The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
93
|
sequence length |
341
|
structure length |
341
|
Chain Sequence |
TSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFCVGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPLADHLLAPTRIYVKSVLELIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQWPEVFNWLQTAGNVEHHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIKASDSEQRVVIE
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
X-ray crystal structure of aminoimidazole ribonucleotide synthetase (PurM), from the Escherichia coli purine biosynthetic pathway at 2.5 A resolution.
pubmed doi rcsb |
| molecule tags |
Ligase
|
| source organism |
Escherichia coli
|
| molecule keywords |
PROTEIN (PHOSPHORIBOSYL-AMINOIMIDAZOLE SYNTHETASE)
|
| total genus |
93
|
| structure length |
341
|
| sequence length |
341
|
| chains with identical sequence |
B, C, D
|
| ec nomenclature |
ec
6.3.3.1: Phosphoribosylformylglycinamidine cyclo-ligase. |
| pdb deposition date | 1999-04-28 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00586 | AIRS | AIR synthase related protein, N-terminal domain |
| A | PF02769 | AIRS_C | AIR synthase related protein, C-terminal domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | 60s Ribosomal Protein L30; Chain: A; | PurM-like, N-terminal domain | ||
| Alpha Beta | Alpha-Beta Complex | Phosphoribosyl-aminoimidazole Synthetase; Chain A, domain 2 | PurM-like C-terminal domain |
#chains in the Genus database with same CATH superfamily 2Z01 A; 2HS0 A; 3WJQ A; 1VK3 A; 2HRU A; 3U0O A; 3VYT C; 3M84 A; 3WJR A; 2HS4 A; 2RB9 A; 2Z1T A; 2Z1F A; 3P4E A; 1CLI A; 3C9T A; 3VTI C; 3C9R A; 3MDO A; 2I6R A; 2ZOD A; 3FD5 A; 3QTY A; 3C9S A; 2HRY A; 3VYS C; 2ZAU A; 3D54 A; 3FD6 A; 3WJP A; 3VYU C; 5AVM A; 2Z1E A; 1VQV A; 2YYE A; 2V9Y A; 3C9U A; 3MCQ A; 3KIZ A; 2HS3 A; 2Z1U A; 2YXZ A; 2BTU A; 3VIU A; #chains in the Genus database with same CATH topology 4ZI7 B; 2PMP A; 4O2A B; 5HXZ A; 1VK3 A; 3ZP7 A; 3JAR A; 3DC2 A; 3N4Z A; 2P6Y A; 4TV8 A; 3M4S A; 3S03 A; 2HS4 A; 4TUY B; 3C9T A; 3RYC A; 3IKF A; 3CME F; 1Q82 H; 3E20 B; 5JCO A; 2CVL A; 1GO0 A; 1KNJ A; 4BVS A; 1DBF A; 4NQ3 A; 4G4X A; 3G71 F; 1GX1 A; 3KHN A; 2VAP A; 2OTL F; 2BTO A; 4O4J B; 3LWQ C; 1KQS F; 1GZ0 A; 2HP0 B; 1QVF F; 3CCR F; 1CK2 A; 2Z01 A; 2F9Z C; 5J2T B; 1TUB A; 3E1Y A; 1Z5W A; 5IT9 M; 4BT3 A; 1J7H A; 3IEW A; 3O85 A; 5HY0 A; 1W42 A; 3SIU A; 4BVQ A; 3N2K A; 5MN5 A; 3F6M A; 2Q1Y A; 2CSL A; 4X1I A; 5IJ0 B; 3NMU C; 3N2G B; 3FBA A; 1K73 H; 2QTP A; 1Q8R A; 4O4H A; 3UT5 B; 2WAL A; 1KD1 H; 2OZB A; 4TV9 A; 4LCK A; 4G88 A; 5KMG A; 1ODE A; 2VGN A; 3NK6 A; 1VQO F; 4X20 B; 2HS0 A; 2HX0 A; 3CYQ A; 3RYH B; 1W5E A; 3VO8 A; 1JD1 A; 1FFX A; 3I7T A; 1VQL F; 3WPX A; 3LFO A; 1UI9 A; 2H8C A; 1XBI A; 1JJ2 F; 2IG8 A; 3F0E A; 4I50 A; 2VAW A; 4IIJ A; 5BMV A; 3JAM M; 2MQE A; 4TV8 B; 1NJI H; 2Z1E A; 4I4T A; 3AGK A; 1DT9 A; 3P0Z A; 2CHS A; 5FNV A; 3RYC B; 2OHW A; 4BT2 A; 1IV1 A; 3JAS A; 4EI7 A; 5IJ9 B; 3P10 A; 3U0O A; 1W2B F; 2OTJ F; 3HAX D; 3IR9 A; 4X1K A; 4ZK7 A; 2CZW A; 3K0T A; 2NMU A; 3MDO A; 2HP0 A; 1COM A; 1X7O A; 5J2T A; 2QA4 F; 1TUB B; 4O4L A; 1IV2 A; 2RHJ A; 1VQ5 F; 3F0G A; 2CW4 A; 4FFB B; 3N2K B; 4X1I B; 1YJ9 F; 3CCM F; 4RQO A; 1OAP A; 1VQ7 F; 4O4H B; 3CCE F; 1JY8 A; 2N48 A; 2UYJ A; 4TV9 B; 5EIB C; 4YJ2 A; 5KMG B; 4ZHY B; 2I6R A; 3CCU F; 4X20 A; 3MBM A; 2JNB A; 5GIN C; 3CPW F; 3KJK A; 3HKB B; 2UYN A; 5EIB D; 3V7Q A; 3RYF A; 3S0W A; 1W5B A; 2V9Y A; 5C8Y A; 1FNJ A; 1YI2 F; 1IPA A; 4I50 B; 1R1M A; 3LWP C; 3BYQ A; 4IIJ B; 5HP8 A; 5CB4 A; 5BMV B; 2HRU A; 4C8E A; 3J80 M; 1KNK A; 3WJR A; 3P4E A; 4I4T B; 5JVD A; 1H48 A; 4C82 A; 1E7K A; 3HTN A; 5FNV B; 2ALE A; 1SDS A; 3NK7 A; 2FGY A; 3C9S A; 3JAS B; 4BT7 A; 3ESJ A; 1Q81 H; 4EI8 A; 1X7P A; 1M1K H; 5J2U A; 5IJ9 A; 3RA5 A; 5CA1 A; 2IQQ A; 4X1K B; 2L26 A; 2ZF8 A; 1VQV A; 2YYE A; 3JAT B; 3L7Q A; 4G4Z A; 4NWO B; 3C9U A; 5FLX M; 2YXZ A; 2AMT A; 5GAP K; 4BVT A; 3I55 F; 1ZWZ A; 3ELC A; 4O4L B; 2I6D A; 3S02 A; 3CXC F; 2QI2 A; 4B46 A; 3HKC A; 5LA6 A; 2RB9 A; 4FFB A; 3VTI C; 3RYI A; 4KWE A; 3HWU A; 3HKE B; 4RHA A; 4X3M A; 4EB6 A; 5B8F A; 1RA4 A; 5MN4 A; 3IEQ A; 4O2B A; 1YQN A; 2RHO A; 2QEX F; 3SIV A; 4DRX B; 3VI6 A; 2IAF A; 3B6N A; 5GAN K; 3CC2 F; 3MCQ A; 5LOV A; 4TZZ A; 4YJ2 B; 1U3P A; 2ZOV A; 5ITZ B; 5HWE A; 2EWC A; 4C8I A; 5LP6 A; 1X52 A; 1PF5 A; 1YIT F; 2H8E A; 3LDT A; 3HKB A; 2W8B C; 2UYN B; 3ERN A; 4X1Y A; 4YJ3 A; 2H6L A; 3RYF B; 4B45 A; 4LNU A; 5C8Y B; 1JFF A; 3FD5 A; 3QTY A; 4DXD A; 3CMA F; 3CCV F; 3K12 A; 3K14 A; 1W58 1; 3CB2 A; 3WGK A; 5CB4 B; 3FD6 A; 3CC7 F; 3VYU C; 4I55 B; 1Q86 H; 3M1X A; 1YHQ F; 3NVI B; 5JVD B; 4G4Y A; 1YGY A; 3ZO8 A; 3LYB A; 3D01 A; 5J2U B; 2GVI A; 3S0H A; 3WGL A; 4E6E A; 3V3T A; 1QU9 A; 5CA1 B; 3JAT A; 2AIZ P; 5JCO C; 4BW0 B; 4EI9 A; 1ONI A; 1W55 A; 3KE1 A; 3MQW A; 3VYS C; 2UYP A; 4X3L A; 2R75 1; 4C81 A; 4ZHQ A; 4G4V A; 3FPI A; 5EB0 A; 3QHD A; 3FFM A; 3HKC B; 5LA6 B; 1S72 F; 2G9I A; 3RYI B; 1UFY A; 1VQM F; 3HKE A; 5EAZ A; 4ZHW A; 4EB6 B; 1FNK A; 3IKE A; 1U43 A; 3CC4 F; 4O2B B; 2OTM A; 1H7M A; 3VYT C; 4DRX A; 1W3E X; 3E22 B; 1X25 A; 1M90 H; 5IYZ B; 1XHO A; 2DT4 A; 5LOV B; 4O4I B; 4U39 A; 1N8R H; 5ITZ A; 1IV4 A; 1VQN F; 5DCV A; 1W5F A; 5LP6 B; 5LXT A; 3WPW A; 3HJW C; 1TVK B; 2KGW A; 4ERH A; 2KTV A; 4YJ3 B; 3V4D A; 4X1Y B; 4LNU B; 3KIZ A; 1RLG A; 5GIP C; 2RHH A; 4G4W A; 1JFF B; 1OFU A; 2ZVY A; 5LP6 C; 3WJQ A; 4B5C A; 3KJJ A; 5JH7 B; 3HKD A; 1W41 A; 3DDN A; 4ZOL B; 5EYP B; 4I55 A; 1IV3 A; 3CCQ F; 3CCS F; 3JAK A; 4WBN B; 3TD5 A; 2HQS C; 3OW2 F; 3K2X A; 2RHL A; 5G4U C; 3VOB A; 3TD3 A; 3PLA C; 1Z5V A; 2GZL A; 5FJ4 C; 3F0D A; 1QD9 A; 1XV2 A; 2R6R 1; 1VHA A; 2KG4 A; 2BTU A; 3VMF B; 3N4Y A; 1VQ4 F; 2K1S A; 4U3J B; 3WXM B; 3VCZ A; 3EOR A; 4ZHQ B; 3QUW A; 3JAW B; 1SZQ A; 1RQ7 A; 3TD4 A; 3CYP B; 2HRY A; 2UZH A; 4F6R A; 4NUT A; 4BT6 A; 1QVG F; 1RLU A; 2UYK A; 3ZP4 A; 2CWJ A; 3E22 A; 2LBT A; 4HNA B; 3G6E F; 5IYZ A; 1YJN F; 3ON1 A; 3RE3 A; 3WGN A; 3VIU A; 3S0Y A; 3ZOP A; 4O4I A; 3WGJ A; 3S06 A; 5GON B; 3CPQ A; 5HP7 A; 5EZY A; 5LXT B; 5HY4 A; 1TVK A; 2Z1T A; 1QAH A; 3JAL B; 3I56 F; 1T0K B; 1VH8 A; 1W40 A; 2Q1X A; 3R0P A; 3MCA B; 2ZOD A; 4XCQ A; 3RA6 A; 3CG6 A; 5G4V C; 4BT5 A; 5JH7 A; 5KX5 A; 1Q7Y H; 3D54 A; 3WJP A; 3HKD B; 1H47 A; 4R40 B; 4ZOL A; 4PWT A; 1JN1 A; 5EYP A; 1SA0 A; 5AVM A; 2LBW A; 2CHT A; 5HY2 A; 2BTQ B; 2HS3 A; 2GLZ A; 3JAK B; 1W5A A; 3WGM A; 5LYJ A; 1K9M H; 4WBN A; 2LCA A; 5GIO C; 4IHJ A; 3I3F A; 5CA0 A; 3GHZ A; 5JQG B; 2KTU A; 1RQ2 A; 1VQ6 F; 1GO1 A; 1YIJ F; 3IMP A; 1CLI A; 3F0F A; 3C9R A; 5MN6 A; 4ZI7 A; 1FSZ A; 4O2A A; 5EO3 A; 2PHN A; 3Q8H A; 3GYQ A; 3JAR B; 4BVR A; 1KC8 H; 1VQ8 F; 2ZAU A; 2ZVZ A; 4U3J A; 2HVY D; 5HY1 A; 2VXY A; 3T80 A; 3OBW A; 4TUY A; 3JCM M; 3LWR C; 3JAW A; 2Z1U A; 4M8I A; 5EB1 B; 2LBX A; 3CD6 F; 4F6R B; 1W57 A; 1T0A A; 1NQ3 A; 3M84 A; 4O4J A; 3PAF A; 4C4W C; 2Z1F A; 4BT4 A; 1CN7 A; 4HNA A; 3LWV C; 2B33 A; 2BO1 A; 2VAM A; 3D00 A; 3J7A R; 3VOA A; 5A2Q M; 2DYY A; 5GON A; 1U40 A; 3CCJ F; 5EZY B; 3J81 M; 4B62 A; 3CCL F; 2VGM A; 5HXU A; 1NMU B; 3JAL A; 2HP3 A; 3GTZ A; 5IJ0 A; 3N2G A; 4ZHV A; 1VQ9 F; 3C8L A; 3UT5 A; 3G4S F; 1W59 A; 3OON A; 1PXW A; 5KX5 B; 5EWR A; 1K8A H; 1XRG A; 3NVK E; 1SA0 B; 3LME A; 5LYJ B; 2AIF A; 4C8G A; 3RYH A; 1YJW F; 4IHJ B; 1FFX B; 1U3L A; 5CA0 B; 5JQG A; 3V7E A; 3OBY A; 1VQP F; 2FC3 A; 3JVH A; 3LWO C; 1VQK F; 4BY9 D; #chains in the Genus database with same CATH homology 2Z01 A; 2HS0 A; 3WJQ A; 1VK3 A; 2HRU A; 3U0O A; 3VYT C; 3M84 A; 3WJR A; 2HS4 A; 2RB9 A; 2Z1T A; 2Z1F A; 3P4E A; 1CLI A; 3C9T A; 3VTI C; 3C9R A; 3MDO A; 2I6R A; 2ZOD A; 3FD5 A; 3QTY A; 3C9S A; 2HRY A; 3VYS C; 2ZAU A; 3D54 A; 3FD6 A; 3WJP A; 3VYU C; 5AVM A; 2Z1E A; 1VQV A; 2YYE A; 2V9Y A; 3C9U A; 3MCQ A; 3KIZ A; 2HS3 A; 2Z1U A; 2YXZ A; 2BTU A; 3VIU A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
