1HQMA

Crystal structure of thermus aquaticus core rna polymerase-includes complete structure with side-chains (except for disordered regions)-further refined from original deposition-contains additional sequence information
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
223
structure length
223
Chain Sequence
LKAPVFTATTQGDHYGEFVLEPLERGFGVTLGNPLRRILLSSIPGTAVTSVYIEDVLHEFSTIPGVKEDVVEIILNLKELVVRFLDPRWRTTLILRAEGPKEVRAVDFTPSADVEIMNPDLHIATLEEGGKLYMEVRVDRGVGYVPAERHGIKDRINAIPVDAIFSPVRRVAFQVEDTRLGQRTDLDKLTLRIWTDGSVTPLEALNQAVAILKEHLNYFANPE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly.
pubmed doi rcsb
molecule tags Transferase
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 31
structure length 223
sequence length 223
chains with identical sequence B
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2000-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
A PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
A PF03118 RNA_pol_A_CTD Bacterial RNA polymerase, alpha chain C terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 1hqmA02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 1hqmA01
4C2MC 5IYCC 2NVQC 2A6HA 1TWHC 2R93C 4A3IC 2PA8D 1YNJA 2Y0SD 5C4JC 1SFOC 2R92C 2VUMK 2A68A 1IW7A 2B63C 4LLGA 4BY1C 2A6EA 4LK1A 4BBSC 3FKIK 4QJVB 5IYBK 4KN7A 2JA5K 3HOZK 4A3LK 4A3GC 4G7HA 1R9TK 2JA7C 3S2HC 3H3VL 1I3QC 2E2HC 1WCMC 3GTQK 3CQZC 3EQLA 5IP7C 4A3EC 4A3BC 4OIRA 1BDFA 2E2JK 2CW0A 4MQ9A 2BE5A 3GTLC 5TMCA 3H3VD 1K83K 2NVTK 4BY7K 5C44C 3GTOC 4XSZA 3S1RK 3PO3C 4MEXA 2JA8C 4JK1A 5M3FK 5C4XK 1Y1VK 4OINA 4A3CK 2NVYC 1TWFK 1YNNA 3M4OC 3RZDC 1HQMA 3HOXK 3HOUC 4X6AC 3HOYK 1TWCK 3GTKK 1I50C 4XLNA 2E2IK 3DXJA 4KN4A 1TWGK 3S2DK 2NVXC 4Y7NC 3GTMK 4Y52C 1XPPA 3I4MK 4GZYA 4LK0A 5IYDK 2YU9C 3GTGC 1Y1WC 2R7ZC 3S14C 3S17K 2PPBA 3HOWC 5FLMC 1TWAK 3GTJC 3GTPK 5IP9C 4XLPA 3S1QK 4OIQA 4YFXA 4A3MC 3GTQC 4C3JC 3S15C 2JA6K 4BBRK 4C3IC 4G7ZA 5M5XK 4A3JK 3I4NK 4C2MK 5IYCK 2NVQK 4LJZA 2O5IA 3S16K 3PO2C 1TWHK 2R93K 4A3FK 4QIWL 4A3IK 5C4JK 1SFOK 3WODA 2PMZL 3S1NK 4BY1K 1I6VA 2NVTC 4A3DC 4C3HK 5M5WK 3RZOC 3S1MC 4A3GK 3H0GC 4A93C 4QIWD 3M3YC 3S2HK 1I3QK 5C3EC 2PMZD 1Y1VC 3HOVC 3CQZK 4BXXC 1TWFC 1I6HC 4YG2A 4G7OA 4OIOA 3HOXC 4A3EK 4A3BK 4AYBL 3GTKC 4A3KC 4OIPA 3GTLK 2WAQL 4YFKA 3K7AK 4XSXA 5C44K 3GTOK 2VUMC 3I4MC 3PO3K 3S17C 3FKIC 5IYBC 2JA8K 4YFNA 1ZYRA 4AYBD 2JA5C 4ZH4A 3HOZC 4A3LC 2NVYK 2WAQD 4MEYA 3RZDK 2O5JA 3M4OK 3HOUK 1R9TC 4X6AK 3S1QC 4Q5SA 1I50K 1SMYA 2NVXK 4Q4ZA 2JA6C 4Y52K 2R92K 2YU9K 5D4DA 2B63K 3GTGK 4A3JC 2R7ZK 3S14K 2E2JC 4BBSK 3HOWK 5FLMK 3S16C 1K83C 4BY7C 4A3FC 3S1RC 3GTJK 5IP9K 4QJVA 2JA7K 3S1NC 4A3MK 2E2HK 1WCMK 4C3HC 5C4XC 4KMUA 5TMFA 3HKZL 4A3CC 4C3JK 3S15K 2WB1L 5IP7K 4C3IK 4NOIA 3HOYC 1TWCC 2E2IC 1TWGC 3S2DC 3GTMC 3PO2K 5FJ8K 3HKZD 2WB1D 5IYDC 4A3DK 3K7AC 3RZOK 3S1MK 1TWAC 4A3KK 3H0GK 3GTPC 5M3MK 3M3YK 4A93K 5C3EK 5M5YK 3HOVK 2PA8L 4Y7NK 2Y0SL 4BXXK 1I6HK 4BBRC 2A69A 1Y1WK 3I4NC
chains in the Genus database with same CATH superfamily
4C2MC 4WF9S 4WFNS 2NVQC 2JH3A 1TWHC 2VUMK 2Y0SD 1SFOC 2B63C 4PABA 4LLGA 4BY1C 4BBSC 3FKIK 4QJVB 2ZJRS 4KN7A 2E2HC 1BGWA 1ISEA 3ERED 3CQZA 4A3BC 5IOQA 2XCQA 5JVOA 5CHPA 2CW0A 4MQ9A 3GTLC 2NVTK 1K83K 2D6FC 3PO3C 4MEXA 4JK1A 5TJ3A 5C4XK 4M1XA 5M3FK 1TWFK 3RZDC 3AQOA 2NVYA 3HOXK 1PJ5A 4X6AC 4KN4A 2ZFZA 1USOA 1I50A 2NVXA 3I4MK 2R7ZC 2R92A 2YU9A 3LYWA 1IL2A 4XLPA 3S1QK 1WORA 5IOTA 3GTQC 4KDDA 1B4BA 3FHZA 1WCMA 1ZXOA 4C3IC 4BKWA 5M5XK 1EI6A 4C2MK 5EGHA 1EK8A 3QX3A 3VA7A 2NVQK 1TWHK 3NUHA 4QIWL 1SFOK 3G4CA 2PMZL 4BY1K 3TFIA 3RZOC 3S1MC 3CAGA 4WILA 3LAJA 1EH1A 4QIWD 3GSIA 3SZYA 4AH6A 3H0GA 2PMZD 3AD7C 4A3BK 5HL7S 4AYBL 3GTLK 1HI9A 4YFKA 2WAQL 3K7AK 4XSXA 2KQ1A 3PO3K 3S17C 4DDQA 4YFNA 2JA5C 4AYBD 4A3LC 1RU0A 2CFAA 3FKIA 2WAQD 1IE0A 3FOFA 2O5JA 3RZDK 4X6AK 2KPUA 2JA6C 5D4DA 2R7ZK 1J6WA 2W7VA 1K83A 3S1NC 3GTQK 1FEUA 3N3YA 2WB1L 4C3IK 1TWFA 3HOYC 3N0BA 2PHCB 2WB1D 5IYDC 3RZOK 3S1MK 4WFBS 5M3MK 1XXCA 3TTGA 5M5YK 4GTBA 1G51A 3TFJA 2R93C 4A3IC 5C4JC 1SFOA 2A6EA 4LK1A 1VH2A 2JA5K 4A3LK 1PJ7A 2V6SA 2JA7C 4KMDA 3PIPS 1J98A 2FQTA 2Y3PA 1O28A 5IP7C 2L5NA 2GAGC 5HQHA 3GIRA 5CJ9A 2BE5A 1BS2A 1O29A 5C44C 3GTOC 1WOOA 4KAWX 1Y1VK 1HQMA 3HOYK 3HOUC 1DD5A 4XLNA 4C45A 4GTEA 5DM6S 1O26A 4GZYA 1IQ0A 3S0XA 5IYDK 4GTDA 4LOWA 3GTGC 1Y1WC 2PPBA 3HOWC 2R7ZA 3AD9C 5FLMC 3G4AA 3GTJC 3N0CA 4A3MC 1I3QA 3S15C 3BUEA 3GTQA 4G7ZA 1F93A 2ZUEA 2ZUFA 2O5IA 1X31C 2R93K 4A3IK 5C4JK 3WODA 3TFHA 1I6VA 1C0AA 4PAAA 1GE9A 3M3YC 2RH6A 1YCLA 1I6HC 4G7OA 3GTKC 4A3KC 5C44K 3LAPA 3GTOK 2V6UA 1F7VA 5E68A 5IYBC 3HOZC 1ZYRA 4KASA 4ZH4A 1F7UA 2P8TA 1XZPB 2JA5A 4MEYA 1VGXA 3HOUK 1R9TC 1IBAA 1SMYA 3PIOS 4KMAA 2B63K 3GTGK 4A3JC 4BBSK 2E2JC 3HOWK 5FLMK 3S16C 4IO9S 3GEIA 4A3FC 3GTJK 1XZQB 4A3MK 2E2HK 4C3HC 3S15K 3HKZL 1Y1VA 3SZZA 3ADAC 1WQHA 1TWGC 2EBBA 5FJ8K 3HKZD 2VUMA 3MMLB 1XXAA 1TWAC 1WIHA 2ZJQS 3GTPC 3M3YK 4KC6A 4G0WA 1WQFA 4KB4A 2PA8L 1I6HK 4BBRC 4GTFA 4RMFA 3I4NC 4A3KK 5IYCC 2A6HA 4BLBA 2PA8D 2R92C 2R93A 1IW7A 5IYBK 2GSUA 3HOZK 1O2AA 1R9TK 4KARA 3AH5A 1WCMC 4WFAS 3L4JA 2GSNA 1BDFA 2E2JK 1F9NA 5TMCA 4XSZA 1O2FB 3OEPA 3GTOA 5EGEA 1XXBA 4LR2A 3V4GA 1YNNA 3M4OC 3Q3QA 4G0UA 3DXJA 1TWGK 5IOSA 1KQ4A 2KXYA 4Y7NC 4KATA 1XPPA 1TWHA 3S17K 3S14C 3GTGA 2B63A 1TWAK 1VJEA 3IPJA 3GTPK 4IOCS 5IP9C 1AB4A 3GTJA 1EFWA 2E2HA 2JA6K 4BBRK 3I4NK 5DM7S 4WCES 1WOSA 5IYCK 4LJZA 3GTLA 3T00A 3S1NK 1O24A 2NVTC 4A3DC 2GAHC 3A8KA 4A93C 1JQWA 5C3EC 3LPXA 3CF5S 4BXXC 1TWFC 4YG2A 3HOXC 4O2DA 4OIPA 1ZVUA 2XCRB 3I4MC 1PJ6A 3M4OK 4GT9A 3S1QC 1R9TA 1DCPA 4Q4ZA 1JVIA 3S14K 3GEHA 4BLAA 4BY7C 4GTAA 3S1RC 4XCHA 5IP9K 4QJVA 2JA7K 5TMFA 4KMHA 4A3CC 2GSOA 5IP7K 3HXAA 4NOIA 1O25A 1TWCC 2E2IC 3OREA 3S2DC 3GTMC 2P5MA 1TWGA 5L46A 2RGRA 4IOAS 1WOPA 4A3DK 3K7AC 2V6TA 1VLOA 4A93K 1TWAA 5C3EK 3GTPA 4BXXK 2A69A 2JA6A 5JVHS 1Y1WK 1O2BA 1YNJA 4FZBA 2A68A 3OPFA 3A8JA 4A3GC 4G7HA 3S2HC 3DLLS 3H3VL 1I3QC 1XZPA 3CQZC 3EQLA 2ZJPS 1IS1A 1INNA 4A3EC 1JOEA 4OIRA 4KB2A 2L3UA 2KWAA 3H3VD 4BY7K 3FOEA 2CFAB 3S1RK 1J6XA 4GTLA 2JA8C 1ZBSA 1L0WA 4OINA 4LQYA 4A3CK 2NVYC 1XZQA 3JSTA 4G0VA 1TWCK 3GTKK 1I50C 1B4AA 3T02A 2E2IK 3S2DK 2NVXC 3GTMK 4Y52C 4LK0A 2YU9C 1J6VA 4U67S 4OIQA 4YFXA 2JA7A 4C3JC 1WQGA 4KM9A 4A3JK 3S16K 3PO2C 4A3FK 3GEEA 5JFEA 4C3HK 5M5WK 4A3GK 3H0GC 3BP3A 3S2HK 1I3QK 1Y1VC 3HOVC 1BJTA 3CQZK 2FQOA 4P5BA 4OIOA 4A3EK 1ZQ1C 1Y1WA 3A8IA 4GTCA 1WSRA 4WJ4A 2VUMC 5HL8A 3FKIC 2JA8K 3GDZA 2NVYK 4FM9A 4ILDA 3T01A 4Q5SA 1I50K 1UV7A 2NVXK 4Y52K 1WSVA 1O27A 2R92K 2YU9K 4KM8A 1DCHA 1K83C 4J3NA 1YX2A 5JVGS 1WCMK 5C4XC 4GFQA 4KMUA 4C3JK 3L4KA 4WJ3M 1V5VA 1TWCA 3GTKA 3AQPA 2E2IA 3PO2K 3GTMA 4P5AA 3AD8C 1EQRA 1DCOA 3H0GK 5IORA 2XCOA 3BP8C 3HOVK 4Y7NK 2Y0SL 4P9SA 1VRQC 1USMA
chains in the Genus database with same CATH topology
4C2MC 5IYCC 2NVQC 2A6HA 1TWHC 2R93C 4A3IC 2PA8D 1YNJA 2Y0SD 5C4JC 1SFOC 2R92C 2VUMK 2A68A 1IW7A 2B63C 4LLGA 4BY1C 2A6EA 4LK1A 4BBSC 3FKIK 4QJVB 5IYBK 4KN7A 2JA5K 3HOZK 4A3LK 4A3GC 4G7HA 1R9TK 2JA7C 3S2HC 3H3VL 1I3QC 2E2HC 1WCMC 3GTQK 3CQZC 3EQLA 5IP7C 4A3EC 4A3BC 4OIRA 1BDFA 2E2JK 2CW0A 4MQ9A 2BE5A 3GTLC 5TMCA 3H3VD 1K83K 2NVTK 4BY7K 5C44C 3GTOC 4XSZA 3S1RK 3PO3C 4MEXA 2JA8C 4JK1A 5M3FK 5C4XK 1Y1VK 4OINA 4A3CK 2NVYC 1TWFK 1YNNA 3M4OC 3RZDC 1HQMA 3HOXK 3HOUC 4X6AC 3HOYK 1TWCK 3GTKK 1I50C 4XLNA 2E2IK 3DXJA 4KN4A 1TWGK 3S2DK 2NVXC 4Y7NC 3GTMK 4Y52C 1XPPA 3I4MK 4GZYA 4LK0A 5IYDK 2YU9C 3GTGC 1Y1WC 2R7ZC 3S14C 3S17K 2PPBA 3HOWC 5FLMC 1TWAK 3GTJC 3GTPK 5IP9C 4XLPA 3S1QK 4OIQA 4YFXA 4A3MC 3GTQC 4C3JC 3S15C 2JA6K 4BBRK 4C3IC 4G7ZA 5M5XK 4A3JK 3I4NK 4C2MK 5IYCK 2NVQK 4LJZA 2O5IA 3S16K 3PO2C 1TWHK 2R93K 4A3FK 4QIWL 4A3IK 5C4JK 1SFOK 3WODA 2PMZL 3S1NK 4BY1K 1I6VA 2NVTC 4A3DC 4C3HK 5M5WK 3RZOC 3S1MC 4A3GK 3H0GC 4A93C 4QIWD 3M3YC 3S2HK 1I3QK 5C3EC 2PMZD 1Y1VC 3HOVC 3CQZK 4BXXC 1TWFC 1I6HC 4YG2A 4G7OA 4OIOA 3HOXC 4A3EK 4A3BK 4AYBL 3GTKC 4A3KC 4OIPA 3GTLK 2WAQL 4YFKA 3K7AK 4XSXA 5C44K 3GTOK 2VUMC 3I4MC 3PO3K 3S17C 3FKIC 5IYBC 2JA8K 4YFNA 1ZYRA 4AYBD 2JA5C 4ZH4A 3HOZC 4A3LC 2NVYK 2WAQD 4MEYA 3RZDK 2O5JA 3M4OK 3HOUK 1R9TC 4X6AK 3S1QC 4Q5SA 1I50K 1SMYA 2NVXK 4Q4ZA 2JA6C 4Y52K 2R92K 2YU9K 5D4DA 2B63K 3GTGK 4A3JC 2R7ZK 3S14K 2E2JC 4BBSK 3HOWK 5FLMK 3S16C 1K83C 4BY7C 4A3FC 3S1RC 3GTJK 5IP9K 4QJVA 2JA7K 3S1NC 4A3MK 2E2HK 1WCMK 4C3HC 5C4XC 4KMUA 5TMFA 3HKZL 4A3CC 4C3JK 3S15K 2WB1L 5IP7K 4C3IK 4NOIA 3HOYC 1TWCC 2E2IC 1TWGC 3S2DC 3GTMC 3PO2K 5FJ8K 3HKZD 2WB1D 5IYDC 4A3DK 3K7AC 3RZOK 3S1MK 1TWAC 4A3KK 3H0GK 3GTPC 5M3MK 3M3YK 4A93K 5C3EK 5M5YK 3HOVK 2PA8L 4Y7NK 2Y0SL 4BXXK 1I6HK 4BBRC 2A69A 1Y1WK 3I4NC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C2M C;  5IYC C;  2NVQ C;  2A6H A;  1TWH C;  2R93 C;  4A3I C;  2PA8 D;  1YNJ A;  2Y0S D;  5C4J C;  1SFO C;  2R92 C;  2VUM K;  2A68 A;  1IW7 A;  2B63 C;  4LLG A;  4BY1 C;  2A6E A;  4LK1 A;  4BBS C;  3FKI K;  4QJV B;  5IYB K;  4KN7 A;  2JA5 K;  3HOZ K;  4A3L K;  4A3G C;  4G7H A;  1R9T K;  2JA7 C;  3S2H C;  3H3V L;  1I3Q C;  2E2H C;  1WCM C;  3GTQ K;  3CQZ C;  3EQL A;  5IP7 C;  4A3E C;  4A3B C;  4OIR A;  1BDF A;  2E2J K;  2CW0 A;  4MQ9 A;  2BE5 A;  3GTL C;  5TMC A;  3H3V D;  1K83 K;  2NVT K;  4BY7 K;  5C44 C;  3GTO C;  4XSZ A;  3S1R K;  3PO3 C;  4MEX A;  2JA8 C;  4JK1 A;  5M3F K;  5C4X K;  1Y1V K;  4OIN A;  4A3C K;  2NVY C;  1TWF K;  1YNN A;  3M4O C;  3RZD C;  1HQM A;  3HOX K;  3HOU C;  4X6A C;  3HOY K;  1TWC K;  3GTK K;  1I50 C;  4XLN A;  2E2I K;  3DXJ A;  4KN4 A;  1TWG K;  3S2D K;  2NVX C;  4Y7N C;  3GTM K;  4Y52 C;  1XPP A;  3I4M K;  4GZY A;  4LK0 A;  5IYD K;  2YU9 C;  3GTG C;  1Y1W C;  2R7Z C;  3S14 C;  3S17 K;  2PPB A;  3HOW C;  5FLM C;  1TWA K;  3GTJ C;  3GTP K;  5IP9 C;  4XLP A;  3S1Q K;  4OIQ A;  4YFX A;  4A3M C;  3GTQ C;  4C3J C;  3S15 C;  2JA6 K;  4BBR K;  4C3I C;  4G7Z A;  5M5X K;  4A3J K;  3I4N K;  4C2M K;  5IYC K;  2NVQ K;  4LJZ A;  2O5I A;  3S16 K;  3PO2 C;  1TWH K;  2R93 K;  4A3F K;  4QIW L;  4A3I K;  5C4J K;  1SFO K;  3WOD A;  2PMZ L;  3S1N K;  4BY1 K;  1I6V A;  2NVT C;  4A3D C;  4C3H K;  5M5W K;  3RZO C;  3S1M C;  4A3G K;  3H0G C;  4A93 C;  4QIW D;  3M3Y C;  3S2H K;  1I3Q K;  5C3E C;  2PMZ D;  1Y1V C;  3HOV C;  3CQZ K;  4BXX C;  1TWF C;  1I6H C;  4YG2 A;  4G7O A;  4OIO A;  3HOX C;  4A3E K;  4A3B K;  4AYB L;  3GTK C;  4A3K C;  4OIP A;  3GTL K;  2WAQ L;  4YFK A;  3K7A K;  4XSX A;  5C44 K;  3GTO K;  2VUM C;  3I4M C;  3PO3 K;  3S17 C;  3FKI C;  5IYB C;  2JA8 K;  4YFN A;  1ZYR A;  4AYB D;  2JA5 C;  4ZH4 A;  3HOZ C;  4A3L C;  2NVY K;  2WAQ D;  4MEY A;  3RZD K;  2O5J A;  3M4O K;  3HOU K;  1R9T C;  4X6A K;  3S1Q C;  4Q5S A;  1I50 K;  1SMY A;  2NVX K;  4Q4Z A;  2JA6 C;  4Y52 K;  2R92 K;  2YU9 K;  5D4D A;  2B63 K;  3GTG K;  4A3J C;  2R7Z K;  3S14 K;  2E2J C;  4BBS K;  3HOW K;  5FLM K;  3S16 C;  1K83 C;  4BY7 C;  4A3F C;  3S1R C;  3GTJ K;  5IP9 K;  4QJV A;  2JA7 K;  3S1N C;  4A3M K;  2E2H K;  1WCM K;  4C3H C;  5C4X C;  4KMU A;  5TMF A;  3HKZ L;  4A3C C;  4C3J K;  3S15 K;  2WB1 L;  5IP7 K;  4C3I K;  4NOI A;  3HOY C;  1TWC C;  2E2I C;  1TWG C;  3S2D C;  3GTM C;  3PO2 K;  5FJ8 K;  3HKZ D;  2WB1 D;  5IYD C;  4A3D K;  3K7A C;  3RZO K;  3S1M K;  1TWA C;  4A3K K;  3H0G K;  3GTP C;  5M3M K;  3M3Y K;  4A93 K;  5C3E K;  5M5Y K;  3HOV K;  2PA8 L;  4Y7N K;  2Y0S L;  4BXX K;  1I6H K;  4BBR C;  2A69 A;  1Y1W K;  3I4N C; 
#chains in the Genus database with same CATH topology
 4C2M C;  4WF9 S;  4WFN S;  2NVQ C;  2JH3 A;  1TWH C;  2VUM K;  2Y0S D;  1SFO C;  2B63 C;  4PAB A;  4LLG A;  4BY1 C;  4BBS C;  3FKI K;  4QJV B;  2ZJR S;  4KN7 A;  2E2H C;  1BGW A;  1ISE A;  3ERE D;  3CQZ A;  4A3B C;  5IOQ A;  2XCQ A;  5JVO A;  5CHP A;  2CW0 A;  4MQ9 A;  3GTL C;  2NVT K;  1K83 K;  2D6F C;  3PO3 C;  4MEX A;  4JK1 A;  5TJ3 A;  5C4X K;  4M1X A;  5M3F K;  1TWF K;  3RZD C;  3AQO A;  2NVY A;  3HOX K;  1PJ5 A;  4X6A C;  4KN4 A;  2ZFZ A;  1USO A;  1I50 A;  2NVX A;  3I4M K;  2R7Z C;  2R92 A;  2YU9 A;  3LYW A;  1IL2 A;  4XLP A;  3S1Q K;  1WOR A;  5IOT A;  3GTQ C;  4KDD A;  1B4B A;  3FHZ A;  1WCM A;  1ZXO A;  4C3I C;  4BKW A;  5M5X K;  1EI6 A;  4C2M K;  5EGH A;  1EK8 A;  3QX3 A;  3VA7 A;  2NVQ K;  1TWH K;  3NUH A;  4QIW L;  1SFO K;  3G4C A;  2PMZ L;  4BY1 K;  3TFI A;  3RZO C;  3S1M C;  3CAG A;  4WIL A;  3LAJ A;  1EH1 A;  4QIW D;  3GSI A;  3SZY A;  4AH6 A;  3H0G A;  2PMZ D;  3AD7 C;  4A3B K;  5HL7 S;  4AYB L;  3GTL K;  1HI9 A;  4YFK A;  2WAQ L;  3K7A K;  4XSX A;  2KQ1 A;  3PO3 K;  3S17 C;  4DDQ A;  4YFN A;  2JA5 C;  4AYB D;  4A3L C;  1RU0 A;  2CFA A;  3FKI A;  2WAQ D;  1IE0 A;  3FOF A;  2O5J A;  3RZD K;  4X6A K;  2KPU A;  2JA6 C;  5D4D A;  2R7Z K;  1J6W A;  2W7V A;  1K83 A;  3S1N C;  3GTQ K;  1FEU A;  3N3Y A;  2WB1 L;  4C3I K;  1TWF A;  3HOY C;  3N0B A;  2PHC B;  2WB1 D;  5IYD C;  3RZO K;  3S1M K;  4WFB S;  5M3M K;  1XXC A;  3TTG A;  5M5Y K;  4GTB A;  1G51 A;  3TFJ A;  2R93 C;  4A3I C;  5C4J C;  1SFO A;  2A6E A;  4LK1 A;  1VH2 A;  2JA5 K;  4A3L K;  1PJ7 A;  2V6S A;  2JA7 C;  4KMD A;  3PIP S;  1J98 A;  2FQT A;  2Y3P A;  1O28 A;  5IP7 C;  2L5N A;  2GAG C;  5HQH A;  3GIR A;  5CJ9 A;  2BE5 A;  1BS2 A;  1O29 A;  5C44 C;  3GTO C;  1WOO A;  4KAW X;  1Y1V K;  1HQM A;  3HOY K;  3HOU C;  1DD5 A;  4XLN A;  4C45 A;  4GTE A;  5DM6 S;  1O26 A;  4GZY A;  1IQ0 A;  3S0X A;  5IYD K;  4GTD A;  4LOW A;  3GTG C;  1Y1W C;  2PPB A;  3HOW C;  2R7Z A;  3AD9 C;  5FLM C;  3G4A A;  3GTJ C;  3N0C A;  4A3M C;  1I3Q A;  3S15 C;  3BUE A;  3GTQ A;  4G7Z A;  1F93 A;  2ZUE A;  2ZUF A;  2O5I A;  1X31 C;  2R93 K;  4A3I K;  5C4J K;  3WOD A;  3TFH A;  1I6V A;  1C0A A;  4PAA A;  1GE9 A;  3M3Y C;  2RH6 A;  1YCL A;  1I6H C;  4G7O A;  3GTK C;  4A3K C;  5C44 K;  3LAP A;  3GTO K;  2V6U A;  1F7V A;  5E68 A;  5IYB C;  3HOZ C;  1ZYR A;  4KAS A;  4ZH4 A;  1F7U A;  2P8T A;  1XZP B;  2JA5 A;  4MEY A;  1VGX A;  3HOU K;  1R9T C;  1IBA A;  1SMY A;  3PIO S;  4KMA A;  2B63 K;  3GTG K;  4A3J C;  4BBS K;  2E2J C;  3HOW K;  5FLM K;  3S16 C;  4IO9 S;  3GEI A;  4A3F C;  3GTJ K;  1XZQ B;  4A3M K;  2E2H K;  4C3H C;  3S15 K;  3HKZ L;  1Y1V A;  3SZZ A;  3ADA C;  1WQH A;  1TWG C;  2EBB A;  5FJ8 K;  3HKZ D;  2VUM A;  3MML B;  1XXA A;  1TWA C;  1WIH A;  2ZJQ S;  3GTP C;  3M3Y K;  4KC6 A;  4G0W A;  1WQF A;  4KB4 A;  2PA8 L;  1I6H K;  4BBR C;  4GTF A;  4RMF A;  3I4N C;  4A3K K;  5IYC C;  2A6H A;  4BLB A;  2PA8 D;  2R92 C;  2R93 A;  1IW7 A;  5IYB K;  2GSU A;  3HOZ K;  1O2A A;  1R9T K;  4KAR A;  3AH5 A;  1WCM C;  4WFA S;  3L4J A;  2GSN A;  1BDF A;  2E2J K;  1F9N A;  5TMC A;  4XSZ A;  1O2F B;  3OEP A;  3GTO A;  5EGE A;  1XXB A;  4LR2 A;  3V4G A;  1YNN A;  3M4O C;  3Q3Q A;  4G0U A;  3DXJ A;  1TWG K;  5IOS A;  1KQ4 A;  2KXY A;  4Y7N C;  4KAT A;  1XPP A;  1TWH A;  3S17 K;  3S14 C;  3GTG A;  2B63 A;  1TWA K;  1VJE A;  3IPJ A;  3GTP K;  4IOC S;  5IP9 C;  1AB4 A;  3GTJ A;  1EFW A;  2E2H A;  2JA6 K;  4BBR K;  3I4N K;  5DM7 S;  4WCE S;  1WOS A;  5IYC K;  4LJZ A;  3GTL A;  3T00 A;  3S1N K;  1O24 A;  2NVT C;  4A3D C;  2GAH C;  3A8K A;  4A93 C;  1JQW A;  5C3E C;  3LPX A;  3CF5 S;  4BXX C;  1TWF C;  4YG2 A;  3HOX C;  4O2D A;  4OIP A;  1ZVU A;  2XCR B;  3I4M C;  1PJ6 A;  3M4O K;  4GT9 A;  3S1Q C;  1R9T A;  1DCP A;  4Q4Z A;  1JVI A;  3S14 K;  3GEH A;  4BLA A;  4BY7 C;  4GTA A;  3S1R C;  4XCH A;  5IP9 K;  4QJV A;  2JA7 K;  5TMF A;  4KMH A;  4A3C C;  2GSO A;  5IP7 K;  3HXA A;  4NOI A;  1O25 A;  1TWC C;  2E2I C;  3ORE A;  3S2D C;  3GTM C;  2P5M A;  1TWG A;  5L46 A;  2RGR A;  4IOA S;  1WOP A;  4A3D K;  3K7A C;  2V6T A;  1VLO A;  4A93 K;  1TWA A;  5C3E K;  3GTP A;  4BXX K;  2A69 A;  2JA6 A;  5JVH S;  1Y1W K;  1O2B A;  1YNJ A;  4FZB A;  2A68 A;  3OPF A;  3A8J A;  4A3G C;  4G7H A;  3S2H C;  3DLL S;  3H3V L;  1I3Q C;  1XZP A;  3CQZ C;  3EQL A;  2ZJP S;  1IS1 A;  1INN A;  4A3E C;  1JOE A;  4OIR A;  4KB2 A;  2L3U A;  2KWA A;  3H3V D;  4BY7 K;  3FOE A;  2CFA B;  3S1R K;  1J6X A;  4GTL A;  2JA8 C;  1ZBS A;  1L0W A;  4OIN A;  4LQY A;  4A3C K;  2NVY C;  1XZQ A;  3JST A;  4G0V A;  1TWC K;  3GTK K;  1I50 C;  1B4A A;  3T02 A;  2E2I K;  3S2D K;  2NVX C;  3GTM K;  4Y52 C;  4LK0 A;  2YU9 C;  1J6V A;  4U67 S;  4OIQ A;  4YFX A;  2JA7 A;  4C3J C;  1WQG A;  4KM9 A;  4A3J K;  3S16 K;  3PO2 C;  4A3F K;  3GEE A;  5JFE A;  4C3H K;  5M5W K;  4A3G K;  3H0G C;  3BP3 A;  3S2H K;  1I3Q K;  1Y1V C;  3HOV C;  1BJT A;  3CQZ K;  2FQO A;  4P5B A;  4OIO A;  4A3E K;  1ZQ1 C;  1Y1W A;  3A8I A;  4GTC A;  1WSR A;  4WJ4 A;  2VUM C;  5HL8 A;  3FKI C;  2JA8 K;  3GDZ A;  2NVY K;  4FM9 A;  4ILD A;  3T01 A;  4Q5S A;  1I50 K;  1UV7 A;  2NVX K;  4Y52 K;  1WSV A;  1O27 A;  2R92 K;  2YU9 K;  4KM8 A;  1DCH A;  1K83 C;  4J3N A;  1YX2 A;  5JVG S;  1WCM K;  5C4X C;  4GFQ A;  4KMU A;  4C3J K;  3L4K A;  4WJ3 M;  1V5V A;  1TWC A;  3GTK A;  3AQP A;  2E2I A;  3PO2 K;  3GTM A;  4P5A A;  3AD8 C;  1EQR A;  1DCO A;  3H0G K;  5IOR A;  2XCO A;  3BP8 C;  3HOV K;  4Y7N K;  2Y0S L;  4P9S A;  1VRQ C;  1USM A; 
#chains in the Genus database with same CATH homology
 4C2M C;  5IYC C;  2NVQ C;  2A6H A;  1TWH C;  2R93 C;  4A3I C;  2PA8 D;  1YNJ A;  2Y0S D;  5C4J C;  1SFO C;  2R92 C;  2VUM K;  2A68 A;  1IW7 A;  2B63 C;  4LLG A;  4BY1 C;  2A6E A;  4LK1 A;  4BBS C;  3FKI K;  4QJV B;  5IYB K;  4KN7 A;  2JA5 K;  3HOZ K;  4A3L K;  4A3G C;  4G7H A;  1R9T K;  2JA7 C;  3S2H C;  3H3V L;  1I3Q C;  2E2H C;  1WCM C;  3GTQ K;  3CQZ C;  3EQL A;  5IP7 C;  4A3E C;  4A3B C;  4OIR A;  1BDF A;  2E2J K;  2CW0 A;  4MQ9 A;  2BE5 A;  3GTL C;  5TMC A;  3H3V D;  1K83 K;  2NVT K;  4BY7 K;  5C44 C;  3GTO C;  4XSZ A;  3S1R K;  3PO3 C;  4MEX A;  2JA8 C;  4JK1 A;  5M3F K;  5C4X K;  1Y1V K;  4OIN A;  4A3C K;  2NVY C;  1TWF K;  1YNN A;  3M4O C;  3RZD C;  1HQM A;  3HOX K;  3HOU C;  4X6A C;  3HOY K;  1TWC K;  3GTK K;  1I50 C;  4XLN A;  2E2I K;  3DXJ A;  4KN4 A;  1TWG K;  3S2D K;  2NVX C;  4Y7N C;  3GTM K;  4Y52 C;  1XPP A;  3I4M K;  4GZY A;  4LK0 A;  5IYD K;  2YU9 C;  3GTG C;  1Y1W C;  2R7Z C;  3S14 C;  3S17 K;  2PPB A;  3HOW C;  5FLM C;  1TWA K;  3GTJ C;  3GTP K;  5IP9 C;  4XLP A;  3S1Q K;  4OIQ A;  4YFX A;  4A3M C;  3GTQ C;  4C3J C;  3S15 C;  2JA6 K;  4BBR K;  4C3I C;  4G7Z A;  5M5X K;  4A3J K;  3I4N K;  4C2M K;  5IYC K;  2NVQ K;  4LJZ A;  2O5I A;  3S16 K;  3PO2 C;  1TWH K;  2R93 K;  4A3F K;  4QIW L;  4A3I K;  5C4J K;  1SFO K;  3WOD A;  2PMZ L;  3S1N K;  4BY1 K;  1I6V A;  2NVT C;  4A3D C;  4C3H K;  5M5W K;  3RZO C;  3S1M C;  4A3G K;  3H0G C;  4A93 C;  4QIW D;  3M3Y C;  3S2H K;  1I3Q K;  5C3E C;  2PMZ D;  1Y1V C;  3HOV C;  3CQZ K;  4BXX C;  1TWF C;  1I6H C;  4YG2 A;  4G7O A;  4OIO A;  3HOX C;  4A3E K;  4A3B K;  4AYB L;  3GTK C;  4A3K C;  4OIP A;  3GTL K;  2WAQ L;  4YFK A;  3K7A K;  4XSX A;  5C44 K;  3GTO K;  2VUM C;  3I4M C;  3PO3 K;  3S17 C;  3FKI C;  5IYB C;  2JA8 K;  4YFN A;  1ZYR A;  4AYB D;  2JA5 C;  4ZH4 A;  3HOZ C;  4A3L C;  2NVY K;  2WAQ D;  4MEY A;  3RZD K;  2O5J A;  3M4O K;  3HOU K;  1R9T C;  4X6A K;  3S1Q C;  4Q5S A;  1I50 K;  1SMY A;  2NVX K;  4Q4Z A;  2JA6 C;  4Y52 K;  2R92 K;  2YU9 K;  5D4D A;  2B63 K;  3GTG K;  4A3J C;  2R7Z K;  3S14 K;  2E2J C;  4BBS K;  3HOW K;  5FLM K;  3S16 C;  1K83 C;  4BY7 C;  4A3F C;  3S1R C;  3GTJ K;  5IP9 K;  4QJV A;  2JA7 K;  3S1N C;  4A3M K;  2E2H K;  1WCM K;  4C3H C;  5C4X C;  4KMU A;  5TMF A;  3HKZ L;  4A3C C;  4C3J K;  3S15 K;  2WB1 L;  5IP7 K;  4C3I K;  4NOI A;  3HOY C;  1TWC C;  2E2I C;  1TWG C;  3S2D C;  3GTM C;  3PO2 K;  5FJ8 K;  3HKZ D;  2WB1 D;  5IYD C;  4A3D K;  3K7A C;  3RZO K;  3S1M K;  1TWA C;  4A3K K;  3H0G K;  3GTP C;  5M3M K;  3M3Y K;  4A93 K;  5C3E K;  5M5Y K;  3HOV K;  2PA8 L;  4Y7N K;  2Y0S L;  4BXX K;  1I6H K;  4BBR C;  2A69 A;  1Y1W K;  3I4N C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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