4BT2A

Acetolactate decarboxylase with a bound 1,2-ethanediol
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
237
structure length
237
Chain Sequence
b'APKNVLFQYSTINALMLGQFEGDLTLKDLKLRGDMGLGTINDLDGEMIQMGTKFYQIDSTGKLSELPESVKTPFAVTTHFEPKEKTTLTNVQDYNQLTKMLEEKFENKNVFYAVKLTGTFKMVKARTVPKQTRPYPQLTEVTKKQSEFEFKNVKGTLIGFYTPNYAAALNVPGFHLHFITEDKTSGGHVLNLQFDNANLEISPIHEFDVQLPHTDDFAHSDLTQVTTSQVHQAESER'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ALPHA-ACETOLACTATE DECARBOXYLASE
publication title Structure and Mechanism of Acetolactate Decarboxylase
pubmed doi rcsb
source organism Brevibacillus brevis
molecule tags Lyase
total genus 74
structure length 237
sequence length 237
ec nomenclature ec 4.1.1.5: Acetolactate decarboxylase.
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03306 AAL_decarboxy Alpha-acetolactate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1330.80 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 4bt2A02
3.30.1330.80 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 4bt2A01
2HX0A 2DT4A 4BT7A 4BT3A 4BT2A 2H6LA 1XV2A 2P6YA 4BT6A 3HWUA 3HTNA 4BT4A 2NMUA 4BT5A
chains in the Genus database with same CATH superfamily
2CW4A 2F9ZC 5HY0A 4BT6A 2QEXF 5EWRA 1M90H 1OFUA 3VTIC 1YI2F 1FNJA 2BO1A 3VYTC 3S0HA 1X25A 5C8YA 3CD6F 3WPWA 1JFFA 3R0PA 1VQMF 4C8GA 4ZHWA 1U3LA 1ONIA 3LWQC 1VQNF 2HRYA 3CYPB 3J80M 2K1SA 2OHWA 3RYCA 1U3PA 2UYNA 4ZOLA 5EB1B 3TD4A 5J2TB 3C9RA 1RQ7A 4X20A 3CPWF 5GONA 5JCOC 1QD9A 1RQ2A 2Z1UA 2AIZP 4FFBA 5LXTB 2AIFA 4RQOA 4B62A 3JATB 3JALB 4TV9A 5LOVB 1KNJA 3S0YA 5G4UC 2HS3A 3FPIA 3ELCA 3JARA 4O4HA 5LYJA 2VAMA 2I6RA 3S06A 4C4WC 2VAWA 3SIVA 1VH8A 2IAFA 2ZODA 4O4JA 1GZ0A 4O2AA 1VQ9F 1GO1A 1JY8A 3VOAA 3QUWA 5AVMA 3HAXD 5IJ9A 2L26A 1N8RH 3MCQA 3IMPA 4EB6A 3RYHA 2OZBA 2VGNA 3NVIB 3ZP7A 3K2XA 4BT4A 3TD5A 3FFMA 3N2KA 4G4ZA 2CWJA 5IJ0A 2CHSA 3KIZA 5J2UB 4BY9D 2KG4A 1SA0B 3UT5B 3HTNA 3U0OA 3N2GB 3RYFA 3CCJF 3HKBB 5EAZA 3G6EF 3B6NA 4I50B 1H7MA 3F0EA 1W59A 2W8BC 1RLUA 4TUYA 1UI9A 4YJ2B 2BTUA 2GVIA 3NK6A 3RA6A 5IT9M 2MQEA 1QVFF 1YJNF 4ZHQA 4I4TA 4M8IA 4LNUA 4O2BB 2LBTA 1FFXB 2ZAUA 4O4LB 1VQOF 4IHJA 4BVRA 2EWCA 3GTZA 5JQGB 1U43A 3JASA 5EYPA 5MN4A 5KMGA 3CCEF 1R1MA 1JJ2F 2OTJF 1JN1A 1QVGF 3D00A 1E7KA 1CK2A 2IQQA 2VGMA 3OBYA 3FD5A 1W55A 4YJ3B 2LBWA 5FJ4C 3P10A 3BYQA 3RYIA 5HY4A 4E6EA 2H8CA 1CLIA 1W5AA 3MDOA 2ZVZA 4C8EA 4B45A 2HRUA 1K8AH 1VQ6F 3VYUC 3JAKA 1VQLF 4HNAA 3HKCB 2RHHA 3G4SF 1OAPA 2HP0B 5CA0B 4R40B 3GHZA 4X1KA 4WBNA 5GIPC 2UZHA 1VQ8F 3WPXA 4X1IB 3IKEA 1W40A 3LWRC 4G4XA 1VQ4F 4G4VA 1PXWA 2RB9A 3L7QA 2LCAA 4C82A 2QI2A 5JVDB 4I55B 1Q8RA 5IYZA 5EZYB 5GIOC 3JAMM 4X1YA 5HXUA 3F6MA 5HY1A 2KTVA 4U3JA 3HKEA 3IKFA 3VOBA 1VQPF 3LWPC 5FNVB 1COMA 4DRXA 3JAWB 3NK7A 3CXCF 3I3FA 1RA4A 3CPQA 3IR9A 5LA6B 1IV3A 3OW2F 4B46A 1U40A 2KTUA 4X3LA 1NMUB 5CB4B 3CYQA 3S02A 3D01A 3V3TA 4C81A 3F0GA 1CN7A 5MN5A 1X7PA 2UYKA 3AGKA 3DC2A 3K14A 1TVKB 2LBXA 2Q1XA 2UYJA 1W2BF 4ZI7B 3CCRF 3NMUC 5EO3A 3P0ZA 3S0WA 3S03A 3V7QA 5MN6A 5J2TA 1RLGA 2VAPA 3HWUA 3C8LA 3CB2A 4IIJB 5LXTA 5JH7B 3JATA 3JALA 5LOVA 2V9YA 4G4YA 5LP6C 3MCAB 1X52A 3NVKE 5A2QM 2BTQB 3WJQA 3CC2F 1SDSA 1J7HA 2Z1TA 1S72F 3N4YA 3ON1A 4BVQA 4DXDA 3WGJA 3QTYA 5CA1B 3J81M 1QAHA 1VQ5F 5ITZB 2UYPA 1VK3A 2N48A 3K0TA 3HKDB 4BVTA 1SZQA 3CCMF 2Z01A 1Z5VA 3F0DA 2HVYD 4BT2A 2H6LA 2JNBA 1VQVA 3KJJA 1VQ7F 4BW0B 5J2UA 4X3MA 1SA0A 2HS0A 3UT5A 3N2GA 4F6RB 3HKBA 3I56F 4I50A 1W57A 2ZF8A 3OONA 1PF5A 2GZLA 3V4DA 1Z5WA 2I6DA 3ZO8A 4LCKA 1W5FA 3KE1A 4TV8B 1T0AA 3ERNA 1YJ9F 2IG8A 4YJ2A 1XBIA 3GYQA 1VHAA 1Q81H 3K12A 5BMVB 3RE3A 1X7OA 2ZVYA 4O2BA 1FFXA 4O4LA 4PWTA 4ERHA 5GAPK 5JQGA 5LP6B 2FGYA 4BT3A 2P6YA 1K9MH 1QU9A 1XRGA 2HP3A 3EORA 3M1XA 3WGNA 5DCVA 1UFYA 3CCLF 3FD6A 1NJIH 4YJ3A 5HP7A 4ZK7A 3CCUF 2B33A 4EI7A 3JCMM 4O4IB 3E22B 3LWOC 3WJPA 3WGKA 2H8EA 1DT9A 3HKCA 1W5BA 1NQ3A 1TUBB 2HP0A 5KX5B 5CA0A 2VXYA 2PHNA 1XV2A 3KJKA 2Z1FA 3I55F 4X1IA 1YITF 3VI6A 2CVLA 2CSLA 1KD1H 3E1YA 4TZZA 2RHLA 4BT5A 1ZWZA 3CC4F 2QTPA 3O85A 5JVDA 4I55A 3ESJA 3I7TA 5EZYA 3P4EA 1Q82H 1W5EA 1H48A 5C8YB 2YYEA 1JFFB 3CG6A 2Z1EA 4BVSA 1JD1A 1KC8H 5FNVA 1GX1A 3M84A 2GLZA 1FSZA 3JAWA 4XCQA 4BT7A 3ZP4A 4NQ3A 3RYCB 2CHTA 2UYNB 4ZOLB 3G71F 3VIUA 4B5CA 5LA6A 1YHQF 3WXMB 4X20B 5GONB 4NWOB 5CB4A 1VQKF 4FFBB 4KWEA 4TV9B 4EI8A 4U39A 1K73H 3KHNA 3JARB 1TVKA 4O4HB 5LYJB 3CCSF 3M4SA 4ZI7A 5HXZA 4O4JB 3TD3A 4O2AB 2R6R1 4EI9A 3DDNA 4ZHYB 3PLAC 3C9TA 3LFOA 5GANK 3MQWA 2Q1YA 5IJ9B 2OTLF 2WALA 4EB6B 3ZOPA 3J7AR 3RYHB 3LDTA 4G88A 1IV1A 4IIJA 1DBFA 3VO8A 5JH7A 2HQSC 3N2KB 4G4WA 3CMAF 2QA4F 1W42A 3CC7F 5IJ0B 3CCVF 5HY2A 1Q86H 2HX0A 2YXZA 3N4ZA 2R751 1YGYA 3RYFB 3HJWC 1T0KB 1IV2A 5B8FA 2ZOVA 3IEWA 2FC3A 3CCQF 3F0FA 5EIBC 1Q7YH 4TUYB 2PMPA 5CA1A 5ITZA 1GO0A 3HKDA 4ZHQB 1YQNA 4I4TB 1M1KH 4LNUB 3V7EA 2AMTA 1KQSF 3SIUA 4IHJB 3VCZA 1IV4A 3CMEF 3RA5A 3OBWA 2NMUA 2RHJA 3JASB 5EYPB 5JCOA 5KMGB 3QHDA 5HWEA 4F6RA 1H47A 4ZHVA 4RHAA 2ALEA 4TV8A 2HS4A 3RYIB 1W3EX 1W41A 3WJRA 2G9IA 3LWVC 4C8IA 5BMVA 3WGLA 3C9SA 3FBAA 3JAKB 2BTOA 2DT4A 4HNAB 3JVHA 5EIBD 3E20B 3IEQA 3VMFB 3WGMA 5LP6A 2CZWA 4X1KB 4WBNB 5EB0A 2KGWA 1XHOA 2RHOA 1YJWF 5GINC 3C9UA 3LYBA 1W581 5IYZB 4O4IA 3E22A 1FNKA 3T80A 3VYSC 3D54A 4X1YB 3MBMA 1ODEA 5FLXM 3PAFA 3Q8HA 4U3JB 3HKEB 1KNKA 2DYYA 2OTMA 5HP8A 3LMEA 5G4VC 4DRXB 1TUBA 5KX5A 1IPAA 4NUTA 1YIJF
chains in the Genus database with same CATH topology
2HX0A 2DT4A 4BT7A 4BT3A 4BT2A 2H6LA 1XV2A 2P6YA 4BT6A 3HWUA 3HTNA 4BT4A 2NMUA 4BT5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HX0 A;  2DT4 A;  4BT7 A;  4BT3 A;  4BT2 A;  2H6L A;  1XV2 A;  2P6Y A;  4BT6 A;  3HWU A;  3HTN A;  4BT4 A;  2NMU A;  4BT5 A; 
#chains in the Genus database with same CATH topology
 2CW4 A;  2F9Z C;  5HY0 A;  4BT6 A;  2QEX F;  5EWR A;  1M90 H;  1OFU A;  3VTI C;  1YI2 F;  1FNJ A;  2BO1 A;  3VYT C;  3S0H A;  1X25 A;  5C8Y A;  3CD6 F;  3WPW A;  1JFF A;  3R0P A;  1VQM F;  4C8G A;  4ZHW A;  1U3L A;  1ONI A;  3LWQ C;  1VQN F;  2HRY A;  3CYP B;  3J80 M;  2K1S A;  2OHW A;  3RYC A;  1U3P A;  2UYN A;  4ZOL A;  5EB1 B;  3TD4 A;  5J2T B;  3C9R A;  1RQ7 A;  4X20 A;  3CPW F;  5GON A;  5JCO C;  1QD9 A;  1RQ2 A;  2Z1U A;  2AIZ P;  4FFB A;  5LXT B;  2AIF A;  4RQO A;  4B62 A;  3JAT B;  3JAL B;  4TV9 A;  5LOV B;  1KNJ A;  3S0Y A;  5G4U C;  2HS3 A;  3FPI A;  3ELC A;  3JAR A;  4O4H A;  5LYJ A;  2VAM A;  2I6R A;  3S06 A;  4C4W C;  2VAW A;  3SIV A;  1VH8 A;  2IAF A;  2ZOD A;  4O4J A;  1GZ0 A;  4O2A A;  1VQ9 F;  1GO1 A;  1JY8 A;  3VOA A;  3QUW A;  5AVM A;  3HAX D;  5IJ9 A;  2L26 A;  1N8R H;  3MCQ A;  3IMP A;  4EB6 A;  3RYH A;  2OZB A;  2VGN A;  3NVI B;  3ZP7 A;  3K2X A;  4BT4 A;  3TD5 A;  3FFM A;  3N2K A;  4G4Z A;  2CWJ A;  5IJ0 A;  2CHS A;  3KIZ A;  5J2U B;  4BY9 D;  2KG4 A;  1SA0 B;  3UT5 B;  3HTN A;  3U0O A;  3N2G B;  3RYF A;  3CCJ F;  3HKB B;  5EAZ A;  3G6E F;  3B6N A;  4I50 B;  1H7M A;  3F0E A;  1W59 A;  2W8B C;  1RLU A;  4TUY A;  1UI9 A;  4YJ2 B;  2BTU A;  2GVI A;  3NK6 A;  3RA6 A;  5IT9 M;  2MQE A;  1QVF F;  1YJN F;  4ZHQ A;  4I4T A;  4M8I A;  4LNU A;  4O2B B;  2LBT A;  1FFX B;  2ZAU A;  4O4L B;  1VQO F;  4IHJ A;  4BVR A;  2EWC A;  3GTZ A;  5JQG B;  1U43 A;  3JAS A;  5EYP A;  5MN4 A;  5KMG A;  3CCE F;  1R1M A;  1JJ2 F;  2OTJ F;  1JN1 A;  1QVG F;  3D00 A;  1E7K A;  1CK2 A;  2IQQ A;  2VGM A;  3OBY A;  3FD5 A;  1W55 A;  4YJ3 B;  2LBW A;  5FJ4 C;  3P10 A;  3BYQ A;  3RYI A;  5HY4 A;  4E6E A;  2H8C A;  1CLI A;  1W5A A;  3MDO A;  2ZVZ A;  4C8E A;  4B45 A;  2HRU A;  1K8A H;  1VQ6 F;  3VYU C;  3JAK A;  1VQL F;  4HNA A;  3HKC B;  2RHH A;  3G4S F;  1OAP A;  2HP0 B;  5CA0 B;  4R40 B;  3GHZ A;  4X1K A;  4WBN A;  5GIP C;  2UZH A;  1VQ8 F;  3WPX A;  4X1I B;  3IKE A;  1W40 A;  3LWR C;  4G4X A;  1VQ4 F;  4G4V A;  1PXW A;  2RB9 A;  3L7Q A;  2LCA A;  4C82 A;  2QI2 A;  5JVD B;  4I55 B;  1Q8R A;  5IYZ A;  5EZY B;  5GIO C;  3JAM M;  4X1Y A;  5HXU A;  3F6M A;  5HY1 A;  2KTV A;  4U3J A;  3HKE A;  3IKF A;  3VOB A;  1VQP F;  3LWP C;  5FNV B;  1COM A;  4DRX A;  3JAW B;  3NK7 A;  3CXC F;  3I3F A;  1RA4 A;  3CPQ A;  3IR9 A;  5LA6 B;  1IV3 A;  3OW2 F;  4B46 A;  1U40 A;  2KTU A;  4X3L A;  1NMU B;  5CB4 B;  3CYQ A;  3S02 A;  3D01 A;  3V3T A;  4C81 A;  3F0G A;  1CN7 A;  5MN5 A;  1X7P A;  2UYK A;  3AGK A;  3DC2 A;  3K14 A;  1TVK B;  2LBX A;  2Q1X A;  2UYJ A;  1W2B F;  4ZI7 B;  3CCR F;  3NMU C;  5EO3 A;  3P0Z A;  3S0W A;  3S03 A;  3V7Q A;  5MN6 A;  5J2T A;  1RLG A;  2VAP A;  3HWU A;  3C8L A;  3CB2 A;  4IIJ B;  5LXT A;  5JH7 B;  3JAT A;  3JAL A;  5LOV A;  2V9Y A;  4G4Y A;  5LP6 C;  3MCA B;  1X52 A;  3NVK E;  5A2Q M;  2BTQ B;  3WJQ A;  3CC2 F;  1SDS A;  1J7H A;  2Z1T A;  1S72 F;  3N4Y A;  3ON1 A;  4BVQ A;  4DXD A;  3WGJ A;  3QTY A;  5CA1 B;  3J81 M;  1QAH A;  1VQ5 F;  5ITZ B;  2UYP A;  1VK3 A;  2N48 A;  3K0T A;  3HKD B;  4BVT A;  1SZQ A;  3CCM F;  2Z01 A;  1Z5V A;  3F0D A;  2HVY D;  4BT2 A;  2H6L A;  2JNB A;  1VQV A;  3KJJ A;  1VQ7 F;  4BW0 B;  5J2U A;  4X3M A;  1SA0 A;  2HS0 A;  3UT5 A;  3N2G A;  4F6R B;  3HKB A;  3I56 F;  4I50 A;  1W57 A;  2ZF8 A;  3OON A;  1PF5 A;  2GZL A;  3V4D A;  1Z5W A;  2I6D A;  3ZO8 A;  4LCK A;  1W5F A;  3KE1 A;  4TV8 B;  1T0A A;  3ERN A;  1YJ9 F;  2IG8 A;  4YJ2 A;  1XBI A;  3GYQ A;  1VHA A;  1Q81 H;  3K12 A;  5BMV B;  3RE3 A;  1X7O A;  2ZVY A;  4O2B A;  1FFX A;  4O4L A;  4PWT A;  4ERH A;  5GAP K;  5JQG A;  5LP6 B;  2FGY A;  4BT3 A;  2P6Y A;  1K9M H;  1QU9 A;  1XRG A;  2HP3 A;  3EOR A;  3M1X A;  3WGN A;  5DCV A;  1UFY A;  3CCL F;  3FD6 A;  1NJI H;  4YJ3 A;  5HP7 A;  4ZK7 A;  3CCU F;  2B33 A;  4EI7 A;  3JCM M;  4O4I B;  3E22 B;  3LWO C;  3WJP A;  3WGK A;  2H8E A;  1DT9 A;  3HKC A;  1W5B A;  1NQ3 A;  1TUB B;  2HP0 A;  5KX5 B;  5CA0 A;  2VXY A;  2PHN A;  1XV2 A;  3KJK A;  2Z1F A;  3I55 F;  4X1I A;  1YIT F;  3VI6 A;  2CVL A;  2CSL A;  1KD1 H;  3E1Y A;  4TZZ A;  2RHL A;  4BT5 A;  1ZWZ A;  3CC4 F;  2QTP A;  3O85 A;  5JVD A;  4I55 A;  3ESJ A;  3I7T A;  5EZY A;  3P4E A;  1Q82 H;  1W5E A;  1H48 A;  5C8Y B;  2YYE A;  1JFF B;  3CG6 A;  2Z1E A;  4BVS A;  1JD1 A;  1KC8 H;  5FNV A;  1GX1 A;  3M84 A;  2GLZ A;  1FSZ A;  3JAW A;  4XCQ A;  4BT7 A;  3ZP4 A;  4NQ3 A;  3RYC B;  2CHT A;  2UYN B;  4ZOL B;  3G71 F;  3VIU A;  4B5C A;  5LA6 A;  1YHQ F;  3WXM B;  4X20 B;  5GON B;  4NWO B;  5CB4 A;  1VQK F;  4FFB B;  4KWE A;  4TV9 B;  4EI8 A;  4U39 A;  1K73 H;  3KHN A;  3JAR B;  1TVK A;  4O4H B;  5LYJ B;  3CCS F;  3M4S A;  4ZI7 A;  5HXZ A;  4O4J B;  3TD3 A;  4O2A B;  2R6R 1;  4EI9 A;  3DDN A;  4ZHY B;  3PLA C;  3C9T A;  3LFO A;  5GAN K;  3MQW A;  2Q1Y A;  5IJ9 B;  2OTL F;  2WAL A;  4EB6 B;  3ZOP A;  3J7A R;  3RYH B;  3LDT A;  4G88 A;  1IV1 A;  4IIJ A;  1DBF A;  3VO8 A;  5JH7 A;  2HQS C;  3N2K B;  4G4W A;  3CMA F;  2QA4 F;  1W42 A;  3CC7 F;  5IJ0 B;  3CCV F;  5HY2 A;  1Q86 H;  2HX0 A;  2YXZ A;  3N4Z A;  2R75 1;  1YGY A;  3RYF B;  3HJW C;  1T0K B;  1IV2 A;  5B8F A;  2ZOV A;  3IEW A;  2FC3 A;  3CCQ F;  3F0F A;  5EIB C;  1Q7Y H;  4TUY B;  2PMP A;  5CA1 A;  5ITZ A;  1GO0 A;  3HKD A;  4ZHQ B;  1YQN A;  4I4T B;  1M1K H;  4LNU B;  3V7E A;  2AMT A;  1KQS F;  3SIU A;  4IHJ B;  3VCZ A;  1IV4 A;  3CME F;  3RA5 A;  3OBW A;  2NMU A;  2RHJ A;  3JAS B;  5EYP B;  5JCO A;  5KMG B;  3QHD A;  5HWE A;  4F6R A;  1H47 A;  4ZHV A;  4RHA A;  2ALE A;  4TV8 A;  2HS4 A;  3RYI B;  1W3E X;  1W41 A;  3WJR A;  2G9I A;  3LWV C;  4C8I A;  5BMV A;  3WGL A;  3C9S A;  3FBA A;  3JAK B;  2BTO A;  2DT4 A;  4HNA B;  3JVH A;  5EIB D;  3E20 B;  3IEQ A;  3VMF B;  3WGM A;  5LP6 A;  2CZW A;  4X1K B;  4WBN B;  5EB0 A;  2KGW A;  1XHO A;  2RHO A;  1YJW F;  5GIN C;  3C9U A;  3LYB A;  1W58 1;  5IYZ B;  4O4I A;  3E22 A;  1FNK A;  3T80 A;  3VYS C;  3D54 A;  4X1Y B;  3MBM A;  1ODE A;  5FLX M;  3PAF A;  3Q8H A;  4U3J B;  3HKE B;  1KNK A;  2DYY A;  2OTM A;  5HP8 A;  3LME A;  5G4V C;  4DRX B;  1TUB A;  5KX5 A;  1IPA A;  4NUT A;  1YIJ F; 
#chains in the Genus database with same CATH homology
 2HX0 A;  2DT4 A;  4BT7 A;  4BT3 A;  4BT2 A;  2H6L A;  1XV2 A;  2P6Y A;  4BT6 A;  3HWU A;  3HTN A;  4BT4 A;  2NMU A;  4BT5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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