4Z0RA

Crystal structure of the cw domain of zcwpw2 mutant f78r in complex with histone h3 peptide
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
57
structure length
57
Chain Sequence
ENMYVNKVWVQCENENCLKWRLLSSEDSAKVDHDEPWYCFMNTDSRYNNCSISEEDR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the CW domain of ZCWPW2 mutant F78R in complex with histone H3 peptide
rcsb
molecule tags Protein binding/structural protein
source organism Homo sapiens
molecule keywords Zinc finger CW-type PWWP domain protein 2
total genus 10
structure length 57
sequence length 57
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2015-03-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07496 zf-CW CW-type Zinc Finger
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.100 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Herpes Virus-1 4z0rA00
4Z0RA 5SVYA 2RR4A 5SVIB 4QQ4A 5SVIA 2E61A 4Z0OA 5SVXA 4O62A 2L7PA
chains in the Genus database with same CATH superfamily
2LAUA 3QZVA 3RPGB 5DKAA 4W4UA 1G25A 4ZQLA 4A0CD 5B79A 3O34A 2KWOA 5KH3A 4GNGA 5FB0A 4MSXA 3C6WA 1XWHA 2K4DA 2L75A 3MDBC 2MIQA 3T9KA 3M63A 3JUEA 5FB1A 4XI1A 4QF2A 2CONA 3ZNIA 2F42A 1RMDA 3DWDA 3HCTA 2DX8A 3M7KA 3EB5A 4GNFA 3MHHA 2D8UA 2CT2A 1JOCA 2MNZA 2VJFB 3ZVZB 4TKPB 3ZYQA 2VJEB 2VPBA 3FEHA 2E61A 5B76A 5J3XA 2YW8A 1JM7B 3IHPA 1Z6UA 3O47A 2I50A 3EB6A 5KH7A 2DSMA 2VPGA 3LVRE 4AYCB 3N9NA 2Y1NA 3DQVR 2KWNA 4WA6A 3HTKC 4FK5A 5TABA 3SOXA 2HDPA 3O7AA 4P5OB 4WZ3B 2L0BA 4FIPA 2LGKA 4LJNA 2VPEA 2LXHC 5SVXA 2NAAA 2XB1A 4S3OB 4F52B 2KGIA 3N9MA 2LDRA 4L58A 4LKAA 3KNVA 3PHDA 2ECTA 1IYMA 2M13A 3T6RA 3RTRB 2FSAA 2YURA 4FJCA 4LADB 1WFKA 2KKYA 2RR4A 5K3QA 2D8SA 4L7XA 4LK9A 4AP4A 5SVIB 1WEMA 3O36A 2CSYA 4V3KC 5AIUA 4C9ZA 2YSJA 2RI7A 5JG6A 2YQLA 2F6JA 5B77A 5G0FA 1Z60A 2YVRA 4N3WA 4UI9B 2KR4A 2ECGA 4AVXA 2L5UA 3FAOA 3O37A 2BAYA 2XEUA 2EODA 2Y43A 5FEYA 4YC9A 2PNXA 2KGGA 2KWJA 1ZBDB 2B0OE 4Z0OA 3E2DA 3M62A 4R2YA 2H0DA 2LXPC 2LV9A 4FO9A 5TDWA 4YADA 1X4JA 2KIZA 3O35A 4BBQA 3ZVYA 2YREA 4O64A 3KV5A 1VD4A 3V43A 5C13A 5LKTA 3LQJA 5I3LA 2LGGA 5G05B 1K2FA 5TDRA 2AN6A 1FBVA 4WZ0A 2YHNA 2K1JA 3H7HA 3N9OA 3LVQE 3SOUA 4MVTA 2JUNA 4NN2A 3SUBA 5LKXA 2XOYA 2DJAA 4GB0A 2QJ0A 3FANA 3N9QA 3HCSA 3O70A 2ECJA 5B78A 2LGLA 3L11A 4I7CA 2MNYA 1HYIA 2YUCA 4PTBA 1WEVA 1LDJB 3ZTGA 2CKLA 4IC3A 3ZPVE 3ZPV1 2IQJA 3KDEC 4B7YC 2KFTA 3LRQA 4QQ4A 2JM3A 1DCQA 2EGMA 2L7PA 2YT5A 2G6QA 4LLBA 1N87A 2HYED 3N9PA 4CA1A 2LGVA 2KWKA 4UP0A 3ASLA 3Q1DA 3PUQA 2MA6A 2ECNA 2LRIC 2E6SA 4A4BA 4GNEA 1E4UA 3U5OA 4V3LC 3PLWA 1VFYA 3HCUA 2H0DB 4I7BA 1CHCA 1DVPA 2MUMA 4YAXA 4YABA 1VYXA 2MD8C 2KREA 3U5PA 5FERA 5AITA 4YBSA 5KH9A 1FP0A 4O62A 1HYJA 5B8DA 1Z2QA 3DDTA 3T7LA 2VNFA 3LJUX 4BHWA 1WENA 3GV4A 3M99A 2G43A 1WEQA 2VP7A 2IDAA 5D1LB 2JRJA 4Z0RA 3KQIA 5H9MA 4WZ2A 2MT5A 4R8PK 2M6MA 3FL2A 2M85A 1WILA 2QICA 4CCGX 2VPDA 5D1MB 3SOWA 4ZUXU 2C2VS 2MD7B 5DINA 2K16A 2XOCA 3RPGC 2XP0A 1WESA 2FUIA 2K17A 1WEWA 2CKLB 3MHSA 2MKEA 5H1VA 1F62A 1MM3A 2FFWA 3KV6A 4YATA 3U5MA 4F1PA 2C2LA 2ECWA 2M3HA 3LQHA 3N9LA 5EYAF 4OGEA 2EXUA 4OGCA 5B75A 2M1RA 1WEOA 2E6RA 5SVYA 5LCWB 3LDYA 1BORA 1WEPA 1MM2A 1V87A 2EGPA 2FUUA 4QF3A 5LKUA 2CSVA 2CSZA 2G45A 2JMDA 4ZDTA 2P57A 2ZETC 5TBNA 2EA6A 3GL6A 2VJFA 2YSMA 3NG2A 2OWAA 2VJEA 2JMIA 3FM8C 4A4CA 1JM7A 2YQMA 4A49A 4B86C 2KU3A 2F6NA 4UP5A 2JMJA 4AYCA 4Q6FA 1WEEA 3FJUB 4YBMA 2LQ6A 2MA5A 2UZGA 3C5KA 4S3OC 2L80A 4I7DA 5H1UA 3DPLR 4N4FA 5G04B 1MBMA 2KYUA 1X4UA 3U5NA 4YBTA 2KE1A 2FD4A 5H1TA 4R7EA 5D1KB 3PURA 2KKXA 2OXQC 1LDKC 1WEUA 1X4IA 2YHOA 4AUQB 2RSDA 2ECVA 3L1XA 2PUYA 5C11A 2YYRA 4GNDA 1WIMA 2YU4A 1WE9A 3I2DA 3O33A 1U6GB 1T1HA 5LKZA 2XOZA 2CRRA 3VK6A 1WGMA 4X3GA 4H9DA 2LN0A 3LQIA 4PPEA 5TRBA 5SVIA 2L43A 2CRWA 3L1ZB 2QIZA 3SHBA 2Y1MA 2ECIA 4IC2A
chains in the Genus database with same CATH topology
4F1PA 2P57A 2LAUA 3DWDA 3LJUX 4QQ4A 3PLWA 2JM3A 1DCQA 2EGMA 3M7KA 2YVRA 2L7PA 4OGEA 2EXUA 2M13A 4OGCA 2D8UA 2OWAA 2XOCA 3H7HA 2XP0A 2XOZA 2CRRA 3FM8C 2KKYA 2FD4A 4H9DA 4Z0RA 3MDBC 2RR4A 3LVQE 5SVYA 5K3QA 3LDYA 5SVIA 3FEHA 3T9KA 2E61A 2CRWA 2MKEA 2JUNA 3JUEA 3Q1DA 2YREA 2KKXA 4O62A 5SVXA 3SUBA 2IQJA 2CSVA 3DDTA 5SVIB 2XOYA 3KDEC 2B0OE 3O47A 2DJAA 3FJUB 4Z0OA 3E2DA 2CONA 2FFWA 3LVRE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z0R A;  5SVY A;  2RR4 A;  5SVI B;  4QQ4 A;  5SVI A;  2E61 A;  4Z0O A;  5SVX A;  4O62 A;  2L7P A; 
#chains in the Genus database with same CATH topology
 2LAU A;  3QZV A;  3RPG B;  5DKA A;  4W4U A;  1G25 A;  4ZQL A;  4A0C D;  5B79 A;  3O34 A;  2KWO A;  5KH3 A;  4GNG A;  5FB0 A;  4MSX A;  3C6W A;  1XWH A;  2K4D A;  2L75 A;  3MDB C;  2MIQ A;  3T9K A;  3M63 A;  3JUE A;  5FB1 A;  4XI1 A;  4QF2 A;  2CON A;  3ZNI A;  2F42 A;  1RMD A;  3DWD A;  3HCT A;  2DX8 A;  3M7K A;  3EB5 A;  4GNF A;  3MHH A;  2D8U A;  2CT2 A;  1JOC A;  2MNZ A;  2VJF B;  3ZVZ B;  4TKP B;  3ZYQ A;  2VJE B;  2VPB A;  3FEH A;  2E61 A;  5B76 A;  5J3X A;  2YW8 A;  1JM7 B;  3IHP A;  1Z6U A;  3O47 A;  2I50 A;  3EB6 A;  5KH7 A;  2DSM A;  2VPG A;  3LVR E;  4AYC B;  3N9N A;  2Y1N A;  3DQV R;  2KWN A;  4WA6 A;  3HTK C;  4FK5 A;  5TAB A;  3SOX A;  2HDP A;  3O7A A;  4P5O B;  4WZ3 B;  2L0B A;  4FIP A;  2LGK A;  4LJN A;  2VPE A;  2LXH C;  5SVX A;  2NAA A;  2XB1 A;  4S3O B;  4F52 B;  2KGI A;  3N9M A;  2LDR A;  4L58 A;  4LKA A;  3KNV A;  3PHD A;  2ECT A;  1IYM A;  2M13 A;  3T6R A;  3RTR B;  2FSA A;  2YUR A;  4FJC A;  4LAD B;  1WFK A;  2KKY A;  2RR4 A;  5K3Q A;  2D8S A;  4L7X A;  4LK9 A;  4AP4 A;  5SVI B;  1WEM A;  3O36 A;  2CSY A;  4V3K C;  5AIU A;  4C9Z A;  2YSJ A;  2RI7 A;  5JG6 A;  2YQL A;  2F6J A;  5B77 A;  5G0F A;  1Z60 A;  2YVR A;  4N3W A;  4UI9 B;  2KR4 A;  2ECG A;  4AVX A;  2L5U A;  3FAO A;  3O37 A;  2BAY A;  2XEU A;  2EOD A;  2Y43 A;  5FEY A;  4YC9 A;  2PNX A;  2KGG A;  2KWJ A;  1ZBD B;  2B0O E;  4Z0O A;  3E2D A;  3M62 A;  4R2Y A;  2H0D A;  2LXP C;  2LV9 A;  4FO9 A;  5TDW A;  4YAD A;  1X4J A;  2KIZ A;  3O35 A;  4BBQ A;  3ZVY A;  2YRE A;  4O64 A;  3KV5 A;  1VD4 A;  3V43 A;  5C13 A;  5LKT A;  3LQJ A;  5I3L A;  2LGG A;  5G05 B;  1K2F A;  5TDR A;  2AN6 A;  1FBV A;  4WZ0 A;  2YHN A;  2K1J A;  3H7H A;  3N9O A;  3LVQ E;  3SOU A;  4MVT A;  2JUN A;  4NN2 A;  3SUB A;  5LKX A;  2XOY A;  2DJA A;  4GB0 A;  2QJ0 A;  3FAN A;  3N9Q A;  3HCS A;  3O70 A;  2ECJ A;  5B78 A;  2LGL A;  3L11 A;  4I7C A;  2MNY A;  1HYI A;  2YUC A;  4PTB A;  1WEV A;  1LDJ B;  3ZTG A;  2CKL A;  4IC3 A;  3ZPV E;  3ZPV 1;  2IQJ A;  3KDE C;  4B7Y C;  2KFT A;  3LRQ A;  4QQ4 A;  2JM3 A;  1DCQ A;  2EGM A;  2L7P A;  2YT5 A;  2G6Q A;  4LLB A;  1N87 A;  2HYE D;  3N9P A;  4CA1 A;  2LGV A;  2KWK A;  4UP0 A;  3ASL A;  3Q1D A;  3PUQ A;  2MA6 A;  2ECN A;  2LRI C;  2E6S A;  4A4B A;  4GNE A;  1E4U A;  3U5O A;  4V3L C;  3PLW A;  1VFY A;  3HCU A;  2H0D B;  4I7B A;  1CHC A;  1DVP A;  2MUM A;  4YAX A;  4YAB A;  1VYX A;  2MD8 C;  2KRE A;  3U5P A;  5FER A;  5AIT A;  4YBS A;  5KH9 A;  1FP0 A;  4O62 A;  1HYJ A;  5B8D A;  1Z2Q A;  3DDT A;  3T7L A;  2VNF A;  3LJU X;  4BHW A;  1WEN A;  3GV4 A;  3M99 A;  2G43 A;  1WEQ A;  2VP7 A;  2IDA A;  5D1L B;  2JRJ A;  4Z0R A;  3KQI A;  5H9M A;  4WZ2 A;  2MT5 A;  4R8P K;  2M6M A;  3FL2 A;  2M85 A;  1WIL A;  2QIC A;  4CCG X;  2VPD A;  5D1M B;  3SOW A;  4ZUX U;  2C2V S;  2MD7 B;  5DIN A;  2K16 A;  2XOC A;  3RPG C;  2XP0 A;  1WES A;  2FUI A;  2K17 A;  1WEW A;  2CKL B;  3MHS A;  2MKE A;  5H1V A;  1F62 A;  1MM3 A;  2FFW A;  3KV6 A;  4YAT A;  3U5M A;  4F1P A;  2C2L A;  2ECW A;  2M3H A;  3LQH A;  3N9L A;  5EYA F;  4OGE A;  2EXU A;  4OGC A;  5B75 A;  2M1R A;  1WEO A;  2E6R A;  5SVY A;  5LCW B;  3LDY A;  1BOR A;  1WEP A;  1MM2 A;  1V87 A;  2EGP A;  2FUU A;  4QF3 A;  5LKU A;  2CSV A;  2CSZ A;  2G45 A;  2JMD A;  4ZDT A;  2P57 A;  2ZET C;  5TBN A;  2EA6 A;  3GL6 A;  2VJF A;  2YSM A;  3NG2 A;  2OWA A;  2VJE A;  2JMI A;  3FM8 C;  4A4C A;  1JM7 A;  2YQM A;  4A49 A;  4B86 C;  2KU3 A;  2F6N A;  4UP5 A;  2JMJ A;  4AYC A;  4Q6F A;  1WEE A;  3FJU B;  4YBM A;  2LQ6 A;  2MA5 A;  2UZG A;  3C5K A;  4S3O C;  2L80 A;  4I7D A;  5H1U A;  3DPL R;  4N4F A;  5G04 B;  1MBM A;  2KYU A;  1X4U A;  3U5N A;  4YBT A;  2KE1 A;  2FD4 A;  5H1T A;  4R7E A;  5D1K B;  3PUR A;  2KKX A;  2OXQ C;  1LDK C;  1WEU A;  1X4I A;  2YHO A;  4AUQ B;  2RSD A;  2ECV A;  3L1X A;  2PUY A;  5C11 A;  2YYR A;  4GND A;  1WIM A;  2YU4 A;  1WE9 A;  3I2D A;  3O33 A;  1U6G B;  1T1H A;  5LKZ A;  2XOZ A;  2CRR A;  3VK6 A;  1WGM A;  4X3G A;  4H9D A;  2LN0 A;  3LQI A;  4PPE A;  5TRB A;  5SVI A;  2L43 A;  2CRW A;  3L1Z B;  2QIZ A;  3SHB A;  2Y1M A;  2ECI A;  4IC2 A; 
#chains in the Genus database with same CATH homology
 4F1P A;  2P57 A;  2LAU A;  3DWD A;  3LJU X;  4QQ4 A;  3PLW A;  2JM3 A;  1DCQ A;  2EGM A;  3M7K A;  2YVR A;  2L7P A;  4OGE A;  2EXU A;  2M13 A;  4OGC A;  2D8U A;  2OWA A;  2XOC A;  3H7H A;  2XP0 A;  2XOZ A;  2CRR A;  3FM8 C;  2KKY A;  2FD4 A;  4H9D A;  4Z0R A;  3MDB C;  2RR4 A;  3LVQ E;  5SVY A;  5K3Q A;  3LDY A;  5SVI A;  3FEH A;  3T9K A;  2E61 A;  2CRW A;  2MKE A;  2JUN A;  3JUE A;  3Q1D A;  2YRE A;  2KKX A;  4O62 A;  5SVX A;  3SUB A;  2IQJ A;  2CSV A;  3DDT A;  5SVI B;  2XOY A;  3KDE C;  2B0O E;  3O47 A;  2DJA A;  3FJU B;  4Z0O A;  3E2D A;  2CON A;  2FFW A;  3LVR E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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