5D4DA

Crystal structure of thermus thermophilus product complex for transcription initiation with nad and ctp
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
229
structure length
229
Chain Sequence
SKLKAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPLRRILLSSIPGTAVTSVYIEDVLHEFSTIPGVKEDVVEIILNLKELVVRFLNPSLQTVTLLLKAEGPKEVKARDFLPVADVEIMNPDLHIATLEEGGRLNMEVRVDRGVGYVPAEKHGIKDRINAIPVDAVFSPVRRVAFQVEDTRLGQRTDLDKLTLRIWTDGSVTPLEALNQAVEILREHLTYFSNPQAAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Thermus thermophilus (strain hb27 / atcc baa-163 / dsm 7039)
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 52
structure length 229
sequence length 229
chains with identical sequence B, K, L
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
A PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
A PF03118 RNA_pol_A_CTD Bacterial RNA polymerase, alpha chain C terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 5d4dA02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 5d4dA01
4BXXK 4A3IK 4A3FK 2E2JK 3H0GK 5IYDC 4A3EC 5M3FK 4XLNA 1TWGC 1R9TK 4Y7NC 5C3EK 2NVXC 2O5IA 4G7HA 3GTMC 3HOZC 3K7AC 2JA6K 4A3BC 4C3IC 4YFKA 4A93C 4ZH4A 3S1QK 4G7ZA 1K83C 3HKZD 4A3MK 3S16K 1I6HK 4BY1C 4GZYA 1I3QC 4A3CC 2BE5A 4BXXC 3HKZL 4A3IC 5C4JK 4A3FC 2E2JC 4OIRA 2JA8K 1YNNA 3H0GC 2VUMK 3M3YK 2NVYK 2NVTK 4YFXA 5M5WK 2PA8D 4C3JK 1R9TC 1I3QK 5C3EC 3HOWK 1ZYRA 2JA6C 3GTOK 4OIQA 2B63C 2PA8L 2PPBA 3S1QC 4OIPA 4LJZA 1TWFK 4A3MC 4A3CK 3S16C 1HQMA 1I6HC 3S1RK 2A68A 4YFNA 3H3VD 4C3HK 5C4JC 2VUMC 2JA8C 3M3YC 1Y1VK 2NVYC 5FLMK 2NVTC 3H3VL 3CQZK 4OIOA 1BDFA 4C3JC 2JA5K 4LK0A 4LK1A 3M4OK 3DXJA 3HOWC 3FKIK 5M5XK 4LLGA 4NOIA 3GTOC 3GTGC 3S14K 3S1NK 2Y0SD 5TMCA 4X6AK 1TWAK 1Y1WK 2JA7K 4Y52K 1TWFC 4KMUA 3PO3K 5D4DA 4Q4ZA 4G7OA 1I50K 3S15K 4QIWD 2Y0SL 3S1RC 1YNJA 1TWHK 2E2HK 4OINA 4C3HC 5FJ8K 3HOYK 2R7ZK 3HOVK 5M5YK 3S1MK 4YG2A 4QIWL 1Y1VC 5IYCK 5FLMC 2R92K 1WCMK 3PO2K 3CQZC 4KN7A 4BY1K 2JA5C 3GTPK 5M3MK 3M4OC 2YU9K 3FKIC 4BY7K 1IW7A 3RZDK 3S14C 3S1NC 5C44K 4MEXA 3S2HK 4X6AC 1SFOK 3GTKK 2A6HA 1TWAC 1Y1WC 2JA7C 4A3GK 4Y52C 3WODA 3PO3C 1I50C 3S15C 4AYBD 3S2DK 4BBRK 4QJVB 5IYBK 4XSXA 1TWHC 2E2HC 2R7ZC 3HOYC 4A3KK 2R93K 3HOVC 3HOXK 2WAQD 3S1MC 4AYBL 5IYCC 5IP7K 4JK1A 4MEYA 2R92C 1WCMC 3PO2C 2E2IK 3I4NK 4QJVA 2PMZD 3GTPC 3I4MK 1XPPA 2NVQK 3S17K 2YU9C 4BY7C 2WAQL 3GTQK 3HOUK 5IP9K 4A3JK 3RZDC 3S2HC 1TWCK 5C44C 4A3DK 2PMZL 1SFOC 3GTKC 3RZOK 4A3GC 4A3LK 4C2MK 3S2DC 5TMFA 1SMYA 4BBRC 5IYBC 2O5JA 4A3KC 2R93C 5C4XK 3GTJK 4BBSK 4XLPA 3HOXC 2B63K 3GTLK 4XSZA 1I6VA 5IP7C 3I4NC 2E2IC 3EQLA 3I4MC 5IYDK 2NVQC 3S17C 4A3EK 2WB1D 3GTQC 3HOUC 5IP9C 4A3JC 1TWGK 4Q5SA 4Y7NK 4A3DC 1TWCC 2NVXK 4KN4A 3RZOC 3GTMK 3HOZK 4A3LC 2WB1L 2A6EA 3K7AK 4A3BK 4C2MC 4C3IK 2A69A 4A93K 2CW0A 1K83K 5C4XC 3GTJC 4BBSC 3GTGK 4MQ9A 3GTLC
chains in the Genus database with same CATH superfamily
5IOQA 1V5VA 4BKWA 5M3FK 4KM9A 1TWGC 3PIPS 2NVXC 4KMAA 3LAPA 5TJ3A 2O5IA 3GTMC 3DLLS 1F9NA 4A93C 1TWGA 3GIRA 3GTMA 4G0VA 4BXXC 5C4JK 4A3FC 2XCQA 4WCES 1YNNA 3T00A 1EQRA 3JSTA 2NVTK 4GT9A 1XZPB 3GTGA 2PA8D 5C3EC 1WQGA 2Y3PA 1ZYRA 2JA6C 1O2FB 4OIQA 3N0CA 2PA8L 4U67S 3GTOK 1XZPA 4LJZA 1TWFK 1XXAA 4LQYA 2EBBA 1HQMA 5EGEA 2JA6A 1Y1VA 1DD5A 3HXAA 2GSOA 3GEEA 5FLMK 2V6TA 3GEIA 4NOIA 1TWHA 5HQHA 1F7VA 4G7OA 4Q4ZA 1I50K 3S15K 4GTBA 2R92A 2E2HK 5FJ8K 3HOYK 5M5YK 3PO2K 3CQZC 4KN7A 3FOFA 2JA5C 4BY1K 1C0AA 3M4OC 4BY7K 1WOPA 3S1NC 2ZJQS 4MEXA 3GTKK 1Y1WC 4Y52C 4P9SA 1O25A 2GAGC 3SZZA 2RH6A 1EI6A 4KARA 3PIOS 3N3YA 5IORA 1WCMC 3I4NK 5JVHS 4AH6A 2YU9C 2V6UA 3GTQK 4A3JK 3RZDC 1WSRA 1TWCK 5C44C 1SFOC 1DCHA 4A3LK 3GSIA 3VA7A 3S2DC 5TMFA 5HL8A 1SFOA 5C4XK 3GTJK 4XLPA 4XSZA 5IP7C 4KDDA 4BLAA 2E2IC 1FEUA 1HI9A 3S17C 1KQ4A 3HOUC 1TWGK 2NVXK 2GAHC 3GTMK 4WJ4A 2A6EA 1USOA 2ZJPS 4A93K 3V4GA 1UV7A 1IQ0A 1PJ6A 3GTGK 4MQ9A 3GTLC 3FHZA 4BXXK 1R9TA 3GDZA 4A3FK 5IYDC 2KQ1A 4A3EC 4KMHA 1O24A 3GTLA 2ZUFA 5C3EK 3K7AC 2JA6K 5L46A 4YFKA 1K83C 1DCOA 1F93A 2NVYA 3T02A 1BS2A 4A3CC 2P8TA 2E2JC 3Q3QA 1O2BA 4KASA 2CFAB 2PPBA 1VJEA 4OIPA 3S16C 3S0XA 1I6HC 4FM9A 2CFAA 4YFNA 1XZQB 2L3UA 3CQZK 3AH5A 2JA5K 4LK0A 2ZUEA 4LK1A 1TWAA 5IOSA 2KXYA 3HOWC 3M4OK 1PJ7A 1XZQA 4LLGA 3GTGC 3S1NK 4G0UA 2FQOA 1Y1WK 3T01A 4Y52K 1IE0A 1YNJA 1B4AA 4KAWX 4C3HC 3GTPA 4YG2A 1Y1VC 1WCMK 5M3MK 2YU9K 1IW7A 1RU0A 3RZDK 5C44K 1SFOK 2JA7C 1VLOA 2R93A 3WODA 3S2DK 2D6FC 4QJVB 4GFQA 1TWHC 2R7ZC 2JA7A 3HOVC 3S1MC 1J6WA 5E68A 5IP7K 4JK1A 2R92C 2E2IK 4QJVA 4P5BA 2R7ZA 3S17K 3AQPA 4WJ3M 1USMA 3HOUK 4KM8A 1ZBSA 4A3GC 4KB2A 4GTFA 4BBRC 3LYWA 4A3KC 4IO9S 4WFBS 1VRQC 3A8KA 3HOXC 3GTLK 4RMFA 3QX3A 5IYDK 4A3EK 2WB1D 5IP9C 4Q5SA 3RZOC 3SZYA 3K7AK 2WB1L 1I3QA 2CW0A 1K83K 4IOAS 4LOWA 1WIHA 4BBSC 3TFHA 4BLBA 4A3CK 2E2JK 1AB4A 2B63A 1ISEA 4Y7NC 1X31C 3L4JA 4G7HA 2ZJRS 1XXCA 3HKZD 4ILDA 3S16K 2GSNA 1I6HK 1YX2A 3OPFA 3HKZL 4A3IC 3H0GC 4YFXA 3GTOA 1R9TC 4P5AA 3HOWK 1TWFA 3H0GA 3CF5S 3S1QC 3BP8C 1IL2A 4A3MC 1DCPA 4C45A 2A68A 4IOCS 4C3HK 2RGRA 2VUMC 2JA8C 3M3YC 2PHCB 1Y1VK 2NVYC 3TTGA 4C3JC 2VUMA 5M5XK 1ZXOA 1J6VA 1B4BA 5TMCA 2E2HA 2JA7K 3BP3A 3CAGA 4QIWD 4GTLA 3S1RC 1EFWA 1TWHK 2GSUA 4OINA 2L5NA 1G51A 2R7ZK 3HOVK 3S1MK 4QIWL 4FZBA 1JOEA 2R92K 3GTKA 3A8IA 3FKIC 1VGXA 1ZQ1C 3S14C 4X6AC 1BJTA 2A6HA 1TWAC 4A3GK 1O29A 3FKIA 3BUEA 3PO3C 4AYBD 4BBRK 4XSXA 4WILA 4DDQA 4A3KK 3HOXK 4GTDA 2WAQD 4AYBL 1JVIA 3GTQA 5IYCC 4KATA 4MEYA 1PJ5A 3GTPC 1XPPA 2WAQL 1WOOA 5IP9K 3S2HC 4GTAA 3RZOK 4GTEA 3LPXA 3GTJA 5IYBC 1SMYA 2W7VA 2R93C 4BBSK 3TFJA 2B63K 1WOSA 1O28A 2NVXA 3I4MC 2NVQC 2ZFZA 1EH1A 4Y7NK 4A3DC 1JQWA 1O2AA 4C2MC 5DM7S 1IS1A 4GTCA 4A3IK 3AQOA 3H0GK 3N0BA 4XLNA 1O27A 1R9TK 1WQHA 1J6XA 1WQFA 3HOZC 4LR2A 4A3BC 4C3IC 3ADAC 4ZH4A 3S1QK 4G7ZA 4A3MK 4O2DA 4BY1C 2V6SA 1F7UA 4GZYA 1I3QC 1ZVUA 2BE5A 2VUMK 4OIRA 2JA8K 1J98A 5DM6S 3M3YK 2NVYK 4KC6A 5JVOA 4WFNS 5M5WK 4C3JK 2B63C 4WFAS 1VH2A 1WORA 3NUHA 1IBAA 3FOEA 3S1RK 1WSVA 3H3VD 3CQZA 3GEHA 5C4JC 1BGWA 2JA5A 4KMDA 3MMLB 5IOTA 5CJ9A 2NVTC 4KB4A 3H3VL 4OIOA 1BDFA 1Y1WA 3DXJA 3AD9C 3FKIK 3GTOC 3S14K 3L4KA 2Y0SD 4X6AK 1TWAK 4PAAA 1L0WA 1TWFC 1EK8A 4KMUA 3PO3K 4G0WA 5CHPA 5D4DA 2Y0SL 3G4AA 1WCMA 2KPUA 4WF9S 5EGHA 2YU9A 3ERED 5IYCK 2JH3A 5FLMC 3GTPK 3S2HK 5HL7S 3OEPA 2XCOA 1I50C 3S15C 5IYBK 2E2IA 2E2HC 3AD8C 3HOYC 2R93K 5JFEA 5JVGS 1I50A 3PO2C 3TFIA 1GE9A 3AD7C 2PMZD 3A8JA 3I4MK 2NVQK 4BY7C 2P5MA 2XCRB 4A3DK 2PMZL 3GTKC 4C2MK 4XCHA 2O5JA 4M1XA 2KWAA 1I6VA 3I4NC 3EQLA 4PABA 2FQTA 3OREA 3G4CA 4J3NA 3GTQC 4A3JC 1TWCC 4KN4A 1K83A 1O26A 3HOZK 4A3LC 1XXBA 4A3BK 4C3IK 3LAJA 2A69A 1TWCA 1YCLA 1INNA 5C4XC 3GTJC 3IPJA 1I3QK
chains in the Genus database with same CATH topology
4BXXK 4A3IK 4A3FK 2E2JK 3H0GK 5IYDC 4A3EC 5M3FK 4XLNA 1TWGC 1R9TK 4Y7NC 5C3EK 2NVXC 2O5IA 4G7HA 3GTMC 3HOZC 3K7AC 2JA6K 4A3BC 4C3IC 4YFKA 4A93C 4ZH4A 3S1QK 4G7ZA 1K83C 3HKZD 4A3MK 3S16K 1I6HK 4BY1C 4GZYA 1I3QC 4A3CC 2BE5A 4BXXC 3HKZL 4A3IC 5C4JK 4A3FC 2E2JC 4OIRA 2JA8K 1YNNA 3H0GC 2VUMK 3M3YK 2NVYK 2NVTK 4YFXA 5M5WK 2PA8D 4C3JK 1R9TC 1I3QK 5C3EC 3HOWK 1ZYRA 2JA6C 3GTOK 4OIQA 2B63C 2PA8L 2PPBA 3S1QC 4OIPA 4LJZA 1TWFK 4A3MC 4A3CK 3S16C 1HQMA 1I6HC 3S1RK 2A68A 4YFNA 3H3VD 4C3HK 5C4JC 2VUMC 2JA8C 3M3YC 1Y1VK 2NVYC 5FLMK 2NVTC 3H3VL 3CQZK 4OIOA 1BDFA 4C3JC 2JA5K 4LK0A 4LK1A 3M4OK 3DXJA 3HOWC 3FKIK 5M5XK 4LLGA 4NOIA 3GTOC 3GTGC 3S14K 3S1NK 2Y0SD 5TMCA 4X6AK 1TWAK 1Y1WK 2JA7K 4Y52K 1TWFC 4KMUA 3PO3K 5D4DA 4Q4ZA 4G7OA 1I50K 3S15K 4QIWD 2Y0SL 3S1RC 1YNJA 1TWHK 2E2HK 4OINA 4C3HC 5FJ8K 3HOYK 2R7ZK 3HOVK 5M5YK 3S1MK 4YG2A 4QIWL 1Y1VC 5IYCK 5FLMC 2R92K 1WCMK 3PO2K 3CQZC 4KN7A 4BY1K 2JA5C 3GTPK 5M3MK 3M4OC 2YU9K 3FKIC 4BY7K 1IW7A 3RZDK 3S14C 3S1NC 5C44K 4MEXA 3S2HK 4X6AC 1SFOK 3GTKK 2A6HA 1TWAC 1Y1WC 2JA7C 4A3GK 4Y52C 3WODA 3PO3C 1I50C 3S15C 4AYBD 3S2DK 4BBRK 4QJVB 5IYBK 4XSXA 1TWHC 2E2HC 2R7ZC 3HOYC 4A3KK 2R93K 3HOVC 3HOXK 2WAQD 3S1MC 4AYBL 5IYCC 5IP7K 4JK1A 4MEYA 2R92C 1WCMC 3PO2C 2E2IK 3I4NK 4QJVA 2PMZD 3GTPC 3I4MK 1XPPA 2NVQK 3S17K 2YU9C 4BY7C 2WAQL 3GTQK 3HOUK 5IP9K 4A3JK 3RZDC 3S2HC 1TWCK 5C44C 4A3DK 2PMZL 1SFOC 3GTKC 3RZOK 4A3GC 4A3LK 4C2MK 3S2DC 5TMFA 1SMYA 4BBRC 5IYBC 2O5JA 4A3KC 2R93C 5C4XK 3GTJK 4BBSK 4XLPA 3HOXC 2B63K 3GTLK 4XSZA 1I6VA 5IP7C 3I4NC 2E2IC 3EQLA 3I4MC 5IYDK 2NVQC 3S17C 4A3EK 2WB1D 3GTQC 3HOUC 5IP9C 4A3JC 1TWGK 4Q5SA 4Y7NK 4A3DC 1TWCC 2NVXK 4KN4A 3RZOC 3GTMK 3HOZK 4A3LC 2WB1L 2A6EA 3K7AK 4A3BK 4C2MC 4C3IK 2A69A 4A93K 2CW0A 1K83K 5C4XC 3GTJC 4BBSC 3GTGK 4MQ9A 3GTLC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BXX K;  4A3I K;  4A3F K;  2E2J K;  3H0G K;  5IYD C;  4A3E C;  5M3F K;  4XLN A;  1TWG C;  1R9T K;  4Y7N C;  5C3E K;  2NVX C;  2O5I A;  4G7H A;  3GTM C;  3HOZ C;  3K7A C;  2JA6 K;  4A3B C;  4C3I C;  4YFK A;  4A93 C;  4ZH4 A;  3S1Q K;  4G7Z A;  1K83 C;  3HKZ D;  4A3M K;  3S16 K;  1I6H K;  4BY1 C;  4GZY A;  1I3Q C;  4A3C C;  2BE5 A;  4BXX C;  3HKZ L;  4A3I C;  5C4J K;  4A3F C;  2E2J C;  4OIR A;  2JA8 K;  1YNN A;  3H0G C;  2VUM K;  3M3Y K;  2NVY K;  2NVT K;  4YFX A;  5M5W K;  2PA8 D;  4C3J K;  1R9T C;  1I3Q K;  5C3E C;  3HOW K;  1ZYR A;  2JA6 C;  3GTO K;  4OIQ A;  2B63 C;  2PA8 L;  2PPB A;  3S1Q C;  4OIP A;  4LJZ A;  1TWF K;  4A3M C;  4A3C K;  3S16 C;  1HQM A;  1I6H C;  3S1R K;  2A68 A;  4YFN A;  3H3V D;  4C3H K;  5C4J C;  2VUM C;  2JA8 C;  3M3Y C;  1Y1V K;  2NVY C;  5FLM K;  2NVT C;  3H3V L;  3CQZ K;  4OIO A;  1BDF A;  4C3J C;  2JA5 K;  4LK0 A;  4LK1 A;  3M4O K;  3DXJ A;  3HOW C;  3FKI K;  5M5X K;  4LLG A;  4NOI A;  3GTO C;  3GTG C;  3S14 K;  3S1N K;  2Y0S D;  5TMC A;  4X6A K;  1TWA K;  1Y1W K;  2JA7 K;  4Y52 K;  1TWF C;  4KMU A;  3PO3 K;  5D4D A;  4Q4Z A;  4G7O A;  1I50 K;  3S15 K;  4QIW D;  2Y0S L;  3S1R C;  1YNJ A;  1TWH K;  2E2H K;  4OIN A;  4C3H C;  5FJ8 K;  3HOY K;  2R7Z K;  3HOV K;  5M5Y K;  3S1M K;  4YG2 A;  4QIW L;  1Y1V C;  5IYC K;  5FLM C;  2R92 K;  1WCM K;  3PO2 K;  3CQZ C;  4KN7 A;  4BY1 K;  2JA5 C;  3GTP K;  5M3M K;  3M4O C;  2YU9 K;  3FKI C;  4BY7 K;  1IW7 A;  3RZD K;  3S14 C;  3S1N C;  5C44 K;  4MEX A;  3S2H K;  4X6A C;  1SFO K;  3GTK K;  2A6H A;  1TWA C;  1Y1W C;  2JA7 C;  4A3G K;  4Y52 C;  3WOD A;  3PO3 C;  1I50 C;  3S15 C;  4AYB D;  3S2D K;  4BBR K;  4QJV B;  5IYB K;  4XSX A;  1TWH C;  2E2H C;  2R7Z C;  3HOY C;  4A3K K;  2R93 K;  3HOV C;  3HOX K;  2WAQ D;  3S1M C;  4AYB L;  5IYC C;  5IP7 K;  4JK1 A;  4MEY A;  2R92 C;  1WCM C;  3PO2 C;  2E2I K;  3I4N K;  4QJV A;  2PMZ D;  3GTP C;  3I4M K;  1XPP A;  2NVQ K;  3S17 K;  2YU9 C;  4BY7 C;  2WAQ L;  3GTQ K;  3HOU K;  5IP9 K;  4A3J K;  3RZD C;  3S2H C;  1TWC K;  5C44 C;  4A3D K;  2PMZ L;  1SFO C;  3GTK C;  3RZO K;  4A3G C;  4A3L K;  4C2M K;  3S2D C;  5TMF A;  1SMY A;  4BBR C;  5IYB C;  2O5J A;  4A3K C;  2R93 C;  5C4X K;  3GTJ K;  4BBS K;  4XLP A;  3HOX C;  2B63 K;  3GTL K;  4XSZ A;  1I6V A;  5IP7 C;  3I4N C;  2E2I C;  3EQL A;  3I4M C;  5IYD K;  2NVQ C;  3S17 C;  4A3E K;  2WB1 D;  3GTQ C;  3HOU C;  5IP9 C;  4A3J C;  1TWG K;  4Q5S A;  4Y7N K;  4A3D C;  1TWC C;  2NVX K;  4KN4 A;  3RZO C;  3GTM K;  3HOZ K;  4A3L C;  2WB1 L;  2A6E A;  3K7A K;  4A3B K;  4C2M C;  4C3I K;  2A69 A;  4A93 K;  2CW0 A;  1K83 K;  5C4X C;  3GTJ C;  4BBS C;  3GTG K;  4MQ9 A;  3GTL C; 
#chains in the Genus database with same CATH topology
 5IOQ A;  1V5V A;  4BKW A;  5M3F K;  4KM9 A;  1TWG C;  3PIP S;  2NVX C;  4KMA A;  3LAP A;  5TJ3 A;  2O5I A;  3GTM C;  3DLL S;  1F9N A;  4A93 C;  1TWG A;  3GIR A;  3GTM A;  4G0V A;  4BXX C;  5C4J K;  4A3F C;  2XCQ A;  4WCE S;  1YNN A;  3T00 A;  1EQR A;  3JST A;  2NVT K;  4GT9 A;  1XZP B;  3GTG A;  2PA8 D;  5C3E C;  1WQG A;  2Y3P A;  1ZYR A;  2JA6 C;  1O2F B;  4OIQ A;  3N0C A;  2PA8 L;  4U67 S;  3GTO K;  1XZP A;  4LJZ A;  1TWF K;  1XXA A;  4LQY A;  2EBB A;  1HQM A;  5EGE A;  2JA6 A;  1Y1V A;  1DD5 A;  3HXA A;  2GSO A;  3GEE A;  5FLM K;  2V6T A;  3GEI A;  4NOI A;  1TWH A;  5HQH A;  1F7V A;  4G7O A;  4Q4Z A;  1I50 K;  3S15 K;  4GTB A;  2R92 A;  2E2H K;  5FJ8 K;  3HOY K;  5M5Y K;  3PO2 K;  3CQZ C;  4KN7 A;  3FOF A;  2JA5 C;  4BY1 K;  1C0A A;  3M4O C;  4BY7 K;  1WOP A;  3S1N C;  2ZJQ S;  4MEX A;  3GTK K;  1Y1W C;  4Y52 C;  4P9S A;  1O25 A;  2GAG C;  3SZZ A;  2RH6 A;  1EI6 A;  4KAR A;  3PIO S;  3N3Y A;  5IOR A;  1WCM C;  3I4N K;  5JVH S;  4AH6 A;  2YU9 C;  2V6U A;  3GTQ K;  4A3J K;  3RZD C;  1WSR A;  1TWC K;  5C44 C;  1SFO C;  1DCH A;  4A3L K;  3GSI A;  3VA7 A;  3S2D C;  5TMF A;  5HL8 A;  1SFO A;  5C4X K;  3GTJ K;  4XLP A;  4XSZ A;  5IP7 C;  4KDD A;  4BLA A;  2E2I C;  1FEU A;  1HI9 A;  3S17 C;  1KQ4 A;  3HOU C;  1TWG K;  2NVX K;  2GAH C;  3GTM K;  4WJ4 A;  2A6E A;  1USO A;  2ZJP S;  4A93 K;  3V4G A;  1UV7 A;  1IQ0 A;  1PJ6 A;  3GTG K;  4MQ9 A;  3GTL C;  3FHZ A;  4BXX K;  1R9T A;  3GDZ A;  4A3F K;  5IYD C;  2KQ1 A;  4A3E C;  4KMH A;  1O24 A;  3GTL A;  2ZUF A;  5C3E K;  3K7A C;  2JA6 K;  5L46 A;  4YFK A;  1K83 C;  1DCO A;  1F93 A;  2NVY A;  3T02 A;  1BS2 A;  4A3C C;  2P8T A;  2E2J C;  3Q3Q A;  1O2B A;  4KAS A;  2CFA B;  2PPB A;  1VJE A;  4OIP A;  3S16 C;  3S0X A;  1I6H C;  4FM9 A;  2CFA A;  4YFN A;  1XZQ B;  2L3U A;  3CQZ K;  3AH5 A;  2JA5 K;  4LK0 A;  2ZUE A;  4LK1 A;  1TWA A;  5IOS A;  2KXY A;  3HOW C;  3M4O K;  1PJ7 A;  1XZQ A;  4LLG A;  3GTG C;  3S1N K;  4G0U A;  2FQO A;  1Y1W K;  3T01 A;  4Y52 K;  1IE0 A;  1YNJ A;  1B4A A;  4KAW X;  4C3H C;  3GTP A;  4YG2 A;  1Y1V C;  1WCM K;  5M3M K;  2YU9 K;  1IW7 A;  1RU0 A;  3RZD K;  5C44 K;  1SFO K;  2JA7 C;  1VLO A;  2R93 A;  3WOD A;  3S2D K;  2D6F C;  4QJV B;  4GFQ A;  1TWH C;  2R7Z C;  2JA7 A;  3HOV C;  3S1M C;  1J6W A;  5E68 A;  5IP7 K;  4JK1 A;  2R92 C;  2E2I K;  4QJV A;  4P5B A;  2R7Z A;  3S17 K;  3AQP A;  4WJ3 M;  1USM A;  3HOU K;  4KM8 A;  1ZBS A;  4A3G C;  4KB2 A;  4GTF A;  4BBR C;  3LYW A;  4A3K C;  4IO9 S;  4WFB S;  1VRQ C;  3A8K A;  3HOX C;  3GTL K;  4RMF A;  3QX3 A;  5IYD K;  4A3E K;  2WB1 D;  5IP9 C;  4Q5S A;  3RZO C;  3SZY A;  3K7A K;  2WB1 L;  1I3Q A;  2CW0 A;  1K83 K;  4IOA S;  4LOW A;  1WIH A;  4BBS C;  3TFH A;  4BLB A;  4A3C K;  2E2J K;  1AB4 A;  2B63 A;  1ISE A;  4Y7N C;  1X31 C;  3L4J A;  4G7H A;  2ZJR S;  1XXC A;  3HKZ D;  4ILD A;  3S16 K;  2GSN A;  1I6H K;  1YX2 A;  3OPF A;  3HKZ L;  4A3I C;  3H0G C;  4YFX A;  3GTO A;  1R9T C;  4P5A A;  3HOW K;  1TWF A;  3H0G A;  3CF5 S;  3S1Q C;  3BP8 C;  1IL2 A;  4A3M C;  1DCP A;  4C45 A;  2A68 A;  4IOC S;  4C3H K;  2RGR A;  2VUM C;  2JA8 C;  3M3Y C;  2PHC B;  1Y1V K;  2NVY C;  3TTG A;  4C3J C;  2VUM A;  5M5X K;  1ZXO A;  1J6V A;  1B4B A;  5TMC A;  2E2H A;  2JA7 K;  3BP3 A;  3CAG A;  4QIW D;  4GTL A;  3S1R C;  1EFW A;  1TWH K;  2GSU A;  4OIN A;  2L5N A;  1G51 A;  2R7Z K;  3HOV K;  3S1M K;  4QIW L;  4FZB A;  1JOE A;  2R92 K;  3GTK A;  3A8I A;  3FKI C;  1VGX A;  1ZQ1 C;  3S14 C;  4X6A C;  1BJT A;  2A6H A;  1TWA C;  4A3G K;  1O29 A;  3FKI A;  3BUE A;  3PO3 C;  4AYB D;  4BBR K;  4XSX A;  4WIL A;  4DDQ A;  4A3K K;  3HOX K;  4GTD A;  2WAQ D;  4AYB L;  1JVI A;  3GTQ A;  5IYC C;  4KAT A;  4MEY A;  1PJ5 A;  3GTP C;  1XPP A;  2WAQ L;  1WOO A;  5IP9 K;  3S2H C;  4GTA A;  3RZO K;  4GTE A;  3LPX A;  3GTJ A;  5IYB C;  1SMY A;  2W7V A;  2R93 C;  4BBS K;  3TFJ A;  2B63 K;  1WOS A;  1O28 A;  2NVX A;  3I4M C;  2NVQ C;  2ZFZ A;  1EH1 A;  4Y7N K;  4A3D C;  1JQW A;  1O2A A;  4C2M C;  5DM7 S;  1IS1 A;  4GTC A;  4A3I K;  3AQO A;  3H0G K;  3N0B A;  4XLN A;  1O27 A;  1R9T K;  1WQH A;  1J6X A;  1WQF A;  3HOZ C;  4LR2 A;  4A3B C;  4C3I C;  3ADA C;  4ZH4 A;  3S1Q K;  4G7Z A;  4A3M K;  4O2D A;  4BY1 C;  2V6S A;  1F7U A;  4GZY A;  1I3Q C;  1ZVU A;  2BE5 A;  2VUM K;  4OIR A;  2JA8 K;  1J98 A;  5DM6 S;  3M3Y K;  2NVY K;  4KC6 A;  5JVO A;  4WFN S;  5M5W K;  4C3J K;  2B63 C;  4WFA S;  1VH2 A;  1WOR A;  3NUH A;  1IBA A;  3FOE A;  3S1R K;  1WSV A;  3H3V D;  3CQZ A;  3GEH A;  5C4J C;  1BGW A;  2JA5 A;  4KMD A;  3MML B;  5IOT A;  5CJ9 A;  2NVT C;  4KB4 A;  3H3V L;  4OIO A;  1BDF A;  1Y1W A;  3DXJ A;  3AD9 C;  3FKI K;  3GTO C;  3S14 K;  3L4K A;  2Y0S D;  4X6A K;  1TWA K;  4PAA A;  1L0W A;  1TWF C;  1EK8 A;  4KMU A;  3PO3 K;  4G0W A;  5CHP A;  5D4D A;  2Y0S L;  3G4A A;  1WCM A;  2KPU A;  4WF9 S;  5EGH A;  2YU9 A;  3ERE D;  5IYC K;  2JH3 A;  5FLM C;  3GTP K;  3S2H K;  5HL7 S;  3OEP A;  2XCO A;  1I50 C;  3S15 C;  5IYB K;  2E2I A;  2E2H C;  3AD8 C;  3HOY C;  2R93 K;  5JFE A;  5JVG S;  1I50 A;  3PO2 C;  3TFI A;  1GE9 A;  3AD7 C;  2PMZ D;  3A8J A;  3I4M K;  2NVQ K;  4BY7 C;  2P5M A;  2XCR B;  4A3D K;  2PMZ L;  3GTK C;  4C2M K;  4XCH A;  2O5J A;  4M1X A;  2KWA A;  1I6V A;  3I4N C;  3EQL A;  4PAB A;  2FQT A;  3ORE A;  3G4C A;  4J3N A;  3GTQ C;  4A3J C;  1TWC C;  4KN4 A;  1K83 A;  1O26 A;  3HOZ K;  4A3L C;  1XXB A;  4A3B K;  4C3I K;  3LAJ A;  2A69 A;  1TWC A;  1YCL A;  1INN A;  5C4X C;  3GTJ C;  3IPJ A;  1I3Q K; 
#chains in the Genus database with same CATH homology
 4BXX K;  4A3I K;  4A3F K;  2E2J K;  3H0G K;  5IYD C;  4A3E C;  5M3F K;  4XLN A;  1TWG C;  1R9T K;  4Y7N C;  5C3E K;  2NVX C;  2O5I A;  4G7H A;  3GTM C;  3HOZ C;  3K7A C;  2JA6 K;  4A3B C;  4C3I C;  4YFK A;  4A93 C;  4ZH4 A;  3S1Q K;  4G7Z A;  1K83 C;  3HKZ D;  4A3M K;  3S16 K;  1I6H K;  4BY1 C;  4GZY A;  1I3Q C;  4A3C C;  2BE5 A;  4BXX C;  3HKZ L;  4A3I C;  5C4J K;  4A3F C;  2E2J C;  4OIR A;  2JA8 K;  1YNN A;  3H0G C;  2VUM K;  3M3Y K;  2NVY K;  2NVT K;  4YFX A;  5M5W K;  2PA8 D;  4C3J K;  1R9T C;  1I3Q K;  5C3E C;  3HOW K;  1ZYR A;  2JA6 C;  3GTO K;  4OIQ A;  2B63 C;  2PA8 L;  2PPB A;  3S1Q C;  4OIP A;  4LJZ A;  1TWF K;  4A3M C;  4A3C K;  3S16 C;  1HQM A;  1I6H C;  3S1R K;  2A68 A;  4YFN A;  3H3V D;  4C3H K;  5C4J C;  2VUM C;  2JA8 C;  3M3Y C;  1Y1V K;  2NVY C;  5FLM K;  2NVT C;  3H3V L;  3CQZ K;  4OIO A;  1BDF A;  4C3J C;  2JA5 K;  4LK0 A;  4LK1 A;  3M4O K;  3DXJ A;  3HOW C;  3FKI K;  5M5X K;  4LLG A;  4NOI A;  3GTO C;  3GTG C;  3S14 K;  3S1N K;  2Y0S D;  5TMC A;  4X6A K;  1TWA K;  1Y1W K;  2JA7 K;  4Y52 K;  1TWF C;  4KMU A;  3PO3 K;  5D4D A;  4Q4Z A;  4G7O A;  1I50 K;  3S15 K;  4QIW D;  2Y0S L;  3S1R C;  1YNJ A;  1TWH K;  2E2H K;  4OIN A;  4C3H C;  5FJ8 K;  3HOY K;  2R7Z K;  3HOV K;  5M5Y K;  3S1M K;  4YG2 A;  4QIW L;  1Y1V C;  5IYC K;  5FLM C;  2R92 K;  1WCM K;  3PO2 K;  3CQZ C;  4KN7 A;  4BY1 K;  2JA5 C;  3GTP K;  5M3M K;  3M4O C;  2YU9 K;  3FKI C;  4BY7 K;  1IW7 A;  3RZD K;  3S14 C;  3S1N C;  5C44 K;  4MEX A;  3S2H K;  4X6A C;  1SFO K;  3GTK K;  2A6H A;  1TWA C;  1Y1W C;  2JA7 C;  4A3G K;  4Y52 C;  3WOD A;  3PO3 C;  1I50 C;  3S15 C;  4AYB D;  3S2D K;  4BBR K;  4QJV B;  5IYB K;  4XSX A;  1TWH C;  2E2H C;  2R7Z C;  3HOY C;  4A3K K;  2R93 K;  3HOV C;  3HOX K;  2WAQ D;  3S1M C;  4AYB L;  5IYC C;  5IP7 K;  4JK1 A;  4MEY A;  2R92 C;  1WCM C;  3PO2 C;  2E2I K;  3I4N K;  4QJV A;  2PMZ D;  3GTP C;  3I4M K;  1XPP A;  2NVQ K;  3S17 K;  2YU9 C;  4BY7 C;  2WAQ L;  3GTQ K;  3HOU K;  5IP9 K;  4A3J K;  3RZD C;  3S2H C;  1TWC K;  5C44 C;  4A3D K;  2PMZ L;  1SFO C;  3GTK C;  3RZO K;  4A3G C;  4A3L K;  4C2M K;  3S2D C;  5TMF A;  1SMY A;  4BBR C;  5IYB C;  2O5J A;  4A3K C;  2R93 C;  5C4X K;  3GTJ K;  4BBS K;  4XLP A;  3HOX C;  2B63 K;  3GTL K;  4XSZ A;  1I6V A;  5IP7 C;  3I4N C;  2E2I C;  3EQL A;  3I4M C;  5IYD K;  2NVQ C;  3S17 C;  4A3E K;  2WB1 D;  3GTQ C;  3HOU C;  5IP9 C;  4A3J C;  1TWG K;  4Q5S A;  4Y7N K;  4A3D C;  1TWC C;  2NVX K;  4KN4 A;  3RZO C;  3GTM K;  3HOZ K;  4A3L C;  2WB1 L;  2A6E A;  3K7A K;  4A3B K;  4C2M C;  4C3I K;  2A69 A;  4A93 K;  2CW0 A;  1K83 K;  5C4X C;  3GTJ C;  4BBS C;  3GTG K;  4MQ9 A;  3GTL C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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