5IYDC

Human core-pic in the initial transcribing state (no iis)
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
275
structure length
275
Chain Sequence
MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna/rna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 56
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
C PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 5iydC02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 5iydC01
3PO2C 4OIRA 2A6HA 3GTPK 2R93K 3HOWK 3M4OK 4A3GC 1I6HC 4BBRK 4BY7K 3S1NC 4AYBD 2B63C 4QIWD 2E2HC 1TWGK 4YFNA 1SFOK 3S16K 1I6VA 2JA8C 1TWFC 4XLPA 3GTKC 3HOVC 1TWHC 2NVYC 3K7AK 3GTQC 3GTJK 3HOXK 4X6AK 2O5JA 3H3VD 2PMZD 3HOZK 3GTPC 4BBSC 1WCMK 4A3EC 3HOWC 3M4OC 2R93C 3H0GK 2NVXK 3GTOC 1K83C 2BE5A 3S1QC 5C3EK 3CQZK 4G7HA 1TWAC 4YFXA 5FJ8K 4A3DK 5IYCC 5M3FK 1SFOC 5IP9K 4YG2A 3S14C 3RZDK 3HOXC 2E2IK 3WODA 1Y1WC 3K7AC 2JA7C 2JA5K 3GTLK 4NOIA 5TMCA 1R9TC 3S1RK 5IYBC 3HOZC 4C3IK 5C44K 1WCMC 2JA6K 4KMUA 2WB1L 3CQZC 1HQMA 4A3KC 4A3DC 2A69A 3M3YK 3HOUC 5M5YK 4XSZA 2E2IC 3RZDC 2WAQL 4JK1A 2JA5C 3HKZD 4G7ZA 2A68A 2YU9C 2R7ZC 4QJVB 4A93K 4LK1A 4G7OA 2JA6C 4A3IK 5FLMK 5TMFA 4MQ9A 2VUMK 3PO3K 2E2JK 1BDFA 4QJVA 3M3YC 4C3HK 4BBRC 4BY7C 3DXJA 5M3MK 1TWGC 2A6EA 4MEYA 1Y1VK 4QIWL 4AYBL 3S16C 3S17K 3GTJC 4A93C 4X6AC 3S2HK 4LLGA 2CW0A 4Q4ZA 4Y7NK 2NVTK 4OIPA 1TWCK 4A3IC 5FLMC 2Y0SD 4A3MK 3PO3C 2E2JC 1ZYRA 2PMZL 3H0GC 3H3VL 5IYDK 3GTMK 2NVXC 3FKIK 3I4NK 3S1MK 4A3LK 5C3EC 4Y52K 5C4JK 4A3JK 4C3JK 4BY1K 2O5IA 4A3CK 4XSXA 3S15K 1I50K 5IP9C 3S17C 4XLNA 1I3QK 1SMYA 4C2MK 3RZOK 4BXXK 3GTLC 4A3FK 3S1RC 5C44C 3PO2K 4C3IC 4A3MC 3GTGK 2Y0SL 3I4NC 5C4XK 4A3GK 3S1MC 1I6HK 5C4JC 2B63K 2E2HK 3EQLA 3S2DK 4BY1C 4A3CC 2NVQK 3S15C 2JA8K 4C2MC 1I3QC 4BXXC 1TWFK 1TWHK 2NVYK 3HOVK 4A3FC 1YNNA 4A3BK 3HKZL 3HOYK 3I4MK 4BBSK 1IW7A 4A3EK 3GTGC 2PA8D 4GZYA 4OIOA 5C4XC 1K83K 5IP7K 2VUMC 3GTOK 1YNJA 3S1QK 1TWAK 3S2DC 5IYCK 4LK0A 4C3HC 4OINA 5M5WK 2NVQC 3S14K 1Y1VC 2JA7K 1Y1WK 4YFKA 4A3BC 1R9TK 3S2HC 3HOYC 4Y7NC 2PPBA 2NVTC 5IYBK 3I4MC 2R92K 1TWCC 2WB1D 4LJZA 5IP7C 2PA8L 5IYDC 4MEXA 4A3KK 5D4DA 3GTMC 3FKIC 4A3LC 4KN4A 4KN7A 3HOUK 4Y52C 3S1NK 2WAQD 4Q5SA 4A3JC 5M5XK 4ZH4A 4C3JC 1I50C 3RZOC 4OIQA 2YU9K 3GTKK 1XPPA 2R7ZK 2R92C 3GTQK
chains in the Genus database with same CATH superfamily
4KMAA 2R7ZA 4OIRA 1XXCA 3M4OK 4GTCA 4BBRK 3S1NC 4AYBD 2E2HC 2FQTA 4YFNA 1ZBSA 3GTKC 1TWHC 1J6WA 1TWGA 1EK8A 3HOWC 2NVXK 4FM9A 5C3EK 3CQZK 1TWAC 5IYCC 3A8JA 1SFOC 5EGEA 1Y1WC 3K7AC 3TFIA 5IOTA 4NOIA 5TMCA 5E68A 5IYBC 1FEUA 3CAGA 3HXAA 3TFHA 2A69A 3M3YK 1C0AA 3TTGA 4XSZA 1EFWA 3L4KA 3HKZD 2A68A 2YU9C 1WQHA 2W7VA 4G7OA 3LPXA 3BP8C 5M3MK 4BBRC 2KQ1A 3GSIA 3FOEA 2VUMA 2A6EA 4MEYA 4QIWL 1YX2A 5DM6S 2V6SA 4LLGA 2CW0A 4Q4ZA 3N3YA 4GTAA 3PO3C 2E2JC 2NVXC 1TWCA 3I4NK 5C3EC 4C3JK 4BY1K 2O5IA 4XSXA 3S15K 1I50K 4XLNA 1SMYA 2GSNA 4LR2A 4A3FK 3GTGK 3S1MC 4PABA 4BLAA 4C2MC 1I3QC 2B63A 2NVYK 1YNNA 4WJ4A 2L3UA 3HOYK 1DD5A 4BBSK 1IW7A 4A3EK 3GTQA 4IOAS 5IP7K 1K83K 5CJ9A 2R93A 4WJ3M 5M5WK 3GEEA 3GTOA 1EH1A 3LYWA 3OREA 2JA7K 3AD8C 4A3BC 1ZVUA 2WB1D 4LJZA 1R9TA 4A3KK 3AH5A 2EBBA 2PHCB 3S1NK 2WAQD 3BUEA 4C3JC 1O2BA 1XXBA 3GIRA 1I50C 4LOWA 3GTKK 2R7ZK 2R92C 4BLBA 2ZJPS 4P5BA 3MMLB 3FHZA 3HOWK 4KATA 2JA6A 4GTFA 4IOCS 1TWGK 3SZZA 1SFOK 1I6VA 4XLPA 3PIPS 4X6AK 2NVYC 4KMHA 3K7AK 3N0CA 2PMZD 1IE0A 3GTPC 4BBSC 3GEHA 4A3EC 1K83C 2BE5A 5HL7S 1DCPA 3JSTA 4KB4A 5IP9K 4YG2A 3HOXC 3WODA 2JA7C 2KXYA 4O2DA 4C3IK 1WCMC 3GTLA 4GTDA 2GAGC 4A3KC 3Q3QA 5M5YK 2E2IC 3RZDC 4JK1A 2JA5C 4G7ZA 2R7ZC 2GSUA 3N0BA 5TMFA 2VUMK 3PO3K 1BS2A 1BDFA 2E2JK 1JOEA 3G4AA 3DXJA 1TWGC 1WOSA 4ILDA 4X6AC 3AQPA 3LAPA 4Y7NK 1TWCK 2D6FC 3H3VL 3S1MK 1WOPA 4Y52K 1F9NA 1J98A 4KM9A 3FKIA 3A8IA 3T00A 3GEIA 5IP9C 1BJTA 1I3QK 4C2MK 2ZUFA 1VGXA 1X31C 3PO2K 4C3IC 1XXAA 3DLLS 2B63K 1F7UA 4FZBA 4J3NA 2JA8K 4BXXC 3HOVK 1VH2A 1J6VA 1HI9A 3TFJA 4A3BK 1TWFA 2PA8D 4LQYA 5C4XC 3GTOK 3S1QK 2VUMC 4M1XA 3L4JA 2NVQC 3A8KA 3T02A 4GTBA 1WIHA 1R9TK 4Y7NC 4G0VA 2R92K 3I4MC 1TWCC 1UV7A 1WORA 3AD7C 4AH6A 2ZJQS 4GTEA 1O2FB 2Y3PA 4KN4A 5CHPA 4Y52C 3CQZA 4DDQA 2KWAA 2KPUA 5IOSA 3PO2C 3GTPK 4PAAA 2B63C 1PJ5A 4QIWD 1VRQC 4KDDA 2JA8C 3HOXK 3HOVC 1EI6A 3GTQC 4BKWA 1YCLA 3GTJA 1PJ6A 1WCMK 2R93C 1WSRA 4KARA 3GTOC 3S1QC 4G7HA 2FQOA 3H0GA 1O29A 3BP3A 2E2IK 3RZDK 3GDZA 2V6UA 2JA5K 3GTLK 1DCHA 1R9TC 4P9SA 3HOZC 4KMUA 1IL2A 4A3DC 1O26A 1F93A 4KC6A 1USMA 2JA6C 2XCRB 1IBAA 4C45A 1WQGA 2GAHC 4U67S 3GTGA 4C3HK 4AYBL 4A93C 1RU0A 4RMFA 2NVTK 4OIPA 1O27A 1Y1VA 4A3IC 5FLMC 2Y0SD 2JH3A 1IQ0A 1KQ4A 5IYDK 1GE9A 3FKIK 4WILA 3GTMA 4GFQA 3S17C 4BXXK 3GTLC 3SZYA 1O25A 4WCES 4A3MC 1O24A 1JQWA 1B4AA 3G4CA 5C4XK 1BGWA 4KB2A 5IORA 2ZUEA 4A3GK 5C4JC 1I6HK 2P5MA 4A3CC 2RGRA 2NVQK 1TWFK 1PJ7A 2E2HA 3IPJA 3HKZL 3S0XA 3GTKA 3I4MK 1TWHA 5HL8A 4OIOA 1YNJA 1G51A 3S2DC 4LK0A 4C3HC 3S14K 1TWAA 1SFOA 2ZFZA 1V5VA 2NVTC 1Y1WA 2PA8L 5IYDC 4MEXA 2XCQA 3FKIC 5JVHS 4KN7A 3HOUK 4KMDA 5M5XK 4ZH4A 1F7VA 4OIQA 3GTQK 1EQRA 3AQOA 2YU9A 2A6HA 2R93K 4A3GC 1I6HC 4BY7K 4KASA 2ZJRS 3S16K 1ZXOA 1TWFC 3GTJK 1O28A 2O5JA 3H3VD 1VJEA 3HOZK 3H0GK 3M4OC 3OEPA 4GT9A 1WSVA 5FJ8K 4YFXA 4A3DK 5M3FK 4WFNS 2NVXA 5TJ3A 3S14C 3T01A 1VLOA 3NUHA 3S1RK 5C44K 2L5NA 1IS1A 2JA6K 1XZPB 2WB1L 3CQZC 1HQMA 3HOUC 2WAQL 4G0WA 1XZPA 5JVOA 4A93K 4QJVB 5DM7S 4KAWX 1I3QA 4LK1A 4A3IK 5FLMK 4MQ9A 1O2AA 4WFAS 5JFEA 4QJVA 3M3YC 2CFAB 4BY7C 1Y1VK 2RH6A 3S16C 3S17K 3GTJC 4P5AA 3S2HK 2CFAA 3ERED 1WOOA 4A3MK 1ZYRA 2PMZL 3H0GC 3GTMK 4A3LK 1DCOA 4WF9S 1WQFA 5IOQA 5C4JK 5L46A 5EGHA 4A3JK 1AB4A 4A3CK 5HQHA 3RZOK 4GTLA 1XZQB 3FOFA 1INNA 3AD9C 3S1RC 5C44C 3ADAC 1I50A 2R92A 2Y0SL 3QX3A 3I4NC 2P8TA 1XZQA 1USOA 2E2HK 3EQLA 3S2DK 4BY1C 3PIOS 3S15C 1ISEA 1TWHK 2XCOA 2GSOA 4A3FC 3CF5S 4G0UA 2NVYA 3VA7A 3GTGC 4GZYA 4XCHA 3LAJA 1JVIA 1TWAK 3GTPA 5IYCK 4OINA 4WFBS 5JVGS 1K83A 4IO9S 1Y1VC 1Y1WK 4YFKA 1ZQ1C 3S2HC 3HOYC 2PPBA 5IYBK 2JA7A 1B4BA 5IP7C 3OPFA 5D4DA 3GTMC 4A3LC 1WCMA 2V6TA 4KM8A 3V4GA 1J6XA 4Q5SA 4A3JC 1L0WA 3RZOC 2YU9K 1XPPA 2E2IA 2JA5A
chains in the Genus database with same CATH topology
3PO2C 4OIRA 2A6HA 3GTPK 2R93K 3HOWK 3M4OK 4A3GC 1I6HC 4BBRK 4BY7K 3S1NC 4AYBD 2B63C 4QIWD 2E2HC 1TWGK 4YFNA 1SFOK 3S16K 1I6VA 2JA8C 1TWFC 4XLPA 3GTKC 3HOVC 1TWHC 2NVYC 3K7AK 3GTQC 3GTJK 3HOXK 4X6AK 2O5JA 3H3VD 2PMZD 3HOZK 3GTPC 4BBSC 1WCMK 4A3EC 3HOWC 3M4OC 2R93C 3H0GK 2NVXK 3GTOC 1K83C 2BE5A 3S1QC 5C3EK 3CQZK 4G7HA 1TWAC 4YFXA 5FJ8K 4A3DK 5IYCC 5M3FK 1SFOC 5IP9K 4YG2A 3S14C 3RZDK 3HOXC 2E2IK 3WODA 1Y1WC 3K7AC 2JA7C 2JA5K 3GTLK 4NOIA 5TMCA 1R9TC 3S1RK 5IYBC 3HOZC 4C3IK 5C44K 1WCMC 2JA6K 4KMUA 2WB1L 3CQZC 1HQMA 4A3KC 4A3DC 2A69A 3M3YK 3HOUC 5M5YK 4XSZA 2E2IC 3RZDC 2WAQL 4JK1A 2JA5C 3HKZD 4G7ZA 2A68A 2YU9C 2R7ZC 4QJVB 4A93K 4LK1A 4G7OA 2JA6C 4A3IK 5FLMK 5TMFA 4MQ9A 2VUMK 3PO3K 2E2JK 1BDFA 4QJVA 3M3YC 4C3HK 4BBRC 4BY7C 3DXJA 5M3MK 1TWGC 2A6EA 4MEYA 1Y1VK 4QIWL 4AYBL 3S16C 3S17K 3GTJC 4A93C 4X6AC 3S2HK 4LLGA 2CW0A 4Q4ZA 4Y7NK 2NVTK 4OIPA 1TWCK 4A3IC 5FLMC 2Y0SD 4A3MK 3PO3C 2E2JC 1ZYRA 2PMZL 3H0GC 3H3VL 5IYDK 3GTMK 2NVXC 3FKIK 3I4NK 3S1MK 4A3LK 5C3EC 4Y52K 5C4JK 4A3JK 4C3JK 4BY1K 2O5IA 4A3CK 4XSXA 3S15K 1I50K 5IP9C 3S17C 4XLNA 1I3QK 1SMYA 4C2MK 3RZOK 4BXXK 3GTLC 4A3FK 3S1RC 5C44C 3PO2K 4C3IC 4A3MC 3GTGK 2Y0SL 3I4NC 5C4XK 4A3GK 3S1MC 1I6HK 5C4JC 2B63K 2E2HK 3EQLA 3S2DK 4BY1C 4A3CC 2NVQK 3S15C 2JA8K 4C2MC 1I3QC 4BXXC 1TWFK 1TWHK 2NVYK 3HOVK 4A3FC 1YNNA 4A3BK 3HKZL 3HOYK 3I4MK 4BBSK 1IW7A 4A3EK 3GTGC 2PA8D 4GZYA 4OIOA 5C4XC 1K83K 5IP7K 2VUMC 3GTOK 1YNJA 3S1QK 1TWAK 3S2DC 5IYCK 4LK0A 4C3HC 4OINA 5M5WK 2NVQC 3S14K 1Y1VC 2JA7K 1Y1WK 4YFKA 4A3BC 1R9TK 3S2HC 3HOYC 4Y7NC 2PPBA 2NVTC 5IYBK 3I4MC 2R92K 1TWCC 2WB1D 4LJZA 5IP7C 2PA8L 5IYDC 4MEXA 4A3KK 5D4DA 3GTMC 3FKIC 4A3LC 4KN4A 4KN7A 3HOUK 4Y52C 3S1NK 2WAQD 4Q5SA 4A3JC 5M5XK 4ZH4A 4C3JC 1I50C 3RZOC 4OIQA 2YU9K 3GTKK 1XPPA 2R7ZK 2R92C 3GTQK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PO2 C;  4OIR A;  2A6H A;  3GTP K;  2R93 K;  3HOW K;  3M4O K;  4A3G C;  1I6H C;  4BBR K;  4BY7 K;  3S1N C;  4AYB D;  2B63 C;  4QIW D;  2E2H C;  1TWG K;  4YFN A;  1SFO K;  3S16 K;  1I6V A;  2JA8 C;  1TWF C;  4XLP A;  3GTK C;  3HOV C;  1TWH C;  2NVY C;  3K7A K;  3GTQ C;  3GTJ K;  3HOX K;  4X6A K;  2O5J A;  3H3V D;  2PMZ D;  3HOZ K;  3GTP C;  4BBS C;  1WCM K;  4A3E C;  3HOW C;  3M4O C;  2R93 C;  3H0G K;  2NVX K;  3GTO C;  1K83 C;  2BE5 A;  3S1Q C;  5C3E K;  3CQZ K;  4G7H A;  1TWA C;  4YFX A;  5FJ8 K;  4A3D K;  5IYC C;  5M3F K;  1SFO C;  5IP9 K;  4YG2 A;  3S14 C;  3RZD K;  3HOX C;  2E2I K;  3WOD A;  1Y1W C;  3K7A C;  2JA7 C;  2JA5 K;  3GTL K;  4NOI A;  5TMC A;  1R9T C;  3S1R K;  5IYB C;  3HOZ C;  4C3I K;  5C44 K;  1WCM C;  2JA6 K;  4KMU A;  2WB1 L;  3CQZ C;  1HQM A;  4A3K C;  4A3D C;  2A69 A;  3M3Y K;  3HOU C;  5M5Y K;  4XSZ A;  2E2I C;  3RZD C;  2WAQ L;  4JK1 A;  2JA5 C;  3HKZ D;  4G7Z A;  2A68 A;  2YU9 C;  2R7Z C;  4QJV B;  4A93 K;  4LK1 A;  4G7O A;  2JA6 C;  4A3I K;  5FLM K;  5TMF A;  4MQ9 A;  2VUM K;  3PO3 K;  2E2J K;  1BDF A;  4QJV A;  3M3Y C;  4C3H K;  4BBR C;  4BY7 C;  3DXJ A;  5M3M K;  1TWG C;  2A6E A;  4MEY A;  1Y1V K;  4QIW L;  4AYB L;  3S16 C;  3S17 K;  3GTJ C;  4A93 C;  4X6A C;  3S2H K;  4LLG A;  2CW0 A;  4Q4Z A;  4Y7N K;  2NVT K;  4OIP A;  1TWC K;  4A3I C;  5FLM C;  2Y0S D;  4A3M K;  3PO3 C;  2E2J C;  1ZYR A;  2PMZ L;  3H0G C;  3H3V L;  5IYD K;  3GTM K;  2NVX C;  3FKI K;  3I4N K;  3S1M K;  4A3L K;  5C3E C;  4Y52 K;  5C4J K;  4A3J K;  4C3J K;  4BY1 K;  2O5I A;  4A3C K;  4XSX A;  3S15 K;  1I50 K;  5IP9 C;  3S17 C;  4XLN A;  1I3Q K;  1SMY A;  4C2M K;  3RZO K;  4BXX K;  3GTL C;  4A3F K;  3S1R C;  5C44 C;  3PO2 K;  4C3I C;  4A3M C;  3GTG K;  2Y0S L;  3I4N C;  5C4X K;  4A3G K;  3S1M C;  1I6H K;  5C4J C;  2B63 K;  2E2H K;  3EQL A;  3S2D K;  4BY1 C;  4A3C C;  2NVQ K;  3S15 C;  2JA8 K;  4C2M C;  1I3Q C;  4BXX C;  1TWF K;  1TWH K;  2NVY K;  3HOV K;  4A3F C;  1YNN A;  4A3B K;  3HKZ L;  3HOY K;  3I4M K;  4BBS K;  1IW7 A;  4A3E K;  3GTG C;  2PA8 D;  4GZY A;  4OIO A;  5C4X C;  1K83 K;  5IP7 K;  2VUM C;  3GTO K;  1YNJ A;  3S1Q K;  1TWA K;  3S2D C;  5IYC K;  4LK0 A;  4C3H C;  4OIN A;  5M5W K;  2NVQ C;  3S14 K;  1Y1V C;  2JA7 K;  1Y1W K;  4YFK A;  4A3B C;  1R9T K;  3S2H C;  3HOY C;  4Y7N C;  2PPB A;  2NVT C;  5IYB K;  3I4M C;  2R92 K;  1TWC C;  2WB1 D;  4LJZ A;  5IP7 C;  2PA8 L;  5IYD C;  4MEX A;  4A3K K;  5D4D A;  3GTM C;  3FKI C;  4A3L C;  4KN4 A;  4KN7 A;  3HOU K;  4Y52 C;  3S1N K;  2WAQ D;  4Q5S A;  4A3J C;  5M5X K;  4ZH4 A;  4C3J C;  1I50 C;  3RZO C;  4OIQ A;  2YU9 K;  3GTK K;  1XPP A;  2R7Z K;  2R92 C;  3GTQ K; 
#chains in the Genus database with same CATH topology
 4KMA A;  2R7Z A;  4OIR A;  1XXC A;  3M4O K;  4GTC A;  4BBR K;  3S1N C;  4AYB D;  2E2H C;  2FQT A;  4YFN A;  1ZBS A;  3GTK C;  1TWH C;  1J6W A;  1TWG A;  1EK8 A;  3HOW C;  2NVX K;  4FM9 A;  5C3E K;  3CQZ K;  1TWA C;  5IYC C;  3A8J A;  1SFO C;  5EGE A;  1Y1W C;  3K7A C;  3TFI A;  5IOT A;  4NOI A;  5TMC A;  5E68 A;  5IYB C;  1FEU A;  3CAG A;  3HXA A;  3TFH A;  2A69 A;  3M3Y K;  1C0A A;  3TTG A;  4XSZ A;  1EFW A;  3L4K A;  3HKZ D;  2A68 A;  2YU9 C;  1WQH A;  2W7V A;  4G7O A;  3LPX A;  3BP8 C;  5M3M K;  4BBR C;  2KQ1 A;  3GSI A;  3FOE A;  2VUM A;  2A6E A;  4MEY A;  4QIW L;  1YX2 A;  5DM6 S;  2V6S A;  4LLG A;  2CW0 A;  4Q4Z A;  3N3Y A;  4GTA A;  3PO3 C;  2E2J C;  2NVX C;  1TWC A;  3I4N K;  5C3E C;  4C3J K;  4BY1 K;  2O5I A;  4XSX A;  3S15 K;  1I50 K;  4XLN A;  1SMY A;  2GSN A;  4LR2 A;  4A3F K;  3GTG K;  3S1M C;  4PAB A;  4BLA A;  4C2M C;  1I3Q C;  2B63 A;  2NVY K;  1YNN A;  4WJ4 A;  2L3U A;  3HOY K;  1DD5 A;  4BBS K;  1IW7 A;  4A3E K;  3GTQ A;  4IOA S;  5IP7 K;  1K83 K;  5CJ9 A;  2R93 A;  4WJ3 M;  5M5W K;  3GEE A;  3GTO A;  1EH1 A;  3LYW A;  3ORE A;  2JA7 K;  3AD8 C;  4A3B C;  1ZVU A;  2WB1 D;  4LJZ A;  1R9T A;  4A3K K;  3AH5 A;  2EBB A;  2PHC B;  3S1N K;  2WAQ D;  3BUE A;  4C3J C;  1O2B A;  1XXB A;  3GIR A;  1I50 C;  4LOW A;  3GTK K;  2R7Z K;  2R92 C;  4BLB A;  2ZJP S;  4P5B A;  3MML B;  3FHZ A;  3HOW K;  4KAT A;  2JA6 A;  4GTF A;  4IOC S;  1TWG K;  3SZZ A;  1SFO K;  1I6V A;  4XLP A;  3PIP S;  4X6A K;  2NVY C;  4KMH A;  3K7A K;  3N0C A;  2PMZ D;  1IE0 A;  3GTP C;  4BBS C;  3GEH A;  4A3E C;  1K83 C;  2BE5 A;  5HL7 S;  1DCP A;  3JST A;  4KB4 A;  5IP9 K;  4YG2 A;  3HOX C;  3WOD A;  2JA7 C;  2KXY A;  4O2D A;  4C3I K;  1WCM C;  3GTL A;  4GTD A;  2GAG C;  4A3K C;  3Q3Q A;  5M5Y K;  2E2I C;  3RZD C;  4JK1 A;  2JA5 C;  4G7Z A;  2R7Z C;  2GSU A;  3N0B A;  5TMF A;  2VUM K;  3PO3 K;  1BS2 A;  1BDF A;  2E2J K;  1JOE A;  3G4A A;  3DXJ A;  1TWG C;  1WOS A;  4ILD A;  4X6A C;  3AQP A;  3LAP A;  4Y7N K;  1TWC K;  2D6F C;  3H3V L;  3S1M K;  1WOP A;  4Y52 K;  1F9N A;  1J98 A;  4KM9 A;  3FKI A;  3A8I A;  3T00 A;  3GEI A;  5IP9 C;  1BJT A;  1I3Q K;  4C2M K;  2ZUF A;  1VGX A;  1X31 C;  3PO2 K;  4C3I C;  1XXA A;  3DLL S;  2B63 K;  1F7U A;  4FZB A;  4J3N A;  2JA8 K;  4BXX C;  3HOV K;  1VH2 A;  1J6V A;  1HI9 A;  3TFJ A;  4A3B K;  1TWF A;  2PA8 D;  4LQY A;  5C4X C;  3GTO K;  3S1Q K;  2VUM C;  4M1X A;  3L4J A;  2NVQ C;  3A8K A;  3T02 A;  4GTB A;  1WIH A;  1R9T K;  4Y7N C;  4G0V A;  2R92 K;  3I4M C;  1TWC C;  1UV7 A;  1WOR A;  3AD7 C;  4AH6 A;  2ZJQ S;  4GTE A;  1O2F B;  2Y3P A;  4KN4 A;  5CHP A;  4Y52 C;  3CQZ A;  4DDQ A;  2KWA A;  2KPU A;  5IOS A;  3PO2 C;  3GTP K;  4PAA A;  2B63 C;  1PJ5 A;  4QIW D;  1VRQ C;  4KDD A;  2JA8 C;  3HOX K;  3HOV C;  1EI6 A;  3GTQ C;  4BKW A;  1YCL A;  3GTJ A;  1PJ6 A;  1WCM K;  2R93 C;  1WSR A;  4KAR A;  3GTO C;  3S1Q C;  4G7H A;  2FQO A;  3H0G A;  1O29 A;  3BP3 A;  2E2I K;  3RZD K;  3GDZ A;  2V6U A;  2JA5 K;  3GTL K;  1DCH A;  1R9T C;  4P9S A;  3HOZ C;  4KMU A;  1IL2 A;  4A3D C;  1O26 A;  1F93 A;  4KC6 A;  1USM A;  2JA6 C;  2XCR B;  1IBA A;  4C45 A;  1WQG A;  2GAH C;  4U67 S;  3GTG A;  4C3H K;  4AYB L;  4A93 C;  1RU0 A;  4RMF A;  2NVT K;  4OIP A;  1O27 A;  1Y1V A;  4A3I C;  5FLM C;  2Y0S D;  2JH3 A;  1IQ0 A;  1KQ4 A;  5IYD K;  1GE9 A;  3FKI K;  4WIL A;  3GTM A;  4GFQ A;  3S17 C;  4BXX K;  3GTL C;  3SZY A;  1O25 A;  4WCE S;  4A3M C;  1O24 A;  1JQW A;  1B4A A;  3G4C A;  5C4X K;  1BGW A;  4KB2 A;  5IOR A;  2ZUE A;  4A3G K;  5C4J C;  1I6H K;  2P5M A;  4A3C C;  2RGR A;  2NVQ K;  1TWF K;  1PJ7 A;  2E2H A;  3IPJ A;  3HKZ L;  3S0X A;  3GTK A;  3I4M K;  1TWH A;  5HL8 A;  4OIO A;  1YNJ A;  1G51 A;  3S2D C;  4LK0 A;  4C3H C;  3S14 K;  1TWA A;  1SFO A;  2ZFZ A;  1V5V A;  2NVT C;  1Y1W A;  2PA8 L;  5IYD C;  4MEX A;  2XCQ A;  3FKI C;  5JVH S;  4KN7 A;  3HOU K;  4KMD A;  5M5X K;  4ZH4 A;  1F7V A;  4OIQ A;  3GTQ K;  1EQR A;  3AQO A;  2YU9 A;  2A6H A;  2R93 K;  4A3G C;  1I6H C;  4BY7 K;  4KAS A;  2ZJR S;  3S16 K;  1ZXO A;  1TWF C;  3GTJ K;  1O28 A;  2O5J A;  3H3V D;  1VJE A;  3HOZ K;  3H0G K;  3M4O C;  3OEP A;  4GT9 A;  1WSV A;  5FJ8 K;  4YFX A;  4A3D K;  5M3F K;  4WFN S;  2NVX A;  5TJ3 A;  3S14 C;  3T01 A;  1VLO A;  3NUH A;  3S1R K;  5C44 K;  2L5N A;  1IS1 A;  2JA6 K;  1XZP B;  2WB1 L;  3CQZ C;  1HQM A;  3HOU C;  2WAQ L;  4G0W A;  1XZP A;  5JVO A;  4A93 K;  4QJV B;  5DM7 S;  4KAW X;  1I3Q A;  4LK1 A;  4A3I K;  5FLM K;  4MQ9 A;  1O2A A;  4WFA S;  5JFE A;  4QJV A;  3M3Y C;  2CFA B;  4BY7 C;  1Y1V K;  2RH6 A;  3S16 C;  3S17 K;  3GTJ C;  4P5A A;  3S2H K;  2CFA A;  3ERE D;  1WOO A;  4A3M K;  1ZYR A;  2PMZ L;  3H0G C;  3GTM K;  4A3L K;  1DCO A;  4WF9 S;  1WQF A;  5IOQ A;  5C4J K;  5L46 A;  5EGH A;  4A3J K;  1AB4 A;  4A3C K;  5HQH A;  3RZO K;  4GTL A;  1XZQ B;  3FOF A;  1INN A;  3AD9 C;  3S1R C;  5C44 C;  3ADA C;  1I50 A;  2R92 A;  2Y0S L;  3QX3 A;  3I4N C;  2P8T A;  1XZQ A;  1USO A;  2E2H K;  3EQL A;  3S2D K;  4BY1 C;  3PIO S;  3S15 C;  1ISE A;  1TWH K;  2XCO A;  2GSO A;  4A3F C;  3CF5 S;  4G0U A;  2NVY A;  3VA7 A;  3GTG C;  4GZY A;  4XCH A;  3LAJ A;  1JVI A;  1TWA K;  3GTP A;  5IYC K;  4OIN A;  4WFB S;  5JVG S;  1K83 A;  4IO9 S;  1Y1V C;  1Y1W K;  4YFK A;  1ZQ1 C;  3S2H C;  3HOY C;  2PPB A;  5IYB K;  2JA7 A;  1B4B A;  5IP7 C;  3OPF A;  5D4D A;  3GTM C;  4A3L C;  1WCM A;  2V6T A;  4KM8 A;  3V4G A;  1J6X A;  4Q5S A;  4A3J C;  1L0W A;  3RZO C;  2YU9 K;  1XPP A;  2E2I A;  2JA5 A; 
#chains in the Genus database with same CATH homology
 3PO2 C;  4OIR A;  2A6H A;  3GTP K;  2R93 K;  3HOW K;  3M4O K;  4A3G C;  1I6H C;  4BBR K;  4BY7 K;  3S1N C;  4AYB D;  2B63 C;  4QIW D;  2E2H C;  1TWG K;  4YFN A;  1SFO K;  3S16 K;  1I6V A;  2JA8 C;  1TWF C;  4XLP A;  3GTK C;  3HOV C;  1TWH C;  2NVY C;  3K7A K;  3GTQ C;  3GTJ K;  3HOX K;  4X6A K;  2O5J A;  3H3V D;  2PMZ D;  3HOZ K;  3GTP C;  4BBS C;  1WCM K;  4A3E C;  3HOW C;  3M4O C;  2R93 C;  3H0G K;  2NVX K;  3GTO C;  1K83 C;  2BE5 A;  3S1Q C;  5C3E K;  3CQZ K;  4G7H A;  1TWA C;  4YFX A;  5FJ8 K;  4A3D K;  5IYC C;  5M3F K;  1SFO C;  5IP9 K;  4YG2 A;  3S14 C;  3RZD K;  3HOX C;  2E2I K;  3WOD A;  1Y1W C;  3K7A C;  2JA7 C;  2JA5 K;  3GTL K;  4NOI A;  5TMC A;  1R9T C;  3S1R K;  5IYB C;  3HOZ C;  4C3I K;  5C44 K;  1WCM C;  2JA6 K;  4KMU A;  2WB1 L;  3CQZ C;  1HQM A;  4A3K C;  4A3D C;  2A69 A;  3M3Y K;  3HOU C;  5M5Y K;  4XSZ A;  2E2I C;  3RZD C;  2WAQ L;  4JK1 A;  2JA5 C;  3HKZ D;  4G7Z A;  2A68 A;  2YU9 C;  2R7Z C;  4QJV B;  4A93 K;  4LK1 A;  4G7O A;  2JA6 C;  4A3I K;  5FLM K;  5TMF A;  4MQ9 A;  2VUM K;  3PO3 K;  2E2J K;  1BDF A;  4QJV A;  3M3Y C;  4C3H K;  4BBR C;  4BY7 C;  3DXJ A;  5M3M K;  1TWG C;  2A6E A;  4MEY A;  1Y1V K;  4QIW L;  4AYB L;  3S16 C;  3S17 K;  3GTJ C;  4A93 C;  4X6A C;  3S2H K;  4LLG A;  2CW0 A;  4Q4Z A;  4Y7N K;  2NVT K;  4OIP A;  1TWC K;  4A3I C;  5FLM C;  2Y0S D;  4A3M K;  3PO3 C;  2E2J C;  1ZYR A;  2PMZ L;  3H0G C;  3H3V L;  5IYD K;  3GTM K;  2NVX C;  3FKI K;  3I4N K;  3S1M K;  4A3L K;  5C3E C;  4Y52 K;  5C4J K;  4A3J K;  4C3J K;  4BY1 K;  2O5I A;  4A3C K;  4XSX A;  3S15 K;  1I50 K;  5IP9 C;  3S17 C;  4XLN A;  1I3Q K;  1SMY A;  4C2M K;  3RZO K;  4BXX K;  3GTL C;  4A3F K;  3S1R C;  5C44 C;  3PO2 K;  4C3I C;  4A3M C;  3GTG K;  2Y0S L;  3I4N C;  5C4X K;  4A3G K;  3S1M C;  1I6H K;  5C4J C;  2B63 K;  2E2H K;  3EQL A;  3S2D K;  4BY1 C;  4A3C C;  2NVQ K;  3S15 C;  2JA8 K;  4C2M C;  1I3Q C;  4BXX C;  1TWF K;  1TWH K;  2NVY K;  3HOV K;  4A3F C;  1YNN A;  4A3B K;  3HKZ L;  3HOY K;  3I4M K;  4BBS K;  1IW7 A;  4A3E K;  3GTG C;  2PA8 D;  4GZY A;  4OIO A;  5C4X C;  1K83 K;  5IP7 K;  2VUM C;  3GTO K;  1YNJ A;  3S1Q K;  1TWA K;  3S2D C;  5IYC K;  4LK0 A;  4C3H C;  4OIN A;  5M5W K;  2NVQ C;  3S14 K;  1Y1V C;  2JA7 K;  1Y1W K;  4YFK A;  4A3B C;  1R9T K;  3S2H C;  3HOY C;  4Y7N C;  2PPB A;  2NVT C;  5IYB K;  3I4M C;  2R92 K;  1TWC C;  2WB1 D;  4LJZ A;  5IP7 C;  2PA8 L;  5IYD C;  4MEX A;  4A3K K;  5D4D A;  3GTM C;  3FKI C;  4A3L C;  4KN4 A;  4KN7 A;  3HOU K;  4Y52 C;  3S1N K;  2WAQ D;  4Q5S A;  4A3J C;  5M5X K;  4ZH4 A;  4C3J C;  1I50 C;  3RZO C;  4OIQ A;  2YU9 K;  3GTK K;  1XPP A;  2R7Z K;  2R92 C;  3GTQ K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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