5B8DA

Crystal structure of a low occupancy fragment candidate (n-(4-methyl-1,3-thiazol-2-yl)propanamide) bound adjacent to the ubiquitin binding pocket of the hdac6 zinc-finger domain
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
99
structure length
99
Chain Sequence
PLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Histone deacetylase 6
total genus 32
structure length 99
sequence length 99
ec nomenclature ec 3.5.1.98: Histone deacetylase.
pdb deposition date 2016-06-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02148 zf-UBP Zn-finger in ubiquitin-hydrolases and other protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.10 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Zinc/RING finger domain, C3HC4 (zinc finger) 5b8dA00
3EB6A 2ECIA 2YU4A 4P5OB 2L80A 2HYED 4F52B 4R2YA 2KFTA 3GV4A 5AITA 4ZDTA 1X4JA 3ZVYA 5FB0A 2VPDA 3MHHA 4IC3A 4S3OC 4ZUXU 4C9ZA 2MA5A 2M6MA 5D1MB 1LDKC 3N9PA 2LGGA 2G45A 2YUCA 3EB5A 2KWOA 5LKUA 2C2VS 4I7CA 2XB1A 4A0CD 2KWNA 2QJ0A 4TKPB 3U5OA 3KV6A 3ZPVE 1WEWA 2HDPA 4GNDA 4B7YC 4QF2A 4LK9A 4AUQB 1VFYA 4V3LC 4BHWA 4WA6A 4WZ2A 4GNEA 5B77A 2VPBA 2YHNA 2CKLB 5H9MA 2MNYA 2PUYA 2LXPC 3PURA 1F62A 2OXQC 4PTBA 5D1KB 2QIZA 5DKAA 5TDRA 1LDJB 2L0BA 2KREA 3I2DA 2LRIC 4R7EA 4ZQLA 2L5UA 2M3HA 5LKTA 3GL6A 2H0DB 1V87A 4CA1A 2MNZA 1WEUA 4UI9B 2CKLA 2I50A 4I7DA 3QZVA 1WEEA 3ZNIA 3PUQA 2MUMA 1Z60A 2EA6A 2D8SA 3HCUA 3KNVA 4LKAA 2VJEB 2H0DA 1X4UA 2ECWA 2LQ6A 3T7LA 3SOUA 4V3KC 1WEPA 4GNGA 3LQIA 5KH7A 2KR4A 2KU3A 2JMIA 2ECNA 3O35A 2Y1MA 2KGGA 1WEVA 4WZ0A 2G43A 3ASLA 2YURA 4AYCB 3O7AA 5FB1A 4X3GA 3ZVZB 4LJNA 5G0FA 2VJEA 2LN0A 5I3LA 1FP0A 3O34A 2AN6A 2IDAA 2QICA 2C2LA 2VPEA 1U6GB 3MHSA 4IC2A 5H1TA 5J3XA 3DQVR 1JM7A 3NG2A 4W4UA 4NN2A 5TABA 4YBSA 4AYCA 1DVPA 2CSYA 2YSMA 1WEMA 3HCTA 1WESA 3O70A 2YQLA 3C5KA 2Y1NA 1T1HA 2FUIA 1K2FA 2DX8A 2XEUA 2ECJA 2JMDA 4YABA 4MVTA 5EYAF 4A49A 2KE1A 1VD4A 2VP7A 2JMJA 3N9OA 4CCGX 1MM3A 3L1ZB 5KH9A 2M1RA 4N3WA 3DPLR 3L11A 4YBMA 2E6RA 3FL2A 2LXHC 2KYUA 3O36A 5B8DA 2YW8A 2G6QA 5KH3A 2UZGA 4MSXA 4FO9A 5LKXA 1RMDA 2K16A 3RPGC 1WEOA 3VK6A 2LGVA 4FJCA 4GNFA 2FUUA 3O33A 2KGIA 4YBTA 2K17A 2L75A 1WFKA 2LGKA 4LLBA 3RPGB 3SHBA 5B78A 2F6NA 4PPEA 2YSJA 3U5PA 3V43A 2MT5A 3LRQA 1N87A 4YADA 2EODA 3M63A 3U5NA 4QF3A 2VNFA 2RI7A 1JM7B 5B79A 4BBQA 4A4CA 1WGMA 4LADB 1WEQA 5TDWA 1WE9A 1E4UA 1Z6UA 5B75A 5C11A 3T6RA 5G05B 2MD7B 5FEYA 2ZETC 2BAYA 1WIMA 4N4FA 3PHDA 2YQMA 5C13A 2NAAA 3N9MA 4XI1A 2Y43A 1JOCA 2YYRA 2MD8C 2KWKA 3SOXA 5LCWB 2F6JA 2M85A 2PNXA 4L7XA 3KQIA 4YC9A 2E6SA 2EGPA 1BORA 1WILA 5H1VA 2MIQA 4UP5A 4WZ3B 2VJFB 4Q6FA 2RSDA 5TBNA 2ECVA 2YHOA 1HYIA 3LQHA 4I7BA 1G25A 4AVXA 1WENA 2LV9A 5G04B 3HTKC 2K4DA 1X4IA 4S3OB 2KIZA 3M62A 2VJFA 2KWJA 5LKZA 5FERA 3N9NA 1VYXA 1CHCA 3KV5A 1MM2A 5H1UA 2CSZA 2FSAA 3O37A 3ZTGA 2LGLA 3LQJA 3C6WA 2F42A 4UP0A 5DINA 5B76A 3ZPV1 4YATA 2K1JA 1Z2QA 2ECTA 2YREA 5AIUA 5D1LB 3U5MA 2L43A 2VPGA 3N9QA 2JRJA 4B86C 2CT2A 2YT5A 1IYMA 3M99A 3L1XA 3RTRB 4AP4A 1FBVA 3N9LA 4L58A 4A4BA 1HYJA 4R8PK 3IHPA 3ZYQA 2ECGA 4YAXA 5TRBA 2LDRA 4O64A 4GB0A 1XWHA 5JG6A 3HCSA 4FK5A 3SOWA 4FIPA 2MA6A 1ZBDB
chains in the Genus database with same CATH superfamily
5SVXA 3EB6A 2ECIA 2YU4A 4P5OB 2L80A 2HYED 3KDEC 4F52B 4R2YA 2KFTA 3GV4A 5AITA 4ZDTA 4Z0OA 1X4JA 3ZVYA 5FB0A 2VPDA 3MHHA 4IC3A 4S3OC 4H9DA 4ZUXU 4C9ZA 2EGMA 4Z0RA 2MA5A 2M6MA 5D1MB 1LDKC 3N9PA 2LGGA 2G45A 2YUCA 3EB5A 2KWOA 2XOYA 5LKUA 2C2VS 4I7CA 2XB1A 4A0CD 2KWNA 2QJ0A 4TKPB 3U5OA 2RR4A 2D8UA 3KV6A 3ZPVE 1WEWA 2HDPA 4GNDA 4B7YC 4QF2A 4LK9A 4AUQB 1VFYA 4V3LC 4BHWA 4WA6A 4WZ2A 3DDTA 3DWDA 4GNEA 5B77A 2VPBA 2YHNA 2CKLB 5H9MA 2MNYA 2PUYA 2LXPC 3PURA 1F62A 2OXQC 4PTBA 5D1KB 2QIZA 5DKAA 5TDRA 1LDJB 2FD4A 2L0BA 2B0OE 2KREA 3I2DA 2CSVA 2DSMA 2LRIC 4R7EA 4ZQLA 2L5UA 2M3HA 5LKTA 2L7PA 3GL6A 2H0DB 1V87A 4CA1A 3FANA 2MNZA 1WEUA 4UI9B 2CKLA 2I50A 4I7DA 3QZVA 1WEEA 3ZNIA 3PUQA 2MUMA 3M7KA 1Z60A 2EA6A 2D8SA 3HCUA 3KNVA 4LKAA 2VJEB 2E61A 2H0DA 1X4UA 2ECWA 2LQ6A 3T7LA 3SOUA 4V3KC 1WEPA 4GNGA 3LQIA 5KH7A 2KR4A 2KU3A 2JMIA 2ECNA 3O35A 2Y1MA 2KGGA 1WEVA 4WZ0A 2G43A 3ASLA 3FJUB 2YURA 4AYCB 5SVYA 3O7AA 3Q1DA 5FB1A 4X3GA 3FM8C 3ZVZB 4LJNA 2FFWA 2XOZA 5G0FA 2VJEA 2KKYA 2LN0A 5I3LA 1FP0A 3O34A 2AN6A 2IDAA 3MDBC 2QICA 2C2LA 2VPEA 1U6GB 3MHSA 4IC2A 5H1TA 2DJAA 5J3XA 3DQVR 1JM7A 3NG2A 4W4UA 4NN2A 5TABA 4YBSA 4AYCA 1DVPA 2CSYA 2YSMA 1WEMA 3HCTA 1WESA 3O70A 2YQLA 4QQ4A 3C5KA 2Y1NA 3PLWA 1T1HA 2FUIA 1K2FA 2DX8A 2XEUA 2ECJA 2JMDA 4YABA 4MVTA 2CONA 5EYAF 4A49A 2KE1A 1VD4A 2VP7A 2JMJA 3N9OA 4CCGX 1MM3A 3L1ZB 5KH9A 2M1RA 4N3WA 5K3QA 3DPLR 3L11A 4YBMA 2E6RA 3FL2A 2LXHC 2KYUA 2XP0A 3O36A 2M13A 5B8DA 2YW8A 2G6QA 2CRWA 5KH3A 2JM3A 2CRRA 2UZGA 4MSXA 3O47A 4FO9A 5LKXA 1RMDA 2K16A 3RPGC 1WEOA 5SVIB 3VK6A 2LGVA 4FJCA 4GNFA 4O62A 2FUUA 3O33A 2KGIA 4YBTA 2K17A 2L75A 1MBMA 1WFKA 2LGKA 4LLBA 3RPGB 3LJUX 3SHBA 5B78A 2F6NA 4PPEA 2YSJA 3U5PA 5SVIA 3JUEA 3V43A 2MKEA 2MT5A 3LRQA 2OWAA 1N87A 4YADA 2EODA 3FAOA 3M63A 4OGEA 3U5NA 3H7HA 4QF3A 2P57A 2VNFA 3LVQE 2RI7A 1JM7B 5B79A 4BBQA 4A4CA 1WGMA 2KKXA 4LADB 1WEQA 5TDWA 1WE9A 1E4UA 1Z6UA 5B75A 5C11A 3T6RA 5G05B 2MD7B 5FEYA 2ZETC 2BAYA 1WIMA 4N4FA 3PHDA 2YQMA 5C13A 2NAAA 3N9MA 4XI1A 2Y43A 1JOCA 2IQJA 2YYRA 2MD8C 2JUNA 3T9KA 2KWKA 3SOXA 5LCWB 2F6JA 2M85A 2PNXA 4L7XA 3KQIA 4YC9A 2E6SA 2EGPA 1BORA 1WILA 5H1VA 2MIQA 4UP5A 4WZ3B 2VJFB 4Q6FA 2RSDA 5TBNA 2ECVA 2YHOA 1HYIA 3LQHA 4I7BA 1G25A 1DCQA 4OGCA 3FEHA 4AVXA 3SUBA 1WENA 2LV9A 5G04B 3HTKC 2K4DA 1X4IA 4S3OB 2KIZA 3M62A 2VJFA 2KWJA 5LKZA 5FERA 3N9NA 1VYXA 1CHCA 3KV5A 1MM2A 5H1UA 2CSZA 2FSAA 2XOCA 3LVRE 3O37A 4F1PA 3ZTGA 3LDYA 2LGLA 3LQJA 2YVRA 3C6WA 2F42A 4UP0A 5DINA 2EXUA 5B76A 3ZPV1 4YATA 2K1JA 1Z2QA 2ECTA 2YREA 5AIUA 5D1LB 3U5MA 2L43A 2VPGA 3N9QA 2JRJA 4B86C 2CT2A 2YT5A 1IYMA 3M99A 3L1XA 3RTRB 4AP4A 1FBVA 3N9LA 4L58A 4A4BA 1HYJA 4R8PK 3IHPA 3ZYQA 2ECGA 4YAXA 5TRBA 2LDRA 4O64A 4GB0A 3E2DA 1XWHA 5JG6A 3HCSA 4FK5A 3SOWA 4FIPA 2MA6A 1ZBDB 2LAUA
chains in the Genus database with same CATH topology
3EB6A 2ECIA 2YU4A 4P5OB 2L80A 2HYED 4F52B 4R2YA 2KFTA 3GV4A 5AITA 4ZDTA 1X4JA 3ZVYA 5FB0A 2VPDA 3MHHA 4IC3A 4S3OC 4ZUXU 4C9ZA 2MA5A 2M6MA 5D1MB 1LDKC 3N9PA 2LGGA 2G45A 2YUCA 3EB5A 2KWOA 5LKUA 2C2VS 4I7CA 2XB1A 4A0CD 2KWNA 2QJ0A 4TKPB 3U5OA 3KV6A 3ZPVE 1WEWA 2HDPA 4GNDA 4B7YC 4QF2A 4LK9A 4AUQB 1VFYA 4V3LC 4BHWA 4WA6A 4WZ2A 4GNEA 5B77A 2VPBA 2YHNA 2CKLB 5H9MA 2MNYA 2PUYA 2LXPC 3PURA 1F62A 2OXQC 4PTBA 5D1KB 2QIZA 5DKAA 5TDRA 1LDJB 2L0BA 2KREA 3I2DA 2LRIC 4R7EA 4ZQLA 2L5UA 2M3HA 5LKTA 3GL6A 2H0DB 1V87A 4CA1A 2MNZA 1WEUA 4UI9B 2CKLA 2I50A 4I7DA 3QZVA 1WEEA 3ZNIA 3PUQA 2MUMA 1Z60A 2EA6A 2D8SA 3HCUA 3KNVA 4LKAA 2VJEB 2H0DA 1X4UA 2ECWA 2LQ6A 3T7LA 3SOUA 4V3KC 1WEPA 4GNGA 3LQIA 5KH7A 2KR4A 2KU3A 2JMIA 2ECNA 3O35A 2Y1MA 2KGGA 1WEVA 4WZ0A 2G43A 3ASLA 2YURA 4AYCB 3O7AA 5FB1A 4X3GA 3ZVZB 4LJNA 5G0FA 2VJEA 2LN0A 5I3LA 1FP0A 3O34A 2AN6A 2IDAA 2QICA 2C2LA 2VPEA 1U6GB 3MHSA 4IC2A 5H1TA 5J3XA 3DQVR 1JM7A 3NG2A 4W4UA 4NN2A 5TABA 4YBSA 4AYCA 1DVPA 2CSYA 2YSMA 1WEMA 3HCTA 1WESA 3O70A 2YQLA 3C5KA 2Y1NA 1T1HA 2FUIA 1K2FA 2DX8A 2XEUA 2ECJA 2JMDA 4YABA 4MVTA 5EYAF 4A49A 2KE1A 1VD4A 2VP7A 2JMJA 3N9OA 4CCGX 1MM3A 3L1ZB 5KH9A 2M1RA 4N3WA 3DPLR 3L11A 4YBMA 2E6RA 3FL2A 2LXHC 2KYUA 3O36A 5B8DA 2YW8A 2G6QA 5KH3A 2UZGA 4MSXA 4FO9A 5LKXA 1RMDA 2K16A 3RPGC 1WEOA 3VK6A 2LGVA 4FJCA 4GNFA 2FUUA 3O33A 2KGIA 4YBTA 2K17A 2L75A 1WFKA 2LGKA 4LLBA 3RPGB 3SHBA 5B78A 2F6NA 4PPEA 2YSJA 3U5PA 3V43A 2MT5A 3LRQA 1N87A 4YADA 2EODA 3M63A 3U5NA 4QF3A 2VNFA 2RI7A 1JM7B 5B79A 4BBQA 4A4CA 1WGMA 4LADB 1WEQA 5TDWA 1WE9A 1E4UA 1Z6UA 5B75A 5C11A 3T6RA 5G05B 2MD7B 5FEYA 2ZETC 2BAYA 1WIMA 4N4FA 3PHDA 2YQMA 5C13A 2NAAA 3N9MA 4XI1A 2Y43A 1JOCA 2YYRA 2MD8C 2KWKA 3SOXA 5LCWB 2F6JA 2M85A 2PNXA 4L7XA 3KQIA 4YC9A 2E6SA 2EGPA 1BORA 1WILA 5H1VA 2MIQA 4UP5A 4WZ3B 2VJFB 4Q6FA 2RSDA 5TBNA 2ECVA 2YHOA 1HYIA 3LQHA 4I7BA 1G25A 4AVXA 1WENA 2LV9A 5G04B 3HTKC 2K4DA 1X4IA 4S3OB 2KIZA 3M62A 2VJFA 2KWJA 5LKZA 5FERA 3N9NA 1VYXA 1CHCA 3KV5A 1MM2A 5H1UA 2CSZA 2FSAA 3O37A 3ZTGA 2LGLA 3LQJA 3C6WA 2F42A 4UP0A 5DINA 5B76A 3ZPV1 4YATA 2K1JA 1Z2QA 2ECTA 2YREA 5AIUA 5D1LB 3U5MA 2L43A 2VPGA 3N9QA 2JRJA 4B86C 2CT2A 2YT5A 1IYMA 3M99A 3L1XA 3RTRB 4AP4A 1FBVA 3N9LA 4L58A 4A4BA 1HYJA 4R8PK 3IHPA 3ZYQA 2ECGA 4YAXA 5TRBA 2LDRA 4O64A 4GB0A 1XWHA 5JG6A 3HCSA 4FK5A 3SOWA 4FIPA 2MA6A 1ZBDB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EB6 A;  2ECI A;  2YU4 A;  4P5O B;  2L80 A;  2HYE D;  4F52 B;  4R2Y A;  2KFT A;  3GV4 A;  5AIT A;  4ZDT A;  1X4J A;  3ZVY A;  5FB0 A;  2VPD A;  3MHH A;  4IC3 A;  4S3O C;  4ZUX U;  4C9Z A;  2MA5 A;  2M6M A;  5D1M B;  1LDK C;  3N9P A;  2LGG A;  2G45 A;  2YUC A;  3EB5 A;  2KWO A;  5LKU A;  2C2V S;  4I7C A;  2XB1 A;  4A0C D;  2KWN A;  2QJ0 A;  4TKP B;  3U5O A;  3KV6 A;  3ZPV E;  1WEW A;  2HDP A;  4GND A;  4B7Y C;  4QF2 A;  4LK9 A;  4AUQ B;  1VFY A;  4V3L C;  4BHW A;  4WA6 A;  4WZ2 A;  4GNE A;  5B77 A;  2VPB A;  2YHN A;  2CKL B;  5H9M A;  2MNY A;  2PUY A;  2LXP C;  3PUR A;  1F62 A;  2OXQ C;  4PTB A;  5D1K B;  2QIZ A;  5DKA A;  5TDR A;  1LDJ B;  2L0B A;  2KRE A;  3I2D A;  2LRI C;  4R7E A;  4ZQL A;  2L5U A;  2M3H A;  5LKT A;  3GL6 A;  2H0D B;  1V87 A;  4CA1 A;  2MNZ A;  1WEU A;  4UI9 B;  2CKL A;  2I50 A;  4I7D A;  3QZV A;  1WEE A;  3ZNI A;  3PUQ A;  2MUM A;  1Z60 A;  2EA6 A;  2D8S A;  3HCU A;  3KNV A;  4LKA A;  2VJE B;  2H0D A;  1X4U A;  2ECW A;  2LQ6 A;  3T7L A;  3SOU A;  4V3K C;  1WEP A;  4GNG A;  3LQI A;  5KH7 A;  2KR4 A;  2KU3 A;  2JMI A;  2ECN A;  3O35 A;  2Y1M A;  2KGG A;  1WEV A;  4WZ0 A;  2G43 A;  3ASL A;  2YUR A;  4AYC B;  3O7A A;  5FB1 A;  4X3G A;  3ZVZ B;  4LJN A;  5G0F A;  2VJE A;  2LN0 A;  5I3L A;  1FP0 A;  3O34 A;  2AN6 A;  2IDA A;  2QIC A;  2C2L A;  2VPE A;  1U6G B;  3MHS A;  4IC2 A;  5H1T A;  5J3X A;  3DQV R;  1JM7 A;  3NG2 A;  4W4U A;  4NN2 A;  5TAB A;  4YBS A;  4AYC A;  1DVP A;  2CSY A;  2YSM A;  1WEM A;  3HCT A;  1WES A;  3O70 A;  2YQL A;  3C5K A;  2Y1N A;  1T1H A;  2FUI A;  1K2F A;  2DX8 A;  2XEU A;  2ECJ A;  2JMD A;  4YAB A;  4MVT A;  5EYA F;  4A49 A;  2KE1 A;  1VD4 A;  2VP7 A;  2JMJ A;  3N9O A;  4CCG X;  1MM3 A;  3L1Z B;  5KH9 A;  2M1R A;  4N3W A;  3DPL R;  3L11 A;  4YBM A;  2E6R A;  3FL2 A;  2LXH C;  2KYU A;  3O36 A;  5B8D A;  2YW8 A;  2G6Q A;  5KH3 A;  2UZG A;  4MSX A;  4FO9 A;  5LKX A;  1RMD A;  2K16 A;  3RPG C;  1WEO A;  3VK6 A;  2LGV A;  4FJC A;  4GNF A;  2FUU A;  3O33 A;  2KGI A;  4YBT A;  2K17 A;  2L75 A;  1WFK A;  2LGK A;  4LLB A;  3RPG B;  3SHB A;  5B78 A;  2F6N A;  4PPE A;  2YSJ A;  3U5P A;  3V43 A;  2MT5 A;  3LRQ A;  1N87 A;  4YAD A;  2EOD A;  3M63 A;  3U5N A;  4QF3 A;  2VNF A;  2RI7 A;  1JM7 B;  5B79 A;  4BBQ A;  4A4C A;  1WGM A;  4LAD B;  1WEQ A;  5TDW A;  1WE9 A;  1E4U A;  1Z6U A;  5B75 A;  5C11 A;  3T6R A;  5G05 B;  2MD7 B;  5FEY A;  2ZET C;  2BAY A;  1WIM A;  4N4F A;  3PHD A;  2YQM A;  5C13 A;  2NAA A;  3N9M A;  4XI1 A;  2Y43 A;  1JOC A;  2YYR A;  2MD8 C;  2KWK A;  3SOX A;  5LCW B;  2F6J A;  2M85 A;  2PNX A;  4L7X A;  3KQI A;  4YC9 A;  2E6S A;  2EGP A;  1BOR A;  1WIL A;  5H1V A;  2MIQ A;  4UP5 A;  4WZ3 B;  2VJF B;  4Q6F A;  2RSD A;  5TBN A;  2ECV A;  2YHO A;  1HYI A;  3LQH A;  4I7B A;  1G25 A;  4AVX A;  1WEN A;  2LV9 A;  5G04 B;  3HTK C;  2K4D A;  1X4I A;  4S3O B;  2KIZ A;  3M62 A;  2VJF A;  2KWJ A;  5LKZ A;  5FER A;  3N9N A;  1VYX A;  1CHC A;  3KV5 A;  1MM2 A;  5H1U A;  2CSZ A;  2FSA A;  3O37 A;  3ZTG A;  2LGL A;  3LQJ A;  3C6W A;  2F42 A;  4UP0 A;  5DIN A;  5B76 A;  3ZPV 1;  4YAT A;  2K1J A;  1Z2Q A;  2ECT A;  2YRE A;  5AIU A;  5D1L B;  3U5M A;  2L43 A;  2VPG A;  3N9Q A;  2JRJ A;  4B86 C;  2CT2 A;  2YT5 A;  1IYM A;  3M99 A;  3L1X A;  3RTR B;  4AP4 A;  1FBV A;  3N9L A;  4L58 A;  4A4B A;  1HYJ A;  4R8P K;  3IHP A;  3ZYQ A;  2ECG A;  4YAX A;  5TRB A;  2LDR A;  4O64 A;  4GB0 A;  1XWH A;  5JG6 A;  3HCS A;  4FK5 A;  3SOW A;  4FIP A;  2MA6 A;  1ZBD B; 
#chains in the Genus database with same CATH topology
 5SVX A;  3EB6 A;  2ECI A;  2YU4 A;  4P5O B;  2L80 A;  2HYE D;  3KDE C;  4F52 B;  4R2Y A;  2KFT A;  3GV4 A;  5AIT A;  4ZDT A;  4Z0O A;  1X4J A;  3ZVY A;  5FB0 A;  2VPD A;  3MHH A;  4IC3 A;  4S3O C;  4H9D A;  4ZUX U;  4C9Z A;  2EGM A;  4Z0R A;  2MA5 A;  2M6M A;  5D1M B;  1LDK C;  3N9P A;  2LGG A;  2G45 A;  2YUC A;  3EB5 A;  2KWO A;  2XOY A;  5LKU A;  2C2V S;  4I7C A;  2XB1 A;  4A0C D;  2KWN A;  2QJ0 A;  4TKP B;  3U5O A;  2RR4 A;  2D8U A;  3KV6 A;  3ZPV E;  1WEW A;  2HDP A;  4GND A;  4B7Y C;  4QF2 A;  4LK9 A;  4AUQ B;  1VFY A;  4V3L C;  4BHW A;  4WA6 A;  4WZ2 A;  3DDT A;  3DWD A;  4GNE A;  5B77 A;  2VPB A;  2YHN A;  2CKL B;  5H9M A;  2MNY A;  2PUY A;  2LXP C;  3PUR A;  1F62 A;  2OXQ C;  4PTB A;  5D1K B;  2QIZ A;  5DKA A;  5TDR A;  1LDJ B;  2FD4 A;  2L0B A;  2B0O E;  2KRE A;  3I2D A;  2CSV A;  2DSM A;  2LRI C;  4R7E A;  4ZQL A;  2L5U A;  2M3H A;  5LKT A;  2L7P A;  3GL6 A;  2H0D B;  1V87 A;  4CA1 A;  3FAN A;  2MNZ A;  1WEU A;  4UI9 B;  2CKL A;  2I50 A;  4I7D A;  3QZV A;  1WEE A;  3ZNI A;  3PUQ A;  2MUM A;  3M7K A;  1Z60 A;  2EA6 A;  2D8S A;  3HCU A;  3KNV A;  4LKA A;  2VJE B;  2E61 A;  2H0D A;  1X4U A;  2ECW A;  2LQ6 A;  3T7L A;  3SOU A;  4V3K C;  1WEP A;  4GNG A;  3LQI A;  5KH7 A;  2KR4 A;  2KU3 A;  2JMI A;  2ECN A;  3O35 A;  2Y1M A;  2KGG A;  1WEV A;  4WZ0 A;  2G43 A;  3ASL A;  3FJU B;  2YUR A;  4AYC B;  5SVY A;  3O7A A;  3Q1D A;  5FB1 A;  4X3G A;  3FM8 C;  3ZVZ B;  4LJN A;  2FFW A;  2XOZ A;  5G0F A;  2VJE A;  2KKY A;  2LN0 A;  5I3L A;  1FP0 A;  3O34 A;  2AN6 A;  2IDA A;  3MDB C;  2QIC A;  2C2L A;  2VPE A;  1U6G B;  3MHS A;  4IC2 A;  5H1T A;  2DJA A;  5J3X A;  3DQV R;  1JM7 A;  3NG2 A;  4W4U A;  4NN2 A;  5TAB A;  4YBS A;  4AYC A;  1DVP A;  2CSY A;  2YSM A;  1WEM A;  3HCT A;  1WES A;  3O70 A;  2YQL A;  4QQ4 A;  3C5K A;  2Y1N A;  3PLW A;  1T1H A;  2FUI A;  1K2F A;  2DX8 A;  2XEU A;  2ECJ A;  2JMD A;  4YAB A;  4MVT A;  2CON A;  5EYA F;  4A49 A;  2KE1 A;  1VD4 A;  2VP7 A;  2JMJ A;  3N9O A;  4CCG X;  1MM3 A;  3L1Z B;  5KH9 A;  2M1R A;  4N3W A;  5K3Q A;  3DPL R;  3L11 A;  4YBM A;  2E6R A;  3FL2 A;  2LXH C;  2KYU A;  2XP0 A;  3O36 A;  2M13 A;  5B8D A;  2YW8 A;  2G6Q A;  2CRW A;  5KH3 A;  2JM3 A;  2CRR A;  2UZG A;  4MSX A;  3O47 A;  4FO9 A;  5LKX A;  1RMD A;  2K16 A;  3RPG C;  1WEO A;  5SVI B;  3VK6 A;  2LGV A;  4FJC A;  4GNF A;  4O62 A;  2FUU A;  3O33 A;  2KGI A;  4YBT A;  2K17 A;  2L75 A;  1MBM A;  1WFK A;  2LGK A;  4LLB A;  3RPG B;  3LJU X;  3SHB A;  5B78 A;  2F6N A;  4PPE A;  2YSJ A;  3U5P A;  5SVI A;  3JUE A;  3V43 A;  2MKE A;  2MT5 A;  3LRQ A;  2OWA A;  1N87 A;  4YAD A;  2EOD A;  3FAO A;  3M63 A;  4OGE A;  3U5N A;  3H7H A;  4QF3 A;  2P57 A;  2VNF A;  3LVQ E;  2RI7 A;  1JM7 B;  5B79 A;  4BBQ A;  4A4C A;  1WGM A;  2KKX A;  4LAD B;  1WEQ A;  5TDW A;  1WE9 A;  1E4U A;  1Z6U A;  5B75 A;  5C11 A;  3T6R A;  5G05 B;  2MD7 B;  5FEY A;  2ZET C;  2BAY A;  1WIM A;  4N4F A;  3PHD A;  2YQM A;  5C13 A;  2NAA A;  3N9M A;  4XI1 A;  2Y43 A;  1JOC A;  2IQJ A;  2YYR A;  2MD8 C;  2JUN A;  3T9K A;  2KWK A;  3SOX A;  5LCW B;  2F6J A;  2M85 A;  2PNX A;  4L7X A;  3KQI A;  4YC9 A;  2E6S A;  2EGP A;  1BOR A;  1WIL A;  5H1V A;  2MIQ A;  4UP5 A;  4WZ3 B;  2VJF B;  4Q6F A;  2RSD A;  5TBN A;  2ECV A;  2YHO A;  1HYI A;  3LQH A;  4I7B A;  1G25 A;  1DCQ A;  4OGC A;  3FEH A;  4AVX A;  3SUB A;  1WEN A;  2LV9 A;  5G04 B;  3HTK C;  2K4D A;  1X4I A;  4S3O B;  2KIZ A;  3M62 A;  2VJF A;  2KWJ A;  5LKZ A;  5FER A;  3N9N A;  1VYX A;  1CHC A;  3KV5 A;  1MM2 A;  5H1U A;  2CSZ A;  2FSA A;  2XOC A;  3LVR E;  3O37 A;  4F1P A;  3ZTG A;  3LDY A;  2LGL A;  3LQJ A;  2YVR A;  3C6W A;  2F42 A;  4UP0 A;  5DIN A;  2EXU A;  5B76 A;  3ZPV 1;  4YAT A;  2K1J A;  1Z2Q A;  2ECT A;  2YRE A;  5AIU A;  5D1L B;  3U5M A;  2L43 A;  2VPG A;  3N9Q A;  2JRJ A;  4B86 C;  2CT2 A;  2YT5 A;  1IYM A;  3M99 A;  3L1X A;  3RTR B;  4AP4 A;  1FBV A;  3N9L A;  4L58 A;  4A4B A;  1HYJ A;  4R8P K;  3IHP A;  3ZYQ A;  2ECG A;  4YAX A;  5TRB A;  2LDR A;  4O64 A;  4GB0 A;  3E2D A;  1XWH A;  5JG6 A;  3HCS A;  4FK5 A;  3SOW A;  4FIP A;  2MA6 A;  1ZBD B;  2LAU A; 
#chains in the Genus database with same CATH homology
 3EB6 A;  2ECI A;  2YU4 A;  4P5O B;  2L80 A;  2HYE D;  4F52 B;  4R2Y A;  2KFT A;  3GV4 A;  5AIT A;  4ZDT A;  1X4J A;  3ZVY A;  5FB0 A;  2VPD A;  3MHH A;  4IC3 A;  4S3O C;  4ZUX U;  4C9Z A;  2MA5 A;  2M6M A;  5D1M B;  1LDK C;  3N9P A;  2LGG A;  2G45 A;  2YUC A;  3EB5 A;  2KWO A;  5LKU A;  2C2V S;  4I7C A;  2XB1 A;  4A0C D;  2KWN A;  2QJ0 A;  4TKP B;  3U5O A;  3KV6 A;  3ZPV E;  1WEW A;  2HDP A;  4GND A;  4B7Y C;  4QF2 A;  4LK9 A;  4AUQ B;  1VFY A;  4V3L C;  4BHW A;  4WA6 A;  4WZ2 A;  4GNE A;  5B77 A;  2VPB A;  2YHN A;  2CKL B;  5H9M A;  2MNY A;  2PUY A;  2LXP C;  3PUR A;  1F62 A;  2OXQ C;  4PTB A;  5D1K B;  2QIZ A;  5DKA A;  5TDR A;  1LDJ B;  2L0B A;  2KRE A;  3I2D A;  2LRI C;  4R7E A;  4ZQL A;  2L5U A;  2M3H A;  5LKT A;  3GL6 A;  2H0D B;  1V87 A;  4CA1 A;  2MNZ A;  1WEU A;  4UI9 B;  2CKL A;  2I50 A;  4I7D A;  3QZV A;  1WEE A;  3ZNI A;  3PUQ A;  2MUM A;  1Z60 A;  2EA6 A;  2D8S A;  3HCU A;  3KNV A;  4LKA A;  2VJE B;  2H0D A;  1X4U A;  2ECW A;  2LQ6 A;  3T7L A;  3SOU A;  4V3K C;  1WEP A;  4GNG A;  3LQI A;  5KH7 A;  2KR4 A;  2KU3 A;  2JMI A;  2ECN A;  3O35 A;  2Y1M A;  2KGG A;  1WEV A;  4WZ0 A;  2G43 A;  3ASL A;  2YUR A;  4AYC B;  3O7A A;  5FB1 A;  4X3G A;  3ZVZ B;  4LJN A;  5G0F A;  2VJE A;  2LN0 A;  5I3L A;  1FP0 A;  3O34 A;  2AN6 A;  2IDA A;  2QIC A;  2C2L A;  2VPE A;  1U6G B;  3MHS A;  4IC2 A;  5H1T A;  5J3X A;  3DQV R;  1JM7 A;  3NG2 A;  4W4U A;  4NN2 A;  5TAB A;  4YBS A;  4AYC A;  1DVP A;  2CSY A;  2YSM A;  1WEM A;  3HCT A;  1WES A;  3O70 A;  2YQL A;  3C5K A;  2Y1N A;  1T1H A;  2FUI A;  1K2F A;  2DX8 A;  2XEU A;  2ECJ A;  2JMD A;  4YAB A;  4MVT A;  5EYA F;  4A49 A;  2KE1 A;  1VD4 A;  2VP7 A;  2JMJ A;  3N9O A;  4CCG X;  1MM3 A;  3L1Z B;  5KH9 A;  2M1R A;  4N3W A;  3DPL R;  3L11 A;  4YBM A;  2E6R A;  3FL2 A;  2LXH C;  2KYU A;  3O36 A;  5B8D A;  2YW8 A;  2G6Q A;  5KH3 A;  2UZG A;  4MSX A;  4FO9 A;  5LKX A;  1RMD A;  2K16 A;  3RPG C;  1WEO A;  3VK6 A;  2LGV A;  4FJC A;  4GNF A;  2FUU A;  3O33 A;  2KGI A;  4YBT A;  2K17 A;  2L75 A;  1WFK A;  2LGK A;  4LLB A;  3RPG B;  3SHB A;  5B78 A;  2F6N A;  4PPE A;  2YSJ A;  3U5P A;  3V43 A;  2MT5 A;  3LRQ A;  1N87 A;  4YAD A;  2EOD A;  3M63 A;  3U5N A;  4QF3 A;  2VNF A;  2RI7 A;  1JM7 B;  5B79 A;  4BBQ A;  4A4C A;  1WGM A;  4LAD B;  1WEQ A;  5TDW A;  1WE9 A;  1E4U A;  1Z6U A;  5B75 A;  5C11 A;  3T6R A;  5G05 B;  2MD7 B;  5FEY A;  2ZET C;  2BAY A;  1WIM A;  4N4F A;  3PHD A;  2YQM A;  5C13 A;  2NAA A;  3N9M A;  4XI1 A;  2Y43 A;  1JOC A;  2YYR A;  2MD8 C;  2KWK A;  3SOX A;  5LCW B;  2F6J A;  2M85 A;  2PNX A;  4L7X A;  3KQI A;  4YC9 A;  2E6S A;  2EGP A;  1BOR A;  1WIL A;  5H1V A;  2MIQ A;  4UP5 A;  4WZ3 B;  2VJF B;  4Q6F A;  2RSD A;  5TBN A;  2ECV A;  2YHO A;  1HYI A;  3LQH A;  4I7B A;  1G25 A;  4AVX A;  1WEN A;  2LV9 A;  5G04 B;  3HTK C;  2K4D A;  1X4I A;  4S3O B;  2KIZ A;  3M62 A;  2VJF A;  2KWJ A;  5LKZ A;  5FER A;  3N9N A;  1VYX A;  1CHC A;  3KV5 A;  1MM2 A;  5H1U A;  2CSZ A;  2FSA A;  3O37 A;  3ZTG A;  2LGL A;  3LQJ A;  3C6W A;  2F42 A;  4UP0 A;  5DIN A;  5B76 A;  3ZPV 1;  4YAT A;  2K1J A;  1Z2Q A;  2ECT A;  2YRE A;  5AIU A;  5D1L B;  3U5M A;  2L43 A;  2VPG A;  3N9Q A;  2JRJ A;  4B86 C;  2CT2 A;  2YT5 A;  1IYM A;  3M99 A;  3L1X A;  3RTR B;  4AP4 A;  1FBV A;  3N9L A;  4L58 A;  4A4B A;  1HYJ A;  4R8P K;  3IHP A;  3ZYQ A;  2ECG A;  4YAX A;  5TRB A;  2LDR A;  4O64 A;  4GB0 A;  1XWH A;  5JG6 A;  3HCS A;  4FK5 A;  3SOW A;  4FIP A;  2MA6 A;  1ZBD B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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