3KDEC

Crystal structure of the thap domain from d. melanogaster p-element transposase in complex with its natural dna binding site
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
76
structure length
74
Chain Sequence
MKYCKFCCKAVTGVKLIHVPKCAIKRKLWEQSLGCSLGENSQICDTHFNDSQWKAAKGQTFKRRRLNADAVPSK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves.
pubmed doi rcsb
molecule tags Dna binding protein/dna
source organism Drosophila melanogaster
molecule keywords 5'-D(*GP*TP*TP*AP*AP*GP*(BRU)P*GP*GP*A)-3'
total genus 13
structure length 74
sequence length 76
ec nomenclature
pdb deposition date 2009-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF05485 THAP THAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.180 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Herpes Virus-1 3kdeC01
2LAUA 2JM3A 3KDEC
chains in the Genus database with same CATH superfamily
4C9ZA 1HYJA 2OWAA 1WEWA 2FD4A 4Q6FA 3N9MA 2KKYA 3ZPV1 4IC2A 2MA6A 3FM8C 2LV9A 4V3KC 2VJEA 2L43A 2MD8C 2YHOA 3RPGB 2DSMA 4GB0A 2KREA 2FSAA 5LKXA 4ZQLA 3HCSA 2JRJA 5SVYA 3RTRB 5LKTA 2DX8A 4LJNA 3ZVZB 2LXHC 4YADA 3NG2A 2MNZA 2YW8A 2G43A 1WEQA 1WFKA 4GNDA 4FJCA 4WZ3B 2LGLA 3N9LA 4QQ4A 2JMJA 4LK9A 2XB1A 3M63A 5G05B 5H1TA 5FB0A 4R7EA 4L58A 5SVIB 3LDYA 4CCGX 2CKLA 4UP0A 3M7KA 3N9PA 2VP7A 1Z60A 2F42A 2PNXA 1E4UA 3DPLR 4ZDTA 1X4UA 2KFTA 2MT5A 3ZNIA 2LN0A 2EA6A 2YSMA 5TRBA 2Y1MA 2ECGA 3GV4A 1WESA 1X4IA 1VYXA 3KDEC 1WEMA 3LVQE 1WEEA 3O36A 3O47A 1IYMA 2KGGA 2YQMA 5TDWA 2M6MA 2AN6A 5B77A 2LAUA 4YBSA 5G0FA 5LCWB 2EXUA 3T6RA 4F52B 2LGVA 2MIQA 4AP4A 2CONA 3DQVR 3ASLA 3SUBA 4O64A 3FJUB 5C13A 3LQJA 2LGGA 3MHSA 3HCUA 5KH7A 1DVPA 2MA5A 2RR4A 2Y1NA 2FUIA 2M13A 5J3XA 5LKUA 2KWOA 4PPEA 5DKAA 2ECTA 2MUMA 2JM3A 3LJUX 1F62A 4XI1A 2G6QA 3HTKC 4FIPA 3O7AA 3QZVA 2RSDA 4YAXA 5I3LA 3N9QA 2K4DA 4OGEA 3ZTGA 1FP0A 1WEUA 3O37A 1ZBDB 4BBQA 5B8DA 5H9MA 2QIZA 5SVXA 4O62A 2M1RA 1LDJB 2L0BA 4GNFA 1RMDA 3LRQA 5B75A 4AYCA 2K17A 2YVRA 2KWNA 2VJEB 3I2DA 1JM7A 2VPEA 3T9KA 1JM7B 3O35A 1T1HA 2YT5A 2LDRA 4N3WA 1DCQA 5JG6A 2ZETC 3SOUA 3ZYQA 2E6RA 4W4UA 4QF2A 2KU3A 1WE9A 1WEOA 2VJFA 3H7HA 4GNEA 2ECJA 4A4CA 2FUUA 4MVTA 4B7YC 3GL6A 1WILA 5AIUA 5DINA 3EB5A 2Y43A 4UP5A 3DWDA 3SOXA 2CKLB 2KKXA 3KV5A 4NN2A 4WA6A 4MSXA 2HDPA 2CRRA 3C5KA 3T7LA 3M99A 4CA1A 2YREA 2PUYA 2VPBA 1Z6UA 3JUEA 5FERA 3U5MA 4R2YA 2M3HA 1WGMA 5K3QA 2P57A 4I7CA 5KH9A 4A4BA 3N9NA 2EODA 3M62A 5TDRA 1HYIA 3PUQA 1MBMA 3HCTA 1X4JA 1V87A 3DDTA 2H0DA 4A49A 3PHDA 1Z2QA 2B0OE 2FFWA 4LKAA 1G25A 2M85A 2YYRA 2UZGA 2G45A 4X3GA 3ZPVE 2MKEA 1XWHA 3FAOA 3SHBA 3IHPA 2L7PA 1K2FA 1LDKC 2LQ6A 4QF3A 5B78A 2E6SA 3LQIA 2F6NA 4S3OC 2KR4A 2XEUA 1WENA 4YC9A 1VFYA 2L80A 2MNYA 4P5OB 3MDBC 4YBMA 2CRWA 2C2VS 4Z0RA 5TABA 3N9OA 4YBTA 1CHCA 5LKZA 2XP0A 4FO9A 4WZ0A 2KIZA 4AYCB 2YUCA 2IDAA 3FEHA 2KE1A 2LGKA 4H9DA 5D1MB 4BHWA 2BAYA 2DJAA 4YABA 2K1JA 5D1KB 5FEYA 2JMDA 2ECVA 3L11A 2D8UA 1WEPA 1MM2A 2QJ0A 3U5OA 2KWJA 4IC3A 2CSZA 2I50A 2MD7B 5H1UA 3U5PA 2KGIA 3RPGC 3KV6A 5G04B 2ECWA 4WZ2A 3O70A 2VJFB 2YSJA 5EYAF 2L5UA 2ECNA 2LXPC 2XOCA 2CT2A 4L7XA 1N87A 4I7BA 1WEVA 1JOCA 3U5NA 2YU4A 2XOYA 2VPGA 3L1XA 5H1VA 4AVXA 2QICA 2L75A 5B79A 3O33A 3KNVA 3LVRE 4B86C 2HYED 2YHNA 5SVIA 2OXQC 4LADB 5FB1A 1FBVA 5C11A 4LLBA 4A0CD 5D1LB 4V3LC 2EGMA 5B76A 1MM3A 4PTBA 2VNFA 2K16A 2KYUA 4OGCA 3SOWA 2H0DB 3O34A 2ECIA 3E2DA 3VK6A 2CSYA 4UI9B 3EB6A 4FK5A 2CSVA 2F6JA 3MHHA 2IQJA 4YATA 5KH3A 1BORA 2JUNA 4N4FA 2NAAA 3PLWA 3Q1DA 4I7DA 1VD4A 4S3OB 3ZVYA 2D8SA 4TKPB 2RI7A 4Z0OA 5TBNA 1U6GB 2JMIA 4GNGA 2C2LA 3LQHA 2XOZA 4ZUXU 4F1PA 2YURA 2LRIC 3KQIA 3C6WA 3V43A 4R8PK 3FANA 1WIMA 3PURA 2KWKA 2E61A 4AUQB 5AITA 2YQLA 3L1ZB 2VPDA 2EGPA 3FL2A
chains in the Genus database with same CATH topology
5SVIA 4Z0OA 5K3QA 2M13A 2P57A 5SVYA 2FFWA 2OWAA 5SVIB 3LDYA 3MDBC 2CRWA 2XOCA 5SVXA 2FD4A 3M7KA 2CSVA 1DCQA 2D8UA 2LAUA 2KKYA 3DWDA 4O62A 2KKXA 2EXUA 2XOZA 4Z0RA 2JM3A 3LJUX 2EGMA 2XOYA 2CRRA 2MKEA 2XP0A 3FM8C 4F1PA 2CONA 2IQJA 3SUBA 2L7PA 3FJUB 4QQ4A 2JUNA 4OGCA 3DDTA 2YREA 2YVRA 3PLWA 3Q1DA 3H7HA 3FEHA 3KDEC 4H9DA 3T9KA 2E61A 2DJAA 3JUEA 3E2DA 3LVQE 3LVRE 2RR4A 4OGEA 3O47A 2B0OE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LAU A;  2JM3 A;  3KDE C; 
#chains in the Genus database with same CATH topology
 4C9Z A;  1HYJ A;  2OWA A;  1WEW A;  2FD4 A;  4Q6F A;  3N9M A;  2KKY A;  3ZPV 1;  4IC2 A;  2MA6 A;  3FM8 C;  2LV9 A;  4V3K C;  2VJE A;  2L43 A;  2MD8 C;  2YHO A;  3RPG B;  2DSM A;  4GB0 A;  2KRE A;  2FSA A;  5LKX A;  4ZQL A;  3HCS A;  2JRJ A;  5SVY A;  3RTR B;  5LKT A;  2DX8 A;  4LJN A;  3ZVZ B;  2LXH C;  4YAD A;  3NG2 A;  2MNZ A;  2YW8 A;  2G43 A;  1WEQ A;  1WFK A;  4GND A;  4FJC A;  4WZ3 B;  2LGL A;  3N9L A;  4QQ4 A;  2JMJ A;  4LK9 A;  2XB1 A;  3M63 A;  5G05 B;  5H1T A;  5FB0 A;  4R7E A;  4L58 A;  5SVI B;  3LDY A;  4CCG X;  2CKL A;  4UP0 A;  3M7K A;  3N9P A;  2VP7 A;  1Z60 A;  2F42 A;  2PNX A;  1E4U A;  3DPL R;  4ZDT A;  1X4U A;  2KFT A;  2MT5 A;  3ZNI A;  2LN0 A;  2EA6 A;  2YSM A;  5TRB A;  2Y1M A;  2ECG A;  3GV4 A;  1WES A;  1X4I A;  1VYX A;  3KDE C;  1WEM A;  3LVQ E;  1WEE A;  3O36 A;  3O47 A;  1IYM A;  2KGG A;  2YQM A;  5TDW A;  2M6M A;  2AN6 A;  5B77 A;  2LAU A;  4YBS A;  5G0F A;  5LCW B;  2EXU A;  3T6R A;  4F52 B;  2LGV A;  2MIQ A;  4AP4 A;  2CON A;  3DQV R;  3ASL A;  3SUB A;  4O64 A;  3FJU B;  5C13 A;  3LQJ A;  2LGG A;  3MHS A;  3HCU A;  5KH7 A;  1DVP A;  2MA5 A;  2RR4 A;  2Y1N A;  2FUI A;  2M13 A;  5J3X A;  5LKU A;  2KWO A;  4PPE A;  5DKA A;  2ECT A;  2MUM A;  2JM3 A;  3LJU X;  1F62 A;  4XI1 A;  2G6Q A;  3HTK C;  4FIP A;  3O7A A;  3QZV A;  2RSD A;  4YAX A;  5I3L A;  3N9Q A;  2K4D A;  4OGE A;  3ZTG A;  1FP0 A;  1WEU A;  3O37 A;  1ZBD B;  4BBQ A;  5B8D A;  5H9M A;  2QIZ A;  5SVX A;  4O62 A;  2M1R A;  1LDJ B;  2L0B A;  4GNF A;  1RMD A;  3LRQ A;  5B75 A;  4AYC A;  2K17 A;  2YVR A;  2KWN A;  2VJE B;  3I2D A;  1JM7 A;  2VPE A;  3T9K A;  1JM7 B;  3O35 A;  1T1H A;  2YT5 A;  2LDR A;  4N3W A;  1DCQ A;  5JG6 A;  2ZET C;  3SOU A;  3ZYQ A;  2E6R A;  4W4U A;  4QF2 A;  2KU3 A;  1WE9 A;  1WEO A;  2VJF A;  3H7H A;  4GNE A;  2ECJ A;  4A4C A;  2FUU A;  4MVT A;  4B7Y C;  3GL6 A;  1WIL A;  5AIU A;  5DIN A;  3EB5 A;  2Y43 A;  4UP5 A;  3DWD A;  3SOX A;  2CKL B;  2KKX A;  3KV5 A;  4NN2 A;  4WA6 A;  4MSX A;  2HDP A;  2CRR A;  3C5K A;  3T7L A;  3M99 A;  4CA1 A;  2YRE A;  2PUY A;  2VPB A;  1Z6U A;  3JUE A;  5FER A;  3U5M A;  4R2Y A;  2M3H A;  1WGM A;  5K3Q A;  2P57 A;  4I7C A;  5KH9 A;  4A4B A;  3N9N A;  2EOD A;  3M62 A;  5TDR A;  1HYI A;  3PUQ A;  1MBM A;  3HCT A;  1X4J A;  1V87 A;  3DDT A;  2H0D A;  4A49 A;  3PHD A;  1Z2Q A;  2B0O E;  2FFW A;  4LKA A;  1G25 A;  2M85 A;  2YYR A;  2UZG A;  2G45 A;  4X3G A;  3ZPV E;  2MKE A;  1XWH A;  3FAO A;  3SHB A;  3IHP A;  2L7P A;  1K2F A;  1LDK C;  2LQ6 A;  4QF3 A;  5B78 A;  2E6S A;  3LQI A;  2F6N A;  4S3O C;  2KR4 A;  2XEU A;  1WEN A;  4YC9 A;  1VFY A;  2L80 A;  2MNY A;  4P5O B;  3MDB C;  4YBM A;  2CRW A;  2C2V S;  4Z0R A;  5TAB A;  3N9O A;  4YBT A;  1CHC A;  5LKZ A;  2XP0 A;  4FO9 A;  4WZ0 A;  2KIZ A;  4AYC B;  2YUC A;  2IDA A;  3FEH A;  2KE1 A;  2LGK A;  4H9D A;  5D1M B;  4BHW A;  2BAY A;  2DJA A;  4YAB A;  2K1J A;  5D1K B;  5FEY A;  2JMD A;  2ECV A;  3L11 A;  2D8U A;  1WEP A;  1MM2 A;  2QJ0 A;  3U5O A;  2KWJ A;  4IC3 A;  2CSZ A;  2I50 A;  2MD7 B;  5H1U A;  3U5P A;  2KGI A;  3RPG C;  3KV6 A;  5G04 B;  2ECW A;  4WZ2 A;  3O70 A;  2VJF B;  2YSJ A;  5EYA F;  2L5U A;  2ECN A;  2LXP C;  2XOC A;  2CT2 A;  4L7X A;  1N87 A;  4I7B A;  1WEV A;  1JOC A;  3U5N A;  2YU4 A;  2XOY A;  2VPG A;  3L1X A;  5H1V A;  4AVX A;  2QIC A;  2L75 A;  5B79 A;  3O33 A;  3KNV A;  3LVR E;  4B86 C;  2HYE D;  2YHN A;  5SVI A;  2OXQ C;  4LAD B;  5FB1 A;  1FBV A;  5C11 A;  4LLB A;  4A0C D;  5D1L B;  4V3L C;  2EGM A;  5B76 A;  1MM3 A;  4PTB A;  2VNF A;  2K16 A;  2KYU A;  4OGC A;  3SOW A;  2H0D B;  3O34 A;  2ECI A;  3E2D A;  3VK6 A;  2CSY A;  4UI9 B;  3EB6 A;  4FK5 A;  2CSV A;  2F6J A;  3MHH A;  2IQJ A;  4YAT A;  5KH3 A;  1BOR A;  2JUN A;  4N4F A;  2NAA A;  3PLW A;  3Q1D A;  4I7D A;  1VD4 A;  4S3O B;  3ZVY A;  2D8S A;  4TKP B;  2RI7 A;  4Z0O A;  5TBN A;  1U6G B;  2JMI A;  4GNG A;  2C2L A;  3LQH A;  2XOZ A;  4ZUX U;  4F1P A;  2YUR A;  2LRI C;  3KQI A;  3C6W A;  3V43 A;  4R8P K;  3FAN A;  1WIM A;  3PUR A;  2KWK A;  2E61 A;  4AUQ B;  5AIT A;  2YQL A;  3L1Z B;  2VPD A;  2EGP A;  3FL2 A; 
#chains in the Genus database with same CATH homology
 5SVI A;  4Z0O A;  5K3Q A;  2M13 A;  2P57 A;  5SVY A;  2FFW A;  2OWA A;  5SVI B;  3LDY A;  3MDB C;  2CRW A;  2XOC A;  5SVX A;  2FD4 A;  3M7K A;  2CSV A;  1DCQ A;  2D8U A;  2LAU A;  2KKY A;  3DWD A;  4O62 A;  2KKX A;  2EXU A;  2XOZ A;  4Z0R A;  2JM3 A;  3LJU X;  2EGM A;  2XOY A;  2CRR A;  2MKE A;  2XP0 A;  3FM8 C;  4F1P A;  2CON A;  2IQJ A;  3SUB A;  2L7P A;  3FJU B;  4QQ4 A;  2JUN A;  4OGC A;  3DDT A;  2YRE A;  2YVR A;  3PLW A;  3Q1D A;  3H7H A;  3FEH A;  3KDE C;  4H9D A;  3T9K A;  2E61 A;  2DJA A;  3JUE A;  3E2D A;  3LVQ E;  3LVR E;  2RR4 A;  4OGE A;  3O47 A;  2B0O E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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