4Z0RA

Crystal structure of the cw domain of zcwpw2 mutant f78r in complex with histone h3 peptide
Total Genus 10
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
57
structure length
57
Chain Sequence
ENMYVNKVWVQCENENCLKWRLLSSEDSAKVDHDEPWYCFMNTDSRYNNCSISEEDR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure of the CW domain of ZCWPW2 mutant F78R in complex with histone H3 peptide
rcsb
molecule tags Protein binding/structural protein
source organism Homo sapiens
molecule keywords Zinc finger CW-type PWWP domain protein 2
total genus 10
structure length 57
sequence length 57
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2015-03-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07496 zf-CW CW-type Zinc Finger
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.100 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Herpes Virus-1 4z0rA00
4QQ4A 5SVYA 2E61A 4Z0OA 4O62A 5SVXA 5SVIA 2RR4A 2L7PA 5SVIB 4Z0RA
chains in the Genus database with same CATH superfamily
2EXUA 4MSXA 2KU3A 1F62A 2YQLA 3O47A 3N9QA 3T9KA 4AVXA 3MDBC 5EYAF 4Z0OA 4ZQLA 3GL6A 2L5UA 2JUNA 4GNEA 1RMDA 4L7XA 1CHCA 3ZNIA 3O37A 2LQ6A 5KH9A 4LJNA 2KKYA 3FAOA 4YATA 5D1KB 2KGGA 2YREA 2ECVA 5G04B 2KYUA 4O64A 2L7PA 1WIMA 3M99A 4W4UA 2YHNA 3SUBA 1WE9A 3ZVZB 4LADB 2VP7A 2M13A 4GNDA 4O62A 2YSJA 2VPEA 2IQJA 2LGKA 2KR4A 1WENA 2KWJA 1N87A 2H0DB 4V3KC 3ASLA 2XP0A 4MVTA 4TKPB 4IC3A 3FANA 4X3GA 2NAAA 4I7BA 1E4UA 1JM7A 4A0CD 2H0DA 4BHWA 2L80A 4F52B 2L75A 2M6MA 5LKZA 5SVIA 2FFWA 4V3LC 3FM8C 5SVXA 5H9MA 4C9ZA 5I3LA 2HDPA 1U6GB 2MUMA 4L58A 2PUYA 5JG6A 4Z0RA 2LXPC 2MNZA 2MT5A 3LVQE 3KNVA 3DQVR 4YAXA 2K17A 3ZVYA 2ZETC 3VK6A 2LV9A 2IDAA 2VJFB 2KIZA 3O7AA 2CSVA 2LAUA 2LGGA 2DJAA 5LCWB 5C11A 1VFYA 4LLBA 2G45A 2XOCA 2VPBA 4OGCA 5B75A 4WZ3B 3FEHA 3U5OA 2MA6A 1X4JA 2VJEA 2B0OE 1X4UA 2OWAA 3N9NA 2JMDA 1WEEA 4H9DA 2E6RA 3PLWA 3O36A 4AP4A 4YADA 2YSMA 2CT2A 2F42A 3FL2A 4ZUXU 4WZ2A 2C2LA 5G0FA 2KE1A 3DDTA 1WFKA 2K4DA 2JMJA 3T6RA 2D8UA 3O34A 1K2FA 2VPDA 3E2DA 3QZVA 3ZYQA 4B7YC 3U5NA 2PNXA 2CRRA 4A4BA 3O70A 5TBNA 2RR4A 2EGPA 2QICA 2ECGA 4A4CA 2EODA 4PTBA 2F6NA 2KWOA 2G43A 3DPLR 3N9MA 1FP0A 3KV5A 3LDYA 3LQHA 3PHDA 4YC9A 3M63A 3FJUB 3SHBA 2YYRA 5LKUA 4GNFA 2LXHC 2E6SA 1Z6UA 2FUUA 2CKLB 5TABA 4UP0A 5G05B 2EA6A 4GNGA 1HYJA 4AYCB 1T1HA 4AUQB 3SOXA 1WEQA 5LKXA 4UP5A 1FBVA 2OXQC 2JMIA 2YVRA 5TDWA 1VYXA 2BAYA 2EGMA 3GV4A 2MD8C 5D1LB 4N4FA 2ECWA 3ZPVE 5H1TA 3SOUA 2KGIA 3PURA 2LRIC 2JRJA 4I7CA 5B76A 2P57A 4R7EA 5FEYA 3T7LA 2VNFA 1IYMA 2E61A 1Z2QA 2FD4A 4BBQA 2JM3A 2K16A 3SOWA 4QF3A 4F1PA 3N9LA 2ECIA 4GB0A 3N9OA 2M1RA 1WILA 2CRWA 3EB5A 5B77A 2CSYA 2AN6A 2QIZA 5SVYA 4N3WA 3KDEC 2YHOA 5FB1A 1LDKC 1X4IA 5K3QA 4FJCA 2LGVA 2VJFA 1HYIA 2ECNA 3L11A 1WEOA 2KREA 3MHHA 1MM2A 1VD4A 4B86C 3HCTA 2M85A 2FUIA 2Y1NA 3O33A 2K1JA 3RPGC 4YBSA 1BORA 2FSAA 2YU4A 3JUEA 1Z60A 2Y1MA 1LDJB 3LQJA 4UI9B 5DINA 1JOCA 5B8DA 3M7KA 4R8PK 5D1MB 4S3OB 2MA5A 2MKEA 3LRQA 3L1XA 4ZDTA 2XB1A 3U5PA 1DCQA 3U5MA 5H1UA 3O35A 5FB0A 4XI1A 4WA6A 3ZPV1 1V87A 3L1ZB 5J3XA 5AIUA 1XWHA 2YW8A 4YABA 2DSMA 4YBMA 3NG2A 3RPGB 2ECJA 3MHSA 5TRBA 1WESA 2XOZA 3C6WA 1ZBDB 4FK5A 3N9PA 2M3HA 3C5KA 3EB6A 3LJUX 2MNYA 2MIQA 2YT5A 1DVPA 1WEVA 3LQIA 5KH3A 1WEWA 2G6QA 5LKTA 1JM7B 1MM3A 2CKLA 2ECTA 4CA1A 2I50A 4LK9A 3I2DA 3HTKC 1WEMA 4AYCA 2LN0A 2LGLA 5SVIB 2F6JA 4CCGX 4NN2A 2VPGA 2KKXA 4P5OB 5FERA 3H7HA 2YUCA 4YBTA 2Y43A 4FO9A 2C2VS 3LVRE 4WZ0A 3M62A 2HYED 3KQIA 2YQMA 2L43A 1MBMA 2QJ0A 3Q1DA 3HCUA 1WGMA 1WEPA 1G25A 2UZGA 2LDRA 4S3OC 1WEUA 3V43A 5DKAA 2MD7B 3PUQA 5TDRA 2XOYA 2VJEB 4QQ4A 3ZTGA 2L0BA 2XEUA 3HCSA 3KV6A 4QF2A 2YURA 2KWNA 4R2YA 4Q6FA 5AITA 2DX8A 5B79A 2RI7A 3RTRB 3IHPA 2KWKA 4A49A 4OGEA 3DWDA 4IC2A 5KH7A 4PPEA 5H1VA 2CSZA 2D8SA 2CONA 2RSDA 5C13A 4LKAA 4I7DA 2KFTA 5B78A 4FIPA
chains in the Genus database with same CATH topology
2XOZA 2EXUA 2XOCA 2YREA 1DCQA 2CRWA 3O47A 4OGCA 2KKXA 3T9KA 2L7PA 3MDBC 4Z0OA 2P57A 4Z0RA 5SVYA 3LVQE 3LJUX 3KDEC 3DDTA 3H7HA 3FEHA 3SUBA 3JUEA 2D8UA 5K3QA 3E2DA 2JUNA 4OGEA 2YVRA 3DWDA 2E61A 2B0OE 2FD4A 2M13A 2CRRA 4O62A 2OWAA 3LDYA 2EGMA 2JM3A 2IQJA 2RR4A 3LVRE 3M7KA 4H9DA 3FJUB 5SVIA 2FFWA 2CONA 2XOYA 3FM8C 4F1PA 4QQ4A 2KKYA 2MKEA 5SVXA 3PLWA 2CSVA 2LAUA 2XP0A 2DJAA 5SVIB 3Q1DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QQ4 A;  5SVY A;  2E61 A;  4Z0O A;  4O62 A;  5SVX A;  5SVI A;  2RR4 A;  2L7P A;  5SVI B;  4Z0R A; 
#chains in the Genus database with same CATH topology
 2EXU A;  4MSX A;  2KU3 A;  1F62 A;  2YQL A;  3O47 A;  3N9Q A;  3T9K A;  4AVX A;  3MDB C;  5EYA F;  4Z0O A;  4ZQL A;  3GL6 A;  2L5U A;  2JUN A;  4GNE A;  1RMD A;  4L7X A;  1CHC A;  3ZNI A;  3O37 A;  2LQ6 A;  5KH9 A;  4LJN A;  2KKY A;  3FAO A;  4YAT A;  5D1K B;  2KGG A;  2YRE A;  2ECV A;  5G04 B;  2KYU A;  4O64 A;  2L7P A;  1WIM A;  3M99 A;  4W4U A;  2YHN A;  3SUB A;  1WE9 A;  3ZVZ B;  4LAD B;  2VP7 A;  2M13 A;  4GND A;  4O62 A;  2YSJ A;  2VPE A;  2IQJ A;  2LGK A;  2KR4 A;  1WEN A;  2KWJ A;  1N87 A;  2H0D B;  4V3K C;  3ASL A;  2XP0 A;  4MVT A;  4TKP B;  4IC3 A;  3FAN A;  4X3G A;  2NAA A;  4I7B A;  1E4U A;  1JM7 A;  4A0C D;  2H0D A;  4BHW A;  2L80 A;  4F52 B;  2L75 A;  2M6M A;  5LKZ A;  5SVI A;  2FFW A;  4V3L C;  3FM8 C;  5SVX A;  5H9M A;  4C9Z A;  5I3L A;  2HDP A;  1U6G B;  2MUM A;  4L58 A;  2PUY A;  5JG6 A;  4Z0R A;  2LXP C;  2MNZ A;  2MT5 A;  3LVQ E;  3KNV A;  3DQV R;  4YAX A;  2K17 A;  3ZVY A;  2ZET C;  3VK6 A;  2LV9 A;  2IDA A;  2VJF B;  2KIZ A;  3O7A A;  2CSV A;  2LAU A;  2LGG A;  2DJA A;  5LCW B;  5C11 A;  1VFY A;  4LLB A;  2G45 A;  2XOC A;  2VPB A;  4OGC A;  5B75 A;  4WZ3 B;  3FEH A;  3U5O A;  2MA6 A;  1X4J A;  2VJE A;  2B0O E;  1X4U A;  2OWA A;  3N9N A;  2JMD A;  1WEE A;  4H9D A;  2E6R A;  3PLW A;  3O36 A;  4AP4 A;  4YAD A;  2YSM A;  2CT2 A;  2F42 A;  3FL2 A;  4ZUX U;  4WZ2 A;  2C2L A;  5G0F A;  2KE1 A;  3DDT A;  1WFK A;  2K4D A;  2JMJ A;  3T6R A;  2D8U A;  3O34 A;  1K2F A;  2VPD A;  3E2D A;  3QZV A;  3ZYQ A;  4B7Y C;  3U5N A;  2PNX A;  2CRR A;  4A4B A;  3O70 A;  5TBN A;  2RR4 A;  2EGP A;  2QIC A;  2ECG A;  4A4C A;  2EOD A;  4PTB A;  2F6N A;  2KWO A;  2G43 A;  3DPL R;  3N9M A;  1FP0 A;  3KV5 A;  3LDY A;  3LQH A;  3PHD A;  4YC9 A;  3M63 A;  3FJU B;  3SHB A;  2YYR A;  5LKU A;  4GNF A;  2LXH C;  2E6S A;  1Z6U A;  2FUU A;  2CKL B;  5TAB A;  4UP0 A;  5G05 B;  2EA6 A;  4GNG A;  1HYJ A;  4AYC B;  1T1H A;  4AUQ B;  3SOX A;  1WEQ A;  5LKX A;  4UP5 A;  1FBV A;  2OXQ C;  2JMI A;  2YVR A;  5TDW A;  1VYX A;  2BAY A;  2EGM A;  3GV4 A;  2MD8 C;  5D1L B;  4N4F A;  2ECW A;  3ZPV E;  5H1T A;  3SOU A;  2KGI A;  3PUR A;  2LRI C;  2JRJ A;  4I7C A;  5B76 A;  2P57 A;  4R7E A;  5FEY A;  3T7L A;  2VNF A;  1IYM A;  2E61 A;  1Z2Q A;  2FD4 A;  4BBQ A;  2JM3 A;  2K16 A;  3SOW A;  4QF3 A;  4F1P A;  3N9L A;  2ECI A;  4GB0 A;  3N9O A;  2M1R A;  1WIL A;  2CRW A;  3EB5 A;  5B77 A;  2CSY A;  2AN6 A;  2QIZ A;  5SVY A;  4N3W A;  3KDE C;  2YHO A;  5FB1 A;  1LDK C;  1X4I A;  5K3Q A;  4FJC A;  2LGV A;  2VJF A;  1HYI A;  2ECN A;  3L11 A;  1WEO A;  2KRE A;  3MHH A;  1MM2 A;  1VD4 A;  4B86 C;  3HCT A;  2M85 A;  2FUI A;  2Y1N A;  3O33 A;  2K1J A;  3RPG C;  4YBS A;  1BOR A;  2FSA A;  2YU4 A;  3JUE A;  1Z60 A;  2Y1M A;  1LDJ B;  3LQJ A;  4UI9 B;  5DIN A;  1JOC A;  5B8D A;  3M7K A;  4R8P K;  5D1M B;  4S3O B;  2MA5 A;  2MKE A;  3LRQ A;  3L1X A;  4ZDT A;  2XB1 A;  3U5P A;  1DCQ A;  3U5M A;  5H1U A;  3O35 A;  5FB0 A;  4XI1 A;  4WA6 A;  3ZPV 1;  1V87 A;  3L1Z B;  5J3X A;  5AIU A;  1XWH A;  2YW8 A;  4YAB A;  2DSM A;  4YBM A;  3NG2 A;  3RPG B;  2ECJ A;  3MHS A;  5TRB A;  1WES A;  2XOZ A;  3C6W A;  1ZBD B;  4FK5 A;  3N9P A;  2M3H A;  3C5K A;  3EB6 A;  3LJU X;  2MNY A;  2MIQ A;  2YT5 A;  1DVP A;  1WEV A;  3LQI A;  5KH3 A;  1WEW A;  2G6Q A;  5LKT A;  1JM7 B;  1MM3 A;  2CKL A;  2ECT A;  4CA1 A;  2I50 A;  4LK9 A;  3I2D A;  3HTK C;  1WEM A;  4AYC A;  2LN0 A;  2LGL A;  5SVI B;  2F6J A;  4CCG X;  4NN2 A;  2VPG A;  2KKX A;  4P5O B;  5FER A;  3H7H A;  2YUC A;  4YBT A;  2Y43 A;  4FO9 A;  2C2V S;  3LVR E;  4WZ0 A;  3M62 A;  2HYE D;  3KQI A;  2YQM A;  2L43 A;  1MBM A;  2QJ0 A;  3Q1D A;  3HCU A;  1WGM A;  1WEP A;  1G25 A;  2UZG A;  2LDR A;  4S3O C;  1WEU A;  3V43 A;  5DKA A;  2MD7 B;  3PUQ A;  5TDR A;  2XOY A;  2VJE B;  4QQ4 A;  3ZTG A;  2L0B A;  2XEU A;  3HCS A;  3KV6 A;  4QF2 A;  2YUR A;  2KWN A;  4R2Y A;  4Q6F A;  5AIT A;  2DX8 A;  5B79 A;  2RI7 A;  3RTR B;  3IHP A;  2KWK A;  4A49 A;  4OGE A;  3DWD A;  4IC2 A;  5KH7 A;  4PPE A;  5H1V A;  2CSZ A;  2D8S A;  2CON A;  2RSD A;  5C13 A;  4LKA A;  4I7D A;  2KFT A;  5B78 A;  4FIP A; 
#chains in the Genus database with same CATH homology
 2XOZ A;  2EXU A;  2XOC A;  2YRE A;  1DCQ A;  2CRW A;  3O47 A;  4OGC A;  2KKX A;  3T9K A;  2L7P A;  3MDB C;  4Z0O A;  2P57 A;  4Z0R A;  5SVY A;  3LVQ E;  3LJU X;  3KDE C;  3DDT A;  3H7H A;  3FEH A;  3SUB A;  3JUE A;  2D8U A;  5K3Q A;  3E2D A;  2JUN A;  4OGE A;  2YVR A;  3DWD A;  2E61 A;  2B0O E;  2FD4 A;  2M13 A;  2CRR A;  4O62 A;  2OWA A;  3LDY A;  2EGM A;  2JM3 A;  2IQJ A;  2RR4 A;  3LVR E;  3M7K A;  4H9D A;  3FJU B;  5SVI A;  2FFW A;  2CON A;  2XOY A;  3FM8 C;  4F1P A;  4QQ4 A;  2KKY A;  2MKE A;  5SVX A;  3PLW A;  2CSV A;  2LAU A;  2XP0 A;  2DJA A;  5SVI B;  3Q1D A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...