4BT2A

Acetolactate decarboxylase with a bound 1,2-ethanediol
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
237
structure length
237
Chain Sequence
APKNVLFQYSTINALMLGQFEGDLTLKDLKLRGDMGLGTINDLDGEMIQMGTKFYQIDSTGKLSELPESVKTPFAVTTHFEPKEKTTLTNVQDYNQLTKMLEEKFENKNVFYAVKLTGTFKMVKARTVPKQTRPYPQLTEVTKKQSEFEFKNVKGTLIGFYTPNYAAALNVPGFHLHFITEDKTSGGHVLNLQFDNANLEISPIHEFDVQLPHTDDFAHSDLTQVTTSQVHQAESER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords ALPHA-ACETOLACTATE DECARBOXYLASE
publication title Structure and Mechanism of Acetolactate Decarboxylase
pubmed doi rcsb
source organism Brevibacillus brevis
total genus 74
structure length 237
sequence length 237
ec nomenclature ec 4.1.1.5: Acetolactate decarboxylase.
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03306 AAL_decarboxy Alpha-acetolactate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1330.80 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 4bt2A02
3.30.1330.80 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 4bt2A01
2NMUA 2H6LA 4BT5A 4BT3A 2HX0A 4BT2A 1XV2A 4BT6A 3HTNA 2P6YA 4BT4A 4BT7A 3HWUA 2DT4A
chains in the Genus database with same CATH superfamily
5LYJA 2IQQA 1KQSF 2BO1A 3E20B 1H47A 2RHJA 3HKBB 3CC2F 1X52A 4BT2A 4O2BA 3CYQA 4O4HA 3J80M 3D01A 3Q8HA 1UFYA 2UZHA 3F6MA 4ZK7A 1N8RH 3NK6A 4I55B 2GVIA 2Q1YA 2KG4A 4EB6A 3NVKE 5GIOC 4X20A 5JVDA 5HY0A 5GIPC 3V4DA 5EZYB 3WJPA 1FFXB 3RYHB 5EIBD 3P4EA 5MN5A 3C9RA 3JVHA 3CCLF 1YJ9F 3S0WA 2ZF8A 3CXCF 3JALA 4B62A 2VAPA 1NQ3A 2RHLA 1GO1A 3RYIA 3CCUF 1JY8A 1NMUB 2EWCA 5CA0B 2ZODA 1H48A 5EAZA 3M4SA 2I6RA 4BT5A 3VYUC 3B6NA 4ZHYB 2ZAUA 3MQWA 1XV2A 3C9SA 3ZP7A 4C81A 4WBNA 5JH7B 5BMVB 1U40A 3CCQF 3HJWC 1ZWZA 5EIBC 4X1IA 2RHHA 3V7EA 4YJ3A 3V7QA 1JFFB 4TV9A 4G4ZA 4X1YB 1Z5WA 4ZHQB 2LBWA 1W5BA 3JAWB 3DC2A 3CPWF 2ZVZA 1QVGF 5KX5B 1T0KB 3F0DA 3HAXD 4C82A 2GLZA 2HS4A 3OW2F 4TZZA 1Q8RA 1PXWA 3WPXA 5HP8A 4O2AA 5GANK 3FD6A 3L7QA 4O4IA 3T80A 1YITF 3WJQA 1U43A 3JARA 3ZO8A 1SA0B 4BVTA 3GHZA 4G88A 3VTIC 2CW4A 1JN1A 2OZBA 3WJRA 4HNAA 1VQMF 5LP6B 1VQ6F 4C8IA 4I50A 2OTJF 3D54A 1VQ9F 5J2TB 2KTUA 3JAKB 3E1YA 4ZHVA 1X7PA 5C8YB 3MBMA 3CCRF 1PF5A 1IV2A 2YXZA 3JASB 3UT5A 3IR9A 5HXUA 2JNBA 5KMGB 1QAHA 3WXMB 3AGKA 1CLIA 1FNKA 4F6RA 5ITZA 5JQGA 3NVIB 2VAWA 5IJ9B 1Q86H 4I4TB 5LA6A 3VYTC 3J81M 1TUBB 4BT3A 4BVQA 1YHQF 4O4JB 5HP7A 2H8EA 2HQSC 2RB9A 2R751 3VIUA 4EI9A 2UYNA 4C4WC 2BTOA 2BTUA 5FNVA 4B45A 3C9TA 1ONIA 2CVLA 4FFBA 3LWOC 3CCEF 2UYJA 3HKDB 3IKEA 1W55A 4TUYB 3S0YA 1YIJF 4IHJB 5B8FA 2HS0A 1KD1H 3SIUA 1VQOF 4NWOB 1IV3A 1W5FA 2WALA 3EORA 4IHJA 3CCJF 4G4VA 4BY9D 1U3PA 4O2BB 3ON1A 5IJ0A 3KHNA 1W581 1Z5VA 1TVKB 3TD4A 5EZYA 3N4ZA 1FFXA 2QI2A 3OBWA 4X1KB 1Q81H 1UI9A 3GTZA 4BVRA 4EB6B 5IT9M 2CHTA 2HP0B 5AVMA 3LWRC 4O4LB 1GZ0A 3I56F 1YI2F 1RLGA 3TD5A 1E7KA 2FGYA 2ZVYA 2ALEA 3LWVC 3CYPB 1YJWF 3KIZA 1K8AH 3CB2A 3JALB 2UYKA 2IG8A 5CA0A 2IAFA 1YGYA 4TV8A 3C8LA 2HS3A 3RA6A 4EI8A 3KJJA 1KNJA 3JATB 2PHNA 3ZOPA 4G4YA 1T0AA 4BW0B 3M84A 3BYQA 3MDOA 3N2GB 3CPQA 5JH7A 3VI6A 5BMVA 1VQPF 3TD3A 2HX0A 1W2BF 3RYFA 1FNJA 1OAPA 4ZOLB 1JFFA 4X1YA 4KWEA 1XBIA 3ESJA 4X1IB 5G4VC 3NMUC 2BTQB 3IEWA 4YJ3B 5KX5A 4TV9B 5EB0A 5J2UB 3U0OA 4BT7A 1S72F 3D00A 3CCVF 3CG6A 3LWQC 5GINC 1IV4A 1Q82H 1CN7A 3O85A 3FFMA 4X3MA 4YJ2A 3S06A 3RYCA 3N2KA 2B33A 1GX1A 2PMPA 2CSLA 4O2AB 3KE1A 5EYPB 2I6DA 5HWEA 4LCKA 2Z1TA 5EO3A 1H7MA 2FC3A 2VAMA 2N48A 3VMFB 3LYBA 1VH8A 3K12A 5CA1A 4C8GA 1W59A 4RHAA 5HY4A 3JARB 5JCOA 3WGJA 3HKCB 5LP6A 3SIVA 2DYYA 4IIJA 3G4SF 3S0HA 5J2TA 3M1XA 2CWJA 4HNAB 5LOVB 3LDTA 3ERNA 2HP3A 3LMEA 5C8YA 1K73H 4ZHWA 3I55F 3G6EF 4BT4A 5KMGA 3E22B 1VQLF 3HWUA 5GONA 3V3TA 3FPIA 3WGMA 4ZI7A 4B5CA 4LNUA 4DXDA 1VK3A 1W42A 5IJ9A 1J7HA 3MCQA 3CMEF 4DRXA 3RA5A 1OFUA 2K1SA 3HKEA 3JCMM 2LCAA 1KNKA 4U3JB 5CB4A 2H8CA 1YQNA 4M8IA 5HXZA 1JD1A 4G4XA 1VQ5F 3OONA 2VXYA 5IYZB 3I7TA 5LXTB 2VGMA 3HKBA 1RLUA 2KTVA 3K14A 3VOBA 5LYJB 2Q1XA 4TUYA 5MN6A 2OTMA 2R6R1 4I55A 1QVFF 1VQ4F 5G4UC 1RQ7A 1QU9A 3PAFA 3F0FA 4O4HB 3G71F 4U39A 2LBXA 1X25A 2AMTA 3P0ZA 1VQ8F 1IV1A 2VGNA 3RYHA 3JAMM 1TVKA 4X20B 5A2QM 5JVDB 3VO8A 4NUTA 4X1KA 2CZWA 3LFOA 1VQNF 3OBYA 4BVSA 3CCSF 3MCAB 5IJ0B 2HP0A 1VHAA 3KJKA 2RHOA 3WPWA 2ZOVA 4O4LA 1VQVA 1W5AA 1X7OA 2YYEA 1W40A 2MQEA 3CMAF 2CHSA 5EWRA 2GZLA 3QTYA 1SZQA 1VQ7F 4R40B 3RYIB 2H6LA 1ODEA 1GO0A 3VCZA 2V9YA 3ZP4A 3GYQA 3JATA 1COMA 2Z1FA 3IEQA 1W41A 2W8BC 3FD5A 1W3EX 3I3FA 1FSZA 4X3LA 3IMPA 4TV8B 2DT4A 3N2GA 1KC8H 4WBNB 4ZHQA 3CC4F 1M90H 3JAWA 4ZOLA 5FLXM 3IKFA 1VQKF 2F9ZC 3PLAC 1RQ2A 3LWPC 3HTNA 3RYFB 2HRUA 2NMUA 4XCQA 3F0GA 3S03A 1R1MA 3P10A 5HY1A 4EI7A 5J2UA 3S02A 1W57A 5MN4A 3CD6F 3RE3A 2HVYD 2QEXF 4B46A 1Q7YH 1SDSA 3WGLA 4E6EA 3FBAA 1U3LA 1K9MH 3CCMF 1SA0A 5FJ4C 4O4IB 3F0EA 5EYPA 1CK2A 4YJ2B 1QD9A 3WGKA 3RYCB 3N2KB 2P6YA 4ERHA 5HY2A 3VYSC 1RA4A 3DDNA 4C8EA 3C9UA 1XRGA 5EB1B 1W5EA 4BT6A 3JAKA 3NK7A 2QA4F 2KGWA 3ELCA 3HKCA 1DBFA 1JJ2F 5GAPK 3J7AR 5CA1B 2HRYA 4I50B 5DCVA 2AIZP 3JASA 2L26A 2QTPA 2Z1EA 5LOVA 1M1KH 1NJIH 1IPAA 2UYPA 4IIJB 3N4YA 1XHOA 3UT5B 3E22A 4I4TA 1TUBA 5JCOC 5LP6C 2AIFA 3QUWA 4G4WA 4O4JA 2Z01A 4F6RB 5ITZB 3K0TA 3R0PA 5JQGB 2LBTA 2G9IA 5GONB 1DT9A 3CC7F 2OHWA 4ZI7B 3QHDA 5LA6B 3VOAA 3WGNA 4LNUB 1YJNF 3K2XA 4U3JA 2OTLF 4NQ3A 4RQOA 2Z1UA 2UYNB 4PWTA 3HKDA 4DRXB 5IYZA 5FNVB 3HKEB 5CB4B 5LXTA 4FFBB
chains in the Genus database with same CATH topology
2NMUA 2H6LA 4BT5A 4BT3A 2HX0A 4BT2A 1XV2A 4BT6A 3HTNA 2P6YA 4BT4A 4BT7A 3HWUA 2DT4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NMU A;  2H6L A;  4BT5 A;  4BT3 A;  2HX0 A;  4BT2 A;  1XV2 A;  4BT6 A;  3HTN A;  2P6Y A;  4BT4 A;  4BT7 A;  3HWU A;  2DT4 A; 
#chains in the Genus database with same CATH topology
 5LYJ A;  2IQQ A;  1KQS F;  2BO1 A;  3E20 B;  1H47 A;  2RHJ A;  3HKB B;  3CC2 F;  1X52 A;  4BT2 A;  4O2B A;  3CYQ A;  4O4H A;  3J80 M;  3D01 A;  3Q8H A;  1UFY A;  2UZH A;  3F6M A;  4ZK7 A;  1N8R H;  3NK6 A;  4I55 B;  2GVI A;  2Q1Y A;  2KG4 A;  4EB6 A;  3NVK E;  5GIO C;  4X20 A;  5JVD A;  5HY0 A;  5GIP C;  3V4D A;  5EZY B;  3WJP A;  1FFX B;  3RYH B;  5EIB D;  3P4E A;  5MN5 A;  3C9R A;  3JVH A;  3CCL F;  1YJ9 F;  3S0W A;  2ZF8 A;  3CXC F;  3JAL A;  4B62 A;  2VAP A;  1NQ3 A;  2RHL A;  1GO1 A;  3RYI A;  3CCU F;  1JY8 A;  1NMU B;  2EWC A;  5CA0 B;  2ZOD A;  1H48 A;  5EAZ A;  3M4S A;  2I6R A;  4BT5 A;  3VYU C;  3B6N A;  4ZHY B;  2ZAU A;  3MQW A;  1XV2 A;  3C9S A;  3ZP7 A;  4C81 A;  4WBN A;  5JH7 B;  5BMV B;  1U40 A;  3CCQ F;  3HJW C;  1ZWZ A;  5EIB C;  4X1I A;  2RHH A;  3V7E A;  4YJ3 A;  3V7Q A;  1JFF B;  4TV9 A;  4G4Z A;  4X1Y B;  1Z5W A;  4ZHQ B;  2LBW A;  1W5B A;  3JAW B;  3DC2 A;  3CPW F;  2ZVZ A;  1QVG F;  5KX5 B;  1T0K B;  3F0D A;  3HAX D;  4C82 A;  2GLZ A;  2HS4 A;  3OW2 F;  4TZZ A;  1Q8R A;  1PXW A;  3WPX A;  5HP8 A;  4O2A A;  5GAN K;  3FD6 A;  3L7Q A;  4O4I A;  3T80 A;  1YIT F;  3WJQ A;  1U43 A;  3JAR A;  3ZO8 A;  1SA0 B;  4BVT A;  3GHZ A;  4G88 A;  3VTI C;  2CW4 A;  1JN1 A;  2OZB A;  3WJR A;  4HNA A;  1VQM F;  5LP6 B;  1VQ6 F;  4C8I A;  4I50 A;  2OTJ F;  3D54 A;  1VQ9 F;  5J2T B;  2KTU A;  3JAK B;  3E1Y A;  4ZHV A;  1X7P A;  5C8Y B;  3MBM A;  3CCR F;  1PF5 A;  1IV2 A;  2YXZ A;  3JAS B;  3UT5 A;  3IR9 A;  5HXU A;  2JNB A;  5KMG B;  1QAH A;  3WXM B;  3AGK A;  1CLI A;  1FNK A;  4F6R A;  5ITZ A;  5JQG A;  3NVI B;  2VAW A;  5IJ9 B;  1Q86 H;  4I4T B;  5LA6 A;  3VYT C;  3J81 M;  1TUB B;  4BT3 A;  4BVQ A;  1YHQ F;  4O4J B;  5HP7 A;  2H8E A;  2HQS C;  2RB9 A;  2R75 1;  3VIU A;  4EI9 A;  2UYN A;  4C4W C;  2BTO A;  2BTU A;  5FNV A;  4B45 A;  3C9T A;  1ONI A;  2CVL A;  4FFB A;  3LWO C;  3CCE F;  2UYJ A;  3HKD B;  3IKE A;  1W55 A;  4TUY B;  3S0Y A;  1YIJ F;  4IHJ B;  5B8F A;  2HS0 A;  1KD1 H;  3SIU A;  1VQO F;  4NWO B;  1IV3 A;  1W5F A;  2WAL A;  3EOR A;  4IHJ A;  3CCJ F;  4G4V A;  4BY9 D;  1U3P A;  4O2B B;  3ON1 A;  5IJ0 A;  3KHN A;  1W58 1;  1Z5V A;  1TVK B;  3TD4 A;  5EZY A;  3N4Z A;  1FFX A;  2QI2 A;  3OBW A;  4X1K B;  1Q81 H;  1UI9 A;  3GTZ A;  4BVR A;  4EB6 B;  5IT9 M;  2CHT A;  2HP0 B;  5AVM A;  3LWR C;  4O4L B;  1GZ0 A;  3I56 F;  1YI2 F;  1RLG A;  3TD5 A;  1E7K A;  2FGY A;  2ZVY A;  2ALE A;  3LWV C;  3CYP B;  1YJW F;  3KIZ A;  1K8A H;  3CB2 A;  3JAL B;  2UYK A;  2IG8 A;  5CA0 A;  2IAF A;  1YGY A;  4TV8 A;  3C8L A;  2HS3 A;  3RA6 A;  4EI8 A;  3KJJ A;  1KNJ A;  3JAT B;  2PHN A;  3ZOP A;  4G4Y A;  1T0A A;  4BW0 B;  3M84 A;  3BYQ A;  3MDO A;  3N2G B;  3CPQ A;  5JH7 A;  3VI6 A;  5BMV A;  1VQP F;  3TD3 A;  2HX0 A;  1W2B F;  3RYF A;  1FNJ A;  1OAP A;  4ZOL B;  1JFF A;  4X1Y A;  4KWE A;  1XBI A;  3ESJ A;  4X1I B;  5G4V C;  3NMU C;  2BTQ B;  3IEW A;  4YJ3 B;  5KX5 A;  4TV9 B;  5EB0 A;  5J2U B;  3U0O A;  4BT7 A;  1S72 F;  3D00 A;  3CCV F;  3CG6 A;  3LWQ C;  5GIN C;  1IV4 A;  1Q82 H;  1CN7 A;  3O85 A;  3FFM A;  4X3M A;  4YJ2 A;  3S06 A;  3RYC A;  3N2K A;  2B33 A;  1GX1 A;  2PMP A;  2CSL A;  4O2A B;  3KE1 A;  5EYP B;  2I6D A;  5HWE A;  4LCK A;  2Z1T A;  5EO3 A;  1H7M A;  2FC3 A;  2VAM A;  2N48 A;  3VMF B;  3LYB A;  1VH8 A;  3K12 A;  5CA1 A;  4C8G A;  1W59 A;  4RHA A;  5HY4 A;  3JAR B;  5JCO A;  3WGJ A;  3HKC B;  5LP6 A;  3SIV A;  2DYY A;  4IIJ A;  3G4S F;  3S0H A;  5J2T A;  3M1X A;  2CWJ A;  4HNA B;  5LOV B;  3LDT A;  3ERN A;  2HP3 A;  3LME A;  5C8Y A;  1K73 H;  4ZHW A;  3I55 F;  3G6E F;  4BT4 A;  5KMG A;  3E22 B;  1VQL F;  3HWU A;  5GON A;  3V3T A;  3FPI A;  3WGM A;  4ZI7 A;  4B5C A;  4LNU A;  4DXD A;  1VK3 A;  1W42 A;  5IJ9 A;  1J7H A;  3MCQ A;  3CME F;  4DRX A;  3RA5 A;  1OFU A;  2K1S A;  3HKE A;  3JCM M;  2LCA A;  1KNK A;  4U3J B;  5CB4 A;  2H8C A;  1YQN A;  4M8I A;  5HXZ A;  1JD1 A;  4G4X A;  1VQ5 F;  3OON A;  2VXY A;  5IYZ B;  3I7T A;  5LXT B;  2VGM A;  3HKB A;  1RLU A;  2KTV A;  3K14 A;  3VOB A;  5LYJ B;  2Q1X A;  4TUY A;  5MN6 A;  2OTM A;  2R6R 1;  4I55 A;  1QVF F;  1VQ4 F;  5G4U C;  1RQ7 A;  1QU9 A;  3PAF A;  3F0F A;  4O4H B;  3G71 F;  4U39 A;  2LBX A;  1X25 A;  2AMT A;  3P0Z A;  1VQ8 F;  1IV1 A;  2VGN A;  3RYH A;  3JAM M;  1TVK A;  4X20 B;  5A2Q M;  5JVD B;  3VO8 A;  4NUT A;  4X1K A;  2CZW A;  3LFO A;  1VQN F;  3OBY A;  4BVS A;  3CCS F;  3MCA B;  5IJ0 B;  2HP0 A;  1VHA A;  3KJK A;  2RHO A;  3WPW A;  2ZOV A;  4O4L A;  1VQV A;  1W5A A;  1X7O A;  2YYE A;  1W40 A;  2MQE A;  3CMA F;  2CHS A;  5EWR A;  2GZL A;  3QTY A;  1SZQ A;  1VQ7 F;  4R40 B;  3RYI B;  2H6L A;  1ODE A;  1GO0 A;  3VCZ A;  2V9Y A;  3ZP4 A;  3GYQ A;  3JAT A;  1COM A;  2Z1F A;  3IEQ A;  1W41 A;  2W8B C;  3FD5 A;  1W3E X;  3I3F A;  1FSZ A;  4X3L A;  3IMP A;  4TV8 B;  2DT4 A;  3N2G A;  1KC8 H;  4WBN B;  4ZHQ A;  3CC4 F;  1M90 H;  3JAW A;  4ZOL A;  5FLX M;  3IKF A;  1VQK F;  2F9Z C;  3PLA C;  1RQ2 A;  3LWP C;  3HTN A;  3RYF B;  2HRU A;  2NMU A;  4XCQ A;  3F0G A;  3S03 A;  1R1M A;  3P10 A;  5HY1 A;  4EI7 A;  5J2U A;  3S02 A;  1W57 A;  5MN4 A;  3CD6 F;  3RE3 A;  2HVY D;  2QEX F;  4B46 A;  1Q7Y H;  1SDS A;  3WGL A;  4E6E A;  3FBA A;  1U3L A;  1K9M H;  3CCM F;  1SA0 A;  5FJ4 C;  4O4I B;  3F0E A;  5EYP A;  1CK2 A;  4YJ2 B;  1QD9 A;  3WGK A;  3RYC B;  3N2K B;  2P6Y A;  4ERH A;  5HY2 A;  3VYS C;  1RA4 A;  3DDN A;  4C8E A;  3C9U A;  1XRG A;  5EB1 B;  1W5E A;  4BT6 A;  3JAK A;  3NK7 A;  2QA4 F;  2KGW A;  3ELC A;  3HKC A;  1DBF A;  1JJ2 F;  5GAP K;  3J7A R;  5CA1 B;  2HRY A;  4I50 B;  5DCV A;  2AIZ P;  3JAS A;  2L26 A;  2QTP A;  2Z1E A;  5LOV A;  1M1K H;  1NJI H;  1IPA A;  2UYP A;  4IIJ B;  3N4Y A;  1XHO A;  3UT5 B;  3E22 A;  4I4T A;  1TUB A;  5JCO C;  5LP6 C;  2AIF A;  3QUW A;  4G4W A;  4O4J A;  2Z01 A;  4F6R B;  5ITZ B;  3K0T A;  3R0P A;  5JQG B;  2LBT A;  2G9I A;  5GON B;  1DT9 A;  3CC7 F;  2OHW A;  4ZI7 B;  3QHD A;  5LA6 B;  3VOA A;  3WGN A;  4LNU B;  1YJN F;  3K2X A;  4U3J A;  2OTL F;  4NQ3 A;  4RQO A;  2Z1U A;  2UYN B;  4PWT A;  3HKD A;  4DRX B;  5IYZ A;  5FNV B;  3HKE B;  5CB4 B;  5LXT A;  4FFB B; 
#chains in the Genus database with same CATH homology
 2NMU A;  2H6L A;  4BT5 A;  4BT3 A;  2HX0 A;  4BT2 A;  1XV2 A;  4BT6 A;  3HTN A;  2P6Y A;  4BT4 A;  4BT7 A;  3HWU A;  2DT4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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