3KDEC

Crystal structure of the thap domain from d. melanogaster p-element transposase in complex with its natural dna binding site
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
76
structure length
74
Chain Sequence
MKYCKFCCKAVTGVKLIHVPKCAIKRKLWEQSLGCSLGENSQICDTHFNDSQWKAAKGQTFKRRRLNADAVPSK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 5'-D(*GP*TP*TP*AP*AP*GP*(BRU)P*GP*GP*A)-3'
publication title THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves.
pubmed doi rcsb
source organism Drosophila melanogaster
molecule tags Dna binding protein/dna
total genus 13
structure length 74
sequence length 76
ec nomenclature
pdb deposition date 2009-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF05485 THAP THAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.180 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Herpes Virus-1 3kdeC01
2JM3A 3KDEC 2LAUA
chains in the Genus database with same CATH superfamily
5LKUA 3KV5A 1ZBDB 2MUMA 4WZ0A 3FL2A 1VFYA 3IHPA 2L80A 2KGGA 4ZUXU 1FBVA 2MIQA 1XWHA 2YQLA 4FK5A 3ZVYA 3M99A 3LQHA 4AVXA 1WEWA 3SOWA 5H9MA 4C9ZA 4UI9B 3SOUA 1X4JA 2M13A 1WEQA 4LKAA 4NN2A 2CKLB 2EA6A 5DKAA 2VNFA 4X3GA 2XOYA 1JOCA 1Z6UA 5SVYA 3ZPVE 4A0CD 3EB6A 2KREA 2LV9A 5TBNA 4PTBA 3EB5A 5D1MB 4A4BA 3O35A 4V3KC 1G25A 3QZVA 2LN0A 2YURA 2L7PA 4QQ4A 3DQVR 1FP0A 4I7CA 4YABA 2VJEB 1DVPA 2LGGA 4FIPA 2M85A 4I7BA 3ZTGA 5SVXA 4UP0A 2ECWA 5B79A 3I2DA 2KWNA 2KKYA 3DDTA 5EYAF 4PPEA 3T7LA 2FD4A 4B7YC 1F62A 2G45A 4CA1A 3Q1DA 2QICA 1T1HA 2YU4A 3O37A 2IDAA 2BAYA 2NAAA 2AN6A 2RR4A 3ZVZB 5SVIB 2XP0A 2OXQC 2CRRA 4O62A 2ECJA 2RI7A 1WENA 4ZQLA 3SHBA 5DINA 5B8DA 5FERA 5KH9A 5H1VA 1Z2QA 2LQ6A 1WE9A 5B77A 5I3LA 4R2YA 1WILA 2YSJA 3N9PA 3T6RA 4WZ3B 2CSZA 2EGPA 4MVTA 2PNXA 2YYRA 3N9NA 2VJFA 3ASLA 2MKEA 2L5UA 3O70A 3FAOA 2ECVA 1MM3A 3KNVA 5G05B 2KE1A 2C2VS 1X4IA 1N87A 4LADB 1CHCA 2FUIA 1WEUA 1WEOA 2M6MA 3T9KA 1JM7A 3N9OA 5FEYA 2JMJA 1WEPA 5G04B 3HTKC 4OGCA 3C6WA 5KH7A 3RPGB 2EXUA 2CONA 1E4UA 4S3OB 3M62A 3U5MA 2XB1A 1WIMA 2EGMA 2MNYA 1V87A 3GV4A 3O36A 5KH3A 3N9QA 2VPDA 2JUNA 3PLWA 2CRWA 3ZYQA 3GL6A 2KIZA 2MA5A 4N4FA 2M3HA 4QF2A 2G6QA 3PUQA 2H0DA 2KWOA 2VPEA 2JRJA 2MNZA 5C11A 2FFWA 3L1ZB 2E6SA 2VP7A 5B76A 2JMIA 4R8PK 5G0FA 1VYXA 5H1UA 2QJ0A 4N3WA 5K3QA 4XI1A 4BHWA 3RPGC 5B75A 4S3OC 2G43A 3ZNIA 4Z0RA 1WESA 4WZ2A 5D1LB 2K4DA 2UZGA 4Q6FA 2KKXA 5D1KB 3LDYA 2Y1MA 5AIUA 1WEMA 3O33A 2KGIA 2L75A 2LGVA 2B0OE 1U6GB 2F6NA 5H1TA 2CSVA 2ECIA 4YC9A 4I7DA 1RMDA 1WGMA 3KV6A 4LK9A 5AITA 3U5NA 1MBMA 4GNEA 2CKLA 2D8SA 5LKXA 4O64A 2E6RA 1Z60A 4LJNA 2D8UA 4GNGA 4YBTA 5J3XA 4IC3A 2ECGA 2LDRA 2Y1NA 5C13A 3LJUX 3N9MA 5FB0A 4YBMA 2LGLA 4A4CA 2FUUA 3MHHA 4FO9A 3HCUA 3M7KA 4TKPB 2KWJA 2VJEA 4GNFA 4FJCA 2K17A 2XOZA 4Z0OA 4YAXA 5JG6A 2YT5A 5TDWA 3FM8C 3LVQE 1VD4A 1BORA 2YW8A 5FB1A 4YBSA 2HDPA 5TDRA 4QF3A 3O34A 4OGEA 1WEEA 5SVIA 1DCQA 2LXHC 5LKZA 1WEVA 2LAUA 3LQJA 2F6JA 2MD8C 1MM2A 2VPBA 4IC2A 5TRBA 2HYED 4F1PA 4AP4A 3KDEC 4AYCB 4AUQB 1WFKA 2YVRA 3FANA 2K1JA 2MT5A 3PURA 4GB0A 2FSAA 2F42A 2DSMA 2ZETC 4W4UA 3H7HA 2I50A 2Y43A 1HYIA 2RSDA 3U5OA 2C2LA 5LKTA 4R7EA 3MHSA 4L58A 3VK6A 2QIZA 2XOCA 3PHDA 3SOXA 2LGKA 2DJAA 4YADA 1LDKC 4GNDA 2E61A 3ZPV1 4P5OB 3U5PA 4V3LC 3O47A 3C5KA 4UP5A 3DPLR 3O7AA 2VJFB 3JUEA 2KR4A 4F52B 5LCWB 2YUCA 4MSXA 1X4UA 3LVRE 2ECNA 3MDBC 2KWKA 4A49A 2LRIC 2VPGA 3HCSA 2L0BA 3FEHA 2YQMA 1JM7B 2OWAA 2JMDA 2ECTA 2XEUA 2EODA 3DWDA 2DX8A 3L1XA 2JM3A 2IQJA 1HYJA 4AYCA 2CT2A 3N9LA 4BBQA 2YHOA 2KFTA 2M1RA 2P57A 2KU3A 3RTRB 4LLBA 3HCTA 3LQIA 1K2FA 4WA6A 4H9DA 3KQIA 2MA6A 2L43A 2H0DB 2YHNA 3LRQA 2YREA 3E2DA 3FJUB 2PUYA 5TABA 3M63A 2CSYA 3V43A 1LDJB 3NG2A 2MD7B 2YSMA 4ZDTA 5B78A 3L11A 4CCGX 4L7XA 3SUBA 4B86C 2K16A 2KYUA 4YATA 2LXPC 1IYMA
chains in the Genus database with same CATH topology
2JM3A 2EGMA 2XOZA 3E2DA 3FJUB 2IQJA 2LAUA 3JUEA 4Z0OA 5SVIA 3H7HA 3PLWA 2JUNA 3LJUX 2B0OE 2CRWA 2XOYA 5SVXA 3FM8C 2RR4A 4Z0RA 5SVYA 2CSVA 3LVQE 5SVIB 2YREA 3T9KA 2XOCA 4F1PA 2P57A 2XP0A 2KKYA 3DDTA 3LVRE 3M7KA 2DJAA 3MDBC 3LDYA 3KDEC 2YVRA 2CRRA 2FFWA 2E61A 3O47A 4O62A 2MKEA 2FD4A 4OGCA 3SUBA 3FEHA 4H9DA 2EXUA 3Q1DA 2CONA 2OWAA 2L7PA 4OGEA 4QQ4A 5K3QA 2KKXA 2D8UA 2M13A 1DCQA 3DWDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JM3 A;  3KDE C;  2LAU A; 
#chains in the Genus database with same CATH topology
 5LKU A;  3KV5 A;  1ZBD B;  2MUM A;  4WZ0 A;  3FL2 A;  1VFY A;  3IHP A;  2L80 A;  2KGG A;  4ZUX U;  1FBV A;  2MIQ A;  1XWH A;  2YQL A;  4FK5 A;  3ZVY A;  3M99 A;  3LQH A;  4AVX A;  1WEW A;  3SOW A;  5H9M A;  4C9Z A;  4UI9 B;  3SOU A;  1X4J A;  2M13 A;  1WEQ A;  4LKA A;  4NN2 A;  2CKL B;  2EA6 A;  5DKA A;  2VNF A;  4X3G A;  2XOY A;  1JOC A;  1Z6U A;  5SVY A;  3ZPV E;  4A0C D;  3EB6 A;  2KRE A;  2LV9 A;  5TBN A;  4PTB A;  3EB5 A;  5D1M B;  4A4B A;  3O35 A;  4V3K C;  1G25 A;  3QZV A;  2LN0 A;  2YUR A;  2L7P A;  4QQ4 A;  3DQV R;  1FP0 A;  4I7C A;  4YAB A;  2VJE B;  1DVP A;  2LGG A;  4FIP A;  2M85 A;  4I7B A;  3ZTG A;  5SVX A;  4UP0 A;  2ECW A;  5B79 A;  3I2D A;  2KWN A;  2KKY A;  3DDT A;  5EYA F;  4PPE A;  3T7L A;  2FD4 A;  4B7Y C;  1F62 A;  2G45 A;  4CA1 A;  3Q1D A;  2QIC A;  1T1H A;  2YU4 A;  3O37 A;  2IDA A;  2BAY A;  2NAA A;  2AN6 A;  2RR4 A;  3ZVZ B;  5SVI B;  2XP0 A;  2OXQ C;  2CRR A;  4O62 A;  2ECJ A;  2RI7 A;  1WEN A;  4ZQL A;  3SHB A;  5DIN A;  5B8D A;  5FER A;  5KH9 A;  5H1V A;  1Z2Q A;  2LQ6 A;  1WE9 A;  5B77 A;  5I3L A;  4R2Y A;  1WIL A;  2YSJ A;  3N9P A;  3T6R A;  4WZ3 B;  2CSZ A;  2EGP A;  4MVT A;  2PNX A;  2YYR A;  3N9N A;  2VJF A;  3ASL A;  2MKE A;  2L5U A;  3O70 A;  3FAO A;  2ECV A;  1MM3 A;  3KNV A;  5G05 B;  2KE1 A;  2C2V S;  1X4I A;  1N87 A;  4LAD B;  1CHC A;  2FUI A;  1WEU A;  1WEO A;  2M6M A;  3T9K A;  1JM7 A;  3N9O A;  5FEY A;  2JMJ A;  1WEP A;  5G04 B;  3HTK C;  4OGC A;  3C6W A;  5KH7 A;  3RPG B;  2EXU A;  2CON A;  1E4U A;  4S3O B;  3M62 A;  3U5M A;  2XB1 A;  1WIM A;  2EGM A;  2MNY A;  1V87 A;  3GV4 A;  3O36 A;  5KH3 A;  3N9Q A;  2VPD A;  2JUN A;  3PLW A;  2CRW A;  3ZYQ A;  3GL6 A;  2KIZ A;  2MA5 A;  4N4F A;  2M3H A;  4QF2 A;  2G6Q A;  3PUQ A;  2H0D A;  2KWO A;  2VPE A;  2JRJ A;  2MNZ A;  5C11 A;  2FFW A;  3L1Z B;  2E6S A;  2VP7 A;  5B76 A;  2JMI A;  4R8P K;  5G0F A;  1VYX A;  5H1U A;  2QJ0 A;  4N3W A;  5K3Q A;  4XI1 A;  4BHW A;  3RPG C;  5B75 A;  4S3O C;  2G43 A;  3ZNI A;  4Z0R A;  1WES A;  4WZ2 A;  5D1L B;  2K4D A;  2UZG A;  4Q6F A;  2KKX A;  5D1K B;  3LDY A;  2Y1M A;  5AIU A;  1WEM A;  3O33 A;  2KGI A;  2L75 A;  2LGV A;  2B0O E;  1U6G B;  2F6N A;  5H1T A;  2CSV A;  2ECI A;  4YC9 A;  4I7D A;  1RMD A;  1WGM A;  3KV6 A;  4LK9 A;  5AIT A;  3U5N A;  1MBM A;  4GNE A;  2CKL A;  2D8S A;  5LKX A;  4O64 A;  2E6R A;  1Z60 A;  4LJN A;  2D8U A;  4GNG A;  4YBT A;  5J3X A;  4IC3 A;  2ECG A;  2LDR A;  2Y1N A;  5C13 A;  3LJU X;  3N9M A;  5FB0 A;  4YBM A;  2LGL A;  4A4C A;  2FUU A;  3MHH A;  4FO9 A;  3HCU A;  3M7K A;  4TKP B;  2KWJ A;  2VJE A;  4GNF A;  4FJC A;  2K17 A;  2XOZ A;  4Z0O A;  4YAX A;  5JG6 A;  2YT5 A;  5TDW A;  3FM8 C;  3LVQ E;  1VD4 A;  1BOR A;  2YW8 A;  5FB1 A;  4YBS A;  2HDP A;  5TDR A;  4QF3 A;  3O34 A;  4OGE A;  1WEE A;  5SVI A;  1DCQ A;  2LXH C;  5LKZ A;  1WEV A;  2LAU A;  3LQJ A;  2F6J A;  2MD8 C;  1MM2 A;  2VPB A;  4IC2 A;  5TRB A;  2HYE D;  4F1P A;  4AP4 A;  3KDE C;  4AYC B;  4AUQ B;  1WFK A;  2YVR A;  3FAN A;  2K1J A;  2MT5 A;  3PUR A;  4GB0 A;  2FSA A;  2F42 A;  2DSM A;  2ZET C;  4W4U A;  3H7H A;  2I50 A;  2Y43 A;  1HYI A;  2RSD A;  3U5O A;  2C2L A;  5LKT A;  4R7E A;  3MHS A;  4L58 A;  3VK6 A;  2QIZ A;  2XOC A;  3PHD A;  3SOX A;  2LGK A;  2DJA A;  4YAD A;  1LDK C;  4GND A;  2E61 A;  3ZPV 1;  4P5O B;  3U5P A;  4V3L C;  3O47 A;  3C5K A;  4UP5 A;  3DPL R;  3O7A A;  2VJF B;  3JUE A;  2KR4 A;  4F52 B;  5LCW B;  2YUC A;  4MSX A;  1X4U A;  3LVR E;  2ECN A;  3MDB C;  2KWK A;  4A49 A;  2LRI C;  2VPG A;  3HCS A;  2L0B A;  3FEH A;  2YQM A;  1JM7 B;  2OWA A;  2JMD A;  2ECT A;  2XEU A;  2EOD A;  3DWD A;  2DX8 A;  3L1X A;  2JM3 A;  2IQJ A;  1HYJ A;  4AYC A;  2CT2 A;  3N9L A;  4BBQ A;  2YHO A;  2KFT A;  2M1R A;  2P57 A;  2KU3 A;  3RTR B;  4LLB A;  3HCT A;  3LQI A;  1K2F A;  4WA6 A;  4H9D A;  3KQI A;  2MA6 A;  2L43 A;  2H0D B;  2YHN A;  3LRQ A;  2YRE A;  3E2D A;  3FJU B;  2PUY A;  5TAB A;  3M63 A;  2CSY A;  3V43 A;  1LDJ B;  3NG2 A;  2MD7 B;  2YSM A;  4ZDT A;  5B78 A;  3L11 A;  4CCG X;  4L7X A;  3SUB A;  4B86 C;  2K16 A;  2KYU A;  4YAT A;  2LXP C;  1IYM A; 
#chains in the Genus database with same CATH homology
 2JM3 A;  2EGM A;  2XOZ A;  3E2D A;  3FJU B;  2IQJ A;  2LAU A;  3JUE A;  4Z0O A;  5SVI A;  3H7H A;  3PLW A;  2JUN A;  3LJU X;  2B0O E;  2CRW A;  2XOY A;  5SVX A;  3FM8 C;  2RR4 A;  4Z0R A;  5SVY A;  2CSV A;  3LVQ E;  5SVI B;  2YRE A;  3T9K A;  2XOC A;  4F1P A;  2P57 A;  2XP0 A;  2KKY A;  3DDT A;  3LVR E;  3M7K A;  2DJA A;  3MDB C;  3LDY A;  3KDE C;  2YVR A;  2CRR A;  2FFW A;  2E61 A;  3O47 A;  4O62 A;  2MKE A;  2FD4 A;  4OGC A;  3SUB A;  3FEH A;  4H9D A;  2EXU A;  3Q1D A;  2CON A;  2OWA A;  2L7P A;  4OGE A;  4QQ4 A;  5K3Q A;  2KKX A;  2D8U A;  2M13 A;  1DCQ A;  3DWD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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