3DQVR

Structural insights into nedd8 activation of cullin-ring ligases: conformational control of conjugation
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
86
structure length
86
Chain Sequence
KRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords NEDD8
total genus 7
structure length 86
sequence length 86
chains with identical sequence Y
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2008-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF12678 zf-rbx1 RING-H2 zinc finger domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.10 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Zinc/RING finger domain, C3HC4 (zinc finger) 3dqvR00
3KNVA 1WEPA 2G45A 4YATA 2UZGA 5B77A 2KU3A 2YREA 5G0FA 1Z6UA 5LKTA 1WEQA 1N87A 1WENA 2AN6A 4ZDTA 2QIZA 3PHDA 2Y43A 3ZYQA 1JOCA 1JM7B 2L43A 3I2DA 4BHWA 5G05B 4B86C 3EB5A 4L7XA 5AIUA 4AP4A 5AITA 3U5MA 4A0CD 2LGLA 3RPGC 2MNZA 3L1ZB 2YQMA 4X3GA 2LXHC 5LKXA 1WEEA 2ECIA 2MT5A 2PUYA 1K2FA 2YU4A 5TBNA 2VPBA 2QJ0A 4YAXA 2LDRA 2M6MA 4IC2A 2MD7B 4GNEA 1WEWA 3N9LA 4YABA 4A4CA 3N9MA 2FUIA 3PUQA 2ECVA 4WZ0A 2YUCA 4O64A 5JG6A 3FL2A 5LKZA 3C6WA 4GB0A 4XI1A 4R8PK 3M63A 4UP5A 2EGPA 3HTKC 3O34A 2QICA 1MM3A 4PPEA 4LKAA 2ECTA 4YBTA 3GL6A 3KV5A 3O7AA 4S3OB 5FERA 3KV6A 1X4IA 3HCTA 2D8SA 2H0DB 2YHNA 3LRQA 1U6GB 3ZVZB 4LLBA 4PTBA 1WESA 2YT5A 2VNFA 2MA6A 4AYCB 2YSMA 2LGVA 4B7YC 1VFYA 3LQJA 3L11A 2KYUA 4YBSA 3C5KA 5KH7A 1WILA 2L0BA 2L5UA 4P5OB 1HYJA 3M62A 3MHSA 2KE1A 1Z2QA 2HDPA 4FO9A 2KWKA 2ECWA 4AUQB 5LCWB 2ECNA 3O37A 1WEVA 3N9PA 4CA1A 2M3HA 4AVXA 1ZBDB 1WEMA 2OXQC 4TKPB 2Y1NA 4LADB 5DINA 2EA6A 2MIQA 4I7BA 2JMJA 3EB6A 1Z60A 3U5NA 1X4UA 2CSZA 4Q6FA 4WZ3B 2F6JA 5G04B 5C11A 4QF3A 2ZETC 3U5PA 5FB1A 3T7LA 2KWOA 4UI9B 2KWNA 2XEUA 2LGKA 5I3LA 2VPEA 4FIPA 1LDJB 3ASLA 2CKLA 4GNFA 4F52B 1DVPA 3L1XA 1XWHA 3LQIA 1WEUA 2VPGA 3V43A 3VK6A 2FSAA 2MUMA 5TRBA 2VJFA 4V3KC 2HYED 2G6QA 3IHPA 4YBMA 2K4DA 2K16A 5FB0A 2VPDA 2KGGA 2IDAA 1G25A 2BAYA 5KH3A 1V87A 2YSJA 3KQIA 3O35A 2LV9A 4QF2A 5J3XA 5H1VA 1E4UA 1FBVA 4YC9A 1BORA 3O70A 2ECJA 4BBQA 2F42A 2LGGA 3N9NA 3RPGB 5DKAA 5KH9A 2CSYA 2M1RA 5TDWA 3HCSA 2RI7A 1FP0A 2KWJA 2FUUA 2VJEA 2KGIA 2C2VS 3LQHA 3M99A 3RTRB 2JMDA 1F62A 1VYXA 2Y1MA 5B8DA 1T1HA 1WEOA 4L58A 2JRJA 2RSDA 4R2YA 2PNXA 4LK9A 3DPLR 4R7EA 2G43A 2YURA 1X4JA 4S3OC 3ZNIA 2YYRA 3SOXA 5D1MB 3ZTGA 3N9QA 1CHCA 5D1LB 4ZQLA 2K17A 2JMIA 5FEYA 4WA6A 4A49A 4UP0A 2EODA 4V3LC 4CCGX 3U5OA 3PURA 2K1JA 2YW8A 4I7CA 1JM7A 2KREA 2ECGA 3SOWA 2YQLA 3ZPVE 5TABA 2MD8C 3O36A 1WFKA 2CKLB 4MSXA 2I50A 4A4BA 2MA5A 2LXPC 1HYIA 2KR4A 2YHOA 1WGMA 2VJFB 1IYMA 3HCUA 1WE9A 3ZPV1 3ZVYA 2LQ6A 5LKUA 3NG2A 4NN2A 3O33A 4WZ2A 2DX8A 2F6NA 5C13A 3SHBA 5H1TA 5B78A 2L80A 2LRIC 5H1UA 2E6SA 2C2LA 4YADA 4W4UA 4GNGA 2VP7A 4IC3A 4LJNA 4ZUXU 4FK5A 5B79A 4FJCA 4N3WA 2CT2A 5TDRA 5B76A 5H9MA 3T6RA 1RMDA 1LDKC 2L75A 3N9OA 1VD4A 2MNYA 4C9ZA 4N4FA 2M85A 3SOUA 5B75A 2VJEB 3MHHA 2LN0A 2NAAA 2KFTA 3DQVR 2KIZA 1WIMA 3QZVA 2E6RA 1MM2A 2XB1A 2H0DA 4I7DA 5D1KB 4GNDA 4MVTA 5EYAF 3GV4A 4AYCA
chains in the Genus database with same CATH superfamily
3KNVA 1WEPA 2G45A 4H9DA 4YATA 2UZGA 5B77A 2KU3A 2YREA 5G0FA 1Z6UA 2FD4A 5LKTA 1WEQA 2XOYA 1N87A 1WENA 2AN6A 4ZDTA 2QIZA 2JUNA 3PHDA 2Y43A 3ZYQA 1JOCA 1JM7B 2L43A 3I2DA 4BHWA 5G05B 2XOCA 4B86C 3EB5A 4L7XA 5AIUA 4AP4A 5AITA 3U5MA 2L7PA 4A0CD 2LGLA 3RPGC 3DDTA 2MNZA 3L1ZB 2YQMA 4X3GA 3FM8C 2LXHC 5LKXA 1WEEA 2ECIA 2MT5A 2PUYA 1K2FA 2YU4A 5TBNA 2VPBA 2QJ0A 3JUEA 4YAXA 2LDRA 2M6MA 3M7KA 4IC2A 2MD7B 4GNEA 1WEWA 3N9LA 4YABA 4A4CA 3N9MA 1MBMA 2FUIA 3PUQA 2MKEA 2ECVA 4WZ0A 2YUCA 4O64A 2P57A 5JG6A 3FL2A 5LKZA 3C6WA 4GB0A 4XI1A 4R8PK 3M63A 4UP5A 2OWAA 2EGPA 3HTKC 3O34A 2QICA 1MM3A 4PPEA 4LKAA 2ECTA 4YBTA 3GL6A 3KV5A 3O7AA 4S3OB 2D8UA 5FERA 3KV6A 1X4IA 2DJAA 3HCTA 3PLWA 2D8SA 2B0OE 2H0DB 2YHNA 3LRQA 1U6GB 3ZVZB 4LLBA 4PTBA 1WESA 2YT5A 2VNFA 2MA6A 4AYCB 2YSMA 2LGVA 4QQ4A 4Z0OA 4B7YC 1VFYA 3LQJA 3L11A 2KYUA 2CONA 4YBSA 3C5KA 5KH7A 1WILA 2L0BA 2L5UA 4P5OB 1HYJA 3M62A 3MHSA 2KE1A 1Z2QA 2HDPA 2IQJA 4FO9A 2KWKA 2ECWA 4AUQB 5LCWB 2ECNA 3O37A 1WEVA 2XP0A 3N9PA 4CA1A 2M3HA 4AVXA 1ZBDB 4OGCA 1WEMA 3Q1DA 2OXQC 3FEHA 4TKPB 2Y1NA 4LADB 2EA6A 5DINA 2MIQA 4I7BA 2JMJA 3EB6A 1Z60A 3U5NA 2CRRA 1X4UA 2CSZA 4Q6FA 4WZ3B 5SVYA 2F6JA 5G04B 5C11A 4QF3A 2XOZA 2KKXA 2ZETC 2RR4A 3U5PA 5FB1A 3T7LA 2KWOA 2EGMA 4UI9B 2KWNA 2XEUA 2EXUA 2LGKA 5I3LA 3SUBA 2VPEA 4FIPA 1LDJB 2FFWA 3ASLA 2CKLA 4GNFA 4F52B 1DVPA 3L1XA 3FANA 4F1PA 3FAOA 1XWHA 3LQIA 1WEUA 2VPGA 3V43A 3LVRE 3VK6A 2FSAA 2MUMA 5TRBA 2VJFA 4V3KC 2HYED 2G6QA 3IHPA 5K3QA 4Z0RA 4YBMA 2K4DA 2K16A 5FB0A 2VPDA 2KGGA 2IDAA 1G25A 2BAYA 5KH3A 1V87A 5SVXA 2YSJA 3KQIA 3E2DA 3O35A 2LV9A 4QF2A 5J3XA 5H1VA 3MDBC 1E4UA 1FBVA 4YC9A 1BORA 3O70A 2ECJA 4BBQA 2F42A 2LGGA 3N9NA 3KDEC 3RPGB 5DKAA 5KH9A 2CSYA 2M1RA 5TDWA 3HCSA 2RI7A 1FP0A 2KWJA 2FUUA 5SVIA 2VJEA 2KGIA 3FJUB 2C2VS 3LQHA 2YVRA 3M99A 3RTRB 2JMDA 1F62A 1VYXA 2Y1MA 2DSMA 5B8DA 1T1HA 3H7HA 1WEOA 2CRWA 4L58A 2JRJA 2RSDA 4R2YA 2PNXA 4LK9A 3DPLR 2CSVA 4R7EA 2G43A 2YURA 1X4JA 4S3OC 3ZNIA 2YYRA 3SOXA 5D1MB 3ZTGA 3N9QA 1CHCA 5D1LB 4ZQLA 2K17A 2JMIA 5FEYA 4WA6A 4A49A 4UP0A 2EODA 4V3LC 4CCGX 3U5OA 3PURA 2K1JA 2YW8A 4I7CA 1JM7A 2KREA 2ECGA 3SOWA 2YQLA 3ZPVE 5TABA 2MD8C 3O36A 1WFKA 2CKLB 3LVQE 4MSXA 2I50A 4A4BA 2LAUA 3DWDA 2MA5A 2LXPC 1HYIA 2KR4A 2YHOA 1WGMA 2VJFB 1IYMA 3HCUA 1WE9A 3ZPV1 3ZVYA 2LQ6A 4O62A 5LKUA 3NG2A 4NN2A 3O33A 4WZ2A 2DX8A 2F6NA 5C13A 3T9KA 2M13A 2KKYA 3SHBA 5H1TA 5B78A 2L80A 2LRIC 5H1UA 2E6SA 2C2LA 4YADA 4W4UA 1DCQA 4GNGA 2VP7A 4IC3A 4LJNA 4ZUXU 4FK5A 5B79A 4FJCA 4N3WA 2CT2A 5TDRA 5B76A 5H9MA 3T6RA 1RMDA 1LDKC 2JM3A 2L75A 3N9OA 3LDYA 3LJUX 1VD4A 3O47A 2MNYA 4C9ZA 4N4FA 2M85A 3SOUA 5B75A 5SVIB 2VJEB 3MHHA 2LN0A 2E61A 2NAAA 2KFTA 3DQVR 2KIZA 1WIMA 3QZVA 4OGEA 2E6RA 1MM2A 2XB1A 2H0DA 4I7DA 5D1KB 4GNDA 4MVTA 5EYAF 3GV4A 4AYCA
chains in the Genus database with same CATH topology
3KNVA 1WEPA 2G45A 4YATA 2UZGA 5B77A 2KU3A 2YREA 5G0FA 1Z6UA 5LKTA 1WEQA 1N87A 1WENA 2AN6A 4ZDTA 2QIZA 3PHDA 2Y43A 3ZYQA 1JOCA 1JM7B 2L43A 3I2DA 4BHWA 5G05B 4B86C 3EB5A 4L7XA 5AIUA 4AP4A 5AITA 3U5MA 4A0CD 2LGLA 3RPGC 2MNZA 3L1ZB 2YQMA 4X3GA 2LXHC 5LKXA 1WEEA 2ECIA 2MT5A 2PUYA 1K2FA 2YU4A 5TBNA 2VPBA 2QJ0A 4YAXA 2LDRA 2M6MA 4IC2A 2MD7B 4GNEA 1WEWA 3N9LA 4YABA 4A4CA 3N9MA 2FUIA 3PUQA 2ECVA 4WZ0A 2YUCA 4O64A 5JG6A 3FL2A 5LKZA 3C6WA 4GB0A 4XI1A 4R8PK 3M63A 4UP5A 2EGPA 3HTKC 3O34A 2QICA 1MM3A 4PPEA 4LKAA 2ECTA 4YBTA 3GL6A 3KV5A 3O7AA 4S3OB 5FERA 3KV6A 1X4IA 3HCTA 2D8SA 2H0DB 2YHNA 3LRQA 1U6GB 3ZVZB 4LLBA 4PTBA 1WESA 2YT5A 2VNFA 2MA6A 4AYCB 2YSMA 2LGVA 4B7YC 1VFYA 3LQJA 3L11A 2KYUA 4YBSA 3C5KA 5KH7A 1WILA 2L0BA 2L5UA 4P5OB 1HYJA 3M62A 3MHSA 2KE1A 1Z2QA 2HDPA 4FO9A 2KWKA 2ECWA 4AUQB 5LCWB 2ECNA 3O37A 1WEVA 3N9PA 4CA1A 2M3HA 4AVXA 1ZBDB 1WEMA 2OXQC 4TKPB 2Y1NA 4LADB 5DINA 2EA6A 2MIQA 4I7BA 2JMJA 3EB6A 1Z60A 3U5NA 1X4UA 2CSZA 4Q6FA 4WZ3B 2F6JA 5G04B 5C11A 4QF3A 2ZETC 3U5PA 5FB1A 3T7LA 2KWOA 4UI9B 2KWNA 2XEUA 2LGKA 5I3LA 2VPEA 4FIPA 1LDJB 3ASLA 2CKLA 4GNFA 4F52B 1DVPA 3L1XA 1XWHA 3LQIA 1WEUA 2VPGA 3V43A 3VK6A 2FSAA 2MUMA 5TRBA 2VJFA 4V3KC 2HYED 2G6QA 3IHPA 4YBMA 2K4DA 2K16A 5FB0A 2VPDA 2KGGA 2IDAA 1G25A 2BAYA 5KH3A 1V87A 2YSJA 3KQIA 3O35A 2LV9A 4QF2A 5J3XA 5H1VA 1E4UA 1FBVA 4YC9A 1BORA 3O70A 2ECJA 4BBQA 2F42A 2LGGA 3N9NA 3RPGB 5DKAA 5KH9A 2CSYA 2M1RA 5TDWA 3HCSA 2RI7A 1FP0A 2KWJA 2FUUA 2VJEA 2KGIA 2C2VS 3LQHA 3M99A 3RTRB 2JMDA 1F62A 1VYXA 2Y1MA 5B8DA 1T1HA 1WEOA 4L58A 2JRJA 2RSDA 4R2YA 2PNXA 4LK9A 3DPLR 4R7EA 2G43A 2YURA 1X4JA 4S3OC 3ZNIA 2YYRA 3SOXA 5D1MB 3ZTGA 3N9QA 1CHCA 5D1LB 4ZQLA 2K17A 2JMIA 5FEYA 4WA6A 4A49A 4UP0A 2EODA 4V3LC 4CCGX 3U5OA 3PURA 2K1JA 2YW8A 4I7CA 1JM7A 2KREA 2ECGA 3SOWA 2YQLA 3ZPVE 5TABA 2MD8C 3O36A 1WFKA 2CKLB 4MSXA 2I50A 4A4BA 2MA5A 2LXPC 1HYIA 2KR4A 2YHOA 1WGMA 2VJFB 1IYMA 3HCUA 1WE9A 3ZPV1 3ZVYA 2LQ6A 5LKUA 3NG2A 4NN2A 3O33A 4WZ2A 2DX8A 2F6NA 5C13A 3SHBA 5H1TA 5B78A 2L80A 2LRIC 5H1UA 2E6SA 2C2LA 4YADA 4W4UA 4GNGA 2VP7A 4IC3A 4LJNA 4ZUXU 4FK5A 5B79A 4FJCA 4N3WA 2CT2A 5TDRA 5B76A 5H9MA 3T6RA 1RMDA 1LDKC 2L75A 3N9OA 1VD4A 2MNYA 4C9ZA 4N4FA 2M85A 3SOUA 5B75A 2VJEB 3MHHA 2LN0A 2NAAA 2KFTA 3DQVR 2KIZA 1WIMA 3QZVA 2E6RA 1MM2A 2XB1A 2H0DA 4I7DA 5D1KB 4GNDA 4MVTA 5EYAF 3GV4A 4AYCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KNV A;  1WEP A;  2G45 A;  4YAT A;  2UZG A;  5B77 A;  2KU3 A;  2YRE A;  5G0F A;  1Z6U A;  5LKT A;  1WEQ A;  1N87 A;  1WEN A;  2AN6 A;  4ZDT A;  2QIZ A;  3PHD A;  2Y43 A;  3ZYQ A;  1JOC A;  1JM7 B;  2L43 A;  3I2D A;  4BHW A;  5G05 B;  4B86 C;  3EB5 A;  4L7X A;  5AIU A;  4AP4 A;  5AIT A;  3U5M A;  4A0C D;  2LGL A;  3RPG C;  2MNZ A;  3L1Z B;  2YQM A;  4X3G A;  2LXH C;  5LKX A;  1WEE A;  2ECI A;  2MT5 A;  2PUY A;  1K2F A;  2YU4 A;  5TBN A;  2VPB A;  2QJ0 A;  4YAX A;  2LDR A;  2M6M A;  4IC2 A;  2MD7 B;  4GNE A;  1WEW A;  3N9L A;  4YAB A;  4A4C A;  3N9M A;  2FUI A;  3PUQ A;  2ECV A;  4WZ0 A;  2YUC A;  4O64 A;  5JG6 A;  3FL2 A;  5LKZ A;  3C6W A;  4GB0 A;  4XI1 A;  4R8P K;  3M63 A;  4UP5 A;  2EGP A;  3HTK C;  3O34 A;  2QIC A;  1MM3 A;  4PPE A;  4LKA A;  2ECT A;  4YBT A;  3GL6 A;  3KV5 A;  3O7A A;  4S3O B;  5FER A;  3KV6 A;  1X4I A;  3HCT A;  2D8S A;  2H0D B;  2YHN A;  3LRQ A;  1U6G B;  3ZVZ B;  4LLB A;  4PTB A;  1WES A;  2YT5 A;  2VNF A;  2MA6 A;  4AYC B;  2YSM A;  2LGV A;  4B7Y C;  1VFY A;  3LQJ A;  3L11 A;  2KYU A;  4YBS A;  3C5K A;  5KH7 A;  1WIL A;  2L0B A;  2L5U A;  4P5O B;  1HYJ A;  3M62 A;  3MHS A;  2KE1 A;  1Z2Q A;  2HDP A;  4FO9 A;  2KWK A;  2ECW A;  4AUQ B;  5LCW B;  2ECN A;  3O37 A;  1WEV A;  3N9P A;  4CA1 A;  2M3H A;  4AVX A;  1ZBD B;  1WEM A;  2OXQ C;  4TKP B;  2Y1N A;  4LAD B;  5DIN A;  2EA6 A;  2MIQ A;  4I7B A;  2JMJ A;  3EB6 A;  1Z60 A;  3U5N A;  1X4U A;  2CSZ A;  4Q6F A;  4WZ3 B;  2F6J A;  5G04 B;  5C11 A;  4QF3 A;  2ZET C;  3U5P A;  5FB1 A;  3T7L A;  2KWO A;  4UI9 B;  2KWN A;  2XEU A;  2LGK A;  5I3L A;  2VPE A;  4FIP A;  1LDJ B;  3ASL A;  2CKL A;  4GNF A;  4F52 B;  1DVP A;  3L1X A;  1XWH A;  3LQI A;  1WEU A;  2VPG A;  3V43 A;  3VK6 A;  2FSA A;  2MUM A;  5TRB A;  2VJF A;  4V3K C;  2HYE D;  2G6Q A;  3IHP A;  4YBM A;  2K4D A;  2K16 A;  5FB0 A;  2VPD A;  2KGG A;  2IDA A;  1G25 A;  2BAY A;  5KH3 A;  1V87 A;  2YSJ A;  3KQI A;  3O35 A;  2LV9 A;  4QF2 A;  5J3X A;  5H1V A;  1E4U A;  1FBV A;  4YC9 A;  1BOR A;  3O70 A;  2ECJ A;  4BBQ A;  2F42 A;  2LGG A;  3N9N A;  3RPG B;  5DKA A;  5KH9 A;  2CSY A;  2M1R A;  5TDW A;  3HCS A;  2RI7 A;  1FP0 A;  2KWJ A;  2FUU A;  2VJE A;  2KGI A;  2C2V S;  3LQH A;  3M99 A;  3RTR B;  2JMD A;  1F62 A;  1VYX A;  2Y1M A;  5B8D A;  1T1H A;  1WEO A;  4L58 A;  2JRJ A;  2RSD A;  4R2Y A;  2PNX A;  4LK9 A;  3DPL R;  4R7E A;  2G43 A;  2YUR A;  1X4J A;  4S3O C;  3ZNI A;  2YYR A;  3SOX A;  5D1M B;  3ZTG A;  3N9Q A;  1CHC A;  5D1L B;  4ZQL A;  2K17 A;  2JMI A;  5FEY A;  4WA6 A;  4A49 A;  4UP0 A;  2EOD A;  4V3L C;  4CCG X;  3U5O A;  3PUR A;  2K1J A;  2YW8 A;  4I7C A;  1JM7 A;  2KRE A;  2ECG A;  3SOW A;  2YQL A;  3ZPV E;  5TAB A;  2MD8 C;  3O36 A;  1WFK A;  2CKL B;  4MSX A;  2I50 A;  4A4B A;  2MA5 A;  2LXP C;  1HYI A;  2KR4 A;  2YHO A;  1WGM A;  2VJF B;  1IYM A;  3HCU A;  1WE9 A;  3ZPV 1;  3ZVY A;  2LQ6 A;  5LKU A;  3NG2 A;  4NN2 A;  3O33 A;  4WZ2 A;  2DX8 A;  2F6N A;  5C13 A;  3SHB A;  5H1T A;  5B78 A;  2L80 A;  2LRI C;  5H1U A;  2E6S A;  2C2L A;  4YAD A;  4W4U A;  4GNG A;  2VP7 A;  4IC3 A;  4LJN A;  4ZUX U;  4FK5 A;  5B79 A;  4FJC A;  4N3W A;  2CT2 A;  5TDR A;  5B76 A;  5H9M A;  3T6R A;  1RMD A;  1LDK C;  2L75 A;  3N9O A;  1VD4 A;  2MNY A;  4C9Z A;  4N4F A;  2M85 A;  3SOU A;  5B75 A;  2VJE B;  3MHH A;  2LN0 A;  2NAA A;  2KFT A;  3DQV R;  2KIZ A;  1WIM A;  3QZV A;  2E6R A;  1MM2 A;  2XB1 A;  2H0D A;  4I7D A;  5D1K B;  4GND A;  4MVT A;  5EYA F;  3GV4 A;  4AYC A; 
#chains in the Genus database with same CATH topology
 3KNV A;  1WEP A;  2G45 A;  4H9D A;  4YAT A;  2UZG A;  5B77 A;  2KU3 A;  2YRE A;  5G0F A;  1Z6U A;  2FD4 A;  5LKT A;  1WEQ A;  2XOY A;  1N87 A;  1WEN A;  2AN6 A;  4ZDT A;  2QIZ A;  2JUN A;  3PHD A;  2Y43 A;  3ZYQ A;  1JOC A;  1JM7 B;  2L43 A;  3I2D A;  4BHW A;  5G05 B;  2XOC A;  4B86 C;  3EB5 A;  4L7X A;  5AIU A;  4AP4 A;  5AIT A;  3U5M A;  2L7P A;  4A0C D;  2LGL A;  3RPG C;  3DDT A;  2MNZ A;  3L1Z B;  2YQM A;  4X3G A;  3FM8 C;  2LXH C;  5LKX A;  1WEE A;  2ECI A;  2MT5 A;  2PUY A;  1K2F A;  2YU4 A;  5TBN A;  2VPB A;  2QJ0 A;  3JUE A;  4YAX A;  2LDR A;  2M6M A;  3M7K A;  4IC2 A;  2MD7 B;  4GNE A;  1WEW A;  3N9L A;  4YAB A;  4A4C A;  3N9M A;  1MBM A;  2FUI A;  3PUQ A;  2MKE A;  2ECV A;  4WZ0 A;  2YUC A;  4O64 A;  2P57 A;  5JG6 A;  3FL2 A;  5LKZ A;  3C6W A;  4GB0 A;  4XI1 A;  4R8P K;  3M63 A;  4UP5 A;  2OWA A;  2EGP A;  3HTK C;  3O34 A;  2QIC A;  1MM3 A;  4PPE A;  4LKA A;  2ECT A;  4YBT A;  3GL6 A;  3KV5 A;  3O7A A;  4S3O B;  2D8U A;  5FER A;  3KV6 A;  1X4I A;  2DJA A;  3HCT A;  3PLW A;  2D8S A;  2B0O E;  2H0D B;  2YHN A;  3LRQ A;  1U6G B;  3ZVZ B;  4LLB A;  4PTB A;  1WES A;  2YT5 A;  2VNF A;  2MA6 A;  4AYC B;  2YSM A;  2LGV A;  4QQ4 A;  4Z0O A;  4B7Y C;  1VFY A;  3LQJ A;  3L11 A;  2KYU A;  2CON A;  4YBS A;  3C5K A;  5KH7 A;  1WIL A;  2L0B A;  2L5U A;  4P5O B;  1HYJ A;  3M62 A;  3MHS A;  2KE1 A;  1Z2Q A;  2HDP A;  2IQJ A;  4FO9 A;  2KWK A;  2ECW A;  4AUQ B;  5LCW B;  2ECN A;  3O37 A;  1WEV A;  2XP0 A;  3N9P A;  4CA1 A;  2M3H A;  4AVX A;  1ZBD B;  4OGC A;  1WEM A;  3Q1D A;  2OXQ C;  3FEH A;  4TKP B;  2Y1N A;  4LAD B;  2EA6 A;  5DIN A;  2MIQ A;  4I7B A;  2JMJ A;  3EB6 A;  1Z60 A;  3U5N A;  2CRR A;  1X4U A;  2CSZ A;  4Q6F A;  4WZ3 B;  5SVY A;  2F6J A;  5G04 B;  5C11 A;  4QF3 A;  2XOZ A;  2KKX A;  2ZET C;  2RR4 A;  3U5P A;  5FB1 A;  3T7L A;  2KWO A;  2EGM A;  4UI9 B;  2KWN A;  2XEU A;  2EXU A;  2LGK A;  5I3L A;  3SUB A;  2VPE A;  4FIP A;  1LDJ B;  2FFW A;  3ASL A;  2CKL A;  4GNF A;  4F52 B;  1DVP A;  3L1X A;  3FAN A;  4F1P A;  3FAO A;  1XWH A;  3LQI A;  1WEU A;  2VPG A;  3V43 A;  3LVR E;  3VK6 A;  2FSA A;  2MUM A;  5TRB A;  2VJF A;  4V3K C;  2HYE D;  2G6Q A;  3IHP A;  5K3Q A;  4Z0R A;  4YBM A;  2K4D A;  2K16 A;  5FB0 A;  2VPD A;  2KGG A;  2IDA A;  1G25 A;  2BAY A;  5KH3 A;  1V87 A;  5SVX A;  2YSJ A;  3KQI A;  3E2D A;  3O35 A;  2LV9 A;  4QF2 A;  5J3X A;  5H1V A;  3MDB C;  1E4U A;  1FBV A;  4YC9 A;  1BOR A;  3O70 A;  2ECJ A;  4BBQ A;  2F42 A;  2LGG A;  3N9N A;  3KDE C;  3RPG B;  5DKA A;  5KH9 A;  2CSY A;  2M1R A;  5TDW A;  3HCS A;  2RI7 A;  1FP0 A;  2KWJ A;  2FUU A;  5SVI A;  2VJE A;  2KGI A;  3FJU B;  2C2V S;  3LQH A;  2YVR A;  3M99 A;  3RTR B;  2JMD A;  1F62 A;  1VYX A;  2Y1M A;  2DSM A;  5B8D A;  1T1H A;  3H7H A;  1WEO A;  2CRW A;  4L58 A;  2JRJ A;  2RSD A;  4R2Y A;  2PNX A;  4LK9 A;  3DPL R;  2CSV A;  4R7E A;  2G43 A;  2YUR A;  1X4J A;  4S3O C;  3ZNI A;  2YYR A;  3SOX A;  5D1M B;  3ZTG A;  3N9Q A;  1CHC A;  5D1L B;  4ZQL A;  2K17 A;  2JMI A;  5FEY A;  4WA6 A;  4A49 A;  4UP0 A;  2EOD A;  4V3L C;  4CCG X;  3U5O A;  3PUR A;  2K1J A;  2YW8 A;  4I7C A;  1JM7 A;  2KRE A;  2ECG A;  3SOW A;  2YQL A;  3ZPV E;  5TAB A;  2MD8 C;  3O36 A;  1WFK A;  2CKL B;  3LVQ E;  4MSX A;  2I50 A;  4A4B A;  2LAU A;  3DWD A;  2MA5 A;  2LXP C;  1HYI A;  2KR4 A;  2YHO A;  1WGM A;  2VJF B;  1IYM A;  3HCU A;  1WE9 A;  3ZPV 1;  3ZVY A;  2LQ6 A;  4O62 A;  5LKU A;  3NG2 A;  4NN2 A;  3O33 A;  4WZ2 A;  2DX8 A;  2F6N A;  5C13 A;  3T9K A;  2M13 A;  2KKY A;  3SHB A;  5H1T A;  5B78 A;  2L80 A;  2LRI C;  5H1U A;  2E6S A;  2C2L A;  4YAD A;  4W4U A;  1DCQ A;  4GNG A;  2VP7 A;  4IC3 A;  4LJN A;  4ZUX U;  4FK5 A;  5B79 A;  4FJC A;  4N3W A;  2CT2 A;  5TDR A;  5B76 A;  5H9M A;  3T6R A;  1RMD A;  1LDK C;  2JM3 A;  2L75 A;  3N9O A;  3LDY A;  3LJU X;  1VD4 A;  3O47 A;  2MNY A;  4C9Z A;  4N4F A;  2M85 A;  3SOU A;  5B75 A;  5SVI B;  2VJE B;  3MHH A;  2LN0 A;  2E61 A;  2NAA A;  2KFT A;  3DQV R;  2KIZ A;  1WIM A;  3QZV A;  4OGE A;  2E6R A;  1MM2 A;  2XB1 A;  2H0D A;  4I7D A;  5D1K B;  4GND A;  4MVT A;  5EYA F;  3GV4 A;  4AYC A; 
#chains in the Genus database with same CATH homology
 3KNV A;  1WEP A;  2G45 A;  4YAT A;  2UZG A;  5B77 A;  2KU3 A;  2YRE A;  5G0F A;  1Z6U A;  5LKT A;  1WEQ A;  1N87 A;  1WEN A;  2AN6 A;  4ZDT A;  2QIZ A;  3PHD A;  2Y43 A;  3ZYQ A;  1JOC A;  1JM7 B;  2L43 A;  3I2D A;  4BHW A;  5G05 B;  4B86 C;  3EB5 A;  4L7X A;  5AIU A;  4AP4 A;  5AIT A;  3U5M A;  4A0C D;  2LGL A;  3RPG C;  2MNZ A;  3L1Z B;  2YQM A;  4X3G A;  2LXH C;  5LKX A;  1WEE A;  2ECI A;  2MT5 A;  2PUY A;  1K2F A;  2YU4 A;  5TBN A;  2VPB A;  2QJ0 A;  4YAX A;  2LDR A;  2M6M A;  4IC2 A;  2MD7 B;  4GNE A;  1WEW A;  3N9L A;  4YAB A;  4A4C A;  3N9M A;  2FUI A;  3PUQ A;  2ECV A;  4WZ0 A;  2YUC A;  4O64 A;  5JG6 A;  3FL2 A;  5LKZ A;  3C6W A;  4GB0 A;  4XI1 A;  4R8P K;  3M63 A;  4UP5 A;  2EGP A;  3HTK C;  3O34 A;  2QIC A;  1MM3 A;  4PPE A;  4LKA A;  2ECT A;  4YBT A;  3GL6 A;  3KV5 A;  3O7A A;  4S3O B;  5FER A;  3KV6 A;  1X4I A;  3HCT A;  2D8S A;  2H0D B;  2YHN A;  3LRQ A;  1U6G B;  3ZVZ B;  4LLB A;  4PTB A;  1WES A;  2YT5 A;  2VNF A;  2MA6 A;  4AYC B;  2YSM A;  2LGV A;  4B7Y C;  1VFY A;  3LQJ A;  3L11 A;  2KYU A;  4YBS A;  3C5K A;  5KH7 A;  1WIL A;  2L0B A;  2L5U A;  4P5O B;  1HYJ A;  3M62 A;  3MHS A;  2KE1 A;  1Z2Q A;  2HDP A;  4FO9 A;  2KWK A;  2ECW A;  4AUQ B;  5LCW B;  2ECN A;  3O37 A;  1WEV A;  3N9P A;  4CA1 A;  2M3H A;  4AVX A;  1ZBD B;  1WEM A;  2OXQ C;  4TKP B;  2Y1N A;  4LAD B;  5DIN A;  2EA6 A;  2MIQ A;  4I7B A;  2JMJ A;  3EB6 A;  1Z60 A;  3U5N A;  1X4U A;  2CSZ A;  4Q6F A;  4WZ3 B;  2F6J A;  5G04 B;  5C11 A;  4QF3 A;  2ZET C;  3U5P A;  5FB1 A;  3T7L A;  2KWO A;  4UI9 B;  2KWN A;  2XEU A;  2LGK A;  5I3L A;  2VPE A;  4FIP A;  1LDJ B;  3ASL A;  2CKL A;  4GNF A;  4F52 B;  1DVP A;  3L1X A;  1XWH A;  3LQI A;  1WEU A;  2VPG A;  3V43 A;  3VK6 A;  2FSA A;  2MUM A;  5TRB A;  2VJF A;  4V3K C;  2HYE D;  2G6Q A;  3IHP A;  4YBM A;  2K4D A;  2K16 A;  5FB0 A;  2VPD A;  2KGG A;  2IDA A;  1G25 A;  2BAY A;  5KH3 A;  1V87 A;  2YSJ A;  3KQI A;  3O35 A;  2LV9 A;  4QF2 A;  5J3X A;  5H1V A;  1E4U A;  1FBV A;  4YC9 A;  1BOR A;  3O70 A;  2ECJ A;  4BBQ A;  2F42 A;  2LGG A;  3N9N A;  3RPG B;  5DKA A;  5KH9 A;  2CSY A;  2M1R A;  5TDW A;  3HCS A;  2RI7 A;  1FP0 A;  2KWJ A;  2FUU A;  2VJE A;  2KGI A;  2C2V S;  3LQH A;  3M99 A;  3RTR B;  2JMD A;  1F62 A;  1VYX A;  2Y1M A;  5B8D A;  1T1H A;  1WEO A;  4L58 A;  2JRJ A;  2RSD A;  4R2Y A;  2PNX A;  4LK9 A;  3DPL R;  4R7E A;  2G43 A;  2YUR A;  1X4J A;  4S3O C;  3ZNI A;  2YYR A;  3SOX A;  5D1M B;  3ZTG A;  3N9Q A;  1CHC A;  5D1L B;  4ZQL A;  2K17 A;  2JMI A;  5FEY A;  4WA6 A;  4A49 A;  4UP0 A;  2EOD A;  4V3L C;  4CCG X;  3U5O A;  3PUR A;  2K1J A;  2YW8 A;  4I7C A;  1JM7 A;  2KRE A;  2ECG A;  3SOW A;  2YQL A;  3ZPV E;  5TAB A;  2MD8 C;  3O36 A;  1WFK A;  2CKL B;  4MSX A;  2I50 A;  4A4B A;  2MA5 A;  2LXP C;  1HYI A;  2KR4 A;  2YHO A;  1WGM A;  2VJF B;  1IYM A;  3HCU A;  1WE9 A;  3ZPV 1;  3ZVY A;  2LQ6 A;  5LKU A;  3NG2 A;  4NN2 A;  3O33 A;  4WZ2 A;  2DX8 A;  2F6N A;  5C13 A;  3SHB A;  5H1T A;  5B78 A;  2L80 A;  2LRI C;  5H1U A;  2E6S A;  2C2L A;  4YAD A;  4W4U A;  4GNG A;  2VP7 A;  4IC3 A;  4LJN A;  4ZUX U;  4FK5 A;  5B79 A;  4FJC A;  4N3W A;  2CT2 A;  5TDR A;  5B76 A;  5H9M A;  3T6R A;  1RMD A;  1LDK C;  2L75 A;  3N9O A;  1VD4 A;  2MNY A;  4C9Z A;  4N4F A;  2M85 A;  3SOU A;  5B75 A;  2VJE B;  3MHH A;  2LN0 A;  2NAA A;  2KFT A;  3DQV R;  2KIZ A;  1WIM A;  3QZV A;  2E6R A;  1MM2 A;  2XB1 A;  2H0D A;  4I7D A;  5D1K B;  4GND A;  4MVT A;  5EYA F;  3GV4 A;  4AYC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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