR6A 2PJJA 2PVEA 3K35A 4JADA 5AN9H 2R4GA 4KB2A 2R92A 2MX9A 4KODA 4AHYA 2PI8A 5DYGA 1YLEA 1R5ZA 4LHLA 5GLFA 2LPJA 3HU1A 4E6YA 5T5MD 1BE7A 2A69D 1ODHA 2C6AA 1UHDA 4FGUA 1Z92B 2C6BA 4QCLA 4AOKB 3GTQA 4CEJA 4AR5A 1E8JA 1TL8A 2AQLA 2AYJA 1NXGA 4OYDB 3K5MA 5GAGc 3DMRA 4FBSA 1RDGA 2DMRA 1EJ9A 2KI8A 3K59A 2WB1A 2VL6A 2VPXA 5EINC 2XJVA 5IZ2A 3CZBA 1TWGA 1H7VA 3LNLA 4XGHA 3PZAA 1BRFA 4Q5VA 3MPSA 3TM7B 4GA5A 4AONB 1LKMA 4QIWA 3LR8A 2PPTA 5FTJA 3GTKA 3J7Y1 1Q16A 1PQFA 1SIWA 1BQ9A 1YUZA 1EH1A 3P8BA 4GA6A 1LKPA 1YK4A 5C18A 4WFN1 5H1Sc 2JIMA 3KYWA 1G8KA 2X0QA 4JAFA 3PKJA 5B6CA 1K83A 2VUMA 2KN9A 3K57A 2XJTA 1KQGA 2LCQA 1ZRPA 3PIP1 5JSBB 1ISEA 1CAAA 2K3NA 1YK5A 4U671 5DM61 5FTMA 5FTLA 1JYBA 1FDIA 3SJRA 5T5ID 1DX8A 1PT1A 3A44A 1SMYD 2K2DA 2WAQA 3KYUA 2JIQA 4JAGA 3HU3A 1HQMD 3QVDA 2A6HD 1QDNA 2GAEA 3PLXB 4CEHA 1E60A 3GTLA 3RZ6A 1Y5IA 2E2HA 4FXDA 1R0HA 1RWDA 1MIUA 2XJRA 3CF2A 2LKMB 2X0PA 4AI0A 1R49A 5MF6A 1TWCA 4AHXA 4AI3A 2CKCA 4NOLA 2Z3QB 2M4YA 1R27A 4CRYG 2YUJA 4LHNA 1VZGA 2LYIA 3KYVA 1V9MA 3MSUA 3RYGA 3IR7A 2JIOA 4C2MA 4KO8A 5FTNA 4B8CD 4Q5GA 4RV0A 4YWMA 4V196 2M6OA 1E5VA 4JAEA 4AN8A 2V0EA 4TVMA 4EJ3A 1TWFA 2Y0NA 1AW8B 3HKZA 3IAYA 2K3QA 2V0FA 1RB9A 4AR3A 1PQEA 1LPQA 4ME3A 2PVXA 4AHWA 1VZIA 3K5OA 4KB4A 1K4SA 1A35A 1WCMA 2LPIA 4KAWX 1IROA 4POGA 2G6GA 1I3QA 3LRDA 2JA7A 1R7RA 4AI2A 3GTJA 3QQCE 5MLC3 3MAQA 4D7ZB 1YNND 1BFYA 3PIO1 3IR6A 2MS3A 1I50A 1Y698 1PPYA 4KDLA 1TWAA 2CR8A 2GMGA 3LF9A 2R7ZA 1Q8IA 1IRNA 1NNQA 4NOHA 2E7ZA 1IU6A 1E61A 4NOKA 3LPEB 2AE0X 1R0GA 2BE5D 2JA6A 2ERSA 5CQGA 4AAYA 1A36A 2F4QA 1UHEA 5GADc 1B2OA 1DD5A 2CKAA 3QQ8A 3PKIA 4K9FA 3DU6A 1RRJA 4H3TA 1CR5A 1RR8C 4ZN1B 1SFOA 3OUGA 1R0FA 1VC3B 3VPBE 5MLC9 2VK9A 2JIRA 1VCXA 3FKIA 3RZTA 5K2ME 4POFA 4L8IA 4ZN3B 1WQGA 3K5NA 3PWFA 1OWBA 2V3VA 4NOMA 2DSXA 1A31A 2HR5A 2NYAA 6RXNA 1QCSA 3QQ7A 1CZ4A 3B08B 1YNJD 2RDVA 2L0ZA 1T8IA 5IY0A 5MFZA 5RXNA 4LMOA 3GTPA 2V45A 1IW7D 2PSMC 3O5AA 3CQZA 1BQ8A 1Y1VA 3J7Z1 1B2JA 1PYQA 1S2ZA 3ZG6A 1DMRA 2JI1A 2E2IA 2JI2A 2NVXA 4KC6A 5JSNB 3U4QA 3WWNB 5MFPA 4CS0A 2ZIXA 4UY81 2H12A 4FYDA 1YV1A 4RXNA 2Z3RB 1R9TA 4AI1A 1DMSA 1Y1WA 2B5ID 1I6VD 3B0AB 1E18A 2PMZA 5GAHc 1PYUB 2Y0SA 3K58A 5C9HA 1TGOA 2M4VA 2ERJA 1IS1A 5C1BA 2XJQA 3DU5A 1EU1A 4DMRA 3KYLA 2KKDA 5AI3A 8RXNA 2V3BB 3U44A 3H0GA 1RDVA 1WJVA 1KQFA 4JLRC 2B9SB 4G6BA 2N1DB 1GE9A 1R0JA 1WQHA 2K3OA 3GTGA 2LTHA 4IP9A 2IV2X 1RYTA 1ZC1A 4AYBA 1WQFA 2XJUA 1E32A 1TMOA 2NVYA 2PNWA 5EPPA 3IU3I 7RXNA 1S24A 1TWHA 1T9QA 3IR5A 1AA6A 1C09A 2M6PA 1IU5A 2VPZA 1SC7A 2YU9A 2R93A 2JI3A 5FTKA 5DYIA 1S30A 3QC8A 2X0OA 5AI2A 2XJSA 1VZHA 2MX8A 4GS7D 1H5NA 2JIPA 3HU2A 2PJHB 3WVOA 2O5JD 1OWCA 2NYDA 3GTMA 4AHZA 2NAPA 2CW0D 1PT0A 4KDDA 3WWLA 5JVH1 3NFPI 1FHMA 3LHPS 1PQHA 2PICA 4AR6A 1G8JA 2J9UB 2C45A 4AR4A 1CZ5A 5EIOC 2VPYA 5JVG1 3LR2A 1H0HA 4D3YA 2F5JA 4O26A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SFO A;  2R7Z A;  2A69 D;  1TWG A;  4C2M A;  1I3Q A;  2O5J D;  1SMY D;  3H0G A;  2A68 D;  2JA7 A;  2WAQ A;  1TWH A;  3GTM A;  1YNJ D;  2CW0 D;  2BE5 D;  1HQM D;  3GTJ A;  3GTO A;  2A6H D;  2JA6 A;  3FKI A;  1K83 A;  2VUM A;  3GTL A;  3GTQ A;  1YNN D;  2YU9 A;  3GTP A;  1R9T A;  2R93 A;  1IW7 D;  2E2H A;  4QIW A;  1TWF A;  3GTG A;  3HKZ A;  1Y1W A;  3CQZ A;  1I6V D;  1Y1V A;  3GTK A;  2R92 A;  2B63 A;  1ZYR D;  2PMZ A;  4AYB A;  1I50 A;  1TWC A;  2Y0S A;  2A6E D;  2E2I A;  1WCM A;  2JA5 A;  2NVX A;  1TWA A;  2NVY A;  2WB1 A; 
#chains in the Genus database with same CATH topology
 2ENG A;  2EEO B;  3EZA A;  4IP8 A;  1TWG L;  3KYX A;  3GTO A;  5MGN A;  4CRZ A;  1DVB A;  4KLN A;  1Y4Z A;  5GAE c;  2FIP A;  4AZD A;  3M4A A;  1QYB A;  1LTL A;  1F4L A;  1QCV A;  1SEU A;  3QWZ A;  1LKO A;  4F3E A;  3ML1 A;  1T9O A;  1SMW A;  1T9P A;  1FHH A;  3GTK L;  4CEI A;  1NH3 A;  1K4T A;  3P2A A;  4TPU A;  2G5D A;  1RYQ A;  3SS2 A;  3HAX C;  4KDI A;  3X2G A;  1NXE A;  4XXB B;  2XJP A;  1FDO A;  1SMU A;  3KYY A;  1QQT A;  2A68 D;  2FIO A;  1B13 A;  4A3M L;  3K5L A;  2PYA A;  1WLF A;  2VPW A;  1PFW A;  1HD5 A;  1S3S A;  3TIW A;  1K83 L;  2VUM L;  3MQK B;  2WAQ P;  5M3F L;  4JJO A;  1R0I A;  2B63 A;  1ZYR D;  1YUX A;  1B71 A;  3X2J A;  4AHC A;  1OGY A;  1CAD A;  2QL0 A;  5DM7 1;  2A6E D;  3M3G A;  2JA5 A;  3SUK A;  4YWL A;  1SMM A;  4D3Z A;  3ENG A;  3P9A A;  2MQA A;  4GFQ A;  5IP7 L;  1EK8 A;  2N3E A;  3LR6 A;  3FDJ A;  4C6G A;  2PJJ A;  3GTL L;  2PVE A;  2E2H L;  3K35 A;  4JAD A;  5M5X L;  5AN9 H;  4A3L L;  2R4G A;  4KB2 A;  2R92 A;  2MX9 A;  4KOD A;  4AHY A;  2PI8 A;  5DYG A;  1YLE A;  1R5Z A;  4LHL A;  5GLF A;  3S17 L;  2LPJ A;  4AVR A;  3HU1 A;  4E6Y A;  1TWC L;  5T5M D;  1BE7 A;  3HKZ P;  3JR7 A;  3X2O A;  2A69 D;  1ODH A;  2C6A A;  1UHD A;  2Y0S P;  5IYD L;  5IYB L;  4FGU A;  1Z92 B;  2C6B A;  4QCL A;  4AOK B;  3GTQ A;  4CEJ A;  4AR5 A;  1E8J A;  3M4O L;  1TL8 A;  2AQL A;  3X2I A;  2AYJ A;  1NXG A;  4OYD B;  3K5M A;  5GAG c;  3DMR A;  4FBS A;  4CQ5 A;  1RDG A;  4A93 L;  2DMR A;  1Y2M A;  1EJ9 A;  2KI8 A;  3K59 A;  2WB1 A;  2VL6 A;  2VPX A;  1WCM L;  5IZ2 A;  2XJV A;  4V2R A;  5EIN C;  3X2L A;  3CZB A;  1TWG A;  1H7V A;  3LNL A;  4XGH A;  3S1M L;  3PZA A;  1I3Q L;  2JA7 L;  1BRF A;  3H3V M;  4Q5V A;  5GM9 A;  3MPS A;  3TM7 B;  3GTJ L;  4GA5 A;  4AON B;  1LKM A;  4QIW A;  3LR8 A;  1N10 A;  2PPT A;  5FTJ A;  3GTK A;  3J7Y 1;  1PFV A;  1Q16 A;  1PQF A;  3HOX L;  1BW4 A;  1I50 L;  1SIW A;  1BQ9 A;  4V2Q A;  1YUZ A;  1EH1 A;  3P8B A;  4GA6 A;  1LKP A;  1TWA L;  3SUM A;  1YK4 A;  5C18 A;  4WFN 1;  2EZC A;  3NZ4 A;  5H1S c;  3RZD L;  2JIM A;  3KYW A;  5C3E L;  1G8K A;  2X0Q A;  4JS7 A;  4JAF A;  3PKJ A;  5M5W L;  5B6C A;  1K83 A;  2VUM A;  2JA6 L;  4FG2 A;  2KN9 A;  3K57 A;  2XJT A;  4C3J L;  1KQG A;  4X6A L;  3PO3 L;  2LCQ A;  1ZRP A;  3PIP 1;  5JSB B;  1ISE A;  1CAA A;  2K3N A;  4BAB A;  1YK5 A;  1WC2 A;  2EY4 E;  5DM6 1;  4U67 1;  5FTM A;  5FTL A;  1JYB A;  2HWG A;  1FDI A;  3SJR A;  5T5I D;  3S14 L;  1DX8 A;  1PFU A;  1PT1 A;  1SFO L;  3A44 A;  1SMY D;  2K2D A;  2WAQ A;  3KYU A;  3X2H A;  2JIQ A;  4JAG A;  3HU3 A;  1HQM D;  3QVD A;  2A6H D;  1QDN A;  2GAE A;  3PLX B;  4CEH A;  1E60 A;  3GTL A;  3RZ6 A;  1Y5I A;  2E2H A;  3X2P A;  4FXD A;  3FKI L;  1R0H A;  1RWD A;  4A3B L;  1MIU A;  2XJR A;  3CF2 A;  2LKM B;  2X0P A;  4AI0 A;  1R49 A;  4C5R A;  5MF6 A;  1EZB A;  1TWC A;  4AHX A;  5C4X L;  4AI3 A;  2CKC A;  4NOL A;  1L8F A;  2Z3Q B;  2M4Y A;  1R27 A;  4CRY G;  2YUJ A;  4LHN A;  1VZG A;  2LYI A;  3KYV A;  1V9M A;  3MSU A;  3RYG A;  3IR7 A;  2JIO A;  4C2M A;  4KO8 A;  3HOU L;  3HJW B;  5FTN A;  4B8C D;  4Q5G A;  4RV0 A;  4YWM A;  4V19 6;  2RFK B;  2M6O A;  1E5V A;  4JAE A;  4ZM7 A;  4AN8 A;  4BAA A;  2V0E A;  4TVM A;  4EJ3 A;  1TWF A;  2Y0N A;  3GTP L;  1AW8 B;  3HKZ A;  3IAY A;  2K3Q A;  1RB9 A;  2V0F A;  4AR3 A;  1PQE A;  1LPQ A;  2APO B;  4ME3 A;  4L48 A;  2PVX A;  3CQZ L;  4AHW A;  1Y1V L;  2AQC A;  1VZI A;  3K5O A;  4KB4 A;  1K4S A;  1A35 A;  1WCM A;  1P7P A;  3H97 A;  2LPI A;  4KAW X;  3H9B A;  2E2I L;  1IRO A;  4POG A;  3H9C A;  2G6G A;  4A3K L;  1I3Q A;  3LRD A;  2PMZ P;  3X2K A;  4C2M 1;  5IYC L;  2JA7 A;  1R7R A;  1T6J A;  4AI2 A;  3GTJ A;  3QQC E;  5MLC 3;  5FLM L;  3MAQ A;  1PZX A;  3LWV B;  4D7Z B;  1YNN D;  1BFY A;  3PIO 1;  4JCW A;  1R9T L;  3HOZ L;  1TWF L;  3IR6 A;  1Y1W L;  2MS3 A;  2HCZ X;  1I50 A;  4FFT A;  1Y69 8;  2NVQ L;  1PPY A;  4KDL A;  4A3F L;  3I4M L;  4BBR L;  1TWA A;  2EZB A;  2CR8 A;  4A3C L;  2GMG A;  3LF9 A;  2R7Z A;  1Q8I A;  1IRN A;  1NNQ A;  4NOH A;  2E7Z A;  4AYB P;  1IU6 A;  1E61 A;  4NOK A;  3LPE B;  2AE0 X;  3H0G L;  1R0G A;  2BE5 D;  2JA6 A;  4BXX L;  2ERS A;  5CQG A;  4AAY A;  1A36 A;  2F4Q A;  1EZA A;  1UHE A;  5GAD c;  4BY7 L;  1B2O A;  1DD5 A;  2CKA A;  3QQ8 A;  3GTG L;  3PKI A;  4K9F A;  3DU6 A;  1RRJ A;  2MP0 A;  4H3T A;  1T6P A;  1CR5 A;  1RR8 C;  5H4U A;  4ZN1 B;  1SFO A;  4C5U A;  2NVY L;  3OUG A;  3LWQ B;  1R0F A;  2R7Z L;  1VC3 B;  3VPB E;  1PFY A;  5MLC 9;  1TWH L;  2VK9 A;  2JIR A;  1VCX A;  3FKI A;  3RZT A;  5K2M E;  4POF A;  3EZB A;  3LWP B;  3S2D L;  4L8I A;  3I4N L;  4ZN3 B;  1WQG A;  3K5N A;  2YU9 L;  2R93 L;  3PWF A;  1OWB A;  2V3V A;  2NVT L;  4NOM A;  2DSX A;  4C3I L;  1A31 A;  4BY1 L;  2HR5 A;  2NYA A;  6RXN A;  1QCS A;  3S16 L;  5C44 L;  5FJ8 L;  2EZA A;  3PL5 A;  3QQ7 A;  1CZ4 A;  3B08 B;  5IP9 L;  3M3Y L;  1YNJ D;  2YII A;  2KQA A;  3HOW L;  2RDV A;  3GTM L;  2L0Z A;  1T8I A;  5IY0 A;  5MFZ A;  5RXN A;  4A3D L;  1I6H L;  3D30 A;  4LMO A;  3GTP A;  2E2J L;  2V45 A;  1IW7 D;  2PSM C;  3O5A A;  3CQZ A;  1BQ8 A;  1Y1V A;  3J7Z 1;  1B2J A;  1PYQ A;  1S2Z A;  3K7A L;  3ZG6 A;  3HOY L;  2JI1 A;  1DMR A;  2E2I A;  2JI2 A;  3S1Q L;  2NVX A;  5GLX A;  4KC6 A;  3HJY B;  5JSN B;  3U4Q A;  3WWN B;  3S1R L;  3X2M A;  5MFP A;  4CS0 A;  2ZIX A;  1W27 A;  4UY8 1;  4C3H L;  2H12 A;  3GTO L;  4FYD A;  1YV1 A;  4RXN A;  2Z3R B;  1R9T A;  4AI1 A;  1DMS A;  3S2H L;  1Y1W A;  2B5I D;  1I6V D;  3X2N A;  3B0A B;  1E18 A;  2AUS B;  4FER A;  2PMZ A;  5GAH c;  1PYU B;  5GLY A;  2Y0S A;  3K58 A;  5C9H A;  1OA7 A;  1TGO A;  2M4V A;  2ERJ A;  1IS1 A;  4C5S A;  5M3M L;  3SUJ A;  5C1B A;  2XJQ A;  3DU5 A;  1EU1 A;  4DMR A;  3KYL A;  2KKD A;  5AI3 A;  8RXN A;  2NVX L;  2V3B B;  3U44 A;  3H0G A;  2JA8 L;  4FG4 A;  4JP6 A;  1RDV A;  4ENG A;  4A3G L;  1BW3 A;  1WJV A;  1KQF A;  4JLR C;  5C4J L;  2B9S B;  4G6B A;  2N1D B;  1GE9 A;  1R0J A;  1WQH A;  2K3O A;  3GTG A;  2LTH A;  4IP9 A;  2IV2 X;  4A3E L;  1RYT A;  1ZC1 A;  4AYB A;  1WQF A;  2B63 L;  2XJU A;  1E32 A;  1TMO A;  2NVY A;  2JA5 L;  2PNW A;  5EPP A;  2HRO A;  3IU3 I;  2HVY C;  3LWR B;  7RXN A;  1S24 A;  1TWH A;  1T9Q A;  3IR5 A;  1AA6 A;  1ZYM A;  1C09 A;  3S1N L;  2M6P A;  1IU5 A;  3S15 L;  2VPZ A;  1SC7 A;  2YU9 A;  2R93 A;  2JI3 A;  5FTK A;  5DYI A;  1S30 A;  3QC8 A;  2X0O A;  4Y52 L;  3HOV L;  5AI2 A;  2XJS A;  3RZO L;  1VZH A;  1OA9 A;  3H99 A;  3PO2 L;  2R92 L;  2MX8 A;  4GS7 D;  1H5N A;  5M5Y L;  2JIP A;  3HU2 A;  4JP7 A;  2PJH B;  3WVO A;  3LWO B;  4A3I L;  2O5J D;  1OWC A;  2NYD A;  3GTM A;  4AHZ A;  2NAP A;  2CW0 D;  1PT0 A;  4KDD A;  3WWL A;  2WB1 P;  4A3J L;  5JVH 1;  3NFP I;  1FHM A;  3GTQ L;  2BH0 A;  3LHP S;  4BBS L;  1PQH A;  2PIC A;  3EZE A;  4AR6 A;  1G8J A;  2J9U B;  2C45 A;  4AR4 A;  1CZ5 A;  3SUL A;  4QIW P;  4Y7N L;  5EIO C;  2VPY A;  5JVG 1;  3LR2 A;  1H0H A;  4D3Y A;  2F5J A;  4O26 A; 
#chains in the Genus database with same CATH homology
 2EEO B;  4IP8 A;  3KYX A;  3GTO A;  5MGN A;  4CRZ A;  1DVB A;  4KLN A;  1Y4Z A;  5GAE c;  2FIP A;  4AZD A;  3M4A A;  1QYB A;  1LTL A;  1QCV A;  1SEU A;  3QWZ A;  1LKO A;  4F3E A;  3ML1 A;  1T9O A;  1SMW A;  1T9P A;  1FHH A;  4CEI A;  1NH3 A;  1K4T A;  3P2A A;  4TPU A;  2G5D A;  1RYQ A;  3SS2 A;  4KDI A;  1NXE A;  4XXB B;  2XJP A;  1FDO A;  1SMU A;  3KYY A;  2A68 D;  2FIO A;  1B13 A;  3K5L A;  2PYA A;  1WLF A;  2VPW A;  1S3S A;  3TIW A;  1R0I A;  2B63 A;  1ZYR D;  1YUX A;  1B71 A;  4AHC A;  1OGY A;  1CAD A;  2QL0 A;  5DM7 1;  2A6E D;  2JA5 A;  4YWL A;  1SMM A;  4D3Z A;  3P9A A;  2MQA A;  4GFQ A;  1EK8 A;  2N3E A;  3LR6 A;  2PJJ A;  2PVE A;  3K35 A;  4JAD A;  5AN9 H;  2R4G A;  4KB2 A;  2R92 A;  2MX9 A;  4KOD A;  4AHY A;  2PI8 A;  5DYG A;  1YLE A;  1R5Z A;  4LHL A;  5GLF A;  2LPJ A;  3HU1 A;  4E6Y A;  5T5M D;  1BE7 A;  2A69 D;  1ODH A;  2C6A A;  1UHD A;  4FGU A;  1Z92 B;  2C6B A;  4QCL A;  4AOK B;  3GTQ A;  4CEJ A;  4AR5 A;  1E8J A;  1TL8 A;  2AQL A;  2AYJ A;  1NXG A;  4OYD B;  3K5M A;  5GAG c;  3DMR A;  4FBS A;  1RDG A;  2DMR A;  1EJ9 A;  2KI8 A;  3K59 A;  2WB1 A;  2VL6 A;  2VPX A;  5EIN C;  2XJV A;  5IZ2 A;  3CZB A;  1TWG A;  1H7V A;  3LNL A;  4XGH A;  3PZA A;  1BRF A;  4Q5V A;  3MPS A;  3TM7 B;  4GA5 A;  4AON B;  1LKM A;  4QIW A;  3LR8 A;  2PPT A;  5FTJ A;  3GTK A;  3J7Y 1;  1Q16 A;  1PQF A;  1SIW A;  1BQ9 A;  1YUZ A;  1EH1 A;  3P8B A;  4GA6 A;  1LKP A;  1YK4 A;  5C18 A;  4WFN 1;  5H1S c;  2JIM A;  3KYW A;  1G8K A;  2X0Q A;  4JAF A;  3PKJ A;  5B6C A;  1K83 A;  2VUM A;  2KN9 A;  3K57 A;  2XJT A;  1KQG A;  2LCQ A;  1ZRP A;  3PIP 1;  5JSB B;  1ISE A;  1CAA A;  2K3N A;  1YK5 A;  4U67 1;  5DM6 1;  5FTM A;  5FTL A;  1JYB A;  1FDI A;  3SJR A;  5T5I D;  1DX8 A;  1PT1 A;  3A44 A;  1SMY D;  2K2D A;  2WAQ A;  3KYU A;  2JIQ A;  4JAG A;  3HU3 A;  1HQM D;  3QVD A;  2A6H D;  1QDN A;  2GAE A;  3PLX B;  4CEH A;  1E60 A;  3GTL A;  3RZ6 A;  1Y5I A;  2E2H A;  4FXD A;  1R0H A;  1RWD A;  1MIU A;  2XJR A;  3CF2 A;  2LKM B;  2X0P A;  4AI0 A;  1R49 A;  5MF6 A;  1TWC A;  4AHX A;  4AI3 A;  2CKC A;  4NOL A;  2Z3Q B;  2M4Y A;  1R27 A;  4CRY G;  2YUJ A;  4LHN A;  1VZG A;  2LYI A;  3KYV A;  1V9M A;  3MSU A;  3RYG A;  3IR7 A;  2JIO A;  4C2M A;  4KO8 A;  5FTN A;  4B8C D;  4Q5G A;  4RV0 A;  4YWM A;  4V19 6;  2M6O A;  1E5V A;  4JAE A;  4AN8 A;  2V0E A;  4TVM A;  4EJ3 A;  1TWF A;  2Y0N A;  1AW8 B;  3HKZ A;  3IAY A;  2K3Q A;  2V0F A;  1RB9 A;  4AR3 A;  1PQE A;  1LPQ A;  4ME3 A;  2PVX A;  4AHW A;  1VZI A;  3K5O A;  4KB4 A;  1K4S A;  1A35 A;  1WCM A;  2LPI A;  4KAW X;  1IRO A;  4POG A;  2G6G A;  1I3Q A;  3LRD A;  2JA7 A;  1R7R A;  4AI2 A;  3GTJ A;  3QQC E;  5MLC 3;  3MAQ A;  4D7Z B;  1YNN D;  1BFY A;  3PIO 1;  3IR6 A;  2MS3 A;  1I50 A;  1Y69 8;  1PPY A;  4KDL A;  1TWA A;  2CR8 A;  2GMG A;  3LF9 A;  2R7Z A;  1Q8I A;  1IRN A;  1NNQ A;  4NOH A;  2E7Z A;  1IU6 A;  1E61 A;  4NOK A;  3LPE B;  2AE0 X;  1R0G A;  2BE5 D;  2JA6 A;  2ERS A;  5CQG A;  4AAY A;  1A36 A;  2F4Q A;  1UHE A;  5GAD c;  1B2O A;  1DD5 A;  2CKA A;  3QQ8 A;  3PKI A;  4K9F A;  3DU6 A;  1RRJ A;  4H3T A;  1CR5 A;  1RR8 C;  4ZN1 B;  1SFO A;  3OUG A;  1R0F A;  1VC3 B;  3VPB E;  5MLC 9;  2VK9 A;  2JIR A;  1VCX A;  3FKI A;  3RZT A;  5K2M E;  4POF A;  4L8I A;  4ZN3 B;  1WQG A;  3K5N A;  3PWF A;  1OWB A;  2V3V A;  4NOM A;  2DSX A;  1A31 A;  2HR5 A;  2NYA A;  6RXN A;  1QCS A;  3QQ7 A;  1CZ4 A;  3B08 B;  1YNJ D;  2RDV A;  2L0Z A;  1T8I A;  5IY0 A;  5MFZ A;  5RXN A;  4LMO A;  3GTP A;  2V45 A;  1IW7 D;  2PSM C;  3O5A A;  3CQZ A;  1BQ8 A;  1Y1V A;  3J7Z 1;  1B2J A;  1PYQ A;  1S2Z A;  3ZG6 A;  1DMR A;  2JI1 A;  2E2I A;  2JI2 A;  2NVX A;  4KC6 A;  5JSN B;  3U4Q A;  3WWN B;  5MFP A;  4CS0 A;  2ZIX A;  4UY8 1;  2H12 A;  4FYD A;  1YV1 A;  4RXN A;  2Z3R B;  1R9T A;  4AI1 A;  1DMS A;  1Y1W A;  2B5I D;  1I6V D;  3B0A B;  1E18 A;  2PMZ A;  5GAH c;  1PYU B;  2Y0S A;  3K58 A;  5C9H A;  1TGO A;  2M4V A;  2ERJ A;  1IS1 A;  5C1B A;  2XJQ A;  3DU5 A;  1EU1 A;  4DMR A;  3KYL A;  2KKD A;  5AI3 A;  8RXN A;  2V3B B;  3U44 A;  3H0G A;  1RDV A;  1WJV A;  1KQF A;  4JLR C;  2B9S B;  4G6B A;  2N1D B;  1GE9 A;  1R0J A;  1WQH A;  2K3O A;  3GTG A;  2LTH A;  4IP9 A;  2IV2 X;  1RYT A;  1ZC1 A;  4AYB A;  1WQF A;  2XJU A;  1E32 A;  1TMO A;  2NVY A;  2PNW A;  5EPP A;  3IU3 I;  7RXN A;  1S24 A;  1TWH A;  1T9Q A;  3IR5 A;  1AA6 A;  1C09 A;  2M6P A;  1IU5 A;  2VPZ A;  1SC7 A;  2YU9 A;  2R93 A;  2JI3 A;  5FTK A;  5DYI A;  1S30 A;  3QC8 A;  2X0O A;  5AI2 A;  2XJS A;  1VZH A;  2MX8 A;  4GS7 D;  1H5N A;  2JIP A;  3HU2 A;  2PJH B;  3WVO A;  2O5J D;  1OWC A;  2NYD A;  3GTM A;  4AHZ A;  2NAP A;  2CW0 D;  1PT0 A;  4KDD A;  3WWL A;  5JVH 1;  3NFP I;  1FHM A;  3LHP S;  1PQH A;  2PIC A;  4AR6 A;  1G8J A;  2J9U B;  2C45 A;  4AR4 A;  1CZ5 A;  5EIO C;  2VPY A;  5JVG 1;  3LR2 A;  1H0H A;  4D3Y A;  2F5J A;  4O26 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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