4BT2A

Acetolactate decarboxylase with a bound 1,2-ethanediol
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
237
structure length
237
Chain Sequence
APKNVLFQYSTINALMLGQFEGDLTLKDLKLRGDMGLGTINDLDGEMIQMGTKFYQIDSTGKLSELPESVKTPFAVTTHFEPKEKTTLTNVQDYNQLTKMLEEKFENKNVFYAVKLTGTFKMVKARTVPKQTRPYPQLTEVTKKQSEFEFKNVKGTLIGFYTPNYAAALNVPGFHLHFITEDKTSGGHVLNLQFDNANLEISPIHEFDVQLPHTDDFAHSDLTQVTTSQVHQAESER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and Mechanism of Acetolactate Decarboxylase
pubmed doi rcsb
molecule tags Lyase
source organism Brevibacillus brevis
molecule keywords ALPHA-ACETOLACTATE DECARBOXYLASE
total genus 74
structure length 237
sequence length 237
ec nomenclature ec 4.1.1.5: Acetolactate decarboxylase.
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03306 AAL_decarboxy Alpha-acetolactate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1330.80 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 4bt2A02
3.30.1330.80 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 4bt2A01
3HTNA 4BT2A 2HX0A 2H6LA 4BT3A 4BT4A 4BT7A 2NMUA 2DT4A 1XV2A 2P6YA 4BT5A 4BT6A 3HWUA
chains in the Genus database with same CATH superfamily
4IIJB 1VQOF 4BVRA 3CPWF 4XCQA 2ZOVA 4U3JB 2OHWA 5C8YB 4FFBB 3BYQA 1N8RH 3E22B 3CCUF 2I6DA 3IKEA 1VQMF 3EORA 3VYTC 1IV1A 5ITZA 3JAWB 1KC8H 3K14A 3CC4F 1Q82H 4BVTA 4EI8A 3ZP4A 3G71F 4LNUB 1S72F 4C8EA 3JALA 2HP0A 2RHJA 3RA6A 5LP6A 3CXCF 3IR9A 4BT2A 4RHAA 1K8AH 5EZYB 3LWQC 4TZZA 2QA4F 2AIZP 1YJNF 3V7QA 5LA6B 1VQ4F 3HKDA 4O4JA 2CSLA 2PHNA 3VI6A 5FJ4C 3QTYA 1X52A 3S0WA 1IPAA 4X1KA 3V7EA 3CYPB 2RHHA 4NQ3A 1VQKF 3T80A 3WJQA 5J2UB 2KG4A 3FBAA 2R6R1 1TVKA 2DYYA 2N48A 2UZHA 5HXZA 3HKCA 3S02A 3S0YA 3D01A 1JFFB 2OZBA 2FGYA 2QI2A 3DC2A 3TD4A 4EB6B 1VQVA 1PF5A 3F0GA 2LBTA 3LFOA 3ZO8A 5HXUA 2LCAA 4I4TB 1XRGA 4M8IA 5CA1B 1PXWA 2CWJA 5EYPB 3KJKA 4O4IB 2LBXA 5GIOC 4DRXA 4ZHVA 4U3JA 5C8YA 4FFBA 3CCRF 3E22A 5IJ0A 1XV2A 4YJ2B 5BMVA 4TV8A 4YJ3A 2PMPA 1KNKA 3CCJF 2UYJA 3E1YA 1FFXA 3JAWA 2OTMA 2GVIA 2RHOA 2K1SA 2FC3A 3D54A 2GLZA 4LNUA 4F6RA 4G4ZA 4BY9D 2QTPA 3N4ZA 2HP0B 1VH8A 2UYPA 3CCSF 5GAPK 4PWTA 1QU9A 3KE1A 3CCVF 3VYSC 1U40A 3LWPC 3SIVA 3OONA 5LA6A 3NMUC 2L26A 2BTQB 2W8BC 3N4YA 3I56F 2ZAUA 2VAWA 1IV3A 5J2TB 3CYQA 1OAPA 5JVDA 4X1KB 5HP8A 3F0FA 3JATB 1T0AA 3GYQA 1JJ2F 4X20A 3NK7A 4C81A 5HY1A 5IYZA 3PLAC 3NK6A 3SIUA 3G4SF 4I55B 4C8IA 3KIZA 3M84A 3RYFB 3HKCB 5IT9M 3WJPA 3VOAA 5JCOC 4B46A 3MQWA 4EB6A 3LWOC 4ZOLB 1H7MA 3JARA 3HAXD 3ON1A 3ZP7A 1VQ5F 3C9TA 1M90H 1K9MH 3L7QA 1T0KB 4O4IA 3CMEF 4ZHQB 4DRXB 1W40A 3DDNA 4TUYB 1KNJA 3J7AR 4YJ2A 4G4VA 5IJ0B 5BMVB 1VQPF 4TV8B 3VYUC 4YJ3B 2JNBA 3S06A 3TD5A 3D00A 1CK2A 4TV9A 1FFXB 3LWRC 5A2QM 4O2BA 5MN5A 3CCQF 2ALEA 3OBWA 4F6RB 5FNVB 4G4WA 5MN6A 5JCOA 4ERHA 3WGMA 3J81M 1QAHA 1TUBB 1K73H 3RA5A 3WGNA 2Q1YA 1E7KA 3CD6F 3OBYA 2Z01A 3CC2F 2CVLA 5J2TA 2AIFA 1CN7A 1M1KH 3GTZA 1GX1A 3CC7F 2HRUA 3LWVC 5JVDB 3JATA 4X1IA 1VHAA 2Z1TA 3ELCA 4X20B 5GONA 3JAKB 3CCMF 5IYZB 4I55A 2HQSC 3RYFA 1Q86H 1VQLF 1KD1H 2V9YA 3WJRA 4ZOLA 3WGKA 3S0HA 1RA4A 2KTUA 4O4LA 5EWRA 2UYKA 2KGWA 4NWOB 2DT4A 2VGMA 3JARB 3UT5B 1W3EX 5EO3A 4ZHQA 2VGNA 2IAFA 1X7OA 3P0ZA 4BT5A 3IKFA 4RQOA 4TUYA 5EAZA 1NJIH 3JCMM 2KTVA 3PAFA 4X1YA 5LYJB 2VAPA 1H47A 3Q8HA 5MN4A 1GO0A 3U0OA 3VMFB 4TV9B 4O2BB 2H6LA 5FNVA 4BT7A 3E20B 1YQNA 1JD1A 1W5EA 2R751 4IHJB 3C9UA 1TUBA 3F6MA 5EIBD 4BVSA 4C8GA 2EWCA 1ZWZA 1RLGA 2MQEA 3VCZA 3C8LA 3QUWA 2HX0A 3CCLF 1SA0B 1Q8RA 5KX5A 4G88A 1Z5VA 2VXYA 4X1IB 3JAKA 1YGYA 1KQSF 1YITF 5GONB 3RYHB 3K0TA 4BT4A 1RQ2A 5CA0B 3C9SA 3WXMB 4EI9A 3HKBA 1Q81H 3VOBA 5FLXM 1QVFF 2Z1UA 4BVQA 5HY0A 3ERNA 3N2KA 5HP7A 3G6EF 1RQ7A 1QD9A 5JQGA 1W5AA 5HY4A 4O4LB 2UYNB 1W581 3UT5A 3RE3A 5B8FA 2ZVZA 2H8EA 1VQ9F 2HP3A 1W57A 3N2GA 1YHQF 5HY2A 3B6NA 3VO8A 1VK3A 2ZF8A 4I50B 1H48A 3LYBA 3ESJA 3IMPA 3CCEF 2RHLA 3HKEA 3CPQA 4EI7A 5LXTA 1W42A 1JN1A 5LYJA 3M4SA 4X1YB 1GO1A 1IV2A 1W55A 4WBNA 3CB2A 3FD5A 3CG6A 3I3FA 2GZLA 5DCVA 2CW4A 2AMTA 3C9RA 3HJWC 4IHJA 2YXZA 4U39A 3P4EA 1COMA 1SZQA 1NMUB 2BTOA 2I6RA 1XBIA 1W59A 2NMUA 3R0PA 1R1MA 2VAMA 1FNKA 5JH7B 3V3TA 1SA0A 2Z1FA 5HWEA 1JY8A 5CB4B 4ZHYB 3FFMA 5KX5B 2IG8A 3TD3A 1ONIA 3I55F 2YYEA 3RYIA 4BT3A 3RYHA 5CA0A 1U43A 5IJ9B 3LDTA 4KWEA 1UFYA 3IEWA 2CHSA 4X3MA 3HKBB 2CZWA 1Q7YH 3K12A 1RLUA 4HNAA 5LOVA 4DXDA 3JASB 1DBFA 2Q1XA 3WGLA 2F9ZC 3HWUA 4ZI7B 3N2KB 2OTJF 4O4HB 2HS0A 5JQGB 3LMEA 2UYNA 1ODEA 5KMGA 3VTIC 1FSZA 4B5CA 4B62A 2B33A 1X7PA 3RYCB 3N2GB 1UI9A 1W5BA 5EB0A 4I50A 3J80M 5GINC 1SDSA 2HS4A 1CLIA 3HKEB 4ZK7A 1VQ7F 3VIUA 5LXTB 2LBWA 3QHDA 4O2AA 3F0DA 3FD6A 5AVMA 2G9IA 4WBNB 5GANK 3KJJA 4E6EA 2IQQA 4LCKA 3FPIA 4IIJA 3P10A 3IEQA 4BW0B 4G4XA 2WALA 3MCAB 3JAMM 3O85A 2H8CA 4C4WC 1Z5WA 4NUTA 5JH7A 2HS3A 1VQNF 3NVIB 3ZOPA 1QVGF 4R40B 5CB4A 1J7HA 1VQ8F 4X3LA 5ITZB 3S03A 2RB9A 2P6YA 2ZVYA 3AGKA 5EIBC 4BT6A 1IV4A 2HVYD 2CHTA 2HRYA 1YJWF 3RYIB 3JALB 3M1XA 5IJ9A 5GIPC 1U3PA 1OFUA 5G4VC 1XHOA 4C82A 5LP6B 1X25A 5EZYA 3MCQA 5G4UC 3GHZA 3K2XA 3JASA 4HNAB 5LOVB 1W41A 1YJ9F 1U3LA 4ZI7A 4O4HA 3HKDB 3NVKE 4O4JB 1YIJF 4G4YA 3JVHA 5KMGB 3I7TA 1YI2F 2OTLF 2Z1EA 1GZ0A 1W5FA 3RYCA 3V4DA 5J2UA 3F0EA 2BTUA 3WPWA 1TVKB 3KHNA 3WGJA 2QEXF 4B45A 3HTNA 1JFFA 1FNJA 3CMAF 5EB1B 4O2AB 5LP6C 3MBMA 2BO1A 2ZODA 3MDOA 3OW2F 4I4TA 1NQ3A 4ZHWA 1W2BF 5CA1A 1VQ6F 3WPXA 1DT9A 5EYPA
chains in the Genus database with same CATH topology
3HTNA 4BT2A 2HX0A 2H6LA 4BT3A 4BT4A 4BT7A 2NMUA 2DT4A 1XV2A 2P6YA 4BT5A 4BT6A 3HWUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HTN A;  4BT2 A;  2HX0 A;  2H6L A;  4BT3 A;  4BT4 A;  4BT7 A;  2NMU A;  2DT4 A;  1XV2 A;  2P6Y A;  4BT5 A;  4BT6 A;  3HWU A; 
#chains in the Genus database with same CATH topology
 4IIJ B;  1VQO F;  4BVR A;  3CPW F;  4XCQ A;  2ZOV A;  4U3J B;  2OHW A;  5C8Y B;  4FFB B;  3BYQ A;  1N8R H;  3E22 B;  3CCU F;  2I6D A;  3IKE A;  1VQM F;  3EOR A;  3VYT C;  1IV1 A;  5ITZ A;  3JAW B;  1KC8 H;  3K14 A;  3CC4 F;  1Q82 H;  4BVT A;  4EI8 A;  3ZP4 A;  3G71 F;  4LNU B;  1S72 F;  4C8E A;  3JAL A;  2HP0 A;  2RHJ A;  3RA6 A;  5LP6 A;  3CXC F;  3IR9 A;  4BT2 A;  4RHA A;  1K8A H;  5EZY B;  3LWQ C;  4TZZ A;  2QA4 F;  2AIZ P;  1YJN F;  3V7Q A;  5LA6 B;  1VQ4 F;  3HKD A;  4O4J A;  2CSL A;  2PHN A;  3VI6 A;  5FJ4 C;  3QTY A;  1X52 A;  3S0W A;  1IPA A;  4X1K A;  3V7E A;  3CYP B;  2RHH A;  4NQ3 A;  1VQK F;  3T80 A;  3WJQ A;  5J2U B;  2KG4 A;  3FBA A;  2R6R 1;  1TVK A;  2DYY A;  2N48 A;  2UZH A;  5HXZ A;  3HKC A;  3S02 A;  3S0Y A;  3D01 A;  1JFF B;  2OZB A;  2FGY A;  2QI2 A;  3DC2 A;  3TD4 A;  4EB6 B;  1VQV A;  1PF5 A;  3F0G A;  2LBT A;  3LFO A;  3ZO8 A;  5HXU A;  2LCA A;  4I4T B;  1XRG A;  4M8I A;  5CA1 B;  1PXW A;  2CWJ A;  5EYP B;  3KJK A;  4O4I B;  2LBX A;  5GIO C;  4DRX A;  4ZHV A;  4U3J A;  5C8Y A;  4FFB A;  3CCR F;  3E22 A;  5IJ0 A;  1XV2 A;  4YJ2 B;  5BMV A;  4TV8 A;  4YJ3 A;  2PMP A;  1KNK A;  3CCJ F;  2UYJ A;  3E1Y A;  1FFX A;  3JAW A;  2OTM A;  2GVI A;  2RHO A;  2K1S A;  2FC3 A;  3D54 A;  2GLZ A;  4LNU A;  4F6R A;  4G4Z A;  4BY9 D;  2QTP A;  3N4Z A;  2HP0 B;  1VH8 A;  2UYP A;  3CCS F;  5GAP K;  4PWT A;  1QU9 A;  3KE1 A;  3CCV F;  3VYS C;  1U40 A;  3LWP C;  3SIV A;  3OON A;  5LA6 A;  3NMU C;  2L26 A;  2BTQ B;  2W8B C;  3N4Y A;  3I56 F;  2ZAU A;  2VAW A;  1IV3 A;  5J2T B;  3CYQ A;  1OAP A;  5JVD A;  4X1K B;  5HP8 A;  3F0F A;  3JAT B;  1T0A A;  3GYQ A;  1JJ2 F;  4X20 A;  3NK7 A;  4C81 A;  5HY1 A;  5IYZ A;  3PLA C;  3NK6 A;  3SIU A;  3G4S F;  4I55 B;  4C8I A;  3KIZ A;  3M84 A;  3RYF B;  3HKC B;  5IT9 M;  3WJP A;  3VOA A;  5JCO C;  4B46 A;  3MQW A;  4EB6 A;  3LWO C;  4ZOL B;  1H7M A;  3JAR A;  3HAX D;  3ON1 A;  3ZP7 A;  1VQ5 F;  3C9T A;  1M90 H;  1K9M H;  3L7Q A;  1T0K B;  4O4I A;  3CME F;  4ZHQ B;  4DRX B;  1W40 A;  3DDN A;  4TUY B;  1KNJ A;  3J7A R;  4YJ2 A;  4G4V A;  5IJ0 B;  5BMV B;  1VQP F;  4TV8 B;  3VYU C;  4YJ3 B;  2JNB A;  3S06 A;  3TD5 A;  3D00 A;  1CK2 A;  4TV9 A;  1FFX B;  3LWR C;  5A2Q M;  4O2B A;  5MN5 A;  3CCQ F;  2ALE A;  3OBW A;  4F6R B;  5FNV B;  4G4W A;  5MN6 A;  5JCO A;  4ERH A;  3WGM A;  3J81 M;  1QAH A;  1TUB B;  1K73 H;  3RA5 A;  3WGN A;  2Q1Y A;  1E7K A;  3CD6 F;  3OBY A;  2Z01 A;  3CC2 F;  2CVL A;  5J2T A;  2AIF A;  1CN7 A;  1M1K H;  3GTZ A;  1GX1 A;  3CC7 F;  2HRU A;  3LWV C;  5JVD B;  3JAT A;  4X1I A;  1VHA A;  2Z1T A;  3ELC A;  4X20 B;  5GON A;  3JAK B;  3CCM F;  5IYZ B;  4I55 A;  2HQS C;  3RYF A;  1Q86 H;  1VQL F;  1KD1 H;  2V9Y A;  3WJR A;  4ZOL A;  3WGK A;  3S0H A;  1RA4 A;  2KTU A;  4O4L A;  5EWR A;  2UYK A;  2KGW A;  4NWO B;  2DT4 A;  2VGM A;  3JAR B;  3UT5 B;  1W3E X;  5EO3 A;  4ZHQ A;  2VGN A;  2IAF A;  1X7O A;  3P0Z A;  4BT5 A;  3IKF A;  4RQO A;  4TUY A;  5EAZ A;  1NJI H;  3JCM M;  2KTV A;  3PAF A;  4X1Y A;  5LYJ B;  2VAP A;  1H47 A;  3Q8H A;  5MN4 A;  1GO0 A;  3U0O A;  3VMF B;  4TV9 B;  4O2B B;  2H6L A;  5FNV A;  4BT7 A;  3E20 B;  1YQN A;  1JD1 A;  1W5E A;  2R75 1;  4IHJ B;  3C9U A;  1TUB A;  3F6M A;  5EIB D;  4BVS A;  4C8G A;  2EWC A;  1ZWZ A;  1RLG A;  2MQE A;  3VCZ A;  3C8L A;  3QUW A;  2HX0 A;  3CCL F;  1SA0 B;  1Q8R A;  5KX5 A;  4G88 A;  1Z5V A;  2VXY A;  4X1I B;  3JAK A;  1YGY A;  1KQS F;  1YIT F;  5GON B;  3RYH B;  3K0T A;  4BT4 A;  1RQ2 A;  5CA0 B;  3C9S A;  3WXM B;  4EI9 A;  3HKB A;  1Q81 H;  3VOB A;  5FLX M;  1QVF F;  2Z1U A;  4BVQ A;  5HY0 A;  3ERN A;  3N2K A;  5HP7 A;  3G6E F;  1RQ7 A;  1QD9 A;  5JQG A;  1W5A A;  5HY4 A;  4O4L B;  2UYN B;  1W58 1;  3UT5 A;  3RE3 A;  5B8F A;  2ZVZ A;  2H8E A;  1VQ9 F;  2HP3 A;  1W57 A;  3N2G A;  1YHQ F;  5HY2 A;  3B6N A;  3VO8 A;  1VK3 A;  2ZF8 A;  4I50 B;  1H48 A;  3LYB A;  3ESJ A;  3IMP A;  3CCE F;  2RHL A;  3HKE A;  3CPQ A;  4EI7 A;  5LXT A;  1W42 A;  1JN1 A;  5LYJ A;  3M4S A;  4X1Y B;  1GO1 A;  1IV2 A;  1W55 A;  4WBN A;  3CB2 A;  3FD5 A;  3CG6 A;  3I3F A;  2GZL A;  5DCV A;  2CW4 A;  2AMT A;  3C9R A;  3HJW C;  4IHJ A;  2YXZ A;  4U39 A;  3P4E A;  1COM A;  1SZQ A;  1NMU B;  2BTO A;  2I6R A;  1XBI A;  1W59 A;  2NMU A;  3R0P A;  1R1M A;  2VAM A;  1FNK A;  5JH7 B;  3V3T A;  1SA0 A;  2Z1F A;  5HWE A;  1JY8 A;  5CB4 B;  4ZHY B;  3FFM A;  5KX5 B;  2IG8 A;  3TD3 A;  1ONI A;  3I55 F;  2YYE A;  3RYI A;  4BT3 A;  3RYH A;  5CA0 A;  1U43 A;  5IJ9 B;  3LDT A;  4KWE A;  1UFY A;  3IEW A;  2CHS A;  4X3M A;  3HKB B;  2CZW A;  1Q7Y H;  3K12 A;  1RLU A;  4HNA A;  5LOV A;  4DXD A;  3JAS B;  1DBF A;  2Q1X A;  3WGL A;  2F9Z C;  3HWU A;  4ZI7 B;  3N2K B;  2OTJ F;  4O4H B;  2HS0 A;  5JQG B;  3LME A;  2UYN A;  1ODE A;  5KMG A;  3VTI C;  1FSZ A;  4B5C A;  4B62 A;  2B33 A;  1X7P A;  3RYC B;  3N2G B;  1UI9 A;  1W5B A;  5EB0 A;  4I50 A;  3J80 M;  5GIN C;  1SDS A;  2HS4 A;  1CLI A;  3HKE B;  4ZK7 A;  1VQ7 F;  3VIU A;  5LXT B;  2LBW A;  3QHD A;  4O2A A;  3F0D A;  3FD6 A;  5AVM A;  2G9I A;  4WBN B;  5GAN K;  3KJJ A;  4E6E A;  2IQQ A;  4LCK A;  3FPI A;  4IIJ A;  3P10 A;  3IEQ A;  4BW0 B;  4G4X A;  2WAL A;  3MCA B;  3JAM M;  3O85 A;  2H8C A;  4C4W C;  1Z5W A;  4NUT A;  5JH7 A;  2HS3 A;  1VQN F;  3NVI B;  3ZOP A;  1QVG F;  4R40 B;  5CB4 A;  1J7H A;  1VQ8 F;  4X3L A;  5ITZ B;  3S03 A;  2RB9 A;  2P6Y A;  2ZVY A;  3AGK A;  5EIB C;  4BT6 A;  1IV4 A;  2HVY D;  2CHT A;  2HRY A;  1YJW F;  3RYI B;  3JAL B;  3M1X A;  5IJ9 A;  5GIP C;  1U3P A;  1OFU A;  5G4V C;  1XHO A;  4C82 A;  5LP6 B;  1X25 A;  5EZY A;  3MCQ A;  5G4U C;  3GHZ A;  3K2X A;  3JAS A;  4HNA B;  5LOV B;  1W41 A;  1YJ9 F;  1U3L A;  4ZI7 A;  4O4H A;  3HKD B;  3NVK E;  4O4J B;  1YIJ F;  4G4Y A;  3JVH A;  5KMG B;  3I7T A;  1YI2 F;  2OTL F;  2Z1E A;  1GZ0 A;  1W5F A;  3RYC A;  3V4D A;  5J2U A;  3F0E A;  2BTU A;  3WPW A;  1TVK B;  3KHN A;  3WGJ A;  2QEX F;  4B45 A;  3HTN A;  1JFF A;  1FNJ A;  3CMA F;  5EB1 B;  4O2A B;  5LP6 C;  3MBM A;  2BO1 A;  2ZOD A;  3MDO A;  3OW2 F;  4I4T A;  1NQ3 A;  4ZHW A;  1W2B F;  5CA1 A;  1VQ6 F;  3WPX A;  1DT9 A;  5EYP A; 
#chains in the Genus database with same CATH homology
 3HTN A;  4BT2 A;  2HX0 A;  2H6L A;  4BT3 A;  4BT4 A;  4BT7 A;  2NMU A;  2DT4 A;  1XV2 A;  2P6Y A;  4BT5 A;  4BT6 A;  3HWU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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