2XOYA

C-terminal cysteine-rich domain of human chfr bound to p(1),p(2)- diadenosine-5'-pyrophosphate
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
239
structure length
212
Chain Sequence
PYVVCRQCPEYRRQAAQPPHCPDYVCPLQGSHALCTCCFQPMPDRRVEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYESDILKNYLATRGLTWKNMLTESLVALQRGVFLLSDYRVTGDTVLCYCCGLRSFRELTYQYRQNIPASELPVAVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of Poly(Adp-Ribose) Recognition by the Multizinc Binding Domain of Checkpoint with Forkhead-Associated and Ring Domains (Chfr).
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE CHFR
total genus 65
structure length 212
sequence length 239
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2010-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF10283 zf-CCHH PBZ domain
A PF17979 zf-CRD Cysteine rich domain with multizinc binding regions
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.140 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Herpes Virus-1 2xoyA01
2XOZA 2XOCA 2XP0A 2XOYA
chains in the Genus database with same CATH superfamily
2JMIA 2XB1A 3DQVR 2OXQC 1RMDA 2XOCA 2MD8C 4UP5A 1WEVA 5B78A 2EODA 2H0DB 3I2DA 5TABA 2LGVA 3EB5A 4YATA 2FUUA 2HDPA 3HTKC 2KFTA 3FM8C 3PLWA 2EGPA 3N9MA 5FB1A 3EB6A 2KWOA 1U6GB 1VD4A 4LADB 2M1RA 2MUMA 2VJEB 1CHCA 2ECTA 2MNYA 5TDWA 1Z2QA 3KQIA 4GNGA 4O64A 4R7EA 1VFYA 4Z0OA 1MBMA 4ZQLA 3L1XA 5H1UA 2VPBA 2EXUA 3IHPA 2ECWA 3JUEA 4LJNA 3LVRE 3M7KA 2VJFB 2RI7A 5D1LB 5KH7A 4FIPA 4AYCA 4TKPB 3V43A 2KGGA 3M99A 1BORA 2LQ6A 5TRBA 4H9DA 2G6QA 3U5NA 2B0OE 3LVQE 3PURA 2KWKA 2XP0A 2MIQA 3M62A 2HYED 4L58A 2KGIA 3LDYA 3E2DA 2KKXA 2QICA 4OGEA 3C5KA 3ZVYA 2YSJA 4CA1A 2YT5A 4YAXA 1X4IA 3MDBC 3N9LA 5B75A 5I3LA 2FD4A 3O35A 1G25A 2ECGA 3HCUA 3T7LA 5B8DA 5J3XA 2ECVA 3KV5A 2H0DA 2JMJA 4A0CD 3GV4A 2KE1A 4N3WA 5LKZA 4B86C 2LXPC 2Y43A 5B77A 3RTRB 5TBNA 2VPEA 3O33A 1Z60A 5G05B 1F62A 2RSDA 4A4BA 2CSVA 4W4UA 2L80A 2VJEA 2KREA 3U5OA 2ZETC 1E4UA 5FEYA 4AVXA 5H1VA 2L5UA 2JM3A 1JM7B 2XEUA 2YHOA 2P57A 2JMDA 2YSMA 3SOUA 2KKYA 4YBSA 2LGKA 4YC9A 2JRJA 2YW8A 2KYUA 4L7XA 2VJFA 2CSZA 4S3OC 3HCTA 1JOCA 3ZVZB 3FAOA 2MA6A 2KU3A 3PUQA 4O62A 3O36A 3T6RA 2F6NA 3T9KA 2VNFA 1FP0A 3ZPVE 5JG6A 1WGMA 3KNVA 2BAYA 1K2FA 4ZUXU 3PHDA 2ECIA 1LDJB 2Y1MA 2YVRA 4NN2A 3N9PA 4LLBA 4CCGX 5LCWB 1LDKC 2LRIC 4QF2A 4P5OB 3O70A 2LGGA 5DINA 3SOXA 2YQMA 5KH3A 2KWJA 2E61A 2K4DA 3N9OA 3GL6A 1MM3A 4MSXA 2YREA 1WESA 5FERA 2UZGA 1HYIA 2PUYA 2L7PA 3LRQA 4WZ0A 2ECNA 3DPLR 3RPGB 1WEUA 2CONA 2F42A 4GNEA 1VYXA 3QZVA 5G04B 2C2LA 1T1HA 4IC2A 5D1KB 1WE9A 3ZTGA 3RPGC 2VPGA 4I7BA 2OWAA 5B79A 4PPEA 1JM7A 2RR4A 2ECJA 1FBVA 2VPDA 5K3QA 4F52B 2LXHC 2JUNA 2IDAA 4I7DA 5LKUA 2L0BA 4BBQA 3L11A 2KIZA 4AUQB 3N9NA 3LJUX 1WEQA 2DX8A 2EGMA 3ZPV1 3U5MA 4YADA 2XOZA 2CSYA 4GB0A 4V3KC 3DDTA 3SOWA 2K16A 3C6WA 4F1PA 2YYRA 2LN0A 4WZ2A 2C2VS 5SVYA 4FJCA 4UP0A 4R8PK 2KR4A 3LQIA 1WILA 2IQJA 4N4FA 3LQHA 4A4CA 4PTBA 4GNDA 2VP7A 2G45A 2I50A 1ZBDB 2KWNA 4S3OB 5H9MA 4IC3A 4UI9B 4R2YA 2YQLA 3SUBA 4GNFA 1XWHA 4FO9A 3FL2A 1WFKA 2LGLA 2M3HA 5AITA 2Y1NA 3MHSA 4WA6A 2DSMA 2E6SA 2MNZA 5SVIB 1HYJA 1WIMA 1WEMA 3FJUB 3HCSA 5SVXA 2FFWA 1WEOA 3O37A 4YBTA 4ZDTA 4YABA 5C13A 2AN6A 5EYAF 3SHBA 5C11A 5D1MB 3FEHA 2L75A 5H1TA 2G43A 2MA5A 1X4UA 2MKEA 4MVTA 4AP4A 3H7HA 4Z0RA 3L1ZB 2XOYA 2CRWA 5FB0A 1MM2A 1WEEA 3ZNIA 2LDRA 2LAUA 2CKLB 4C9ZA 2M13A 3U5PA 4FK5A 1DCQA 4BHWA 1WEWA 4V3LC 5LKTA 4X3GA 4OGCA 2PNXA 2YU4A 1X4JA 2K17A 3DWDA 3N9QA 2L43A 5B76A 4Q6FA 2M85A 1WENA 3ZYQA 3MHHA 2FSAA 5KH9A 1Z6UA 2K1JA 5TDRA 3ASLA 4A49A 1IYMA 5LKXA 2LV9A 2MT5A 2QIZA 1DVPA 2E6RA 3FANA 4LKAA 2DJAA 2YURA 5SVIA 4I7CA 2CRRA 2CT2A 2D8UA 4QQ4A 3VK6A 4YBMA 5G0FA 2D8SA 2FUIA 4LK9A 4B7YC 4AYCB 2MD7B 1V87A 2NAAA 4QF3A 4XI1A 3O47A 5AIUA 3Q1DA 2YHNA 3KV6A 3O34A 4WZ3B 3O7AA 3NG2A 5DKAA 2M6MA 1N87A 2F6JA 3KDEC 2EA6A 3LQJA 2CKLA 1WEPA 2QJ0A 3M63A 2YUCA
chains in the Genus database with same CATH topology
2JM3A 3FM8C 2EGMA 3PLWA 5SVIB 3H7HA 4Z0RA 2XOZA 3JUEA 3T9KA 2XOYA 2P57A 3LVRE 3M7KA 2KKYA 3DDTA 3FJUB 2OWAA 2XOCA 2CRWA 2DJAA 3O47A 3Q1DA 5SVXA 3LDYA 2E61A 3E2DA 2KKXA 2FFWA 2RR4A 5SVIA 3SUBA 4OGEA 4F1PA 5K3QA 2LAUA 2YREA 2CSVA 2M13A 5SVYA 2JUNA 2YVRA 3MDBC 4H9DA 1DCQA 2CRRA 2FD4A 4Z0OA 2L7PA 3KDEC 3LJUX 3FEHA 2D8UA 4OGCA 4QQ4A 2B0OE 3LVQE 2CONA 2XP0A 2IQJA 2EXUA 2MKEA 4O62A 3DWDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XOZ A;  2XOC A;  2XP0 A;  2XOY A; 
#chains in the Genus database with same CATH topology
 2JMI A;  2XB1 A;  3DQV R;  2OXQ C;  1RMD A;  2XOC A;  2MD8 C;  4UP5 A;  1WEV A;  5B78 A;  2EOD A;  2H0D B;  3I2D A;  5TAB A;  2LGV A;  3EB5 A;  4YAT A;  2FUU A;  2HDP A;  3HTK C;  2KFT A;  3FM8 C;  3PLW A;  2EGP A;  3N9M A;  5FB1 A;  3EB6 A;  2KWO A;  1U6G B;  1VD4 A;  4LAD B;  2M1R A;  2MUM A;  2VJE B;  1CHC A;  2ECT A;  2MNY A;  5TDW A;  1Z2Q A;  3KQI A;  4GNG A;  4O64 A;  4R7E A;  1VFY A;  4Z0O A;  1MBM A;  4ZQL A;  3L1X A;  5H1U A;  2VPB A;  2EXU A;  3IHP A;  2ECW A;  3JUE A;  4LJN A;  3LVR E;  3M7K A;  2VJF B;  2RI7 A;  5D1L B;  5KH7 A;  4FIP A;  4AYC A;  4TKP B;  3V43 A;  2KGG A;  3M99 A;  1BOR A;  2LQ6 A;  5TRB A;  4H9D A;  2G6Q A;  3U5N A;  2B0O E;  3LVQ E;  3PUR A;  2KWK A;  2XP0 A;  2MIQ A;  3M62 A;  2HYE D;  4L58 A;  2KGI A;  3LDY A;  3E2D A;  2KKX A;  2QIC A;  4OGE A;  3C5K A;  3ZVY A;  2YSJ A;  4CA1 A;  2YT5 A;  4YAX A;  1X4I A;  3MDB C;  3N9L A;  5B75 A;  5I3L A;  2FD4 A;  3O35 A;  1G25 A;  2ECG A;  3HCU A;  3T7L A;  5B8D A;  5J3X A;  2ECV A;  3KV5 A;  2H0D A;  2JMJ A;  4A0C D;  3GV4 A;  2KE1 A;  4N3W A;  5LKZ A;  4B86 C;  2LXP C;  2Y43 A;  5B77 A;  3RTR B;  5TBN A;  2VPE A;  3O33 A;  1Z60 A;  5G05 B;  1F62 A;  2RSD A;  4A4B A;  2CSV A;  4W4U A;  2L80 A;  2VJE A;  2KRE A;  3U5O A;  2ZET C;  1E4U A;  5FEY A;  4AVX A;  5H1V A;  2L5U A;  2JM3 A;  1JM7 B;  2XEU A;  2YHO A;  2P57 A;  2JMD A;  2YSM A;  3SOU A;  2KKY A;  4YBS A;  2LGK A;  4YC9 A;  2JRJ A;  2YW8 A;  2KYU A;  4L7X A;  2VJF A;  2CSZ A;  4S3O C;  3HCT A;  1JOC A;  3ZVZ B;  3FAO A;  2MA6 A;  2KU3 A;  3PUQ A;  4O62 A;  3O36 A;  3T6R A;  2F6N A;  3T9K A;  2VNF A;  1FP0 A;  3ZPV E;  5JG6 A;  1WGM A;  3KNV A;  2BAY A;  1K2F A;  4ZUX U;  3PHD A;  2ECI A;  1LDJ B;  2Y1M A;  2YVR A;  4NN2 A;  3N9P A;  4LLB A;  4CCG X;  5LCW B;  1LDK C;  2LRI C;  4QF2 A;  4P5O B;  3O70 A;  2LGG A;  5DIN A;  3SOX A;  2YQM A;  5KH3 A;  2KWJ A;  2E61 A;  2K4D A;  3N9O A;  3GL6 A;  1MM3 A;  4MSX A;  2YRE A;  1WES A;  5FER A;  2UZG A;  1HYI A;  2PUY A;  2L7P A;  3LRQ A;  4WZ0 A;  2ECN A;  3DPL R;  3RPG B;  1WEU A;  2CON A;  2F42 A;  4GNE A;  1VYX A;  3QZV A;  5G04 B;  2C2L A;  1T1H A;  4IC2 A;  5D1K B;  1WE9 A;  3ZTG A;  3RPG C;  2VPG A;  4I7B A;  2OWA A;  5B79 A;  4PPE A;  1JM7 A;  2RR4 A;  2ECJ A;  1FBV A;  2VPD A;  5K3Q A;  4F52 B;  2LXH C;  2JUN A;  2IDA A;  4I7D A;  5LKU A;  2L0B A;  4BBQ A;  3L11 A;  2KIZ A;  4AUQ B;  3N9N A;  3LJU X;  1WEQ A;  2DX8 A;  2EGM A;  3ZPV 1;  3U5M A;  4YAD A;  2XOZ A;  2CSY A;  4GB0 A;  4V3K C;  3DDT A;  3SOW A;  2K16 A;  3C6W A;  4F1P A;  2YYR A;  2LN0 A;  4WZ2 A;  2C2V S;  5SVY A;  4FJC A;  4UP0 A;  4R8P K;  2KR4 A;  3LQI A;  1WIL A;  2IQJ A;  4N4F A;  3LQH A;  4A4C A;  4PTB A;  4GND A;  2VP7 A;  2G45 A;  2I50 A;  1ZBD B;  2KWN A;  4S3O B;  5H9M A;  4IC3 A;  4UI9 B;  4R2Y A;  2YQL A;  3SUB A;  4GNF A;  1XWH A;  4FO9 A;  3FL2 A;  1WFK A;  2LGL A;  2M3H A;  5AIT A;  2Y1N A;  3MHS A;  4WA6 A;  2DSM A;  2E6S A;  2MNZ A;  5SVI B;  1HYJ A;  1WIM A;  1WEM A;  3FJU B;  3HCS A;  5SVX A;  2FFW A;  1WEO A;  3O37 A;  4YBT A;  4ZDT A;  4YAB A;  5C13 A;  2AN6 A;  5EYA F;  3SHB A;  5C11 A;  5D1M B;  3FEH A;  2L75 A;  5H1T A;  2G43 A;  2MA5 A;  1X4U A;  2MKE A;  4MVT A;  4AP4 A;  3H7H A;  4Z0R A;  3L1Z B;  2XOY A;  2CRW A;  5FB0 A;  1MM2 A;  1WEE A;  3ZNI A;  2LDR A;  2LAU A;  2CKL B;  4C9Z A;  2M13 A;  3U5P A;  4FK5 A;  1DCQ A;  4BHW A;  1WEW A;  4V3L C;  5LKT A;  4X3G A;  4OGC A;  2PNX A;  2YU4 A;  1X4J A;  2K17 A;  3DWD A;  3N9Q A;  2L43 A;  5B76 A;  4Q6F A;  2M85 A;  1WEN A;  3ZYQ A;  3MHH A;  2FSA A;  5KH9 A;  1Z6U A;  2K1J A;  5TDR A;  3ASL A;  4A49 A;  1IYM A;  5LKX A;  2LV9 A;  2MT5 A;  2QIZ A;  1DVP A;  2E6R A;  3FAN A;  4LKA A;  2DJA A;  2YUR A;  5SVI A;  4I7C A;  2CRR A;  2CT2 A;  2D8U A;  4QQ4 A;  3VK6 A;  4YBM A;  5G0F A;  2D8S A;  2FUI A;  4LK9 A;  4B7Y C;  4AYC B;  2MD7 B;  1V87 A;  2NAA A;  4QF3 A;  4XI1 A;  3O47 A;  5AIU A;  3Q1D A;  2YHN A;  3KV6 A;  3O34 A;  4WZ3 B;  3O7A A;  3NG2 A;  5DKA A;  2M6M A;  1N87 A;  2F6J A;  3KDE C;  2EA6 A;  3LQJ A;  2CKL A;  1WEP A;  2QJ0 A;  3M63 A;  2YUC A; 
#chains in the Genus database with same CATH homology
 2JM3 A;  3FM8 C;  2EGM A;  3PLW A;  5SVI B;  3H7H A;  4Z0R A;  2XOZ A;  3JUE A;  3T9K A;  2XOY A;  2P57 A;  3LVR E;  3M7K A;  2KKY A;  3DDT A;  3FJU B;  2OWA A;  2XOC A;  2CRW A;  2DJA A;  3O47 A;  3Q1D A;  5SVX A;  3LDY A;  2E61 A;  3E2D A;  2KKX A;  2FFW A;  2RR4 A;  5SVI A;  3SUB A;  4OGE A;  4F1P A;  5K3Q A;  2LAU A;  2YRE A;  2CSV A;  2M13 A;  5SVY A;  2JUN A;  2YVR A;  3MDB C;  4H9D A;  1DCQ A;  2CRR A;  2FD4 A;  4Z0O A;  2L7P A;  3KDE C;  3LJU X;  3FEH A;  2D8U A;  4OGC A;  4QQ4 A;  2B0O E;  3LVQ E;  2CON A;  2XP0 A;  2IQJ A;  2EXU A;  2MKE A;  4O62 A;  3DWD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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