4A3EC

Rna polymerase ii initial transcribing complex with a 5nt dna-rna hybrid and soaked with ampcpp
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
266
structure length
266
Chain Sequence
EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 63
structure length 266
sequence length 266
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
C PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4a3eC02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4a3eC01
3S15C 5FJ8K 5M3MK 5C44K 3S17K 3RZOC 1TWAK 3GTGK 2JA8C 2WB1D 4A3EK 1TWHK 3FKIK 4C3HK 1R9TC 5C4JC 4OIRA 3I4NC 2JA6K 3GTLK 3PO2K 2R93K 4BBRC 1WCMK 5IYDC 3HOWK 3S14K 5C4XC 3GTOK 2E2IK 3HOZK 3H3VD 3HKZL 3S1NK 3S1RK 5M5YK 1I3QK 3HOUK 5C44C 3S17C 1TWFK 3GTGC 4ZH4A 3S15K 4A3EC 4Q4ZA 2A68A 2PA8L 1TWHC 3FKIC 4C3HC 1TWCC 5D4DA 1Y1VK 3GTLC 3PO2C 2JA6C 2R93C 1I6HK 4OIQA 4LLGA 4A3IK 1WCMC 3S14C 3HOZC 3GTOC 2E2IC 4G7ZA 2Y0SL 3S1NC 4X6AK 3S1RC 3GTQK 1I3QC 3HOUC 3K7AK 5IYDK 5M3FK 1BDFA 1TWFC 4C2MC 3WODA 4XSZA 2O5JA 4LJZA 1XPPA 4AYBD 4QIWL 4YFKA 4Y7NK 1Y1VC 5TMFA 1I6HC 3HOVK 4A3LK 4OIOA 4A3IC 4GZYA 1TWCK 2PMZD 2NVYK 4KN4A 4BXXK 5IP7K 3GTPK 4X6AC 5IP9K 4KN7A 3GTQC 3K7AC 1I6VA 2E2HK 4XSXA 4A3JK 3RZDC 4A3CK 1SFOK 4G7HA 4JK1A 4QJVB 2A6EA 4MEYA 4A3FK 2YU9K 4C2MK 4YFXA 4Y7NC 4LK1A 2JA5K 1YNNA 3HOVC 4A3LC 2NVQC 2NVYC 2PPBA 4LK0A 5TMCA 4BXXC 4KMUA 5IP7C 4BY1C 3GTPC 1Y1WK 4A3KK 5IP9C 3GTMK 4Q5SA 3I4MK 2E2HC 4A3CC 2NVTK 4A3JC 1SFOC 2E2JK 4A3FC 4C3IK 3S1QK 3M3YK 2R92C 2YU9C 3RZDK 4BBSK 4QJVA 4A93K 3S1MK 3H0GK 2JA5C 5M5WK 5IYBK 3EQLA 1I50K 3HOXK 2WB1L 2NVXK 2A69A 1Y1WC 1K83K 4C3JK 4A3KC 3GTMC 2NVQK 3I4MC 3HKZD 2NVTC 5IYCK 4BY1K 4XLPA 4G7OA 3H3VL 2E2JC 4A3GK 3S1QC 4C3IC 3M3YC 4BBSC 4A93C 3S1MC 3H0GC 5IYBC 2PA8D 1I50C 5FLMC 3HOXC 2JA7K 2R92K 2WAQL 4OINA 4MEXA 2NVXC 4YG2A 1K83C 4C3JC 3DXJA 3GTKK 2Y0SD 5IYCC 4A3GC 4A3DK 4OIPA 4A3BK 3M4OK 1SMYA 4QIWD 2JA7C 3PO3K 4AYBL 4NOIA 3S2DC 2R7ZK 1TWGK 2BE5A 5FLMK 3CQZK 4MQ9A 2O5IA 4Y52K 1YNJA 2B63K 3GTKC 3GTJK 4A3MK 2PMZL 5C3EK 2VUMK 3S16K 3S2HK 5M5XK 4XLNA 4BY7K 4A3DC 1ZYRA 1TWAC 4YFNA 4A3BC 3M4OC 3HOYK 2WAQD 3PO3C 3RZOK 2A6HA 2CW0A 2R7ZC 1TWGC 3CQZC 2JA8K 1IW7A 4Y52C 3S2DK 2B63C 3GTJC 4A3MC 2VUMC 5C3EC 3HOWC 5C4JK 3S16C 3S2HC 1R9TK 3I4NK 4BY7C 4BBRK 5C4XK 1HQMA 3HOYC
chains in the Genus database with same CATH superfamily
5C44K 3GTGK 3SZZA 1IBAA 1TWHK 1R9TC 3PO2K 2JA6K 4KM9A 2R92A 4BBRC 5IYDC 3GTOK 4C45A 1I3QK 5M5YK 3HOUK 1VH2A 1O28A 4ZH4A 3AH5A 4Q4ZA 3T00A 5EGEA 3FKIC 4WF9S 1I6HK 2R93C 4OIQA 4LLGA 4A3IK 1WCMC 2PHCB 2E2IC 4G7ZA 2RH6A 3GTQK 1WSVA 4C2MC 1EK8A 4LJZA 1DCOA 1XPPA 4AYBD 4QIWL 2GSUA 5TMFA 4OIOA 2NVYK 4BXXK 4X6AC 3G4AA 4A3JK 1R9TA 4JK1A 2A6EA 4MEYA 1FEUA 2YU9K 4WJ4A 4LK1A 1YNNA 2ZFZA 1TWAA 2ZUFA 2EBBA 5TMCA 4KMUA 4BY1C 3ADAC 5IP9C 4Q5SA 3T01A 3I4MK 3FKIA 4LOWA 2R93A 4A3FC 1WCMA 3GEHA 4QJVA 2E2IA 1O2AA 4KAWX 5IOTA 4C3JK 4A3KC 1J98A 2D6FC 4GTAA 5IYCK 1EH1A 1O2FB 4G7OA 4GTBA 3H3VL 4A3GK 4C3IC 1WOOA 4KMHA 3A8JA 4BBSC 4A93C 1IL2A 3H0GC 1I50C 3HOXC 5EGHA 2R92K 4OINA 4GTFA 4GTCA 1VGXA 4GTEA 4P5BA 1F93A 1PJ5A 1WIHA 5DM7S 4A3DK 1TWCA 4OIPA 4QIWD 4NOIA 3S2DC 1EI6A 3PIOS 1O26A 3FHZA 1WOSA 5JVOA 2O5IA 2PMZL 5JVGS 3DLLS 5C3EK 3TFHA 4BY7K 4A3BC 3N0BA 3PO3C 2CW0A 2GAHC 3AQOA 4A3MC 3HOWC 1R9TK 3H0GA 1I50A 4G0UA 2P5MA 3LPXA 4BBRK 1HQMA 3HOYC 3S15C 2P8TA 5FJ8K 1TWAK 3AD8C 3GEIA 2JA8C 3OEPA 3HXAA 3FKIK 2XCOA 5C4JC 3I4NC 2R93K 1WCMK 4PABA 2E2IK 3H3VD 3HKZL 1PJ7A 4LQYA 4WFNS 4J3NA 5D4DA 3N0CA 3GTLC 3IPJA 3S14C 4X6AK 3S1NC 1HI9A 4IOCS 1VLOA 1TWFC 1VJEA 1IE0A 2V6SA 5M3FK 3TFIA 4YFKA 4FM9A 1J6WA 2ZJQS 1TWCK 2PMZD 1XXBA 1WQFA 2ZUEA 5IP9K 4KN7A 3RZDC 3FOEA 1YCLA 4G7HA 4QJVB 4A3FK 2L3UA 4A3LC 4PAAA 2L5NA 2PPBA 4LK0A 5IP7C 3GTPC 4A3KK 1XZQB 4A3CC 1AB4A 3GTLA 4C3IK 2KWAA 4BBSK 4A93K 1XZPB 3H0GK 2W7VA 1I50K 3HOXK 4KMDA 2WB1L 1TWFA 5IOSA 1UV7A 1Y1WC 1BJTA 1DCPA 2NVQK 3HKZD 2NVTC 2E2JC 3S1QC 1BGWA 3BUEA 3M3YC 5IYBC 5FLMC 4YG2A 1PJ6A 1ZXOA 3CF5S 4A3BK 3GTPA 2JA7C 3PO3K 2BE5A 4AH6A 4U67S 4A3MK 1EFWA 5M5XK 4XLNA 4LR2A 5E68A 1INNA 1O24A 3A8KA 1XXAA 1XZQA 3AD7C 1Y1WA 3HOYK 2WAQD 1ISEA 2A6HA 1G51A 1TWGC 2V6TA 1XZPA 2JA8K 1BS2A 2VUMC 1J6VA 1EQRA 5C4JK 3I4NK 2V6UA 4GTLA 5M3MK 1O2BA 2WB1D 3GTLK 3GSIA 3JSTA 2JA7A 3S14K 3S1NK 4G0WA 3S17C 2CFAA 1TWFK 3OREA 3V4GA 4A3EC 2JH3A 2A68A 4BLAA 4C3HC 3SZYA 3GEEA 1XXCA 3HOZC 3GIRA 4WCES 1TWGA 2Y0SL 1JOEA 3S1RC 5IYDK 2FQOA 4ILDA 5HL7S 2VUMA 3WODA 2O5JA 4GT9A 1Y1VC 4A3LK 3LAPA 4GZYA 2ZJRS 1DD5A 4KN4A 5IP7K 3GTPK 2KQ1A 3K7AC 4A3CK 4KM8A 4C2MK 4Y7NC 3HOVC 1Y1WK 3FOFA 2E2HC 4WILA 1X31C 2NVTK 1SFOC 2E2JK 3S1QK 4GTDA 2R92C 5CJ9A 3M3YK 2JA5C 5IYBK 3BP3A 3LAJA 3S0XA 3GTMC 4BY1K 1Y1VA 4KMAA 5JVHS 3S1MC 4M1XA 2JA7K 2WAQL 3GDZA 2NVXC 1ZQ1C 1K83C 1USOA 2Y0SD 2XCQA 1O25A 4P9SA 1YX2A 1O29A 2E2HA 1TWGK 1SFOA 4G0VA 3GTKC 2VUMK 2JA5A 4KATA 4RMFA 1ZYRA 1TWAC 4YFNA 3M4OC 3GTMA 3NUHA 3QX3A 2R7ZC 3CQZC 1RU0A 4Y52C 3S2DK 1C0AA 2B63C 3GTJC 3S16C 3S2HC 3AQPA 2KPUA 5CHPA 2NVXA 1K83A 2CFAB 3S17K 3RZOC 2Y3PA 1USMA 4KARA 4A3EK 4C3HK 4OIRA 4O2DA 4KB4A 3ERED 3HOWK 5C4XC 3HOZK 4IO9S 3S1RK 5C44C 3GTKA 3GTGC 3S15K 5JFEA 5HQHA 5IORA 1JQWA 2PA8L 1TWHC 3AD9C 1TWCC 1Y1VK 3PO2C 2JA6C 2R7ZA 3GTOC 1ZVUA 3LYWA 5IOQA 3CQZA 1WORA 1I3QC 3HOUC 3K7AK 2B63A 1BDFA 1WQGA 3GTJA 4XSZA 3Q3QA 1JVIA 2ZJPS 4KASA 4Y7NK 1I6HC 3HOVK 4A3IC 1O27A 2FQTA 5DM6S 4WFAS 3GTQC 2E2HK 1I6VA 4XSXA 5L46A 1SFOK 1B4BA 4KB2A 4YFXA 2JA5K 5TJ3A 3PIPS 2NVQC 2NVYC 4BXXC 3GTGA 4BKWA 3VA7A 3GTMK 1TWHA 5HL8A 4XCHA 4A3JC 2JA6A 2XCRB 2GAGC 4KDDA 4IOAS 1F7UA 3RZDK 2YU9C 3GTOA 3S1MK 5M5WK 3EQLA 1WOPA 2GSOA 4FZBA 1I3QA 1F9NA 3OPFA 1KQ4A 2A69A 1ZBSA 1K83K 3CAGA 3MMLB 2NVXK 1J6XA 3I4MC 4P5AA 4XLPA 1L0WA 1IS1A 2PA8D 3GTQA 1VRQC 4MEXA 4C3JC 3TTGA 4KC6A 3DXJA 3GTKK 5IYCC 4GFQA 3T02A 4A3GC 2NVYA 2RGRA 3M4OK 1SMYA 1WQHA 1IQ0A 1WSRA 3A8IA 4AYBL 2R7ZK 4WJ3M 4DDQA 1F7VA 5FLMK 3CQZK 4MQ9A 4WFBS 3L4JA 1YNJA 1DCHA 2GSNA 3GTJK 2YU9A 2B63K 4Y52K 3S16K 3S2HK 1GE9A 1B4AA 4A3DC 3G4CA 3N3YA 3RZOK 4BLBA 1IW7A 3L4KA 3TFJA 3BP8C 5C3EC 4BY7C 1V5VA 2KXYA 5C4XK
chains in the Genus database with same CATH topology
3S15C 5FJ8K 5M3MK 5C44K 3S17K 3RZOC 1TWAK 3GTGK 2JA8C 2WB1D 4A3EK 1TWHK 3FKIK 4C3HK 1R9TC 5C4JC 4OIRA 3I4NC 2JA6K 3GTLK 3PO2K 2R93K 4BBRC 1WCMK 5IYDC 3HOWK 3S14K 5C4XC 3GTOK 2E2IK 3HOZK 3H3VD 3HKZL 3S1NK 3S1RK 5M5YK 1I3QK 3HOUK 5C44C 3S17C 1TWFK 3GTGC 4ZH4A 3S15K 4A3EC 4Q4ZA 2A68A 2PA8L 1TWHC 3FKIC 4C3HC 1TWCC 5D4DA 1Y1VK 3GTLC 3PO2C 2JA6C 2R93C 1I6HK 4OIQA 4LLGA 4A3IK 1WCMC 3S14C 3HOZC 3GTOC 2E2IC 4G7ZA 2Y0SL 3S1NC 4X6AK 3S1RC 3GTQK 1I3QC 3HOUC 3K7AK 5IYDK 5M3FK 1BDFA 1TWFC 4C2MC 3WODA 4XSZA 2O5JA 4LJZA 1XPPA 4AYBD 4QIWL 4YFKA 4Y7NK 1Y1VC 5TMFA 1I6HC 3HOVK 4A3LK 4OIOA 4A3IC 4GZYA 1TWCK 2PMZD 2NVYK 4KN4A 4BXXK 5IP7K 3GTPK 4X6AC 5IP9K 4KN7A 3GTQC 3K7AC 1I6VA 2E2HK 4XSXA 4A3JK 3RZDC 4A3CK 1SFOK 4G7HA 4JK1A 4QJVB 2A6EA 4MEYA 4A3FK 2YU9K 4C2MK 4YFXA 4Y7NC 4LK1A 2JA5K 1YNNA 3HOVC 4A3LC 2NVQC 2NVYC 2PPBA 4LK0A 5TMCA 4BXXC 4KMUA 5IP7C 4BY1C 3GTPC 1Y1WK 4A3KK 5IP9C 3GTMK 4Q5SA 3I4MK 2E2HC 4A3CC 2NVTK 4A3JC 1SFOC 2E2JK 4A3FC 4C3IK 3S1QK 3M3YK 2R92C 2YU9C 3RZDK 4BBSK 4QJVA 4A93K 3S1MK 3H0GK 2JA5C 5M5WK 5IYBK 3EQLA 1I50K 3HOXK 2WB1L 2NVXK 2A69A 1Y1WC 1K83K 4C3JK 4A3KC 3GTMC 2NVQK 3I4MC 3HKZD 2NVTC 5IYCK 4BY1K 4XLPA 4G7OA 3H3VL 2E2JC 4A3GK 3S1QC 4C3IC 3M3YC 4BBSC 4A93C 3S1MC 3H0GC 5IYBC 2PA8D 1I50C 5FLMC 3HOXC 2JA7K 2R92K 2WAQL 4OINA 4MEXA 2NVXC 4YG2A 1K83C 4C3JC 3DXJA 3GTKK 2Y0SD 5IYCC 4A3GC 4A3DK 4OIPA 4A3BK 3M4OK 1SMYA 4QIWD 2JA7C 3PO3K 4AYBL 4NOIA 3S2DC 2R7ZK 1TWGK 2BE5A 5FLMK 3CQZK 4MQ9A 2O5IA 4Y52K 1YNJA 2B63K 3GTKC 3GTJK 4A3MK 2PMZL 5C3EK 2VUMK 3S16K 3S2HK 5M5XK 4XLNA 4BY7K 4A3DC 1ZYRA 1TWAC 4YFNA 4A3BC 3M4OC 3HOYK 2WAQD 3PO3C 3RZOK 2A6HA 2CW0A 2R7ZC 1TWGC 3CQZC 2JA8K 1IW7A 4Y52C 3S2DK 2B63C 3GTJC 4A3MC 2VUMC 5C3EC 3HOWC 5C4JK 3S16C 3S2HC 1R9TK 3I4NK 4BY7C 4BBRK 5C4XK 1HQMA 3HOYC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S15 C;  5FJ8 K;  5M3M K;  5C44 K;  3S17 K;  3RZO C;  1TWA K;  3GTG K;  2JA8 C;  2WB1 D;  4A3E K;  1TWH K;  3FKI K;  4C3H K;  1R9T C;  5C4J C;  4OIR A;  3I4N C;  2JA6 K;  3GTL K;  3PO2 K;  2R93 K;  4BBR C;  1WCM K;  5IYD C;  3HOW K;  3S14 K;  5C4X C;  3GTO K;  2E2I K;  3HOZ K;  3H3V D;  3HKZ L;  3S1N K;  3S1R K;  5M5Y K;  1I3Q K;  3HOU K;  5C44 C;  3S17 C;  1TWF K;  3GTG C;  4ZH4 A;  3S15 K;  4A3E C;  4Q4Z A;  2A68 A;  2PA8 L;  1TWH C;  3FKI C;  4C3H C;  1TWC C;  5D4D A;  1Y1V K;  3GTL C;  3PO2 C;  2JA6 C;  2R93 C;  1I6H K;  4OIQ A;  4LLG A;  4A3I K;  1WCM C;  3S14 C;  3HOZ C;  3GTO C;  2E2I C;  4G7Z A;  2Y0S L;  3S1N C;  4X6A K;  3S1R C;  3GTQ K;  1I3Q C;  3HOU C;  3K7A K;  5IYD K;  5M3F K;  1BDF A;  1TWF C;  4C2M C;  3WOD A;  4XSZ A;  2O5J A;  4LJZ A;  1XPP A;  4AYB D;  4QIW L;  4YFK A;  4Y7N K;  1Y1V C;  5TMF A;  1I6H C;  3HOV K;  4A3L K;  4OIO A;  4A3I C;  4GZY A;  1TWC K;  2PMZ D;  2NVY K;  4KN4 A;  4BXX K;  5IP7 K;  3GTP K;  4X6A C;  5IP9 K;  4KN7 A;  3GTQ C;  3K7A C;  1I6V A;  2E2H K;  4XSX A;  4A3J K;  3RZD C;  4A3C K;  1SFO K;  4G7H A;  4JK1 A;  4QJV B;  2A6E A;  4MEY A;  4A3F K;  2YU9 K;  4C2M K;  4YFX A;  4Y7N C;  4LK1 A;  2JA5 K;  1YNN A;  3HOV C;  4A3L C;  2NVQ C;  2NVY C;  2PPB A;  4LK0 A;  5TMC A;  4BXX C;  4KMU A;  5IP7 C;  4BY1 C;  3GTP C;  1Y1W K;  4A3K K;  5IP9 C;  3GTM K;  4Q5S A;  3I4M K;  2E2H C;  4A3C C;  2NVT K;  4A3J C;  1SFO C;  2E2J K;  4A3F C;  4C3I K;  3S1Q K;  3M3Y K;  2R92 C;  2YU9 C;  3RZD K;  4BBS K;  4QJV A;  4A93 K;  3S1M K;  3H0G K;  2JA5 C;  5M5W K;  5IYB K;  3EQL A;  1I50 K;  3HOX K;  2WB1 L;  2NVX K;  2A69 A;  1Y1W C;  1K83 K;  4C3J K;  4A3K C;  3GTM C;  2NVQ K;  3I4M C;  3HKZ D;  2NVT C;  5IYC K;  4BY1 K;  4XLP A;  4G7O A;  3H3V L;  2E2J C;  4A3G K;  3S1Q C;  4C3I C;  3M3Y C;  4BBS C;  4A93 C;  3S1M C;  3H0G C;  5IYB C;  2PA8 D;  1I50 C;  5FLM C;  3HOX C;  2JA7 K;  2R92 K;  2WAQ L;  4OIN A;  4MEX A;  2NVX C;  4YG2 A;  1K83 C;  4C3J C;  3DXJ A;  3GTK K;  2Y0S D;  5IYC C;  4A3G C;  4A3D K;  4OIP A;  4A3B K;  3M4O K;  1SMY A;  4QIW D;  2JA7 C;  3PO3 K;  4AYB L;  4NOI A;  3S2D C;  2R7Z K;  1TWG K;  2BE5 A;  5FLM K;  3CQZ K;  4MQ9 A;  2O5I A;  4Y52 K;  1YNJ A;  2B63 K;  3GTK C;  3GTJ K;  4A3M K;  2PMZ L;  5C3E K;  2VUM K;  3S16 K;  3S2H K;  5M5X K;  4XLN A;  4BY7 K;  4A3D C;  1ZYR A;  1TWA C;  4YFN A;  4A3B C;  3M4O C;  3HOY K;  2WAQ D;  3PO3 C;  3RZO K;  2A6H A;  2CW0 A;  2R7Z C;  1TWG C;  3CQZ C;  2JA8 K;  1IW7 A;  4Y52 C;  3S2D K;  2B63 C;  3GTJ C;  4A3M C;  2VUM C;  5C3E C;  3HOW C;  5C4J K;  3S16 C;  3S2H C;  1R9T K;  3I4N K;  4BY7 C;  4BBR K;  5C4X K;  1HQM A;  3HOY C; 
#chains in the Genus database with same CATH topology
 5C44 K;  3GTG K;  3SZZ A;  1IBA A;  1TWH K;  1R9T C;  3PO2 K;  2JA6 K;  4KM9 A;  2R92 A;  4BBR C;  5IYD C;  3GTO K;  4C45 A;  1I3Q K;  5M5Y K;  3HOU K;  1VH2 A;  1O28 A;  4ZH4 A;  3AH5 A;  4Q4Z A;  3T00 A;  5EGE A;  3FKI C;  4WF9 S;  1I6H K;  2R93 C;  4OIQ A;  4LLG A;  4A3I K;  1WCM C;  2PHC B;  2E2I C;  4G7Z A;  2RH6 A;  3GTQ K;  1WSV A;  4C2M C;  1EK8 A;  4LJZ A;  1DCO A;  1XPP A;  4AYB D;  4QIW L;  2GSU A;  5TMF A;  4OIO A;  2NVY K;  4BXX K;  4X6A C;  3G4A A;  4A3J K;  1R9T A;  4JK1 A;  2A6E A;  4MEY A;  1FEU A;  2YU9 K;  4WJ4 A;  4LK1 A;  1YNN A;  2ZFZ A;  1TWA A;  2ZUF A;  2EBB A;  5TMC A;  4KMU A;  4BY1 C;  3ADA C;  5IP9 C;  4Q5S A;  3T01 A;  3I4M K;  3FKI A;  4LOW A;  2R93 A;  4A3F C;  1WCM A;  3GEH A;  4QJV A;  2E2I A;  1O2A A;  4KAW X;  5IOT A;  4C3J K;  4A3K C;  1J98 A;  2D6F C;  4GTA A;  5IYC K;  1EH1 A;  1O2F B;  4G7O A;  4GTB A;  3H3V L;  4A3G K;  4C3I C;  1WOO A;  4KMH A;  3A8J A;  4BBS C;  4A93 C;  1IL2 A;  3H0G C;  1I50 C;  3HOX C;  5EGH A;  2R92 K;  4OIN A;  4GTF A;  4GTC A;  1VGX A;  4GTE A;  4P5B A;  1F93 A;  1PJ5 A;  1WIH A;  5DM7 S;  4A3D K;  1TWC A;  4OIP A;  4QIW D;  4NOI A;  3S2D C;  1EI6 A;  3PIO S;  1O26 A;  3FHZ A;  1WOS A;  5JVO A;  2O5I A;  2PMZ L;  5JVG S;  3DLL S;  5C3E K;  3TFH A;  4BY7 K;  4A3B C;  3N0B A;  3PO3 C;  2CW0 A;  2GAH C;  3AQO A;  4A3M C;  3HOW C;  1R9T K;  3H0G A;  1I50 A;  4G0U A;  2P5M A;  3LPX A;  4BBR K;  1HQM A;  3HOY C;  3S15 C;  2P8T A;  5FJ8 K;  1TWA K;  3AD8 C;  3GEI A;  2JA8 C;  3OEP A;  3HXA A;  3FKI K;  2XCO A;  5C4J C;  3I4N C;  2R93 K;  1WCM K;  4PAB A;  2E2I K;  3H3V D;  3HKZ L;  1PJ7 A;  4LQY A;  4WFN S;  4J3N A;  5D4D A;  3N0C A;  3GTL C;  3IPJ A;  3S14 C;  4X6A K;  3S1N C;  1HI9 A;  4IOC S;  1VLO A;  1TWF C;  1VJE A;  1IE0 A;  2V6S A;  5M3F K;  3TFI A;  4YFK A;  4FM9 A;  1J6W A;  2ZJQ S;  1TWC K;  2PMZ D;  1XXB A;  1WQF A;  2ZUE A;  5IP9 K;  4KN7 A;  3RZD C;  3FOE A;  1YCL A;  4G7H A;  4QJV B;  4A3F K;  2L3U A;  4A3L C;  4PAA A;  2L5N A;  2PPB A;  4LK0 A;  5IP7 C;  3GTP C;  4A3K K;  1XZQ B;  4A3C C;  1AB4 A;  3GTL A;  4C3I K;  2KWA A;  4BBS K;  4A93 K;  1XZP B;  3H0G K;  2W7V A;  1I50 K;  3HOX K;  4KMD A;  2WB1 L;  1TWF A;  5IOS A;  1UV7 A;  1Y1W C;  1BJT A;  1DCP A;  2NVQ K;  3HKZ D;  2NVT C;  2E2J C;  3S1Q C;  1BGW A;  3BUE A;  3M3Y C;  5IYB C;  5FLM C;  4YG2 A;  1PJ6 A;  1ZXO A;  3CF5 S;  4A3B K;  3GTP A;  2JA7 C;  3PO3 K;  2BE5 A;  4AH6 A;  4U67 S;  4A3M K;  1EFW A;  5M5X K;  4XLN A;  4LR2 A;  5E68 A;  1INN A;  1O24 A;  3A8K A;  1XXA A;  1XZQ A;  3AD7 C;  1Y1W A;  3HOY K;  2WAQ D;  1ISE A;  2A6H A;  1G51 A;  1TWG C;  2V6T A;  1XZP A;  2JA8 K;  1BS2 A;  2VUM C;  1J6V A;  1EQR A;  5C4J K;  3I4N K;  2V6U A;  4GTL A;  5M3M K;  1O2B A;  2WB1 D;  3GTL K;  3GSI A;  3JST A;  2JA7 A;  3S14 K;  3S1N K;  4G0W A;  3S17 C;  2CFA A;  1TWF K;  3ORE A;  3V4G A;  4A3E C;  2JH3 A;  2A68 A;  4BLA A;  4C3H C;  3SZY A;  3GEE A;  1XXC A;  3HOZ C;  3GIR A;  4WCE S;  1TWG A;  2Y0S L;  1JOE A;  3S1R C;  5IYD K;  2FQO A;  4ILD A;  5HL7 S;  2VUM A;  3WOD A;  2O5J A;  4GT9 A;  1Y1V C;  4A3L K;  3LAP A;  4GZY A;  2ZJR S;  1DD5 A;  4KN4 A;  5IP7 K;  3GTP K;  2KQ1 A;  3K7A C;  4A3C K;  4KM8 A;  4C2M K;  4Y7N C;  3HOV C;  1Y1W K;  3FOF A;  2E2H C;  4WIL A;  1X31 C;  2NVT K;  1SFO C;  2E2J K;  3S1Q K;  4GTD A;  2R92 C;  5CJ9 A;  3M3Y K;  2JA5 C;  5IYB K;  3BP3 A;  3LAJ A;  3S0X A;  3GTM C;  4BY1 K;  1Y1V A;  4KMA A;  5JVH S;  3S1M C;  4M1X A;  2JA7 K;  2WAQ L;  3GDZ A;  2NVX C;  1ZQ1 C;  1K83 C;  1USO A;  2Y0S D;  2XCQ A;  1O25 A;  4P9S A;  1YX2 A;  1O29 A;  2E2H A;  1TWG K;  1SFO A;  4G0V A;  3GTK C;  2VUM K;  2JA5 A;  4KAT A;  4RMF A;  1ZYR A;  1TWA C;  4YFN A;  3M4O C;  3GTM A;  3NUH A;  3QX3 A;  2R7Z C;  3CQZ C;  1RU0 A;  4Y52 C;  3S2D K;  1C0A A;  2B63 C;  3GTJ C;  3S16 C;  3S2H C;  3AQP A;  2KPU A;  5CHP A;  2NVX A;  1K83 A;  2CFA B;  3S17 K;  3RZO C;  2Y3P A;  1USM A;  4KAR A;  4A3E K;  4C3H K;  4OIR A;  4O2D A;  4KB4 A;  3ERE D;  3HOW K;  5C4X C;  3HOZ K;  4IO9 S;  3S1R K;  5C44 C;  3GTK A;  3GTG C;  3S15 K;  5JFE A;  5HQH A;  5IOR A;  1JQW A;  2PA8 L;  1TWH C;  3AD9 C;  1TWC C;  1Y1V K;  3PO2 C;  2JA6 C;  2R7Z A;  3GTO C;  1ZVU A;  3LYW A;  5IOQ A;  3CQZ A;  1WOR A;  1I3Q C;  3HOU C;  3K7A K;  2B63 A;  1BDF A;  1WQG A;  3GTJ A;  4XSZ A;  3Q3Q A;  1JVI A;  2ZJP S;  4KAS A;  4Y7N K;  1I6H C;  3HOV K;  4A3I C;  1O27 A;  2FQT A;  5DM6 S;  4WFA S;  3GTQ C;  2E2H K;  1I6V A;  4XSX A;  5L46 A;  1SFO K;  1B4B A;  4KB2 A;  4YFX A;  2JA5 K;  5TJ3 A;  3PIP S;  2NVQ C;  2NVY C;  4BXX C;  3GTG A;  4BKW A;  3VA7 A;  3GTM K;  1TWH A;  5HL8 A;  4XCH A;  4A3J C;  2JA6 A;  2XCR B;  2GAG C;  4KDD A;  4IOA S;  1F7U A;  3RZD K;  2YU9 C;  3GTO A;  3S1M K;  5M5W K;  3EQL A;  1WOP A;  2GSO A;  4FZB A;  1I3Q A;  1F9N A;  3OPF A;  1KQ4 A;  2A69 A;  1ZBS A;  1K83 K;  3CAG A;  3MML B;  2NVX K;  1J6X A;  3I4M C;  4P5A A;  4XLP A;  1L0W A;  1IS1 A;  2PA8 D;  3GTQ A;  1VRQ C;  4MEX A;  4C3J C;  3TTG A;  4KC6 A;  3DXJ A;  3GTK K;  5IYC C;  4GFQ A;  3T02 A;  4A3G C;  2NVY A;  2RGR A;  3M4O K;  1SMY A;  1WQH A;  1IQ0 A;  1WSR A;  3A8I A;  4AYB L;  2R7Z K;  4WJ3 M;  4DDQ A;  1F7V A;  5FLM K;  3CQZ K;  4MQ9 A;  4WFB S;  3L4J A;  1YNJ A;  1DCH A;  2GSN A;  3GTJ K;  2YU9 A;  2B63 K;  4Y52 K;  3S16 K;  3S2H K;  1GE9 A;  1B4A A;  4A3D C;  3G4C A;  3N3Y A;  3RZO K;  4BLB A;  1IW7 A;  3L4K A;  3TFJ A;  3BP8 C;  5C3E C;  4BY7 C;  1V5V A;  2KXY A;  5C4X K; 
#chains in the Genus database with same CATH homology
 3S15 C;  5FJ8 K;  5M3M K;  5C44 K;  3S17 K;  3RZO C;  1TWA K;  3GTG K;  2JA8 C;  2WB1 D;  4A3E K;  1TWH K;  3FKI K;  4C3H K;  1R9T C;  5C4J C;  4OIR A;  3I4N C;  2JA6 K;  3GTL K;  3PO2 K;  2R93 K;  4BBR C;  1WCM K;  5IYD C;  3HOW K;  3S14 K;  5C4X C;  3GTO K;  2E2I K;  3HOZ K;  3H3V D;  3HKZ L;  3S1N K;  3S1R K;  5M5Y K;  1I3Q K;  3HOU K;  5C44 C;  3S17 C;  1TWF K;  3GTG C;  4ZH4 A;  3S15 K;  4A3E C;  4Q4Z A;  2A68 A;  2PA8 L;  1TWH C;  3FKI C;  4C3H C;  1TWC C;  5D4D A;  1Y1V K;  3GTL C;  3PO2 C;  2JA6 C;  2R93 C;  1I6H K;  4OIQ A;  4LLG A;  4A3I K;  1WCM C;  3S14 C;  3HOZ C;  3GTO C;  2E2I C;  4G7Z A;  2Y0S L;  3S1N C;  4X6A K;  3S1R C;  3GTQ K;  1I3Q C;  3HOU C;  3K7A K;  5IYD K;  5M3F K;  1BDF A;  1TWF C;  4C2M C;  3WOD A;  4XSZ A;  2O5J A;  4LJZ A;  1XPP A;  4AYB D;  4QIW L;  4YFK A;  4Y7N K;  1Y1V C;  5TMF A;  1I6H C;  3HOV K;  4A3L K;  4OIO A;  4A3I C;  4GZY A;  1TWC K;  2PMZ D;  2NVY K;  4KN4 A;  4BXX K;  5IP7 K;  3GTP K;  4X6A C;  5IP9 K;  4KN7 A;  3GTQ C;  3K7A C;  1I6V A;  2E2H K;  4XSX A;  4A3J K;  3RZD C;  4A3C K;  1SFO K;  4G7H A;  4JK1 A;  4QJV B;  2A6E A;  4MEY A;  4A3F K;  2YU9 K;  4C2M K;  4YFX A;  4Y7N C;  4LK1 A;  2JA5 K;  1YNN A;  3HOV C;  4A3L C;  2NVQ C;  2NVY C;  2PPB A;  4LK0 A;  5TMC A;  4BXX C;  4KMU A;  5IP7 C;  4BY1 C;  3GTP C;  1Y1W K;  4A3K K;  5IP9 C;  3GTM K;  4Q5S A;  3I4M K;  2E2H C;  4A3C C;  2NVT K;  4A3J C;  1SFO C;  2E2J K;  4A3F C;  4C3I K;  3S1Q K;  3M3Y K;  2R92 C;  2YU9 C;  3RZD K;  4BBS K;  4QJV A;  4A93 K;  3S1M K;  3H0G K;  2JA5 C;  5M5W K;  5IYB K;  3EQL A;  1I50 K;  3HOX K;  2WB1 L;  2NVX K;  2A69 A;  1Y1W C;  1K83 K;  4C3J K;  4A3K C;  3GTM C;  2NVQ K;  3I4M C;  3HKZ D;  2NVT C;  5IYC K;  4BY1 K;  4XLP A;  4G7O A;  3H3V L;  2E2J C;  4A3G K;  3S1Q C;  4C3I C;  3M3Y C;  4BBS C;  4A93 C;  3S1M C;  3H0G C;  5IYB C;  2PA8 D;  1I50 C;  5FLM C;  3HOX C;  2JA7 K;  2R92 K;  2WAQ L;  4OIN A;  4MEX A;  2NVX C;  4YG2 A;  1K83 C;  4C3J C;  3DXJ A;  3GTK K;  2Y0S D;  5IYC C;  4A3G C;  4A3D K;  4OIP A;  4A3B K;  3M4O K;  1SMY A;  4QIW D;  2JA7 C;  3PO3 K;  4AYB L;  4NOI A;  3S2D C;  2R7Z K;  1TWG K;  2BE5 A;  5FLM K;  3CQZ K;  4MQ9 A;  2O5I A;  4Y52 K;  1YNJ A;  2B63 K;  3GTK C;  3GTJ K;  4A3M K;  2PMZ L;  5C3E K;  2VUM K;  3S16 K;  3S2H K;  5M5X K;  4XLN A;  4BY7 K;  4A3D C;  1ZYR A;  1TWA C;  4YFN A;  4A3B C;  3M4O C;  3HOY K;  2WAQ D;  3PO3 C;  3RZO K;  2A6H A;  2CW0 A;  2R7Z C;  1TWG C;  3CQZ C;  2JA8 K;  1IW7 A;  4Y52 C;  3S2D K;  2B63 C;  3GTJ C;  4A3M C;  2VUM C;  5C3E C;  3HOW C;  5C4J K;  3S16 C;  3S2H C;  1R9T K;  3I4N K;  4BY7 C;  4BBR K;  5C4X K;  1HQM A;  3HOY C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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