3KDEC

Crystal structure of the thap domain from d. melanogaster p-element transposase in complex with its natural dna binding site
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
76
structure length
74
Chain Sequence
MKYCKFCCKAVTGVKLIHVPKCAIKRKLWEQSLGCSLGENSQICDTHFNDSQWKAAKGQTFKRRRLNADAVPSK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna binding protein/dna
source organism Drosophila melanogaster
publication title THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves.
pubmed doi rcsb
molecule keywords 5'-D(*GP*TP*TP*AP*AP*GP*(BRU)P*GP*GP*A)-3'
total genus 13
structure length 74
sequence length 76
ec nomenclature
pdb deposition date 2009-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF05485 THAP THAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.180 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Herpes Virus-1 3kdeC01
2JM3A 3KDEC 2LAUA
chains in the Genus database with same CATH superfamily
2K4DA 3HCUA 4MVTA 2EODA 2EXUA 5H1UA 4PPEA 2JRJA 2MD7B 2KKYA 4BHWA 5FEYA 2MKEA 2VP7A 4YBMA 2YU4A 2YSJA 3M62A 3U5OA 2FUUA 2LQ6A 3ZVZB 1WEQA 1CHCA 3E2DA 4YABA 5B78A 2KWOA 3N9NA 1MBMA 2G45A 2RSDA 5FERA 3L1XA 5DINA 2C2LA 5DKAA 1X4IA 2KIZA 3EB5A 4V3LC 3DWDA 3I2DA 1Z6UA 2JMJA 3O34A 2ECVA 3Q1DA 3ZPVE 2HDPA 1VD4A 3KQIA 2ECIA 1N87A 1WEUA 3LQHA 3SUBA 2G43A 3LJUX 3DDTA 2P57A 4R2YA 3H7HA 4UP5A 1FP0A 4LKAA 2XP0A 4R7EA 3ZPV1 3L11A 1X4JA 5G05B 4AUQB 1LDJB 5KH7A 1WIMA 2KGGA 5B8DA 5LKXA 3MHHA 2FFWA 4F1PA 3ZYQA 4FO9A 4N4FA 2YW8A 4TKPB 1JM7B 4GNDA 5G04B 1V87A 1F62A 3PURA 3DPLR 5AIUA 4N3WA 2KR4A 2MIQA 1IYMA 5B75A 3PLWA 4FK5A 3ZNIA 4LADB 4L7XA 2YQLA 2IDAA 4ZQLA 2B0OE 3N9MA 5SVIB 2DX8A 3MHSA 3LQJA 1FBVA 5B76A 3HTKC 2L0BA 2K17A 2K16A 4CA1A 4V3KC 2YUCA 5D1KB 1WESA 4ZDTA 4W4UA 4S3OC 1LDKC 3T6RA 3QZVA 2ZETC 4B86C 2LGGA 3V43A 3EB6A 2VJFB 2CRRA 3RTRB 5LCWB 1G25A 2PUYA 2UZGA 3U5NA 4YADA 2LXHC 5TDWA 3PUQA 1E4UA 3C6WA 3GL6A 2KE1A 1JM7A 2LGKA 1JOCA 1WEEA 2L7PA 2CSVA 2M13A 1WE9A 3FJUB 1T1HA 2D8SA 2MNZA 3KV5A 4AYCB 2KU3A 2EGMA 4OGCA 2LN0A 3MDBC 3KDEC 5AITA 1DCQA 2EA6A 2LGLA 2MA5A 4YBTA 5SVIA 5TRBA 4H9DA 4GB0A 2KWJA 3GV4A 2XEUA 3SOUA 5D1MB 2C2VS 2KFTA 5TABA 4F52B 3SHBA 2VPBA 2LV9A 2Y43A 2CKLB 4LJNA 2D8UA 2ECNA 2DJAA 2FSAA 3FAOA 2H0DB 2MNYA 2YHNA 5LKUA 4C9ZA 2JMDA 4A4CA 2VJFA 2QJ0A 2YURA 2KWKA 2CSZA 2FD4A 4PTBA 3FL2A 2XB1A 2IQJA 1WILA 1Z2QA 5EYAF 4UP0A 2YYRA 3JUEA 3T7LA 2L75A 2YHOA 3VK6A 2EGPA 4A0CD 2M3HA 4AYCA 1WEOA 2KREA 4Z0OA 2VPGA 2HYED 1WEMA 3O35A 2QIZA 2QICA 2F6JA 4YATA 2LXPC 3HCTA 1RMDA 2KKXA 4IC2A 2MA6A 2LAUA 2XOYA 3KNVA 2ECGA 2FUIA 5H1TA 2CKLA 4BBQA 3LVRE 4IC3A 4Z0RA 2H0DA 2XOCA 3RPGB 2MD8C 5D1LB 2VJEB 2VPDA 3M99A 1WEVA 2I50A 2AN6A 5KH3A 1WEWA 4B7YC 4OGEA 3N9LA 2RI7A 1MM2A 4QQ4A 4A49A 3LRQA 4XI1A 4YC9A 2ECJA 5SVXA 2Y1NA 3KV6A 5C13A 3O33A 3L1ZB 4P5OB 5SVYA 3O36A 4O62A 4QF3A 3C5KA 2KWNA 3SOWA 1WFKA 1HYIA 4WZ3B 2LGVA 2JMIA 1VFYA 4I7DA 2F6NA 3DQVR 3FANA 4WZ0A 5FB0A 3ZVYA 2PNXA 4GNFA 3T9KA 1Z60A 2LRIC 3O7AA 4FJCA 4A4BA 1VYXA 1DVPA 5JG6A 1XWHA 3LDYA 1X4UA 1WENA 3SOXA 2JUNA 2CT2A 4QF2A 2VJEA 4LLBA 4Q6FA 2VNFA 4R8PK 4MSXA 1MM3A 5FB1A 1WEPA 2YREA 4LK9A 2VPEA 5LKTA 4I7CA 3LQIA 2KYUA 5G0FA 2CONA 2YQMA 2CRWA 2MT5A 3ASLA 5C11A 5K3QA 2LDRA 3O37A 1U6GB 4O64A 4X3GA 3N9OA 3NG2A 2NAAA 3PHDA 2YSMA 4ZUXU 2ECTA 3U5PA 4FIPA 4YAXA 5KH9A 3FM8C 5I3LA 3FEHA 3IHPA 2K1JA 2MUMA 4AVXA 4L58A 2DSMA 2CSYA 5B79A 3N9QA 2L43A 1WGMA 1BORA 2BAYA 2E6RA 2L80A 3ZTGA 2KGIA 4UI9B 2M1RA 3HCSA 2JM3A 4CCGX 3N9PA 4WA6A 4NN2A 2YT5A 2OWAA 5J3XA 4S3OB 2L5UA 4GNEA 5TDRA 5H9MA 2F42A 5LKZA 5H1VA 4AP4A 2E61A 5B77A 1ZBDB 2YVRA 2G6QA 1HYJA 2M6MA 3O47A 3U5MA 2XOZA 3M63A 2RR4A 3O70A 4YBSA 4GNGA 2OXQC 4WZ2A 3M7KA 2M85A 5TBNA 3RPGC 2Y1MA 4I7BA 1K2FA 2ECWA 3LVQE 2E6SA
chains in the Genus database with same CATH topology
2CRWA 3H7HA 3LDYA 5SVIB 2IQJA 2EXUA 5K3QA 2CRRA 4OGEA 2XP0A 2KKXA 3JUEA 3LVQE 2EGMA 2E61A 4OGCA 2YVRA 3DWDA 2D8UA 2KKYA 2JUNA 3MDBC 2DJAA 4QQ4A 3KDEC 1DCQA 3O47A 2LAUA 2XOYA 3Q1DA 2MKEA 2XOZA 5SVIA 5SVXA 2RR4A 3FM8C 2JM3A 2YREA 3T9KA 4H9DA 3FEHA 4Z0OA 3E2DA 2L7PA 3PLWA 3M7KA 5SVYA 2OWAA 2FD4A 2FFWA 3LVRE 2CSVA 2M13A 4O62A 4Z0RA 3FJUB 2XOCA 3SUBA 4F1PA 2CONA 3LJUX 3DDTA 2B0OE 2P57A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JM3 A;  3KDE C;  2LAU A; 
#chains in the Genus database with same CATH topology
 2K4D A;  3HCU A;  4MVT A;  2EOD A;  2EXU A;  5H1U A;  4PPE A;  2JRJ A;  2MD7 B;  2KKY A;  4BHW A;  5FEY A;  2MKE A;  2VP7 A;  4YBM A;  2YU4 A;  2YSJ A;  3M62 A;  3U5O A;  2FUU A;  2LQ6 A;  3ZVZ B;  1WEQ A;  1CHC A;  3E2D A;  4YAB A;  5B78 A;  2KWO A;  3N9N A;  1MBM A;  2G45 A;  2RSD A;  5FER A;  3L1X A;  5DIN A;  2C2L A;  5DKA A;  1X4I A;  2KIZ A;  3EB5 A;  4V3L C;  3DWD A;  3I2D A;  1Z6U A;  2JMJ A;  3O34 A;  2ECV A;  3Q1D A;  3ZPV E;  2HDP A;  1VD4 A;  3KQI A;  2ECI A;  1N87 A;  1WEU A;  3LQH A;  3SUB A;  2G43 A;  3LJU X;  3DDT A;  2P57 A;  4R2Y A;  3H7H A;  4UP5 A;  1FP0 A;  4LKA A;  2XP0 A;  4R7E A;  3ZPV 1;  3L11 A;  1X4J A;  5G05 B;  4AUQ B;  1LDJ B;  5KH7 A;  1WIM A;  2KGG A;  5B8D A;  5LKX A;  3MHH A;  2FFW A;  4F1P A;  3ZYQ A;  4FO9 A;  4N4F A;  2YW8 A;  4TKP B;  1JM7 B;  4GND A;  5G04 B;  1V87 A;  1F62 A;  3PUR A;  3DPL R;  5AIU A;  4N3W A;  2KR4 A;  2MIQ A;  1IYM A;  5B75 A;  3PLW A;  4FK5 A;  3ZNI A;  4LAD B;  4L7X A;  2YQL A;  2IDA A;  4ZQL A;  2B0O E;  3N9M A;  5SVI B;  2DX8 A;  3MHS A;  3LQJ A;  1FBV A;  5B76 A;  3HTK C;  2L0B A;  2K17 A;  2K16 A;  4CA1 A;  4V3K C;  2YUC A;  5D1K B;  1WES A;  4ZDT A;  4W4U A;  4S3O C;  1LDK C;  3T6R A;  3QZV A;  2ZET C;  4B86 C;  2LGG A;  3V43 A;  3EB6 A;  2VJF B;  2CRR A;  3RTR B;  5LCW B;  1G25 A;  2PUY A;  2UZG A;  3U5N A;  4YAD A;  2LXH C;  5TDW A;  3PUQ A;  1E4U A;  3C6W A;  3GL6 A;  2KE1 A;  1JM7 A;  2LGK A;  1JOC A;  1WEE A;  2L7P A;  2CSV A;  2M13 A;  1WE9 A;  3FJU B;  1T1H A;  2D8S A;  2MNZ A;  3KV5 A;  4AYC B;  2KU3 A;  2EGM A;  4OGC A;  2LN0 A;  3MDB C;  3KDE C;  5AIT A;  1DCQ A;  2EA6 A;  2LGL A;  2MA5 A;  4YBT A;  5SVI A;  5TRB A;  4H9D A;  4GB0 A;  2KWJ A;  3GV4 A;  2XEU A;  3SOU A;  5D1M B;  2C2V S;  2KFT A;  5TAB A;  4F52 B;  3SHB A;  2VPB A;  2LV9 A;  2Y43 A;  2CKL B;  4LJN A;  2D8U A;  2ECN A;  2DJA A;  2FSA A;  3FAO A;  2H0D B;  2MNY A;  2YHN A;  5LKU A;  4C9Z A;  2JMD A;  4A4C A;  2VJF A;  2QJ0 A;  2YUR A;  2KWK A;  2CSZ A;  2FD4 A;  4PTB A;  3FL2 A;  2XB1 A;  2IQJ A;  1WIL A;  1Z2Q A;  5EYA F;  4UP0 A;  2YYR A;  3JUE A;  3T7L A;  2L75 A;  2YHO A;  3VK6 A;  2EGP A;  4A0C D;  2M3H A;  4AYC A;  1WEO A;  2KRE A;  4Z0O A;  2VPG A;  2HYE D;  1WEM A;  3O35 A;  2QIZ A;  2QIC A;  2F6J A;  4YAT A;  2LXP C;  3HCT A;  1RMD A;  2KKX A;  4IC2 A;  2MA6 A;  2LAU A;  2XOY A;  3KNV A;  2ECG A;  2FUI A;  5H1T A;  2CKL A;  4BBQ A;  3LVR E;  4IC3 A;  4Z0R A;  2H0D A;  2XOC A;  3RPG B;  2MD8 C;  5D1L B;  2VJE B;  2VPD A;  3M99 A;  1WEV A;  2I50 A;  2AN6 A;  5KH3 A;  1WEW A;  4B7Y C;  4OGE A;  3N9L A;  2RI7 A;  1MM2 A;  4QQ4 A;  4A49 A;  3LRQ A;  4XI1 A;  4YC9 A;  2ECJ A;  5SVX A;  2Y1N A;  3KV6 A;  5C13 A;  3O33 A;  3L1Z B;  4P5O B;  5SVY A;  3O36 A;  4O62 A;  4QF3 A;  3C5K A;  2KWN A;  3SOW A;  1WFK A;  1HYI A;  4WZ3 B;  2LGV A;  2JMI A;  1VFY A;  4I7D A;  2F6N A;  3DQV R;  3FAN A;  4WZ0 A;  5FB0 A;  3ZVY A;  2PNX A;  4GNF A;  3T9K A;  1Z60 A;  2LRI C;  3O7A A;  4FJC A;  4A4B A;  1VYX A;  1DVP A;  5JG6 A;  1XWH A;  3LDY A;  1X4U A;  1WEN A;  3SOX A;  2JUN A;  2CT2 A;  4QF2 A;  2VJE A;  4LLB A;  4Q6F A;  2VNF A;  4R8P K;  4MSX A;  1MM3 A;  5FB1 A;  1WEP A;  2YRE A;  4LK9 A;  2VPE A;  5LKT A;  4I7C A;  3LQI A;  2KYU A;  5G0F A;  2CON A;  2YQM A;  2CRW A;  2MT5 A;  3ASL A;  5C11 A;  5K3Q A;  2LDR A;  3O37 A;  1U6G B;  4O64 A;  4X3G A;  3N9O A;  3NG2 A;  2NAA A;  3PHD A;  2YSM A;  4ZUX U;  2ECT A;  3U5P A;  4FIP A;  4YAX A;  5KH9 A;  3FM8 C;  5I3L A;  3FEH A;  3IHP A;  2K1J A;  2MUM A;  4AVX A;  4L58 A;  2DSM A;  2CSY A;  5B79 A;  3N9Q A;  2L43 A;  1WGM A;  1BOR A;  2BAY A;  2E6R A;  2L80 A;  3ZTG A;  2KGI A;  4UI9 B;  2M1R A;  3HCS A;  2JM3 A;  4CCG X;  3N9P A;  4WA6 A;  4NN2 A;  2YT5 A;  2OWA A;  5J3X A;  4S3O B;  2L5U A;  4GNE A;  5TDR A;  5H9M A;  2F42 A;  5LKZ A;  5H1V A;  4AP4 A;  2E61 A;  5B77 A;  1ZBD B;  2YVR A;  2G6Q A;  1HYJ A;  2M6M A;  3O47 A;  3U5M A;  2XOZ A;  3M63 A;  2RR4 A;  3O70 A;  4YBS A;  4GNG A;  2OXQ C;  4WZ2 A;  3M7K A;  2M85 A;  5TBN A;  3RPG C;  2Y1M A;  4I7B A;  1K2F A;  2ECW A;  3LVQ E;  2E6S A; 
#chains in the Genus database with same CATH homology
 2CRW A;  3H7H A;  3LDY A;  5SVI B;  2IQJ A;  2EXU A;  5K3Q A;  2CRR A;  4OGE A;  2XP0 A;  2KKX A;  3JUE A;  3LVQ E;  2EGM A;  2E61 A;  4OGC A;  2YVR A;  3DWD A;  2D8U A;  2KKY A;  2JUN A;  3MDB C;  2DJA A;  4QQ4 A;  3KDE C;  1DCQ A;  3O47 A;  2LAU A;  2XOY A;  3Q1D A;  2MKE A;  2XOZ A;  5SVI A;  5SVX A;  2RR4 A;  3FM8 C;  2JM3 A;  2YRE A;  3T9K A;  4H9D A;  3FEH A;  4Z0O A;  3E2D A;  2L7P A;  3PLW A;  3M7K A;  5SVY A;  2OWA A;  2FD4 A;  2FFW A;  3LVR E;  2CSV A;  2M13 A;  4O62 A;  4Z0R A;  3FJU B;  2XOC A;  3SUB A;  4F1P A;  2CON A;  3LJU X;  3DDT A;  2B0O E;  2P57 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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