4GNGA

Crystal structure of nsd3 tandem phd5-c5hch domains complexed with h3k9me3 peptide
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
95
structure length
95
Chain Sequence
MHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPYGKWECPWHQCDECSSAAVSFCEFCPHSFCKDHEKGALVPSALEGRLCCSEHDPMAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
pubmed doi rcsb
molecule tags Transferase/nuclear protein
source organism Homo sapiens
molecule keywords Histone-lysine N-methyltransferase NSD3
total genus 18
structure length 95
sequence length 95
chains with identical sequence D
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2012-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF17982 C5HCH NSD Cys-His rich domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.10 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Zinc/RING finger domain, C3HC4 (zinc finger) 4gngA00
2ECIA 1K2FA 1FP0A 5TDWA 3C6WA 2YYRA 2LN0A 3ASLA 2XEUA 3HCUA 4CCGX 1Z6UA 3HCTA 4LLBA 4GNDA 1WEMA 2EA6A 4BBQA 5B77A 4C9ZA 2CSZA 2MT5A 2HYED 3HTKC 3N9LA 4I7BA 3RPGC 2MNYA 4UP5A 2K1JA 2ECTA 1E4UA 3O70A 4AP4A 2ECNA 5FB1A 1LDJB 4FIPA 2LXPC 2QJ0A 5LKZA 2YSMA 5B75A 2Y43A 2M6MA 4FJCA 2IDAA 2FUUA 3I2DA 2LV9A 2G43A 4YADA 5EYAF 3M63A 2YURA 4R7EA 2YT5A 4L7XA 4Q6FA 5B76A 3O35A 4X3GA 5AITA 2LGLA 2VJEB 3MHSA 3O34A 5JG6A 1X4JA 4P5OB 3U5OA 2PUYA 5I3LA 3SOWA 3ZYQA 1WEOA 2I50A 2LQ6A 2G45A 2YUCA 5H1VA 4F52B 4YC9A 1N87A 5G05B 5G0FA 2EGPA 2F6JA 3N9PA 5D1MB 4XI1A 2RSDA 2K4DA 5TRBA 4YATA 4S3OB 2ECVA 3O36A 2JMDA 4AYCB 2KFTA 4IC3A 1VYXA 5B78A 3L11A 2VJFB 3KQIA 2MD8C 2MIQA 3MHHA 5TBNA 2XB1A 3DQVR 2L43A 5H1UA 3LQHA 3KV5A 2YHOA 4YBTA 2YQMA 3LQIA 2YW8A 3O37A 1WILA 2VJEA 4AUQB 5KH9A 1U6GB 2LRIC 4I7DA 2Y1MA 5FERA 4MSXA 5DKAA 5J3XA 1DVPA 4R2YA 3C5KA 1HYJA 3ZPV1 3VK6A 5TDRA 3N9NA 5LKTA 1MM2A 4A0CD 3L1ZB 4YBMA 5H1TA 2CT2A 4AYCA 2KGGA 4WZ3B 3SOXA 2VJFA 4WZ2A 2K16A 2LGGA 4ZUXU 4L58A 4QF3A 4UI9B 3LQJA 2VPBA 2DX8A 2H0DB 4A49A 1Z2QA 2LXHC 3IHPA 1G25A 4LKAA 2KE1A 2BAYA 3PUQA 2KWOA 2KU3A 3U5NA 3EB5A 4GNEA 4IC2A 1WEPA 3T7LA 1HYIA 1JOCA 2F42A 1JM7B 1WEQA 1WESA 4A4CA 2L80A 4WA6A 4WZ0A 1BORA 2NAAA 1F62A 4GNFA 2MA5A 1VD4A 2JMIA 2K17A 4YBSA 2UZGA 1XWHA 3ZTGA 3PHDA 3QZVA 2VNFA 3HCSA 4S3OC 1WE9A 2HDPA 5LKXA 3LRQA 5DINA 4ZDTA 5AIUA 3PURA 4PPEA 2M3HA 4R8PK 4MVTA 2YSJA 4TKPB 1WIMA 2E6SA 3ZNIA 2VPEA 4YAXA 3SOUA 4B86C 1X4UA 3M62A 2ECJA 2YHNA 2KYUA 2KREA 3SHBA 2OXQC 3ZVZB 4AVXA 1ZBDB 3RTRB 3T6RA 2MA6A 5LKUA 4B7YC 2PNXA 2H0DA 2KGIA 2QICA 2QIZA 4W4UA 2G6QA 5B79A 1CHCA 1JM7A 2C2VS 4N3WA 2F6NA 4FK5A 2VP7A 2YQLA 5G04B 3O33A 2KWKA 1FBVA 3GV4A 3NG2A 2LGVA 3U5MA 2Y1NA 5B8DA 1WEVA 2L0BA 1X4IA 1WGMA 4ZQLA 2MD7B 4NN2A 5KH7A 1IYMA 4CA1A 5C13A 5TABA 4LJNA 3EB6A 3ZVYA 2C2LA 1WENA 1MM3A 2FSAA 2M1RA 3O7AA 2FUIA 2KIZA 3FL2A 3DPLR 3RPGB 4BHWA 4FO9A 3N9MA 4A4BA 4QF2A 5FB0A 3GL6A 2CKLB 4PTBA 2YU4A 2CSYA 2L5UA 3KNVA 1WEUA 3L1XA 2KWNA 2KWJA 2LGKA 1WEWA 2ECWA 4GB0A 3M99A 2ECGA 1WEEA 4YABA 2D8SA 5KH3A 1RMDA 2EODA 2E6RA 1Z60A 2VPDA 4V3LC 3N9OA 5FEYA 1T1HA 3ZPVE 2JRJA 3V43A 2RI7A 1V87A 1LDKC 5D1KB 2AN6A 4LK9A 4UP0A 2JMJA 5H9MA 5C11A 4GNGA 5LCWB 2CKLA 1WFKA 4O64A 3N9QA 4I7CA 2MNZA 4V3KC 2MUMA 2VPGA 2ZETC 4LADB 2M85A 3U5PA 3KV6A 4N4FA 2YREA 5D1LB 2L75A 2KR4A 2LDRA 1VFYA
chains in the Genus database with same CATH superfamily
2ECIA 1K2FA 1FP0A 5TDWA 3C6WA 2YYRA 2LN0A 3ASLA 2XEUA 3HCUA 4CCGX 1Z6UA 3HCTA 4LLBA 4GNDA 1WEMA 2EA6A 3MDBC 4BBQA 5B77A 4C9ZA 2XOCA 2CSZA 2MT5A 2HYED 3HTKC 3N9LA 4I7BA 3RPGC 2MNYA 4UP5A 4F1PA 2K1JA 2ECTA 1E4UA 2E61A 3O70A 4AP4A 2ECNA 5FB1A 1LDJB 4FIPA 2CONA 2LXPC 3O47A 2QJ0A 2CRWA 5LKZA 2YSMA 5B75A 3LVQE 2Y43A 2M6MA 4FJCA 2IDAA 2FUUA 3I2DA 2LV9A 2G43A 4YADA 5EYAF 3M63A 2YURA 3H7HA 5SVYA 3LJUX 4R7EA 2YT5A 4L7XA 2EGMA 4Q6FA 5B76A 3O35A 4X3GA 5AITA 2LGLA 2VJEB 3MHSA 3O34A 5JG6A 1X4JA 4P5OB 5SVIB 2YVRA 3U5OA 2PUYA 5I3LA 3SOWA 3PLWA 3ZYQA 1WEOA 2I50A 2LQ6A 3SUBA 2G45A 2YUCA 5H1VA 4F52B 4YC9A 1N87A 5G05B 5G0FA 2DSMA 2EGPA 2F6JA 3N9PA 4OGEA 5D1MB 4XI1A 2RSDA 2K4DA 5TRBA 4YATA 4S3OB 2ECVA 3O36A 2JMDA 4AYCB 2KFTA 3DDTA 1VYXA 4IC3A 5B78A 3L11A 4O62A 2VJFB 2JUNA 3KQIA 2MD8C 2MIQA 3MHHA 5TBNA 2XB1A 3DQVR 2L43A 2L7PA 5H1UA 3LQHA 3KV5A 2YHOA 4YBTA 2YQMA 3LQIA 2YW8A 3O37A 1WILA 2VJEA 4AUQB 5KH9A 1U6GB 2KKYA 5SVIA 2LRIC 4I7DA 2Y1MA 5FERA 4MSXA 5DKAA 5J3XA 1DVPA 3LVRE 4R2YA 3C5KA 1HYJA 3ZPV1 3VK6A 5TDRA 3N9NA 5LKTA 1MM2A 4A0CD 3L1ZB 4YBMA 5H1TA 2CT2A 4AYCA 2KGGA 2FD4A 4WZ3B 3SOXA 2VJFA 4WZ2A 2K16A 2LGGA 2LAUA 4ZUXU 4L58A 4QF3A 4UI9B 3LQJA 2VPBA 3JUEA 2DX8A 2H0DB 4A49A 1Z2QA 2LXHC 3IHPA 1G25A 4LKAA 2KE1A 2BAYA 3PUQA 2KWOA 3FM8C 2KU3A 3U5NA 2OWAA 3EB5A 4GNEA 4IC2A 3M7KA 1WEPA 3T7LA 1HYIA 1JOCA 2F42A 1JM7B 1WEQA 1WESA 4A4CA 2L80A 4WA6A 4WZ0A 1BORA 2NAAA 1F62A 4GNFA 2MA5A 1VD4A 2JMIA 2K17A 4YBSA 2UZGA 2DJAA 2KKXA 1XWHA 3ZTGA 2IQJA 3PHDA 3QZVA 4QQ4A 2VNFA 3HCSA 4S3OC 1WE9A 2HDPA 5LKXA 2MKEA 3LRQA 5DINA 4ZDTA 3FEHA 5AIUA 3PURA 4PPEA 2M3HA 4R8PK 3DWDA 4MVTA 2YSJA 4TKPB 1WIMA 2E6SA 3ZNIA 2VPEA 4YAXA 4Z0RA 3SOUA 4B86C 1X4UA 3M62A 2ECJA 5SVXA 2YHNA 2KYUA 2KREA 3SHBA 2OXQC 3ZVZB 4AVXA 1ZBDB 3RTRB 3T6RA 2MA6A 5LKUA 4B7YC 2PNXA 2H0DA 2KGIA 5K3QA 2QICA 2QIZA 4W4UA 2G6QA 4Z0OA 5B79A 1CHCA 1JM7A 2C2VS 4N3WA 2F6NA 3FAOA 4FK5A 2VP7A 2YQLA 5G04B 3O33A 2XOZA 2KWKA 1FBVA 2XOYA 3GV4A 3NG2A 2LGVA 3U5MA 2D8UA 2Y1NA 3Q1DA 5B8DA 1WEVA 2L0BA 1X4IA 1WGMA 2JM3A 4ZQLA 2MD7B 4OGCA 2B0OE 4NN2A 5KH7A 2M13A 1IYMA 4CA1A 2P57A 5C13A 5TABA 2FFWA 4LJNA 3EB6A 2XP0A 3ZVYA 2C2LA 1WENA 1MM3A 2FSAA 1MBMA 2M1RA 3O7AA 2FUIA 2KIZA 3FL2A 3DPLR 3RPGB 4BHWA 4FO9A 3N9MA 4A4BA 4QF2A 5FB0A 3GL6A 2CKLB 4PTBA 2YU4A 2CSYA 2L5UA 3KNVA 1WEUA 3L1XA 3FANA 2KWNA 2KWJA 3KDEC 4H9DA 2LGKA 1DCQA 1WEWA 2ECWA 4GB0A 3LDYA 3M99A 2ECGA 1WEEA 4YABA 2D8SA 5KH3A 1RMDA 2EODA 3FJUB 2E6RA 1Z60A 2VPDA 4V3LC 3N9OA 5FEYA 1T1HA 2EXUA 2CRRA 3ZPVE 2JRJA 3V43A 2RI7A 2CSVA 1V87A 1LDKC 5D1KB 2AN6A 4LK9A 4UP0A 2JMJA 5H9MA 5C11A 4GNGA 5LCWB 2CKLA 1WFKA 4O64A 3N9QA 4I7CA 2RR4A 2MNZA 4V3KC 2MUMA 2VPGA 2ZETC 4LADB 2M85A 3U5PA 3KV6A 4N4FA 2YREA 5D1LB 2L75A 3E2DA 2KR4A 2LDRA 1VFYA 3T9KA
chains in the Genus database with same CATH topology
2ECIA 1K2FA 1FP0A 5TDWA 3C6WA 2YYRA 2LN0A 3ASLA 2XEUA 3HCUA 4CCGX 1Z6UA 3HCTA 4LLBA 4GNDA 1WEMA 2EA6A 4BBQA 5B77A 4C9ZA 2CSZA 2MT5A 2HYED 3HTKC 3N9LA 4I7BA 3RPGC 2MNYA 4UP5A 2K1JA 2ECTA 1E4UA 3O70A 4AP4A 2ECNA 5FB1A 1LDJB 4FIPA 2LXPC 2QJ0A 5LKZA 2YSMA 5B75A 2Y43A 2M6MA 4FJCA 2IDAA 2FUUA 3I2DA 2LV9A 2G43A 4YADA 5EYAF 3M63A 2YURA 4R7EA 2YT5A 4L7XA 4Q6FA 5B76A 3O35A 4X3GA 5AITA 2LGLA 2VJEB 3MHSA 3O34A 5JG6A 1X4JA 4P5OB 3U5OA 2PUYA 5I3LA 3SOWA 3ZYQA 1WEOA 2I50A 2LQ6A 2G45A 2YUCA 5H1VA 4F52B 4YC9A 1N87A 5G05B 5G0FA 2EGPA 2F6JA 3N9PA 5D1MB 4XI1A 2RSDA 2K4DA 5TRBA 4YATA 4S3OB 2ECVA 3O36A 2JMDA 4AYCB 2KFTA 4IC3A 1VYXA 5B78A 3L11A 2VJFB 3KQIA 2MD8C 2MIQA 3MHHA 5TBNA 2XB1A 3DQVR 2L43A 5H1UA 3LQHA 3KV5A 2YHOA 4YBTA 2YQMA 3LQIA 2YW8A 3O37A 1WILA 2VJEA 4AUQB 5KH9A 1U6GB 2LRIC 4I7DA 2Y1MA 5FERA 4MSXA 5DKAA 5J3XA 1DVPA 4R2YA 3C5KA 1HYJA 3ZPV1 3VK6A 5TDRA 3N9NA 5LKTA 1MM2A 4A0CD 3L1ZB 4YBMA 5H1TA 2CT2A 4AYCA 2KGGA 4WZ3B 3SOXA 2VJFA 4WZ2A 2K16A 2LGGA 4ZUXU 4L58A 4QF3A 4UI9B 3LQJA 2VPBA 2DX8A 2H0DB 4A49A 1Z2QA 2LXHC 3IHPA 1G25A 4LKAA 2KE1A 2BAYA 3PUQA 2KWOA 2KU3A 3U5NA 3EB5A 4GNEA 4IC2A 1WEPA 3T7LA 1HYIA 1JOCA 2F42A 1JM7B 1WEQA 1WESA 4A4CA 2L80A 4WA6A 4WZ0A 1BORA 2NAAA 1F62A 4GNFA 2MA5A 1VD4A 2JMIA 2K17A 4YBSA 2UZGA 1XWHA 3ZTGA 3PHDA 3QZVA 2VNFA 3HCSA 4S3OC 1WE9A 2HDPA 5LKXA 3LRQA 5DINA 4ZDTA 5AIUA 3PURA 4PPEA 2M3HA 4R8PK 4MVTA 2YSJA 4TKPB 1WIMA 2E6SA 3ZNIA 2VPEA 4YAXA 3SOUA 4B86C 1X4UA 3M62A 2ECJA 2YHNA 2KYUA 2KREA 3SHBA 2OXQC 3ZVZB 4AVXA 1ZBDB 3RTRB 3T6RA 2MA6A 5LKUA 4B7YC 2PNXA 2H0DA 2KGIA 2QICA 2QIZA 4W4UA 2G6QA 5B79A 1CHCA 1JM7A 2C2VS 4N3WA 2F6NA 4FK5A 2VP7A 2YQLA 5G04B 3O33A 2KWKA 1FBVA 3GV4A 3NG2A 2LGVA 3U5MA 2Y1NA 5B8DA 1WEVA 2L0BA 1X4IA 1WGMA 4ZQLA 2MD7B 4NN2A 5KH7A 1IYMA 4CA1A 5C13A 5TABA 4LJNA 3EB6A 3ZVYA 2C2LA 1WENA 1MM3A 2FSAA 2M1RA 3O7AA 2FUIA 2KIZA 3FL2A 3DPLR 3RPGB 4BHWA 4FO9A 3N9MA 4A4BA 4QF2A 5FB0A 3GL6A 2CKLB 4PTBA 2YU4A 2CSYA 2L5UA 3KNVA 1WEUA 3L1XA 2KWNA 2KWJA 2LGKA 1WEWA 2ECWA 4GB0A 3M99A 2ECGA 1WEEA 4YABA 2D8SA 5KH3A 1RMDA 2EODA 2E6RA 1Z60A 2VPDA 4V3LC 3N9OA 5FEYA 1T1HA 3ZPVE 2JRJA 3V43A 2RI7A 1V87A 1LDKC 5D1KB 2AN6A 4LK9A 4UP0A 2JMJA 5H9MA 5C11A 4GNGA 5LCWB 2CKLA 1WFKA 4O64A 3N9QA 4I7CA 2MNZA 4V3KC 2MUMA 2VPGA 2ZETC 4LADB 2M85A 3U5PA 3KV6A 4N4FA 2YREA 5D1LB 2L75A 2KR4A 2LDRA 1VFYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ECI A;  1K2F A;  1FP0 A;  5TDW A;  3C6W A;  2YYR A;  2LN0 A;  3ASL A;  2XEU A;  3HCU A;  4CCG X;  1Z6U A;  3HCT A;  4LLB A;  4GND A;  1WEM A;  2EA6 A;  4BBQ A;  5B77 A;  4C9Z A;  2CSZ A;  2MT5 A;  2HYE D;  3HTK C;  3N9L A;  4I7B A;  3RPG C;  2MNY A;  4UP5 A;  2K1J A;  2ECT A;  1E4U A;  3O70 A;  4AP4 A;  2ECN A;  5FB1 A;  1LDJ B;  4FIP A;  2LXP C;  2QJ0 A;  5LKZ A;  2YSM A;  5B75 A;  2Y43 A;  2M6M A;  4FJC A;  2IDA A;  2FUU A;  3I2D A;  2LV9 A;  2G43 A;  4YAD A;  5EYA F;  3M63 A;  2YUR A;  4R7E A;  2YT5 A;  4L7X A;  4Q6F A;  5B76 A;  3O35 A;  4X3G A;  5AIT A;  2LGL A;  2VJE B;  3MHS A;  3O34 A;  5JG6 A;  1X4J A;  4P5O B;  3U5O A;  2PUY A;  5I3L A;  3SOW A;  3ZYQ A;  1WEO A;  2I50 A;  2LQ6 A;  2G45 A;  2YUC A;  5H1V A;  4F52 B;  4YC9 A;  1N87 A;  5G05 B;  5G0F A;  2EGP A;  2F6J A;  3N9P A;  5D1M B;  4XI1 A;  2RSD A;  2K4D A;  5TRB A;  4YAT A;  4S3O B;  2ECV A;  3O36 A;  2JMD A;  4AYC B;  2KFT A;  4IC3 A;  1VYX A;  5B78 A;  3L11 A;  2VJF B;  3KQI A;  2MD8 C;  2MIQ A;  3MHH A;  5TBN A;  2XB1 A;  3DQV R;  2L43 A;  5H1U A;  3LQH A;  3KV5 A;  2YHO A;  4YBT A;  2YQM A;  3LQI A;  2YW8 A;  3O37 A;  1WIL A;  2VJE A;  4AUQ B;  5KH9 A;  1U6G B;  2LRI C;  4I7D A;  2Y1M A;  5FER A;  4MSX A;  5DKA A;  5J3X A;  1DVP A;  4R2Y A;  3C5K A;  1HYJ A;  3ZPV 1;  3VK6 A;  5TDR A;  3N9N A;  5LKT A;  1MM2 A;  4A0C D;  3L1Z B;  4YBM A;  5H1T A;  2CT2 A;  4AYC A;  2KGG A;  4WZ3 B;  3SOX A;  2VJF A;  4WZ2 A;  2K16 A;  2LGG A;  4ZUX U;  4L58 A;  4QF3 A;  4UI9 B;  3LQJ A;  2VPB A;  2DX8 A;  2H0D B;  4A49 A;  1Z2Q A;  2LXH C;  3IHP A;  1G25 A;  4LKA A;  2KE1 A;  2BAY A;  3PUQ A;  2KWO A;  2KU3 A;  3U5N A;  3EB5 A;  4GNE A;  4IC2 A;  1WEP A;  3T7L A;  1HYI A;  1JOC A;  2F42 A;  1JM7 B;  1WEQ A;  1WES A;  4A4C A;  2L80 A;  4WA6 A;  4WZ0 A;  1BOR A;  2NAA A;  1F62 A;  4GNF A;  2MA5 A;  1VD4 A;  2JMI A;  2K17 A;  4YBS A;  2UZG A;  1XWH A;  3ZTG A;  3PHD A;  3QZV A;  2VNF A;  3HCS A;  4S3O C;  1WE9 A;  2HDP A;  5LKX A;  3LRQ A;  5DIN A;  4ZDT A;  5AIU A;  3PUR A;  4PPE A;  2M3H A;  4R8P K;  4MVT A;  2YSJ A;  4TKP B;  1WIM A;  2E6S A;  3ZNI A;  2VPE A;  4YAX A;  3SOU A;  4B86 C;  1X4U A;  3M62 A;  2ECJ A;  2YHN A;  2KYU A;  2KRE A;  3SHB A;  2OXQ C;  3ZVZ B;  4AVX A;  1ZBD B;  3RTR B;  3T6R A;  2MA6 A;  5LKU A;  4B7Y C;  2PNX A;  2H0D A;  2KGI A;  2QIC A;  2QIZ A;  4W4U A;  2G6Q A;  5B79 A;  1CHC A;  1JM7 A;  2C2V S;  4N3W A;  2F6N A;  4FK5 A;  2VP7 A;  2YQL A;  5G04 B;  3O33 A;  2KWK A;  1FBV A;  3GV4 A;  3NG2 A;  2LGV A;  3U5M A;  2Y1N A;  5B8D A;  1WEV A;  2L0B A;  1X4I A;  1WGM A;  4ZQL A;  2MD7 B;  4NN2 A;  5KH7 A;  1IYM A;  4CA1 A;  5C13 A;  5TAB A;  4LJN A;  3EB6 A;  3ZVY A;  2C2L A;  1WEN A;  1MM3 A;  2FSA A;  2M1R A;  3O7A A;  2FUI A;  2KIZ A;  3FL2 A;  3DPL R;  3RPG B;  4BHW A;  4FO9 A;  3N9M A;  4A4B A;  4QF2 A;  5FB0 A;  3GL6 A;  2CKL B;  4PTB A;  2YU4 A;  2CSY A;  2L5U A;  3KNV A;  1WEU A;  3L1X A;  2KWN A;  2KWJ A;  2LGK A;  1WEW A;  2ECW A;  4GB0 A;  3M99 A;  2ECG A;  1WEE A;  4YAB A;  2D8S A;  5KH3 A;  1RMD A;  2EOD A;  2E6R A;  1Z60 A;  2VPD A;  4V3L C;  3N9O A;  5FEY A;  1T1H A;  3ZPV E;  2JRJ A;  3V43 A;  2RI7 A;  1V87 A;  1LDK C;  5D1K B;  2AN6 A;  4LK9 A;  4UP0 A;  2JMJ A;  5H9M A;  5C11 A;  4GNG A;  5LCW B;  2CKL A;  1WFK A;  4O64 A;  3N9Q A;  4I7C A;  2MNZ A;  4V3K C;  2MUM A;  2VPG A;  2ZET C;  4LAD B;  2M85 A;  3U5P A;  3KV6 A;  4N4F A;  2YRE A;  5D1L B;  2L75 A;  2KR4 A;  2LDR A;  1VFY A; 
#chains in the Genus database with same CATH topology
 2ECI A;  1K2F A;  1FP0 A;  5TDW A;  3C6W A;  2YYR A;  2LN0 A;  3ASL A;  2XEU A;  3HCU A;  4CCG X;  1Z6U A;  3HCT A;  4LLB A;  4GND A;  1WEM A;  2EA6 A;  3MDB C;  4BBQ A;  5B77 A;  4C9Z A;  2XOC A;  2CSZ A;  2MT5 A;  2HYE D;  3HTK C;  3N9L A;  4I7B A;  3RPG C;  2MNY A;  4UP5 A;  4F1P A;  2K1J A;  2ECT A;  1E4U A;  2E61 A;  3O70 A;  4AP4 A;  2ECN A;  5FB1 A;  1LDJ B;  4FIP A;  2CON A;  2LXP C;  3O47 A;  2QJ0 A;  2CRW A;  5LKZ A;  2YSM A;  5B75 A;  3LVQ E;  2Y43 A;  2M6M A;  4FJC A;  2IDA A;  2FUU A;  3I2D A;  2LV9 A;  2G43 A;  4YAD A;  5EYA F;  3M63 A;  2YUR A;  3H7H A;  5SVY A;  3LJU X;  4R7E A;  2YT5 A;  4L7X A;  2EGM A;  4Q6F A;  5B76 A;  3O35 A;  4X3G A;  5AIT A;  2LGL A;  2VJE B;  3MHS A;  3O34 A;  5JG6 A;  1X4J A;  4P5O B;  5SVI B;  2YVR A;  3U5O A;  2PUY A;  5I3L A;  3SOW A;  3PLW A;  3ZYQ A;  1WEO A;  2I50 A;  2LQ6 A;  3SUB A;  2G45 A;  2YUC A;  5H1V A;  4F52 B;  4YC9 A;  1N87 A;  5G05 B;  5G0F A;  2DSM A;  2EGP A;  2F6J A;  3N9P A;  4OGE A;  5D1M B;  4XI1 A;  2RSD A;  2K4D A;  5TRB A;  4YAT A;  4S3O B;  2ECV A;  3O36 A;  2JMD A;  4AYC B;  2KFT A;  3DDT A;  1VYX A;  4IC3 A;  5B78 A;  3L11 A;  4O62 A;  2VJF B;  2JUN A;  3KQI A;  2MD8 C;  2MIQ A;  3MHH A;  5TBN A;  2XB1 A;  3DQV R;  2L43 A;  2L7P A;  5H1U A;  3LQH A;  3KV5 A;  2YHO A;  4YBT A;  2YQM A;  3LQI A;  2YW8 A;  3O37 A;  1WIL A;  2VJE A;  4AUQ B;  5KH9 A;  1U6G B;  2KKY A;  5SVI A;  2LRI C;  4I7D A;  2Y1M A;  5FER A;  4MSX A;  5DKA A;  5J3X A;  1DVP A;  3LVR E;  4R2Y A;  3C5K A;  1HYJ A;  3ZPV 1;  3VK6 A;  5TDR A;  3N9N A;  5LKT A;  1MM2 A;  4A0C D;  3L1Z B;  4YBM A;  5H1T A;  2CT2 A;  4AYC A;  2KGG A;  2FD4 A;  4WZ3 B;  3SOX A;  2VJF A;  4WZ2 A;  2K16 A;  2LGG A;  2LAU A;  4ZUX U;  4L58 A;  4QF3 A;  4UI9 B;  3LQJ A;  2VPB A;  3JUE A;  2DX8 A;  2H0D B;  4A49 A;  1Z2Q A;  2LXH C;  3IHP A;  1G25 A;  4LKA A;  2KE1 A;  2BAY A;  3PUQ A;  2KWO A;  3FM8 C;  2KU3 A;  3U5N A;  2OWA A;  3EB5 A;  4GNE A;  4IC2 A;  3M7K A;  1WEP A;  3T7L A;  1HYI A;  1JOC A;  2F42 A;  1JM7 B;  1WEQ A;  1WES A;  4A4C A;  2L80 A;  4WA6 A;  4WZ0 A;  1BOR A;  2NAA A;  1F62 A;  4GNF A;  2MA5 A;  1VD4 A;  2JMI A;  2K17 A;  4YBS A;  2UZG A;  2DJA A;  2KKX A;  1XWH A;  3ZTG A;  2IQJ A;  3PHD A;  3QZV A;  4QQ4 A;  2VNF A;  3HCS A;  4S3O C;  1WE9 A;  2HDP A;  5LKX A;  2MKE A;  3LRQ A;  5DIN A;  4ZDT A;  3FEH A;  5AIU A;  3PUR A;  4PPE A;  2M3H A;  4R8P K;  3DWD A;  4MVT A;  2YSJ A;  4TKP B;  1WIM A;  2E6S A;  3ZNI A;  2VPE A;  4YAX A;  4Z0R A;  3SOU A;  4B86 C;  1X4U A;  3M62 A;  2ECJ A;  5SVX A;  2YHN A;  2KYU A;  2KRE A;  3SHB A;  2OXQ C;  3ZVZ B;  4AVX A;  1ZBD B;  3RTR B;  3T6R A;  2MA6 A;  5LKU A;  4B7Y C;  2PNX A;  2H0D A;  2KGI A;  5K3Q A;  2QIC A;  2QIZ A;  4W4U A;  2G6Q A;  4Z0O A;  5B79 A;  1CHC A;  1JM7 A;  2C2V S;  4N3W A;  2F6N A;  3FAO A;  4FK5 A;  2VP7 A;  2YQL A;  5G04 B;  3O33 A;  2XOZ A;  2KWK A;  1FBV A;  2XOY A;  3GV4 A;  3NG2 A;  2LGV A;  3U5M A;  2D8U A;  2Y1N A;  3Q1D A;  5B8D A;  1WEV A;  2L0B A;  1X4I A;  1WGM A;  2JM3 A;  4ZQL A;  2MD7 B;  4OGC A;  2B0O E;  4NN2 A;  5KH7 A;  2M13 A;  1IYM A;  4CA1 A;  2P57 A;  5C13 A;  5TAB A;  2FFW A;  4LJN A;  3EB6 A;  2XP0 A;  3ZVY A;  2C2L A;  1WEN A;  1MM3 A;  2FSA A;  1MBM A;  2M1R A;  3O7A A;  2FUI A;  2KIZ A;  3FL2 A;  3DPL R;  3RPG B;  4BHW A;  4FO9 A;  3N9M A;  4A4B A;  4QF2 A;  5FB0 A;  3GL6 A;  2CKL B;  4PTB A;  2YU4 A;  2CSY A;  2L5U A;  3KNV A;  1WEU A;  3L1X A;  3FAN A;  2KWN A;  2KWJ A;  3KDE C;  4H9D A;  2LGK A;  1DCQ A;  1WEW A;  2ECW A;  4GB0 A;  3LDY A;  3M99 A;  2ECG A;  1WEE A;  4YAB A;  2D8S A;  5KH3 A;  1RMD A;  2EOD A;  3FJU B;  2E6R A;  1Z60 A;  2VPD A;  4V3L C;  3N9O A;  5FEY A;  1T1H A;  2EXU A;  2CRR A;  3ZPV E;  2JRJ A;  3V43 A;  2RI7 A;  2CSV A;  1V87 A;  1LDK C;  5D1K B;  2AN6 A;  4LK9 A;  4UP0 A;  2JMJ A;  5H9M A;  5C11 A;  4GNG A;  5LCW B;  2CKL A;  1WFK A;  4O64 A;  3N9Q A;  4I7C A;  2RR4 A;  2MNZ A;  4V3K C;  2MUM A;  2VPG A;  2ZET C;  4LAD B;  2M85 A;  3U5P A;  3KV6 A;  4N4F A;  2YRE A;  5D1L B;  2L75 A;  3E2D A;  2KR4 A;  2LDR A;  1VFY A;  3T9K A; 
#chains in the Genus database with same CATH homology
 2ECI A;  1K2F A;  1FP0 A;  5TDW A;  3C6W A;  2YYR A;  2LN0 A;  3ASL A;  2XEU A;  3HCU A;  4CCG X;  1Z6U A;  3HCT A;  4LLB A;  4GND A;  1WEM A;  2EA6 A;  4BBQ A;  5B77 A;  4C9Z A;  2CSZ A;  2MT5 A;  2HYE D;  3HTK C;  3N9L A;  4I7B A;  3RPG C;  2MNY A;  4UP5 A;  2K1J A;  2ECT A;  1E4U A;  3O70 A;  4AP4 A;  2ECN A;  5FB1 A;  1LDJ B;  4FIP A;  2LXP C;  2QJ0 A;  5LKZ A;  2YSM A;  5B75 A;  2Y43 A;  2M6M A;  4FJC A;  2IDA A;  2FUU A;  3I2D A;  2LV9 A;  2G43 A;  4YAD A;  5EYA F;  3M63 A;  2YUR A;  4R7E A;  2YT5 A;  4L7X A;  4Q6F A;  5B76 A;  3O35 A;  4X3G A;  5AIT A;  2LGL A;  2VJE B;  3MHS A;  3O34 A;  5JG6 A;  1X4J A;  4P5O B;  3U5O A;  2PUY A;  5I3L A;  3SOW A;  3ZYQ A;  1WEO A;  2I50 A;  2LQ6 A;  2G45 A;  2YUC A;  5H1V A;  4F52 B;  4YC9 A;  1N87 A;  5G05 B;  5G0F A;  2EGP A;  2F6J A;  3N9P A;  5D1M B;  4XI1 A;  2RSD A;  2K4D A;  5TRB A;  4YAT A;  4S3O B;  2ECV A;  3O36 A;  2JMD A;  4AYC B;  2KFT A;  4IC3 A;  1VYX A;  5B78 A;  3L11 A;  2VJF B;  3KQI A;  2MD8 C;  2MIQ A;  3MHH A;  5TBN A;  2XB1 A;  3DQV R;  2L43 A;  5H1U A;  3LQH A;  3KV5 A;  2YHO A;  4YBT A;  2YQM A;  3LQI A;  2YW8 A;  3O37 A;  1WIL A;  2VJE A;  4AUQ B;  5KH9 A;  1U6G B;  2LRI C;  4I7D A;  2Y1M A;  5FER A;  4MSX A;  5DKA A;  5J3X A;  1DVP A;  4R2Y A;  3C5K A;  1HYJ A;  3ZPV 1;  3VK6 A;  5TDR A;  3N9N A;  5LKT A;  1MM2 A;  4A0C D;  3L1Z B;  4YBM A;  5H1T A;  2CT2 A;  4AYC A;  2KGG A;  4WZ3 B;  3SOX A;  2VJF A;  4WZ2 A;  2K16 A;  2LGG A;  4ZUX U;  4L58 A;  4QF3 A;  4UI9 B;  3LQJ A;  2VPB A;  2DX8 A;  2H0D B;  4A49 A;  1Z2Q A;  2LXH C;  3IHP A;  1G25 A;  4LKA A;  2KE1 A;  2BAY A;  3PUQ A;  2KWO A;  2KU3 A;  3U5N A;  3EB5 A;  4GNE A;  4IC2 A;  1WEP A;  3T7L A;  1HYI A;  1JOC A;  2F42 A;  1JM7 B;  1WEQ A;  1WES A;  4A4C A;  2L80 A;  4WA6 A;  4WZ0 A;  1BOR A;  2NAA A;  1F62 A;  4GNF A;  2MA5 A;  1VD4 A;  2JMI A;  2K17 A;  4YBS A;  2UZG A;  1XWH A;  3ZTG A;  3PHD A;  3QZV A;  2VNF A;  3HCS A;  4S3O C;  1WE9 A;  2HDP A;  5LKX A;  3LRQ A;  5DIN A;  4ZDT A;  5AIU A;  3PUR A;  4PPE A;  2M3H A;  4R8P K;  4MVT A;  2YSJ A;  4TKP B;  1WIM A;  2E6S A;  3ZNI A;  2VPE A;  4YAX A;  3SOU A;  4B86 C;  1X4U A;  3M62 A;  2ECJ A;  2YHN A;  2KYU A;  2KRE A;  3SHB A;  2OXQ C;  3ZVZ B;  4AVX A;  1ZBD B;  3RTR B;  3T6R A;  2MA6 A;  5LKU A;  4B7Y C;  2PNX A;  2H0D A;  2KGI A;  2QIC A;  2QIZ A;  4W4U A;  2G6Q A;  5B79 A;  1CHC A;  1JM7 A;  2C2V S;  4N3W A;  2F6N A;  4FK5 A;  2VP7 A;  2YQL A;  5G04 B;  3O33 A;  2KWK A;  1FBV A;  3GV4 A;  3NG2 A;  2LGV A;  3U5M A;  2Y1N A;  5B8D A;  1WEV A;  2L0B A;  1X4I A;  1WGM A;  4ZQL A;  2MD7 B;  4NN2 A;  5KH7 A;  1IYM A;  4CA1 A;  5C13 A;  5TAB A;  4LJN A;  3EB6 A;  3ZVY A;  2C2L A;  1WEN A;  1MM3 A;  2FSA A;  2M1R A;  3O7A A;  2FUI A;  2KIZ A;  3FL2 A;  3DPL R;  3RPG B;  4BHW A;  4FO9 A;  3N9M A;  4A4B A;  4QF2 A;  5FB0 A;  3GL6 A;  2CKL B;  4PTB A;  2YU4 A;  2CSY A;  2L5U A;  3KNV A;  1WEU A;  3L1X A;  2KWN A;  2KWJ A;  2LGK A;  1WEW A;  2ECW A;  4GB0 A;  3M99 A;  2ECG A;  1WEE A;  4YAB A;  2D8S A;  5KH3 A;  1RMD A;  2EOD A;  2E6R A;  1Z60 A;  2VPD A;  4V3L C;  3N9O A;  5FEY A;  1T1H A;  3ZPV E;  2JRJ A;  3V43 A;  2RI7 A;  1V87 A;  1LDK C;  5D1K B;  2AN6 A;  4LK9 A;  4UP0 A;  2JMJ A;  5H9M A;  5C11 A;  4GNG A;  5LCW B;  2CKL A;  1WFK A;  4O64 A;  3N9Q A;  4I7C A;  2MNZ A;  4V3K C;  2MUM A;  2VPG A;  2ZET C;  4LAD B;  2M85 A;  3U5P A;  3KV6 A;  4N4F A;  2YRE A;  5D1L B;  2L75 A;  2KR4 A;  2LDR A;  1VFY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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