4BT2A

Acetolactate decarboxylase with a bound 1,2-ethanediol
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
237
structure length
237
Chain Sequence
APKNVLFQYSTINALMLGQFEGDLTLKDLKLRGDMGLGTINDLDGEMIQMGTKFYQIDSTGKLSELPESVKTPFAVTTHFEPKEKTTLTNVQDYNQLTKMLEEKFENKNVFYAVKLTGTFKMVKARTVPKQTRPYPQLTEVTKKQSEFEFKNVKGTLIGFYTPNYAAALNVPGFHLHFITEDKTSGGHVLNLQFDNANLEISPIHEFDVQLPHTDDFAHSDLTQVTTSQVHQAESER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and Mechanism of Acetolactate Decarboxylase
pubmed doi rcsb
molecule tags Lyase
source organism Brevibacillus brevis
molecule keywords ALPHA-ACETOLACTATE DECARBOXYLASE
total genus 74
structure length 237
sequence length 237
ec nomenclature ec 4.1.1.5: Acetolactate decarboxylase.
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03306 AAL_decarboxy Alpha-acetolactate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1330.80 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 4bt2A02
3.30.1330.80 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 4bt2A01
4BT7A 4BT4A 2H6LA 2DT4A 2P6YA 2HX0A 4BT5A 4BT2A 3HWUA 3HTNA 2NMUA 4BT3A 1XV2A 4BT6A
chains in the Genus database with same CATH superfamily
3KIZA 2JNBA 5JQGB 3HTNA 2UYJA 3ESJA 2VGMA 3MCAB 4BY9D 2CSLA 1UFYA 3RYFB 3HKDB 3S0HA 3E1YA 5EAZA 2GLZA 1E7KA 1W5AA 4IHJA 3QHDA 4O4LB 2LBTA 5DCVA 2IG8A 3S06A 3CCUF 4O4HB 4ZHQA 1K8AH 3WPWA 1CN7A 2CHSA 3WGNA 1XRGA 2UYPA 3IKFA 3P4EA 3JALA 4X20B 3RYHA 3J81M 4FFBA 1YIJF 3N2KB 1SDSA 4ZI7A 1YI2F 3M1XA 4BT4A 3VMFB 1OAPA 4O2BA 1GZ0A 1U3PA 3UT5A 3LWOC 3I56F 3RE3A 2OZBA 4NWOB 3KHNA 5BMVB 5IYZA 5EIBD 2VAPA 3I3FA 3PAFA 3VOAA 4TV8B 5IJ0B 2UZHA 2GVIA 1COMA 1N8RH 5EO3A 2Z1EA 4G4WA 2ZOVA 3F0FA 3CPWF 2IQQA 1IV4A 3G6EF 2QEXF 3CCQF 1DBFA 4C4WC 4YJ3A 5LP6A 3CC4F 3RA5A 2ALEA 2R6R1 3WGLA 5J2UA 4C81A 2DT4A 3GHZA 1K9MH 3WJPA 1XBIA 4B46A 4YJ2A 4IHJB 5LOVA 2YYEA 3HKEA 4WBNA 1RLUA 1VQNF 4ZHQB 3T80A 1PF5A 3WGMA 1T0KB 3WJRA 1KNJA 4RHAA 5KMGA 3JALB 3MDOA 2HP0A 2PHNA 5HXUA 4BVSA 3RYHB 2MQEA 5EZYA 4O4LA 4FFBB 5GONA 3LWPC 1Q8RA 1Z5WA 3GTZA 3N2GA 2QTPA 2Q1XA 1JJ2F 2I6DA 4R40B 4ZI7B 5HXZA 4O2BB 3UT5B 2HRYA 2OHWA 5IYZB 3IEWA 3P10A 1QAHA 3KJKA 2DYYA 4X20A 5HY0A 4X1IA 2OTLF 4PWTA 1FNJA 3KJJA 2Z1FA 4TUYA 2RHLA 4O4JA 3CB2A 1VQPF 3HJWC 2CW4A 2VAMA 3JAWA 1FFXA 1YGYA 2FGYA 4YJ3B 5LP6B 4I55A 1VQKF 2I6RA 3WPXA 5J2UB 1NQ3A 1TVKB 2KTUA 4G4ZA 3WJQA 3M84A 1X7OA 2ZAUA 4YJ2B 3RYIA 4BT5A 3JVHA 5LOVB 3JATA 2AIZP 1KC8H 3JARA 3HKEB 4EI8A 3SIUA 4WBNB 4XCQA 3V4DA 3LMEA 2QA4F 4U3JA 3NVKE 3NVIB 3NMUC 1U3LA 4EI7A 4C8EA 5EB1B 5KMGB 3HKBA 2LBXA 2ZODA 3OW2F 3E20B 2HP0B 1JFFA 5HP8A 1J7HA 1DT9A 3AGKA 5EZYB 5GONB 4ZOLA 2CZWA 2HQSC 1QVGF 3S02A 2HS0A 3N2GB 3D01A 2ZVZA 3ZP4A 5CB4A 4B5CA 5EWRA 2ZF8A 5IT9M 3OBWA 2R751 1RQ7A 3F0GA 1VHAA 4B62A 4HNAA 3CCJF 3V3TA 3P0ZA 1NMUB 4X1IB 5GAPK 1YITF 3ZO8A 3LYBA 1SA0A 3CPQA 4TUYB 1XV2A 2HP3A 4O4JB 2OTMA 3JAWB 1FFXB 4ZK7A 5FJ4C 2CVLA 4I55B 5ITZA 3D00A 4I4TA 3PLAC 1QD9A 3U0OA 4EB6A 3ON1A 2K1SA 4TV9A 3RYIB 4KWEA 1W42A 4U39A 3IKEA 3HWUA 4LNUA 3LWRC 3JATB 3GYQA 4X1YA 3CCLF 3JARB 1W59A 1VQVA 4X1KA 4BT7A 3OONA 2F9ZC 4U3JB 2Q1YA 3LDTA 5EIBC 3C8LA 1T0AA 1TVKA 1VQ5F 3HKBB 2N48A 2RHHA 3F0DA 4NQ3A 1JFFB 5CA1A 3ERNA 4ZOLB 5G4UC 2LBWA 3R0PA 5CB4B 5GIOC 4ERHA 2RB9A 1YHQF 4I50A 1M90H 3CCVF 4HNAB 1W40A 2HS4A 3K14A 4BT2A 5JH7A 3D54A 3G71F 1VQ4F 1JD1A 1SA0B 3CCMF 3CCRF 2G9IA 1RLGA 3IEQA 3NK7A 3I55F 5ITZB 4I4TB 3JAMM 3KE1A 3ELCA 4F6RA 4EB6B 2AIFA 3VO8A 4X3MA 4TV9B 3VIUA 1Q82H 1X52A 1VQ9F 4BVQA 4LNUB 1M1KH 1VQ7F 4X1YB 1YQNA 5HWEA 4EI9A 2RHJA 4X1KB 3CC7F 2KGWA 5B8FA 3CG6A 2HX0A 4O4IA 1Q86H 1OFUA 4O2AA 1ONIA 3O85A 3MCQA 5CA1B 2BO1A 1KQSF 3JASA 1U43A 4BT6A 3CXCF 1YJNF 2VGNA 1VQMF 1H47A 1TUBA 2BTUA 2RHOA 2CHTA 4G88A 3DDNA 1W581 1IPAA 4DRXA 5FNVA 4B45A 5C8YA 3WGKA 3JAKA 2BTOA 1Q81H 4I50B 4G4YA 3S0YA 1H7MA 3WGJA 4X3LA 1U40A 2Z1TA 2Z1UA 3VYSC 2OTJF 5HY1A 5JH7B 4ZHVA 1W57A 5GIPC 3K0TA 5JCOA 1KNKA 4BW0B 3SIVA 5LYJB 2BTQB 1VQ8F 1W55A 1W5EA 1X25A 1S72F 3K2XA 5HY4A 3MQWA 3CC2F 4G4XA 3CYPB 5HY2A 2W8BC 3RYCA 2Z01A 3DC2A 2HS3A 3MBMA 3IR9A 3CCSF 5MN4A 3C9SA 4F6RB 4M8IA 3C9RA 5LA6A 5A2QM 4IIJA 3FPIA 5JVDA 3J80M 3VOBA 3F6MA 2VXYA 5JCOC 3ZOPA 3IMPA 1JY8A 1W5BA 3N4ZA 3QTYA 4C8IA 4O4IB 1VK3A 2P6YA 3CD6F 3FFMA 4O2AB 3VYTC 3OBYA 3S0WA 3VYUC 1W2BF 1CK2A 1XHOA 1H48A 3JASB 4E6EA 1K73H 1TUBB 2H8EA 4DXDA 3K12A 4DRXB 3CMAF 1VH8A 5FNVB 3CCEF 5C8YB 3C9TA 3JAKB 4ZHWA 5KX5A 3N4YA 5CA0A 3RA6A 5EYPA 2YXZA 1RQ2A 3TD5A 1UI9A 3Q8HA 1KD1H 3NK6A 4ZHYB 5LXTA 1QU9A 3V7EA 3I7TA 1ZWZA 4TZZA 3HKCA 2UYKA 5HP7A 3RYCB 1JN1A 3L7QA 4C82A 2FC3A 5AVMA 2V9YA 3BYQA 1PXWA 3ZP7A 4BT3A 3J7AR 2WALA 5J2TA 1Z5VA 2UYNA 5LA6B 1YJWF 2QI2A 5MN6A 3S03A 4IIJB 5JVDB 5LYJA 2VAWA 5IJ9A 4RQOA 5GINC 3JCMM 3E22A 4NUTA 1IV1A 5JQGA 3LWQC 3V7QA 3VI6A 3FBAA 1W3EX 5G4VC 1IV2A 3HAXD 3CYQA 2EWCA 2H8CA 2HVYD 2AMTA 3RYFA 3HKDA 4BVRA 5LP6C 3EORA 4G4VA 2H6LA 2KG4A 1VQ6F 2CWJA 1GO0A 1W5FA 5KX5B 1X7PA 3VTIC 5EB0A 1W41A 4O4HA 1RA4A 5CA0B 4LCKA 1GO1A 3B6NA 5EYPB 1YJ9F 3WXMB 2ZVYA 2HRUA 3CMEF 1IV3A 1FSZA 3TD4A 2IAFA 3QUWA 1NJIH 1VQLF 3LWVC 2GZLA 2L26A 5GANK 2NMUA 2PMPA 3C9UA 4BVTA 5LXTB 5MN5A 3N2KA 1SZQA 1FNKA 2LCAA 1R1MA 1QVFF 3HKCB 3G4SF 3F0EA 2B33A 3LFOA 5FLXM 2KTVA 1ODEA 3FD5A 1CLIA 3VCZA 5BMVA 3FD6A 1GX1A 1VQOF 4TV8A 5J2TB 2UYNB 5IJ0A 3M4SA 5IJ9B 3TD3A 4C8GA 1Q7YH 3E22B
chains in the Genus database with same CATH topology
4BT7A 4BT4A 2H6LA 2DT4A 2P6YA 2HX0A 4BT5A 4BT2A 3HWUA 3HTNA 2NMUA 4BT3A 1XV2A 4BT6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BT7 A;  4BT4 A;  2H6L A;  2DT4 A;  2P6Y A;  2HX0 A;  4BT5 A;  4BT2 A;  3HWU A;  3HTN A;  2NMU A;  4BT3 A;  1XV2 A;  4BT6 A; 
#chains in the Genus database with same CATH topology
 3KIZ A;  2JNB A;  5JQG B;  3HTN A;  2UYJ A;  3ESJ A;  2VGM A;  3MCA B;  4BY9 D;  2CSL A;  1UFY A;  3RYF B;  3HKD B;  3S0H A;  3E1Y A;  5EAZ A;  2GLZ A;  1E7K A;  1W5A A;  4IHJ A;  3QHD A;  4O4L B;  2LBT A;  5DCV A;  2IG8 A;  3S06 A;  3CCU F;  4O4H B;  4ZHQ A;  1K8A H;  3WPW A;  1CN7 A;  2CHS A;  3WGN A;  1XRG A;  2UYP A;  3IKF A;  3P4E A;  3JAL A;  4X20 B;  3RYH A;  3J81 M;  4FFB A;  1YIJ F;  3N2K B;  1SDS A;  4ZI7 A;  1YI2 F;  3M1X A;  4BT4 A;  3VMF B;  1OAP A;  4O2B A;  1GZ0 A;  1U3P A;  3UT5 A;  3LWO C;  3I56 F;  3RE3 A;  2OZB A;  4NWO B;  3KHN A;  5BMV B;  5IYZ A;  5EIB D;  2VAP A;  3I3F A;  3PAF A;  3VOA A;  4TV8 B;  5IJ0 B;  2UZH A;  2GVI A;  1COM A;  1N8R H;  5EO3 A;  2Z1E A;  4G4W A;  2ZOV A;  3F0F A;  3CPW F;  2IQQ A;  1IV4 A;  3G6E F;  2QEX F;  3CCQ F;  1DBF A;  4C4W C;  4YJ3 A;  5LP6 A;  3CC4 F;  3RA5 A;  2ALE A;  2R6R 1;  3WGL A;  5J2U A;  4C81 A;  2DT4 A;  3GHZ A;  1K9M H;  3WJP A;  1XBI A;  4B46 A;  4YJ2 A;  4IHJ B;  5LOV A;  2YYE A;  3HKE A;  4WBN A;  1RLU A;  1VQN F;  4ZHQ B;  3T80 A;  1PF5 A;  3WGM A;  1T0K B;  3WJR A;  1KNJ A;  4RHA A;  5KMG A;  3JAL B;  3MDO A;  2HP0 A;  2PHN A;  5HXU A;  4BVS A;  3RYH B;  2MQE A;  5EZY A;  4O4L A;  4FFB B;  5GON A;  3LWP C;  1Q8R A;  1Z5W A;  3GTZ A;  3N2G A;  2QTP A;  2Q1X A;  1JJ2 F;  2I6D A;  4R40 B;  4ZI7 B;  5HXZ A;  4O2B B;  3UT5 B;  2HRY A;  2OHW A;  5IYZ B;  3IEW A;  3P10 A;  1QAH A;  3KJK A;  2DYY A;  4X20 A;  5HY0 A;  4X1I A;  2OTL F;  4PWT A;  1FNJ A;  3KJJ A;  2Z1F A;  4TUY A;  2RHL A;  4O4J A;  3CB2 A;  1VQP F;  3HJW C;  2CW4 A;  2VAM A;  3JAW A;  1FFX A;  1YGY A;  2FGY A;  4YJ3 B;  5LP6 B;  4I55 A;  1VQK F;  2I6R A;  3WPX A;  5J2U B;  1NQ3 A;  1TVK B;  2KTU A;  4G4Z A;  3WJQ A;  3M84 A;  1X7O A;  2ZAU A;  4YJ2 B;  3RYI A;  4BT5 A;  3JVH A;  5LOV B;  3JAT A;  2AIZ P;  1KC8 H;  3JAR A;  3HKE B;  4EI8 A;  3SIU A;  4WBN B;  4XCQ A;  3V4D A;  3LME A;  2QA4 F;  4U3J A;  3NVK E;  3NVI B;  3NMU C;  1U3L A;  4EI7 A;  4C8E A;  5EB1 B;  5KMG B;  3HKB A;  2LBX A;  2ZOD A;  3OW2 F;  3E20 B;  2HP0 B;  1JFF A;  5HP8 A;  1J7H A;  1DT9 A;  3AGK A;  5EZY B;  5GON B;  4ZOL A;  2CZW A;  2HQS C;  1QVG F;  3S02 A;  2HS0 A;  3N2G B;  3D01 A;  2ZVZ A;  3ZP4 A;  5CB4 A;  4B5C A;  5EWR A;  2ZF8 A;  5IT9 M;  3OBW A;  2R75 1;  1RQ7 A;  3F0G A;  1VHA A;  4B62 A;  4HNA A;  3CCJ F;  3V3T A;  3P0Z A;  1NMU B;  4X1I B;  5GAP K;  1YIT F;  3ZO8 A;  3LYB A;  1SA0 A;  3CPQ A;  4TUY B;  1XV2 A;  2HP3 A;  4O4J B;  2OTM A;  3JAW B;  1FFX B;  4ZK7 A;  5FJ4 C;  2CVL A;  4I55 B;  5ITZ A;  3D00 A;  4I4T A;  3PLA C;  1QD9 A;  3U0O A;  4EB6 A;  3ON1 A;  2K1S A;  4TV9 A;  3RYI B;  4KWE A;  1W42 A;  4U39 A;  3IKE A;  3HWU A;  4LNU A;  3LWR C;  3JAT B;  3GYQ A;  4X1Y A;  3CCL F;  3JAR B;  1W59 A;  1VQV A;  4X1K A;  4BT7 A;  3OON A;  2F9Z C;  4U3J B;  2Q1Y A;  3LDT A;  5EIB C;  3C8L A;  1T0A A;  1TVK A;  1VQ5 F;  3HKB B;  2N48 A;  2RHH A;  3F0D A;  4NQ3 A;  1JFF B;  5CA1 A;  3ERN A;  4ZOL B;  5G4U C;  2LBW A;  3R0P A;  5CB4 B;  5GIO C;  4ERH A;  2RB9 A;  1YHQ F;  4I50 A;  1M90 H;  3CCV F;  4HNA B;  1W40 A;  2HS4 A;  3K14 A;  4BT2 A;  5JH7 A;  3D54 A;  3G71 F;  1VQ4 F;  1JD1 A;  1SA0 B;  3CCM F;  3CCR F;  2G9I A;  1RLG A;  3IEQ A;  3NK7 A;  3I55 F;  5ITZ B;  4I4T B;  3JAM M;  3KE1 A;  3ELC A;  4F6R A;  4EB6 B;  2AIF A;  3VO8 A;  4X3M A;  4TV9 B;  3VIU A;  1Q82 H;  1X52 A;  1VQ9 F;  4BVQ A;  4LNU B;  1M1K H;  1VQ7 F;  4X1Y B;  1YQN A;  5HWE A;  4EI9 A;  2RHJ A;  4X1K B;  3CC7 F;  2KGW A;  5B8F A;  3CG6 A;  2HX0 A;  4O4I A;  1Q86 H;  1OFU A;  4O2A A;  1ONI A;  3O85 A;  3MCQ A;  5CA1 B;  2BO1 A;  1KQS F;  3JAS A;  1U43 A;  4BT6 A;  3CXC F;  1YJN F;  2VGN A;  1VQM F;  1H47 A;  1TUB A;  2BTU A;  2RHO A;  2CHT A;  4G88 A;  3DDN A;  1W58 1;  1IPA A;  4DRX A;  5FNV A;  4B45 A;  5C8Y A;  3WGK A;  3JAK A;  2BTO A;  1Q81 H;  4I50 B;  4G4Y A;  3S0Y A;  1H7M A;  3WGJ A;  4X3L A;  1U40 A;  2Z1T A;  2Z1U A;  3VYS C;  2OTJ F;  5HY1 A;  5JH7 B;  4ZHV A;  1W57 A;  5GIP C;  3K0T A;  5JCO A;  1KNK A;  4BW0 B;  3SIV A;  5LYJ B;  2BTQ B;  1VQ8 F;  1W55 A;  1W5E A;  1X25 A;  1S72 F;  3K2X A;  5HY4 A;  3MQW A;  3CC2 F;  4G4X A;  3CYP B;  5HY2 A;  2W8B C;  3RYC A;  2Z01 A;  3DC2 A;  2HS3 A;  3MBM A;  3IR9 A;  3CCS F;  5MN4 A;  3C9S A;  4F6R B;  4M8I A;  3C9R A;  5LA6 A;  5A2Q M;  4IIJ A;  3FPI A;  5JVD A;  3J80 M;  3VOB A;  3F6M A;  2VXY A;  5JCO C;  3ZOP A;  3IMP A;  1JY8 A;  1W5B A;  3N4Z A;  3QTY A;  4C8I A;  4O4I B;  1VK3 A;  2P6Y A;  3CD6 F;  3FFM A;  4O2A B;  3VYT C;  3OBY A;  3S0W A;  3VYU C;  1W2B F;  1CK2 A;  1XHO A;  1H48 A;  3JAS B;  4E6E A;  1K73 H;  1TUB B;  2H8E A;  4DXD A;  3K12 A;  4DRX B;  3CMA F;  1VH8 A;  5FNV B;  3CCE F;  5C8Y B;  3C9T A;  3JAK B;  4ZHW A;  5KX5 A;  3N4Y A;  5CA0 A;  3RA6 A;  5EYP A;  2YXZ A;  1RQ2 A;  3TD5 A;  1UI9 A;  3Q8H A;  1KD1 H;  3NK6 A;  4ZHY B;  5LXT A;  1QU9 A;  3V7E A;  3I7T A;  1ZWZ A;  4TZZ A;  3HKC A;  2UYK A;  5HP7 A;  3RYC B;  1JN1 A;  3L7Q A;  4C82 A;  2FC3 A;  5AVM A;  2V9Y A;  3BYQ A;  1PXW A;  3ZP7 A;  4BT3 A;  3J7A R;  2WAL A;  5J2T A;  1Z5V A;  2UYN A;  5LA6 B;  1YJW F;  2QI2 A;  5MN6 A;  3S03 A;  4IIJ B;  5JVD B;  5LYJ A;  2VAW A;  5IJ9 A;  4RQO A;  5GIN C;  3JCM M;  3E22 A;  4NUT A;  1IV1 A;  5JQG A;  3LWQ C;  3V7Q A;  3VI6 A;  3FBA A;  1W3E X;  5G4V C;  1IV2 A;  3HAX D;  3CYQ A;  2EWC A;  2H8C A;  2HVY D;  2AMT A;  3RYF A;  3HKD A;  4BVR A;  5LP6 C;  3EOR A;  4G4V A;  2H6L A;  2KG4 A;  1VQ6 F;  2CWJ A;  1GO0 A;  1W5F A;  5KX5 B;  1X7P A;  3VTI C;  5EB0 A;  1W41 A;  4O4H A;  1RA4 A;  5CA0 B;  4LCK A;  1GO1 A;  3B6N A;  5EYP B;  1YJ9 F;  3WXM B;  2ZVY A;  2HRU A;  3CME F;  1IV3 A;  1FSZ A;  3TD4 A;  2IAF A;  3QUW A;  1NJI H;  1VQL F;  3LWV C;  2GZL A;  2L26 A;  5GAN K;  2NMU A;  2PMP A;  3C9U A;  4BVT A;  5LXT B;  5MN5 A;  3N2K A;  1SZQ A;  1FNK A;  2LCA A;  1R1M A;  1QVF F;  3HKC B;  3G4S F;  3F0E A;  2B33 A;  3LFO A;  5FLX M;  2KTV A;  1ODE A;  3FD5 A;  1CLI A;  3VCZ A;  5BMV A;  3FD6 A;  1GX1 A;  1VQO F;  4TV8 A;  5J2T B;  2UYN B;  5IJ0 A;  3M4S A;  5IJ9 B;  3TD3 A;  4C8G A;  1Q7Y H;  3E22 B; 
#chains in the Genus database with same CATH homology
 4BT7 A;  4BT4 A;  2H6L A;  2DT4 A;  2P6Y A;  2HX0 A;  4BT5 A;  4BT2 A;  3HWU A;  3HTN A;  2NMU A;  4BT3 A;  1XV2 A;  4BT6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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