2VJFA

Crystal structure of the mdm2-mdmx ring domain heterodimer
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
64
structure length
64
Chain Sequence
SSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the Mdm2/Mdmx Ring Domain Heterodimer Reveals Dimerization is Required for Their Ubiquitylation in Trans.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE MDM2
total genus 14
structure length 64
sequence length 64
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2007-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13920 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.10 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Zinc/RING finger domain, C3HC4 (zinc finger) 2vjfA00
2MD8C 5B8DA 2JMDA 3ZPV1 2EODA 4ZUXU 5B78A 1WEWA 3LQIA 2ECVA 3EB5A 4L58A 5TABA 2I50A 2MT5A 2KGGA 5KH7A 2YQLA 3O36A 1WGMA 4R8PK 5D1KB 1JM7A 5B75A 4B7YC 4YBMA 2YUCA 5LCWB 1IYMA 5TDWA 3ZNIA 1WENA 2JMIA 2ECTA 3PHDA 4QF2A 1WEMA 2L0BA 1WEQA 4MVTA 2EGPA 3N9QA 2KWJA 2YSMA 2KREA 3L11A 2K4DA 2MIQA 1FP0A 5C11A 2ECGA 4V3LC 4ZDTA 3M63A 3U5MA 5TBNA 3N9MA 4NN2A 1WESA 4AP4A 2LXPC 4L7XA 5DKAA 3MHSA 4A4BA 3LQHA 4QF3A 2G6QA 2KGIA 2YT5A 1G25A 3GL6A 4I7CA 1ZBDB 5B79A 5JG6A 5DINA 3O37A 3SHBA 2QJ0A 2CKLB 4MSXA 3I2DA 4TKPB 1LDKC 2ZETC 2E6SA 4N3WA 4LJNA 3FL2A 5FB0A 2KYUA 1HYIA 4FK5A 2H0DB 1X4UA 4BHWA 5FEYA 4LKAA 3M62A 4CA1A 2VJEB 2VP7A 4LLBA 3T6RA 4C9ZA 1T1HA 1MM3A 3C5KA 3KV5A 2ECNA 4BBQA 2MA5A 4O64A 3O7AA 2LRIC 4YBTA 2YYRA 4YBSA 2ECWA 2YW8A 1WEUA 2XB1A 2YQMA 1K2FA 2LGGA 3N9PA 2KU3A 4A4CA 2QIZA 2CKLA 2MUMA 1WFKA 4A49A 2JMJA 2YHNA 1F62A 2VNFA 2DX8A 1LDJB 4AUQB 2LGLA 4YABA 1HYJA 3KNVA 3O70A 3ZTGA 2YURA 4YADA 2F42A 2KIZA 2H0DA 4IC3A 2MNYA 2LGKA 2MD7B 2AN6A 2KR4A 2VJEA 2FUUA 3N9NA 2E6RA 2K17A 2L43A 5B76A 2K1JA 4GB0A 4LK9A 2RSDA 2XEUA 2BAYA 4PTBA 2C2LA 2YREA 4WZ0A 4N4FA 4FO9A 1VYXA 2C2VS 5J3XA 3LQJA 1RMDA 3EB6A 3SOUA 2PUYA 4R7EA 1XWHA 5G04B 5D1LB 4PPEA 4CCGX 3GV4A 4IC2A 3NG2A 2D8SA 2LV9A 2YHOA 1MM2A 4UI9B 3MHHA 5H1VA 3SOXA 2VJFB 3T7LA 4AYCB 4UP0A 3ASLA 2Y43A 2K16A 4GNFA 2VPDA 2MNZA 3KV6A 5LKXA 4LADB 1U6GB 5H9MA 1FBVA 3RPGB 5C13A 4A0CD 2CSZA 5G05B 4WZ2A 4Q6FA 1Z60A 4XI1A 2Y1MA 2RI7A 5TDRA 3ZPVE 2LXHC 3L1ZB 1WIMA 3IHPA 1WEVA 1WEEA 5FERA 2YSJA 2VJFA 2UZGA 4AYCA 3U5NA 3C6WA 5KH3A 3DPLR 2F6NA 3M99A 4FJCA 1WE9A 2ECJA 1VFYA 3U5PA 2L75A 3QZVA 1Z6UA 2M3HA 5AIUA 4V3KC 1CHCA 3RTRB 1X4IA 2LGVA 4YC9A 2KWNA 3U5OA 4GNEA 2Y1NA 5B77A 4YATA 2LN0A 2PNXA 5TRBA 2VPBA 4I7BA 2G45A 5KH9A 3ZVYA 4S3OB 1N87A 3RPGC 2KWKA 1JOCA 5FB1A 2HDPA 3HCSA 2MA6A 4GNDA 3O33A 4WA6A 2KE1A 1WEPA 3PURA 5H1UA 2FSAA 5EYAF 2JRJA 1VD4A 2L5UA 4I7DA 5I3LA 1E4UA 2KWOA 4ZQLA 4P5OB 2M6MA 2M85A 5H1TA 3PUQA 5LKTA 2FUIA 5D1MB 3ZVZB 3HCUA 5G0FA 2EA6A 2HYED 4WZ3B 2CT2A 3L1XA 3HCTA 2LQ6A 4R2YA 2YU4A 1V87A 4X3GA 1WILA 2F6JA 2VPGA 2M1RA 3VK6A 2G43A 3V43A 2ECIA 4B86C 2LDRA 3O35A 4YAXA 3ZYQA 2VPEA 4AVXA 3O34A 4FIPA 3KQIA 4S3OC 1Z2QA 2IDAA 4GNGA 5LKZA 1X4JA 4F52B 3N9OA 1JM7B 4W4UA 1WEOA 1DVPA 2QICA 1BORA 3DQVR 2CSYA 3HTKC 4UP5A 3N9LA 5AITA 5LKUA 2NAAA 2OXQC 2KFTA 3LRQA 2L80A 3SOWA
chains in the Genus database with same CATH superfamily
2MD8C 5B8DA 2JMDA 3ZPV1 2EODA 4ZUXU 2DJAA 5B78A 1WEWA 3LQIA 2ECVA 3EB5A 4L58A 5TABA 2I50A 2MT5A 2KGGA 5KH7A 2YQLA 2L7PA 3O36A 1WGMA 4R8PK 5D1KB 1JM7A 2CSVA 5B75A 2YVRA 4B7YC 4YBMA 2YUCA 5LCWB 4Z0OA 1IYMA 5TDWA 3ZNIA 4QQ4A 1WENA 2JMIA 2ECTA 3PHDA 5SVXA 4QF2A 1WEMA 2L0BA 1WEQA 4MVTA 2EGPA 3N9QA 2KWJA 2YSMA 2KREA 3L11A 2K4DA 2MIQA 1FP0A 5C11A 2ECGA 4V3LC 4ZDTA 3M63A 3U5MA 5TBNA 3N9MA 4NN2A 1WESA 4AP4A 2LXPC 2OWAA 5K3QA 4L7XA 5DKAA 3MHSA 1DCQA 4A4BA 3LQHA 3H7HA 4QF3A 2G6QA 3JUEA 2KGIA 2YT5A 5SVYA 1G25A 2XOZA 3GL6A 4I7CA 1ZBDB 5B79A 2FD4A 4H9DA 5JG6A 2B0OE 5DINA 3O37A 3Q1DA 4O62A 3SHBA 2QJ0A 2CKLB 2P57A 4MSXA 3I2DA 4TKPB 2E61A 1LDKC 2ZETC 2E6SA 4N3WA 4LJNA 3FL2A 5FB0A 2KYUA 1HYIA 4FK5A 2H0DB 1X4UA 4BHWA 3LVRE 5FEYA 5SVIB 4LKAA 3M62A 4CA1A 3FAOA 3MDBC 2VJEB 2VP7A 4LLBA 3T6RA 4C9ZA 1T1HA 1MM3A 2MKEA 3C5KA 3KV5A 3O47A 2ECNA 4BBQA 2KKXA 2MA5A 4O64A 3O7AA 2LRIC 4YBTA 2YYRA 4OGEA 4YBSA 2ECWA 2YW8A 1WEUA 2XB1A 2YQMA 1K2FA 2LGGA 3N9PA 2KU3A 4A4CA 2QIZA 2CKLA 2MUMA 1WFKA 4A49A 2JMJA 2CONA 2YHNA 1F62A 2VNFA 3FANA 2DX8A 1LDJB 3DDTA 4AUQB 2LGLA 4YABA 1HYJA 3KNVA 3O70A 3ZTGA 2YURA 4YADA 2F42A 2KIZA 2H0DA 4IC3A 2MNYA 2LGKA 2MD7B 2AN6A 2KR4A 2VJEA 2FUUA 3N9NA 2E6RA 2K17A 2L43A 5B76A 2K1JA 4GB0A 4LK9A 2RSDA 2XEUA 2BAYA 4PTBA 2C2LA 2YREA 4WZ0A 4N4FA 2D8UA 4FO9A 4Z0RA 1VYXA 2C2VS 5J3XA 3LQJA 1RMDA 3EB6A 3SOUA 3FJUB 2PUYA 4R7EA 1XWHA 5G04B 5D1LB 3FEHA 4PPEA 2LAUA 4CCGX 3GV4A 4IC2A 3NG2A 2D8SA 2LV9A 2YHOA 1MM2A 4UI9B 3MHHA 2DSMA 5H1VA 4F1PA 3SOXA 2VJFB 3T7LA 4AYCB 4UP0A 2CRRA 3M7KA 3ASLA 2Y43A 2FFWA 2K16A 4GNFA 2VPDA 2MNZA 3KV6A 5LKXA 4LADB 1U6GB 5H9MA 1FBVA 3RPGB 5C13A 4A0CD 2CSZA 5G05B 4WZ2A 3PLWA 4Q6FA 1Z60A 4XI1A 2Y1MA 2RI7A 5TDRA 3ZPVE 2LXHC 3L1ZB 1WIMA 3IHPA 4OGCA 1WEVA 1WEEA 5FERA 2YSJA 2VJFA 2UZGA 4AYCA 3U5NA 3C6WA 5KH3A 3DPLR 2JM3A 2F6NA 3E2DA 3M99A 4FJCA 1WE9A 2ECJA 1VFYA 3U5PA 2L75A 3QZVA 1Z6UA 2M3HA 5AIUA 4V3KC 1CHCA 5SVIA 3RTRB 1X4IA 2LGVA 4YC9A 2KWNA 3U5OA 4GNEA 2Y1NA 5B77A 4YATA 2LN0A 2PNXA 5TRBA 2VPBA 4I7BA 2CRWA 2G45A 5KH9A 3ZVYA 4S3OB 1N87A 3RPGC 2KWKA 1JOCA 5FB1A 2HDPA 3HCSA 2MA6A 2M13A 4GNDA 2JUNA 3O33A 4WA6A 2KE1A 1WEPA 3PURA 5H1UA 2FSAA 5EYAF 2JRJA 1VD4A 2L5UA 4I7DA 5I3LA 1E4UA 2KWOA 4ZQLA 4P5OB 3DWDA 2M6MA 2M85A 5H1TA 3PUQA 5LKTA 2FUIA 2XOYA 5D1MB 3ZVZB 3LVQE 3HCUA 5G0FA 2EA6A 2HYED 4WZ3B 2CT2A 3L1XA 3HCTA 2LQ6A 4R2YA 2YU4A 2XOCA 3LJUX 3KDEC 1V87A 4X3GA 1WILA 2F6JA 2VPGA 2M1RA 3VK6A 2G43A 3V43A 1MBMA 2ECIA 4B86C 2LDRA 3O35A 4YAXA 3ZYQA 2VPEA 4AVXA 3O34A 3T9KA 4FIPA 3KQIA 4S3OC 1Z2QA 2IDAA 3SUBA 4GNGA 5LKZA 1X4JA 4F52B 3N9OA 1JM7B 4W4UA 3LDYA 1WEOA 3FM8C 1DVPA 2EGMA 2QICA 1BORA 3DQVR 2CSYA 3HTKC 4UP5A 2IQJA 3N9LA 2RR4A 2XP0A 5AITA 5LKUA 2NAAA 2KKYA 2OXQC 2EXUA 2KFTA 3LRQA 2L80A 3SOWA
chains in the Genus database with same CATH topology
2MD8C 5B8DA 2JMDA 3ZPV1 2EODA 4ZUXU 5B78A 1WEWA 3LQIA 2ECVA 3EB5A 4L58A 5TABA 2I50A 2MT5A 2KGGA 5KH7A 2YQLA 3O36A 1WGMA 4R8PK 5D1KB 1JM7A 5B75A 4B7YC 4YBMA 2YUCA 5LCWB 1IYMA 5TDWA 3ZNIA 1WENA 2JMIA 2ECTA 3PHDA 4QF2A 1WEMA 2L0BA 1WEQA 4MVTA 2EGPA 3N9QA 2KWJA 2YSMA 2KREA 3L11A 2K4DA 2MIQA 1FP0A 5C11A 2ECGA 4V3LC 4ZDTA 3M63A 3U5MA 5TBNA 3N9MA 4NN2A 1WESA 4AP4A 2LXPC 4L7XA 5DKAA 3MHSA 4A4BA 3LQHA 4QF3A 2G6QA 2KGIA 2YT5A 1G25A 3GL6A 4I7CA 1ZBDB 5B79A 5JG6A 5DINA 3O37A 3SHBA 2QJ0A 2CKLB 4MSXA 3I2DA 4TKPB 1LDKC 2ZETC 2E6SA 4N3WA 4LJNA 3FL2A 5FB0A 2KYUA 1HYIA 4FK5A 2H0DB 1X4UA 4BHWA 5FEYA 4LKAA 3M62A 4CA1A 2VJEB 2VP7A 4LLBA 3T6RA 4C9ZA 1T1HA 1MM3A 3C5KA 3KV5A 2ECNA 4BBQA 2MA5A 4O64A 3O7AA 2LRIC 4YBTA 2YYRA 4YBSA 2ECWA 2YW8A 1WEUA 2XB1A 2YQMA 1K2FA 2LGGA 3N9PA 2KU3A 4A4CA 2QIZA 2CKLA 2MUMA 1WFKA 4A49A 2JMJA 2YHNA 1F62A 2VNFA 2DX8A 1LDJB 4AUQB 2LGLA 4YABA 1HYJA 3KNVA 3O70A 3ZTGA 2YURA 4YADA 2F42A 2KIZA 2H0DA 4IC3A 2MNYA 2LGKA 2MD7B 2AN6A 2KR4A 2VJEA 2FUUA 3N9NA 2E6RA 2K17A 2L43A 5B76A 2K1JA 4GB0A 4LK9A 2RSDA 2XEUA 2BAYA 4PTBA 2C2LA 2YREA 4WZ0A 4N4FA 4FO9A 1VYXA 2C2VS 5J3XA 3LQJA 1RMDA 3EB6A 3SOUA 2PUYA 4R7EA 1XWHA 5G04B 5D1LB 4PPEA 4CCGX 3GV4A 4IC2A 3NG2A 2D8SA 2LV9A 2YHOA 1MM2A 4UI9B 3MHHA 5H1VA 3SOXA 2VJFB 3T7LA 4AYCB 4UP0A 3ASLA 2Y43A 2K16A 4GNFA 2VPDA 2MNZA 3KV6A 5LKXA 4LADB 1U6GB 5H9MA 1FBVA 3RPGB 5C13A 4A0CD 2CSZA 5G05B 4WZ2A 4Q6FA 1Z60A 4XI1A 2Y1MA 2RI7A 5TDRA 3ZPVE 2LXHC 3L1ZB 1WIMA 3IHPA 1WEVA 1WEEA 5FERA 2YSJA 2VJFA 2UZGA 4AYCA 3U5NA 3C6WA 5KH3A 3DPLR 2F6NA 3M99A 4FJCA 1WE9A 2ECJA 1VFYA 3U5PA 2L75A 3QZVA 1Z6UA 2M3HA 5AIUA 4V3KC 1CHCA 3RTRB 1X4IA 2LGVA 4YC9A 2KWNA 3U5OA 4GNEA 2Y1NA 5B77A 4YATA 2LN0A 2PNXA 5TRBA 2VPBA 4I7BA 2G45A 5KH9A 3ZVYA 4S3OB 1N87A 3RPGC 2KWKA 1JOCA 5FB1A 2HDPA 3HCSA 2MA6A 4GNDA 3O33A 4WA6A 2KE1A 1WEPA 3PURA 5H1UA 2FSAA 5EYAF 2JRJA 1VD4A 2L5UA 4I7DA 5I3LA 1E4UA 2KWOA 4ZQLA 4P5OB 2M6MA 2M85A 5H1TA 3PUQA 5LKTA 2FUIA 5D1MB 3ZVZB 3HCUA 5G0FA 2EA6A 2HYED 4WZ3B 2CT2A 3L1XA 3HCTA 2LQ6A 4R2YA 2YU4A 1V87A 4X3GA 1WILA 2F6JA 2VPGA 2M1RA 3VK6A 2G43A 3V43A 2ECIA 4B86C 2LDRA 3O35A 4YAXA 3ZYQA 2VPEA 4AVXA 3O34A 4FIPA 3KQIA 4S3OC 1Z2QA 2IDAA 4GNGA 5LKZA 1X4JA 4F52B 3N9OA 1JM7B 4W4UA 1WEOA 1DVPA 2QICA 1BORA 3DQVR 2CSYA 3HTKC 4UP5A 3N9LA 5AITA 5LKUA 2NAAA 2OXQC 2KFTA 3LRQA 2L80A 3SOWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MD8 C;  5B8D A;  2JMD A;  3ZPV 1;  2EOD A;  4ZUX U;  5B78 A;  1WEW A;  3LQI A;  2ECV A;  3EB5 A;  4L58 A;  5TAB A;  2I50 A;  2MT5 A;  2KGG A;  5KH7 A;  2YQL A;  3O36 A;  1WGM A;  4R8P K;  5D1K B;  1JM7 A;  5B75 A;  4B7Y C;  4YBM A;  2YUC A;  5LCW B;  1IYM A;  5TDW A;  3ZNI A;  1WEN A;  2JMI A;  2ECT A;  3PHD A;  4QF2 A;  1WEM A;  2L0B A;  1WEQ A;  4MVT A;  2EGP A;  3N9Q A;  2KWJ A;  2YSM A;  2KRE A;  3L11 A;  2K4D A;  2MIQ A;  1FP0 A;  5C11 A;  2ECG A;  4V3L C;  4ZDT A;  3M63 A;  3U5M A;  5TBN A;  3N9M A;  4NN2 A;  1WES A;  4AP4 A;  2LXP C;  4L7X A;  5DKA A;  3MHS A;  4A4B A;  3LQH A;  4QF3 A;  2G6Q A;  2KGI A;  2YT5 A;  1G25 A;  3GL6 A;  4I7C A;  1ZBD B;  5B79 A;  5JG6 A;  5DIN A;  3O37 A;  3SHB A;  2QJ0 A;  2CKL B;  4MSX A;  3I2D A;  4TKP B;  1LDK C;  2ZET C;  2E6S A;  4N3W A;  4LJN A;  3FL2 A;  5FB0 A;  2KYU A;  1HYI A;  4FK5 A;  2H0D B;  1X4U A;  4BHW A;  5FEY A;  4LKA A;  3M62 A;  4CA1 A;  2VJE B;  2VP7 A;  4LLB A;  3T6R A;  4C9Z A;  1T1H A;  1MM3 A;  3C5K A;  3KV5 A;  2ECN A;  4BBQ A;  2MA5 A;  4O64 A;  3O7A A;  2LRI C;  4YBT A;  2YYR A;  4YBS A;  2ECW A;  2YW8 A;  1WEU A;  2XB1 A;  2YQM A;  1K2F A;  2LGG A;  3N9P A;  2KU3 A;  4A4C A;  2QIZ A;  2CKL A;  2MUM A;  1WFK A;  4A49 A;  2JMJ A;  2YHN A;  1F62 A;  2VNF A;  2DX8 A;  1LDJ B;  4AUQ B;  2LGL A;  4YAB A;  1HYJ A;  3KNV A;  3O70 A;  3ZTG A;  2YUR A;  4YAD A;  2F42 A;  2KIZ A;  2H0D A;  4IC3 A;  2MNY A;  2LGK A;  2MD7 B;  2AN6 A;  2KR4 A;  2VJE A;  2FUU A;  3N9N A;  2E6R A;  2K17 A;  2L43 A;  5B76 A;  2K1J A;  4GB0 A;  4LK9 A;  2RSD A;  2XEU A;  2BAY A;  4PTB A;  2C2L A;  2YRE A;  4WZ0 A;  4N4F A;  4FO9 A;  1VYX A;  2C2V S;  5J3X A;  3LQJ A;  1RMD A;  3EB6 A;  3SOU A;  2PUY A;  4R7E A;  1XWH A;  5G04 B;  5D1L B;  4PPE A;  4CCG X;  3GV4 A;  4IC2 A;  3NG2 A;  2D8S A;  2LV9 A;  2YHO A;  1MM2 A;  4UI9 B;  3MHH A;  5H1V A;  3SOX A;  2VJF B;  3T7L A;  4AYC B;  4UP0 A;  3ASL A;  2Y43 A;  2K16 A;  4GNF A;  2VPD A;  2MNZ A;  3KV6 A;  5LKX A;  4LAD B;  1U6G B;  5H9M A;  1FBV A;  3RPG B;  5C13 A;  4A0C D;  2CSZ A;  5G05 B;  4WZ2 A;  4Q6F A;  1Z60 A;  4XI1 A;  2Y1M A;  2RI7 A;  5TDR A;  3ZPV E;  2LXH C;  3L1Z B;  1WIM A;  3IHP A;  1WEV A;  1WEE A;  5FER A;  2YSJ A;  2VJF A;  2UZG A;  4AYC A;  3U5N A;  3C6W A;  5KH3 A;  3DPL R;  2F6N A;  3M99 A;  4FJC A;  1WE9 A;  2ECJ A;  1VFY A;  3U5P A;  2L75 A;  3QZV A;  1Z6U A;  2M3H A;  5AIU A;  4V3K C;  1CHC A;  3RTR B;  1X4I A;  2LGV A;  4YC9 A;  2KWN A;  3U5O A;  4GNE A;  2Y1N A;  5B77 A;  4YAT A;  2LN0 A;  2PNX A;  5TRB A;  2VPB A;  4I7B A;  2G45 A;  5KH9 A;  3ZVY A;  4S3O B;  1N87 A;  3RPG C;  2KWK A;  1JOC A;  5FB1 A;  2HDP A;  3HCS A;  2MA6 A;  4GND A;  3O33 A;  4WA6 A;  2KE1 A;  1WEP A;  3PUR A;  5H1U A;  2FSA A;  5EYA F;  2JRJ A;  1VD4 A;  2L5U A;  4I7D A;  5I3L A;  1E4U A;  2KWO A;  4ZQL A;  4P5O B;  2M6M A;  2M85 A;  5H1T A;  3PUQ A;  5LKT A;  2FUI A;  5D1M B;  3ZVZ B;  3HCU A;  5G0F A;  2EA6 A;  2HYE D;  4WZ3 B;  2CT2 A;  3L1X A;  3HCT A;  2LQ6 A;  4R2Y A;  2YU4 A;  1V87 A;  4X3G A;  1WIL A;  2F6J A;  2VPG A;  2M1R A;  3VK6 A;  2G43 A;  3V43 A;  2ECI A;  4B86 C;  2LDR A;  3O35 A;  4YAX A;  3ZYQ A;  2VPE A;  4AVX A;  3O34 A;  4FIP A;  3KQI A;  4S3O C;  1Z2Q A;  2IDA A;  4GNG A;  5LKZ A;  1X4J A;  4F52 B;  3N9O A;  1JM7 B;  4W4U A;  1WEO A;  1DVP A;  2QIC A;  1BOR A;  3DQV R;  2CSY A;  3HTK C;  4UP5 A;  3N9L A;  5AIT A;  5LKU A;  2NAA A;  2OXQ C;  2KFT A;  3LRQ A;  2L80 A;  3SOW A; 
#chains in the Genus database with same CATH topology
 2MD8 C;  5B8D A;  2JMD A;  3ZPV 1;  2EOD A;  4ZUX U;  2DJA A;  5B78 A;  1WEW A;  3LQI A;  2ECV A;  3EB5 A;  4L58 A;  5TAB A;  2I50 A;  2MT5 A;  2KGG A;  5KH7 A;  2YQL A;  2L7P A;  3O36 A;  1WGM A;  4R8P K;  5D1K B;  1JM7 A;  2CSV A;  5B75 A;  2YVR A;  4B7Y C;  4YBM A;  2YUC A;  5LCW B;  4Z0O A;  1IYM A;  5TDW A;  3ZNI A;  4QQ4 A;  1WEN A;  2JMI A;  2ECT A;  3PHD A;  5SVX A;  4QF2 A;  1WEM A;  2L0B A;  1WEQ A;  4MVT A;  2EGP A;  3N9Q A;  2KWJ A;  2YSM A;  2KRE A;  3L11 A;  2K4D A;  2MIQ A;  1FP0 A;  5C11 A;  2ECG A;  4V3L C;  4ZDT A;  3M63 A;  3U5M A;  5TBN A;  3N9M A;  4NN2 A;  1WES A;  4AP4 A;  2LXP C;  2OWA A;  5K3Q A;  4L7X A;  5DKA A;  3MHS A;  1DCQ A;  4A4B A;  3LQH A;  3H7H A;  4QF3 A;  2G6Q A;  3JUE A;  2KGI A;  2YT5 A;  5SVY A;  1G25 A;  2XOZ A;  3GL6 A;  4I7C A;  1ZBD B;  5B79 A;  2FD4 A;  4H9D A;  5JG6 A;  2B0O E;  5DIN A;  3O37 A;  3Q1D A;  4O62 A;  3SHB A;  2QJ0 A;  2CKL B;  2P57 A;  4MSX A;  3I2D A;  4TKP B;  2E61 A;  1LDK C;  2ZET C;  2E6S A;  4N3W A;  4LJN A;  3FL2 A;  5FB0 A;  2KYU A;  1HYI A;  4FK5 A;  2H0D B;  1X4U A;  4BHW A;  3LVR E;  5FEY A;  5SVI B;  4LKA A;  3M62 A;  4CA1 A;  3FAO A;  3MDB C;  2VJE B;  2VP7 A;  4LLB A;  3T6R A;  4C9Z A;  1T1H A;  1MM3 A;  2MKE A;  3C5K A;  3KV5 A;  3O47 A;  2ECN A;  4BBQ A;  2KKX A;  2MA5 A;  4O64 A;  3O7A A;  2LRI C;  4YBT A;  2YYR A;  4OGE A;  4YBS A;  2ECW A;  2YW8 A;  1WEU A;  2XB1 A;  2YQM A;  1K2F A;  2LGG A;  3N9P A;  2KU3 A;  4A4C A;  2QIZ A;  2CKL A;  2MUM A;  1WFK A;  4A49 A;  2JMJ A;  2CON A;  2YHN A;  1F62 A;  2VNF A;  3FAN A;  2DX8 A;  1LDJ B;  3DDT A;  4AUQ B;  2LGL A;  4YAB A;  1HYJ A;  3KNV A;  3O70 A;  3ZTG A;  2YUR A;  4YAD A;  2F42 A;  2KIZ A;  2H0D A;  4IC3 A;  2MNY A;  2LGK A;  2MD7 B;  2AN6 A;  2KR4 A;  2VJE A;  2FUU A;  3N9N A;  2E6R A;  2K17 A;  2L43 A;  5B76 A;  2K1J A;  4GB0 A;  4LK9 A;  2RSD A;  2XEU A;  2BAY A;  4PTB A;  2C2L A;  2YRE A;  4WZ0 A;  4N4F A;  2D8U A;  4FO9 A;  4Z0R A;  1VYX A;  2C2V S;  5J3X A;  3LQJ A;  1RMD A;  3EB6 A;  3SOU A;  3FJU B;  2PUY A;  4R7E A;  1XWH A;  5G04 B;  5D1L B;  3FEH A;  4PPE A;  2LAU A;  4CCG X;  3GV4 A;  4IC2 A;  3NG2 A;  2D8S A;  2LV9 A;  2YHO A;  1MM2 A;  4UI9 B;  3MHH A;  2DSM A;  5H1V A;  4F1P A;  3SOX A;  2VJF B;  3T7L A;  4AYC B;  4UP0 A;  2CRR A;  3M7K A;  3ASL A;  2Y43 A;  2FFW A;  2K16 A;  4GNF A;  2VPD A;  2MNZ A;  3KV6 A;  5LKX A;  4LAD B;  1U6G B;  5H9M A;  1FBV A;  3RPG B;  5C13 A;  4A0C D;  2CSZ A;  5G05 B;  4WZ2 A;  3PLW A;  4Q6F A;  1Z60 A;  4XI1 A;  2Y1M A;  2RI7 A;  5TDR A;  3ZPV E;  2LXH C;  3L1Z B;  1WIM A;  3IHP A;  4OGC A;  1WEV A;  1WEE A;  5FER A;  2YSJ A;  2VJF A;  2UZG A;  4AYC A;  3U5N A;  3C6W A;  5KH3 A;  3DPL R;  2JM3 A;  2F6N A;  3E2D A;  3M99 A;  4FJC A;  1WE9 A;  2ECJ A;  1VFY A;  3U5P A;  2L75 A;  3QZV A;  1Z6U A;  2M3H A;  5AIU A;  4V3K C;  1CHC A;  5SVI A;  3RTR B;  1X4I A;  2LGV A;  4YC9 A;  2KWN A;  3U5O A;  4GNE A;  2Y1N A;  5B77 A;  4YAT A;  2LN0 A;  2PNX A;  5TRB A;  2VPB A;  4I7B A;  2CRW A;  2G45 A;  5KH9 A;  3ZVY A;  4S3O B;  1N87 A;  3RPG C;  2KWK A;  1JOC A;  5FB1 A;  2HDP A;  3HCS A;  2MA6 A;  2M13 A;  4GND A;  2JUN A;  3O33 A;  4WA6 A;  2KE1 A;  1WEP A;  3PUR A;  5H1U A;  2FSA A;  5EYA F;  2JRJ A;  1VD4 A;  2L5U A;  4I7D A;  5I3L A;  1E4U A;  2KWO A;  4ZQL A;  4P5O B;  3DWD A;  2M6M A;  2M85 A;  5H1T A;  3PUQ A;  5LKT A;  2FUI A;  2XOY A;  5D1M B;  3ZVZ B;  3LVQ E;  3HCU A;  5G0F A;  2EA6 A;  2HYE D;  4WZ3 B;  2CT2 A;  3L1X A;  3HCT A;  2LQ6 A;  4R2Y A;  2YU4 A;  2XOC A;  3LJU X;  3KDE C;  1V87 A;  4X3G A;  1WIL A;  2F6J A;  2VPG A;  2M1R A;  3VK6 A;  2G43 A;  3V43 A;  1MBM A;  2ECI A;  4B86 C;  2LDR A;  3O35 A;  4YAX A;  3ZYQ A;  2VPE A;  4AVX A;  3O34 A;  3T9K A;  4FIP A;  3KQI A;  4S3O C;  1Z2Q A;  2IDA A;  3SUB A;  4GNG A;  5LKZ A;  1X4J A;  4F52 B;  3N9O A;  1JM7 B;  4W4U A;  3LDY A;  1WEO A;  3FM8 C;  1DVP A;  2EGM A;  2QIC A;  1BOR A;  3DQV R;  2CSY A;  3HTK C;  4UP5 A;  2IQJ A;  3N9L A;  2RR4 A;  2XP0 A;  5AIT A;  5LKU A;  2NAA A;  2KKY A;  2OXQ C;  2EXU A;  2KFT A;  3LRQ A;  2L80 A;  3SOW A; 
#chains in the Genus database with same CATH homology
 2MD8 C;  5B8D A;  2JMD A;  3ZPV 1;  2EOD A;  4ZUX U;  5B78 A;  1WEW A;  3LQI A;  2ECV A;  3EB5 A;  4L58 A;  5TAB A;  2I50 A;  2MT5 A;  2KGG A;  5KH7 A;  2YQL A;  3O36 A;  1WGM A;  4R8P K;  5D1K B;  1JM7 A;  5B75 A;  4B7Y C;  4YBM A;  2YUC A;  5LCW B;  1IYM A;  5TDW A;  3ZNI A;  1WEN A;  2JMI A;  2ECT A;  3PHD A;  4QF2 A;  1WEM A;  2L0B A;  1WEQ A;  4MVT A;  2EGP A;  3N9Q A;  2KWJ A;  2YSM A;  2KRE A;  3L11 A;  2K4D A;  2MIQ A;  1FP0 A;  5C11 A;  2ECG A;  4V3L C;  4ZDT A;  3M63 A;  3U5M A;  5TBN A;  3N9M A;  4NN2 A;  1WES A;  4AP4 A;  2LXP C;  4L7X A;  5DKA A;  3MHS A;  4A4B A;  3LQH A;  4QF3 A;  2G6Q A;  2KGI A;  2YT5 A;  1G25 A;  3GL6 A;  4I7C A;  1ZBD B;  5B79 A;  5JG6 A;  5DIN A;  3O37 A;  3SHB A;  2QJ0 A;  2CKL B;  4MSX A;  3I2D A;  4TKP B;  1LDK C;  2ZET C;  2E6S A;  4N3W A;  4LJN A;  3FL2 A;  5FB0 A;  2KYU A;  1HYI A;  4FK5 A;  2H0D B;  1X4U A;  4BHW A;  5FEY A;  4LKA A;  3M62 A;  4CA1 A;  2VJE B;  2VP7 A;  4LLB A;  3T6R A;  4C9Z A;  1T1H A;  1MM3 A;  3C5K A;  3KV5 A;  2ECN A;  4BBQ A;  2MA5 A;  4O64 A;  3O7A A;  2LRI C;  4YBT A;  2YYR A;  4YBS A;  2ECW A;  2YW8 A;  1WEU A;  2XB1 A;  2YQM A;  1K2F A;  2LGG A;  3N9P A;  2KU3 A;  4A4C A;  2QIZ A;  2CKL A;  2MUM A;  1WFK A;  4A49 A;  2JMJ A;  2YHN A;  1F62 A;  2VNF A;  2DX8 A;  1LDJ B;  4AUQ B;  2LGL A;  4YAB A;  1HYJ A;  3KNV A;  3O70 A;  3ZTG A;  2YUR A;  4YAD A;  2F42 A;  2KIZ A;  2H0D A;  4IC3 A;  2MNY A;  2LGK A;  2MD7 B;  2AN6 A;  2KR4 A;  2VJE A;  2FUU A;  3N9N A;  2E6R A;  2K17 A;  2L43 A;  5B76 A;  2K1J A;  4GB0 A;  4LK9 A;  2RSD A;  2XEU A;  2BAY A;  4PTB A;  2C2L A;  2YRE A;  4WZ0 A;  4N4F A;  4FO9 A;  1VYX A;  2C2V S;  5J3X A;  3LQJ A;  1RMD A;  3EB6 A;  3SOU A;  2PUY A;  4R7E A;  1XWH A;  5G04 B;  5D1L B;  4PPE A;  4CCG X;  3GV4 A;  4IC2 A;  3NG2 A;  2D8S A;  2LV9 A;  2YHO A;  1MM2 A;  4UI9 B;  3MHH A;  5H1V A;  3SOX A;  2VJF B;  3T7L A;  4AYC B;  4UP0 A;  3ASL A;  2Y43 A;  2K16 A;  4GNF A;  2VPD A;  2MNZ A;  3KV6 A;  5LKX A;  4LAD B;  1U6G B;  5H9M A;  1FBV A;  3RPG B;  5C13 A;  4A0C D;  2CSZ A;  5G05 B;  4WZ2 A;  4Q6F A;  1Z60 A;  4XI1 A;  2Y1M A;  2RI7 A;  5TDR A;  3ZPV E;  2LXH C;  3L1Z B;  1WIM A;  3IHP A;  1WEV A;  1WEE A;  5FER A;  2YSJ A;  2VJF A;  2UZG A;  4AYC A;  3U5N A;  3C6W A;  5KH3 A;  3DPL R;  2F6N A;  3M99 A;  4FJC A;  1WE9 A;  2ECJ A;  1VFY A;  3U5P A;  2L75 A;  3QZV A;  1Z6U A;  2M3H A;  5AIU A;  4V3K C;  1CHC A;  3RTR B;  1X4I A;  2LGV A;  4YC9 A;  2KWN A;  3U5O A;  4GNE A;  2Y1N A;  5B77 A;  4YAT A;  2LN0 A;  2PNX A;  5TRB A;  2VPB A;  4I7B A;  2G45 A;  5KH9 A;  3ZVY A;  4S3O B;  1N87 A;  3RPG C;  2KWK A;  1JOC A;  5FB1 A;  2HDP A;  3HCS A;  2MA6 A;  4GND A;  3O33 A;  4WA6 A;  2KE1 A;  1WEP A;  3PUR A;  5H1U A;  2FSA A;  5EYA F;  2JRJ A;  1VD4 A;  2L5U A;  4I7D A;  5I3L A;  1E4U A;  2KWO A;  4ZQL A;  4P5O B;  2M6M A;  2M85 A;  5H1T A;  3PUQ A;  5LKT A;  2FUI A;  5D1M B;  3ZVZ B;  3HCU A;  5G0F A;  2EA6 A;  2HYE D;  4WZ3 B;  2CT2 A;  3L1X A;  3HCT A;  2LQ6 A;  4R2Y A;  2YU4 A;  1V87 A;  4X3G A;  1WIL A;  2F6J A;  2VPG A;  2M1R A;  3VK6 A;  2G43 A;  3V43 A;  2ECI A;  4B86 C;  2LDR A;  3O35 A;  4YAX A;  3ZYQ A;  2VPE A;  4AVX A;  3O34 A;  4FIP A;  3KQI A;  4S3O C;  1Z2Q A;  2IDA A;  4GNG A;  5LKZ A;  1X4J A;  4F52 B;  3N9O A;  1JM7 B;  4W4U A;  1WEO A;  1DVP A;  2QIC A;  1BOR A;  3DQV R;  2CSY A;  3HTK C;  4UP5 A;  3N9L A;  5AIT A;  5LKU A;  2NAA A;  2OXQ C;  2KFT A;  3LRQ A;  2L80 A;  3SOW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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