2XOYA

C-terminal cysteine-rich domain of human chfr bound to p(1),p(2)- diadenosine-5'-pyrophosphate
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
239
structure length
212
Chain Sequence
PYVVCRQCPEYRRQAAQPPHCPDYVCPLQGSHALCTCCFQPMPDRRVEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYESDILKNYLATRGLTWKNMLTESLVALQRGVFLLSDYRVTGDTVLCYCCGLRSFRELTYQYRQNIPASELPVAVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of Poly(Adp-Ribose) Recognition by the Multizinc Binding Domain of Checkpoint with Forkhead-Associated and Ring Domains (Chfr).
pubmed doi rcsb
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE CHFR
molecule tags Ligase
source organism Homo sapiens
total genus 65
structure length 212
sequence length 239
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2010-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF10283 zf-CCHH PBZ domain
A PF17979 zf-CRD Cysteine rich domain with multizinc binding regions
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.140 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Herpes Virus-1 2xoyA01
2XOZA 2XP0A 2XOYA 2XOCA
chains in the Genus database with same CATH superfamily
2K17A 4LADB 2M6MA 4S3OC 1DCQA 3LQIA 5LKUA 3NG2A 4R8PK 4FJCA 3FANA 5C11A 3FL2A 4LLBA 5TBNA 2YSJA 4BHWA 2G45A 2OXQC 4LJNA 4ZQLA 5LCWB 2IQJA 1K2FA 2XB1A 3U5PA 1HYJA 2M3HA 1V87A 2C2VS 2YURA 1X4UA 1E4UA 4YABA 2JMDA 4A0CD 4BBQA 1HYIA 4A4CA 2QJ0A 3SHBA 3EB5A 4B86C 1WEMA 2MD7B 3LVRE 5KH3A 3M63A 4WA6A 4IC2A 2RSDA 3PUQA 3LQJA 5FB0A 1VYXA 5H1UA 4AP4A 3SOUA 2ECNA 3L1XA 1DVPA 3JUEA 2XOZA 1WE9A 4YBMA 4MSXA 2H0DB 4MVTA 4O64A 4YC9A 4R2YA 4QF3A 3E2DA 3U5MA 4IC3A 2YUCA 2CSYA 4AUQB 4R7EA 3N9NA 2G43A 1WEEA 1WIMA 3ZTGA 5I3LA 2MUMA 3M99A 3RTRB 3GL6A 2C2LA 2UZGA 1F62A 2VPBA 2EGPA 2LAUA 1T1HA 5B79A 3H7HA 2CONA 1WENA 5K3QA 1IYMA 3ZYQA 3O70A 3HCUA 4LKAA 2YU4A 3MDBC 2YYRA 1WEVA 1LDKC 2K4DA 2QIZA 4N3WA 2CSZA 3FAOA 2KKYA 2LGLA 2E61A 5G04B 5TRBA 2EGMA 5DINA 4S3OB 2CRRA 2BAYA 2PNXA 2YREA 5SVXA 2KKXA 3MHSA 2Y1NA 2KU3A 1MM3A 5LKZA 4F52B 5D1KB 5SVIB 2FUIA 5FB1A 3I2DA 4Q6FA 2EXUA 4QF2A 3L11A 4AVXA 2MKEA 1X4IA 4WZ0A 4V3KC 2LV9A 4YBTA 2L43A 4UP0A 3KNVA 4UI9B 1VD4A 2VP7A 4N4FA 2XOCA 5B77A 3IHPA 2H0DA 2MA5A 3MHHA 4AYCB 2DX8A 3ZVZB 2L75A 2KGIA 3SUBA 3U5OA 2HDPA 2L5UA 3L1ZB 3V43A 4I7CA 3U5NA 2KGGA 1WEWA 2YVRA 2Y43A 3FM8C 1FP0A 3RPGC 4UP5A 1Z2QA 4I7DA 5LKTA 1WEOA 5J3XA 3O35A 3M62A 1U6GB 2VJFB 2KWNA 4CCGX 4GNEA 2YQMA 2LGGA 3KV6A 3O37A 2KIZA 5B78A 2FSAA 1LDJB 2M85A 2D8UA 2OWAA 3ZPVE 2ECVA 4LK9A 1WGMA 4YADA 3N9QA 4TKPB 3HTKC 3M7KA 2LGVA 2PUYA 4H9DA 2DJAA 2G6QA 2MNZA 2E6RA 4ZUXU 5G0FA 3QZVA 1WESA 2IDAA 4I7BA 5H9MA 5G05B 2LXPC 2EA6A 3ZPV1 3O47A 2F6NA 3DWDA 2RI7A 3FEHA 2F6JA 1XWHA 2MNYA 2VNFA 4Z0OA 4OGEA 4A49A 5KH9A 2Y1MA 3GV4A 5H1TA 2D8SA 5B75A 5SVIA 2VPEA 2M13A 3O33A 1FBVA 2KREA 4YBSA 3Q1DA 1WFKA 2RR4A 3HCSA 4O62A 2KYUA 2LXHC 3ZNIA 4FO9A 3C5KA 4L7XA 4AYCA 2YW8A 2ZETC 2ECJA 2HYED 2KE1A 1N87A 2I50A 2EODA 3EB6A 2CSVA 4B7YC 2CKLA 3PLWA 3KV5A 2MIQA 3T9KA 5LKXA 1CHCA 1X4JA 2LQ6A 2VJFA 3O36A 2JMIA 3T7LA 2K16A 2MD8C 4GNDA 2YHOA 4L58A 1WILA 3N9MA 4V3LC 2DSMA 2B0OE 2NAAA 4QQ4A 5D1MB 2YHNA 1JM7A 2E6SA 1MBMA 3RPGB 3HCTA 4GNFA 2XEUA 3LQHA 3ZVYA 4P5OB 3N9LA 1ZBDB 2ECWA 2LRIC 4FK5A 2JM3A 4YATA 2CKLB 2CT2A 2ECTA 5SVYA 2KR4A 3T6RA 5B76A 3KQIA 3SOWA 4WZ3B 1G25A 3LDYA 3ASLA 2KFTA 3N9OA 4Z0RA 2L7PA 1JM7B 3DQVR 2FUUA 4ZDTA 2VPGA 3N9PA 2K1JA 2VJEA 3DPLR 2XP0A 2YT5A 3LVQE 1VFYA 3KDEC 5TDWA 3VK6A 5TABA 1WEPA 5EYAF 2L0BA 3DDTA 1RMDA 2JRJA 5B8DA 1Z6UA 2JUNA 4YAXA 1MM2A 2ECIA 2QICA 4NN2A 5FERA 1Z60A 2YQLA 4A4BA 3LRQA 2VPDA 3O34A 2LN0A 1WEQA 3C6WA 5AIUA 2LGKA 2MA6A 5C13A 2XOYA 2KWKA 2LDRA 2CRWA 5H1VA 2VJEB 4W4UA 2MT5A 2P57A 4FIPA 2YSMA 3O7AA 1WEUA 4OGCA 4X3GA 2ECGA 2FD4A 5JG6A 4GB0A 4CA1A 5D1LB 2L80A 3LJUX 5KH7A 2AN6A 5AITA 3SOXA 4F1PA 4XI1A 2KWOA 2KWJA 3PURA 2F42A 3PHDA 5FEYA 4PPEA 5DKAA 3FJUB 1JOCA 4PTBA 2FFWA 4WZ2A 4C9ZA 5TDRA 1BORA 2JMJA 4GNGA 2M1RA
chains in the Genus database with same CATH topology
2B0OE 5SVIA 2M13A 3KDEC 4QQ4A 2XOYA 3MDBC 2CRWA 4F1PA 2CSVA 3DDTA 1DCQA 3SUBA 3JUEA 3Q1DA 2RR4A 2XOZA 3LDYA 3PLWA 4O62A 2P57A 2D8UA 3O47A 5SVIB 3DWDA 2OWAA 3FEHA 2EXUA 3T9KA 2JUNA 2KKYA 2MKEA 2YVRA 2E61A 4Z0OA 3E2DA 3FM8C 2L7PA 4OGEA 4Z0RA 4OGCA 3FJUB 2JM3A 3M7KA 2EGMA 2FFWA 2LAUA 3LVRE 2CRRA 2FD4A 5K3QA 2YREA 3H7HA 5SVYA 2CONA 2IQJA 4H9DA 2XP0A 5SVXA 2DJAA 3LJUX 3LVQE 2KKXA 2XOCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XOZ A;  2XP0 A;  2XOY A;  2XOC A; 
#chains in the Genus database with same CATH topology
 2K17 A;  4LAD B;  2M6M A;  4S3O C;  1DCQ A;  3LQI A;  5LKU A;  3NG2 A;  4R8P K;  4FJC A;  3FAN A;  5C11 A;  3FL2 A;  4LLB A;  5TBN A;  2YSJ A;  4BHW A;  2G45 A;  2OXQ C;  4LJN A;  4ZQL A;  5LCW B;  2IQJ A;  1K2F A;  2XB1 A;  3U5P A;  1HYJ A;  2M3H A;  1V87 A;  2C2V S;  2YUR A;  1X4U A;  1E4U A;  4YAB A;  2JMD A;  4A0C D;  4BBQ A;  1HYI A;  4A4C A;  2QJ0 A;  3SHB A;  3EB5 A;  4B86 C;  1WEM A;  2MD7 B;  3LVR E;  5KH3 A;  3M63 A;  4WA6 A;  4IC2 A;  2RSD A;  3PUQ A;  3LQJ A;  5FB0 A;  1VYX A;  5H1U A;  4AP4 A;  3SOU A;  2ECN A;  3L1X A;  1DVP A;  3JUE A;  2XOZ A;  1WE9 A;  4YBM A;  4MSX A;  2H0D B;  4MVT A;  4O64 A;  4YC9 A;  4R2Y A;  4QF3 A;  3E2D A;  3U5M A;  4IC3 A;  2YUC A;  2CSY A;  4AUQ B;  4R7E A;  3N9N A;  2G43 A;  1WEE A;  1WIM A;  3ZTG A;  5I3L A;  2MUM A;  3M99 A;  3RTR B;  3GL6 A;  2C2L A;  2UZG A;  1F62 A;  2VPB A;  2EGP A;  2LAU A;  1T1H A;  5B79 A;  3H7H A;  2CON A;  1WEN A;  5K3Q A;  1IYM A;  3ZYQ A;  3O70 A;  3HCU A;  4LKA A;  2YU4 A;  3MDB C;  2YYR A;  1WEV A;  1LDK C;  2K4D A;  2QIZ A;  4N3W A;  2CSZ A;  3FAO A;  2KKY A;  2LGL A;  2E61 A;  5G04 B;  5TRB A;  2EGM A;  5DIN A;  4S3O B;  2CRR A;  2BAY A;  2PNX A;  2YRE A;  5SVX A;  2KKX A;  3MHS A;  2Y1N A;  2KU3 A;  1MM3 A;  5LKZ A;  4F52 B;  5D1K B;  5SVI B;  2FUI A;  5FB1 A;  3I2D A;  4Q6F A;  2EXU A;  4QF2 A;  3L11 A;  4AVX A;  2MKE A;  1X4I A;  4WZ0 A;  4V3K C;  2LV9 A;  4YBT A;  2L43 A;  4UP0 A;  3KNV A;  4UI9 B;  1VD4 A;  2VP7 A;  4N4F A;  2XOC A;  5B77 A;  3IHP A;  2H0D A;  2MA5 A;  3MHH A;  4AYC B;  2DX8 A;  3ZVZ B;  2L75 A;  2KGI A;  3SUB A;  3U5O A;  2HDP A;  2L5U A;  3L1Z B;  3V43 A;  4I7C A;  3U5N A;  2KGG A;  1WEW A;  2YVR A;  2Y43 A;  3FM8 C;  1FP0 A;  3RPG C;  4UP5 A;  1Z2Q A;  4I7D A;  5LKT A;  1WEO A;  5J3X A;  3O35 A;  3M62 A;  1U6G B;  2VJF B;  2KWN A;  4CCG X;  4GNE A;  2YQM A;  2LGG A;  3KV6 A;  3O37 A;  2KIZ A;  5B78 A;  2FSA A;  1LDJ B;  2M85 A;  2D8U A;  2OWA A;  3ZPV E;  2ECV A;  4LK9 A;  1WGM A;  4YAD A;  3N9Q A;  4TKP B;  3HTK C;  3M7K A;  2LGV A;  2PUY A;  4H9D A;  2DJA A;  2G6Q A;  2MNZ A;  2E6R A;  4ZUX U;  5G0F A;  3QZV A;  1WES A;  2IDA A;  4I7B A;  5H9M A;  5G05 B;  2LXP C;  2EA6 A;  3ZPV 1;  3O47 A;  2F6N A;  3DWD A;  2RI7 A;  3FEH A;  2F6J A;  1XWH A;  2MNY A;  2VNF A;  4Z0O A;  4OGE A;  4A49 A;  5KH9 A;  2Y1M A;  3GV4 A;  5H1T A;  2D8S A;  5B75 A;  5SVI A;  2VPE A;  2M13 A;  3O33 A;  1FBV A;  2KRE A;  4YBS A;  3Q1D A;  1WFK A;  2RR4 A;  3HCS A;  4O62 A;  2KYU A;  2LXH C;  3ZNI A;  4FO9 A;  3C5K A;  4L7X A;  4AYC A;  2YW8 A;  2ZET C;  2ECJ A;  2HYE D;  2KE1 A;  1N87 A;  2I50 A;  2EOD A;  3EB6 A;  2CSV A;  4B7Y C;  2CKL A;  3PLW A;  3KV5 A;  2MIQ A;  3T9K A;  5LKX A;  1CHC A;  1X4J A;  2LQ6 A;  2VJF A;  3O36 A;  2JMI A;  3T7L A;  2K16 A;  2MD8 C;  4GND A;  2YHO A;  4L58 A;  1WIL A;  3N9M A;  4V3L C;  2DSM A;  2B0O E;  2NAA A;  4QQ4 A;  5D1M B;  2YHN A;  1JM7 A;  2E6S A;  1MBM A;  3RPG B;  3HCT A;  4GNF A;  2XEU A;  3LQH A;  3ZVY A;  4P5O B;  3N9L A;  1ZBD B;  2ECW A;  2LRI C;  4FK5 A;  2JM3 A;  4YAT A;  2CKL B;  2CT2 A;  2ECT A;  5SVY A;  2KR4 A;  3T6R A;  5B76 A;  3KQI A;  3SOW A;  4WZ3 B;  1G25 A;  3LDY A;  3ASL A;  2KFT A;  3N9O A;  4Z0R A;  2L7P A;  1JM7 B;  3DQV R;  2FUU A;  4ZDT A;  2VPG A;  3N9P A;  2K1J A;  2VJE A;  3DPL R;  2XP0 A;  2YT5 A;  3LVQ E;  1VFY A;  3KDE C;  5TDW A;  3VK6 A;  5TAB A;  1WEP A;  5EYA F;  2L0B A;  3DDT A;  1RMD A;  2JRJ A;  5B8D A;  1Z6U A;  2JUN A;  4YAX A;  1MM2 A;  2ECI A;  2QIC A;  4NN2 A;  5FER A;  1Z60 A;  2YQL A;  4A4B A;  3LRQ A;  2VPD A;  3O34 A;  2LN0 A;  1WEQ A;  3C6W A;  5AIU A;  2LGK A;  2MA6 A;  5C13 A;  2XOY A;  2KWK A;  2LDR A;  2CRW A;  5H1V A;  2VJE B;  4W4U A;  2MT5 A;  2P57 A;  4FIP A;  2YSM A;  3O7A A;  1WEU A;  4OGC A;  4X3G A;  2ECG A;  2FD4 A;  5JG6 A;  4GB0 A;  4CA1 A;  5D1L B;  2L80 A;  3LJU X;  5KH7 A;  2AN6 A;  5AIT A;  3SOX A;  4F1P A;  4XI1 A;  2KWO A;  2KWJ A;  3PUR A;  2F42 A;  3PHD A;  5FEY A;  4PPE A;  5DKA A;  3FJU B;  1JOC A;  4PTB A;  2FFW A;  4WZ2 A;  4C9Z A;  5TDR A;  1BOR A;  2JMJ A;  4GNG A;  2M1R A; 
#chains in the Genus database with same CATH homology
 2B0O E;  5SVI A;  2M13 A;  3KDE C;  4QQ4 A;  2XOY A;  3MDB C;  2CRW A;  4F1P A;  2CSV A;  3DDT A;  1DCQ A;  3SUB A;  3JUE A;  3Q1D A;  2RR4 A;  2XOZ A;  3LDY A;  3PLW A;  4O62 A;  2P57 A;  2D8U A;  3O47 A;  5SVI B;  3DWD A;  2OWA A;  3FEH A;  2EXU A;  3T9K A;  2JUN A;  2KKY A;  2MKE A;  2YVR A;  2E61 A;  4Z0O A;  3E2D A;  3FM8 C;  2L7P A;  4OGE A;  4Z0R A;  4OGC A;  3FJU B;  2JM3 A;  3M7K A;  2EGM A;  2FFW A;  2LAU A;  3LVR E;  2CRR A;  2FD4 A;  5K3Q A;  2YRE A;  3H7H A;  5SVY A;  2CON A;  2IQJ A;  4H9D A;  2XP0 A;  5SVX A;  2DJA A;  3LJU X;  3LVQ E;  2KKX A;  2XOC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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