2JUNA

Structure of the mid1 tandem b-boxes reveals an interaction reminiscent of intermolecular ring heterodimers
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
101
structure length
101
Chain Sequence
AEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the MID1 Tandem B-Boxes Reveals an Interaction Reminiscent of Intermolecular Ring Heterodimers
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords Midline-1
total genus 12
structure length 101
sequence length 101
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2007-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00643 zf-B_box B-box zinc finger
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.200 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Herpes Virus-1 2junA00
2CSVA 2JUNA 2YVRA 5K3QA 2EGMA 2DJAA 3Q1DA 3DDTA 2D8UA
chains in the Genus database with same CATH superfamily
2FFWA 2JUNA 5DINA 4CCGX 5JG6A 4YAXA 2M13A 2DX8A 5TDWA 2KIZA 4PTBA 5SVYA 2VPEA 3NG2A 3SUBA 2QJ0A 4FK5A 1X4IA 2D8UA 2JMDA 3ZTGA 2KYUA 3FANA 5B8DA 1K2FA 2UZGA 4F52B 3MHHA 1LDKC 1VD4A 1WEUA 2YW8A 3LVRE 4ZUXU 1Z60A 3L1XA 4ZQLA 4WZ3B 4YBTA 5AIUA 2MNZA 3O36A 2LXHC 3FJUB 2EXUA 2L80A 2LXPC 2YREA 2H0DA 1WE9A 4YC9A 1JOCA 2KE1A 2F6NA 4ZDTA 1JM7B 2OXQC 2KKYA 2VPGA 4P5OB 3RPGB 3VK6A 1E4UA 2KWNA 5G05B 2M3HA 3PUQA 2YQLA 2L5UA 4A4CA 2MUMA 1RMDA 1X4JA 2YURA 4V3KC 4IC2A 3LJUX 4Z0RA 3QZVA 2YVRA 3O33A 2CRRA 2ECGA 2KR4A 1WGMA 3EB6A 5KH3A 3M99A 1VFYA 3FEHA 4LJNA 2ECJA 1ZBDB 4LKAA 5LKTA 2MIQA 3LVQE 3V43A 2MA6A 3T7LA 3ASLA 3E2DA 3M7KA 2M1RA 2YHOA 3GV4A 3U5OA 3DDTA 2JMIA 3KQIA 4L58A 4Q6FA 3H7HA 1JM7A 4Z0OA 2L75A 2K16A 4R7EA 5D1LB 5FB1A 2E61A 5LKXA 2CKLB 3M63A 2F42A 2RR4A 4PPEA 1FBVA 5H1VA 2L43A 2LQ6A 3ZVZB 3SHBA 2CONA 2LDRA 3N9NA 1DCQA 3ZPV1 3C6WA 2KGGA 4I7CA 4CA1A 2K1JA 5LCWB 2L0BA 2L7PA 2ECNA 5G0FA 5B78A 3RPGC 2VP7A 2VJEA 4GNGA 3DPLR 5FERA 2BAYA 3LQJA 4O64A 5I3LA 1WEVA 2JRJA 2YQMA 4TKPB 2MA5A 2G43A 2D8SA 1IYMA 4QF2A 3N9MA 3ZYQA 2C2VS 4AYCB 3EB5A 3FL2A 2LGLA 2YYRA 4H9DA 4BBQA 3LRQA 3MDBC 2CKLA 5AITA 1WENA 2QICA 4GNEA 4S3OB 2MD7B 3M62A 2JM3A 1VYXA 2G6QA 2KWJA 2YSMA 3L11A 4N4FA 2ECTA 3I2DA 2MD8C 2Y1NA 2LV9A 3PURA 1WEWA 2XP0A 3KNVA 2XEUA 5H1TA 4YABA 4LK9A 4B7YC 3ZNIA 1HYJA 2VNFA 3C5KA 2PUYA 4AYCA 1F62A 2EGMA 4B86C 4LADB 4XI1A 2VJEB 2FUIA 3DWDA 5G04B 4W4UA 4V3LC 4NN2A 1LDJB 5J3XA 2F6JA 2FSAA 5TABA 1WILA 3T6RA 1V87A 3HCSA 3LQIA 4QF3A 2CSZA 3ZPVE 2K17A 5TRBA 3N9PA 2LGGA 3HCTA 2KKXA 1WEMA 2JMJA 4I7BA 5H9MA 4S3OC 3GL6A 3FM8C 3N9LA 3FAOA 4UP0A 2VJFB 1X4UA 2KWKA 4WZ2A 5D1KB 4F1PA 1FP0A 2KREA 2MT5A 5C11A 3O35A 2B0OE 5D1MB 5LKUA 2IQJA 4BHWA 2EODA 2YU4A 2MKEA 5K3QA 5SVIA 3SOUA 2M85A 2YHNA 4YADA 1N87A 4QQ4A 2XOCA 2HYED 2KFTA 4AP4A 3HTKC 5B75A 3O37A 3T9KA 3HCUA 4FO9A 2KGIA 2ZETC 3O47A 3KV6A 1G25A 4AVXA 2I50A 2KU3A 2DJAA 2ECWA 5C13A 2MNYA 4OGCA 2XOYA 3Q1DA 5FB0A 4GNFA 2KWOA 3JUEA 5FEYA 4C9ZA 3L1ZB 2VJFA 3O70A 2HDPA 3DQVR 4MSXA 4R2YA 3O7AA 4FJCA 2LAUA 3U5MA 5EYAF 2E6SA 4UI9B 4OGEA 3ZVYA 3IHPA 1MM3A 3N9QA 2VPBA 5KH7A 1WEOA 3U5PA 5DKAA 5TBNA 2Y43A 5B79A 2PNXA 1Z6UA 4X3GA 2AN6A 3PHDA 1CHCA 2IDAA 1U6GB 3N9OA 3MHSA 1WEEA 4UP5A 2XB1A 2RI7A 2CSVA 4WA6A 2C2LA 2QIZA 4IC3A 4A0CD 1MM2A 4MVTA 2E6RA 2EA6A 3SOXA 5SVIB 2DSMA 1Z2QA 4A4BA 1BORA 3PLWA 3U5NA 2CRWA 4YATA 2FUUA 2NAAA 4YBMA 1MBMA 2YUCA 1WEPA 1WEQA 2CSYA 1HYIA 4R8PK 4GNDA 2LGKA 4YBSA 2M6MA 5B76A 1DVPA 3KV5A 2K4DA 2Y1MA 2ECIA 2VPDA 2YSJA 5H1UA 5KH9A 4GB0A 1XWHA 5LKZA 2G45A 2YT5A 2LGVA 4LLBA 4FIPA 4A49A 2RSDA 2FD4A 4I7DA 3KDEC 2CT2A 4L7XA 2LN0A 2EGPA 3SOWA 3LDYA 4N3WA 2P57A 5B77A 2ECVA 2XOZA 2LRIC 1WFKA 4O62A 3RTRB 2OWAA 2H0DB 3O34A 1WESA 5TDRA 1WIMA 4AUQB 3LQHA 5SVXA 4WZ0A 1T1HA
chains in the Genus database with same CATH topology
2FFWA 2CSVA 2JUNA 2RR4A 4OGCA 3LVRE 4OGEA 2XOYA 2B0OE 3KDEC 2M13A 2XP0A 3Q1DA 2IQJA 3FM8C 2CONA 5SVYA 3JUEA 2MKEA 5K3QA 3LDYA 5SVIA 3SUBA 3FEHA 1DCQA 5SVIB 3FJUB 2EXUA 3LVQE 4QQ4A 2JM3A 2P57A 2D8UA 2XOZA 2XOCA 3MDBC 3PLWA 3E2DA 3M7KA 4O62A 2CRWA 3LJUX 2YREA 4F1PA 4Z0RA 2OWAA 2EGMA 2L7PA 3DDTA 3T9KA 3H7HA 2YVRA 3O47A 2KKXA 4H9DA 4Z0OA 2LAUA 2CRRA 2KKYA 3DWDA 5SVXA 2FD4A 2E61A 2DJAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CSV A;  2JUN A;  2YVR A;  5K3Q A;  2EGM A;  2DJA A;  3Q1D A;  3DDT A;  2D8U A; 
#chains in the Genus database with same CATH topology
 2FFW A;  2JUN A;  5DIN A;  4CCG X;  5JG6 A;  4YAX A;  2M13 A;  2DX8 A;  5TDW A;  2KIZ A;  4PTB A;  5SVY A;  2VPE A;  3NG2 A;  3SUB A;  2QJ0 A;  4FK5 A;  1X4I A;  2D8U A;  2JMD A;  3ZTG A;  2KYU A;  3FAN A;  5B8D A;  1K2F A;  2UZG A;  4F52 B;  3MHH A;  1LDK C;  1VD4 A;  1WEU A;  2YW8 A;  3LVR E;  4ZUX U;  1Z60 A;  3L1X A;  4ZQL A;  4WZ3 B;  4YBT A;  5AIU A;  2MNZ A;  3O36 A;  2LXH C;  3FJU B;  2EXU A;  2L80 A;  2LXP C;  2YRE A;  2H0D A;  1WE9 A;  4YC9 A;  1JOC A;  2KE1 A;  2F6N A;  4ZDT A;  1JM7 B;  2OXQ C;  2KKY A;  2VPG A;  4P5O B;  3RPG B;  3VK6 A;  1E4U A;  2KWN A;  5G05 B;  2M3H A;  3PUQ A;  2YQL A;  2L5U A;  4A4C A;  2MUM A;  1RMD A;  1X4J A;  2YUR A;  4V3K C;  4IC2 A;  3LJU X;  4Z0R A;  3QZV A;  2YVR A;  3O33 A;  2CRR A;  2ECG A;  2KR4 A;  1WGM A;  3EB6 A;  5KH3 A;  3M99 A;  1VFY A;  3FEH A;  4LJN A;  2ECJ A;  1ZBD B;  4LKA A;  5LKT A;  2MIQ A;  3LVQ E;  3V43 A;  2MA6 A;  3T7L A;  3ASL A;  3E2D A;  3M7K A;  2M1R A;  2YHO A;  3GV4 A;  3U5O A;  3DDT A;  2JMI A;  3KQI A;  4L58 A;  4Q6F A;  3H7H A;  1JM7 A;  4Z0O A;  2L75 A;  2K16 A;  4R7E A;  5D1L B;  5FB1 A;  2E61 A;  5LKX A;  2CKL B;  3M63 A;  2F42 A;  2RR4 A;  4PPE A;  1FBV A;  5H1V A;  2L43 A;  2LQ6 A;  3ZVZ B;  3SHB A;  2CON A;  2LDR A;  3N9N A;  1DCQ A;  3ZPV 1;  3C6W A;  2KGG A;  4I7C A;  4CA1 A;  2K1J A;  5LCW B;  2L0B A;  2L7P A;  2ECN A;  5G0F A;  5B78 A;  3RPG C;  2VP7 A;  2VJE A;  4GNG A;  3DPL R;  5FER A;  2BAY A;  3LQJ A;  4O64 A;  5I3L A;  1WEV A;  2JRJ A;  2YQM A;  4TKP B;  2MA5 A;  2G43 A;  2D8S A;  1IYM A;  4QF2 A;  3N9M A;  3ZYQ A;  2C2V S;  4AYC B;  3EB5 A;  3FL2 A;  2LGL A;  2YYR A;  4H9D A;  4BBQ A;  3LRQ A;  3MDB C;  2CKL A;  5AIT A;  1WEN A;  2QIC A;  4GNE A;  4S3O B;  2MD7 B;  3M62 A;  2JM3 A;  1VYX A;  2G6Q A;  2KWJ A;  2YSM A;  3L11 A;  4N4F A;  2ECT A;  3I2D A;  2MD8 C;  2Y1N A;  2LV9 A;  3PUR A;  1WEW A;  2XP0 A;  3KNV A;  2XEU A;  5H1T A;  4YAB A;  4LK9 A;  4B7Y C;  3ZNI A;  1HYJ A;  2VNF A;  3C5K A;  2PUY A;  4AYC A;  1F62 A;  2EGM A;  4B86 C;  4LAD B;  4XI1 A;  2VJE B;  2FUI A;  3DWD A;  5G04 B;  4W4U A;  4V3L C;  4NN2 A;  1LDJ B;  5J3X A;  2F6J A;  2FSA A;  5TAB A;  1WIL A;  3T6R A;  1V87 A;  3HCS A;  3LQI A;  4QF3 A;  2CSZ A;  3ZPV E;  2K17 A;  5TRB A;  3N9P A;  2LGG A;  3HCT A;  2KKX A;  1WEM A;  2JMJ A;  4I7B A;  5H9M A;  4S3O C;  3GL6 A;  3FM8 C;  3N9L A;  3FAO A;  4UP0 A;  2VJF B;  1X4U A;  2KWK A;  4WZ2 A;  5D1K B;  4F1P A;  1FP0 A;  2KRE A;  2MT5 A;  5C11 A;  3O35 A;  2B0O E;  5D1M B;  5LKU A;  2IQJ A;  4BHW A;  2EOD A;  2YU4 A;  2MKE A;  5K3Q A;  5SVI A;  3SOU A;  2M85 A;  2YHN A;  4YAD A;  1N87 A;  4QQ4 A;  2XOC A;  2HYE D;  2KFT A;  4AP4 A;  3HTK C;  5B75 A;  3O37 A;  3T9K A;  3HCU A;  4FO9 A;  2KGI A;  2ZET C;  3O47 A;  3KV6 A;  1G25 A;  4AVX A;  2I50 A;  2KU3 A;  2DJA A;  2ECW A;  5C13 A;  2MNY A;  4OGC A;  2XOY A;  3Q1D A;  5FB0 A;  4GNF A;  2KWO A;  3JUE A;  5FEY A;  4C9Z A;  3L1Z B;  2VJF A;  3O70 A;  2HDP A;  3DQV R;  4MSX A;  4R2Y A;  3O7A A;  4FJC A;  2LAU A;  3U5M A;  5EYA F;  2E6S A;  4UI9 B;  4OGE A;  3ZVY A;  3IHP A;  1MM3 A;  3N9Q A;  2VPB A;  5KH7 A;  1WEO A;  3U5P A;  5DKA A;  5TBN A;  2Y43 A;  5B79 A;  2PNX A;  1Z6U A;  4X3G A;  2AN6 A;  3PHD A;  1CHC A;  2IDA A;  1U6G B;  3N9O A;  3MHS A;  1WEE A;  4UP5 A;  2XB1 A;  2RI7 A;  2CSV A;  4WA6 A;  2C2L A;  2QIZ A;  4IC3 A;  4A0C D;  1MM2 A;  4MVT A;  2E6R A;  2EA6 A;  3SOX A;  5SVI B;  2DSM A;  1Z2Q A;  4A4B A;  1BOR A;  3PLW A;  3U5N A;  2CRW A;  4YAT A;  2FUU A;  2NAA A;  4YBM A;  1MBM A;  2YUC A;  1WEP A;  1WEQ A;  2CSY A;  1HYI A;  4R8P K;  4GND A;  2LGK A;  4YBS A;  2M6M A;  5B76 A;  1DVP A;  3KV5 A;  2K4D A;  2Y1M A;  2ECI A;  2VPD A;  2YSJ A;  5H1U A;  5KH9 A;  4GB0 A;  1XWH A;  5LKZ A;  2G45 A;  2YT5 A;  2LGV A;  4LLB A;  4FIP A;  4A49 A;  2RSD A;  2FD4 A;  4I7D A;  3KDE C;  2CT2 A;  4L7X A;  2LN0 A;  2EGP A;  3SOW A;  3LDY A;  4N3W A;  2P57 A;  5B77 A;  2ECV A;  2XOZ A;  2LRI C;  1WFK A;  4O62 A;  3RTR B;  2OWA A;  2H0D B;  3O34 A;  1WES A;  5TDR A;  1WIM A;  4AUQ B;  3LQH A;  5SVX A;  4WZ0 A;  1T1H A; 
#chains in the Genus database with same CATH homology
 2FFW A;  2CSV A;  2JUN A;  2RR4 A;  4OGC A;  3LVR E;  4OGE A;  2XOY A;  2B0O E;  3KDE C;  2M13 A;  2XP0 A;  3Q1D A;  2IQJ A;  3FM8 C;  2CON A;  5SVY A;  3JUE A;  2MKE A;  5K3Q A;  3LDY A;  5SVI A;  3SUB A;  3FEH A;  1DCQ A;  5SVI B;  3FJU B;  2EXU A;  3LVQ E;  4QQ4 A;  2JM3 A;  2P57 A;  2D8U A;  2XOZ A;  2XOC A;  3MDB C;  3PLW A;  3E2D A;  3M7K A;  4O62 A;  2CRW A;  3LJU X;  2YRE A;  4F1P A;  4Z0R A;  2OWA A;  2EGM A;  2L7P A;  3DDT A;  3T9K A;  3H7H A;  2YVR A;  3O47 A;  2KKX A;  4H9D A;  4Z0O A;  2LAU A;  2CRR A;  2KKY A;  3DWD A;  5SVX A;  2FD4 A;  2E61 A;  2DJA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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