2VJEA

Crystal structure of the mdm2-mdmx ring domain heterodimer
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
60
structure length
60
Chain Sequence
LNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE MDM2
total genus 12
structure length 60
sequence length 60
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2007-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13920 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.10 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Zinc/RING finger domain, C3HC4 (zinc finger) 2vjeA00
1VYXA 4YADA 3LRQA 2YSMA 4MSXA 2CSZA 2ECVA 2Y1MA 1WE9A 2EODA 1VD4A 1JOCA 2KREA 4ZDTA 3ZVZB 3U5OA 2JMJA 3L1XA 5B76A 2YSJA 3LQJA 2VJFB 4S3OB 4PTBA 5TBNA 2HYED 3RTRB 2FUIA 3QZVA 4YBMA 3M62A 4V3LC 4I7BA 3U5MA 3L1ZB 2C2VS 3VK6A 2I50A 3GV4A 2KU3A 2CT2A 4R7EA 1WEEA 2F6JA 3ASLA 5DKAA 2L5UA 4L58A 1XWHA 4C9ZA 2KWJA 2YHNA 3N9OA 5KH3A 1WEMA 3V43A 1WEOA 4AVXA 4TKPB 4FO9A 2YREA 2KGIA 2VP7A 2K17A 2MUMA 5TDWA 2C2LA 3KV5A 3HCUA 2KWKA 1F62A 3PURA 2LRIC 2YUCA 3ZPV1 5TABA 4O64A 2VPEA 5B79A 3O7AA 2G6QA 2M3HA 5LKTA 2YT5A 4A4CA 3M99A 4LADB 3EB6A 1X4JA 3N9MA 4QF3A 1WENA 1RMDA 3KQIA 5KH9A 3ZYQA 2LGVA 5B8DA 2L43A 2VJFA 2ZETC 3SOWA 5I3LA 5TDRA 3ZNIA 5H1TA 2JMDA 3O33A 5H1VA 2EGPA 1T1HA 2XB1A 2F42A 5B75A 4WZ0A 3LQIA 3U5NA 4R8PK 1X4IA 3O34A 2KYUA 2K16A 1DVPA 3O70A 4I7DA 2KIZA 2DX8A 1FBVA 1WESA 4W4UA 2MNZA 2KWOA 2HDPA 4GNGA 4GNDA 5FERA 4ZQLA 4X3GA 3ZTGA 4PPEA 1U6GB 4AP4A 3ZPVE 3PHDA 1G25A 3O37A 2OXQC 2LN0A 3HCSA 3HCTA 1MM2A 3N9QA 4IC2A 4YAXA 1Z60A 3SOUA 4F52B 5D1MB 4Q6FA 2LDRA 5LKUA 5D1KB 2LGKA 2KWNA 2CSYA 4XI1A 4N3WA 5FB0A 4V3KC 3SOXA 5G04B 5G0FA 3C5KA 2VNFA 4GNFA 2Y43A 2IDAA 2JMIA 2ECJA 2ECWA 3T6RA 2L0BA 3SHBA 4A49A 2LV9A 2QJ0A 4WZ3B 2MIQA 5H9MA 1WEQA 1N87A 3L11A 2YHOA 1ZBDB 2H0DA 4NN2A 1LDJB 2BAYA 1WEVA 2XEUA 4B86C 2ECTA 3KV6A 4N4FA 4L7XA 4LLBA 2KE1A 3RPGB 4YATA 3KNVA 2RI7A 2YQMA 2VJEB 2CKLA 2YYRA 3N9PA 3O36A 4FJCA 3IHPA 5AIUA 4UP5A 2H0DB 2MT5A 5LCWB 4MVTA 3T7LA 2VPBA 2MA5A 1WEWA 2YW8A 4I7CA 5FB1A 1BORA 2LXPC 2FUUA 5D1LB 3I2DA 4LKAA 3PUQA 1CHCA 2MD7B 2M1RA 2ECNA 2CKLB 3U5PA 3RPGC 3O35A 1LDKC 2L75A 3LQHA 1WILA 4FIPA 4IC3A 4YC9A 3MHHA 2F6NA 2PUYA 4UI9B 5C13A 1JM7B 2QIZA 1K2FA 1WEUA 4CCGX 3HTKC 2Y1NA 2M6MA 5KH7A 2FSAA 2QICA 2LXHC 2KR4A 3EB5A 2ECGA 3M63A 2E6SA 5LKXA 5EYAF 4P5OB 1WFKA 5H1UA 2UZGA 2NAAA 2VJEA 1X4UA 1FP0A 4LK9A 1WIMA 1HYIA 3ZVYA 5B78A 1IYMA 4R2YA 1HYJA 2D8SA 4YBTA 4A0CD 1V87A 4ZUXU 3MHSA 4WZ2A 2YU4A 4YBSA 2LGLA 5AITA 5TRBA 2VPGA 3NG2A 4GB0A 4S3OC 1WGMA 2YQLA 3DPLR 4BBQA 3GL6A 2L80A 2G45A 2VPDA 5DINA 4AYCA 2JRJA 2AN6A 4GNEA 2YURA 2MD8C 3DQVR 1VFYA 1Z6UA 1Z2QA 4YABA 5J3XA 5B77A 3N9NA 1MM3A 2PNXA 2G43A 4FK5A 3FL2A 4AUQB 5G05B 2K1JA 4QF2A 2KFTA 5JG6A 1WEPA 2K4DA 2LGGA 4UP0A 2MA6A 4B7YC 2E6RA 2ECIA 1JM7A 2EA6A 2LQ6A 2M85A 2KGGA 4CA1A 4A4BA 4AYCB 2RSDA 4LJNA 4WA6A 5FEYA 5C11A 1E4UA 4BHWA 5LKZA 2MNYA 3N9LA 3C6WA
chains in the Genus database with same CATH superfamily
2B0OE 1VYXA 4YADA 3LRQA 2YSMA 4MSXA 2CSZA 2XP0A 2ECVA 2Y1MA 1WE9A 2EODA 1VD4A 1JOCA 2KREA 4ZDTA 3ZVZB 3U5OA 2JMJA 3L1XA 3DWDA 2YSJA 5B76A 3LQJA 4H9DA 2VJFB 4S3OB 4PTBA 5TBNA 2YVRA 4Z0OA 2HYED 3RTRB 2FUIA 3QZVA 4YBMA 3M62A 4V3LC 4I7BA 3U5MA 3L1ZB 2C2VS 3VK6A 2I50A 3GV4A 2KU3A 2CT2A 4R7EA 1WEEA 2F6JA 3ASLA 5DKAA 2L5UA 4L58A 1XWHA 4C9ZA 2KWJA 2YHNA 3N9OA 5KH3A 1WEMA 3V43A 1WEOA 4AVXA 4TKPB 4FO9A 2XOCA 2YREA 2KGIA 2VP7A 2K17A 2MUMA 5TDWA 2C2LA 3KV5A 3HCUA 2KWKA 1F62A 3PURA 2EGMA 2LRIC 4OGEA 2YUCA 3ZPV1 3E2DA 5TABA 4O64A 2VPEA 5B79A 3O7AA 2G6QA 2M3HA 5LKTA 2YT5A 4A4CA 3M99A 4LADB 2RR4A 3EB6A 1X4JA 3N9MA 4QF3A 1WENA 1RMDA 5SVXA 3KQIA 5KH9A 3ZYQA 2LGVA 5B8DA 2L43A 2VJFA 2CRWA 2ZETC 3SOWA 5I3LA 5TDRA 3ZNIA 5H1TA 2JMDA 3O33A 5H1VA 2EGPA 1T1HA 2XB1A 2XOZA 2F42A 5B75A 4WZ0A 3LQIA 3U5NA 4R8PK 1X4IA 3O34A 2KYUA 3H7HA 3KDEC 2K16A 2JUNA 1DVPA 3O70A 4I7DA 3LDYA 2KIZA 2DX8A 1FBVA 1WESA 4W4UA 2MNZA 3FAOA 2KWOA 2HDPA 4GNGA 4GNDA 5FERA 4ZQLA 4X3GA 3ZTGA 5SVYA 4PPEA 1U6GB 4AP4A 3ZPVE 3PHDA 1G25A 3O37A 2OXQC 2LN0A 3HCSA 3HCTA 1MM2A 4O62A 3N9QA 4IC2A 4YAXA 1Z60A 3SOUA 4F52B 3FJUB 2D8UA 2JM3A 5D1MB 4Q6FA 2LDRA 4Z0RA 5LKUA 5D1KB 2LGKA 2KWNA 2CSYA 4XI1A 4N3WA 5FB0A 4V3KC 3SOXA 5G04B 5G0FA 3C5KA 2VNFA 4GNFA 2Y43A 2IDAA 2JMIA 2CRRA 2ECJA 2ECWA 3T6RA 2L0BA 2KKYA 3SHBA 4A49A 2LV9A 2QJ0A 4WZ3B 2MIQA 5H9MA 1WEQA 1N87A 3L11A 2YHOA 3LJUX 3T9KA 1ZBDB 2H0DA 1DCQA 4NN2A 1LDJB 2BAYA 3Q1DA 1WEVA 3FEHA 2XEUA 4B86C 2ECTA 3KV6A 4N4FA 4L7XA 4LLBA 2KE1A 3RPGB 2DSMA 3KNVA 4YATA 5K3QA 2RI7A 2YQMA 2VJEB 4F1PA 2CONA 2CKLA 2YYRA 3O47A 2FFWA 3N9PA 3O36A 4FJCA 4QQ4A 3IHPA 5AIUA 2XOYA 4UP5A 2DJAA 2H0DB 2MT5A 5LCWB 4MVTA 3T7LA 2VPBA 2MA5A 1WEWA 2YW8A 4I7CA 5FB1A 1BORA 2LXPC 2FUUA 5D1LB 3I2DA 4LKAA 3PUQA 3FM8C 1CHCA 2MD7B 2M1RA 2LAUA 2ECNA 2CKLB 3U5PA 3RPGC 3O35A 1LDKC 2L75A 3LQHA 1WILA 3SUBA 4FIPA 4IC3A 4YC9A 3MHHA 2F6NA 2PUYA 4UI9B 5C13A 1JM7B 2QIZA 1K2FA 1WEUA 4CCGX 2E61A 3HTKC 3DDTA 3FANA 2EXUA 3LVQE 2Y1NA 3JUEA 2M6MA 5KH7A 2FSAA 2QICA 2LXHC 2KR4A 1MBMA 3EB5A 2ECGA 3M63A 2E6SA 2M13A 5LKXA 2L7PA 5EYAF 4P5OB 1WFKA 5H1UA 2UZGA 2NAAA 2OWAA 2VJEA 1X4UA 1FP0A 4LK9A 1WIMA 1HYIA 3ZVYA 5B78A 1IYMA 4R2YA 2FD4A 1HYJA 2D8SA 4YBTA 4A0CD 1V87A 4ZUXU 3LVRE 3MHSA 4WZ2A 2YU4A 4YBSA 2LGLA 5AITA 5TRBA 2CSVA 2VPGA 3NG2A 3M7KA 4GB0A 4S3OC 1WGMA 2YQLA 3DPLR 4BBQA 3PLWA 3MDBC 3GL6A 2L80A 2G45A 2VPDA 5DINA 4AYCA 2KKXA 2JRJA 2AN6A 4GNEA 2YURA 2MD8C 3DQVR 1VFYA 4OGCA 1Z6UA 1Z2QA 4YABA 5J3XA 5B77A 3N9NA 1MM3A 2PNXA 2G43A 4FK5A 3FL2A 4AUQB 5G05B 2K1JA 2IQJA 4QF2A 5SVIA 2KFTA 5JG6A 1WEPA 2K4DA 2LGGA 4UP0A 2MA6A 4B7YC 2E6RA 2ECIA 1JM7A 2EA6A 2P57A 2LQ6A 2M85A 2KGGA 4CA1A 4A4BA 4AYCB 2RSDA 4LJNA 4WA6A 2MKEA 5FEYA 5C11A 1E4UA 4BHWA 5LKZA 2MNYA 5SVIB 3N9LA 3C6WA
chains in the Genus database with same CATH topology
1VYXA 4YADA 3LRQA 2YSMA 4MSXA 2CSZA 2ECVA 2Y1MA 1WE9A 2EODA 1VD4A 1JOCA 2KREA 4ZDTA 3ZVZB 3U5OA 2JMJA 3L1XA 5B76A 2YSJA 3LQJA 2VJFB 4S3OB 4PTBA 5TBNA 2HYED 3RTRB 2FUIA 3QZVA 4YBMA 3M62A 4V3LC 4I7BA 3U5MA 3L1ZB 2C2VS 3VK6A 2I50A 3GV4A 2KU3A 2CT2A 4R7EA 1WEEA 2F6JA 3ASLA 5DKAA 2L5UA 4L58A 1XWHA 4C9ZA 2KWJA 2YHNA 3N9OA 5KH3A 1WEMA 3V43A 1WEOA 4AVXA 4TKPB 4FO9A 2YREA 2KGIA 2VP7A 2K17A 2MUMA 5TDWA 2C2LA 3KV5A 3HCUA 2KWKA 1F62A 3PURA 2LRIC 2YUCA 3ZPV1 5TABA 4O64A 2VPEA 5B79A 3O7AA 2G6QA 2M3HA 5LKTA 2YT5A 4A4CA 3M99A 4LADB 3EB6A 1X4JA 3N9MA 4QF3A 1WENA 1RMDA 3KQIA 5KH9A 3ZYQA 2LGVA 5B8DA 2L43A 2VJFA 2ZETC 3SOWA 5I3LA 5TDRA 3ZNIA 5H1TA 2JMDA 3O33A 5H1VA 2EGPA 1T1HA 2XB1A 2F42A 5B75A 4WZ0A 3LQIA 3U5NA 4R8PK 1X4IA 3O34A 2KYUA 2K16A 1DVPA 3O70A 4I7DA 2KIZA 2DX8A 1FBVA 1WESA 4W4UA 2MNZA 2KWOA 2HDPA 4GNGA 4GNDA 5FERA 4ZQLA 4X3GA 3ZTGA 4PPEA 1U6GB 4AP4A 3ZPVE 3PHDA 1G25A 3O37A 2OXQC 2LN0A 3HCSA 3HCTA 1MM2A 3N9QA 4IC2A 4YAXA 1Z60A 3SOUA 4F52B 5D1MB 4Q6FA 2LDRA 5LKUA 5D1KB 2LGKA 2KWNA 2CSYA 4XI1A 4N3WA 5FB0A 4V3KC 3SOXA 5G04B 5G0FA 3C5KA 2VNFA 4GNFA 2Y43A 2IDAA 2JMIA 2ECJA 2ECWA 3T6RA 2L0BA 3SHBA 4A49A 2LV9A 2QJ0A 4WZ3B 2MIQA 5H9MA 1WEQA 1N87A 3L11A 2YHOA 1ZBDB 2H0DA 4NN2A 1LDJB 2BAYA 1WEVA 2XEUA 4B86C 2ECTA 3KV6A 4N4FA 4L7XA 4LLBA 2KE1A 3RPGB 4YATA 3KNVA 2RI7A 2YQMA 2VJEB 2CKLA 2YYRA 3N9PA 3O36A 4FJCA 3IHPA 5AIUA 4UP5A 2H0DB 2MT5A 5LCWB 4MVTA 3T7LA 2VPBA 2MA5A 1WEWA 2YW8A 4I7CA 5FB1A 1BORA 2LXPC 2FUUA 5D1LB 3I2DA 4LKAA 3PUQA 1CHCA 2MD7B 2M1RA 2ECNA 2CKLB 3U5PA 3RPGC 3O35A 1LDKC 2L75A 3LQHA 1WILA 4FIPA 4IC3A 4YC9A 3MHHA 2F6NA 2PUYA 4UI9B 5C13A 1JM7B 2QIZA 1K2FA 1WEUA 4CCGX 3HTKC 2Y1NA 2M6MA 5KH7A 2FSAA 2QICA 2LXHC 2KR4A 3EB5A 2ECGA 3M63A 2E6SA 5LKXA 5EYAF 4P5OB 1WFKA 5H1UA 2UZGA 2NAAA 2VJEA 1X4UA 1FP0A 4LK9A 1WIMA 1HYIA 3ZVYA 5B78A 1IYMA 4R2YA 1HYJA 2D8SA 4YBTA 4A0CD 1V87A 4ZUXU 3MHSA 4WZ2A 2YU4A 4YBSA 2LGLA 5AITA 5TRBA 2VPGA 3NG2A 4GB0A 4S3OC 1WGMA 2YQLA 3DPLR 4BBQA 3GL6A 2L80A 2G45A 2VPDA 5DINA 4AYCA 2JRJA 2AN6A 4GNEA 2YURA 2MD8C 3DQVR 1VFYA 1Z6UA 1Z2QA 4YABA 5J3XA 5B77A 3N9NA 1MM3A 2PNXA 2G43A 4FK5A 3FL2A 4AUQB 5G05B 2K1JA 4QF2A 2KFTA 5JG6A 1WEPA 2K4DA 2LGGA 4UP0A 2MA6A 4B7YC 2E6RA 2ECIA 1JM7A 2EA6A 2LQ6A 2M85A 2KGGA 4CA1A 4A4BA 4AYCB 2RSDA 4LJNA 4WA6A 5FEYA 5C11A 1E4UA 4BHWA 5LKZA 2MNYA 3N9LA 3C6WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VYX A;  4YAD A;  3LRQ A;  2YSM A;  4MSX A;  2CSZ A;  2ECV A;  2Y1M A;  1WE9 A;  2EOD A;  1VD4 A;  1JOC A;  2KRE A;  4ZDT A;  3ZVZ B;  3U5O A;  2JMJ A;  3L1X A;  5B76 A;  2YSJ A;  3LQJ A;  2VJF B;  4S3O B;  4PTB A;  5TBN A;  2HYE D;  3RTR B;  2FUI A;  3QZV A;  4YBM A;  3M62 A;  4V3L C;  4I7B A;  3U5M A;  3L1Z B;  2C2V S;  3VK6 A;  2I50 A;  3GV4 A;  2KU3 A;  2CT2 A;  4R7E A;  1WEE A;  2F6J A;  3ASL A;  5DKA A;  2L5U A;  4L58 A;  1XWH A;  4C9Z A;  2KWJ A;  2YHN A;  3N9O A;  5KH3 A;  1WEM A;  3V43 A;  1WEO A;  4AVX A;  4TKP B;  4FO9 A;  2YRE A;  2KGI A;  2VP7 A;  2K17 A;  2MUM A;  5TDW A;  2C2L A;  3KV5 A;  3HCU A;  2KWK A;  1F62 A;  3PUR A;  2LRI C;  2YUC A;  3ZPV 1;  5TAB A;  4O64 A;  2VPE A;  5B79 A;  3O7A A;  2G6Q A;  2M3H A;  5LKT A;  2YT5 A;  4A4C A;  3M99 A;  4LAD B;  3EB6 A;  1X4J A;  3N9M A;  4QF3 A;  1WEN A;  1RMD A;  3KQI A;  5KH9 A;  3ZYQ A;  2LGV A;  5B8D A;  2L43 A;  2VJF A;  2ZET C;  3SOW A;  5I3L A;  5TDR A;  3ZNI A;  5H1T A;  2JMD A;  3O33 A;  5H1V A;  2EGP A;  1T1H A;  2XB1 A;  2F42 A;  5B75 A;  4WZ0 A;  3LQI A;  3U5N A;  4R8P K;  1X4I A;  3O34 A;  2KYU A;  2K16 A;  1DVP A;  3O70 A;  4I7D A;  2KIZ A;  2DX8 A;  1FBV A;  1WES A;  4W4U A;  2MNZ A;  2KWO A;  2HDP A;  4GNG A;  4GND A;  5FER A;  4ZQL A;  4X3G A;  3ZTG A;  4PPE A;  1U6G B;  4AP4 A;  3ZPV E;  3PHD A;  1G25 A;  3O37 A;  2OXQ C;  2LN0 A;  3HCS A;  3HCT A;  1MM2 A;  3N9Q A;  4IC2 A;  4YAX A;  1Z60 A;  3SOU A;  4F52 B;  5D1M B;  4Q6F A;  2LDR A;  5LKU A;  5D1K B;  2LGK A;  2KWN A;  2CSY A;  4XI1 A;  4N3W A;  5FB0 A;  4V3K C;  3SOX A;  5G04 B;  5G0F A;  3C5K A;  2VNF A;  4GNF A;  2Y43 A;  2IDA A;  2JMI A;  2ECJ A;  2ECW A;  3T6R A;  2L0B A;  3SHB A;  4A49 A;  2LV9 A;  2QJ0 A;  4WZ3 B;  2MIQ A;  5H9M A;  1WEQ A;  1N87 A;  3L11 A;  2YHO A;  1ZBD B;  2H0D A;  4NN2 A;  1LDJ B;  2BAY A;  1WEV A;  2XEU A;  4B86 C;  2ECT A;  3KV6 A;  4N4F A;  4L7X A;  4LLB A;  2KE1 A;  3RPG B;  4YAT A;  3KNV A;  2RI7 A;  2YQM A;  2VJE B;  2CKL A;  2YYR A;  3N9P A;  3O36 A;  4FJC A;  3IHP A;  5AIU A;  4UP5 A;  2H0D B;  2MT5 A;  5LCW B;  4MVT A;  3T7L A;  2VPB A;  2MA5 A;  1WEW A;  2YW8 A;  4I7C A;  5FB1 A;  1BOR A;  2LXP C;  2FUU A;  5D1L B;  3I2D A;  4LKA A;  3PUQ A;  1CHC A;  2MD7 B;  2M1R A;  2ECN A;  2CKL B;  3U5P A;  3RPG C;  3O35 A;  1LDK C;  2L75 A;  3LQH A;  1WIL A;  4FIP A;  4IC3 A;  4YC9 A;  3MHH A;  2F6N A;  2PUY A;  4UI9 B;  5C13 A;  1JM7 B;  2QIZ A;  1K2F A;  1WEU A;  4CCG X;  3HTK C;  2Y1N A;  2M6M A;  5KH7 A;  2FSA A;  2QIC A;  2LXH C;  2KR4 A;  3EB5 A;  2ECG A;  3M63 A;  2E6S A;  5LKX A;  5EYA F;  4P5O B;  1WFK A;  5H1U A;  2UZG A;  2NAA A;  2VJE A;  1X4U A;  1FP0 A;  4LK9 A;  1WIM A;  1HYI A;  3ZVY A;  5B78 A;  1IYM A;  4R2Y A;  1HYJ A;  2D8S A;  4YBT A;  4A0C D;  1V87 A;  4ZUX U;  3MHS A;  4WZ2 A;  2YU4 A;  4YBS A;  2LGL A;  5AIT A;  5TRB A;  2VPG A;  3NG2 A;  4GB0 A;  4S3O C;  1WGM A;  2YQL A;  3DPL R;  4BBQ A;  3GL6 A;  2L80 A;  2G45 A;  2VPD A;  5DIN A;  4AYC A;  2JRJ A;  2AN6 A;  4GNE A;  2YUR A;  2MD8 C;  3DQV R;  1VFY A;  1Z6U A;  1Z2Q A;  4YAB A;  5J3X A;  5B77 A;  3N9N A;  1MM3 A;  2PNX A;  2G43 A;  4FK5 A;  3FL2 A;  4AUQ B;  5G05 B;  2K1J A;  4QF2 A;  2KFT A;  5JG6 A;  1WEP A;  2K4D A;  2LGG A;  4UP0 A;  2MA6 A;  4B7Y C;  2E6R A;  2ECI A;  1JM7 A;  2EA6 A;  2LQ6 A;  2M85 A;  2KGG A;  4CA1 A;  4A4B A;  4AYC B;  2RSD A;  4LJN A;  4WA6 A;  5FEY A;  5C11 A;  1E4U A;  4BHW A;  5LKZ A;  2MNY A;  3N9L A;  3C6W A; 
#chains in the Genus database with same CATH topology
 2B0O E;  1VYX A;  4YAD A;  3LRQ A;  2YSM A;  4MSX A;  2CSZ A;  2XP0 A;  2ECV A;  2Y1M A;  1WE9 A;  2EOD A;  1VD4 A;  1JOC A;  2KRE A;  4ZDT A;  3ZVZ B;  3U5O A;  2JMJ A;  3L1X A;  3DWD A;  2YSJ A;  5B76 A;  3LQJ A;  4H9D A;  2VJF B;  4S3O B;  4PTB A;  5TBN A;  2YVR A;  4Z0O A;  2HYE D;  3RTR B;  2FUI A;  3QZV A;  4YBM A;  3M62 A;  4V3L C;  4I7B A;  3U5M A;  3L1Z B;  2C2V S;  3VK6 A;  2I50 A;  3GV4 A;  2KU3 A;  2CT2 A;  4R7E A;  1WEE A;  2F6J A;  3ASL A;  5DKA A;  2L5U A;  4L58 A;  1XWH A;  4C9Z A;  2KWJ A;  2YHN A;  3N9O A;  5KH3 A;  1WEM A;  3V43 A;  1WEO A;  4AVX A;  4TKP B;  4FO9 A;  2XOC A;  2YRE A;  2KGI A;  2VP7 A;  2K17 A;  2MUM A;  5TDW A;  2C2L A;  3KV5 A;  3HCU A;  2KWK A;  1F62 A;  3PUR A;  2EGM A;  2LRI C;  4OGE A;  2YUC A;  3ZPV 1;  3E2D A;  5TAB A;  4O64 A;  2VPE A;  5B79 A;  3O7A A;  2G6Q A;  2M3H A;  5LKT A;  2YT5 A;  4A4C A;  3M99 A;  4LAD B;  2RR4 A;  3EB6 A;  1X4J A;  3N9M A;  4QF3 A;  1WEN A;  1RMD A;  5SVX A;  3KQI A;  5KH9 A;  3ZYQ A;  2LGV A;  5B8D A;  2L43 A;  2VJF A;  2CRW A;  2ZET C;  3SOW A;  5I3L A;  5TDR A;  3ZNI A;  5H1T A;  2JMD A;  3O33 A;  5H1V A;  2EGP A;  1T1H A;  2XB1 A;  2XOZ A;  2F42 A;  5B75 A;  4WZ0 A;  3LQI A;  3U5N A;  4R8P K;  1X4I A;  3O34 A;  2KYU A;  3H7H A;  3KDE C;  2K16 A;  2JUN A;  1DVP A;  3O70 A;  4I7D A;  3LDY A;  2KIZ A;  2DX8 A;  1FBV A;  1WES A;  4W4U A;  2MNZ A;  3FAO A;  2KWO A;  2HDP A;  4GNG A;  4GND A;  5FER A;  4ZQL A;  4X3G A;  3ZTG A;  5SVY A;  4PPE A;  1U6G B;  4AP4 A;  3ZPV E;  3PHD A;  1G25 A;  3O37 A;  2OXQ C;  2LN0 A;  3HCS A;  3HCT A;  1MM2 A;  4O62 A;  3N9Q A;  4IC2 A;  4YAX A;  1Z60 A;  3SOU A;  4F52 B;  3FJU B;  2D8U A;  2JM3 A;  5D1M B;  4Q6F A;  2LDR A;  4Z0R A;  5LKU A;  5D1K B;  2LGK A;  2KWN A;  2CSY A;  4XI1 A;  4N3W A;  5FB0 A;  4V3K C;  3SOX A;  5G04 B;  5G0F A;  3C5K A;  2VNF A;  4GNF A;  2Y43 A;  2IDA A;  2JMI A;  2CRR A;  2ECJ A;  2ECW A;  3T6R A;  2L0B A;  2KKY A;  3SHB A;  4A49 A;  2LV9 A;  2QJ0 A;  4WZ3 B;  2MIQ A;  5H9M A;  1WEQ A;  1N87 A;  3L11 A;  2YHO A;  3LJU X;  3T9K A;  1ZBD B;  2H0D A;  1DCQ A;  4NN2 A;  1LDJ B;  2BAY A;  3Q1D A;  1WEV A;  3FEH A;  2XEU A;  4B86 C;  2ECT A;  3KV6 A;  4N4F A;  4L7X A;  4LLB A;  2KE1 A;  3RPG B;  2DSM A;  3KNV A;  4YAT A;  5K3Q A;  2RI7 A;  2YQM A;  2VJE B;  4F1P A;  2CON A;  2CKL A;  2YYR A;  3O47 A;  2FFW A;  3N9P A;  3O36 A;  4FJC A;  4QQ4 A;  3IHP A;  5AIU A;  2XOY A;  4UP5 A;  2DJA A;  2H0D B;  2MT5 A;  5LCW B;  4MVT A;  3T7L A;  2VPB A;  2MA5 A;  1WEW A;  2YW8 A;  4I7C A;  5FB1 A;  1BOR A;  2LXP C;  2FUU A;  5D1L B;  3I2D A;  4LKA A;  3PUQ A;  3FM8 C;  1CHC A;  2MD7 B;  2M1R A;  2LAU A;  2ECN A;  2CKL B;  3U5P A;  3RPG C;  3O35 A;  1LDK C;  2L75 A;  3LQH A;  1WIL A;  3SUB A;  4FIP A;  4IC3 A;  4YC9 A;  3MHH A;  2F6N A;  2PUY A;  4UI9 B;  5C13 A;  1JM7 B;  2QIZ A;  1K2F A;  1WEU A;  4CCG X;  2E61 A;  3HTK C;  3DDT A;  3FAN A;  2EXU A;  3LVQ E;  2Y1N A;  3JUE A;  2M6M A;  5KH7 A;  2FSA A;  2QIC A;  2LXH C;  2KR4 A;  1MBM A;  3EB5 A;  2ECG A;  3M63 A;  2E6S A;  2M13 A;  5LKX A;  2L7P A;  5EYA F;  4P5O B;  1WFK A;  5H1U A;  2UZG A;  2NAA A;  2OWA A;  2VJE A;  1X4U A;  1FP0 A;  4LK9 A;  1WIM A;  1HYI A;  3ZVY A;  5B78 A;  1IYM A;  4R2Y A;  2FD4 A;  1HYJ A;  2D8S A;  4YBT A;  4A0C D;  1V87 A;  4ZUX U;  3LVR E;  3MHS A;  4WZ2 A;  2YU4 A;  4YBS A;  2LGL A;  5AIT A;  5TRB A;  2CSV A;  2VPG A;  3NG2 A;  3M7K A;  4GB0 A;  4S3O C;  1WGM A;  2YQL A;  3DPL R;  4BBQ A;  3PLW A;  3MDB C;  3GL6 A;  2L80 A;  2G45 A;  2VPD A;  5DIN A;  4AYC A;  2KKX A;  2JRJ A;  2AN6 A;  4GNE A;  2YUR A;  2MD8 C;  3DQV R;  1VFY A;  4OGC A;  1Z6U A;  1Z2Q A;  4YAB A;  5J3X A;  5B77 A;  3N9N A;  1MM3 A;  2PNX A;  2G43 A;  4FK5 A;  3FL2 A;  4AUQ B;  5G05 B;  2K1J A;  2IQJ A;  4QF2 A;  5SVI A;  2KFT A;  5JG6 A;  1WEP A;  2K4D A;  2LGG A;  4UP0 A;  2MA6 A;  4B7Y C;  2E6R A;  2ECI A;  1JM7 A;  2EA6 A;  2P57 A;  2LQ6 A;  2M85 A;  2KGG A;  4CA1 A;  4A4B A;  4AYC B;  2RSD A;  4LJN A;  4WA6 A;  2MKE A;  5FEY A;  5C11 A;  1E4U A;  4BHW A;  5LKZ A;  2MNY A;  5SVI B;  3N9L A;  3C6W A; 
#chains in the Genus database with same CATH homology
 1VYX A;  4YAD A;  3LRQ A;  2YSM A;  4MSX A;  2CSZ A;  2ECV A;  2Y1M A;  1WE9 A;  2EOD A;  1VD4 A;  1JOC A;  2KRE A;  4ZDT A;  3ZVZ B;  3U5O A;  2JMJ A;  3L1X A;  5B76 A;  2YSJ A;  3LQJ A;  2VJF B;  4S3O B;  4PTB A;  5TBN A;  2HYE D;  3RTR B;  2FUI A;  3QZV A;  4YBM A;  3M62 A;  4V3L C;  4I7B A;  3U5M A;  3L1Z B;  2C2V S;  3VK6 A;  2I50 A;  3GV4 A;  2KU3 A;  2CT2 A;  4R7E A;  1WEE A;  2F6J A;  3ASL A;  5DKA A;  2L5U A;  4L58 A;  1XWH A;  4C9Z A;  2KWJ A;  2YHN A;  3N9O A;  5KH3 A;  1WEM A;  3V43 A;  1WEO A;  4AVX A;  4TKP B;  4FO9 A;  2YRE A;  2KGI A;  2VP7 A;  2K17 A;  2MUM A;  5TDW A;  2C2L A;  3KV5 A;  3HCU A;  2KWK A;  1F62 A;  3PUR A;  2LRI C;  2YUC A;  3ZPV 1;  5TAB A;  4O64 A;  2VPE A;  5B79 A;  3O7A A;  2G6Q A;  2M3H A;  5LKT A;  2YT5 A;  4A4C A;  3M99 A;  4LAD B;  3EB6 A;  1X4J A;  3N9M A;  4QF3 A;  1WEN A;  1RMD A;  3KQI A;  5KH9 A;  3ZYQ A;  2LGV A;  5B8D A;  2L43 A;  2VJF A;  2ZET C;  3SOW A;  5I3L A;  5TDR A;  3ZNI A;  5H1T A;  2JMD A;  3O33 A;  5H1V A;  2EGP A;  1T1H A;  2XB1 A;  2F42 A;  5B75 A;  4WZ0 A;  3LQI A;  3U5N A;  4R8P K;  1X4I A;  3O34 A;  2KYU A;  2K16 A;  1DVP A;  3O70 A;  4I7D A;  2KIZ A;  2DX8 A;  1FBV A;  1WES A;  4W4U A;  2MNZ A;  2KWO A;  2HDP A;  4GNG A;  4GND A;  5FER A;  4ZQL A;  4X3G A;  3ZTG A;  4PPE A;  1U6G B;  4AP4 A;  3ZPV E;  3PHD A;  1G25 A;  3O37 A;  2OXQ C;  2LN0 A;  3HCS A;  3HCT A;  1MM2 A;  3N9Q A;  4IC2 A;  4YAX A;  1Z60 A;  3SOU A;  4F52 B;  5D1M B;  4Q6F A;  2LDR A;  5LKU A;  5D1K B;  2LGK A;  2KWN A;  2CSY A;  4XI1 A;  4N3W A;  5FB0 A;  4V3K C;  3SOX A;  5G04 B;  5G0F A;  3C5K A;  2VNF A;  4GNF A;  2Y43 A;  2IDA A;  2JMI A;  2ECJ A;  2ECW A;  3T6R A;  2L0B A;  3SHB A;  4A49 A;  2LV9 A;  2QJ0 A;  4WZ3 B;  2MIQ A;  5H9M A;  1WEQ A;  1N87 A;  3L11 A;  2YHO A;  1ZBD B;  2H0D A;  4NN2 A;  1LDJ B;  2BAY A;  1WEV A;  2XEU A;  4B86 C;  2ECT A;  3KV6 A;  4N4F A;  4L7X A;  4LLB A;  2KE1 A;  3RPG B;  4YAT A;  3KNV A;  2RI7 A;  2YQM A;  2VJE B;  2CKL A;  2YYR A;  3N9P A;  3O36 A;  4FJC A;  3IHP A;  5AIU A;  4UP5 A;  2H0D B;  2MT5 A;  5LCW B;  4MVT A;  3T7L A;  2VPB A;  2MA5 A;  1WEW A;  2YW8 A;  4I7C A;  5FB1 A;  1BOR A;  2LXP C;  2FUU A;  5D1L B;  3I2D A;  4LKA A;  3PUQ A;  1CHC A;  2MD7 B;  2M1R A;  2ECN A;  2CKL B;  3U5P A;  3RPG C;  3O35 A;  1LDK C;  2L75 A;  3LQH A;  1WIL A;  4FIP A;  4IC3 A;  4YC9 A;  3MHH A;  2F6N A;  2PUY A;  4UI9 B;  5C13 A;  1JM7 B;  2QIZ A;  1K2F A;  1WEU A;  4CCG X;  3HTK C;  2Y1N A;  2M6M A;  5KH7 A;  2FSA A;  2QIC A;  2LXH C;  2KR4 A;  3EB5 A;  2ECG A;  3M63 A;  2E6S A;  5LKX A;  5EYA F;  4P5O B;  1WFK A;  5H1U A;  2UZG A;  2NAA A;  2VJE A;  1X4U A;  1FP0 A;  4LK9 A;  1WIM A;  1HYI A;  3ZVY A;  5B78 A;  1IYM A;  4R2Y A;  1HYJ A;  2D8S A;  4YBT A;  4A0C D;  1V87 A;  4ZUX U;  3MHS A;  4WZ2 A;  2YU4 A;  4YBS A;  2LGL A;  5AIT A;  5TRB A;  2VPG A;  3NG2 A;  4GB0 A;  4S3O C;  1WGM A;  2YQL A;  3DPL R;  4BBQ A;  3GL6 A;  2L80 A;  2G45 A;  2VPD A;  5DIN A;  4AYC A;  2JRJ A;  2AN6 A;  4GNE A;  2YUR A;  2MD8 C;  3DQV R;  1VFY A;  1Z6U A;  1Z2Q A;  4YAB A;  5J3X A;  5B77 A;  3N9N A;  1MM3 A;  2PNX A;  2G43 A;  4FK5 A;  3FL2 A;  4AUQ B;  5G05 B;  2K1J A;  4QF2 A;  2KFT A;  5JG6 A;  1WEP A;  2K4D A;  2LGG A;  4UP0 A;  2MA6 A;  4B7Y C;  2E6R A;  2ECI A;  1JM7 A;  2EA6 A;  2LQ6 A;  2M85 A;  2KGG A;  4CA1 A;  4A4B A;  4AYC B;  2RSD A;  4LJN A;  4WA6 A;  5FEY A;  5C11 A;  1E4U A;  4BHW A;  5LKZ A;  2MNY A;  3N9L A;  3C6W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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