3KDEC

Crystal structure of the thap domain from d. melanogaster p-element transposase in complex with its natural dna binding site
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
76
structure length
74
Chain Sequence
MKYCKFCCKAVTGVKLIHVPKCAIKRKLWEQSLGCSLGENSQICDTHFNDSQWKAAKGQTFKRRRLNADAVPSK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves.
pubmed doi rcsb
molecule tags Dna binding protein/dna
source organism Drosophila melanogaster
molecule keywords 5'-D(*GP*TP*TP*AP*AP*GP*(BRU)P*GP*GP*A)-3'
total genus 13
structure length 74
sequence length 76
ec nomenclature
pdb deposition date 2009-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF05485 THAP THAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.180 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Herpes Virus-1 3kdeC01
3KDEC 2LAUA 2JM3A
chains in the Genus database with same CATH superfamily
2CKLB 4FO9A 5LKZA 2MIQA 2RR4A 5FB0A 1FP0A 5LCWB 3N9MA 1WFKA 4WZ3B 2KWOA 4UP0A 2YT5A 2LGKA 2LGLA 3KDEC 2XOCA 3N9OA 2EGMA 4Z0OA 2KWNA 4WZ0A 4YATA 4UP5A 2FUIA 3O47A 2KGGA 5B78A 3RPGB 4O62A 4L58A 2CSVA 3FJUB 1JM7A 4ZQLA 2YSJA 3MDBC 3ZVYA 1XWHA 5LKXA 4YADA 4ZDTA 3T9KA 3FM8C 3GV4A 3SHBA 1WILA 2YQLA 1WE9A 4MVTA 1WEUA 3O36A 3HCUA 3JUEA 4ZUXU 3MHHA 2JRJA 4I7CA 2L7PA 2MKEA 2XP0A 2E6SA 2VPDA 2LDRA 4UI9B 4W4UA 1MBMA 2YUCA 2ECIA 3LDYA 4OGEA 1JM7B 2L5UA 1DVPA 5B76A 4GB0A 2E6RA 4YBSA 2K4DA 1VYXA 2M3HA 2MA6A 5J3XA 2MNYA 3I2DA 3GL6A 4GNEA 3LQIA 1Z60A 4Q6FA 5C13A 3DDTA 2MNZA 5DINA 2ZETC 2ECNA 5SVIA 3LVRE 1WEVA 3O7AA 4BBQA 4QQ4A 2FFWA 4MSXA 2LGGA 2KYUA 2LXPC 3U5PA 3QZVA 5TRBA 4LJNA 3NG2A 2FSAA 3HCTA 2XB1A 1WGMA 3DWDA 2XEUA 2BAYA 2Y1NA 1WEEA 2YHOA 3PUQA 1FBVA 3ASLA 1N87A 4L7XA 4N3WA 4GNGA 2KU3A 5EYAF 3IHPA 1WEQA 5H9MA 1G25A 2E61A 3KV5A 2CT2A 2RI7A 3LRQA 2H0DB 5FEYA 2C2VS 2DX8A 2MT5A 5KH3A 3M99A 3L1ZB 3SOXA 4IC3A 4X3GA 2F42A 2G45A 2KIZA 4F52B 3ZYQA 2LN0A 2F6JA 2JMJA 4GNFA 2L43A 3EB5A 2IQJA 2FD4A 4F1PA 2ECWA 1RMDA 2L80A 3RPGC 4CCGX 1E4UA 4FK5A 1U6GB 3N9QA 3SUBA 4P5OB 3O35A 4LK9A 2F6NA 2AN6A 4GNDA 2KKXA 2KWKA 2RSDA 4YABA 2L75A 5DKAA 5TBNA 3VK6A 3HCSA 4QF2A 4A0CD 1BORA 2B0OE 4IC2A 4V3LC 2KFTA 2KE1A 2JM3A 2CONA 4H9DA 3U5MA 2YHNA 2JMIA 2PUYA 2P57A 2YQMA 3LJUX 4FJCA 2QICA 4I7DA 3FL2A 1MM3A 1X4UA 3C6WA 1WEPA 4YC9A 3LVQE 3ZVZB 2VJEA 4S3OB 4A4BA 2K1JA 4O64A 2MD7B 2UZGA 2KKYA 3FANA 4R8PK 1WEMA 2YREA 3M62A 3KQIA 2ECJA 5JG6A 4AP4A 2CSZA 1LDKC 2JUNA 1IYMA 2YU4A 4AUQB 4YBMA 2M13A 4R2YA 4PPEA 2VJEB 2L0BA 5H1TA 3SOUA 1WIMA 3ZNIA 5G04B 5B8DA 5KH9A 4NN2A 3L11A 5SVIB 1VFYA 2LV9A 2LXHC 3PHDA 4V3KC 4YBTA 1WESA 1CHCA 2CRWA 3DQVR 5D1KB 3Q1DA 3T6RA 5SVXA 3EB6A 1F62A 2KWJA 2KREA 2JMDA 2VPBA 2HDPA 2IDAA 2VNFA 5D1MB 3M63A 2KGIA 3PLWA 1Z2QA 2ECGA 2FUUA 2ECVA 2K16A 1LDJB 3FAOA 4FIPA 2Y1MA 2XOYA 5KH7A 1Z6UA 3C5KA 2G43A 2LRIC 3RTRB 4OGCA 2C2LA 5TABA 5SVYA 2Y43A 2G6QA 2VPGA 3U5OA 2PNXA 3O34A 3M7KA 4AYCA 1K2FA 2VPEA 5AITA 2EA6A 4QF3A 3MHSA 5I3LA 4LADB 4B86C 5TDRA 2QJ0A 2YSMA 3KV6A 3U5NA 3PURA 2D8SA 2LGVA 2M6MA 2YURA 2QIZA 5LKUA 4R7EA 1WENA 3V43A 4I7BA 5LKTA 1ZBDB 2LAUA 2YYRA 5TDWA 5B75A 2YW8A 2M85A 4AYCB 2ECTA 2DJAA 2EGPA 3LQHA 3SOWA 1T1HA 2OWAA 3N9LA 4B7YC 3KNVA 5B77A 3O70A 1X4JA 2MUMA 1WEWA 3O33A 3DPLR 1MM2A 1JOCA 4PTBA 4WZ2A 5H1UA 4S3OC 4LKAA 3HTKC 2EODA 4YAXA 4AVXA 1DCQA 4LLBA 2NAAA 3H7HA 5K3QA 5C11A 2EXUA 5D1LB 4A49A 2DSMA 4TKPB 4WA6A 3T7LA 4BHWA 3E2DA 4XI1A 4C9ZA 3ZPVE 4CA1A 2VJFA 5B79A 2CRRA 1VD4A 1X4IA 2XOZA 3O37A 3ZTGA 4N4FA 5G0FA 3N9PA 2VP7A 1V87A 1HYJA 2CKLA 2OXQC 1WEOA 3ZPV1 4Z0RA 5FB1A 2MD8C 5AIUA 2H0DA 3L1XA 2MA5A 2M1RA 3LQJA 2D8UA 2KR4A 1HYIA 2I50A 5G05B 5H1VA 5FERA 2CSYA 2LQ6A 3N9NA 3FEHA 4A4CA 2VJFB 2HYED 2YVRA 2K17A
chains in the Genus database with same CATH topology
2KKXA 2P57A 3H7HA 2L7PA 2MKEA 3LJUX 2XOYA 5K3QA 2E61A 3O47A 2XP0A 2EXUA 2OWAA 2CRWA 2JUNA 3E2DA 3LVQE 2D8UA 2RR4A 4O62A 4OGCA 3DDTA 2CSVA 3FJUB 5SVYA 3Q1DA 3DWDA 3LDYA 3M7KA 2M13A 5SVXA 4OGEA 2LAUA 3MDBC 2CRRA 2IQJA 2FD4A 4F1PA 4Z0RA 2B0OE 2XOZA 5SVIA 3LVRE 3T9KA 3FM8C 2KKYA 3FEHA 2YVRA 3PLWA 4Z0OA 3SUBA 4QQ4A 2FFWA 2YREA 2JM3A 3KDEC 3JUEA 2CONA 2XOCA 5SVIB 4H9DA 2EGMA 1DCQA 2DJAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KDE C;  2LAU A;  2JM3 A; 
#chains in the Genus database with same CATH topology
 2CKL B;  4FO9 A;  5LKZ A;  2MIQ A;  2RR4 A;  5FB0 A;  1FP0 A;  5LCW B;  3N9M A;  1WFK A;  4WZ3 B;  2KWO A;  4UP0 A;  2YT5 A;  2LGK A;  2LGL A;  3KDE C;  2XOC A;  3N9O A;  2EGM A;  4Z0O A;  2KWN A;  4WZ0 A;  4YAT A;  4UP5 A;  2FUI A;  3O47 A;  2KGG A;  5B78 A;  3RPG B;  4O62 A;  4L58 A;  2CSV A;  3FJU B;  1JM7 A;  4ZQL A;  2YSJ A;  3MDB C;  3ZVY A;  1XWH A;  5LKX A;  4YAD A;  4ZDT A;  3T9K A;  3FM8 C;  3GV4 A;  3SHB A;  1WIL A;  2YQL A;  1WE9 A;  4MVT A;  1WEU A;  3O36 A;  3HCU A;  3JUE A;  4ZUX U;  3MHH A;  2JRJ A;  4I7C A;  2L7P A;  2MKE A;  2XP0 A;  2E6S A;  2VPD A;  2LDR A;  4UI9 B;  4W4U A;  1MBM A;  2YUC A;  2ECI A;  3LDY A;  4OGE A;  1JM7 B;  2L5U A;  1DVP A;  5B76 A;  4GB0 A;  2E6R A;  4YBS A;  2K4D A;  1VYX A;  2M3H A;  2MA6 A;  5J3X A;  2MNY A;  3I2D A;  3GL6 A;  4GNE A;  3LQI A;  1Z60 A;  4Q6F A;  5C13 A;  3DDT A;  2MNZ A;  5DIN A;  2ZET C;  2ECN A;  5SVI A;  3LVR E;  1WEV A;  3O7A A;  4BBQ A;  4QQ4 A;  2FFW A;  4MSX A;  2LGG A;  2KYU A;  2LXP C;  3U5P A;  3QZV A;  5TRB A;  4LJN A;  3NG2 A;  2FSA A;  3HCT A;  2XB1 A;  1WGM A;  3DWD A;  2XEU A;  2BAY A;  2Y1N A;  1WEE A;  2YHO A;  3PUQ A;  1FBV A;  3ASL A;  1N87 A;  4L7X A;  4N3W A;  4GNG A;  2KU3 A;  5EYA F;  3IHP A;  1WEQ A;  5H9M A;  1G25 A;  2E61 A;  3KV5 A;  2CT2 A;  2RI7 A;  3LRQ A;  2H0D B;  5FEY A;  2C2V S;  2DX8 A;  2MT5 A;  5KH3 A;  3M99 A;  3L1Z B;  3SOX A;  4IC3 A;  4X3G A;  2F42 A;  2G45 A;  2KIZ A;  4F52 B;  3ZYQ A;  2LN0 A;  2F6J A;  2JMJ A;  4GNF A;  2L43 A;  3EB5 A;  2IQJ A;  2FD4 A;  4F1P A;  2ECW A;  1RMD A;  2L80 A;  3RPG C;  4CCG X;  1E4U A;  4FK5 A;  1U6G B;  3N9Q A;  3SUB A;  4P5O B;  3O35 A;  4LK9 A;  2F6N A;  2AN6 A;  4GND A;  2KKX A;  2KWK A;  2RSD A;  4YAB A;  2L75 A;  5DKA A;  5TBN A;  3VK6 A;  3HCS A;  4QF2 A;  4A0C D;  1BOR A;  2B0O E;  4IC2 A;  4V3L C;  2KFT A;  2KE1 A;  2JM3 A;  2CON A;  4H9D A;  3U5M A;  2YHN A;  2JMI A;  2PUY A;  2P57 A;  2YQM A;  3LJU X;  4FJC A;  2QIC A;  4I7D A;  3FL2 A;  1MM3 A;  1X4U A;  3C6W A;  1WEP A;  4YC9 A;  3LVQ E;  3ZVZ B;  2VJE A;  4S3O B;  4A4B A;  2K1J A;  4O64 A;  2MD7 B;  2UZG A;  2KKY A;  3FAN A;  4R8P K;  1WEM A;  2YRE A;  3M62 A;  3KQI A;  2ECJ A;  5JG6 A;  4AP4 A;  2CSZ A;  1LDK C;  2JUN A;  1IYM A;  2YU4 A;  4AUQ B;  4YBM A;  2M13 A;  4R2Y A;  4PPE A;  2VJE B;  2L0B A;  5H1T A;  3SOU A;  1WIM A;  3ZNI A;  5G04 B;  5B8D A;  5KH9 A;  4NN2 A;  3L11 A;  5SVI B;  1VFY A;  2LV9 A;  2LXH C;  3PHD A;  4V3K C;  4YBT A;  1WES A;  1CHC A;  2CRW A;  3DQV R;  5D1K B;  3Q1D A;  3T6R A;  5SVX A;  3EB6 A;  1F62 A;  2KWJ A;  2KRE A;  2JMD A;  2VPB A;  2HDP A;  2IDA A;  2VNF A;  5D1M B;  3M63 A;  2KGI A;  3PLW A;  1Z2Q A;  2ECG A;  2FUU A;  2ECV A;  2K16 A;  1LDJ B;  3FAO A;  4FIP A;  2Y1M A;  2XOY A;  5KH7 A;  1Z6U A;  3C5K A;  2G43 A;  2LRI C;  3RTR B;  4OGC A;  2C2L A;  5TAB A;  5SVY A;  2Y43 A;  2G6Q A;  2VPG A;  3U5O A;  2PNX A;  3O34 A;  3M7K A;  4AYC A;  1K2F A;  2VPE A;  5AIT A;  2EA6 A;  4QF3 A;  3MHS A;  5I3L A;  4LAD B;  4B86 C;  5TDR A;  2QJ0 A;  2YSM A;  3KV6 A;  3U5N A;  3PUR A;  2D8S A;  2LGV A;  2M6M A;  2YUR A;  2QIZ A;  5LKU A;  4R7E A;  1WEN A;  3V43 A;  4I7B A;  5LKT A;  1ZBD B;  2LAU A;  2YYR A;  5TDW A;  5B75 A;  2YW8 A;  2M85 A;  4AYC B;  2ECT A;  2DJA A;  2EGP A;  3LQH A;  3SOW A;  1T1H A;  2OWA A;  3N9L A;  4B7Y C;  3KNV A;  5B77 A;  3O70 A;  1X4J A;  2MUM A;  1WEW A;  3O33 A;  3DPL R;  1MM2 A;  1JOC A;  4PTB A;  4WZ2 A;  5H1U A;  4S3O C;  4LKA A;  3HTK C;  2EOD A;  4YAX A;  4AVX A;  1DCQ A;  4LLB A;  2NAA A;  3H7H A;  5K3Q A;  5C11 A;  2EXU A;  5D1L B;  4A49 A;  2DSM A;  4TKP B;  4WA6 A;  3T7L A;  4BHW A;  3E2D A;  4XI1 A;  4C9Z A;  3ZPV E;  4CA1 A;  2VJF A;  5B79 A;  2CRR A;  1VD4 A;  1X4I A;  2XOZ A;  3O37 A;  3ZTG A;  4N4F A;  5G0F A;  3N9P A;  2VP7 A;  1V87 A;  1HYJ A;  2CKL A;  2OXQ C;  1WEO A;  3ZPV 1;  4Z0R A;  5FB1 A;  2MD8 C;  5AIU A;  2H0D A;  3L1X A;  2MA5 A;  2M1R A;  3LQJ A;  2D8U A;  2KR4 A;  1HYI A;  2I50 A;  5G05 B;  5H1V A;  5FER A;  2CSY A;  2LQ6 A;  3N9N A;  3FEH A;  4A4C A;  2VJF B;  2HYE D;  2YVR A;  2K17 A; 
#chains in the Genus database with same CATH homology
 2KKX A;  2P57 A;  3H7H A;  2L7P A;  2MKE A;  3LJU X;  2XOY A;  5K3Q A;  2E61 A;  3O47 A;  2XP0 A;  2EXU A;  2OWA A;  2CRW A;  2JUN A;  3E2D A;  3LVQ E;  2D8U A;  2RR4 A;  4O62 A;  4OGC A;  3DDT A;  2CSV A;  3FJU B;  5SVY A;  3Q1D A;  3DWD A;  3LDY A;  3M7K A;  2M13 A;  5SVX A;  4OGE A;  2LAU A;  3MDB C;  2CRR A;  2IQJ A;  2FD4 A;  4F1P A;  4Z0R A;  2B0O E;  2XOZ A;  5SVI A;  3LVR E;  3T9K A;  3FM8 C;  2KKY A;  3FEH A;  2YVR A;  3PLW A;  4Z0O A;  3SUB A;  4QQ4 A;  2FFW A;  2YRE A;  2JM3 A;  3KDE C;  3JUE A;  2CON A;  2XOC A;  5SVI B;  4H9D A;  2EGM A;  1DCQ A;  2DJA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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