2XOYA

C-terminal cysteine-rich domain of human chfr bound to p(1),p(2)- diadenosine-5'-pyrophosphate
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
239
structure length
212
Chain Sequence
PYVVCRQCPEYRRQAAQPPHCPDYVCPLQGSHALCTCCFQPMPDRRVEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYESDILKNYLATRGLTWKNMLTESLVALQRGVFLLSDYRVTGDTVLCYCCGLRSFRELTYQYRQNIPASELPVAVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Ligase
source organism Homo sapiens
publication title Structural Basis of Poly(Adp-Ribose) Recognition by the Multizinc Binding Domain of Checkpoint with Forkhead-Associated and Ring Domains (Chfr).
pubmed doi rcsb
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE CHFR
total genus 65
structure length 212
sequence length 239
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2010-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF10283 zf-CCHH PBZ domain
A PF17979 zf-CRD Cysteine rich domain with multizinc binding regions
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.140 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Herpes Virus-1 2xoyA01
2XOYA 2XP0A 2XOZA 2XOCA
chains in the Genus database with same CATH superfamily
2VJEA 1XWHA 4W4UA 1LDKC 3ZPVE 4C9ZA 1HYIA 3E2DA 4V3LC 2VP7A 1WEOA 3LQJA 5TABA 2VJFA 4AP4A 3U5PA 2YQLA 2FD4A 1WEMA 3FANA 2FSAA 3EB5A 1WEUA 3L11A 2YQMA 4GNFA 1WGMA 1WILA 2EXUA 5JG6A 2L0BA 2PUYA 2RI7A 3O47A 4IC3A 2UZGA 2CSYA 5LKTA 5SVIA 3DWDA 4YADA 4QF3A 2MNZA 1HYJA 3T9KA 3T7LA 3LQIA 4PPEA 2VPBA 3GL6A 4Q6FA 2VPGA 3SOXA 3O37A 4OGEA 3ZPV1 2LN0A 4YAXA 4N4FA 5LCWB 1FP0A 1ZBDB 3PLWA 3O34A 1F62A 2CKLA 1WFKA 4S3OB 1V87A 4LJNA 2FFWA 2L75A 5AIUA 2YUCA 1K2FA 1DVPA 4XI1A 2YYRA 3LVRE 5G05B 2KKYA 3L1XA 4NN2A 2XP0A 3NG2A 4LKAA 2ECWA 2DX8A 4WA6A 2OXQC 3C6WA 3DPLR 1RMDA 2MKEA 2XEUA 3PHDA 4R7EA 5EYAF 2KGIA 2LGLA 2M6MA 3KV6A 3LJUX 4YC9A 2I50A 4P5OB 2CRWA 3KNVA 3HCTA 2KIZA 2YREA 1X4UA 4WZ3B 2K16A 2LRIC 5LKXA 4UI9B 5SVXA 2EODA 2E6RA 1VFYA 1MM2A 1WESA 2L43A 3FL2A 5B79A 3KV5A 3T6RA 3QZVA 5KH7A 2KWJA 4AUQB 1BORA 4YBSA 3I2DA 2K17A 2MIQA 1LDJB 2QJ0A 1WEVA 2XOYA 2G45A 2HYED 3V43A 2H0DB 4ZUXU 3KDEC 5B75A 2L80A 5D1MB 2MNYA 5G04B 5FERA 4H9DA 4BHWA 3MHSA 5DKAA 4S3OC 4PTBA 4UP5A 2AN6A 4YBTA 3C5KA 3LDYA 3EB6A 4MVTA 4AYCB 2M1RA 5FB0A 5I3LA 2LGKA 3O33A 4Z0OA 4F1PA 4V3KC 1MBMA 1JM7A 5H1VA 2G43A 2QICA 3N9OA 2XB1A 4I7DA 5K3QA 4B7YC 3M99A 4GNEA 2YU4A 2JMJA 3RPGB 2QIZA 4WZ0A 2G6QA 3O36A 2DSMA 2MT5A 4FK5A 3N9MA 4YBMA 2VPEA 2D8UA 1Z60A 2F6JA 2C2VS 3ZTGA 4X3GA 3N9NA 5H1TA 2ZETC 2LV9A 4LADB 2JMDA 4OGCA 1VD4A 3N9LA 3FAOA 2JM3A 1G25A 3MHHA 1T1HA 4FJCA 3O7AA 2P57A 3SHBA 2LQ6A 3ASLA 3HCUA 2M85A 4ZQLA 2YURA 1WEPA 2CONA 4GB0A 2VJFB 2KR4A 2K4DA 4F52B 4I7CA 2ECGA 1WEWA 5D1LB 2ECVA 1VYXA 2ECIA 5C13A 1JOCA 1FBVA 2CSVA 2MD7B 2CSZA 4R2YA 2ECTA 2YHNA 3LQHA 4I7BA 4GNDA 4GNGA 2KU3A 2Y1NA 1DCQA 5LKZA 2LXHC 1IYMA 1N87A 5G0FA 2IQJA 2JRJA 2OWAA 2KKXA 4L7XA 4YABA 3M7KA 2LDRA 2KREA 3L1ZB 3FEHA 1WENA 2KWKA 3GV4A 2LAUA 5H1UA 2XOCA 4A49A 2BAYA 4A4BA 3SOUA 2MA6A 2NAAA 4ZDTA 4O62A 2MA5A 1WE9A 3RPGC 5TBNA 2M3HA 5KH3A 4B86C 2CKLB 2KE1A 1U6GB 4R8PK 2LXPC 3FM8C 2M13A 2KWOA 2CT2A 2VPDA 2Y1MA 3PURA 3DQVR 3M62A 2IDAA 5TRBA 5AITA 4CA1A 5B8DA 2VNFA 4O64A 5TDRA 3U5OA 2EA6A 2JUNA 3DDTA 2K1JA 1MM3A 1WIMA 3VK6A 3FJUB 1WEEA 4LLBA 2PNXA 2E61A 4FO9A 4YATA 5B78A 3U5MA 3HCSA 4A4CA 4TKPB 2KWNA 5J3XA 5C11A 2C2LA 1X4IA 2YT5A 2D8SA 2YSJA 4CCGX 3PUQA 2Y43A 5KH9A 2EGMA 3MDBC 4UP0A 4MSXA 2FUUA 3Q1DA 3JUEA 5D1KB 4N3WA 3ZVZB 2H0DA 2LGGA 2E6SA 2F42A 5DINA 2DJAA 3LRQA 5B77A 3N9QA 3IHPA 2VJEB 2EGPA 4LK9A 4A0CD 5B76A 5LKUA 2MUMA 5TDWA 2B0OE 2ECNA 3O35A 1E4UA 1X4JA 2RSDA 4IC2A 3ZNIA 2YHOA 4BBQA 1Z6UA 3U5NA 3HTKC 4AYCA 1Z2QA 4QQ4A 2YSMA 2L5UA 4WZ2A 2FUIA 5FEYA 3ZVYA 3RTRB 2YVRA 3N9PA 2HDPA 5SVIB 2KYUA 5H9MA 4FIPA 5SVYA 3KQIA 5FB1A 1JM7B 2ECJA 3LVQE 2XOZA 2JMIA 2KFTA 3SOWA 3H7HA 4Z0RA 4L58A 3O70A 2MD8C 2L7PA 2RR4A 2F6NA 3ZYQA 2LGVA 2KGGA 2CRRA 3M63A 1WEQA 4QF2A 3SUBA 4AVXA 1CHCA 2YW8A
chains in the Genus database with same CATH topology
2YREA 4QQ4A 3FM8C 3LVQE 2EXUA 2IQJA 2XOZA 2OWAA 4OGEA 2KKXA 2M13A 2JM3A 3M7KA 3LDYA 2XOYA 3E2DA 2MKEA 2DJAA 3FEHA 3H7HA 3O47A 2CSVA 4Z0RA 2LAUA 3PLWA 2XOCA 5SVIA 2L7PA 2D8UA 3DWDA 2P57A 3LJUX 5SVXA 2RR4A 4Z0OA 3Q1DA 3T9KA 4F1PA 2FD4A 3KDEC 2B0OE 2CRRA 2CRWA 2EGMA 2YVRA 2FFWA 3MDBC 4O62A 1DCQA 2CONA 2JUNA 3JUEA 5SVIB 3SUBA 3DDTA 3LVRE 5K3QA 2KKYA 3FJUB 4OGCA 5SVYA 2XP0A 2E61A 4H9DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XOY A;  2XP0 A;  2XOZ A;  2XOC A; 
#chains in the Genus database with same CATH topology
 2VJE A;  1XWH A;  4W4U A;  1LDK C;  3ZPV E;  4C9Z A;  1HYI A;  3E2D A;  4V3L C;  2VP7 A;  1WEO A;  3LQJ A;  5TAB A;  2VJF A;  4AP4 A;  3U5P A;  2YQL A;  2FD4 A;  1WEM A;  3FAN A;  2FSA A;  3EB5 A;  1WEU A;  3L11 A;  2YQM A;  4GNF A;  1WGM A;  1WIL A;  2EXU A;  5JG6 A;  2L0B A;  2PUY A;  2RI7 A;  3O47 A;  4IC3 A;  2UZG A;  2CSY A;  5LKT A;  5SVI A;  3DWD A;  4YAD A;  4QF3 A;  2MNZ A;  1HYJ A;  3T9K A;  3T7L A;  3LQI A;  4PPE A;  2VPB A;  3GL6 A;  4Q6F A;  2VPG A;  3SOX A;  3O37 A;  4OGE A;  3ZPV 1;  2LN0 A;  4YAX A;  4N4F A;  5LCW B;  1FP0 A;  1ZBD B;  3PLW A;  3O34 A;  1F62 A;  2CKL A;  1WFK A;  4S3O B;  1V87 A;  4LJN A;  2FFW A;  2L75 A;  5AIU A;  2YUC A;  1K2F A;  1DVP A;  4XI1 A;  2YYR A;  3LVR E;  5G05 B;  2KKY A;  3L1X A;  4NN2 A;  2XP0 A;  3NG2 A;  4LKA A;  2ECW A;  2DX8 A;  4WA6 A;  2OXQ C;  3C6W A;  3DPL R;  1RMD A;  2MKE A;  2XEU A;  3PHD A;  4R7E A;  5EYA F;  2KGI A;  2LGL A;  2M6M A;  3KV6 A;  3LJU X;  4YC9 A;  2I50 A;  4P5O B;  2CRW A;  3KNV A;  3HCT A;  2KIZ A;  2YRE A;  1X4U A;  4WZ3 B;  2K16 A;  2LRI C;  5LKX A;  4UI9 B;  5SVX A;  2EOD A;  2E6R A;  1VFY A;  1MM2 A;  1WES A;  2L43 A;  3FL2 A;  5B79 A;  3KV5 A;  3T6R A;  3QZV A;  5KH7 A;  2KWJ A;  4AUQ B;  1BOR A;  4YBS A;  3I2D A;  2K17 A;  2MIQ A;  1LDJ B;  2QJ0 A;  1WEV A;  2XOY A;  2G45 A;  2HYE D;  3V43 A;  2H0D B;  4ZUX U;  3KDE C;  5B75 A;  2L80 A;  5D1M B;  2MNY A;  5G04 B;  5FER A;  4H9D A;  4BHW A;  3MHS A;  5DKA A;  4S3O C;  4PTB A;  4UP5 A;  2AN6 A;  4YBT A;  3C5K A;  3LDY A;  3EB6 A;  4MVT A;  4AYC B;  2M1R A;  5FB0 A;  5I3L A;  2LGK A;  3O33 A;  4Z0O A;  4F1P A;  4V3K C;  1MBM A;  1JM7 A;  5H1V A;  2G43 A;  2QIC A;  3N9O A;  2XB1 A;  4I7D A;  5K3Q A;  4B7Y C;  3M99 A;  4GNE A;  2YU4 A;  2JMJ A;  3RPG B;  2QIZ A;  4WZ0 A;  2G6Q A;  3O36 A;  2DSM A;  2MT5 A;  4FK5 A;  3N9M A;  4YBM A;  2VPE A;  2D8U A;  1Z60 A;  2F6J A;  2C2V S;  3ZTG A;  4X3G A;  3N9N A;  5H1T A;  2ZET C;  2LV9 A;  4LAD B;  2JMD A;  4OGC A;  1VD4 A;  3N9L A;  3FAO A;  2JM3 A;  1G25 A;  3MHH A;  1T1H A;  4FJC A;  3O7A A;  2P57 A;  3SHB A;  2LQ6 A;  3ASL A;  3HCU A;  2M85 A;  4ZQL A;  2YUR A;  1WEP A;  2CON A;  4GB0 A;  2VJF B;  2KR4 A;  2K4D A;  4F52 B;  4I7C A;  2ECG A;  1WEW A;  5D1L B;  2ECV A;  1VYX A;  2ECI A;  5C13 A;  1JOC A;  1FBV A;  2CSV A;  2MD7 B;  2CSZ A;  4R2Y A;  2ECT A;  2YHN A;  3LQH A;  4I7B A;  4GND A;  4GNG A;  2KU3 A;  2Y1N A;  1DCQ A;  5LKZ A;  2LXH C;  1IYM A;  1N87 A;  5G0F A;  2IQJ A;  2JRJ A;  2OWA A;  2KKX A;  4L7X A;  4YAB A;  3M7K A;  2LDR A;  2KRE A;  3L1Z B;  3FEH A;  1WEN A;  2KWK A;  3GV4 A;  2LAU A;  5H1U A;  2XOC A;  4A49 A;  2BAY A;  4A4B A;  3SOU A;  2MA6 A;  2NAA A;  4ZDT A;  4O62 A;  2MA5 A;  1WE9 A;  3RPG C;  5TBN A;  2M3H A;  5KH3 A;  4B86 C;  2CKL B;  2KE1 A;  1U6G B;  4R8P K;  2LXP C;  3FM8 C;  2M13 A;  2KWO A;  2CT2 A;  2VPD A;  2Y1M A;  3PUR A;  3DQV R;  3M62 A;  2IDA A;  5TRB A;  5AIT A;  4CA1 A;  5B8D A;  2VNF A;  4O64 A;  5TDR A;  3U5O A;  2EA6 A;  2JUN A;  3DDT A;  2K1J A;  1MM3 A;  1WIM A;  3VK6 A;  3FJU B;  1WEE A;  4LLB A;  2PNX A;  2E61 A;  4FO9 A;  4YAT A;  5B78 A;  3U5M A;  3HCS A;  4A4C A;  4TKP B;  2KWN A;  5J3X A;  5C11 A;  2C2L A;  1X4I A;  2YT5 A;  2D8S A;  2YSJ A;  4CCG X;  3PUQ A;  2Y43 A;  5KH9 A;  2EGM A;  3MDB C;  4UP0 A;  4MSX A;  2FUU A;  3Q1D A;  3JUE A;  5D1K B;  4N3W A;  3ZVZ B;  2H0D A;  2LGG A;  2E6S A;  2F42 A;  5DIN A;  2DJA A;  3LRQ A;  5B77 A;  3N9Q A;  3IHP A;  2VJE B;  2EGP A;  4LK9 A;  4A0C D;  5B76 A;  5LKU A;  2MUM A;  5TDW A;  2B0O E;  2ECN A;  3O35 A;  1E4U A;  1X4J A;  2RSD A;  4IC2 A;  3ZNI A;  2YHO A;  4BBQ A;  1Z6U A;  3U5N A;  3HTK C;  4AYC A;  1Z2Q A;  4QQ4 A;  2YSM A;  2L5U A;  4WZ2 A;  2FUI A;  5FEY A;  3ZVY A;  3RTR B;  2YVR A;  3N9P A;  2HDP A;  5SVI B;  2KYU A;  5H9M A;  4FIP A;  5SVY A;  3KQI A;  5FB1 A;  1JM7 B;  2ECJ A;  3LVQ E;  2XOZ A;  2JMI A;  2KFT A;  3SOW A;  3H7H A;  4Z0R A;  4L58 A;  3O70 A;  2MD8 C;  2L7P A;  2RR4 A;  2F6N A;  3ZYQ A;  2LGV A;  2KGG A;  2CRR A;  3M63 A;  1WEQ A;  4QF2 A;  3SUB A;  4AVX A;  1CHC A;  2YW8 A; 
#chains in the Genus database with same CATH homology
 2YRE A;  4QQ4 A;  3FM8 C;  3LVQ E;  2EXU A;  2IQJ A;  2XOZ A;  2OWA A;  4OGE A;  2KKX A;  2M13 A;  2JM3 A;  3M7K A;  3LDY A;  2XOY A;  3E2D A;  2MKE A;  2DJA A;  3FEH A;  3H7H A;  3O47 A;  2CSV A;  4Z0R A;  2LAU A;  3PLW A;  2XOC A;  5SVI A;  2L7P A;  2D8U A;  3DWD A;  2P57 A;  3LJU X;  5SVX A;  2RR4 A;  4Z0O A;  3Q1D A;  3T9K A;  4F1P A;  2FD4 A;  3KDE C;  2B0O E;  2CRR A;  2CRW A;  2EGM A;  2YVR A;  2FFW A;  3MDB C;  4O62 A;  1DCQ A;  2CON A;  2JUN A;  3JUE A;  5SVI B;  3SUB A;  3DDT A;  3LVR E;  5K3Q A;  2KKY A;  3FJU B;  4OGC A;  5SVY A;  2XP0 A;  2E61 A;  4H9D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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