2A69A

Crystal structure of the t. thermophilus rna polymerase holoenzyme in complex with antibiotic rifapentin
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
229
structure length
229
Chain Sequence
MLDSKLKAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPLRRILLSSIPGTAVTSVYIEDVLHEFSTIPGVKEDVVEIILNLKELVVRFLNPSLQTVTLLLKAEGPKEVKARDFLPVADVEIMNPDLHIATLEEGGRLNMEVRVDRGVGYVPAEKHGIKDRINAIPVDAVFSPVRRVAFQVEDTRLGQRTDLDKLTLRIWTDGSVTPLEALNQAVEILREHLTYFSNPQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
publication title Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase alpha chain
total genus 40
structure length 229
sequence length 229
chains with identical sequence B, K, L
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2005-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
A PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
A PF03118 RNA_pol_A_CTD Bacterial RNA polymerase, alpha chain C terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 2a69A02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 2a69A01
4BBSC 2E2IC 2JA8K 5C4JK 4A3JC 3GTJK 3GTLK 5C3EK 2NVYK 4YFKA 4QIWD 4XSXA 4G7ZA 1K83C 3RZDC 3HKZL 3S1NK 1I50C 5C44C 3S2DC 2B63C 2YU9K 2NVTC 1R9TK 4BXXK 4A3FC 2A6EA 4BBRK 3S1QK 2JA6C 2WAQD 1HQMA 5IYCC 2JA5C 2E2HC 3S14C 3GTKC 3HOZC 4C3JK 5IYBK 4G7HA 3K7AK 1IW7A 1TWAK 4C3IK 1BDFA 2NVQC 4A3DC 4A3MK 3M3YK 4C3HC 1WCMK 3S15K 3M4OK 2PPBA 1Y1WC 5IP9K 4Y52C 1YNJA 4A3EC 2PA8L 2E2IK 2WB1D 2PA8D 2R92K 4A3CK 5FLMC 4A3GC 4A3BK 4C2MK 4LK1A 2JA7C 4A3LK 1ZYRA 3S17K 4OINA 3HOUC 4Q5SA 4QIWL 2R7ZK 3DXJA 2A69A 3FKIC 5IYDC 3EQLA 3HOYC 4YFNA 3H0GK 4LK0A 4A3FK 3HOWK 3RZOK 4XLNA 4AYBD 3S1MK 2R93K 1I6HC 1TWHC 3CQZC 3S2HC 1I6VA 5IP7C 2CW0A 4Y7NC 1TWCK 2WAQL 3GTQC 1YNNA 2BE5A 4A3IK 2NVQK 4ZH4A 2E2JC 1Y1VC 3GTOC 2Y0SL 5M3MK 4QJVA 1SFOK 3S1RC 4A93C 3S16C 2Y0SD 3HOXC 3I4MC 3I4NK 3HOVK 4A3KK 4X6AC 1SMYA 2VUMK 3GTMK 4BY7K 4G7OA 1TWGK 1XPPA 3GTGC 1TWFK 3PO2C 2WB1L 1I3QK 4BY1K 3HOYK 3GTPC 4BBSK 4MEXA 4A3JK 4JK1A 2NVXC 4YFXA 2JA8C 5C4JC 3RZDK 3GTJC 3GTLC 1K83K 5C3EC 2NVYC 5M5WK 2O5JA 1I50K 5C44K 3S2DK 3S1NC 2B63K 2A68A 4LJZA 4AYBL 2NVTK 2JA6K 2YU9C 1R9TC 4QJVB 5M5XK 4BBRC 2A6HA 3S1QC 3PO3C 4OIRA 5IYCK 2E2HK 2JA5K 3GTKK 3HOZK 3S14K 4KN4A 4Q4ZA 4A3DK 4OIOA 5FJ8K 5D4DA 4C3HK 4C3JC 5IYBC 3K7AC 4C3IC 1TWAC 4XLPA 4A3MC 3M3YC 1Y1WK 3H3VL 4Y52K 1WCMC 3S15C 3M4OC 4A3EK 3H3VD 5IP9C 5TMCA 3WODA 4YG2A 5FLMK 4A3GK 5M5YK 2JA7K 2PMZD 2R92C 3HOUK 4A3CC 5C4XC 4A3BC 4OIPA 4C2MC 4A3LC 4KMUA 3S17C 4NOIA 3FKIK 5IYDK 3HKZD 2R7ZC 3H0GC 3HOWC 3RZOC 3PO3K 5TMFA 1TWHK 3CQZK 5IP7K 3S2HK 1I6HK 4Y7NK 3S1MC 3GTQK 4BXXC 4XSZA 2R93C 2E2JK 4A3IC 1Y1VK 3GTOK 1TWCC 2O5IA 3S1RK 4OIQA 3S16K 4A93K 3HOXK 5M3FK 3I4MK 1SFOC 4LLGA 4MQ9A 4MEYA 4X6AK 3I4NC 3HOVC 4GZYA 3GTGK 3PO2K 4A3KC 4BY7C 3GTPK 2VUMC 3GTMC 5C4XK 4KN7A 1TWGC 2NVXK 2PMZL 1TWFC 1I3QC 4BY1C
chains in the Genus database with same CATH superfamily
4A3JC 3GTJK 3GTLK 1B4AA 3H0GA 4XSXA 3RZDC 1XZQA 3ERED 1WOPA 4A3FC 5JFEA 3S1QK 2PHCB 2R93A 4KAWX 1O27A 4KC6A 2JA5C 3S14C 4KMAA 1SFOA 4C3IK 1J6WA 4A3MK 2NVQC 1TWAA 2XCRB 4G0UA 4Y52C 4KB4A 3GDZA 3CAGA 2E2IA 4A3CK 4A3GC 4LK1A 2JA7C 1DCOA 4OINA 1PJ5A 2ZUFA 1XZPA 3DXJA 3FKIC 5HL7S 3EQLA 4A3FK 3GEEA 5JVHS 3S1MK 1I6VA 3L4KA 1YNNA 2NVQK 3MMLB 5M3MK 2P5MA 3VA7A 3IPJA 4WILA 3FOEA 4A3KK 3T01A 2ZJPS 4G7OA 3HOYK 3AH5A 4BBSK 1I3QA 4JK1A 3PIOS 2KWAA 2JA8C 5C4JC 5C3EC 1I50K 2B63K 1ZQ1C 4BKWA 2NVTK 1GE9A 3OPFA 1V5VA 1WQGA 1TWHA 2YU9C 4QJVB 5M5XK 2D6FC 2E2HK 2JA5A 4A3DK 5FJ8K 3K7AC 5L46A 1Y1WK 3M3YC 1WCMC 3M4OC 4A3EK 5DM7S 1XXCA 5IP9C 4PABA 1INNA 5M5YK 2NVXA 2JA7A 2R92C 1WSRA 1WQFA 1BS2A 3FKIA 3H0GC 3RZOC 3N0CA 2KXYA 1I6HK 3CQZK 3S2HK 4BXXC 2R93C 2E2JK 4A3IC 1Y1VK 1IL2A 2O5IA 3S1RK 3HOXK 4LQYA 1DCHA 1SFOC 1WSVA 2Y3PA 4GTAA 3I4NC 3GTGK 4P5AA 3LAPA 1TWGC 3FOFA 5IOTA 4BY1C 4KARA 2E2IC 4WF9S 1YCLA 3LYWA 3S1NK 1K83C 1J6XA 5C44C 1O24A 1ZVUA 3A8IA 4BXXK 1KQ4A 5HL8A 2YU9A 3N3YA 3GSIA 1TWCA 1HQMA 5IYCC 3BP8C 3S0XA 5HQHA 4C3JK 1TWAK 1BDFA 5CHPA 4C3HC 3ADAC 4GTEA 4KMHA 1YNJA 3GTMA 2KPUA 2PA8L 1TWFA 2E2IK 2WB1D 2R92A 4A3LK 1ZYRA 3HOUC 4YFNA 3HOWK 4LK0A 3G4CA 3AD9C 1O25A 1TWHC 2GSOA 4J3NA 5IP7C 1USOA 2CW0A 4G0WA 3GTKA 5EGHA 1WOSA 4A93C 3S16C 3HOVK 1F7UA 4WFBS 5EGEA 4X6AC 2WB1L 3PO2C 1TWGA 1I3QK 2FQOA 4A3JK 2NVXC 1RU0A 1EI6A 3RZDK 3L4JA 2NVYC 1K83A 5E68A 2W7VA 2A68A 5IOQA 1F9NA 1AB4A 1R9TC 4BBRC 2A6HA 3PO3C 2JA5K 3S14K 3GTOA 3GEHA 4KN4A 1O28A 1USMA 5IYBC 4FZBA 4Y52K 3H3VL 3NUHA 3S15C 2CFAA 3TFHA 4YG2A 4A3GK 3AD7C 2JA7K 1VJEA 3LAJA 3PIPS 3GIRA 3GTJA 4A3BC 3GTLA 4C2MC 2ZJRS 4KMUA 3S17C 5IOSA 3FKIK 4M1XA 3HKZD 3G4AA 2R7ZC 4ILDA 3JSTA 3PO3K 1I3QC 1O26A 4XSZA 2P8TA 1TWCC 3BUEA 5M3FK 5JVOA 4MEYA 1L0WA 4WJ3M 4BY7C 1IQ0A 2VUMC 3GTMC 2XCQA 5IORA 1TWFC 3FHZA 2ZJQS 1B4BA 2JA8K 5C4JK 5C3EK 4YFKA 3V4GA 2NVYA 4G7ZA 3HKZL 4IOCS 3S2DC 2JH3A 2YU9K 1R9TA 2JA6C 3GTKC 3HOZC 3LPXA 1EH1A 3K7AK 1IW7A 3M3YK 1WIHA 1WCMK 1F7VA 3M4OK 2PPBA 1XXAA 4AH6A 3HXAA 5IP9K 2PA8D 2R92K 5FLMC 4IO9S 1XZQB 4Q5SA 3H0GK 5IYDC 2R7ZA 3RZOK 3QX3A 2R93K 1EFWA 4A3IK 4Y7NC 2E2HA 3GTQC 2BE5A 3TTGA 4ZH4A 3GTOC 1O2AA 2Y0SL 4QJVA 1SFOK 1Y1WA 3I4MC 3I4NK 4WJ4A 2L5NA 3GEIA 1TWGK 1XPPA 3OEPA 2VUMA 1XZPB 4BY1K 3GTPC 3BP3A 2V6SA 5TJ3A 3GTJC 3GTLC 1K83K 5M5WK 1PJ6A 5C44K 5DM6S 1PJ7A 3CQZA 1J6VA 2JA6A 3S1QC 4GTFA 5IYCK 5CJ9A 2CFAB 1FEUA 1BGWA 5D4DA 4C3HK 4C3IC 4XLPA 4A3MC 1F93A 1EK8A 2EBBA 3TFIA 3H3VD 5TMCA 1EQRA 4KASA 3HOUK 4A3CC 5C4XC 4OIPA 2GSNA 1VGXA 4GTDA 1JQWA 2GAGC 1VRQC 5TMFA 1TWHK 4C45A 5IP7K 3S1MC 3GTQA 4P9SA 4A93K 3S16K 1C0AA 4X6AK 4GZYA 3PO2K 4A3KC 2ZUEA 3T02A 1O2FB 5C4XK 4FM9A 4KN7A 1VH2A 1BJTA 2NVXK 3GTPA 3HOYC 4BBSC 1ZBSA 4KDDA 2NVYK 1DCPA 4QIWD 2RGRA 4G0VA 1I50C 4KATA 3SZZA 2GSUA 2B63C 4BLAA 2NVTC 1R9TK 4BBRK 2A6EA 2WAQD 1XXBA 4LR2A 2E2HC 1WOOA 5IYBK 4G7HA 1IBAA 4WCES 4A3DC 4GTBA 4KM9A 4DDQA 3AD8C 3S15K 1Y1WC 1VLOA 4A3EC 1JVIA 3Q3QA 4KB2A 1ISEA 4A3BK 4C2MK 3A8JA 1IE0A 4KMDA 3S17K 2KQ1A 4QIWL 2R7ZK 2A69A 4XLNA 4AYBD 4BLBA 4GTLA 1ZXOA 1I6HC 3CQZC 3S2HC 1TWCK 2WAQL 2V6UA 2E2JC 4GT9A 1Y1VC 3S1RC 1DD5A 4U67S 2Y0SD 3HOXC 4BY7K 1SMYA 2VUMK 3GTMK 3GTGC 1TWFK 2GAHC 4MEXA 3SZYA 4YFXA 3N0BA 3T00A 4KM8A 2O5JA 4WFNS 5JVGS 1I50A 3S1NC 3S2DK 4LJZA 4AYBL 1G51A 2B63A 3OREA 1HI9A 2JA6K 4RMFA 3A8KA 3AQOA 4OIRA 3GTKK 3HOZK 4Q4ZA 1X31C 4OIOA 4C3JC 1TWAC 2L3UA 1O2BA 3WODA 2RH6A 4GTCA 1O29A 5FLMK 4P5BA 2ZFZA 4WFAS 2PMZD 4XCHA 1J98A 2XCOA 4A3LC 3AQPA 4NOIA 5IYDK 4IOAS 3CF5S 3TFJA 3HOWC 2V6TA 1YX2A 1UV7A 4Y7NK 1WQHA 3GTQK 1JOEA 1WORA 3GTOK 1Y1VA 4OIQA 4O2DA 1IS1A 4GFQA 3I4MK 1WCMA 4LLGA 3DLLS 4LOWA 4MQ9A 3HOVC 4PAAA 3GTGA 3GTPK 2PMZL 2FQTA
chains in the Genus database with same CATH topology
4BBSC 2E2IC 2JA8K 5C4JK 4A3JC 3GTJK 3GTLK 5C3EK 2NVYK 4YFKA 4QIWD 4XSXA 4G7ZA 1K83C 3RZDC 3HKZL 3S1NK 1I50C 5C44C 3S2DC 2B63C 2YU9K 2NVTC 1R9TK 4BXXK 4A3FC 2A6EA 4BBRK 3S1QK 2JA6C 2WAQD 1HQMA 5IYCC 2JA5C 2E2HC 3S14C 3GTKC 3HOZC 4C3JK 5IYBK 4G7HA 3K7AK 1IW7A 1TWAK 4C3IK 1BDFA 2NVQC 4A3DC 4A3MK 3M3YK 4C3HC 1WCMK 3S15K 3M4OK 2PPBA 1Y1WC 5IP9K 4Y52C 1YNJA 4A3EC 2PA8L 2E2IK 2WB1D 2PA8D 2R92K 4A3CK 5FLMC 4A3GC 4A3BK 4C2MK 4LK1A 2JA7C 4A3LK 1ZYRA 3S17K 4OINA 3HOUC 4Q5SA 4QIWL 2R7ZK 3DXJA 2A69A 3FKIC 5IYDC 3EQLA 3HOYC 4YFNA 3H0GK 4LK0A 4A3FK 3HOWK 3RZOK 4XLNA 4AYBD 3S1MK 2R93K 1I6HC 1TWHC 3CQZC 3S2HC 1I6VA 5IP7C 2CW0A 4Y7NC 1TWCK 2WAQL 3GTQC 1YNNA 2BE5A 4A3IK 2NVQK 4ZH4A 2E2JC 1Y1VC 3GTOC 2Y0SL 5M3MK 4QJVA 1SFOK 3S1RC 4A93C 3S16C 2Y0SD 3HOXC 3I4MC 3I4NK 3HOVK 4A3KK 4X6AC 1SMYA 2VUMK 3GTMK 4BY7K 4G7OA 1TWGK 1XPPA 3GTGC 1TWFK 3PO2C 2WB1L 1I3QK 4BY1K 3HOYK 3GTPC 4BBSK 4MEXA 4A3JK 4JK1A 2NVXC 4YFXA 2JA8C 5C4JC 3RZDK 3GTJC 3GTLC 1K83K 5C3EC 2NVYC 5M5WK 2O5JA 1I50K 5C44K 3S2DK 3S1NC 2B63K 2A68A 4LJZA 4AYBL 2NVTK 2JA6K 2YU9C 1R9TC 4QJVB 5M5XK 4BBRC 2A6HA 3S1QC 3PO3C 4OIRA 5IYCK 2E2HK 2JA5K 3GTKK 3HOZK 3S14K 4KN4A 4Q4ZA 4A3DK 4OIOA 5FJ8K 5D4DA 4C3HK 4C3JC 5IYBC 3K7AC 4C3IC 1TWAC 4XLPA 4A3MC 3M3YC 1Y1WK 3H3VL 4Y52K 1WCMC 3S15C 3M4OC 4A3EK 3H3VD 5IP9C 5TMCA 3WODA 4YG2A 5FLMK 4A3GK 5M5YK 2JA7K 2PMZD 2R92C 3HOUK 4A3CC 5C4XC 4A3BC 4OIPA 4C2MC 4A3LC 4KMUA 3S17C 4NOIA 3FKIK 5IYDK 3HKZD 2R7ZC 3H0GC 3HOWC 3RZOC 3PO3K 5TMFA 1TWHK 3CQZK 5IP7K 3S2HK 1I6HK 4Y7NK 3S1MC 3GTQK 4BXXC 4XSZA 2R93C 2E2JK 4A3IC 1Y1VK 3GTOK 1TWCC 2O5IA 3S1RK 4OIQA 3S16K 4A93K 3HOXK 5M3FK 3I4MK 1SFOC 4LLGA 4MQ9A 4MEYA 4X6AK 3I4NC 3HOVC 4GZYA 3GTGK 3PO2K 4A3KC 4BY7C 3GTPK 2VUMC 3GTMC 5C4XK 4KN7A 1TWGC 2NVXK 2PMZL 1TWFC 1I3QC 4BY1C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BBS C;  2E2I C;  2JA8 K;  5C4J K;  4A3J C;  3GTJ K;  3GTL K;  5C3E K;  2NVY K;  4YFK A;  4QIW D;  4XSX A;  4G7Z A;  1K83 C;  3RZD C;  3HKZ L;  3S1N K;  1I50 C;  5C44 C;  3S2D C;  2B63 C;  2YU9 K;  2NVT C;  1R9T K;  4BXX K;  4A3F C;  2A6E A;  4BBR K;  3S1Q K;  2JA6 C;  2WAQ D;  1HQM A;  5IYC C;  2JA5 C;  2E2H C;  3S14 C;  3GTK C;  3HOZ C;  4C3J K;  5IYB K;  4G7H A;  3K7A K;  1IW7 A;  1TWA K;  4C3I K;  1BDF A;  2NVQ C;  4A3D C;  4A3M K;  3M3Y K;  4C3H C;  1WCM K;  3S15 K;  3M4O K;  2PPB A;  1Y1W C;  5IP9 K;  4Y52 C;  1YNJ A;  4A3E C;  2PA8 L;  2E2I K;  2WB1 D;  2PA8 D;  2R92 K;  4A3C K;  5FLM C;  4A3G C;  4A3B K;  4C2M K;  4LK1 A;  2JA7 C;  4A3L K;  1ZYR A;  3S17 K;  4OIN A;  3HOU C;  4Q5S A;  4QIW L;  2R7Z K;  3DXJ A;  2A69 A;  3FKI C;  5IYD C;  3EQL A;  3HOY C;  4YFN A;  3H0G K;  4LK0 A;  4A3F K;  3HOW K;  3RZO K;  4XLN A;  4AYB D;  3S1M K;  2R93 K;  1I6H C;  1TWH C;  3CQZ C;  3S2H C;  1I6V A;  5IP7 C;  2CW0 A;  4Y7N C;  1TWC K;  2WAQ L;  3GTQ C;  1YNN A;  2BE5 A;  4A3I K;  2NVQ K;  4ZH4 A;  2E2J C;  1Y1V C;  3GTO C;  2Y0S L;  5M3M K;  4QJV A;  1SFO K;  3S1R C;  4A93 C;  3S16 C;  2Y0S D;  3HOX C;  3I4M C;  3I4N K;  3HOV K;  4A3K K;  4X6A C;  1SMY A;  2VUM K;  3GTM K;  4BY7 K;  4G7O A;  1TWG K;  1XPP A;  3GTG C;  1TWF K;  3PO2 C;  2WB1 L;  1I3Q K;  4BY1 K;  3HOY K;  3GTP C;  4BBS K;  4MEX A;  4A3J K;  4JK1 A;  2NVX C;  4YFX A;  2JA8 C;  5C4J C;  3RZD K;  3GTJ C;  3GTL C;  1K83 K;  5C3E C;  2NVY C;  5M5W K;  2O5J A;  1I50 K;  5C44 K;  3S2D K;  3S1N C;  2B63 K;  2A68 A;  4LJZ A;  4AYB L;  2NVT K;  2JA6 K;  2YU9 C;  1R9T C;  4QJV B;  5M5X K;  4BBR C;  2A6H A;  3S1Q C;  3PO3 C;  4OIR A;  5IYC K;  2E2H K;  2JA5 K;  3GTK K;  3HOZ K;  3S14 K;  4KN4 A;  4Q4Z A;  4A3D K;  4OIO A;  5FJ8 K;  5D4D A;  4C3H K;  4C3J C;  5IYB C;  3K7A C;  4C3I C;  1TWA C;  4XLP A;  4A3M C;  3M3Y C;  1Y1W K;  3H3V L;  4Y52 K;  1WCM C;  3S15 C;  3M4O C;  4A3E K;  3H3V D;  5IP9 C;  5TMC A;  3WOD A;  4YG2 A;  5FLM K;  4A3G K;  5M5Y K;  2JA7 K;  2PMZ D;  2R92 C;  3HOU K;  4A3C C;  5C4X C;  4A3B C;  4OIP A;  4C2M C;  4A3L C;  4KMU A;  3S17 C;  4NOI A;  3FKI K;  5IYD K;  3HKZ D;  2R7Z C;  3H0G C;  3HOW C;  3RZO C;  3PO3 K;  5TMF A;  1TWH K;  3CQZ K;  5IP7 K;  3S2H K;  1I6H K;  4Y7N K;  3S1M C;  3GTQ K;  4BXX C;  4XSZ A;  2R93 C;  2E2J K;  4A3I C;  1Y1V K;  3GTO K;  1TWC C;  2O5I A;  3S1R K;  4OIQ A;  3S16 K;  4A93 K;  3HOX K;  5M3F K;  3I4M K;  1SFO C;  4LLG A;  4MQ9 A;  4MEY A;  4X6A K;  3I4N C;  3HOV C;  4GZY A;  3GTG K;  3PO2 K;  4A3K C;  4BY7 C;  3GTP K;  2VUM C;  3GTM C;  5C4X K;  4KN7 A;  1TWG C;  2NVX K;  2PMZ L;  1TWF C;  1I3Q C;  4BY1 C; 
#chains in the Genus database with same CATH topology
 4A3J C;  3GTJ K;  3GTL K;  1B4A A;  3H0G A;  4XSX A;  3RZD C;  1XZQ A;  3ERE D;  1WOP A;  4A3F C;  5JFE A;  3S1Q K;  2PHC B;  2R93 A;  4KAW X;  1O27 A;  4KC6 A;  2JA5 C;  3S14 C;  4KMA A;  1SFO A;  4C3I K;  1J6W A;  4A3M K;  2NVQ C;  1TWA A;  2XCR B;  4G0U A;  4Y52 C;  4KB4 A;  3GDZ A;  3CAG A;  2E2I A;  4A3C K;  4A3G C;  4LK1 A;  2JA7 C;  1DCO A;  4OIN A;  1PJ5 A;  2ZUF A;  1XZP A;  3DXJ A;  3FKI C;  5HL7 S;  3EQL A;  4A3F K;  3GEE A;  5JVH S;  3S1M K;  1I6V A;  3L4K A;  1YNN A;  2NVQ K;  3MML B;  5M3M K;  2P5M A;  3VA7 A;  3IPJ A;  4WIL A;  3FOE A;  4A3K K;  3T01 A;  2ZJP S;  4G7O A;  3HOY K;  3AH5 A;  4BBS K;  1I3Q A;  4JK1 A;  3PIO S;  2KWA A;  2JA8 C;  5C4J C;  5C3E C;  1I50 K;  2B63 K;  1ZQ1 C;  4BKW A;  2NVT K;  1GE9 A;  3OPF A;  1V5V A;  1WQG A;  1TWH A;  2YU9 C;  4QJV B;  5M5X K;  2D6F C;  2E2H K;  2JA5 A;  4A3D K;  5FJ8 K;  3K7A C;  5L46 A;  1Y1W K;  3M3Y C;  1WCM C;  3M4O C;  4A3E K;  5DM7 S;  1XXC A;  5IP9 C;  4PAB A;  1INN A;  5M5Y K;  2NVX A;  2JA7 A;  2R92 C;  1WSR A;  1WQF A;  1BS2 A;  3FKI A;  3H0G C;  3RZO C;  3N0C A;  2KXY A;  1I6H K;  3CQZ K;  3S2H K;  4BXX C;  2R93 C;  2E2J K;  4A3I C;  1Y1V K;  1IL2 A;  2O5I A;  3S1R K;  3HOX K;  4LQY A;  1DCH A;  1SFO C;  1WSV A;  2Y3P A;  4GTA A;  3I4N C;  3GTG K;  4P5A A;  3LAP A;  1TWG C;  3FOF A;  5IOT A;  4BY1 C;  4KAR A;  2E2I C;  4WF9 S;  1YCL A;  3LYW A;  3S1N K;  1K83 C;  1J6X A;  5C44 C;  1O24 A;  1ZVU A;  3A8I A;  4BXX K;  1KQ4 A;  5HL8 A;  2YU9 A;  3N3Y A;  3GSI A;  1TWC A;  1HQM A;  5IYC C;  3BP8 C;  3S0X A;  5HQH A;  4C3J K;  1TWA K;  1BDF A;  5CHP A;  4C3H C;  3ADA C;  4GTE A;  4KMH A;  1YNJ A;  3GTM A;  2KPU A;  2PA8 L;  1TWF A;  2E2I K;  2WB1 D;  2R92 A;  4A3L K;  1ZYR A;  3HOU C;  4YFN A;  3HOW K;  4LK0 A;  3G4C A;  3AD9 C;  1O25 A;  1TWH C;  2GSO A;  4J3N A;  5IP7 C;  1USO A;  2CW0 A;  4G0W A;  3GTK A;  5EGH A;  1WOS A;  4A93 C;  3S16 C;  3HOV K;  1F7U A;  4WFB S;  5EGE A;  4X6A C;  2WB1 L;  3PO2 C;  1TWG A;  1I3Q K;  2FQO A;  4A3J K;  2NVX C;  1RU0 A;  1EI6 A;  3RZD K;  3L4J A;  2NVY C;  1K83 A;  5E68 A;  2W7V A;  2A68 A;  5IOQ A;  1F9N A;  1AB4 A;  1R9T C;  4BBR C;  2A6H A;  3PO3 C;  2JA5 K;  3S14 K;  3GTO A;  3GEH A;  4KN4 A;  1O28 A;  1USM A;  5IYB C;  4FZB A;  4Y52 K;  3H3V L;  3NUH A;  3S15 C;  2CFA A;  3TFH A;  4YG2 A;  4A3G K;  3AD7 C;  2JA7 K;  1VJE A;  3LAJ A;  3PIP S;  3GIR A;  3GTJ A;  4A3B C;  3GTL A;  4C2M C;  2ZJR S;  4KMU A;  3S17 C;  5IOS A;  3FKI K;  4M1X A;  3HKZ D;  3G4A A;  2R7Z C;  4ILD A;  3JST A;  3PO3 K;  1I3Q C;  1O26 A;  4XSZ A;  2P8T A;  1TWC C;  3BUE A;  5M3F K;  5JVO A;  4MEY A;  1L0W A;  4WJ3 M;  4BY7 C;  1IQ0 A;  2VUM C;  3GTM C;  2XCQ A;  5IOR A;  1TWF C;  3FHZ A;  2ZJQ S;  1B4B A;  2JA8 K;  5C4J K;  5C3E K;  4YFK A;  3V4G A;  2NVY A;  4G7Z A;  3HKZ L;  4IOC S;  3S2D C;  2JH3 A;  2YU9 K;  1R9T A;  2JA6 C;  3GTK C;  3HOZ C;  3LPX A;  1EH1 A;  3K7A K;  1IW7 A;  3M3Y K;  1WIH A;  1WCM K;  1F7V A;  3M4O K;  2PPB A;  1XXA A;  4AH6 A;  3HXA A;  5IP9 K;  2PA8 D;  2R92 K;  5FLM C;  4IO9 S;  1XZQ B;  4Q5S A;  3H0G K;  5IYD C;  2R7Z A;  3RZO K;  3QX3 A;  2R93 K;  1EFW A;  4A3I K;  4Y7N C;  2E2H A;  3GTQ C;  2BE5 A;  3TTG A;  4ZH4 A;  3GTO C;  1O2A A;  2Y0S L;  4QJV A;  1SFO K;  1Y1W A;  3I4M C;  3I4N K;  4WJ4 A;  2L5N A;  3GEI A;  1TWG K;  1XPP A;  3OEP A;  2VUM A;  1XZP B;  4BY1 K;  3GTP C;  3BP3 A;  2V6S A;  5TJ3 A;  3GTJ C;  3GTL C;  1K83 K;  5M5W K;  1PJ6 A;  5C44 K;  5DM6 S;  1PJ7 A;  3CQZ A;  1J6V A;  2JA6 A;  3S1Q C;  4GTF A;  5IYC K;  5CJ9 A;  2CFA B;  1FEU A;  1BGW A;  5D4D A;  4C3H K;  4C3I C;  4XLP A;  4A3M C;  1F93 A;  1EK8 A;  2EBB A;  3TFI A;  3H3V D;  5TMC A;  1EQR A;  4KAS A;  3HOU K;  4A3C C;  5C4X C;  4OIP A;  2GSN A;  1VGX A;  4GTD A;  1JQW A;  2GAG C;  1VRQ C;  5TMF A;  1TWH K;  4C45 A;  5IP7 K;  3S1M C;  3GTQ A;  4P9S A;  4A93 K;  3S16 K;  1C0A A;  4X6A K;  4GZY A;  3PO2 K;  4A3K C;  2ZUE A;  3T02 A;  1O2F B;  5C4X K;  4FM9 A;  4KN7 A;  1VH2 A;  1BJT A;  2NVX K;  3GTP A;  3HOY C;  4BBS C;  1ZBS A;  4KDD A;  2NVY K;  1DCP A;  4QIW D;  2RGR A;  4G0V A;  1I50 C;  4KAT A;  3SZZ A;  2GSU A;  2B63 C;  4BLA A;  2NVT C;  1R9T K;  4BBR K;  2A6E A;  2WAQ D;  1XXB A;  4LR2 A;  2E2H C;  1WOO A;  5IYB K;  4G7H A;  1IBA A;  4WCE S;  4A3D C;  4GTB A;  4KM9 A;  4DDQ A;  3AD8 C;  3S15 K;  1Y1W C;  1VLO A;  4A3E C;  1JVI A;  3Q3Q A;  4KB2 A;  1ISE A;  4A3B K;  4C2M K;  3A8J A;  1IE0 A;  4KMD A;  3S17 K;  2KQ1 A;  4QIW L;  2R7Z K;  2A69 A;  4XLN A;  4AYB D;  4BLB A;  4GTL A;  1ZXO A;  1I6H C;  3CQZ C;  3S2H C;  1TWC K;  2WAQ L;  2V6U A;  2E2J C;  4GT9 A;  1Y1V C;  3S1R C;  1DD5 A;  4U67 S;  2Y0S D;  3HOX C;  4BY7 K;  1SMY A;  2VUM K;  3GTM K;  3GTG C;  1TWF K;  2GAH C;  4MEX A;  3SZY A;  4YFX A;  3N0B A;  3T00 A;  4KM8 A;  2O5J A;  4WFN S;  5JVG S;  1I50 A;  3S1N C;  3S2D K;  4LJZ A;  4AYB L;  1G51 A;  2B63 A;  3ORE A;  1HI9 A;  2JA6 K;  4RMF A;  3A8K A;  3AQO A;  4OIR A;  3GTK K;  3HOZ K;  4Q4Z A;  1X31 C;  4OIO A;  4C3J C;  1TWA C;  2L3U A;  1O2B A;  3WOD A;  2RH6 A;  4GTC A;  1O29 A;  5FLM K;  4P5B A;  2ZFZ A;  4WFA S;  2PMZ D;  4XCH A;  1J98 A;  2XCO A;  4A3L C;  3AQP A;  4NOI A;  5IYD K;  4IOA S;  3CF5 S;  3TFJ A;  3HOW C;  2V6T A;  1YX2 A;  1UV7 A;  4Y7N K;  1WQH A;  3GTQ K;  1JOE A;  1WOR A;  3GTO K;  1Y1V A;  4OIQ A;  4O2D A;  1IS1 A;  4GFQ A;  3I4M K;  1WCM A;  4LLG A;  3DLL S;  4LOW A;  4MQ9 A;  3HOV C;  4PAA A;  3GTG A;  3GTP K;  2PMZ L;  2FQT A; 
#chains in the Genus database with same CATH homology
 4BBS C;  2E2I C;  2JA8 K;  5C4J K;  4A3J C;  3GTJ K;  3GTL K;  5C3E K;  2NVY K;  4YFK A;  4QIW D;  4XSX A;  4G7Z A;  1K83 C;  3RZD C;  3HKZ L;  3S1N K;  1I50 C;  5C44 C;  3S2D C;  2B63 C;  2YU9 K;  2NVT C;  1R9T K;  4BXX K;  4A3F C;  2A6E A;  4BBR K;  3S1Q K;  2JA6 C;  2WAQ D;  1HQM A;  5IYC C;  2JA5 C;  2E2H C;  3S14 C;  3GTK C;  3HOZ C;  4C3J K;  5IYB K;  4G7H A;  3K7A K;  1IW7 A;  1TWA K;  4C3I K;  1BDF A;  2NVQ C;  4A3D C;  4A3M K;  3M3Y K;  4C3H C;  1WCM K;  3S15 K;  3M4O K;  2PPB A;  1Y1W C;  5IP9 K;  4Y52 C;  1YNJ A;  4A3E C;  2PA8 L;  2E2I K;  2WB1 D;  2PA8 D;  2R92 K;  4A3C K;  5FLM C;  4A3G C;  4A3B K;  4C2M K;  4LK1 A;  2JA7 C;  4A3L K;  1ZYR A;  3S17 K;  4OIN A;  3HOU C;  4Q5S A;  4QIW L;  2R7Z K;  3DXJ A;  2A69 A;  3FKI C;  5IYD C;  3EQL A;  3HOY C;  4YFN A;  3H0G K;  4LK0 A;  4A3F K;  3HOW K;  3RZO K;  4XLN A;  4AYB D;  3S1M K;  2R93 K;  1I6H C;  1TWH C;  3CQZ C;  3S2H C;  1I6V A;  5IP7 C;  2CW0 A;  4Y7N C;  1TWC K;  2WAQ L;  3GTQ C;  1YNN A;  2BE5 A;  4A3I K;  2NVQ K;  4ZH4 A;  2E2J C;  1Y1V C;  3GTO C;  2Y0S L;  5M3M K;  4QJV A;  1SFO K;  3S1R C;  4A93 C;  3S16 C;  2Y0S D;  3HOX C;  3I4M C;  3I4N K;  3HOV K;  4A3K K;  4X6A C;  1SMY A;  2VUM K;  3GTM K;  4BY7 K;  4G7O A;  1TWG K;  1XPP A;  3GTG C;  1TWF K;  3PO2 C;  2WB1 L;  1I3Q K;  4BY1 K;  3HOY K;  3GTP C;  4BBS K;  4MEX A;  4A3J K;  4JK1 A;  2NVX C;  4YFX A;  2JA8 C;  5C4J C;  3RZD K;  3GTJ C;  3GTL C;  1K83 K;  5C3E C;  2NVY C;  5M5W K;  2O5J A;  1I50 K;  5C44 K;  3S2D K;  3S1N C;  2B63 K;  2A68 A;  4LJZ A;  4AYB L;  2NVT K;  2JA6 K;  2YU9 C;  1R9T C;  4QJV B;  5M5X K;  4BBR C;  2A6H A;  3S1Q C;  3PO3 C;  4OIR A;  5IYC K;  2E2H K;  2JA5 K;  3GTK K;  3HOZ K;  3S14 K;  4KN4 A;  4Q4Z A;  4A3D K;  4OIO A;  5FJ8 K;  5D4D A;  4C3H K;  4C3J C;  5IYB C;  3K7A C;  4C3I C;  1TWA C;  4XLP A;  4A3M C;  3M3Y C;  1Y1W K;  3H3V L;  4Y52 K;  1WCM C;  3S15 C;  3M4O C;  4A3E K;  3H3V D;  5IP9 C;  5TMC A;  3WOD A;  4YG2 A;  5FLM K;  4A3G K;  5M5Y K;  2JA7 K;  2PMZ D;  2R92 C;  3HOU K;  4A3C C;  5C4X C;  4A3B C;  4OIP A;  4C2M C;  4A3L C;  4KMU A;  3S17 C;  4NOI A;  3FKI K;  5IYD K;  3HKZ D;  2R7Z C;  3H0G C;  3HOW C;  3RZO C;  3PO3 K;  5TMF A;  1TWH K;  3CQZ K;  5IP7 K;  3S2H K;  1I6H K;  4Y7N K;  3S1M C;  3GTQ K;  4BXX C;  4XSZ A;  2R93 C;  2E2J K;  4A3I C;  1Y1V K;  3GTO K;  1TWC C;  2O5I A;  3S1R K;  4OIQ A;  3S16 K;  4A93 K;  3HOX K;  5M3F K;  3I4M K;  1SFO C;  4LLG A;  4MQ9 A;  4MEY A;  4X6A K;  3I4N C;  3HOV C;  4GZY A;  3GTG K;  3PO2 K;  4A3K C;  4BY7 C;  3GTP K;  2VUM C;  3GTM C;  5C4X K;  4KN7 A;  1TWG C;  2NVX K;  2PMZ L;  1TWF C;  1I3Q C;  4BY1 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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