2XP0A

C-terminal cysteine-rich domain of human chfr
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
239
structure length
212
Chain Sequence
PYVVCRQCPEYRRQAAQPPHCPDYVCPLQGSHALCTCCFQPMPDRRVEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYESDILKNYLATRGLTWKNMLTESLVALQRGVFLLSDYRVTGDTVLCYCCGLRSFRELTYQYRQNIPASELPVAVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of Poly(Adp-Ribose) Recognition by the Multizinc Binding Domain of Checkpoint with Forkhead-Associated and Ring Domains (Chfr).
pubmed doi rcsb
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE CHFR
molecule tags Ligase
source organism Homo sapiens
total genus 64
structure length 212
sequence length 239
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2010-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF10283 zf-CCHH PBZ domain
A PF17979 zf-CRD Cysteine rich domain with multizinc binding regions
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.140 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Herpes Virus-1 2xp0A01
2XOYA 2XOCA 2XP0A 2XOZA
chains in the Genus database with same CATH superfamily
2L43A 3FEHA 2L0BA 3O70A 2JUNA 3C6WA 4F1PA 3I2DA 4V3LC 2C2LA 5TRBA 2LDRA 4BHWA 2CT2A 3O47A 5FERA 2CSVA 2YYRA 5FB0A 4ZDTA 2MA5A 1WGMA 2DJAA 5TBNA 2DSMA 5H1TA 4S3OB 1V87A 2MA6A 5JG6A 2XEUA 1T1HA 3ZVYA 2VNFA 5DINA 1WEOA 1WILA 2LGLA 3FAOA 2LQ6A 3GV4A 4O64A 1WIMA 2MD7B 5SVIA 1MM2A 2MIQA 5B78A 2Y43A 4WA6A 4YAXA 3N9PA 3MHSA 3RPGB 3ZPVE 2FD4A 5C13A 2M13A 5B75A 4C9ZA 4GB0A 2KWJA 3GL6A 3JUEA 4NN2A 2KKXA 3DQVR 1VFYA 4W4UA 4UP0A 4WZ3B 2VP7A 4R2YA 2CRRA 5G04B 3HCUA 4A0CD 1HYIA 3PHDA 2P57A 2CKLA 4PPEA 4IC3A 2MNZA 5SVXA 1Z2QA 2QJ0A 3O7AA 2KGGA 4FIPA 4BBQA 2RSDA 4PTBA 2ECWA 2YQLA 4Q6FA 2CSZA 1WENA 3O36A 2G45A 3M7KA 2LV9A 4LLBA 4I7DA 4YABA 3E2DA 3O34A 4O62A 5H1UA 2G6QA 3N9MA 5I3LA 4I7CA 2EXUA 4IC2A 4N4FA 3T7LA 2YHNA 3L1ZB 4AYCA 2ECJA 2XOYA 5AIUA 1WEEA 3T9KA 2KE1A 3FM8C 2FFWA 2K17A 2VPBA 1ZBDB 2QIZA 4V3KC 5TABA 3VK6A 4AP4A 2H0DA 2G43A 5K3QA 3KV5A 1CHCA 5KH9A 3SUBA 2KU3A 5B79A 2K16A 2XOZA 1X4IA 3M99A 2NAAA 2KWKA 4UP5A 1K2FA 2VPGA 2YURA 2Y1MA 3NG2A 4F52B 1WEUA 3DPLR 4MSXA 3DDTA 2M3HA 4L7XA 1N87A 5B76A 2JM3A 3U5MA 2KWNA 3QZVA 1LDJB 2VJFB 2CSYA 4X3GA 2JMIA 2MUMA 5TDRA 3U5NA 2CRWA 1WE9A 3U5OA 1WEMA 5J3XA 2I50A 5LKUA 3N9QA 4B86C 2JMJA 2K1JA 4ZQLA 3DWDA 2KGIA 2BAYA 4YBSA 3HCSA 2RI7A 5AITA 2PNXA 4R8PK 1JM7A 3RPGC 2XP0A 2F6NA 1VYXA 2L5UA 2KR4A 4ZUXU 3ZPV1 1X4UA 3LVQE 5LKTA 2YHOA 1FP0A 3EB6A 1LDKC 3T6RA 1VD4A 2KREA 5SVIB 2YREA 3PURA 2FUIA 5H9MA 3L11A 3FJUB 4A49A 2B0OE 2LRIC 4UI9B 3M63A 2EODA 2LXHC 2PUYA 3KQIA 1MM3A 2ECVA 2HYED 2YSJA 1F62A 2CKLB 2XOCA 4QF3A 5D1LB 5B8DA 2F42A 2Y1NA 3LQIA 3O37A 4CCGX 4GNFA 5C11A 4H9DA 1WFKA 3ZVZB 2D8SA 3O35A 2KWOA 2LN0A 4CA1A 1E4UA 4LADB 4N3WA 4L58A 2E6SA 4YBTA 3MHHA 2ZETC 1RMDA 5FB1A 2VJEA 1G25A 3U5PA 5FEYA 3Q1DA 2KYUA 4YADA 4AYCB 2OWAA 2KKYA 3M62A 3O33A 2MKEA 4A4BA 3LQHA 1BORA 4YATA 3N9OA 2JMDA 3MDBC 5DKAA 3N9NA 4WZ2A 2RR4A 4YBMA 2OXQC 1Z6UA 2H0DB 3C5KA 3KDEC 4A4CA 4QF2A 2LGGA 2F6JA 3LRQA 3V43A 1XWHA 3RTRB 3KNVA 2LGVA 5LCWB 3LDYA 2EA6A 3SHBA 4S3OC 4OGEA 2EGMA 2YQMA 3IHPA 2ECTA 4LK9A 2M1RA 4FJCA 4GNDA 4R7EA 5KH7A 2KIZA 1DCQA 2E6RA 2VPDA 4OGCA 4LJNA 2C2VS 2IQJA 3LQJA 2L75A 1MBMA 4GNGA 2M85A 4FO9A 2ECIA 1WEPA 4AVXA 2ECGA 2YW8A 1JM7B 2VPEA 5LKZA 1WEQA 3KV6A 5H1VA 2DX8A 3FANA 3SOUA 1WEWA 2MD8C 2YU4A 2LGKA 2M6MA 3EB5A 2MT5A 2QICA 4Z0RA 2KFTA 3ZYQA 3L1XA 1HYJA 2EGPA 1FBVA 3ZTGA 4YC9A 2ECNA 4AUQB 2L7PA 4XI1A 5G0FA 2IDAA 3HCTA 2YUCA 1DVPA 2YSMA 4I7BA 4GNEA 2E61A 2FSAA 4MVTA 2LXPC 2HDPA 3PLWA 1U6GB 2AN6A 4QQ4A 4WZ0A 4B7YC 4Z0OA 3HTKC 5LKXA 1JOCA 5EYAF 3LJUX 2FUUA 3ASLA 2LAUA 2L80A 3SOXA 5SVYA 2CONA 3ZNIA 1WEVA 2YVRA 5G05B 4TKPB 1Z60A 1WESA 2JRJA 2VJEB 4FK5A 3N9LA 3PUQA 1X4JA 5KH3A 4P5OB 2D8UA 2MNYA 5B77A 4LKAA 3SOWA 2YT5A 2K4DA 1IYMA 5D1MB 2UZGA 3H7HA 5D1KB 2XB1A 5TDWA 3FL2A 3LVRE 2VJFA
chains in the Genus database with same CATH topology
2IQJA 3FEHA 2M13A 3LDYA 3LVQE 3MDBC 2DJAA 3JUEA 2XOYA 2KKXA 2JUNA 2E61A 3M7KA 4F1PA 2RR4A 3DDTA 4OGEA 3T9KA 3FM8C 2FFWA 3PLWA 2EGMA 4QQ4A 5SVIB 2D8UA 2JM3A 3DWDA 2XOCA 2YREA 3E2DA 4O62A 4Z0OA 3KDEC 4Z0RA 2CRRA 3Q1DA 3LJUX 3O47A 2EXUA 2P57A 5SVIA 1DCQA 2CSVA 2LAUA 2OWAA 3FJUB 5SVXA 2XOZA 3H7HA 2KKYA 4OGCA 5K3QA 2CONA 2B0OE 5SVYA 3SUBA 2XP0A 2L7PA 2CRWA 2FD4A 3LVRE 2MKEA 2YVRA 4H9DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XOY A;  2XOC A;  2XP0 A;  2XOZ A; 
#chains in the Genus database with same CATH topology
 2L43 A;  3FEH A;  2L0B A;  3O70 A;  2JUN A;  3C6W A;  4F1P A;  3I2D A;  4V3L C;  2C2L A;  5TRB A;  2LDR A;  4BHW A;  2CT2 A;  3O47 A;  5FER A;  2CSV A;  2YYR A;  5FB0 A;  4ZDT A;  2MA5 A;  1WGM A;  2DJA A;  5TBN A;  2DSM A;  5H1T A;  4S3O B;  1V87 A;  2MA6 A;  5JG6 A;  2XEU A;  1T1H A;  3ZVY A;  2VNF A;  5DIN A;  1WEO A;  1WIL A;  2LGL A;  3FAO A;  2LQ6 A;  3GV4 A;  4O64 A;  1WIM A;  2MD7 B;  5SVI A;  1MM2 A;  2MIQ A;  5B78 A;  2Y43 A;  4WA6 A;  4YAX A;  3N9P A;  3MHS A;  3RPG B;  3ZPV E;  2FD4 A;  5C13 A;  2M13 A;  5B75 A;  4C9Z A;  4GB0 A;  2KWJ A;  3GL6 A;  3JUE A;  4NN2 A;  2KKX A;  3DQV R;  1VFY A;  4W4U A;  4UP0 A;  4WZ3 B;  2VP7 A;  4R2Y A;  2CRR A;  5G04 B;  3HCU A;  4A0C D;  1HYI A;  3PHD A;  2P57 A;  2CKL A;  4PPE A;  4IC3 A;  2MNZ A;  5SVX A;  1Z2Q A;  2QJ0 A;  3O7A A;  2KGG A;  4FIP A;  4BBQ A;  2RSD A;  4PTB A;  2ECW A;  2YQL A;  4Q6F A;  2CSZ A;  1WEN A;  3O36 A;  2G45 A;  3M7K A;  2LV9 A;  4LLB A;  4I7D A;  4YAB A;  3E2D A;  3O34 A;  4O62 A;  5H1U A;  2G6Q A;  3N9M A;  5I3L A;  4I7C A;  2EXU A;  4IC2 A;  4N4F A;  3T7L A;  2YHN A;  3L1Z B;  4AYC A;  2ECJ A;  2XOY A;  5AIU A;  1WEE A;  3T9K A;  2KE1 A;  3FM8 C;  2FFW A;  2K17 A;  2VPB A;  1ZBD B;  2QIZ A;  4V3K C;  5TAB A;  3VK6 A;  4AP4 A;  2H0D A;  2G43 A;  5K3Q A;  3KV5 A;  1CHC A;  5KH9 A;  3SUB A;  2KU3 A;  5B79 A;  2K16 A;  2XOZ A;  1X4I A;  3M99 A;  2NAA A;  2KWK A;  4UP5 A;  1K2F A;  2VPG A;  2YUR A;  2Y1M A;  3NG2 A;  4F52 B;  1WEU A;  3DPL R;  4MSX A;  3DDT A;  2M3H A;  4L7X A;  1N87 A;  5B76 A;  2JM3 A;  3U5M A;  2KWN A;  3QZV A;  1LDJ B;  2VJF B;  2CSY A;  4X3G A;  2JMI A;  2MUM A;  5TDR A;  3U5N A;  2CRW A;  1WE9 A;  3U5O A;  1WEM A;  5J3X A;  2I50 A;  5LKU A;  3N9Q A;  4B86 C;  2JMJ A;  2K1J A;  4ZQL A;  3DWD A;  2KGI A;  2BAY A;  4YBS A;  3HCS A;  2RI7 A;  5AIT A;  2PNX A;  4R8P K;  1JM7 A;  3RPG C;  2XP0 A;  2F6N A;  1VYX A;  2L5U A;  2KR4 A;  4ZUX U;  3ZPV 1;  1X4U A;  3LVQ E;  5LKT A;  2YHO A;  1FP0 A;  3EB6 A;  1LDK C;  3T6R A;  1VD4 A;  2KRE A;  5SVI B;  2YRE A;  3PUR A;  2FUI A;  5H9M A;  3L11 A;  3FJU B;  4A49 A;  2B0O E;  2LRI C;  4UI9 B;  3M63 A;  2EOD A;  2LXH C;  2PUY A;  3KQI A;  1MM3 A;  2ECV A;  2HYE D;  2YSJ A;  1F62 A;  2CKL B;  2XOC A;  4QF3 A;  5D1L B;  5B8D A;  2F42 A;  2Y1N A;  3LQI A;  3O37 A;  4CCG X;  4GNF A;  5C11 A;  4H9D A;  1WFK A;  3ZVZ B;  2D8S A;  3O35 A;  2KWO A;  2LN0 A;  4CA1 A;  1E4U A;  4LAD B;  4N3W A;  4L58 A;  2E6S A;  4YBT A;  3MHH A;  2ZET C;  1RMD A;  5FB1 A;  2VJE A;  1G25 A;  3U5P A;  5FEY A;  3Q1D A;  2KYU A;  4YAD A;  4AYC B;  2OWA A;  2KKY A;  3M62 A;  3O33 A;  2MKE A;  4A4B A;  3LQH A;  1BOR A;  4YAT A;  3N9O A;  2JMD A;  3MDB C;  5DKA A;  3N9N A;  4WZ2 A;  2RR4 A;  4YBM A;  2OXQ C;  1Z6U A;  2H0D B;  3C5K A;  3KDE C;  4A4C A;  4QF2 A;  2LGG A;  2F6J A;  3LRQ A;  3V43 A;  1XWH A;  3RTR B;  3KNV A;  2LGV A;  5LCW B;  3LDY A;  2EA6 A;  3SHB A;  4S3O C;  4OGE A;  2EGM A;  2YQM A;  3IHP A;  2ECT A;  4LK9 A;  2M1R A;  4FJC A;  4GND A;  4R7E A;  5KH7 A;  2KIZ A;  1DCQ A;  2E6R A;  2VPD A;  4OGC A;  4LJN A;  2C2V S;  2IQJ A;  3LQJ A;  2L75 A;  1MBM A;  4GNG A;  2M85 A;  4FO9 A;  2ECI A;  1WEP A;  4AVX A;  2ECG A;  2YW8 A;  1JM7 B;  2VPE A;  5LKZ A;  1WEQ A;  3KV6 A;  5H1V A;  2DX8 A;  3FAN A;  3SOU A;  1WEW A;  2MD8 C;  2YU4 A;  2LGK A;  2M6M A;  3EB5 A;  2MT5 A;  2QIC A;  4Z0R A;  2KFT A;  3ZYQ A;  3L1X A;  1HYJ A;  2EGP A;  1FBV A;  3ZTG A;  4YC9 A;  2ECN A;  4AUQ B;  2L7P A;  4XI1 A;  5G0F A;  2IDA A;  3HCT A;  2YUC A;  1DVP A;  2YSM A;  4I7B A;  4GNE A;  2E61 A;  2FSA A;  4MVT A;  2LXP C;  2HDP A;  3PLW A;  1U6G B;  2AN6 A;  4QQ4 A;  4WZ0 A;  4B7Y C;  4Z0O A;  3HTK C;  5LKX A;  1JOC A;  5EYA F;  3LJU X;  2FUU A;  3ASL A;  2LAU A;  2L80 A;  3SOX A;  5SVY A;  2CON A;  3ZNI A;  1WEV A;  2YVR A;  5G05 B;  4TKP B;  1Z60 A;  1WES A;  2JRJ A;  2VJE B;  4FK5 A;  3N9L A;  3PUQ A;  1X4J A;  5KH3 A;  4P5O B;  2D8U A;  2MNY A;  5B77 A;  4LKA A;  3SOW A;  2YT5 A;  2K4D A;  1IYM A;  5D1M B;  2UZG A;  3H7H A;  5D1K B;  2XB1 A;  5TDW A;  3FL2 A;  3LVR E;  2VJF A; 
#chains in the Genus database with same CATH homology
 2IQJ A;  3FEH A;  2M13 A;  3LDY A;  3LVQ E;  3MDB C;  2DJA A;  3JUE A;  2XOY A;  2KKX A;  2JUN A;  2E61 A;  3M7K A;  4F1P A;  2RR4 A;  3DDT A;  4OGE A;  3T9K A;  3FM8 C;  2FFW A;  3PLW A;  2EGM A;  4QQ4 A;  5SVI B;  2D8U A;  2JM3 A;  3DWD A;  2XOC A;  2YRE A;  3E2D A;  4O62 A;  4Z0O A;  3KDE C;  4Z0R A;  2CRR A;  3Q1D A;  3LJU X;  3O47 A;  2EXU A;  2P57 A;  5SVI A;  1DCQ A;  2CSV A;  2LAU A;  2OWA A;  3FJU B;  5SVX A;  2XOZ A;  3H7H A;  2KKY A;  4OGC A;  5K3Q A;  2CON A;  2B0O E;  5SVY A;  3SUB A;  2XP0 A;  2L7P A;  2CRW A;  2FD4 A;  3LVR E;  2MKE A;  2YVR A;  4H9D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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