3KDEC

Crystal structure of the thap domain from d. melanogaster p-element transposase in complex with its natural dna binding site
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
76
structure length
74
Chain Sequence
MKYCKFCCKAVTGVKLIHVPKCAIKRKLWEQSLGCSLGENSQICDTHFNDSQWKAAKGQTFKRRRLNADAVPSK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves.
pubmed doi rcsb
molecule tags Dna binding protein/dna
source organism Drosophila melanogaster
molecule keywords 5'-D(*GP*TP*TP*AP*AP*GP*(BRU)P*GP*GP*A)-3'
total genus 13
structure length 74
sequence length 76
ec nomenclature
pdb deposition date 2009-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF05485 THAP THAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.180 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Herpes Virus-1 3kdeC01
2JM3A 3KDEC 2LAUA
chains in the Genus database with same CATH superfamily
4YC9A 2LGVA 4ZUXU 1MM2A 2EGPA 2KWOA 3DDTA 3ZPV1 3C6WA 2VP7A 3DPLR 2L0BA 1LDKC 4C9ZA 2VJEA 3PHDA 2EODA 2G45A 2AN6A 2IQJA 1WEEA 2KWKA 1VD4A 2LV9A 5B78A 2JMIA 5SVYA 5H1TA 4LLBA 2E6SA 2MA6A 2L43A 4PPEA 5AITA 2QICA 2K1JA 2EGMA 2KR4A 1Z6UA 1RMDA 2FUIA 4YBSA 1XWHA 3ZVYA 3DQVR 5D1LB 2CSVA 2KIZA 2LAUA 2YURA 2BAYA 5D1KB 2CKLB 5SVIA 2LDRA 2YYRA 5B79A 2JMJA 3M7KA 2H0DA 4B7YC 3L1ZB 2YQMA 3I2DA 2CSYA 2CRRA 4YBTA 1WEWA 3O34A 3FL2A 1DVPA 2FFWA 2LXHC 2OWAA 2CKLA 3LVQE 2CONA 1WESA 3LDYA 2G43A 3LJUX 3U5MA 1WIMA 4MVTA 1WE9A 4NN2A 2VPBA 5EYAF 3V43A 4GNGA 4O64A 5FERA 4O62A 5K3QA 3ZPVE 4WZ0A 1DCQA 3HCSA 2FUUA 2VPDA 3LQJA 5KH9A 1N87A 1IYMA 2L5UA 2UZGA 3KDEC 3NG2A 1G25A 2MUMA 3MHHA 1LDJB 2MD7B 1WEVA 3FAOA 4YATA 3LQIA 1MBMA 3N9PA 5TABA 4FK5A 2YSMA 2KFTA 4FIPA 1HYJA 1JM7B 2KKXA 3LRQA 1FBVA 2ECVA 2KWJA 1FP0A 4UP0A 2MIQA 2YVRA 1MM3A 2M3HA 4A0CD 2F6JA 2Y1MA 3PLWA 4IC2A 3MDBC 3U5OA 3E2DA 2OXQC 4QF3A 2YSJA 2KGGA 4OGEA 5LCWB 3KV5A 2VJFA 4A4BA 2KKYA 4A4CA 3SUBA 2FD4A 2K4DA 2VPGA 2YHOA 5FEYA 4S3OB 4S3OC 4I7DA 4N3WA 2XOZA 2B0OE 5G0FA 3DWDA 2RR4A 5JG6A 3O33A 4CA1A 2I50A 3JUEA 2C2LA 2XOCA 5KH7A 1X4IA 5SVXA 5SVIB 3KV6A 2PUYA 4N4FA 2H0DB 2MNYA 3QZVA 2XP0A 5D1MB 4Z0RA 2LGKA 5H9MA 2LGGA 4V3KC 3KNVA 4P5OB 2QJ0A 5B8DA 2F42A 5FB1A 3SHBA 2EA6A 4Z0OA 4F52B 3FANA 2L75A 2RSDA 4UI9B 2NAAA 3SOUA 4CCGX 3HCTA 2XEUA 3C5KA 2DSMA 2IDAA 5C13A 1CHCA 5LKXA 1WILA 3ZVZB 5B77A 4L7XA 5KH3A 2PNXA 4LADB 3PUQA 4I7BA 4OGCA 4WZ3B 1VFYA 3M62A 5DINA 1WFKA 2C2VS 2D8SA 3EB5A 3SOXA 4F1PA 2RI7A 2ZETC 2ECNA 3ASLA 3O36A 2HDPA 3O70A 2DJAA 4TKPB 3HCUA 3U5PA 3LVRE 5J3XA 2LXPC 4I7CA 3N9LA 2D8UA 5TRBA 2E6RA 2HYED 3T9KA 1T1HA 1WEUA 2Y43A 3O7AA 4ZQLA 4BBQA 4GB0A 3RPGB 3RPGC 2VJFB 1X4JA 3N9QA 3M63A 5DKAA 2K16A 2CSZA 2QIZA 2YHNA 4R7EA 3VK6A 4AUQB 5LKTA 4Q6FA 2XB1A 3L11A 3FEHA 4WZ2A 3FJUB 1JOCA 1WENA 2L80A 3U5NA 5AIUA 1U6GB 1HYIA 2LRIC 2ECTA 1X4UA 3O37A 2Y1NA 4GNEA 3EB6A 3N9NA 2CRWA 5TDWA 2YU4A 4BHWA 4AYCB 1ZBDB 2M85A 4FO9A 2KYUA 3O35A 5G05B 5H1VA 1WGMA 3LQHA 1WEQA 4QF2A 2JM3A 2MKEA 3SOWA 4AP4A 3M99A 5LKUA 4LK9A 2VNFA 2YQLA 4L58A 3ZTGA 5LKZA 2JUNA 4AYCA 5I3LA 2LN0A 4W4UA 5FB0A 3GL6A 3T6RA 4YADA 5G04B 3HTKC 2CT2A 2KU3A 3N9MA 3PURA 3ZNIA 1Z60A 4XI1A 4IC3A 1K2FA 2M6MA 2ECIA 3L1XA 3KQIA 3ZYQA 4UP5A 2MA5A 2VPEA 2G6QA 3MHSA 2M13A 2JMDA 3H7HA 2E61A 3IHPA 2MNZA 2FSAA 2JRJA 2KREA 4MSXA 5H1UA 3Q1DA 1VYXA 2LQ6A 1V87A 2M1RA 3T7LA 1WEOA 4GNFA 1WEMA 2XOYA 4R2YA 4B86C 2DX8A 2MD8C 4X3GA 5B76A 2P57A 4WA6A 4A49A 3FM8C 4LKAA 4GNDA 3N9OA 2K17A 2YT5A 2ECWA 1BORA 2KE1A 2YW8A 2KWNA 4YABA 4R8PK 2ECJA 4PTBA 2F6NA 3GV4A 4LJNA 4AVXA 5B75A 4FJCA 1E4UA 2ECGA 2LGLA 4H9DA 3O47A 4YBMA 5C11A 4V3LC 4YAXA 1F62A 4ZDTA 2L7PA 2MT5A 3RTRB 1JM7A 4QQ4A 2YREA 1Z2QA 1WEPA 2KGIA 5TBNA 2VJEB 5TDRA 2YUCA 2EXUA
chains in the Genus database with same CATH topology
4Z0OA 2M13A 2CRRA 4OGCA 4O62A 2XOCA 5SVXA 4H9DA 5K3QA 5SVIB 2KKXA 4OGEA 2D8UA 2P57A 2JM3A 1DCQA 3FEHA 2MKEA 3O47A 3FJUB 3DDTA 3FM8C 4F1PA 3T9KA 3H7HA 2FFWA 2E61A 2KKYA 2OWAA 2XP0A 2EGMA 2L7PA 3SUBA 2FD4A 3LVQE 4Z0RA 2CONA 2CSVA 2JUNA 3Q1DA 3KDEC 2IQJA 2LAUA 3LDYA 2XOZA 4QQ4A 2B0OE 2DJAA 5SVIA 2YREA 2YVRA 3DWDA 3LJUX 2RR4A 3M7KA 2XOYA 3PLWA 2CRWA 3MDBC 3E2DA 5SVYA 3JUEA 3LVRE 2EXUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JM3 A;  3KDE C;  2LAU A; 
#chains in the Genus database with same CATH topology
 4YC9 A;  2LGV A;  4ZUX U;  1MM2 A;  2EGP A;  2KWO A;  3DDT A;  3ZPV 1;  3C6W A;  2VP7 A;  3DPL R;  2L0B A;  1LDK C;  4C9Z A;  2VJE A;  3PHD A;  2EOD A;  2G45 A;  2AN6 A;  2IQJ A;  1WEE A;  2KWK A;  1VD4 A;  2LV9 A;  5B78 A;  2JMI A;  5SVY A;  5H1T A;  4LLB A;  2E6S A;  2MA6 A;  2L43 A;  4PPE A;  5AIT A;  2QIC A;  2K1J A;  2EGM A;  2KR4 A;  1Z6U A;  1RMD A;  2FUI A;  4YBS A;  1XWH A;  3ZVY A;  3DQV R;  5D1L B;  2CSV A;  2KIZ A;  2LAU A;  2YUR A;  2BAY A;  5D1K B;  2CKL B;  5SVI A;  2LDR A;  2YYR A;  5B79 A;  2JMJ A;  3M7K A;  2H0D A;  4B7Y C;  3L1Z B;  2YQM A;  3I2D A;  2CSY A;  2CRR A;  4YBT A;  1WEW A;  3O34 A;  3FL2 A;  1DVP A;  2FFW A;  2LXH C;  2OWA A;  2CKL A;  3LVQ E;  2CON A;  1WES A;  3LDY A;  2G43 A;  3LJU X;  3U5M A;  1WIM A;  4MVT A;  1WE9 A;  4NN2 A;  2VPB A;  5EYA F;  3V43 A;  4GNG A;  4O64 A;  5FER A;  4O62 A;  5K3Q A;  3ZPV E;  4WZ0 A;  1DCQ A;  3HCS A;  2FUU A;  2VPD A;  3LQJ A;  5KH9 A;  1N87 A;  1IYM A;  2L5U A;  2UZG A;  3KDE C;  3NG2 A;  1G25 A;  2MUM A;  3MHH A;  1LDJ B;  2MD7 B;  1WEV A;  3FAO A;  4YAT A;  3LQI A;  1MBM A;  3N9P A;  5TAB A;  4FK5 A;  2YSM A;  2KFT A;  4FIP A;  1HYJ A;  1JM7 B;  2KKX A;  3LRQ A;  1FBV A;  2ECV A;  2KWJ A;  1FP0 A;  4UP0 A;  2MIQ A;  2YVR A;  1MM3 A;  2M3H A;  4A0C D;  2F6J A;  2Y1M A;  3PLW A;  4IC2 A;  3MDB C;  3U5O A;  3E2D A;  2OXQ C;  4QF3 A;  2YSJ A;  2KGG A;  4OGE A;  5LCW B;  3KV5 A;  2VJF A;  4A4B A;  2KKY A;  4A4C A;  3SUB A;  2FD4 A;  2K4D A;  2VPG A;  2YHO A;  5FEY A;  4S3O B;  4S3O C;  4I7D A;  4N3W A;  2XOZ A;  2B0O E;  5G0F A;  3DWD A;  2RR4 A;  5JG6 A;  3O33 A;  4CA1 A;  2I50 A;  3JUE A;  2C2L A;  2XOC A;  5KH7 A;  1X4I A;  5SVX A;  5SVI B;  3KV6 A;  2PUY A;  4N4F A;  2H0D B;  2MNY A;  3QZV A;  2XP0 A;  5D1M B;  4Z0R A;  2LGK A;  5H9M A;  2LGG A;  4V3K C;  3KNV A;  4P5O B;  2QJ0 A;  5B8D A;  2F42 A;  5FB1 A;  3SHB A;  2EA6 A;  4Z0O A;  4F52 B;  3FAN A;  2L75 A;  2RSD A;  4UI9 B;  2NAA A;  3SOU A;  4CCG X;  3HCT A;  2XEU A;  3C5K A;  2DSM A;  2IDA A;  5C13 A;  1CHC A;  5LKX A;  1WIL A;  3ZVZ B;  5B77 A;  4L7X A;  5KH3 A;  2PNX A;  4LAD B;  3PUQ A;  4I7B A;  4OGC A;  4WZ3 B;  1VFY A;  3M62 A;  5DIN A;  1WFK A;  2C2V S;  2D8S A;  3EB5 A;  3SOX A;  4F1P A;  2RI7 A;  2ZET C;  2ECN A;  3ASL A;  3O36 A;  2HDP A;  3O70 A;  2DJA A;  4TKP B;  3HCU A;  3U5P A;  3LVR E;  5J3X A;  2LXP C;  4I7C A;  3N9L A;  2D8U A;  5TRB A;  2E6R A;  2HYE D;  3T9K A;  1T1H A;  1WEU A;  2Y43 A;  3O7A A;  4ZQL A;  4BBQ A;  4GB0 A;  3RPG B;  3RPG C;  2VJF B;  1X4J A;  3N9Q A;  3M63 A;  5DKA A;  2K16 A;  2CSZ A;  2QIZ A;  2YHN A;  4R7E A;  3VK6 A;  4AUQ B;  5LKT A;  4Q6F A;  2XB1 A;  3L11 A;  3FEH A;  4WZ2 A;  3FJU B;  1JOC A;  1WEN A;  2L80 A;  3U5N A;  5AIU A;  1U6G B;  1HYI A;  2LRI C;  2ECT A;  1X4U A;  3O37 A;  2Y1N A;  4GNE A;  3EB6 A;  3N9N A;  2CRW A;  5TDW A;  2YU4 A;  4BHW A;  4AYC B;  1ZBD B;  2M85 A;  4FO9 A;  2KYU A;  3O35 A;  5G05 B;  5H1V A;  1WGM A;  3LQH A;  1WEQ A;  4QF2 A;  2JM3 A;  2MKE A;  3SOW A;  4AP4 A;  3M99 A;  5LKU A;  4LK9 A;  2VNF A;  2YQL A;  4L58 A;  3ZTG A;  5LKZ A;  2JUN A;  4AYC A;  5I3L A;  2LN0 A;  4W4U A;  5FB0 A;  3GL6 A;  3T6R A;  4YAD A;  5G04 B;  3HTK C;  2CT2 A;  2KU3 A;  3N9M A;  3PUR A;  3ZNI A;  1Z60 A;  4XI1 A;  4IC3 A;  1K2F A;  2M6M A;  2ECI A;  3L1X A;  3KQI A;  3ZYQ A;  4UP5 A;  2MA5 A;  2VPE A;  2G6Q A;  3MHS A;  2M13 A;  2JMD A;  3H7H A;  2E61 A;  3IHP A;  2MNZ A;  2FSA A;  2JRJ A;  2KRE A;  4MSX A;  5H1U A;  3Q1D A;  1VYX A;  2LQ6 A;  1V87 A;  2M1R A;  3T7L A;  1WEO A;  4GNF A;  1WEM A;  2XOY A;  4R2Y A;  4B86 C;  2DX8 A;  2MD8 C;  4X3G A;  5B76 A;  2P57 A;  4WA6 A;  4A49 A;  3FM8 C;  4LKA A;  4GND A;  3N9O A;  2K17 A;  2YT5 A;  2ECW A;  1BOR A;  2KE1 A;  2YW8 A;  2KWN A;  4YAB A;  4R8P K;  2ECJ A;  4PTB A;  2F6N A;  3GV4 A;  4LJN A;  4AVX A;  5B75 A;  4FJC A;  1E4U A;  2ECG A;  2LGL A;  4H9D A;  3O47 A;  4YBM A;  5C11 A;  4V3L C;  4YAX A;  1F62 A;  4ZDT A;  2L7P A;  2MT5 A;  3RTR B;  1JM7 A;  4QQ4 A;  2YRE A;  1Z2Q A;  1WEP A;  2KGI A;  5TBN A;  2VJE B;  5TDR A;  2YUC A;  2EXU A; 
#chains in the Genus database with same CATH homology
 4Z0O A;  2M13 A;  2CRR A;  4OGC A;  4O62 A;  2XOC A;  5SVX A;  4H9D A;  5K3Q A;  5SVI B;  2KKX A;  4OGE A;  2D8U A;  2P57 A;  2JM3 A;  1DCQ A;  3FEH A;  2MKE A;  3O47 A;  3FJU B;  3DDT A;  3FM8 C;  4F1P A;  3T9K A;  3H7H A;  2FFW A;  2E61 A;  2KKY A;  2OWA A;  2XP0 A;  2EGM A;  2L7P A;  3SUB A;  2FD4 A;  3LVQ E;  4Z0R A;  2CON A;  2CSV A;  2JUN A;  3Q1D A;  3KDE C;  2IQJ A;  2LAU A;  3LDY A;  2XOZ A;  4QQ4 A;  2B0O E;  2DJA A;  5SVI A;  2YRE A;  2YVR A;  3DWD A;  3LJU X;  2RR4 A;  3M7K A;  2XOY A;  3PLW A;  2CRW A;  3MDB C;  3E2D A;  5SVY A;  3JUE A;  3LVR E;  2EXU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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