4BT2A

Acetolactate decarboxylase with a bound 1,2-ethanediol
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
237
structure length
237
Chain Sequence
APKNVLFQYSTINALMLGQFEGDLTLKDLKLRGDMGLGTINDLDGEMIQMGTKFYQIDSTGKLSELPESVKTPFAVTTHFEPKEKTTLTNVQDYNQLTKMLEEKFENKNVFYAVKLTGTFKMVKARTVPKQTRPYPQLTEVTKKQSEFEFKNVKGTLIGFYTPNYAAALNVPGFHLHFITEDKTSGGHVLNLQFDNANLEISPIHEFDVQLPHTDDFAHSDLTQVTTSQVHQAESER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ALPHA-ACETOLACTATE DECARBOXYLASE
publication title Structure and Mechanism of Acetolactate Decarboxylase
pubmed doi rcsb
source organism Brevibacillus brevis
molecule tags Lyase
total genus 74
structure length 237
sequence length 237
ec nomenclature ec 4.1.1.5: Acetolactate decarboxylase.
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03306 AAL_decarboxy Alpha-acetolactate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1330.80 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 4bt2A02
3.30.1330.80 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 4bt2A01
4BT4A 2NMUA 3HTNA 2HX0A 2H6LA 2P6YA 1XV2A 4BT5A 2DT4A 4BT2A 3HWUA 4BT6A 4BT3A 4BT7A
chains in the Genus database with same CATH superfamily
3V4DA 1VQLF 1XV2A 3WGKA 3RYHA 1NJIH 4O4HB 5EZYB 2V9YA 4IIJA 2GVIA 4R40B 1Q81H 2FC3A 3ZOPA 3RYCA 1TVKA 1YIJF 5DCVA 2HRYA 3JASB 1XBIA 2K1SA 2H8CA 5J2TA 5KMGB 1K73H 4YJ3A 5LA6B 4I55B 1SA0B 3I3FA 3F0DA 3LMEA 2FGYA 2KGWA 3G4SF 3CCVF 2YYEA 3NK7A 4TV9B 3VI6A 4BT5A 2QA4F 3WGMA 4BT7A 3F6MA 1YHQF 4O2BB 3OBYA 3VYSC 2VGNA 2I6DA 2VAMA 4U3JB 4O4IA 1W581 1VQMF 4TV8A 5JQGB 2DYYA 2UZHA 1VQ5F 4YJ2B 4BT4A 4G88A 2IAFA 3G71F 3JAKA 3OONA 4ZOLB 1Q86H 1JFFA 3O85A 3J80M 4E6EA 3FBAA 4C81A 4BT6A 2Z1EA 5J2UA 4C4WC 2ZODA 3CCJF 1E7KA 2Z1TA 4BT2A 1KD1H 3K12A 3I7TA 4NUTA 3CCEF 1QD9A 2ZVZA 4G4ZA 3WPXA 2ZOVA 3K14A 2I6RA 2WALA 3IKFA 5HY0A 3VMFB 3KJJA 5IJ0A 4X20A 4BVQA 1CK2A 3WGJA 3HKCB 3VIUA 4IHJB 1N8RH 2QEXF 2W8BC 5LP6C 3E20B 2RB9A 2DT4A 2CHSA 3KIZA 2RHJA 3VCZA 2UYPA 3SIUA 3MDOA 3LWRC 2VGMA 1QAHA 3IEWA 1VQVA 4X1KA 3CB2A 3JARA 1KC8H 3VYUC 3FFMA 1R1MA 3ZO8A 3LWOC 2P6YA 3CYQA 3V7EA 1GO0A 3E22B 4B45A 3DC2A 2OTJF 2CZWA 4NWOB 3IR9A 2OHWA 5EYPB 1W5FA 4I50A 4X1IA 1K9MH 4LCKA 2VAPA 3GTZA 3ERNA 1X25A 3HKDA 2ZVYA 3LWQC 1Q7YH 3QTYA 3CCSF 5EWRA 4LNUA 5HXUA 4X1YA 2Z1FA 1UI9A 1TVKB 3RYCB 3MQWA 4F6RA 3RA5A 3JAWB 3K2XA 2GLZA 3L7QA 1W2BF 3CCMF 1H48A 3V7QA 3C9RA 1KNJA 4O4LA 3S0HA 2F9ZC 2PHNA 5CB4A 3KE1A 3JVHA 5CA1B 4BW0B 2BTUA 5B8FA 3N2GA 3C9UA 3FPIA 1NQ3A 1M1KH 3P0ZA 1FFXA 1QVFF 1OFUA 3IMPA 1OAPA 1SZQA 2HX0A 4TV8B 3JATA 5MN6A 3S06A 5IYZB 3V3TA 4EB6A 5G4UC 5HP7A 3HKEB 1DBFA 3JAKB 3NMUC 3RYFA 5GIOC 4ZHQB 5C8YA 2GZLA 3D01A 1DT9A 4ZI7A 1VQNF 2VXYA 1FNJA 3P4EA 5FNVA 4G4VA 3S0YA 1W5BA 1RLUA 1NMUB 4G4YA 3U0OA 5LOVA 2CVLA 3GYQA 4X20B 3MCQA 4G4WA 3RYIB 1VQOF 1JY8A 1IV3A 3ELCA 1Z5VA 5BMVA 5CA0B 5ITZB 4RQOA 4WBNB 2Z1UA 4O4JA 5IJ9B 1ZWZA 5LP6B 2H6LA 4C8GA 3CCUF 3TD5A 5LXTA 5MN5A 2HP0A 5HY2A 2G9IA 2VAWA 3CPWF 1Q82H 1X7PA 3CCRF 3NVIB 3VO8A 1JN1A 1VQ4F 3QUWA 2LBTA 4I50B 4X1IB 1VH8A 2BO1A 2L26A 1ONIA 4O2AB 5AVMA 4X1YB 4TUYB 3HJWC 1S72F 2YXZA 4BT3A 4DRXA 1CLIA 1IPAA 1T0KB 4B46A 1VQ7F 1M90H 3NK6A 1JD1A 2CW4A 4FFBA 2UYKA 5GONA 4O4LB 3CCLF 3LWPC 2LBWA 2HS4A 4I4TB 5EO3A 5LYJA 3OBWA 1FFXB 4I55A 1SA0A 3LFOA 3IKEA 1IV4A 3KJKA 3FD6A 2JNBA 1YQNA 1W42A 2CSLA 4U39A 4EB6B 1H47A 1VQ9F 4O2BA 3CD6F 3M84A 3RYHB 4IIJB 3RYFB 5EB0A 5EIBD 2KTUA 3CG6A 5JQGA 3J7AR 4ZI7B 3F0EA 1YITF 3PLAC 5FNVB 3G6EF 3HTNA 5HY4A 5J2TB 1W5EA 5HWEA 3HKBA 3VOBA 3C9SA 4YJ3B 1YGYA 3QHDA 4X3LA 5FJ4C 5EAZA 3JCMM 3WGNA 5MN4A 3N2KA 1XRGA 2HS3A 2B33A 1K8AH 4O4IB 4RHAA 4ZHVA 3S02A 1FSZA 1Z5WA 3E1YA 4O4JB 2HS0A 4PWTA 2NMUA 3T80A 2HVYD 5KX5A 3HKCA 3OW2F 2RHHA 5GANK 5LXTB 1H7MA 1J7HA 1JFFB 3LWVC 5J2UB 3CPQA 4KWEA 1U43A 2Q1XA 3CYPB 1W59A 1RQ2A 3B6NA 1JJ2F 2OZBA 3VTIC 4X3MA 3BYQA 2BTQB 5HP8A 5JH7A 2ZAUA 2ALEA 4DRXB 1Q8RA 5IJ0B 2RHLA 1YJNF 3WXMB 5EYPA 3CC2F 1TUBA 3CCQF 1W5AA 2CHTA 2MQEA 4FFBB 4EI9A 5GONB 3UT5A 3CXCF 3WJRA 2IQQA 3DDNA 3JAWA 1W3EX 5LYJB 1KQSF 3JALA 5GINC 5JVDA 4BVTA 1U40A 3C8LA 4X1KB 2UYNA 3JARB 3M1XA 5GAPK 2OTLF 3IEQA 1COMA 3VYTC 4EI8A 3LYBA 1VQPF 2R751 3CC7F 1RA4A 5CA1A 4C8IA 4XCQA 1XHOA 1YJWF 1RQ7A 5GIPC 3TD4A 1U3PA 4HNAA 1YI2F 5IT9M 2LCAA 1PF5A 3HKDB 3RE3A 4LNUB 3MCAB 3WPWA 1W40A 1FNKA 2QI2A 2RHOA 5IYZA 3Q8HA 2QTPA 4F6RB 4WBNA 3HKEA 3HKBB 4TZZA 4O4HA 2HRUA 1VQ6F 5EZYA 4M8IA 3M4SA 2IG8A 4ZHQA 1SDSA 3N4YA 4B5CA 1GX1A 1VQ8F 2N48A 5CB4B 3JASA 3N2KB 3NVKE 3SIVA 3N2GB 2AMTA 1QU9A 5KMGA 5LA6A 5JCOC 3VOAA 3ESJA 3D54A 2KG4A 5EB1B 2UYJA 4ZK7A 4C8EA 4TV9A 1W55A 3JATB 3N4ZA 3WGLA 2PMPA 3RYIA 5KX5B 5JCOA 1RLGA 4U3JA 2EWCA 5CA0A 5ITZA 3WJPA 3FD5A 1UFYA 3CC4F 5C8YB 5G4VC 4C82A 1GO1A 1IV1A 5IJ9A 3PAFA 5LP6A 4YJ2A 2AIZP 4ZHYB 2H8EA 2KTVA 1GZ0A 3KHNA 2CWJA 3C9TA 4ZOLA 5EIBC 3P10A 3S0WA 5JH7B 4BY9D 1X7OA 2R6R1 3GHZA 4EI7A 1QVGF 5LOVB 2Z01A 3TD3A 3D00A 3F0GA 4DXDA 2AIFA 3LDTA 4ERHA 3ZP4A 5HXZA 1W57A 1TUBB 1ODEA 4O2AA 5A2QM 1CN7A 5BMVB 1PXWA 3CMEF 3UT5B 1KNKA 5HY1A 2HQSC 3EORA 4TUYA 4G4XA 3F0FA 2HP3A 2ZF8A 2LBXA 3RA6A 2OTMA 3JALB 3J81M 5JVDB 2UYNB 4IHJA 5FLXM 3I55F 4B62A 3ZP7A 2BTOA 1W41A 3MBMA 1VQKF 2HP0B 3S03A 3K0TA 4ZHWA 1X52A 3HWUA 3CMAF 4BVRA 4I4TA 3HAXD 1U3LA 3JAMM 1VHAA 4HNAB 1T0AA 1IV2A 4BVSA 3R0PA 4NQ3A 1VK3A 3WJQA 3AGKA 1YJ9F 3ON1A 3I56F 3E22A 2Q1YA
chains in the Genus database with same CATH topology
4BT4A 2NMUA 3HTNA 2HX0A 2H6LA 2P6YA 1XV2A 4BT5A 2DT4A 4BT2A 3HWUA 4BT6A 4BT3A 4BT7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BT4 A;  2NMU A;  3HTN A;  2HX0 A;  2H6L A;  2P6Y A;  1XV2 A;  4BT5 A;  2DT4 A;  4BT2 A;  3HWU A;  4BT6 A;  4BT3 A;  4BT7 A; 
#chains in the Genus database with same CATH topology
 3V4D A;  1VQL F;  1XV2 A;  3WGK A;  3RYH A;  1NJI H;  4O4H B;  5EZY B;  2V9Y A;  4IIJ A;  2GVI A;  4R40 B;  1Q81 H;  2FC3 A;  3ZOP A;  3RYC A;  1TVK A;  1YIJ F;  5DCV A;  2HRY A;  3JAS B;  1XBI A;  2K1S A;  2H8C A;  5J2T A;  5KMG B;  1K73 H;  4YJ3 A;  5LA6 B;  4I55 B;  1SA0 B;  3I3F A;  3F0D A;  3LME A;  2FGY A;  2KGW A;  3G4S F;  3CCV F;  2YYE A;  3NK7 A;  4TV9 B;  3VI6 A;  4BT5 A;  2QA4 F;  3WGM A;  4BT7 A;  3F6M A;  1YHQ F;  4O2B B;  3OBY A;  3VYS C;  2VGN A;  2I6D A;  2VAM A;  4U3J B;  4O4I A;  1W58 1;  1VQM F;  4TV8 A;  5JQG B;  2DYY A;  2UZH A;  1VQ5 F;  4YJ2 B;  4BT4 A;  4G88 A;  2IAF A;  3G71 F;  3JAK A;  3OON A;  4ZOL B;  1Q86 H;  1JFF A;  3O85 A;  3J80 M;  4E6E A;  3FBA A;  4C81 A;  4BT6 A;  2Z1E A;  5J2U A;  4C4W C;  2ZOD A;  3CCJ F;  1E7K A;  2Z1T A;  4BT2 A;  1KD1 H;  3K12 A;  3I7T A;  4NUT A;  3CCE F;  1QD9 A;  2ZVZ A;  4G4Z A;  3WPX A;  2ZOV A;  3K14 A;  2I6R A;  2WAL A;  3IKF A;  5HY0 A;  3VMF B;  3KJJ A;  5IJ0 A;  4X20 A;  4BVQ A;  1CK2 A;  3WGJ A;  3HKC B;  3VIU A;  4IHJ B;  1N8R H;  2QEX F;  2W8B C;  5LP6 C;  3E20 B;  2RB9 A;  2DT4 A;  2CHS A;  3KIZ A;  2RHJ A;  3VCZ A;  2UYP A;  3SIU A;  3MDO A;  3LWR C;  2VGM A;  1QAH A;  3IEW A;  1VQV A;  4X1K A;  3CB2 A;  3JAR A;  1KC8 H;  3VYU C;  3FFM A;  1R1M A;  3ZO8 A;  3LWO C;  2P6Y A;  3CYQ A;  3V7E A;  1GO0 A;  3E22 B;  4B45 A;  3DC2 A;  2OTJ F;  2CZW A;  4NWO B;  3IR9 A;  2OHW A;  5EYP B;  1W5F A;  4I50 A;  4X1I A;  1K9M H;  4LCK A;  2VAP A;  3GTZ A;  3ERN A;  1X25 A;  3HKD A;  2ZVY A;  3LWQ C;  1Q7Y H;  3QTY A;  3CCS F;  5EWR A;  4LNU A;  5HXU A;  4X1Y A;  2Z1F A;  1UI9 A;  1TVK B;  3RYC B;  3MQW A;  4F6R A;  3RA5 A;  3JAW B;  3K2X A;  2GLZ A;  3L7Q A;  1W2B F;  3CCM F;  1H48 A;  3V7Q A;  3C9R A;  1KNJ A;  4O4L A;  3S0H A;  2F9Z C;  2PHN A;  5CB4 A;  3KE1 A;  3JVH A;  5CA1 B;  4BW0 B;  2BTU A;  5B8F A;  3N2G A;  3C9U A;  3FPI A;  1NQ3 A;  1M1K H;  3P0Z A;  1FFX A;  1QVF F;  1OFU A;  3IMP A;  1OAP A;  1SZQ A;  2HX0 A;  4TV8 B;  3JAT A;  5MN6 A;  3S06 A;  5IYZ B;  3V3T A;  4EB6 A;  5G4U C;  5HP7 A;  3HKE B;  1DBF A;  3JAK B;  3NMU C;  3RYF A;  5GIO C;  4ZHQ B;  5C8Y A;  2GZL A;  3D01 A;  1DT9 A;  4ZI7 A;  1VQN F;  2VXY A;  1FNJ A;  3P4E A;  5FNV A;  4G4V A;  3S0Y A;  1W5B A;  1RLU A;  1NMU B;  4G4Y A;  3U0O A;  5LOV A;  2CVL A;  3GYQ A;  4X20 B;  3MCQ A;  4G4W A;  3RYI B;  1VQO F;  1JY8 A;  1IV3 A;  3ELC A;  1Z5V A;  5BMV A;  5CA0 B;  5ITZ B;  4RQO A;  4WBN B;  2Z1U A;  4O4J A;  5IJ9 B;  1ZWZ A;  5LP6 B;  2H6L A;  4C8G A;  3CCU F;  3TD5 A;  5LXT A;  5MN5 A;  2HP0 A;  5HY2 A;  2G9I A;  2VAW A;  3CPW F;  1Q82 H;  1X7P A;  3CCR F;  3NVI B;  3VO8 A;  1JN1 A;  1VQ4 F;  3QUW A;  2LBT A;  4I50 B;  4X1I B;  1VH8 A;  2BO1 A;  2L26 A;  1ONI A;  4O2A B;  5AVM A;  4X1Y B;  4TUY B;  3HJW C;  1S72 F;  2YXZ A;  4BT3 A;  4DRX A;  1CLI A;  1IPA A;  1T0K B;  4B46 A;  1VQ7 F;  1M90 H;  3NK6 A;  1JD1 A;  2CW4 A;  4FFB A;  2UYK A;  5GON A;  4O4L B;  3CCL F;  3LWP C;  2LBW A;  2HS4 A;  4I4T B;  5EO3 A;  5LYJ A;  3OBW A;  1FFX B;  4I55 A;  1SA0 A;  3LFO A;  3IKE A;  1IV4 A;  3KJK A;  3FD6 A;  2JNB A;  1YQN A;  1W42 A;  2CSL A;  4U39 A;  4EB6 B;  1H47 A;  1VQ9 F;  4O2B A;  3CD6 F;  3M84 A;  3RYH B;  4IIJ B;  3RYF B;  5EB0 A;  5EIB D;  2KTU A;  3CG6 A;  5JQG A;  3J7A R;  4ZI7 B;  3F0E A;  1YIT F;  3PLA C;  5FNV B;  3G6E F;  3HTN A;  5HY4 A;  5J2T B;  1W5E A;  5HWE A;  3HKB A;  3VOB A;  3C9S A;  4YJ3 B;  1YGY A;  3QHD A;  4X3L A;  5FJ4 C;  5EAZ A;  3JCM M;  3WGN A;  5MN4 A;  3N2K A;  1XRG A;  2HS3 A;  2B33 A;  1K8A H;  4O4I B;  4RHA A;  4ZHV A;  3S02 A;  1FSZ A;  1Z5W A;  3E1Y A;  4O4J B;  2HS0 A;  4PWT A;  2NMU A;  3T80 A;  2HVY D;  5KX5 A;  3HKC A;  3OW2 F;  2RHH A;  5GAN K;  5LXT B;  1H7M A;  1J7H A;  1JFF B;  3LWV C;  5J2U B;  3CPQ A;  4KWE A;  1U43 A;  2Q1X A;  3CYP B;  1W59 A;  1RQ2 A;  3B6N A;  1JJ2 F;  2OZB A;  3VTI C;  4X3M A;  3BYQ A;  2BTQ B;  5HP8 A;  5JH7 A;  2ZAU A;  2ALE A;  4DRX B;  1Q8R A;  5IJ0 B;  2RHL A;  1YJN F;  3WXM B;  5EYP A;  3CC2 F;  1TUB A;  3CCQ F;  1W5A A;  2CHT A;  2MQE A;  4FFB B;  4EI9 A;  5GON B;  3UT5 A;  3CXC F;  3WJR A;  2IQQ A;  3DDN A;  3JAW A;  1W3E X;  5LYJ B;  1KQS F;  3JAL A;  5GIN C;  5JVD A;  4BVT A;  1U40 A;  3C8L A;  4X1K B;  2UYN A;  3JAR B;  3M1X A;  5GAP K;  2OTL F;  3IEQ A;  1COM A;  3VYT C;  4EI8 A;  3LYB A;  1VQP F;  2R75 1;  3CC7 F;  1RA4 A;  5CA1 A;  4C8I A;  4XCQ A;  1XHO A;  1YJW F;  1RQ7 A;  5GIP C;  3TD4 A;  1U3P A;  4HNA A;  1YI2 F;  5IT9 M;  2LCA A;  1PF5 A;  3HKD B;  3RE3 A;  4LNU B;  3MCA B;  3WPW A;  1W40 A;  1FNK A;  2QI2 A;  2RHO A;  5IYZ A;  3Q8H A;  2QTP A;  4F6R B;  4WBN A;  3HKE A;  3HKB B;  4TZZ A;  4O4H A;  2HRU A;  1VQ6 F;  5EZY A;  4M8I A;  3M4S A;  2IG8 A;  4ZHQ A;  1SDS A;  3N4Y A;  4B5C A;  1GX1 A;  1VQ8 F;  2N48 A;  5CB4 B;  3JAS A;  3N2K B;  3NVK E;  3SIV A;  3N2G B;  2AMT A;  1QU9 A;  5KMG A;  5LA6 A;  5JCO C;  3VOA A;  3ESJ A;  3D54 A;  2KG4 A;  5EB1 B;  2UYJ A;  4ZK7 A;  4C8E A;  4TV9 A;  1W55 A;  3JAT B;  3N4Z A;  3WGL A;  2PMP A;  3RYI A;  5KX5 B;  5JCO A;  1RLG A;  4U3J A;  2EWC A;  5CA0 A;  5ITZ A;  3WJP A;  3FD5 A;  1UFY A;  3CC4 F;  5C8Y B;  5G4V C;  4C82 A;  1GO1 A;  1IV1 A;  5IJ9 A;  3PAF A;  5LP6 A;  4YJ2 A;  2AIZ P;  4ZHY B;  2H8E A;  2KTV A;  1GZ0 A;  3KHN A;  2CWJ A;  3C9T A;  4ZOL A;  5EIB C;  3P10 A;  3S0W A;  5JH7 B;  4BY9 D;  1X7O A;  2R6R 1;  3GHZ A;  4EI7 A;  1QVG F;  5LOV B;  2Z01 A;  3TD3 A;  3D00 A;  3F0G A;  4DXD A;  2AIF A;  3LDT A;  4ERH A;  3ZP4 A;  5HXZ A;  1W57 A;  1TUB B;  1ODE A;  4O2A A;  5A2Q M;  1CN7 A;  5BMV B;  1PXW A;  3CME F;  3UT5 B;  1KNK A;  5HY1 A;  2HQS C;  3EOR A;  4TUY A;  4G4X A;  3F0F A;  2HP3 A;  2ZF8 A;  2LBX A;  3RA6 A;  2OTM A;  3JAL B;  3J81 M;  5JVD B;  2UYN B;  4IHJ A;  5FLX M;  3I55 F;  4B62 A;  3ZP7 A;  2BTO A;  1W41 A;  3MBM A;  1VQK F;  2HP0 B;  3S03 A;  3K0T A;  4ZHW A;  1X52 A;  3HWU A;  3CMA F;  4BVR A;  4I4T A;  3HAX D;  1U3L A;  3JAM M;  1VHA A;  4HNA B;  1T0A A;  1IV2 A;  4BVS A;  3R0P A;  4NQ3 A;  1VK3 A;  3WJQ A;  3AGK A;  1YJ9 F;  3ON1 A;  3I56 F;  3E22 A;  2Q1Y A; 
#chains in the Genus database with same CATH homology
 4BT4 A;  2NMU A;  3HTN A;  2HX0 A;  2H6L A;  2P6Y A;  1XV2 A;  4BT5 A;  2DT4 A;  4BT2 A;  3HWU A;  4BT6 A;  4BT3 A;  4BT7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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