2VJFA

Crystal structure of the mdm2-mdmx ring domain heterodimer
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
64
structure length
64
Chain Sequence
SSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the Mdm2/Mdmx Ring Domain Heterodimer Reveals Dimerization is Required for Their Ubiquitylation in Trans.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE MDM2
total genus 14
structure length 64
sequence length 64
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2007-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13920 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.10 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Zinc/RING finger domain, C3HC4 (zinc finger) 2vjfA00
2YUCA 5B78A 1HYIA 5LKUA 3HTKC 4P5OB 3RPGB 5TDRA 3KV6A 2JRJA 2M85A 2KE1A 2LGVA 3O70A 2YURA 1V87A 2YSJA 1WEMA 5AITA 1MM3A 4GB0A 1N87A 5H1VA 3ASLA 3GL6A 1WEPA 5DINA 3KNVA 2ECTA 2VPEA 2FSAA 5FEYA 2MNYA 3U5NA 2LRIC 3O33A 5AIUA 2JMJA 4UP5A 1WEWA 2KWNA 2XB1A 2M3HA 5C13A 3LRQA 3PURA 2NAAA 2Y43A 2VPGA 3LQIA 5C11A 2L80A 2E6RA 2QJ0A 4AYCA 4R2YA 4UP0A 5H9MA 5I3LA 1BORA 3O7AA 3EB6A 1WIMA 2ECIA 3ZYQA 4YAXA 2MD7B 3N9QA 1WEUA 2KWKA 2CT2A 4GNGA 3ZTGA 1VD4A 3QZVA 2YSMA 3MHSA 2FUIA 3SOXA 4L58A 1ZBDB 2VJFA 3HCSA 5B77A 5B75A 4GNEA 2CSZA 2EODA 4I7CA 5B79A 3M63A 5TBNA 1Z60A 2YU4A 4AYCB 3ZNIA 3L1XA 2C2VS 4IC2A 4WA6A 5LKXA 1T1HA 2D8SA 1E4UA 1RMDA 2YYRA 2KR4A 4GNFA 4IC3A 4MVTA 2AN6A 4FK5A 3I2DA 1Z2QA 1X4JA 2LXHC 5TRBA 2JMIA 2LV9A 2CKLA 2HYED 3N9MA 5LKZA 2FUUA 3N9PA 5TDWA 4A4BA 2G45A 2G43A 3T7LA 4TKPB 5B8DA 1JOCA 4LADB 2KIZA 4AUQB 3C5KA 3PHDA 2L0BA 2VJFB 5H1TA 3ZVZB 1WEEA 2JMDA 4QF3A 1X4UA 2MT5A 3U5PA 1WESA 3SOWA 3SOUA 2VJEA 1LDJB 4XI1A 2YT5A 5KH3A 4N4FA 2MUMA 4O64A 2LN0A 2KGGA 4R8PK 2MD8C 3T6RA 1F62A 5KH9A 2ECVA 4LJNA 1DVPA 3RTRB 2XEUA 2M1RA 2PNXA 4R7EA 1WEOA 2CKLB 2MNZA 2DX8A 3FL2A 1U6GB 2KFTA 2ECNA 2G6QA 2EGPA 4S3OC 1HYJA 4FIPA 4X3GA 3O34A 3M62A 2Y1NA 2I50A 2LDRA 4A4CA 3ZVYA 2KYUA 2RSDA 2VJEB 1WEQA 1IYMA 3N9NA 2L75A 2ZETC 3KQIA 5D1LB 3KV5A 1K2FA 2Y1MA 5LKTA 5D1KB 1FBVA 5DKAA 4B7YC 2LGKA 2MA6A 4V3LC 2OXQC 4YATA 2L43A 2F6NA 1WGMA 5G04B 5TABA 2LGLA 3ZPVE 2KWOA 5FB1A 4YC9A 3NG2A 2YW8A 2YQLA 5FB0A 2E6SA 3O35A 3L11A 4L7XA 4BHWA 4WZ0A 2K1JA 2K17A 2RI7A 2LQ6A 2QICA 2H0DA 4YBTA 2KU3A 2K16A 3DPLR 4BBQA 5B76A 4WZ3B 3M99A 2KGIA 4NN2A 4AVXA 3LQHA 4LLBA 4A49A 4C9ZA 4F52B 4YBSA 2YHOA 2F42A 4LK9A 4W4UA 4B86C 5FERA 1WEVA 4S3OB 4AP4A 2KWJA 2BAYA 2CSYA 4ZDTA 3O37A 1WFKA 3C6WA 3U5OA 4PPEA 4CA1A 4I7BA 2VP7A 3HCTA 1Z6UA 1XWHA 3LQJA 4I7DA 5G0FA 4Q6FA 3PUQA 4YADA 3HCUA 5LCWB 4ZQLA 1JM7B 2H0DB 2HDPA 4PTBA 4MSXA 5J3XA 2UZGA 2MIQA 1WENA 2KREA 2C2LA 3DQVR 5G05B 2F6JA 3L1ZB 5D1MB 4GNDA 2YREA 4V3KC 4YABA 3RPGC 4QF2A 3N9OA 2VPBA 4LKAA 4FJCA 4YBMA 2LXPC 2L5UA 3SHBA 2VPDA 4WZ2A 1FP0A 2EA6A 5JG6A 1MM2A 3O36A 1VFYA 1WILA 1CHCA 3IHPA 2K4DA 3U5MA 1LDKC 5EYAF 2ECGA 3MHHA 2LGGA 4ZUXU 2PUYA 2M6MA 1X4IA 2YQMA 1G25A 2ECWA 3GV4A 3V43A 2VNFA 3ZPV1 4CCGX 4FO9A 5KH7A 2QIZA 4UI9B 2MA5A 4A0CD 1VYXA 1JM7A 2IDAA 5H1UA 3VK6A 3EB5A 1WE9A 2ECJA 3N9LA 4N3WA 2YHNA
chains in the Genus database with same CATH superfamily
2YUCA 5B78A 1HYIA 5LKUA 3HTKC 4P5OB 3RPGB 5TDRA 3KV6A 2JRJA 3KDEC 2M85A 2KE1A 2LGVA 3O70A 2YURA 1V87A 2YSJA 3Q1DA 1WEMA 5AITA 1MM3A 4GB0A 1N87A 5H1VA 3ASLA 3GL6A 1WEPA 5DINA 3LVRE 3KNVA 2ECTA 2VPEA 2FSAA 5FEYA 2MNYA 3U5NA 2LRIC 3O33A 4OGCA 5AIUA 2JMJA 4UP5A 1WEWA 2KWNA 2XB1A 2M3HA 5C13A 3LRQA 2XOCA 3PURA 2NAAA 3LQIA 2VPGA 2Y43A 5C11A 2L80A 2E6RA 2QJ0A 4AYCA 4R2YA 4UP0A 5H9MA 5I3LA 1BORA 2CRWA 3O7AA 3EB6A 1WIMA 2ECIA 3ZYQA 4YAXA 2DSMA 2MD7B 3N9QA 1WEUA 2KWKA 2CT2A 4GNGA 3ZTGA 2YVRA 3DDTA 1VD4A 2B0OE 3QZVA 2YSMA 3MHSA 2FUIA 3SOXA 4L58A 1ZBDB 2VJFA 3HCSA 3FANA 5B75A 5B77A 4GNEA 2CSZA 2EODA 4I7CA 5B79A 3M63A 5TBNA 3T9KA 1Z60A 3DWDA 2YU4A 4AYCB 3ZNIA 3L1XA 2C2VS 4IC2A 4WA6A 5LKXA 1T1HA 2XP0A 2D8SA 1E4UA 1RMDA 2YYRA 5SVIA 2KR4A 2EGMA 4GNFA 4IC3A 4MVTA 2AN6A 4FK5A 3LJUX 3I2DA 1Z2QA 1X4JA 2LXHC 2L7PA 5TRBA 2JMIA 2LV9A 2CKLA 2FFWA 2HYED 3N9MA 5LKZA 2FUUA 2RR4A 3N9PA 5TDWA 4A4BA 2G45A 2G43A 3T7LA 2M13A 4TKPB 1JOCA 5B8DA 4LADB 2KIZA 4AUQB 3C5KA 3PHDA 2L0BA 4F1PA 2E61A 2VJFB 5H1TA 3ZVZB 1WEEA 2JMDA 4QF3A 1X4UA 2MT5A 3U5PA 1WESA 3SOWA 3O47A 3SOUA 2VJEA 1LDJB 4XI1A 2YT5A 5SVIB 5KH3A 4N4FA 2MUMA 4O64A 2LN0A 2KGGA 4R8PK 3FAOA 3FM8C 2MD8C 3T6RA 1F62A 4QQ4A 5KH9A 2ECVA 4LJNA 1DVPA 3PLWA 3RTRB 2CSVA 2XEUA 2M1RA 4R7EA 2PNXA 2XOYA 3H7HA 1WEOA 5K3QA 2CKLB 2MNZA 2DX8A 3FL2A 2CONA 1U6GB 2JM3A 2KFTA 2ECNA 2G6QA 2EGPA 4S3OC 1HYJA 4FIPA 4X3GA 3O34A 3M62A 2Y1NA 2I50A 4H9DA 2LDRA 4Z0RA 4A4CA 3ZVYA 2KYUA 2RSDA 2VJEB 1WEQA 1IYMA 3N9NA 2L75A 1MBMA 2ZETC 3KQIA 5D1LB 3KV5A 2KKXA 1K2FA 2Y1MA 5LKTA 5D1KB 1FBVA 5DKAA 4B7YC 2LGKA 2MA6A 4V3LC 3LVQE 2OXQC 3MDBC 2XOZA 4YATA 2L43A 2F6NA 1WGMA 5G04B 5TABA 2LGLA 3ZPVE 2KWOA 5FB1A 4YC9A 3NG2A 2YW8A 2YQLA 5FB0A 2E6SA 3O35A 3L11A 4L7XA 4BHWA 4WZ0A 2K1JA 2K17A 2RI7A 2LQ6A 2QICA 2H0DA 4YBTA 3LDYA 2KU3A 2LAUA 2K16A 3DPLR 4BBQA 5SVYA 5B76A 4WZ3B 3M99A 2KGIA 4NN2A 3FJUB 4AVXA 4O62A 3LQHA 4LLBA 4A49A 4C9ZA 4F52B 4YBSA 2YHOA 2F42A 4LK9A 4W4UA 4B86C 5FERA 1WEVA 4S3OB 4AP4A 2KWJA 2BAYA 2CSYA 4ZDTA 2DJAA 3O37A 1WFKA 3C6WA 3U5OA 4PPEA 4CA1A 2D8UA 4I7BA 2VP7A 3FEHA 3HCTA 1Z6UA 1DCQA 1XWHA 3LQJA 4I7DA 4YADA 4Q6FA 3PUQA 4ZQLA 3HCUA 5G0FA 2MKEA 5LCWB 2H0DB 2HDPA 4PTBA 1JM7B 4MSXA 5J3XA 3E2DA 2UZGA 2MIQA 1WENA 2KREA 2C2LA 3DQVR 5G05B 2F6JA 3L1ZB 5D1MB 2P57A 4GNDA 2YREA 5SVXA 4V3KC 4YABA 3RPGC 2IQJA 4QF2A 3N9OA 2VPBA 4LKAA 4FJCA 4YBMA 4Z0OA 3M7KA 2LXPC 2L5UA 3SHBA 2VPDA 4WZ2A 1FP0A 2EXUA 2CRRA 2EA6A 5JG6A 1MM2A 3O36A 2OWAA 1VFYA 1WILA 3JUEA 1CHCA 3IHPA 2K4DA 3U5MA 1LDKC 5EYAF 2ECGA 3MHHA 2LGGA 4ZUXU 2KKYA 2PUYA 2M6MA 1X4IA 2YQMA 1G25A 2ECWA 3GV4A 3V43A 4OGEA 2VNFA 3ZPV1 4CCGX 4FO9A 5KH7A 2QIZA 4UI9B 2MA5A 2FD4A 4A0CD 1VYXA 1JM7A 3SUBA 2IDAA 5H1UA 3VK6A 2JUNA 3EB5A 1WE9A 2ECJA 3N9LA 4N3WA 2YHNA
chains in the Genus database with same CATH topology
2YUCA 5B78A 1HYIA 5LKUA 3HTKC 4P5OB 3RPGB 5TDRA 3KV6A 2JRJA 2M85A 2KE1A 2LGVA 3O70A 2YURA 1V87A 2YSJA 1WEMA 5AITA 1MM3A 4GB0A 1N87A 5H1VA 3ASLA 3GL6A 1WEPA 5DINA 3KNVA 2ECTA 2VPEA 2FSAA 5FEYA 2MNYA 3U5NA 2LRIC 3O33A 5AIUA 2JMJA 4UP5A 1WEWA 2KWNA 2XB1A 2M3HA 5C13A 3LRQA 3PURA 2NAAA 2Y43A 2VPGA 3LQIA 5C11A 2L80A 2E6RA 2QJ0A 4AYCA 4R2YA 4UP0A 5H9MA 5I3LA 1BORA 3O7AA 3EB6A 1WIMA 2ECIA 3ZYQA 4YAXA 2MD7B 3N9QA 1WEUA 2KWKA 2CT2A 4GNGA 3ZTGA 1VD4A 3QZVA 2YSMA 3MHSA 2FUIA 3SOXA 4L58A 1ZBDB 2VJFA 3HCSA 5B77A 5B75A 4GNEA 2CSZA 2EODA 4I7CA 5B79A 3M63A 5TBNA 1Z60A 2YU4A 4AYCB 3ZNIA 3L1XA 2C2VS 4IC2A 4WA6A 5LKXA 1T1HA 2D8SA 1E4UA 1RMDA 2YYRA 2KR4A 4GNFA 4IC3A 4MVTA 2AN6A 4FK5A 3I2DA 1Z2QA 1X4JA 2LXHC 5TRBA 2JMIA 2LV9A 2CKLA 2HYED 3N9MA 5LKZA 2FUUA 3N9PA 5TDWA 4A4BA 2G45A 2G43A 3T7LA 4TKPB 5B8DA 1JOCA 4LADB 2KIZA 4AUQB 3C5KA 3PHDA 2L0BA 2VJFB 5H1TA 3ZVZB 1WEEA 2JMDA 4QF3A 1X4UA 2MT5A 3U5PA 1WESA 3SOWA 3SOUA 2VJEA 1LDJB 4XI1A 2YT5A 5KH3A 4N4FA 2MUMA 4O64A 2LN0A 2KGGA 4R8PK 2MD8C 3T6RA 1F62A 5KH9A 2ECVA 4LJNA 1DVPA 3RTRB 2XEUA 2M1RA 2PNXA 4R7EA 1WEOA 2CKLB 2MNZA 2DX8A 3FL2A 1U6GB 2KFTA 2ECNA 2G6QA 2EGPA 4S3OC 1HYJA 4FIPA 4X3GA 3O34A 3M62A 2Y1NA 2I50A 2LDRA 4A4CA 3ZVYA 2KYUA 2RSDA 2VJEB 1WEQA 1IYMA 3N9NA 2L75A 2ZETC 3KQIA 5D1LB 3KV5A 1K2FA 2Y1MA 5LKTA 5D1KB 1FBVA 5DKAA 4B7YC 2LGKA 2MA6A 4V3LC 2OXQC 4YATA 2L43A 2F6NA 1WGMA 5G04B 5TABA 2LGLA 3ZPVE 2KWOA 5FB1A 4YC9A 3NG2A 2YW8A 2YQLA 5FB0A 2E6SA 3O35A 3L11A 4L7XA 4BHWA 4WZ0A 2K1JA 2K17A 2RI7A 2LQ6A 2QICA 2H0DA 4YBTA 2KU3A 2K16A 3DPLR 4BBQA 5B76A 4WZ3B 3M99A 2KGIA 4NN2A 4AVXA 3LQHA 4LLBA 4A49A 4C9ZA 4F52B 4YBSA 2YHOA 2F42A 4LK9A 4W4UA 4B86C 5FERA 1WEVA 4S3OB 4AP4A 2KWJA 2BAYA 2CSYA 4ZDTA 3O37A 1WFKA 3C6WA 3U5OA 4PPEA 4CA1A 4I7BA 2VP7A 3HCTA 1Z6UA 1XWHA 3LQJA 4I7DA 5G0FA 4Q6FA 3PUQA 4YADA 3HCUA 5LCWB 4ZQLA 1JM7B 2H0DB 2HDPA 4PTBA 4MSXA 5J3XA 2UZGA 2MIQA 1WENA 2KREA 2C2LA 3DQVR 5G05B 2F6JA 3L1ZB 5D1MB 4GNDA 2YREA 4V3KC 4YABA 3RPGC 4QF2A 3N9OA 2VPBA 4LKAA 4FJCA 4YBMA 2LXPC 2L5UA 3SHBA 2VPDA 4WZ2A 1FP0A 2EA6A 5JG6A 1MM2A 3O36A 1VFYA 1WILA 1CHCA 3IHPA 2K4DA 3U5MA 1LDKC 5EYAF 2ECGA 3MHHA 2LGGA 4ZUXU 2PUYA 2M6MA 1X4IA 2YQMA 1G25A 2ECWA 3GV4A 3V43A 2VNFA 3ZPV1 4CCGX 4FO9A 5KH7A 2QIZA 4UI9B 2MA5A 4A0CD 1VYXA 1JM7A 2IDAA 5H1UA 3VK6A 3EB5A 1WE9A 2ECJA 3N9LA 4N3WA 2YHNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YUC A;  5B78 A;  1HYI A;  5LKU A;  3HTK C;  4P5O B;  3RPG B;  5TDR A;  3KV6 A;  2JRJ A;  2M85 A;  2KE1 A;  2LGV A;  3O70 A;  2YUR A;  1V87 A;  2YSJ A;  1WEM A;  5AIT A;  1MM3 A;  4GB0 A;  1N87 A;  5H1V A;  3ASL A;  3GL6 A;  1WEP A;  5DIN A;  3KNV A;  2ECT A;  2VPE A;  2FSA A;  5FEY A;  2MNY A;  3U5N A;  2LRI C;  3O33 A;  5AIU A;  2JMJ A;  4UP5 A;  1WEW A;  2KWN A;  2XB1 A;  2M3H A;  5C13 A;  3LRQ A;  3PUR A;  2NAA A;  2Y43 A;  2VPG A;  3LQI A;  5C11 A;  2L80 A;  2E6R A;  2QJ0 A;  4AYC A;  4R2Y A;  4UP0 A;  5H9M A;  5I3L A;  1BOR A;  3O7A A;  3EB6 A;  1WIM A;  2ECI A;  3ZYQ A;  4YAX A;  2MD7 B;  3N9Q A;  1WEU A;  2KWK A;  2CT2 A;  4GNG A;  3ZTG A;  1VD4 A;  3QZV A;  2YSM A;  3MHS A;  2FUI A;  3SOX A;  4L58 A;  1ZBD B;  2VJF A;  3HCS A;  5B77 A;  5B75 A;  4GNE A;  2CSZ A;  2EOD A;  4I7C A;  5B79 A;  3M63 A;  5TBN A;  1Z60 A;  2YU4 A;  4AYC B;  3ZNI A;  3L1X A;  2C2V S;  4IC2 A;  4WA6 A;  5LKX A;  1T1H A;  2D8S A;  1E4U A;  1RMD A;  2YYR A;  2KR4 A;  4GNF A;  4IC3 A;  4MVT A;  2AN6 A;  4FK5 A;  3I2D A;  1Z2Q A;  1X4J A;  2LXH C;  5TRB A;  2JMI A;  2LV9 A;  2CKL A;  2HYE D;  3N9M A;  5LKZ A;  2FUU A;  3N9P A;  5TDW A;  4A4B A;  2G45 A;  2G43 A;  3T7L A;  4TKP B;  5B8D A;  1JOC A;  4LAD B;  2KIZ A;  4AUQ B;  3C5K A;  3PHD A;  2L0B A;  2VJF B;  5H1T A;  3ZVZ B;  1WEE A;  2JMD A;  4QF3 A;  1X4U A;  2MT5 A;  3U5P A;  1WES A;  3SOW A;  3SOU A;  2VJE A;  1LDJ B;  4XI1 A;  2YT5 A;  5KH3 A;  4N4F A;  2MUM A;  4O64 A;  2LN0 A;  2KGG A;  4R8P K;  2MD8 C;  3T6R A;  1F62 A;  5KH9 A;  2ECV A;  4LJN A;  1DVP A;  3RTR B;  2XEU A;  2M1R A;  2PNX A;  4R7E A;  1WEO A;  2CKL B;  2MNZ A;  2DX8 A;  3FL2 A;  1U6G B;  2KFT A;  2ECN A;  2G6Q A;  2EGP A;  4S3O C;  1HYJ A;  4FIP A;  4X3G A;  3O34 A;  3M62 A;  2Y1N A;  2I50 A;  2LDR A;  4A4C A;  3ZVY A;  2KYU A;  2RSD A;  2VJE B;  1WEQ A;  1IYM A;  3N9N A;  2L75 A;  2ZET C;  3KQI A;  5D1L B;  3KV5 A;  1K2F A;  2Y1M A;  5LKT A;  5D1K B;  1FBV A;  5DKA A;  4B7Y C;  2LGK A;  2MA6 A;  4V3L C;  2OXQ C;  4YAT A;  2L43 A;  2F6N A;  1WGM A;  5G04 B;  5TAB A;  2LGL A;  3ZPV E;  2KWO A;  5FB1 A;  4YC9 A;  3NG2 A;  2YW8 A;  2YQL A;  5FB0 A;  2E6S A;  3O35 A;  3L11 A;  4L7X A;  4BHW A;  4WZ0 A;  2K1J A;  2K17 A;  2RI7 A;  2LQ6 A;  2QIC A;  2H0D A;  4YBT A;  2KU3 A;  2K16 A;  3DPL R;  4BBQ A;  5B76 A;  4WZ3 B;  3M99 A;  2KGI A;  4NN2 A;  4AVX A;  3LQH A;  4LLB A;  4A49 A;  4C9Z A;  4F52 B;  4YBS A;  2YHO A;  2F42 A;  4LK9 A;  4W4U A;  4B86 C;  5FER A;  1WEV A;  4S3O B;  4AP4 A;  2KWJ A;  2BAY A;  2CSY A;  4ZDT A;  3O37 A;  1WFK A;  3C6W A;  3U5O A;  4PPE A;  4CA1 A;  4I7B A;  2VP7 A;  3HCT A;  1Z6U A;  1XWH A;  3LQJ A;  4I7D A;  5G0F A;  4Q6F A;  3PUQ A;  4YAD A;  3HCU A;  5LCW B;  4ZQL A;  1JM7 B;  2H0D B;  2HDP A;  4PTB A;  4MSX A;  5J3X A;  2UZG A;  2MIQ A;  1WEN A;  2KRE A;  2C2L A;  3DQV R;  5G05 B;  2F6J A;  3L1Z B;  5D1M B;  4GND A;  2YRE A;  4V3K C;  4YAB A;  3RPG C;  4QF2 A;  3N9O A;  2VPB A;  4LKA A;  4FJC A;  4YBM A;  2LXP C;  2L5U A;  3SHB A;  2VPD A;  4WZ2 A;  1FP0 A;  2EA6 A;  5JG6 A;  1MM2 A;  3O36 A;  1VFY A;  1WIL A;  1CHC A;  3IHP A;  2K4D A;  3U5M A;  1LDK C;  5EYA F;  2ECG A;  3MHH A;  2LGG A;  4ZUX U;  2PUY A;  2M6M A;  1X4I A;  2YQM A;  1G25 A;  2ECW A;  3GV4 A;  3V43 A;  2VNF A;  3ZPV 1;  4CCG X;  4FO9 A;  5KH7 A;  2QIZ A;  4UI9 B;  2MA5 A;  4A0C D;  1VYX A;  1JM7 A;  2IDA A;  5H1U A;  3VK6 A;  3EB5 A;  1WE9 A;  2ECJ A;  3N9L A;  4N3W A;  2YHN A; 
#chains in the Genus database with same CATH topology
 2YUC A;  5B78 A;  1HYI A;  5LKU A;  3HTK C;  4P5O B;  3RPG B;  5TDR A;  3KV6 A;  2JRJ A;  3KDE C;  2M85 A;  2KE1 A;  2LGV A;  3O70 A;  2YUR A;  1V87 A;  2YSJ A;  3Q1D A;  1WEM A;  5AIT A;  1MM3 A;  4GB0 A;  1N87 A;  5H1V A;  3ASL A;  3GL6 A;  1WEP A;  5DIN A;  3LVR E;  3KNV A;  2ECT A;  2VPE A;  2FSA A;  5FEY A;  2MNY A;  3U5N A;  2LRI C;  3O33 A;  4OGC A;  5AIU A;  2JMJ A;  4UP5 A;  1WEW A;  2KWN A;  2XB1 A;  2M3H A;  5C13 A;  3LRQ A;  2XOC A;  3PUR A;  2NAA A;  3LQI A;  2VPG A;  2Y43 A;  5C11 A;  2L80 A;  2E6R A;  2QJ0 A;  4AYC A;  4R2Y A;  4UP0 A;  5H9M A;  5I3L A;  1BOR A;  2CRW A;  3O7A A;  3EB6 A;  1WIM A;  2ECI A;  3ZYQ A;  4YAX A;  2DSM A;  2MD7 B;  3N9Q A;  1WEU A;  2KWK A;  2CT2 A;  4GNG A;  3ZTG A;  2YVR A;  3DDT A;  1VD4 A;  2B0O E;  3QZV A;  2YSM A;  3MHS A;  2FUI A;  3SOX A;  4L58 A;  1ZBD B;  2VJF A;  3HCS A;  3FAN A;  5B75 A;  5B77 A;  4GNE A;  2CSZ A;  2EOD A;  4I7C A;  5B79 A;  3M63 A;  5TBN A;  3T9K A;  1Z60 A;  3DWD A;  2YU4 A;  4AYC B;  3ZNI A;  3L1X A;  2C2V S;  4IC2 A;  4WA6 A;  5LKX A;  1T1H A;  2XP0 A;  2D8S A;  1E4U A;  1RMD A;  2YYR A;  5SVI A;  2KR4 A;  2EGM A;  4GNF A;  4IC3 A;  4MVT A;  2AN6 A;  4FK5 A;  3LJU X;  3I2D A;  1Z2Q A;  1X4J A;  2LXH C;  2L7P A;  5TRB A;  2JMI A;  2LV9 A;  2CKL A;  2FFW A;  2HYE D;  3N9M A;  5LKZ A;  2FUU A;  2RR4 A;  3N9P A;  5TDW A;  4A4B A;  2G45 A;  2G43 A;  3T7L A;  2M13 A;  4TKP B;  1JOC A;  5B8D A;  4LAD B;  2KIZ A;  4AUQ B;  3C5K A;  3PHD A;  2L0B A;  4F1P A;  2E61 A;  2VJF B;  5H1T A;  3ZVZ B;  1WEE A;  2JMD A;  4QF3 A;  1X4U A;  2MT5 A;  3U5P A;  1WES A;  3SOW A;  3O47 A;  3SOU A;  2VJE A;  1LDJ B;  4XI1 A;  2YT5 A;  5SVI B;  5KH3 A;  4N4F A;  2MUM A;  4O64 A;  2LN0 A;  2KGG A;  4R8P K;  3FAO A;  3FM8 C;  2MD8 C;  3T6R A;  1F62 A;  4QQ4 A;  5KH9 A;  2ECV A;  4LJN A;  1DVP A;  3PLW A;  3RTR B;  2CSV A;  2XEU A;  2M1R A;  4R7E A;  2PNX A;  2XOY A;  3H7H A;  1WEO A;  5K3Q A;  2CKL B;  2MNZ A;  2DX8 A;  3FL2 A;  2CON A;  1U6G B;  2JM3 A;  2KFT A;  2ECN A;  2G6Q A;  2EGP A;  4S3O C;  1HYJ A;  4FIP A;  4X3G A;  3O34 A;  3M62 A;  2Y1N A;  2I50 A;  4H9D A;  2LDR A;  4Z0R A;  4A4C A;  3ZVY A;  2KYU A;  2RSD A;  2VJE B;  1WEQ A;  1IYM A;  3N9N A;  2L75 A;  1MBM A;  2ZET C;  3KQI A;  5D1L B;  3KV5 A;  2KKX A;  1K2F A;  2Y1M A;  5LKT A;  5D1K B;  1FBV A;  5DKA A;  4B7Y C;  2LGK A;  2MA6 A;  4V3L C;  3LVQ E;  2OXQ C;  3MDB C;  2XOZ A;  4YAT A;  2L43 A;  2F6N A;  1WGM A;  5G04 B;  5TAB A;  2LGL A;  3ZPV E;  2KWO A;  5FB1 A;  4YC9 A;  3NG2 A;  2YW8 A;  2YQL A;  5FB0 A;  2E6S A;  3O35 A;  3L11 A;  4L7X A;  4BHW A;  4WZ0 A;  2K1J A;  2K17 A;  2RI7 A;  2LQ6 A;  2QIC A;  2H0D A;  4YBT A;  3LDY A;  2KU3 A;  2LAU A;  2K16 A;  3DPL R;  4BBQ A;  5SVY A;  5B76 A;  4WZ3 B;  3M99 A;  2KGI A;  4NN2 A;  3FJU B;  4AVX A;  4O62 A;  3LQH A;  4LLB A;  4A49 A;  4C9Z A;  4F52 B;  4YBS A;  2YHO A;  2F42 A;  4LK9 A;  4W4U A;  4B86 C;  5FER A;  1WEV A;  4S3O B;  4AP4 A;  2KWJ A;  2BAY A;  2CSY A;  4ZDT A;  2DJA A;  3O37 A;  1WFK A;  3C6W A;  3U5O A;  4PPE A;  4CA1 A;  2D8U A;  4I7B A;  2VP7 A;  3FEH A;  3HCT A;  1Z6U A;  1DCQ A;  1XWH A;  3LQJ A;  4I7D A;  4YAD A;  4Q6F A;  3PUQ A;  4ZQL A;  3HCU A;  5G0F A;  2MKE A;  5LCW B;  2H0D B;  2HDP A;  4PTB A;  1JM7 B;  4MSX A;  5J3X A;  3E2D A;  2UZG A;  2MIQ A;  1WEN A;  2KRE A;  2C2L A;  3DQV R;  5G05 B;  2F6J A;  3L1Z B;  5D1M B;  2P57 A;  4GND A;  2YRE A;  5SVX A;  4V3K C;  4YAB A;  3RPG C;  2IQJ A;  4QF2 A;  3N9O A;  2VPB A;  4LKA A;  4FJC A;  4YBM A;  4Z0O A;  3M7K A;  2LXP C;  2L5U A;  3SHB A;  2VPD A;  4WZ2 A;  1FP0 A;  2EXU A;  2CRR A;  2EA6 A;  5JG6 A;  1MM2 A;  3O36 A;  2OWA A;  1VFY A;  1WIL A;  3JUE A;  1CHC A;  3IHP A;  2K4D A;  3U5M A;  1LDK C;  5EYA F;  2ECG A;  3MHH A;  2LGG A;  4ZUX U;  2KKY A;  2PUY A;  2M6M A;  1X4I A;  2YQM A;  1G25 A;  2ECW A;  3GV4 A;  3V43 A;  4OGE A;  2VNF A;  3ZPV 1;  4CCG X;  4FO9 A;  5KH7 A;  2QIZ A;  4UI9 B;  2MA5 A;  2FD4 A;  4A0C D;  1VYX A;  1JM7 A;  3SUB A;  2IDA A;  5H1U A;  3VK6 A;  2JUN A;  3EB5 A;  1WE9 A;  2ECJ A;  3N9L A;  4N3W A;  2YHN A; 
#chains in the Genus database with same CATH homology
 2YUC A;  5B78 A;  1HYI A;  5LKU A;  3HTK C;  4P5O B;  3RPG B;  5TDR A;  3KV6 A;  2JRJ A;  2M85 A;  2KE1 A;  2LGV A;  3O70 A;  2YUR A;  1V87 A;  2YSJ A;  1WEM A;  5AIT A;  1MM3 A;  4GB0 A;  1N87 A;  5H1V A;  3ASL A;  3GL6 A;  1WEP A;  5DIN A;  3KNV A;  2ECT A;  2VPE A;  2FSA A;  5FEY A;  2MNY A;  3U5N A;  2LRI C;  3O33 A;  5AIU A;  2JMJ A;  4UP5 A;  1WEW A;  2KWN A;  2XB1 A;  2M3H A;  5C13 A;  3LRQ A;  3PUR A;  2NAA A;  2Y43 A;  2VPG A;  3LQI A;  5C11 A;  2L80 A;  2E6R A;  2QJ0 A;  4AYC A;  4R2Y A;  4UP0 A;  5H9M A;  5I3L A;  1BOR A;  3O7A A;  3EB6 A;  1WIM A;  2ECI A;  3ZYQ A;  4YAX A;  2MD7 B;  3N9Q A;  1WEU A;  2KWK A;  2CT2 A;  4GNG A;  3ZTG A;  1VD4 A;  3QZV A;  2YSM A;  3MHS A;  2FUI A;  3SOX A;  4L58 A;  1ZBD B;  2VJF A;  3HCS A;  5B77 A;  5B75 A;  4GNE A;  2CSZ A;  2EOD A;  4I7C A;  5B79 A;  3M63 A;  5TBN A;  1Z60 A;  2YU4 A;  4AYC B;  3ZNI A;  3L1X A;  2C2V S;  4IC2 A;  4WA6 A;  5LKX A;  1T1H A;  2D8S A;  1E4U A;  1RMD A;  2YYR A;  2KR4 A;  4GNF A;  4IC3 A;  4MVT A;  2AN6 A;  4FK5 A;  3I2D A;  1Z2Q A;  1X4J A;  2LXH C;  5TRB A;  2JMI A;  2LV9 A;  2CKL A;  2HYE D;  3N9M A;  5LKZ A;  2FUU A;  3N9P A;  5TDW A;  4A4B A;  2G45 A;  2G43 A;  3T7L A;  4TKP B;  5B8D A;  1JOC A;  4LAD B;  2KIZ A;  4AUQ B;  3C5K A;  3PHD A;  2L0B A;  2VJF B;  5H1T A;  3ZVZ B;  1WEE A;  2JMD A;  4QF3 A;  1X4U A;  2MT5 A;  3U5P A;  1WES A;  3SOW A;  3SOU A;  2VJE A;  1LDJ B;  4XI1 A;  2YT5 A;  5KH3 A;  4N4F A;  2MUM A;  4O64 A;  2LN0 A;  2KGG A;  4R8P K;  2MD8 C;  3T6R A;  1F62 A;  5KH9 A;  2ECV A;  4LJN A;  1DVP A;  3RTR B;  2XEU A;  2M1R A;  2PNX A;  4R7E A;  1WEO A;  2CKL B;  2MNZ A;  2DX8 A;  3FL2 A;  1U6G B;  2KFT A;  2ECN A;  2G6Q A;  2EGP A;  4S3O C;  1HYJ A;  4FIP A;  4X3G A;  3O34 A;  3M62 A;  2Y1N A;  2I50 A;  2LDR A;  4A4C A;  3ZVY A;  2KYU A;  2RSD A;  2VJE B;  1WEQ A;  1IYM A;  3N9N A;  2L75 A;  2ZET C;  3KQI A;  5D1L B;  3KV5 A;  1K2F A;  2Y1M A;  5LKT A;  5D1K B;  1FBV A;  5DKA A;  4B7Y C;  2LGK A;  2MA6 A;  4V3L C;  2OXQ C;  4YAT A;  2L43 A;  2F6N A;  1WGM A;  5G04 B;  5TAB A;  2LGL A;  3ZPV E;  2KWO A;  5FB1 A;  4YC9 A;  3NG2 A;  2YW8 A;  2YQL A;  5FB0 A;  2E6S A;  3O35 A;  3L11 A;  4L7X A;  4BHW A;  4WZ0 A;  2K1J A;  2K17 A;  2RI7 A;  2LQ6 A;  2QIC A;  2H0D A;  4YBT A;  2KU3 A;  2K16 A;  3DPL R;  4BBQ A;  5B76 A;  4WZ3 B;  3M99 A;  2KGI A;  4NN2 A;  4AVX A;  3LQH A;  4LLB A;  4A49 A;  4C9Z A;  4F52 B;  4YBS A;  2YHO A;  2F42 A;  4LK9 A;  4W4U A;  4B86 C;  5FER A;  1WEV A;  4S3O B;  4AP4 A;  2KWJ A;  2BAY A;  2CSY A;  4ZDT A;  3O37 A;  1WFK A;  3C6W A;  3U5O A;  4PPE A;  4CA1 A;  4I7B A;  2VP7 A;  3HCT A;  1Z6U A;  1XWH A;  3LQJ A;  4I7D A;  5G0F A;  4Q6F A;  3PUQ A;  4YAD A;  3HCU A;  5LCW B;  4ZQL A;  1JM7 B;  2H0D B;  2HDP A;  4PTB A;  4MSX A;  5J3X A;  2UZG A;  2MIQ A;  1WEN A;  2KRE A;  2C2L A;  3DQV R;  5G05 B;  2F6J A;  3L1Z B;  5D1M B;  4GND A;  2YRE A;  4V3K C;  4YAB A;  3RPG C;  4QF2 A;  3N9O A;  2VPB A;  4LKA A;  4FJC A;  4YBM A;  2LXP C;  2L5U A;  3SHB A;  2VPD A;  4WZ2 A;  1FP0 A;  2EA6 A;  5JG6 A;  1MM2 A;  3O36 A;  1VFY A;  1WIL A;  1CHC A;  3IHP A;  2K4D A;  3U5M A;  1LDK C;  5EYA F;  2ECG A;  3MHH A;  2LGG A;  4ZUX U;  2PUY A;  2M6M A;  1X4I A;  2YQM A;  1G25 A;  2ECW A;  3GV4 A;  3V43 A;  2VNF A;  3ZPV 1;  4CCG X;  4FO9 A;  5KH7 A;  2QIZ A;  4UI9 B;  2MA5 A;  4A0C D;  1VYX A;  1JM7 A;  2IDA A;  5H1U A;  3VK6 A;  3EB5 A;  1WE9 A;  2ECJ A;  3N9L A;  4N3W A;  2YHN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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