2VJFB

Crystal structure of the mdm2-mdmx ring domain heterodimer
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
63
structure length
63
Chain Sequence
EDCQNLLKPCSLCEKRPRDGNIIHGRTGHLVTCFHCARRLKKAGASCPICKKEIQLVIKVFIA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the Mdm2/Mdmx Ring Domain Heterodimer Reveals Dimerization is Required for Their Ubiquitylation in Trans.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE MDM2
total genus 13
structure length 63
sequence length 63
chains with identical sequence D
ec nomenclature
pdb deposition date 2007-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF13920 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.10 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Zinc/RING finger domain, C3HC4 (zinc finger) 2vjfB00
2YUCA 4LADB 2VJFB 2ZETC 5TDRA 2JMDA 5B77A 2H0DB 2VPBA 2VPGA 4GNGA 2L75A 5LKXA 1WEMA 4I7DA 4A49A 2K1JA 2K16A 1IYMA 1WENA 4W4UA 4R2YA 1WEWA 4IC2A 2KFTA 2QICA 3O35A 3NG2A 4GNDA 4AYCB 5LCWB 2K4DA 3N9NA 5LKZA 2MIQA 1BORA 2G45A 2LDRA 3SOWA 2Y1MA 2M85A 5G04B 3L1XA 4X3GA 2MNYA 5H1VA 2C2VS 2LV9A 3SOXA 1FBVA 2YSJA 1Z2QA 1JM7B 2EA6A 3HCTA 2KWKA 5B78A 4FIPA 4YABA 4YAXA 2HDPA 5DINA 2ECIA 2LN0A 1V87A 2M6MA 4QF2A 4N4FA 5TBNA 4ZDTA 3U5MA 5TABA 3KV5A 2Y43A 2G6QA 2KGGA 3ZPVE 2MD8C 3ZVZB 1LDKC 1WIMA 5D1MB 2KWNA 2MD7B 5FB0A 2VNFA 2VPDA 2KU3A 1JOCA 3GV4A 5B75A 3MHHA 1WGMA 5TDWA 5I3LA 4IC3A 5AIUA 3LRQA 3ASLA 2VJEA 2VJEB 4QF3A 5H9MA 2FUUA 2CKLA 1LDJB 3MHSA 2LGKA 2EODA 3V43A 3EB5A 3C6WA 1T1HA 1WEEA 2JMJA 4R7EA 4A0CD 4UP0A 2FSAA 1RMDA 3N9MA 4MVTA 1Z60A 3HCUA 2VP7A 4ZUXU 3U5OA 2XEUA 2ECJA 2MUMA 2Y1NA 2KWOA 3M62A 3ZNIA 4I7CA 1MM3A 3O70A 2KR4A 4UI9B 4YADA 1WEVA 4PPEA 2L5UA 4YBTA 4ZQLA 4P5OB 1MM2A 2PUYA 3SHBA 3IHPA 4YBSA 1FP0A 4C9ZA 3T6RA 1WESA 2BAYA 5FEYA 2K17A 5C11A 3PUQA 2JRJA 2PNXA 1K2FA 2L43A 2YHOA 2ECGA 2KGIA 3M63A 1WE9A 3LQJA 2HYED 2E6SA 4Q6FA 2YU4A 4YC9A 3RPGB 1X4UA 2YSMA 3ZVYA 1F62A 3DPLR 3O34A 4MSXA 4A4CA 3O7AA 5J3XA 1G25A 3T7LA 5KH7A 2F42A 4LLBA 1DVPA 1N87A 5JG6A 3KV6A 4NN2A 2XB1A 2FUIA 5C13A 4S3OB 4A4BA 3N9QA 2KWJA 4WZ2A 1VD4A 1WEPA 3U5NA 4V3KC 4LKAA 2DX8A 3RPGC 4GNFA 2LGLA 3N9LA 2OXQC 2VPEA 3C5KA 1HYIA 3LQIA 2CKLB 2QJ0A 5G05B 2MNZA 1X4IA 2QIZA 5AITA 2KE1A 3O37A 4O64A 4WA6A 3KQIA 5EYAF 4WZ0A 5B8DA 1WFKA 2NAAA 3I2DA 5DKAA 3FL2A 4GNEA 4N3WA 2KYUA 4TKPB 2MT5A 2YQLA 4BHWA 3PURA 4L58A 2YW8A 5KH3A 2KREA 3SOUA 3U5PA 4S3OC 3EB6A 4YBMA 3L1ZB 5LKUA 2CSZA 4CCGX 2YHNA 4BBQA 2VJFA 3DQVR 3QZVA 2H0DA 1U6GB 1CHCA 2ECVA 1HYJA 2YURA 2ECWA 3KNVA 5G0FA 4R8PK 2D8SA 2F6NA 4YATA 5H1UA 4B7YC 1VFYA 1ZBDB 4L7XA 4FO9A 5H1TA 4WZ3B 4AVXA 4LK9A 3O36A 4AYCA 5D1KB 5FERA 3ZPV1 4PTBA 5B79A 5LKTA 4FK5A 3N9PA 2LQ6A 2M1RA 4F52B 2MA5A 2YQMA 4CA1A 2L0BA 4B86C 2LXPC 2MA6A 2G43A 2YYRA 4LJNA 2ECTA 2F6JA 1XWHA 1E4UA 1WEOA 2I50A 3ZTGA 2LGVA 1JM7A 1X4JA 2LRIC 2CSYA 4V3LC 1Z6UA 2CT2A 3HCSA 5D1LB 4AP4A 4AUQB 2EGPA 2IDAA 1WEQA 4FJCA 4GB0A 3ZYQA 1VYXA 3LQHA 2JMIA 5KH9A 2E6RA 2YT5A 3GL6A 1WILA 2AN6A 2L80A 1WEUA 2ECNA 2KIZA 5B76A 3M99A 3L11A 3VK6A 3N9OA 2UZGA 4XI1A 4I7BA 2LXHC 5TRBA 2M3HA 2RI7A 2C2LA 3HTKC 3PHDA 2YREA 3RTRB 2RSDA 4UP5A 3O33A 5FB1A 2LGGA
chains in the Genus database with same CATH superfamily
2KKYA 2XP0A 2YUCA 4LADB 2VJFB 2ZETC 2XOCA 5TDRA 2JMDA 5B77A 2H0DB 2VPBA 2VPGA 4GNGA 5SVIB 2L75A 5LKXA 1WEMA 4I7DA 4A49A 2K1JA 2K16A 1IYMA 1WENA 4W4UA 4R2YA 2P57A 1WEWA 4IC2A 2KFTA 2QICA 3O35A 3NG2A 4GNDA 4AYCB 2K4DA 3N9NA 5LCWB 3PLWA 5LKZA 2MIQA 1BORA 2G45A 2LDRA 3SOWA 2Y1MA 2M85A 5G04B 3FAOA 3L1XA 4X3GA 2MNYA 4F1PA 5H1VA 2C2VS 1DCQA 3MDBC 2LV9A 3SOXA 1FBVA 2YSJA 1Z2QA 1JM7B 2EA6A 3HCTA 2KWKA 5B78A 4FIPA 4YABA 4YAXA 2HDPA 5DINA 2ECIA 2LN0A 1V87A 2M6MA 4QF2A 4N4FA 3Q1DA 5TBNA 2JM3A 2MKEA 2XOZA 4ZDTA 5SVXA 3U5MA 5TABA 4QQ4A 2DSMA 3KV5A 2Y43A 2G6QA 2KGGA 3ZPVE 2MD8C 3ZVZB 1LDKC 1WIMA 5D1MB 2KWNA 2MD7B 3T9KA 5FB0A 2VNFA 2VPDA 2KU3A 1JOCA 3GV4A 5B75A 3MHHA 1WGMA 5TDWA 5I3LA 4IC3A 5AIUA 3LRQA 3ASLA 2VJEA 2VJEB 2E61A 4QF3A 5H9MA 2FUUA 2CKLA 1LDJB 3MHSA 2LGKA 2DJAA 2EODA 3V43A 3EB5A 3C6WA 1T1HA 1WEEA 2JMJA 4R7EA 4A0CD 4UP0A 2FSAA 1RMDA 3N9MA 4MVTA 1Z60A 3HCUA 2VP7A 4ZUXU 3U5OA 2XEUA 2ECJA 2MUMA 2Y1NA 2M13A 2KWOA 3M62A 3ZNIA 4I7CA 1MM3A 3E2DA 3O70A 2KR4A 3SUBA 2CONA 4UI9B 3H7HA 2CSVA 4YADA 1WEVA 4PPEA 2L5UA 4YBTA 4ZQLA 4P5OB 1MM2A 2PUYA 3SHBA 3IHPA 4YBSA 3KDEC 1FP0A 4C9ZA 3T6RA 1WESA 2BAYA 5FEYA 2K17A 5C11A 3PUQA 2JRJA 2PNXA 1K2FA 2L43A 2YHOA 2ECGA 2KGIA 3M63A 3LDYA 1WE9A 3LQJA 2HYED 2LAUA 2E6SA 4Q6FA 2YU4A 4YC9A 3RPGB 1X4UA 2YSMA 2FFWA 3ZVYA 3LJUX 1F62A 3DPLR 3O34A 3O47A 4Z0OA 4MSXA 4A4CA 3O7AA 5J3XA 1G25A 3T7LA 5KH7A 2F42A 4LLBA 1DVPA 1N87A 5JG6A 1MBMA 3FANA 3KV6A 4NN2A 2XB1A 2FUIA 2IQJA 5C13A 4S3OB 4A4BA 3N9QA 2KWJA 4WZ2A 1VD4A 2CRWA 1WEPA 3U5NA 4Z0RA 4V3KC 4LKAA 2DX8A 3DWDA 4GNFA 2LGLA 3RPGC 3N9LA 2OXQC 2VPEA 3C5KA 1HYIA 3LQIA 2CKLB 2QJ0A 5G05B 2MNZA 1X4IA 2QIZA 5AITA 2EXUA 2KE1A 3O37A 4O64A 4WA6A 3KQIA 5EYAF 4WZ0A 5B8DA 1WFKA 2NAAA 3I2DA 5DKAA 3FL2A 4GNEA 4N3WA 2KYUA 3FJUB 4TKPB 2MT5A 4OGEA 2YQLA 4BHWA 3PURA 4L58A 2YW8A 5KH3A 2KREA 3SOUA 3U5PA 4S3OC 3EB6A 4YBMA 3L1ZB 5LKUA 4OGCA 2CSZA 4CCGX 2YHNA 4BBQA 2VJFA 3DQVR 3QZVA 2H0DA 1U6GB 5SVIA 1CHCA 2ECVA 1HYJA 2YURA 2ECWA 2XOYA 3KNVA 2D8UA 5G0FA 2FD4A 4R8PK 2D8SA 2F6NA 4YATA 3M7KA 5H1UA 3DDTA 4B7YC 1VFYA 2CRRA 1ZBDB 4L7XA 4FO9A 5H1TA 4O62A 4WZ3B 4AVXA 4LK9A 3O36A 4AYCA 5D1KB 5FERA 3ZPV1 2JUNA 4PTBA 5B79A 5LKTA 4FK5A 3N9PA 5K3QA 2LQ6A 2M1RA 4F52B 2MA5A 2YQMA 4CA1A 2L0BA 3FM8C 2L7PA 4B86C 2LXPC 2MA6A 2G43A 2YYRA 4LJNA 2ECTA 2F6JA 1XWHA 1E4UA 1WEOA 2I50A 3ZTGA 5SVYA 2RR4A 2LGVA 1JM7A 1X4JA 2LRIC 2CSYA 3LVRE 4V3LC 1Z6UA 4H9DA 2CT2A 3HCSA 3FEHA 5D1LB 4AP4A 2EGMA 2OWAA 4AUQB 2EGPA 2IDAA 1WEQA 4FJCA 4GB0A 3ZYQA 1VYXA 3LQHA 2JMIA 5KH9A 2E6RA 2YT5A 3JUEA 3GL6A 1WILA 2AN6A 2L80A 1WEUA 2B0OE 2ECNA 2KIZA 2YVRA 5B76A 3M99A 3L11A 3VK6A 3N9OA 2UZGA 4XI1A 4I7BA 2LXHC 5TRBA 2M3HA 2RI7A 2C2LA 3HTKC 3PHDA 2YREA 3RTRB 2RSDA 2KKXA 4UP5A 3O33A 5FB1A 3LVQE 2LGGA
chains in the Genus database with same CATH topology
2YUCA 4LADB 2VJFB 2ZETC 5TDRA 2JMDA 5B77A 2H0DB 2VPBA 2VPGA 4GNGA 2L75A 5LKXA 1WEMA 4I7DA 4A49A 2K1JA 2K16A 1IYMA 1WENA 4W4UA 4R2YA 1WEWA 4IC2A 2KFTA 2QICA 3O35A 3NG2A 4GNDA 4AYCB 5LCWB 2K4DA 3N9NA 5LKZA 2MIQA 1BORA 2G45A 2LDRA 3SOWA 2Y1MA 2M85A 5G04B 3L1XA 4X3GA 2MNYA 5H1VA 2C2VS 2LV9A 3SOXA 1FBVA 2YSJA 1Z2QA 1JM7B 2EA6A 3HCTA 2KWKA 5B78A 4FIPA 4YABA 4YAXA 2HDPA 5DINA 2ECIA 2LN0A 1V87A 2M6MA 4QF2A 4N4FA 5TBNA 4ZDTA 3U5MA 5TABA 3KV5A 2Y43A 2G6QA 2KGGA 3ZPVE 2MD8C 3ZVZB 1LDKC 1WIMA 5D1MB 2KWNA 2MD7B 5FB0A 2VNFA 2VPDA 2KU3A 1JOCA 3GV4A 5B75A 3MHHA 1WGMA 5TDWA 5I3LA 4IC3A 5AIUA 3LRQA 3ASLA 2VJEA 2VJEB 4QF3A 5H9MA 2FUUA 2CKLA 1LDJB 3MHSA 2LGKA 2EODA 3V43A 3EB5A 3C6WA 1T1HA 1WEEA 2JMJA 4R7EA 4A0CD 4UP0A 2FSAA 1RMDA 3N9MA 4MVTA 1Z60A 3HCUA 2VP7A 4ZUXU 3U5OA 2XEUA 2ECJA 2MUMA 2Y1NA 2KWOA 3M62A 3ZNIA 4I7CA 1MM3A 3O70A 2KR4A 4UI9B 4YADA 1WEVA 4PPEA 2L5UA 4YBTA 4ZQLA 4P5OB 1MM2A 2PUYA 3SHBA 3IHPA 4YBSA 1FP0A 4C9ZA 3T6RA 1WESA 2BAYA 5FEYA 2K17A 5C11A 3PUQA 2JRJA 2PNXA 1K2FA 2L43A 2YHOA 2ECGA 2KGIA 3M63A 1WE9A 3LQJA 2HYED 2E6SA 4Q6FA 2YU4A 4YC9A 3RPGB 1X4UA 2YSMA 3ZVYA 1F62A 3DPLR 3O34A 4MSXA 4A4CA 3O7AA 5J3XA 1G25A 3T7LA 5KH7A 2F42A 4LLBA 1DVPA 1N87A 5JG6A 3KV6A 4NN2A 2XB1A 2FUIA 5C13A 4S3OB 4A4BA 3N9QA 2KWJA 4WZ2A 1VD4A 1WEPA 3U5NA 4V3KC 4LKAA 2DX8A 3RPGC 4GNFA 2LGLA 3N9LA 2OXQC 2VPEA 3C5KA 1HYIA 3LQIA 2CKLB 2QJ0A 5G05B 2MNZA 1X4IA 2QIZA 5AITA 2KE1A 3O37A 4O64A 4WA6A 3KQIA 5EYAF 4WZ0A 5B8DA 1WFKA 2NAAA 3I2DA 5DKAA 3FL2A 4GNEA 4N3WA 2KYUA 4TKPB 2MT5A 2YQLA 4BHWA 3PURA 4L58A 2YW8A 5KH3A 2KREA 3SOUA 3U5PA 4S3OC 3EB6A 4YBMA 3L1ZB 5LKUA 2CSZA 4CCGX 2YHNA 4BBQA 2VJFA 3DQVR 3QZVA 2H0DA 1U6GB 1CHCA 2ECVA 1HYJA 2YURA 2ECWA 3KNVA 5G0FA 4R8PK 2D8SA 2F6NA 4YATA 5H1UA 4B7YC 1VFYA 1ZBDB 4L7XA 4FO9A 5H1TA 4WZ3B 4AVXA 4LK9A 3O36A 4AYCA 5D1KB 5FERA 3ZPV1 4PTBA 5B79A 5LKTA 4FK5A 3N9PA 2LQ6A 2M1RA 4F52B 2MA5A 2YQMA 4CA1A 2L0BA 4B86C 2LXPC 2MA6A 2G43A 2YYRA 4LJNA 2ECTA 2F6JA 1XWHA 1E4UA 1WEOA 2I50A 3ZTGA 2LGVA 1JM7A 1X4JA 2LRIC 2CSYA 4V3LC 1Z6UA 2CT2A 3HCSA 5D1LB 4AP4A 4AUQB 2EGPA 2IDAA 1WEQA 4FJCA 4GB0A 3ZYQA 1VYXA 3LQHA 2JMIA 5KH9A 2E6RA 2YT5A 3GL6A 1WILA 2AN6A 2L80A 1WEUA 2ECNA 2KIZA 5B76A 3M99A 3L11A 3VK6A 3N9OA 2UZGA 4XI1A 4I7BA 2LXHC 5TRBA 2M3HA 2RI7A 2C2LA 3HTKC 3PHDA 2YREA 3RTRB 2RSDA 4UP5A 3O33A 5FB1A 2LGGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YUC A;  4LAD B;  2VJF B;  2ZET C;  5TDR A;  2JMD A;  5B77 A;  2H0D B;  2VPB A;  2VPG A;  4GNG A;  2L75 A;  5LKX A;  1WEM A;  4I7D A;  4A49 A;  2K1J A;  2K16 A;  1IYM A;  1WEN A;  4W4U A;  4R2Y A;  1WEW A;  4IC2 A;  2KFT A;  2QIC A;  3O35 A;  3NG2 A;  4GND A;  4AYC B;  5LCW B;  2K4D A;  3N9N A;  5LKZ A;  2MIQ A;  1BOR A;  2G45 A;  2LDR A;  3SOW A;  2Y1M A;  2M85 A;  5G04 B;  3L1X A;  4X3G A;  2MNY A;  5H1V A;  2C2V S;  2LV9 A;  3SOX A;  1FBV A;  2YSJ A;  1Z2Q A;  1JM7 B;  2EA6 A;  3HCT A;  2KWK A;  5B78 A;  4FIP A;  4YAB A;  4YAX A;  2HDP A;  5DIN A;  2ECI A;  2LN0 A;  1V87 A;  2M6M A;  4QF2 A;  4N4F A;  5TBN A;  4ZDT A;  3U5M A;  5TAB A;  3KV5 A;  2Y43 A;  2G6Q A;  2KGG A;  3ZPV E;  2MD8 C;  3ZVZ B;  1LDK C;  1WIM A;  5D1M B;  2KWN A;  2MD7 B;  5FB0 A;  2VNF A;  2VPD A;  2KU3 A;  1JOC A;  3GV4 A;  5B75 A;  3MHH A;  1WGM A;  5TDW A;  5I3L A;  4IC3 A;  5AIU A;  3LRQ A;  3ASL A;  2VJE A;  2VJE B;  4QF3 A;  5H9M A;  2FUU A;  2CKL A;  1LDJ B;  3MHS A;  2LGK A;  2EOD A;  3V43 A;  3EB5 A;  3C6W A;  1T1H A;  1WEE A;  2JMJ A;  4R7E A;  4A0C D;  4UP0 A;  2FSA A;  1RMD A;  3N9M A;  4MVT A;  1Z60 A;  3HCU A;  2VP7 A;  4ZUX U;  3U5O A;  2XEU A;  2ECJ A;  2MUM A;  2Y1N A;  2KWO A;  3M62 A;  3ZNI A;  4I7C A;  1MM3 A;  3O70 A;  2KR4 A;  4UI9 B;  4YAD A;  1WEV A;  4PPE A;  2L5U A;  4YBT A;  4ZQL A;  4P5O B;  1MM2 A;  2PUY A;  3SHB A;  3IHP A;  4YBS A;  1FP0 A;  4C9Z A;  3T6R A;  1WES A;  2BAY A;  5FEY A;  2K17 A;  5C11 A;  3PUQ A;  2JRJ A;  2PNX A;  1K2F A;  2L43 A;  2YHO A;  2ECG A;  2KGI A;  3M63 A;  1WE9 A;  3LQJ A;  2HYE D;  2E6S A;  4Q6F A;  2YU4 A;  4YC9 A;  3RPG B;  1X4U A;  2YSM A;  3ZVY A;  1F62 A;  3DPL R;  3O34 A;  4MSX A;  4A4C A;  3O7A A;  5J3X A;  1G25 A;  3T7L A;  5KH7 A;  2F42 A;  4LLB A;  1DVP A;  1N87 A;  5JG6 A;  3KV6 A;  4NN2 A;  2XB1 A;  2FUI A;  5C13 A;  4S3O B;  4A4B A;  3N9Q A;  2KWJ A;  4WZ2 A;  1VD4 A;  1WEP A;  3U5N A;  4V3K C;  4LKA A;  2DX8 A;  3RPG C;  4GNF A;  2LGL A;  3N9L A;  2OXQ C;  2VPE A;  3C5K A;  1HYI A;  3LQI A;  2CKL B;  2QJ0 A;  5G05 B;  2MNZ A;  1X4I A;  2QIZ A;  5AIT A;  2KE1 A;  3O37 A;  4O64 A;  4WA6 A;  3KQI A;  5EYA F;  4WZ0 A;  5B8D A;  1WFK A;  2NAA A;  3I2D A;  5DKA A;  3FL2 A;  4GNE A;  4N3W A;  2KYU A;  4TKP B;  2MT5 A;  2YQL A;  4BHW A;  3PUR A;  4L58 A;  2YW8 A;  5KH3 A;  2KRE A;  3SOU A;  3U5P A;  4S3O C;  3EB6 A;  4YBM A;  3L1Z B;  5LKU A;  2CSZ A;  4CCG X;  2YHN A;  4BBQ A;  2VJF A;  3DQV R;  3QZV A;  2H0D A;  1U6G B;  1CHC A;  2ECV A;  1HYJ A;  2YUR A;  2ECW A;  3KNV A;  5G0F A;  4R8P K;  2D8S A;  2F6N A;  4YAT A;  5H1U A;  4B7Y C;  1VFY A;  1ZBD B;  4L7X A;  4FO9 A;  5H1T A;  4WZ3 B;  4AVX A;  4LK9 A;  3O36 A;  4AYC A;  5D1K B;  5FER A;  3ZPV 1;  4PTB A;  5B79 A;  5LKT A;  4FK5 A;  3N9P A;  2LQ6 A;  2M1R A;  4F52 B;  2MA5 A;  2YQM A;  4CA1 A;  2L0B A;  4B86 C;  2LXP C;  2MA6 A;  2G43 A;  2YYR A;  4LJN A;  2ECT A;  2F6J A;  1XWH A;  1E4U A;  1WEO A;  2I50 A;  3ZTG A;  2LGV A;  1JM7 A;  1X4J A;  2LRI C;  2CSY A;  4V3L C;  1Z6U A;  2CT2 A;  3HCS A;  5D1L B;  4AP4 A;  4AUQ B;  2EGP A;  2IDA A;  1WEQ A;  4FJC A;  4GB0 A;  3ZYQ A;  1VYX A;  3LQH A;  2JMI A;  5KH9 A;  2E6R A;  2YT5 A;  3GL6 A;  1WIL A;  2AN6 A;  2L80 A;  1WEU A;  2ECN A;  2KIZ A;  5B76 A;  3M99 A;  3L11 A;  3VK6 A;  3N9O A;  2UZG A;  4XI1 A;  4I7B A;  2LXH C;  5TRB A;  2M3H A;  2RI7 A;  2C2L A;  3HTK C;  3PHD A;  2YRE A;  3RTR B;  2RSD A;  4UP5 A;  3O33 A;  5FB1 A;  2LGG A; 
#chains in the Genus database with same CATH topology
 2KKY A;  2XP0 A;  2YUC A;  4LAD B;  2VJF B;  2ZET C;  2XOC A;  5TDR A;  2JMD A;  5B77 A;  2H0D B;  2VPB A;  2VPG A;  4GNG A;  5SVI B;  2L75 A;  5LKX A;  1WEM A;  4I7D A;  4A49 A;  2K1J A;  2K16 A;  1IYM A;  1WEN A;  4W4U A;  4R2Y A;  2P57 A;  1WEW A;  4IC2 A;  2KFT A;  2QIC A;  3O35 A;  3NG2 A;  4GND A;  4AYC B;  2K4D A;  3N9N A;  5LCW B;  3PLW A;  5LKZ A;  2MIQ A;  1BOR A;  2G45 A;  2LDR A;  3SOW A;  2Y1M A;  2M85 A;  5G04 B;  3FAO A;  3L1X A;  4X3G A;  2MNY A;  4F1P A;  5H1V A;  2C2V S;  1DCQ A;  3MDB C;  2LV9 A;  3SOX A;  1FBV A;  2YSJ A;  1Z2Q A;  1JM7 B;  2EA6 A;  3HCT A;  2KWK A;  5B78 A;  4FIP A;  4YAB A;  4YAX A;  2HDP A;  5DIN A;  2ECI A;  2LN0 A;  1V87 A;  2M6M A;  4QF2 A;  4N4F A;  3Q1D A;  5TBN A;  2JM3 A;  2MKE A;  2XOZ A;  4ZDT A;  5SVX A;  3U5M A;  5TAB A;  4QQ4 A;  2DSM A;  3KV5 A;  2Y43 A;  2G6Q A;  2KGG A;  3ZPV E;  2MD8 C;  3ZVZ B;  1LDK C;  1WIM A;  5D1M B;  2KWN A;  2MD7 B;  3T9K A;  5FB0 A;  2VNF A;  2VPD A;  2KU3 A;  1JOC A;  3GV4 A;  5B75 A;  3MHH A;  1WGM A;  5TDW A;  5I3L A;  4IC3 A;  5AIU A;  3LRQ A;  3ASL A;  2VJE A;  2VJE B;  2E61 A;  4QF3 A;  5H9M A;  2FUU A;  2CKL A;  1LDJ B;  3MHS A;  2LGK A;  2DJA A;  2EOD A;  3V43 A;  3EB5 A;  3C6W A;  1T1H A;  1WEE A;  2JMJ A;  4R7E A;  4A0C D;  4UP0 A;  2FSA A;  1RMD A;  3N9M A;  4MVT A;  1Z60 A;  3HCU A;  2VP7 A;  4ZUX U;  3U5O A;  2XEU A;  2ECJ A;  2MUM A;  2Y1N A;  2M13 A;  2KWO A;  3M62 A;  3ZNI A;  4I7C A;  1MM3 A;  3E2D A;  3O70 A;  2KR4 A;  3SUB A;  2CON A;  4UI9 B;  3H7H A;  2CSV A;  4YAD A;  1WEV A;  4PPE A;  2L5U A;  4YBT A;  4ZQL A;  4P5O B;  1MM2 A;  2PUY A;  3SHB A;  3IHP A;  4YBS A;  3KDE C;  1FP0 A;  4C9Z A;  3T6R A;  1WES A;  2BAY A;  5FEY A;  2K17 A;  5C11 A;  3PUQ A;  2JRJ A;  2PNX A;  1K2F A;  2L43 A;  2YHO A;  2ECG A;  2KGI A;  3M63 A;  3LDY A;  1WE9 A;  3LQJ A;  2HYE D;  2LAU A;  2E6S A;  4Q6F A;  2YU4 A;  4YC9 A;  3RPG B;  1X4U A;  2YSM A;  2FFW A;  3ZVY A;  3LJU X;  1F62 A;  3DPL R;  3O34 A;  3O47 A;  4Z0O A;  4MSX A;  4A4C A;  3O7A A;  5J3X A;  1G25 A;  3T7L A;  5KH7 A;  2F42 A;  4LLB A;  1DVP A;  1N87 A;  5JG6 A;  1MBM A;  3FAN A;  3KV6 A;  4NN2 A;  2XB1 A;  2FUI A;  2IQJ A;  5C13 A;  4S3O B;  4A4B A;  3N9Q A;  2KWJ A;  4WZ2 A;  1VD4 A;  2CRW A;  1WEP A;  3U5N A;  4Z0R A;  4V3K C;  4LKA A;  2DX8 A;  3DWD A;  4GNF A;  2LGL A;  3RPG C;  3N9L A;  2OXQ C;  2VPE A;  3C5K A;  1HYI A;  3LQI A;  2CKL B;  2QJ0 A;  5G05 B;  2MNZ A;  1X4I A;  2QIZ A;  5AIT A;  2EXU A;  2KE1 A;  3O37 A;  4O64 A;  4WA6 A;  3KQI A;  5EYA F;  4WZ0 A;  5B8D A;  1WFK A;  2NAA A;  3I2D A;  5DKA A;  3FL2 A;  4GNE A;  4N3W A;  2KYU A;  3FJU B;  4TKP B;  2MT5 A;  4OGE A;  2YQL A;  4BHW A;  3PUR A;  4L58 A;  2YW8 A;  5KH3 A;  2KRE A;  3SOU A;  3U5P A;  4S3O C;  3EB6 A;  4YBM A;  3L1Z B;  5LKU A;  4OGC A;  2CSZ A;  4CCG X;  2YHN A;  4BBQ A;  2VJF A;  3DQV R;  3QZV A;  2H0D A;  1U6G B;  5SVI A;  1CHC A;  2ECV A;  1HYJ A;  2YUR A;  2ECW A;  2XOY A;  3KNV A;  2D8U A;  5G0F A;  2FD4 A;  4R8P K;  2D8S A;  2F6N A;  4YAT A;  3M7K A;  5H1U A;  3DDT A;  4B7Y C;  1VFY A;  2CRR A;  1ZBD B;  4L7X A;  4FO9 A;  5H1T A;  4O62 A;  4WZ3 B;  4AVX A;  4LK9 A;  3O36 A;  4AYC A;  5D1K B;  5FER A;  3ZPV 1;  2JUN A;  4PTB A;  5B79 A;  5LKT A;  4FK5 A;  3N9P A;  5K3Q A;  2LQ6 A;  2M1R A;  4F52 B;  2MA5 A;  2YQM A;  4CA1 A;  2L0B A;  3FM8 C;  2L7P A;  4B86 C;  2LXP C;  2MA6 A;  2G43 A;  2YYR A;  4LJN A;  2ECT A;  2F6J A;  1XWH A;  1E4U A;  1WEO A;  2I50 A;  3ZTG A;  5SVY A;  2RR4 A;  2LGV A;  1JM7 A;  1X4J A;  2LRI C;  2CSY A;  3LVR E;  4V3L C;  1Z6U A;  4H9D A;  2CT2 A;  3HCS A;  3FEH A;  5D1L B;  4AP4 A;  2EGM A;  2OWA A;  4AUQ B;  2EGP A;  2IDA A;  1WEQ A;  4FJC A;  4GB0 A;  3ZYQ A;  1VYX A;  3LQH A;  2JMI A;  5KH9 A;  2E6R A;  2YT5 A;  3JUE A;  3GL6 A;  1WIL A;  2AN6 A;  2L80 A;  1WEU A;  2B0O E;  2ECN A;  2KIZ A;  2YVR A;  5B76 A;  3M99 A;  3L11 A;  3VK6 A;  3N9O A;  2UZG A;  4XI1 A;  4I7B A;  2LXH C;  5TRB A;  2M3H A;  2RI7 A;  2C2L A;  3HTK C;  3PHD A;  2YRE A;  3RTR B;  2RSD A;  2KKX A;  4UP5 A;  3O33 A;  5FB1 A;  3LVQ E;  2LGG A; 
#chains in the Genus database with same CATH homology
 2YUC A;  4LAD B;  2VJF B;  2ZET C;  5TDR A;  2JMD A;  5B77 A;  2H0D B;  2VPB A;  2VPG A;  4GNG A;  2L75 A;  5LKX A;  1WEM A;  4I7D A;  4A49 A;  2K1J A;  2K16 A;  1IYM A;  1WEN A;  4W4U A;  4R2Y A;  1WEW A;  4IC2 A;  2KFT A;  2QIC A;  3O35 A;  3NG2 A;  4GND A;  4AYC B;  5LCW B;  2K4D A;  3N9N A;  5LKZ A;  2MIQ A;  1BOR A;  2G45 A;  2LDR A;  3SOW A;  2Y1M A;  2M85 A;  5G04 B;  3L1X A;  4X3G A;  2MNY A;  5H1V A;  2C2V S;  2LV9 A;  3SOX A;  1FBV A;  2YSJ A;  1Z2Q A;  1JM7 B;  2EA6 A;  3HCT A;  2KWK A;  5B78 A;  4FIP A;  4YAB A;  4YAX A;  2HDP A;  5DIN A;  2ECI A;  2LN0 A;  1V87 A;  2M6M A;  4QF2 A;  4N4F A;  5TBN A;  4ZDT A;  3U5M A;  5TAB A;  3KV5 A;  2Y43 A;  2G6Q A;  2KGG A;  3ZPV E;  2MD8 C;  3ZVZ B;  1LDK C;  1WIM A;  5D1M B;  2KWN A;  2MD7 B;  5FB0 A;  2VNF A;  2VPD A;  2KU3 A;  1JOC A;  3GV4 A;  5B75 A;  3MHH A;  1WGM A;  5TDW A;  5I3L A;  4IC3 A;  5AIU A;  3LRQ A;  3ASL A;  2VJE A;  2VJE B;  4QF3 A;  5H9M A;  2FUU A;  2CKL A;  1LDJ B;  3MHS A;  2LGK A;  2EOD A;  3V43 A;  3EB5 A;  3C6W A;  1T1H A;  1WEE A;  2JMJ A;  4R7E A;  4A0C D;  4UP0 A;  2FSA A;  1RMD A;  3N9M A;  4MVT A;  1Z60 A;  3HCU A;  2VP7 A;  4ZUX U;  3U5O A;  2XEU A;  2ECJ A;  2MUM A;  2Y1N A;  2KWO A;  3M62 A;  3ZNI A;  4I7C A;  1MM3 A;  3O70 A;  2KR4 A;  4UI9 B;  4YAD A;  1WEV A;  4PPE A;  2L5U A;  4YBT A;  4ZQL A;  4P5O B;  1MM2 A;  2PUY A;  3SHB A;  3IHP A;  4YBS A;  1FP0 A;  4C9Z A;  3T6R A;  1WES A;  2BAY A;  5FEY A;  2K17 A;  5C11 A;  3PUQ A;  2JRJ A;  2PNX A;  1K2F A;  2L43 A;  2YHO A;  2ECG A;  2KGI A;  3M63 A;  1WE9 A;  3LQJ A;  2HYE D;  2E6S A;  4Q6F A;  2YU4 A;  4YC9 A;  3RPG B;  1X4U A;  2YSM A;  3ZVY A;  1F62 A;  3DPL R;  3O34 A;  4MSX A;  4A4C A;  3O7A A;  5J3X A;  1G25 A;  3T7L A;  5KH7 A;  2F42 A;  4LLB A;  1DVP A;  1N87 A;  5JG6 A;  3KV6 A;  4NN2 A;  2XB1 A;  2FUI A;  5C13 A;  4S3O B;  4A4B A;  3N9Q A;  2KWJ A;  4WZ2 A;  1VD4 A;  1WEP A;  3U5N A;  4V3K C;  4LKA A;  2DX8 A;  3RPG C;  4GNF A;  2LGL A;  3N9L A;  2OXQ C;  2VPE A;  3C5K A;  1HYI A;  3LQI A;  2CKL B;  2QJ0 A;  5G05 B;  2MNZ A;  1X4I A;  2QIZ A;  5AIT A;  2KE1 A;  3O37 A;  4O64 A;  4WA6 A;  3KQI A;  5EYA F;  4WZ0 A;  5B8D A;  1WFK A;  2NAA A;  3I2D A;  5DKA A;  3FL2 A;  4GNE A;  4N3W A;  2KYU A;  4TKP B;  2MT5 A;  2YQL A;  4BHW A;  3PUR A;  4L58 A;  2YW8 A;  5KH3 A;  2KRE A;  3SOU A;  3U5P A;  4S3O C;  3EB6 A;  4YBM A;  3L1Z B;  5LKU A;  2CSZ A;  4CCG X;  2YHN A;  4BBQ A;  2VJF A;  3DQV R;  3QZV A;  2H0D A;  1U6G B;  1CHC A;  2ECV A;  1HYJ A;  2YUR A;  2ECW A;  3KNV A;  5G0F A;  4R8P K;  2D8S A;  2F6N A;  4YAT A;  5H1U A;  4B7Y C;  1VFY A;  1ZBD B;  4L7X A;  4FO9 A;  5H1T A;  4WZ3 B;  4AVX A;  4LK9 A;  3O36 A;  4AYC A;  5D1K B;  5FER A;  3ZPV 1;  4PTB A;  5B79 A;  5LKT A;  4FK5 A;  3N9P A;  2LQ6 A;  2M1R A;  4F52 B;  2MA5 A;  2YQM A;  4CA1 A;  2L0B A;  4B86 C;  2LXP C;  2MA6 A;  2G43 A;  2YYR A;  4LJN A;  2ECT A;  2F6J A;  1XWH A;  1E4U A;  1WEO A;  2I50 A;  3ZTG A;  2LGV A;  1JM7 A;  1X4J A;  2LRI C;  2CSY A;  4V3L C;  1Z6U A;  2CT2 A;  3HCS A;  5D1L B;  4AP4 A;  4AUQ B;  2EGP A;  2IDA A;  1WEQ A;  4FJC A;  4GB0 A;  3ZYQ A;  1VYX A;  3LQH A;  2JMI A;  5KH9 A;  2E6R A;  2YT5 A;  3GL6 A;  1WIL A;  2AN6 A;  2L80 A;  1WEU A;  2ECN A;  2KIZ A;  5B76 A;  3M99 A;  3L11 A;  3VK6 A;  3N9O A;  2UZG A;  4XI1 A;  4I7B A;  2LXH C;  5TRB A;  2M3H A;  2RI7 A;  2C2L A;  3HTK C;  3PHD A;  2YRE A;  3RTR B;  2RSD A;  4UP5 A;  3O33 A;  5FB1 A;  2LGG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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