4BT2A

Acetolactate decarboxylase with a bound 1,2-ethanediol
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
237
structure length
237
Chain Sequence
APKNVLFQYSTINALMLGQFEGDLTLKDLKLRGDMGLGTINDLDGEMIQMGTKFYQIDSTGKLSELPESVKTPFAVTTHFEPKEKTTLTNVQDYNQLTKMLEEKFENKNVFYAVKLTGTFKMVKARTVPKQTRPYPQLTEVTKKQSEFEFKNVKGTLIGFYTPNYAAALNVPGFHLHFITEDKTSGGHVLNLQFDNANLEISPIHEFDVQLPHTDDFAHSDLTQVTTSQVHQAESER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and Mechanism of Acetolactate Decarboxylase
pubmed doi rcsb
source organism Brevibacillus brevis
molecule tags Lyase
molecule keywords ALPHA-ACETOLACTATE DECARBOXYLASE
total genus 74
structure length 237
sequence length 237
ec nomenclature ec 4.1.1.5: Acetolactate decarboxylase.
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03306 AAL_decarboxy Alpha-acetolactate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1330.80 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 4bt2A02
3.30.1330.80 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 4bt2A01
3HTNA 4BT6A 2HX0A 2H6LA 4BT4A 4BT5A 1XV2A 4BT2A 3HWUA 2P6YA 2NMUA 4BT3A 2DT4A 4BT7A
chains in the Genus database with same CATH superfamily
1VQPF 1COMA 3CCJF 1XV2A 3B6NA 4TV9A 4ZOLA 1VH8A 3K14A 3VO8A 2ZOVA 3VIUA 1W5BA 4BW0B 4O4LA 3CC2F 3IEWA 4EB6B 5JH7A 3WGNA 3S02A 3HKBA 2R751 4U3JB 2LBTA 3OW2F 4I4TA 3IMPA 4C8GA 3CCEF 3LYBA 4FFBA 3ZP7A 2MQEA 3CCVF 3WJQA 3ON1A 3NVKE 3I55F 1W41A 5KX5B 4KWEA 1VQ5F 1DBFA 3VMFB 5G4VC 1TUBB 1W581 3AGKA 3CMAF 4BT3A 1KNKA 3FPIA 2HP3A 5FNVA 2Z01A 1XHOA 4O4HA 1PF5A 1TUBA 4PWTA 1KD1H 4ZOLB 4C82A 3I56F 4I55A 3D54A 3WGJA 4BVQA 1VK3A 2VAMA 3D01A 4O2BB 5FLXM 4TUYB 3GHZA 4EI7A 4IHJA 3OBWA 2HS0A 3ESJA 5CB4A 4G4ZA 3PLAC 4U3JA 1YJ9F 3FBAA 5A2QM 4X1KA 4FFBB 3CCQF 5IJ0B 2IQQA 2UYNA 1W42A 3NVIB 4ZHQA 1IV4A 5LOVB 4EB6A 5C8YA 2HQSC 2B33A 3N4YA 2V9YA 3N4ZA 2DYYA 3UT5A 1U40A 2H8CA 4X3LA 2ALEA 4O2AA 5IJ9A 5KMGB 4ERHA 4BT4A 3G71F 5EZYB 1CK2A 5LXTA 2OTMA 4YJ3A 2Z1FA 2KTUA 3RYIB 5LYJB 5HY0A 4U39A 2RHHA 3T80A 5GAPK 1GO0A 3V4DA 3GTZA 1K73H 4I50B 3WXMB 3K2XA 3JAKB 2EWCA 1FFXA 3QTYA 1KQSF 1TVKB 4TV8A 5HXZA 4X1IA 1VQ8F 5LA6B 3WGKA 4ZHYB 1ODEA 4C81A 5LP6C 2UYJA 5JVDB 1RQ7A 1GO1A 3O85A 2BTOA 1X7PA 3WPXA 3NK6A 3M84A 3WPWA 5KX5A 1VQNF 2CWJA 3V7EA 2FGYA 3TD4A 2RHOA 1OAPA 2KG4A 2HRYA 3IEQA 5LXTB 3ELCA 2BTQB 1W5AA 2VAWA 3DC2A 5GIPC 2Q1XA 2KTVA 2YYEA 1TVKA 4X3MA 2CZWA 2LBXA 3FD5A 3JAWA 5B8FA 2RHJA 2RB9A 4BVRA 2I6DA 1Z5VA 1RA4A 5JQGA 4F6RA 3JAWB 3LWQC 4G88A 2VGMA 3C9TA 3GYQA 3SIUA 4BVSA 1IV1A 4ZHQB 5LOVA 1VQMF 2RHLA 3R0PA 4C8IA 2CVLA 4C8EA 5ITZB 1SDSA 3CPQA 5GIOC 3C8LA 1T0AA 1XBIA 3J81M 1JN1A 3M1XA 5HXUA 5EAZA 3CD6F 1QAHA 3VOAA 3C9UA 3LWOC 1QU9A 4WBNA 1SZQA 2Q1YA 3KHNA 4ZHVA 3CG6A 4DXDA 2R6R1 3JARB 4NWOB 3QHDA 3JAMM 1JFFB 3JVHA 3C9SA 3VCZA 4IIJA 5HY2A 3HTNA 4LCKA 1W5EA 5CA1B 2WALA 4DRXB 3CXCF 1NQ3A 4LNUA 2GZLA 1YHQF 2ZODA 5IT9M 2HP0B 3RYFB 2QTPA 1VQ4F 1X7OA 3MCQA 1N8RH 3CCLF 5JH7B 5HP7A 1U43A 2Z1UA 4B5CA 3HKCA 2CHTA 5GANK 3HKDA 2GVIA 4G4VA 3JATA 1QVGF 3N2GA 2UYKA 3VOBA 1IPAA 1H48A 5GONA 3HWUA 3EORA 5JCOC 5EB1B 1H47A 2OTJF 4BT6A 1K9MH 4O4JA 1DT9A 3LWVC 3P4EA 4BY9D 1FSZA 4C4WC 3WGLA 3F0GA 1VQOF 5LP6B 3S06A 3CPWF 2ZVYA 2F9ZC 3MCAB 1Q86H 3IR9A 2ZAUA 4HNAB 3F0FA 4EI8A 1RLGA 5LYJA 3L7QA 4IIJB 3C9RA 3ZO8A 5CA1A 2QI2A 2VXYA 3I3FA 2AIFA 2PHNA 4I4TB 4O4IA 4HNAA 3WGMA 1IV2A 4X20A 2UZHA 3RYFA 3MBMA 4X1IB 3E22B 3JCMM 1VHAA 2H6LA 3RA6A 5LA6A 3SIVA 4O4LB 5CA0A 5EYPB 1JY8A 3E22A 2W8BC 4RHAA 1U3LA 3V7QA 5CA0B 3N2GB 1Z5WA 1Q7YH 1YI2F 2CHSA 3V3TA 4BT2A 3E1YA 3JASA 3FD6A 5FJ4C 3CCRF 4XCQA 3TD5A 3K0TA 3RYCB 1M90H 1YGYA 3CYQA 4EI9A 4O2AB 3CC7F 1CN7A 3LFOA 5BMVA 4I55B 5MN6A 3CCUF 4DRXA 2OTLF 2HRUA 4TV9B 4IHJB 5JQGB 5EIBC 2NMUA 2BTUA 5AVMA 5EO3A 5IYZA 1U3PA 4X20B 2DT4A 4ZHWA 5IJ0A 4TZZA 1W57A 4BT5A 3S0WA 3HJWC 2I6RA 3JAKA 1UI9A 3RA5A 1X25A 1XRGA 2OHWA 3CYPB 1H7MA 3S0HA 2OZBA 5J2UB 3N2KA 2Z1TA 3RYHA 1W59A 2HS4A 3TD3A 3S03A 1ONIA 1YJWF 2Z1EA 3Q8HA 3S0YA 1CLIA 4G4YA 3J80M 2VAPA 2L26A 3JARA 4O4HB 5DCVA 1YIJF 3VYSC 5LP6A 5KMGA 3QUWA 5GINC 2JNBA 1NJIH 2IAFA 5BMVB 3LWPC 3E20B 1YJNF 3MDOA 4TV8B 4BT7A 3ZP4A 1VQKF 5C8YB 3PAFA 1VQLF 4X1KB 3HKCB 3P0ZA 3HKDB 3FFMA 2UYNB 3N2KB 3KE1A 2HX0A 5J2TB 1Q8RA 1ZWZA 5IJ9B 3D00A 2G9IA 3WJRA 2HS3A 3M4SA 3LWRC 3CC4F 1GX1A 2IG8A 2ZVZA 4O4JB 1YQNA 1VQ6F 3G4SF 1UFYA 2N48A 3LMEA 2GLZA 2AMTA 5FNVB 3F0DA 2BO1A 5HY1A 1W5FA 1X52A 3F0EA 4B46A 3NK7A 1VQ9F 3OBYA 5JCOA 4I50A 5HY4A 4ZI7A 3HKEA 3CMEF 1T0KB 5EZYA 2LCAA 3IKFA 2ZF8A 3HKEB 3RYIA 4B45A 5MN5A 5G4UC 3IKEA 3KJKA 3HKBB 5ITZA 1YITF 3I7TA 3OONA 5EWRA 1W40A 5HWEA 4F6RB 5EYPA 4X1YB 1J7HA 5JVDA 1JJ2F 4X1YA 1W3EX 3VTIC 1OFUA 5J2TA 1K8AH 4E6EA 3ERNA 3G6EF 3UT5B 4NUTA 1Q82H 3JALA 3KJJA 3ZOPA 1NMUB 5GONB 1JD1A 1QVFF 2PMPA 2HVYD 2P6YA 1PXWA 2UYPA 3RYCA 4WBNB 2FC3A 3KIZA 3U0OA 3CCMF 2AIZP 1E7KA 4YJ2B 3CB2A 3LDTA 4R40B 2QEXF 1S72F 3WJPA 3F6MA 4TUYA 4YJ3B 4G4WA 4YJ2A 5CB4B 1Q81H 4ZI7B 1JFFA 4B62A 5EB0A 1W55A 1R1MA 2CSLA 3VYUC 1M1KH 1RLUA 3J7AR 1SA0A 3NMUC 1FNJA 4M8IA 5MN4A 5EIBD 1FNKA 1FFXB 5IYZB 1GZ0A 3VYTC 1QD9A 1W2BF 1SA0B 1KNJA 2H8EA 4O4IB 3P10A 4RQOA 1KC8H 2VGNA 3VI6A 1RQ2A 3DDNA 5J2UA 4BVTA 3JATB 4G4XA 2YXZA 3JASB 3BYQA 2K1SA 2KGWA 3RYHB 2QA4F 2CW4A 5HP8A 3RE3A 3K12A 2LBWA 3CCSF 3JALB 4ZK7A 4NQ3A 1VQ7F 1IV3A 4O2BA 3HAXD 4LNUB 3MQWA 2HP0A 1VQVA
chains in the Genus database with same CATH topology
3HTNA 4BT6A 2HX0A 2H6LA 4BT4A 4BT5A 1XV2A 4BT2A 3HWUA 2P6YA 2NMUA 4BT3A 2DT4A 4BT7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HTN A;  4BT6 A;  2HX0 A;  2H6L A;  4BT4 A;  4BT5 A;  1XV2 A;  4BT2 A;  3HWU A;  2P6Y A;  2NMU A;  4BT3 A;  2DT4 A;  4BT7 A; 
#chains in the Genus database with same CATH topology
 1VQP F;  1COM A;  3CCJ F;  1XV2 A;  3B6N A;  4TV9 A;  4ZOL A;  1VH8 A;  3K14 A;  3VO8 A;  2ZOV A;  3VIU A;  1W5B A;  4BW0 B;  4O4L A;  3CC2 F;  3IEW A;  4EB6 B;  5JH7 A;  3WGN A;  3S02 A;  3HKB A;  2R75 1;  4U3J B;  2LBT A;  3OW2 F;  4I4T A;  3IMP A;  4C8G A;  3CCE F;  3LYB A;  4FFB A;  3ZP7 A;  2MQE A;  3CCV F;  3WJQ A;  3ON1 A;  3NVK E;  3I55 F;  1W41 A;  5KX5 B;  4KWE A;  1VQ5 F;  1DBF A;  3VMF B;  5G4V C;  1TUB B;  1W58 1;  3AGK A;  3CMA F;  4BT3 A;  1KNK A;  3FPI A;  2HP3 A;  5FNV A;  2Z01 A;  1XHO A;  4O4H A;  1PF5 A;  1TUB A;  4PWT A;  1KD1 H;  4ZOL B;  4C82 A;  3I56 F;  4I55 A;  3D54 A;  3WGJ A;  4BVQ A;  1VK3 A;  2VAM A;  3D01 A;  4O2B B;  5FLX M;  4TUY B;  3GHZ A;  4EI7 A;  4IHJ A;  3OBW A;  2HS0 A;  3ESJ A;  5CB4 A;  4G4Z A;  3PLA C;  4U3J A;  1YJ9 F;  3FBA A;  5A2Q M;  4X1K A;  4FFB B;  3CCQ F;  5IJ0 B;  2IQQ A;  2UYN A;  1W42 A;  3NVI B;  4ZHQ A;  1IV4 A;  5LOV B;  4EB6 A;  5C8Y A;  2HQS C;  2B33 A;  3N4Y A;  2V9Y A;  3N4Z A;  2DYY A;  3UT5 A;  1U40 A;  2H8C A;  4X3L A;  2ALE A;  4O2A A;  5IJ9 A;  5KMG B;  4ERH A;  4BT4 A;  3G71 F;  5EZY B;  1CK2 A;  5LXT A;  2OTM A;  4YJ3 A;  2Z1F A;  2KTU A;  3RYI B;  5LYJ B;  5HY0 A;  4U39 A;  2RHH A;  3T80 A;  5GAP K;  1GO0 A;  3V4D A;  3GTZ A;  1K73 H;  4I50 B;  3WXM B;  3K2X A;  3JAK B;  2EWC A;  1FFX A;  3QTY A;  1KQS F;  1TVK B;  4TV8 A;  5HXZ A;  4X1I A;  1VQ8 F;  5LA6 B;  3WGK A;  4ZHY B;  1ODE A;  4C81 A;  5LP6 C;  2UYJ A;  5JVD B;  1RQ7 A;  1GO1 A;  3O85 A;  2BTO A;  1X7P A;  3WPX A;  3NK6 A;  3M84 A;  3WPW A;  5KX5 A;  1VQN F;  2CWJ A;  3V7E A;  2FGY A;  3TD4 A;  2RHO A;  1OAP A;  2KG4 A;  2HRY A;  3IEQ A;  5LXT B;  3ELC A;  2BTQ B;  1W5A A;  2VAW A;  3DC2 A;  5GIP C;  2Q1X A;  2KTV A;  2YYE A;  1TVK A;  4X3M A;  2CZW A;  2LBX A;  3FD5 A;  3JAW A;  5B8F A;  2RHJ A;  2RB9 A;  4BVR A;  2I6D A;  1Z5V A;  1RA4 A;  5JQG A;  4F6R A;  3JAW B;  3LWQ C;  4G88 A;  2VGM A;  3C9T A;  3GYQ A;  3SIU A;  4BVS A;  1IV1 A;  4ZHQ B;  5LOV A;  1VQM F;  2RHL A;  3R0P A;  4C8I A;  2CVL A;  4C8E A;  5ITZ B;  1SDS A;  3CPQ A;  5GIO C;  3C8L A;  1T0A A;  1XBI A;  3J81 M;  1JN1 A;  3M1X A;  5HXU A;  5EAZ A;  3CD6 F;  1QAH A;  3VOA A;  3C9U A;  3LWO C;  1QU9 A;  4WBN A;  1SZQ A;  2Q1Y A;  3KHN A;  4ZHV A;  3CG6 A;  4DXD A;  2R6R 1;  3JAR B;  4NWO B;  3QHD A;  3JAM M;  1JFF B;  3JVH A;  3C9S A;  3VCZ A;  4IIJ A;  5HY2 A;  3HTN A;  4LCK A;  1W5E A;  5CA1 B;  2WAL A;  4DRX B;  3CXC F;  1NQ3 A;  4LNU A;  2GZL A;  1YHQ F;  2ZOD A;  5IT9 M;  2HP0 B;  3RYF B;  2QTP A;  1VQ4 F;  1X7O A;  3MCQ A;  1N8R H;  3CCL F;  5JH7 B;  5HP7 A;  1U43 A;  2Z1U A;  4B5C A;  3HKC A;  2CHT A;  5GAN K;  3HKD A;  2GVI A;  4G4V A;  3JAT A;  1QVG F;  3N2G A;  2UYK A;  3VOB A;  1IPA A;  1H48 A;  5GON A;  3HWU A;  3EOR A;  5JCO C;  5EB1 B;  1H47 A;  2OTJ F;  4BT6 A;  1K9M H;  4O4J A;  1DT9 A;  3LWV C;  3P4E A;  4BY9 D;  1FSZ A;  4C4W C;  3WGL A;  3F0G A;  1VQO F;  5LP6 B;  3S06 A;  3CPW F;  2ZVY A;  2F9Z C;  3MCA B;  1Q86 H;  3IR9 A;  2ZAU A;  4HNA B;  3F0F A;  4EI8 A;  1RLG A;  5LYJ A;  3L7Q A;  4IIJ B;  3C9R A;  3ZO8 A;  5CA1 A;  2QI2 A;  2VXY A;  3I3F A;  2AIF A;  2PHN A;  4I4T B;  4O4I A;  4HNA A;  3WGM A;  1IV2 A;  4X20 A;  2UZH A;  3RYF A;  3MBM A;  4X1I B;  3E22 B;  3JCM M;  1VHA A;  2H6L A;  3RA6 A;  5LA6 A;  3SIV A;  4O4L B;  5CA0 A;  5EYP B;  1JY8 A;  3E22 A;  2W8B C;  4RHA A;  1U3L A;  3V7Q A;  5CA0 B;  3N2G B;  1Z5W A;  1Q7Y H;  1YI2 F;  2CHS A;  3V3T A;  4BT2 A;  3E1Y A;  3JAS A;  3FD6 A;  5FJ4 C;  3CCR F;  4XCQ A;  3TD5 A;  3K0T A;  3RYC B;  1M90 H;  1YGY A;  3CYQ A;  4EI9 A;  4O2A B;  3CC7 F;  1CN7 A;  3LFO A;  5BMV A;  4I55 B;  5MN6 A;  3CCU F;  4DRX A;  2OTL F;  2HRU A;  4TV9 B;  4IHJ B;  5JQG B;  5EIB C;  2NMU A;  2BTU A;  5AVM A;  5EO3 A;  5IYZ A;  1U3P A;  4X20 B;  2DT4 A;  4ZHW A;  5IJ0 A;  4TZZ A;  1W57 A;  4BT5 A;  3S0W A;  3HJW C;  2I6R A;  3JAK A;  1UI9 A;  3RA5 A;  1X25 A;  1XRG A;  2OHW A;  3CYP B;  1H7M A;  3S0H A;  2OZB A;  5J2U B;  3N2K A;  2Z1T A;  3RYH A;  1W59 A;  2HS4 A;  3TD3 A;  3S03 A;  1ONI A;  1YJW F;  2Z1E A;  3Q8H A;  3S0Y A;  1CLI A;  4G4Y A;  3J80 M;  2VAP A;  2L26 A;  3JAR A;  4O4H B;  5DCV A;  1YIJ F;  3VYS C;  5LP6 A;  5KMG A;  3QUW A;  5GIN C;  2JNB A;  1NJI H;  2IAF A;  5BMV B;  3LWP C;  3E20 B;  1YJN F;  3MDO A;  4TV8 B;  4BT7 A;  3ZP4 A;  1VQK F;  5C8Y B;  3PAF A;  1VQL F;  4X1K B;  3HKC B;  3P0Z A;  3HKD B;  3FFM A;  2UYN B;  3N2K B;  3KE1 A;  2HX0 A;  5J2T B;  1Q8R A;  1ZWZ A;  5IJ9 B;  3D00 A;  2G9I A;  3WJR A;  2HS3 A;  3M4S A;  3LWR C;  3CC4 F;  1GX1 A;  2IG8 A;  2ZVZ A;  4O4J B;  1YQN A;  1VQ6 F;  3G4S F;  1UFY A;  2N48 A;  3LME A;  2GLZ A;  2AMT A;  5FNV B;  3F0D A;  2BO1 A;  5HY1 A;  1W5F A;  1X52 A;  3F0E A;  4B46 A;  3NK7 A;  1VQ9 F;  3OBY A;  5JCO A;  4I50 A;  5HY4 A;  4ZI7 A;  3HKE A;  3CME F;  1T0K B;  5EZY A;  2LCA A;  3IKF A;  2ZF8 A;  3HKE B;  3RYI A;  4B45 A;  5MN5 A;  5G4U C;  3IKE A;  3KJK A;  3HKB B;  5ITZ A;  1YIT F;  3I7T A;  3OON A;  5EWR A;  1W40 A;  5HWE A;  4F6R B;  5EYP A;  4X1Y B;  1J7H A;  5JVD A;  1JJ2 F;  4X1Y A;  1W3E X;  3VTI C;  1OFU A;  5J2T A;  1K8A H;  4E6E A;  3ERN A;  3G6E F;  3UT5 B;  4NUT A;  1Q82 H;  3JAL A;  3KJJ A;  3ZOP A;  1NMU B;  5GON B;  1JD1 A;  1QVF F;  2PMP A;  2HVY D;  2P6Y A;  1PXW A;  2UYP A;  3RYC A;  4WBN B;  2FC3 A;  3KIZ A;  3U0O A;  3CCM F;  2AIZ P;  1E7K A;  4YJ2 B;  3CB2 A;  3LDT A;  4R40 B;  2QEX F;  1S72 F;  3WJP A;  3F6M A;  4TUY A;  4YJ3 B;  4G4W A;  4YJ2 A;  5CB4 B;  1Q81 H;  4ZI7 B;  1JFF A;  4B62 A;  5EB0 A;  1W55 A;  1R1M A;  2CSL A;  3VYU C;  1M1K H;  1RLU A;  3J7A R;  1SA0 A;  3NMU C;  1FNJ A;  4M8I A;  5MN4 A;  5EIB D;  1FNK A;  1FFX B;  5IYZ B;  1GZ0 A;  3VYT C;  1QD9 A;  1W2B F;  1SA0 B;  1KNJ A;  2H8E A;  4O4I B;  3P10 A;  4RQO A;  1KC8 H;  2VGN A;  3VI6 A;  1RQ2 A;  3DDN A;  5J2U A;  4BVT A;  3JAT B;  4G4X A;  2YXZ A;  3JAS B;  3BYQ A;  2K1S A;  2KGW A;  3RYH B;  2QA4 F;  2CW4 A;  5HP8 A;  3RE3 A;  3K12 A;  2LBW A;  3CCS F;  3JAL B;  4ZK7 A;  4NQ3 A;  1VQ7 F;  1IV3 A;  4O2B A;  3HAX D;  4LNU B;  3MQW A;  2HP0 A;  1VQV A; 
#chains in the Genus database with same CATH homology
 3HTN A;  4BT6 A;  2HX0 A;  2H6L A;  4BT4 A;  4BT5 A;  1XV2 A;  4BT2 A;  3HWU A;  2P6Y A;  2NMU A;  4BT3 A;  2DT4 A;  4BT7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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