1AWEA

Human sos1 pleckstrin homology (ph) domain, nmr, 20 structures
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
130
structure length
130
Chain Sequence
MNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains.
pubmed doi rcsb
molecule tags Signal transduction
source organism Homo sapiens
molecule keywords SOS1
total genus 17
structure length 130
sequence length 130
ec nomenclature
pdb deposition date 1997-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1aweA00
1ZM0A 1WGUA 2JP2A 1BTKA 1BAKA 1AWEA 5C6RA 2Q13A 4ZRJA 4B6HA 3D8EA 1SHCA 2D9ZA 1WVHA 3A8PA 5D3XA 1V89A 5GOWB 4GMVA 3G9WA 1UNRA 4HAYB 1Z87A 4WSFA 4Y94A 1UEFA 1QC6A 3SYXA 2XQNM 1XCGA 2CRFA 4HHVA 3T06A 1KI1B 2COAA 2D10A 2IYBA 3PG7A 1FAOA 1XKEA 3TW1A 3ULCA 2J0KA 4CYEA 4GZUA 4K2OA 2YF0A 3PEGA 4GN1A 1LW3A 1QQGA 5DIFB 1W1GA 3HW2B 1Y5OA 4DXAB 1EF1A 2DTCA 3SNHA 1MK7B 3CXBB 1X11A 4Z2NA 5DHAB 4KHOA 4YL8A 3TO1A 3PP2A 1EVHA 3DXEA 3PZDA 2M14A 1ZC4B 2H7DA 1DROA 2YRYA 2K00A 3A8QA 2EJ8A 1GC7A 4IOYX 1BTNA 3ODOA 1SGHA 3U7DA 1K5DB 3O96A 1ZSQA 5J3TA 3HQCA 2RUKB 4KHBB 2DHJA 4EMOA 1NI2A 2CODA 4GPTB 4HATB 3ULBA 1PMSA 3D8DA 1X1FA 4HAZB 3VIAA 1U5FA 5JP4A 3KY9A 1WI1A 5C5BA 2I5FA 4EKUA 1V5MA 2E2XA 3CIKA 2VRWB 3AU4A 4HDOA 5HE2A 2NZ8B 3ZVRA 2GJYA 1UPRA 4CHMA 3PVUA 2ROZB 2I5CA 1U2BA 2GCJA 5C79A 2Y7BA 1GG3A 1W1HA 3V5WA 1UPQA 3NSUA 2ADZA 5KQ4A 1NU2A 4XWXA 1LB1A 2R09A 2LG1A 2MDXA 1FGYA 1NTVA 2QKMA 2V76A 1FB8A 5LONB 2D11A 2DHIA 4A6KA 4A6HA 1ZC3B 5D3VA 2W2XC 4MK0A 5D3YA 2J0JA 2DFKA 2AEHA 2PZ1A 1J19A 2COFA 5LOPB 2DKQA 1H4RA 1I2HA 1M7EA 2UVMA 1IRSA 3SO6A 3X23A 2DYQA 2W2WA 2Z0PA 2K2UA 2LOZA 1DDMA 2D9YA 5HE3A 2YSZA 4K2PA 4C0AA 2VSZA 2P0HA 2M38A 5L81A 3SV1A 3WA0A 2K2JA 4BBKA 2MFQA 1MIXA 3PSCA 4A6FA 3RCPA 3PVLA 4HAVB 2EMSA 2CAYA 2KGXB 2GCLA 3QWMA 4F7GA 3KRXA 3UZTA 2HE7A 1ISNA 1Q67A 4D0NB 4Z2MB 2OQBA 1GC6A 2Y8FA 2LOXA 4HB4B 3BJIA 1U5DA 2UZSA 4A5KA 2YS3A 1P3RA 2DX5A 1P5TA 3ODXA 3FM8C 2BCJA 2ROVA 5C16A 3PVWA 1MK9B 1X05A 1NTYA 4HDQA 2J0MA 1J0WA 4WJ7A 4KHAA 2Y8GA 2KCJA 5DI9B 1BWNA 3D8FA 4K81A 1MKEA 4IAPA 1V5UA 1U5EA 2UZRA 1MIZB 2MWNB 4HB3B 3F0WA 3HK0A 2D2QA 5HE1A 4L6EA 4TYZA 1DBHA 2N0YA 2I1JA 2RLOA 3GYOA 1B55A 4YONA 1EGXA 3ZDTA 1XODA 1W1DA 3MDBC 1FGZA 1RRPB 2LYDA 2Z0OA 3FSSA 2P0DA 2DX1A 5CLQB 4ZRKA 1E5WA 4PNKA 3WYFB 1U27A 5CLLB 3TFMA 1V88A 1OQNA 4P7IA 1I7AA 2NMBA 2L1CA 1TXDA 5EFXA 2DHKA 2RSGA 5J3QA 2X18A 4F7HA 4DX90 5JHHA 4HAXB 4GMXB 2YT0A 4GXBA 2GS0A 5KCVA 2D4QA 2KUPA 2RGNB 5JLJB 1WJ1A 1V61A 1PFJA 1V5PA 3BINA 5D3WA 3SUZA 5HE0A 1MAIA 5JHGA 2D9XA 5C5BB 3AJ4A 2DYNA 3KZ1A 1XR0B 3A98B 2G35A 4HB2B 1FHWA 2OTXA 1WGQA 2L2IA 1X86A 2EMTA 3KSYA 1WJMA 2Z0QA 2YT1A 1TQZA 4EJNA 1TJ6A 2YS1A 4TKNA 2D9WA 1DDWA 2H7EA 5D27A 4F7UP 1OMWA 1DDVA 1KZGA 1DYNA 3F5RA 2LKOA 2LULA 2N23A 1ZVRA 2QKLA 3ODWA 2RVBB 1AQCA 2DA0A 1U5GA 1Y19B 2R0DA 2YS5A 1K5GB 5DH9B 2CY5A 2MKRA 3M1IB 2FJLA 4DX8A 3N7CA 1KZ7A 2ZPYA 4WVFB 3LJUX 4HAWB 1H10A 3QIJA 3GYPA 3OANA 4KVGB 2VKIA 4CHJA 1UNPA 1EAZA 2DN6A 3ML4A 1XX0A 2HTHB 2CY4A 2YVCA 4KAXB 3AU5A 5FI0A 2P0FA 1M7RA 4DBBA 3DXCA 2D9VA 4K17A 3U8ZA 5KQ1A 2J59M 5J3YA 1UNQA 3MPXA 1OY2A 4PQ0A 2DKPA 4MT7A 2ELBA 3KRWA 4ZRIA 5FI1A 4A6FB 1FHXA 2DLWA 2RNRB 2COCA 1N3HA 1XD4A 2ELAA 1RJ2A 1WG7A 4NY0A 3QBVB 5DHFB 4HAUB 1P6SA 2EC1A 4MY6A 3IVFA 1FOEA 1U29A 2P8VA 3P7ZA 3VOQA 3DXDA 4H8SA 1FHOA 3TCAA 4NSWA 3P6AA 1X1GA 2W2XD 2I1KA 4HB0B 4IFSA 3TVVA 2IFSA 2AL6A 1PLSA 1MPHA 3FEHA
chains in the Genus database with same CATH superfamily
1ZM0A 1WGUA 2JP2A 1BTKA 1BAKA 1AWEA 5C6RA 2Q13A 4ZRJA 4B6HA 3D8EA 1SHCA 2D9ZA 1WVHA 3A8PA 5D3XA 1V89A 5GOWB 4GMVA 3G9WA 1UNRA 4HAYB 1Z87A 1ZYIA 4WSFA 4Y94A 1UEFA 1QC6A 4GOUA 3SYXA 2XQNM 1XCGA 2CRFA 4HHVA 3T06A 1KI1B 2COAA 2D10A 2IYBA 3PG7A 1FAOA 1XKEA 3TW1A 4QJ4B 3HIEA 3ULCA 2J0KA 4CYEA 3U12A 4GZUA 4K2OA 3HSAA 2YF0A 3PEGA 4GN1A 2ZKMX 1LW3A 1QQGA 5DIFB 5I2MA 1W1GA 3HW2B 2KR0A 1Y5OA 4DXAB 1EF1A 2DTCA 3SNHA 1MK7B 3CXBB 1X11A 4Z2NA 5DHAB 4KHOA 2K8EA 4YL8A 3TO1A 3PP2A 1EVHA 2KIGA 3DXEA 3PZDA 2M14A 1ZC4B 2H7DA 1DROA 2YRYA 2K00A 3A8QA 2EJ8A 1GC7A 4IOYX 1BTNA 3ODOA 1SGHA 3U7DA 1K5DB 3O96A 1ZSQA 5J3TA 3HQCA 2RUKB 4KHBB 2DHJA 4EMOA 1NI2A 2CODA 1T77A 4GPTB 4HATB 3ULBA 3A58A 1PMSA 3D8DA 1X1FA 4HAZB 3VIAA 1U5FA 5JP4A 3KY9A 1WI1A 5C5BA 2I5FA 4EKUA 1MI1A 1V5MA 2E2XA 3CIKA 2VRWB 3AU4A 4HDOA 4DIXA 5HE2A 2NZ8B 3ZVRA 2GJYA 1UPRA 4CHMA 3PVUA 2ROZB 2I5CA 2K49A 2Z14A 1U2BA 2GCJA 5C79A 2Y7BA 1GG3A 1W1HA 2RRFA 3V5WA 1UPQA 3NSUA 2ADZA 5KQ4A 1NU2A 4XWXA 1LB1A 2R09A 2LG1A 2MDXA 1FGYA 1NTVA 2V76A 2QKMA 1FB8A 5LONB 2D11A 2DHIA 4A6KA 4A6HA 1ZC3B 5D3VA 2W2XC 4MK0A 5D3YA 2J0JA 2DFKA 2AEHA 2PZ1A 1J19A 2COFA 5LOPB 2DKQA 1H4RA 1I2HA 1M7EA 2UVMA 1IRSA 3SO6A 3X23A 2DYQA 3OHMB 2W2WA 2Z0PA 2K2UA 2LOZA 1DDMA 5LG4B 2FJUB 2D9YA 5I2SA 5HE3A 2YSZA 4K2PA 4C0AA 2VSZA 2R2YA 2P0HA 2M38A 5L81A 3SV1A 3WA0A 2K2JA 2NBVA 4BBKA 2MFQA 3B77A 1MIXA 3PSCA 4A6FA 3RCPA 3PVLA 4HAVB 2EMSA 2CAYA 2KGXB 2GCLA 3QWMA 4F7GA 3KRXA 3UZTA 2HE7A 1ISNA 1Q67A 4D0NB 4Z2MB 2OQBA 3FVCA 1GC6A 2Y8FA 2LOXA 4HB4B 3BJIA 1U5DA 2UZSA 4A5KA 2YS3A 1P3RA 2DX5A 1P5TA 3ODXA 3FM8C 2BCJA 2KIEA 2ROVA 5C16A 3PVWA 1MK9B 1X05A 1NTYA 4HDQA 2J0MA 1J0WA 4WJ7A 4KHAA 2Y8GA 2KCJA 5DI9B 1BWNA 3D8FA 4K81A 1MKEA 4IAPA 1V5UA 1U5EA 2UZRA 1MIZB 2MWNB 4HB3B 3F0WA 3HK0A 2D2QA 5HE1A 4L6EA 4TYZA 1DBHA 2N0YA 2I1JA 2RLOA 3NW8A 3GYOA 1B55A 3NWAA 4YONA 1EGXA 2GUMA 3ZDTA 1XODA 1W1DA 3MDBC 1FGZA 1RRPB 2LYDA 2Z0OA 3FSSA 2P0DA 2DX1A 5CLQB 4ZRKA 1E5WA 5IRSA 4PNKA 2KUQA 1U27A 3WYFB 5CLLB 3TFMA 1V88A 1OQNA 4P7IA 1I7AA 2NMBA 2L1CA 1TXDA 5EFXA 2DHKA 2RSGA 5J3QA 2X18A 4F7HA 4DX90 5JHHA 4HAXB 4GMXB 2YT0A 4GXBA 2GS0A 5KCVA 2D4QA 2KUPA 2RGNB 5JLJB 1WJ1A 1V61A 1PFJA 1V5PA 3BINA 5D3WA 3SUZA 5HE0A 1MAIA 5JHGA 2D9XA 5C5BB 3AJ4A 2DYNA 1XR0B 3KZ1A 3A98B 2G35A 3NWDA 1FHWA 4HB2B 2OTXA 1WGQA 4L1RA 2L2IA 1X86A 2EMTA 3KSYA 1WJMA 2Z0QA 2YT1A 1TQZA 4D6WA 4EJNA 5M4YB 1TJ6A 2YS1A 4TKNA 2D9WA 1DDWA 2H7EA 5D27A 4F7UP 1OMWA 1DDVA 1KZGA 4QJ3B 1DYNA 3F5RA 2LKOA 2LULA 2N23A 1ZVRA 2QKLA 3ODWA 2RVBB 1AQCA 2DA0A 1U5GA 1Y19B 2R0DA 4KHBA 2YS5A 1K5GB 5DH9B 2CY5A 2MKRA 3M1IB 2FJLA 4DX8A 2Z13A 3N7CA 1KZ7A 2ZPYA 4CSQA 4WVFB 3LJUX 4HAWB 1H10A 3QIJA 3GYPA 3OANA 4KVGB 3NWFA 2VKIA 4CHJA 1UNPA 1EAZA 4HSIA 2DN6A 3ML4A 1XX0A 2HTHB 2CY4A 2YVCA 4KAXB 3AU5A 5FI0A 4QXAB 2P0FA 4GNKB 3DCXA 1M7RA 4DBBA 3DXCA 2D9VA 4K17A 3U8ZA 5KQ1A 2J59M 5J3YA 2Z4DA 1UNQA 3MPXA 1OY2A 4PQ0A 2DKPA 4MT7A 2ELBA 3KRWA 4ZRIA 5FI1A 4OSNA 4A6FB 1FHXA 2DLWA 2RNRB 2COCA 1N3HA 1XD4A 2ELAA 1RJ2A 1WG7A 4QJ5B 4NY0A 2Z59A 3QBVB 5DHFB 2YT2A 4HAUB 4OT1A 1P6SA 2EC1A 4MY6A 3IVFA 1FOEA 1U29A 2P8VA 3P7ZA 3VOQA 3DXDA 4H8SA 1FHOA 3TCAA 4NSWA 3P6AA 1X1GA 2W2XD 2I1KA 4HB0B 4IFSA 3TVVA 2IFSA 2AL6A 1PLSA 1MPHA 3FEHA
chains in the Genus database with same CATH topology
1ZM0A 1WGUA 2JP2A 1BTKA 1BAKA 1AWEA 5C6RA 2Q13A 4ZRJA 4B6HA 3D8EA 1SHCA 2D9ZA 1WVHA 3A8PA 5D3XA 1V89A 5GOWB 4GMVA 3G9WA 1UNRA 4HAYB 1Z87A 4WSFA 4Y94A 1UEFA 1QC6A 3SYXA 2XQNM 1XCGA 2CRFA 4HHVA 3T06A 1KI1B 2COAA 2D10A 2IYBA 3PG7A 1FAOA 1XKEA 3TW1A 3ULCA 2J0KA 4CYEA 4GZUA 4K2OA 2YF0A 3PEGA 4GN1A 1LW3A 1QQGA 5DIFB 1W1GA 3HW2B 1Y5OA 4DXAB 1EF1A 2DTCA 3SNHA 1MK7B 3CXBB 1X11A 4Z2NA 5DHAB 4KHOA 4YL8A 3TO1A 3PP2A 1EVHA 3DXEA 3PZDA 2M14A 1ZC4B 2H7DA 1DROA 2YRYA 2K00A 3A8QA 2EJ8A 1GC7A 4IOYX 1BTNA 3ODOA 1SGHA 3U7DA 1K5DB 3O96A 1ZSQA 5J3TA 3HQCA 2RUKB 4KHBB 2DHJA 4EMOA 1NI2A 2CODA 4GPTB 4HATB 3ULBA 1PMSA 3D8DA 1X1FA 4HAZB 3VIAA 1U5FA 5JP4A 3KY9A 1WI1A 5C5BA 2I5FA 4EKUA 1V5MA 2E2XA 3CIKA 2VRWB 3AU4A 4HDOA 5HE2A 2NZ8B 3ZVRA 2GJYA 1UPRA 4CHMA 3PVUA 2ROZB 2I5CA 1U2BA 2GCJA 5C79A 2Y7BA 1GG3A 1W1HA 3V5WA 1UPQA 3NSUA 2ADZA 5KQ4A 1NU2A 4XWXA 1LB1A 2R09A 2LG1A 2MDXA 1FGYA 1NTVA 2QKMA 2V76A 1FB8A 5LONB 2D11A 2DHIA 4A6KA 4A6HA 1ZC3B 5D3VA 2W2XC 4MK0A 5D3YA 2J0JA 2DFKA 2AEHA 2PZ1A 1J19A 2COFA 5LOPB 2DKQA 1H4RA 1I2HA 1M7EA 2UVMA 1IRSA 3SO6A 3X23A 2DYQA 2W2WA 2Z0PA 2K2UA 2LOZA 1DDMA 2D9YA 5HE3A 2YSZA 4K2PA 4C0AA 2VSZA 2P0HA 2M38A 5L81A 3SV1A 3WA0A 2K2JA 4BBKA 2MFQA 1MIXA 3PSCA 4A6FA 3RCPA 3PVLA 4HAVB 2EMSA 2CAYA 2KGXB 2GCLA 3QWMA 4F7GA 3KRXA 3UZTA 2HE7A 1ISNA 1Q67A 4D0NB 4Z2MB 2OQBA 1GC6A 2Y8FA 2LOXA 4HB4B 3BJIA 1U5DA 2UZSA 4A5KA 2YS3A 1P3RA 2DX5A 1P5TA 3ODXA 3FM8C 2BCJA 2ROVA 5C16A 3PVWA 1MK9B 1X05A 1NTYA 4HDQA 2J0MA 1J0WA 4WJ7A 4KHAA 2Y8GA 2KCJA 5DI9B 1BWNA 3D8FA 4K81A 1MKEA 4IAPA 1V5UA 1U5EA 2UZRA 1MIZB 2MWNB 4HB3B 3F0WA 3HK0A 2D2QA 5HE1A 4L6EA 4TYZA 1DBHA 2N0YA 2I1JA 2RLOA 3GYOA 1B55A 4YONA 1EGXA 3ZDTA 1XODA 1W1DA 3MDBC 1FGZA 1RRPB 2LYDA 2Z0OA 3FSSA 2P0DA 2DX1A 5CLQB 4ZRKA 1E5WA 4PNKA 3WYFB 1U27A 5CLLB 3TFMA 1V88A 1OQNA 4P7IA 1I7AA 2NMBA 2L1CA 1TXDA 5EFXA 2DHKA 2RSGA 5J3QA 2X18A 4F7HA 4DX90 5JHHA 4HAXB 4GMXB 2YT0A 4GXBA 2GS0A 5KCVA 2D4QA 2KUPA 2RGNB 5JLJB 1WJ1A 1V61A 1PFJA 1V5PA 3BINA 5D3WA 3SUZA 5HE0A 1MAIA 5JHGA 2D9XA 5C5BB 3AJ4A 2DYNA 3KZ1A 1XR0B 3A98B 2G35A 4HB2B 1FHWA 2OTXA 1WGQA 2L2IA 1X86A 2EMTA 3KSYA 1WJMA 2Z0QA 2YT1A 1TQZA 4EJNA 1TJ6A 2YS1A 4TKNA 2D9WA 1DDWA 2H7EA 5D27A 4F7UP 1OMWA 1DDVA 1KZGA 1DYNA 3F5RA 2LKOA 2LULA 2N23A 1ZVRA 2QKLA 3ODWA 2RVBB 1AQCA 2DA0A 1U5GA 1Y19B 2R0DA 2YS5A 1K5GB 5DH9B 2CY5A 2MKRA 3M1IB 2FJLA 4DX8A 3N7CA 1KZ7A 2ZPYA 4WVFB 3LJUX 4HAWB 1H10A 3QIJA 3GYPA 3OANA 4KVGB 2VKIA 4CHJA 1UNPA 1EAZA 2DN6A 3ML4A 1XX0A 2HTHB 2CY4A 2YVCA 4KAXB 3AU5A 5FI0A 2P0FA 1M7RA 4DBBA 3DXCA 2D9VA 4K17A 3U8ZA 5KQ1A 2J59M 5J3YA 1UNQA 3MPXA 1OY2A 4PQ0A 2DKPA 4MT7A 2ELBA 3KRWA 4ZRIA 5FI1A 4A6FB 1FHXA 2DLWA 2RNRB 2COCA 1N3HA 1XD4A 2ELAA 1RJ2A 1WG7A 4NY0A 3QBVB 5DHFB 4HAUB 1P6SA 2EC1A 4MY6A 3IVFA 1FOEA 1U29A 2P8VA 3P7ZA 3VOQA 3DXDA 4H8SA 1FHOA 3TCAA 4NSWA 3P6AA 1X1GA 2W2XD 2I1KA 4HB0B 4IFSA 3TVVA 2IFSA 2AL6A 1PLSA 1MPHA 3FEHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZM0 A;  1WGU A;  2JP2 A;  1BTK A;  1BAK A;  1AWE A;  5C6R A;  2Q13 A;  4ZRJ A;  4B6H A;  3D8E A;  1SHC A;  2D9Z A;  1WVH A;  3A8P A;  5D3X A;  1V89 A;  5GOW B;  4GMV A;  3G9W A;  1UNR A;  4HAY B;  1Z87 A;  4WSF A;  4Y94 A;  1UEF A;  1QC6 A;  3SYX A;  2XQN M;  1XCG A;  2CRF A;  4HHV A;  3T06 A;  1KI1 B;  2COA A;  2D10 A;  2IYB A;  3PG7 A;  1FAO A;  1XKE A;  3TW1 A;  3ULC A;  2J0K A;  4CYE A;  4GZU A;  4K2O A;  2YF0 A;  3PEG A;  4GN1 A;  1LW3 A;  1QQG A;  5DIF B;  1W1G A;  3HW2 B;  1Y5O A;  4DXA B;  1EF1 A;  2DTC A;  3SNH A;  1MK7 B;  3CXB B;  1X11 A;  4Z2N A;  5DHA B;  4KHO A;  4YL8 A;  3TO1 A;  3PP2 A;  1EVH A;  3DXE A;  3PZD A;  2M14 A;  1ZC4 B;  2H7D A;  1DRO A;  2YRY A;  2K00 A;  3A8Q A;  2EJ8 A;  1GC7 A;  4IOY X;  1BTN A;  3ODO A;  1SGH A;  3U7D A;  1K5D B;  3O96 A;  1ZSQ A;  5J3T A;  3HQC A;  2RUK B;  4KHB B;  2DHJ A;  4EMO A;  1NI2 A;  2COD A;  4GPT B;  4HAT B;  3ULB A;  1PMS A;  3D8D A;  1X1F A;  4HAZ B;  3VIA A;  1U5F A;  5JP4 A;  3KY9 A;  1WI1 A;  5C5B A;  2I5F A;  4EKU A;  1V5M A;  2E2X A;  3CIK A;  2VRW B;  3AU4 A;  4HDO A;  5HE2 A;  2NZ8 B;  3ZVR A;  2GJY A;  1UPR A;  4CHM A;  3PVU A;  2ROZ B;  2I5C A;  1U2B A;  2GCJ A;  5C79 A;  2Y7B A;  1GG3 A;  1W1H A;  3V5W A;  1UPQ A;  3NSU A;  2ADZ A;  5KQ4 A;  1NU2 A;  4XWX A;  1LB1 A;  2R09 A;  2LG1 A;  2MDX A;  1FGY A;  1NTV A;  2QKM A;  2V76 A;  1FB8 A;  5LON B;  2D11 A;  2DHI A;  4A6K A;  4A6H A;  1ZC3 B;  5D3V A;  2W2X C;  4MK0 A;  5D3Y A;  2J0J A;  2DFK A;  2AEH A;  2PZ1 A;  1J19 A;  2COF A;  5LOP B;  2DKQ A;  1H4R A;  1I2H A;  1M7E A;  2UVM A;  1IRS A;  3SO6 A;  3X23 A;  2DYQ A;  2W2W A;  2Z0P A;  2K2U A;  2LOZ A;  1DDM A;  2D9Y A;  5HE3 A;  2YSZ A;  4K2P A;  4C0A A;  2VSZ A;  2P0H A;  2M38 A;  5L81 A;  3SV1 A;  3WA0 A;  2K2J A;  4BBK A;  2MFQ A;  1MIX A;  3PSC A;  4A6F A;  3RCP A;  3PVL A;  4HAV B;  2EMS A;  2CAY A;  2KGX B;  2GCL A;  3QWM A;  4F7G A;  3KRX A;  3UZT A;  2HE7 A;  1ISN A;  1Q67 A;  4D0N B;  4Z2M B;  2OQB A;  1GC6 A;  2Y8F A;  2LOX A;  4HB4 B;  3BJI A;  1U5D A;  2UZS A;  4A5K A;  2YS3 A;  1P3R A;  2DX5 A;  1P5T A;  3ODX A;  3FM8 C;  2BCJ A;  2ROV A;  5C16 A;  3PVW A;  1MK9 B;  1X05 A;  1NTY A;  4HDQ A;  2J0M A;  1J0W A;  4WJ7 A;  4KHA A;  2Y8G A;  2KCJ A;  5DI9 B;  1BWN A;  3D8F A;  4K81 A;  1MKE A;  4IAP A;  1V5U A;  1U5E A;  2UZR A;  1MIZ B;  2MWN B;  4HB3 B;  3F0W A;  3HK0 A;  2D2Q A;  5HE1 A;  4L6E A;  4TYZ A;  1DBH A;  2N0Y A;  2I1J A;  2RLO A;  3GYO A;  1B55 A;  4YON A;  1EGX A;  3ZDT A;  1XOD A;  1W1D A;  3MDB C;  1FGZ A;  1RRP B;  2LYD A;  2Z0O A;  3FSS A;  2P0D A;  2DX1 A;  5CLQ B;  4ZRK A;  1E5W A;  4PNK A;  3WYF B;  1U27 A;  5CLL B;  3TFM A;  1V88 A;  1OQN A;  4P7I A;  1I7A A;  2NMB A;  2L1C A;  1TXD A;  5EFX A;  2DHK A;  2RSG A;  5J3Q A;  2X18 A;  4F7H A;  4DX9 0;  5JHH A;  4HAX B;  4GMX B;  2YT0 A;  4GXB A;  2GS0 A;  5KCV A;  2D4Q A;  2KUP A;  2RGN B;  5JLJ B;  1WJ1 A;  1V61 A;  1PFJ A;  1V5P A;  3BIN A;  5D3W A;  3SUZ A;  5HE0 A;  1MAI A;  5JHG A;  2D9X A;  5C5B B;  3AJ4 A;  2DYN A;  3KZ1 A;  1XR0 B;  3A98 B;  2G35 A;  4HB2 B;  1FHW A;  2OTX A;  1WGQ A;  2L2I A;  1X86 A;  2EMT A;  3KSY A;  1WJM A;  2Z0Q A;  2YT1 A;  1TQZ A;  4EJN A;  1TJ6 A;  2YS1 A;  4TKN A;  2D9W A;  1DDW A;  2H7E A;  5D27 A;  4F7U P;  1OMW A;  1DDV A;  1KZG A;  1DYN A;  3F5R A;  2LKO A;  2LUL A;  2N23 A;  1ZVR A;  2QKL A;  3ODW A;  2RVB B;  1AQC A;  2DA0 A;  1U5G A;  1Y19 B;  2R0D A;  2YS5 A;  1K5G B;  5DH9 B;  2CY5 A;  2MKR A;  3M1I B;  2FJL A;  4DX8 A;  3N7C A;  1KZ7 A;  2ZPY A;  4WVF B;  3LJU X;  4HAW B;  1H10 A;  3QIJ A;  3GYP A;  3OAN A;  4KVG B;  2VKI A;  4CHJ A;  1UNP A;  1EAZ A;  2DN6 A;  3ML4 A;  1XX0 A;  2HTH B;  2CY4 A;  2YVC A;  4KAX B;  3AU5 A;  5FI0 A;  2P0F A;  1M7R A;  4DBB A;  3DXC A;  2D9V A;  4K17 A;  3U8Z A;  5KQ1 A;  2J59 M;  5J3Y A;  1UNQ A;  3MPX A;  1OY2 A;  4PQ0 A;  2DKP A;  4MT7 A;  2ELB A;  3KRW A;  4ZRI A;  5FI1 A;  4A6F B;  1FHX A;  2DLW A;  2RNR B;  2COC A;  1N3H A;  1XD4 A;  2ELA A;  1RJ2 A;  1WG7 A;  4NY0 A;  3QBV B;  5DHF B;  4HAU B;  1P6S A;  2EC1 A;  4MY6 A;  3IVF A;  1FOE A;  1U29 A;  2P8V A;  3P7Z A;  3VOQ A;  3DXD A;  4H8S A;  1FHO A;  3TCA A;  4NSW A;  3P6A A;  1X1G A;  2W2X D;  2I1K A;  4HB0 B;  4IFS A;  3TVV A;  2IFS A;  2AL6 A;  1PLS A;  1MPH A;  3FEH A; 
#chains in the Genus database with same CATH topology
 1ZM0 A;  1WGU A;  2JP2 A;  1BTK A;  1BAK A;  1AWE A;  5C6R A;  2Q13 A;  4ZRJ A;  4B6H A;  3D8E A;  1SHC A;  2D9Z A;  1WVH A;  3A8P A;  5D3X A;  1V89 A;  5GOW B;  4GMV A;  3G9W A;  1UNR A;  4HAY B;  1Z87 A;  1ZYI A;  4WSF A;  4Y94 A;  1UEF A;  1QC6 A;  4GOU A;  3SYX A;  2XQN M;  1XCG A;  2CRF A;  4HHV A;  3T06 A;  1KI1 B;  2COA A;  2D10 A;  2IYB A;  3PG7 A;  1FAO A;  1XKE A;  3TW1 A;  4QJ4 B;  3HIE A;  3ULC A;  2J0K A;  4CYE A;  3U12 A;  4GZU A;  4K2O A;  3HSA A;  2YF0 A;  3PEG A;  4GN1 A;  2ZKM X;  1LW3 A;  1QQG A;  5DIF B;  5I2M A;  1W1G A;  3HW2 B;  2KR0 A;  1Y5O A;  4DXA B;  1EF1 A;  2DTC A;  3SNH A;  1MK7 B;  3CXB B;  1X11 A;  4Z2N A;  5DHA B;  4KHO A;  2K8E A;  4YL8 A;  3TO1 A;  3PP2 A;  1EVH A;  2KIG A;  3DXE A;  3PZD A;  2M14 A;  1ZC4 B;  2H7D A;  1DRO A;  2YRY A;  2K00 A;  3A8Q A;  2EJ8 A;  1GC7 A;  4IOY X;  1BTN A;  3ODO A;  1SGH A;  3U7D A;  1K5D B;  3O96 A;  1ZSQ A;  5J3T A;  3HQC A;  2RUK B;  4KHB B;  2DHJ A;  4EMO A;  1NI2 A;  2COD A;  1T77 A;  4GPT B;  4HAT B;  3ULB A;  3A58 A;  1PMS A;  3D8D A;  1X1F A;  4HAZ B;  3VIA A;  1U5F A;  5JP4 A;  3KY9 A;  1WI1 A;  5C5B A;  2I5F A;  4EKU A;  1MI1 A;  1V5M A;  2E2X A;  3CIK A;  2VRW B;  3AU4 A;  4HDO A;  4DIX A;  5HE2 A;  2NZ8 B;  3ZVR A;  2GJY A;  1UPR A;  4CHM A;  3PVU A;  2ROZ B;  2I5C A;  2K49 A;  2Z14 A;  1U2B A;  2GCJ A;  5C79 A;  2Y7B A;  1GG3 A;  1W1H A;  2RRF A;  3V5W A;  1UPQ A;  3NSU A;  2ADZ A;  5KQ4 A;  1NU2 A;  4XWX A;  1LB1 A;  2R09 A;  2LG1 A;  2MDX A;  1FGY A;  1NTV A;  2V76 A;  2QKM A;  1FB8 A;  5LON B;  2D11 A;  2DHI A;  4A6K A;  4A6H A;  1ZC3 B;  5D3V A;  2W2X C;  4MK0 A;  5D3Y A;  2J0J A;  2DFK A;  2AEH A;  2PZ1 A;  1J19 A;  2COF A;  5LOP B;  2DKQ A;  1H4R A;  1I2H A;  1M7E A;  2UVM A;  1IRS A;  3SO6 A;  3X23 A;  2DYQ A;  3OHM B;  2W2W A;  2Z0P A;  2K2U A;  2LOZ A;  1DDM A;  5LG4 B;  2FJU B;  2D9Y A;  5I2S A;  5HE3 A;  2YSZ A;  4K2P A;  4C0A A;  2VSZ A;  2R2Y A;  2P0H A;  2M38 A;  5L81 A;  3SV1 A;  3WA0 A;  2K2J A;  2NBV A;  4BBK A;  2MFQ A;  3B77 A;  1MIX A;  3PSC A;  4A6F A;  3RCP A;  3PVL A;  4HAV B;  2EMS A;  2CAY A;  2KGX B;  2GCL A;  3QWM A;  4F7G A;  3KRX A;  3UZT A;  2HE7 A;  1ISN A;  1Q67 A;  4D0N B;  4Z2M B;  2OQB A;  3FVC A;  1GC6 A;  2Y8F A;  2LOX A;  4HB4 B;  3BJI A;  1U5D A;  2UZS A;  4A5K A;  2YS3 A;  1P3R A;  2DX5 A;  1P5T A;  3ODX A;  3FM8 C;  2BCJ A;  2KIE A;  2ROV A;  5C16 A;  3PVW A;  1MK9 B;  1X05 A;  1NTY A;  4HDQ A;  2J0M A;  1J0W A;  4WJ7 A;  4KHA A;  2Y8G A;  2KCJ A;  5DI9 B;  1BWN A;  3D8F A;  4K81 A;  1MKE A;  4IAP A;  1V5U A;  1U5E A;  2UZR A;  1MIZ B;  2MWN B;  4HB3 B;  3F0W A;  3HK0 A;  2D2Q A;  5HE1 A;  4L6E A;  4TYZ A;  1DBH A;  2N0Y A;  2I1J A;  2RLO A;  3NW8 A;  3GYO A;  1B55 A;  3NWA A;  4YON A;  1EGX A;  2GUM A;  3ZDT A;  1XOD A;  1W1D A;  3MDB C;  1FGZ A;  1RRP B;  2LYD A;  2Z0O A;  3FSS A;  2P0D A;  2DX1 A;  5CLQ B;  4ZRK A;  1E5W A;  5IRS A;  4PNK A;  2KUQ A;  1U27 A;  3WYF B;  5CLL B;  3TFM A;  1V88 A;  1OQN A;  4P7I A;  1I7A A;  2NMB A;  2L1C A;  1TXD A;  5EFX A;  2DHK A;  2RSG A;  5J3Q A;  2X18 A;  4F7H A;  4DX9 0;  5JHH A;  4HAX B;  4GMX B;  2YT0 A;  4GXB A;  2GS0 A;  5KCV A;  2D4Q A;  2KUP A;  2RGN B;  5JLJ B;  1WJ1 A;  1V61 A;  1PFJ A;  1V5P A;  3BIN A;  5D3W A;  3SUZ A;  5HE0 A;  1MAI A;  5JHG A;  2D9X A;  5C5B B;  3AJ4 A;  2DYN A;  1XR0 B;  3KZ1 A;  3A98 B;  2G35 A;  3NWD A;  1FHW A;  4HB2 B;  2OTX A;  1WGQ A;  4L1R A;  2L2I A;  1X86 A;  2EMT A;  3KSY A;  1WJM A;  2Z0Q A;  2YT1 A;  1TQZ A;  4D6W A;  4EJN A;  5M4Y B;  1TJ6 A;  2YS1 A;  4TKN A;  2D9W A;  1DDW A;  2H7E A;  5D27 A;  4F7U P;  1OMW A;  1DDV A;  1KZG A;  4QJ3 B;  1DYN A;  3F5R A;  2LKO A;  2LUL A;  2N23 A;  1ZVR A;  2QKL A;  3ODW A;  2RVB B;  1AQC A;  2DA0 A;  1U5G A;  1Y19 B;  2R0D A;  4KHB A;  2YS5 A;  1K5G B;  5DH9 B;  2CY5 A;  2MKR A;  3M1I B;  2FJL A;  4DX8 A;  2Z13 A;  3N7C A;  1KZ7 A;  2ZPY A;  4CSQ A;  4WVF B;  3LJU X;  4HAW B;  1H10 A;  3QIJ A;  3GYP A;  3OAN A;  4KVG B;  3NWF A;  2VKI A;  4CHJ A;  1UNP A;  1EAZ A;  4HSI A;  2DN6 A;  3ML4 A;  1XX0 A;  2HTH B;  2CY4 A;  2YVC A;  4KAX B;  3AU5 A;  5FI0 A;  4QXA B;  2P0F A;  4GNK B;  3DCX A;  1M7R A;  4DBB A;  3DXC A;  2D9V A;  4K17 A;  3U8Z A;  5KQ1 A;  2J59 M;  5J3Y A;  2Z4D A;  1UNQ A;  3MPX A;  1OY2 A;  4PQ0 A;  2DKP A;  4MT7 A;  2ELB A;  3KRW A;  4ZRI A;  5FI1 A;  4OSN A;  4A6F B;  1FHX A;  2DLW A;  2RNR B;  2COC A;  1N3H A;  1XD4 A;  2ELA A;  1RJ2 A;  1WG7 A;  4QJ5 B;  4NY0 A;  2Z59 A;  3QBV B;  5DHF B;  2YT2 A;  4HAU B;  4OT1 A;  1P6S A;  2EC1 A;  4MY6 A;  3IVF A;  1FOE A;  1U29 A;  2P8V A;  3P7Z A;  3VOQ A;  3DXD A;  4H8S A;  1FHO A;  3TCA A;  4NSW A;  3P6A A;  1X1G A;  2W2X D;  2I1K A;  4HB0 B;  4IFS A;  3TVV A;  2IFS A;  2AL6 A;  1PLS A;  1MPH A;  3FEH A; 
#chains in the Genus database with same CATH homology
 1ZM0 A;  1WGU A;  2JP2 A;  1BTK A;  1BAK A;  1AWE A;  5C6R A;  2Q13 A;  4ZRJ A;  4B6H A;  3D8E A;  1SHC A;  2D9Z A;  1WVH A;  3A8P A;  5D3X A;  1V89 A;  5GOW B;  4GMV A;  3G9W A;  1UNR A;  4HAY B;  1Z87 A;  4WSF A;  4Y94 A;  1UEF A;  1QC6 A;  3SYX A;  2XQN M;  1XCG A;  2CRF A;  4HHV A;  3T06 A;  1KI1 B;  2COA A;  2D10 A;  2IYB A;  3PG7 A;  1FAO A;  1XKE A;  3TW1 A;  3ULC A;  2J0K A;  4CYE A;  4GZU A;  4K2O A;  2YF0 A;  3PEG A;  4GN1 A;  1LW3 A;  1QQG A;  5DIF B;  1W1G A;  3HW2 B;  1Y5O A;  4DXA B;  1EF1 A;  2DTC A;  3SNH A;  1MK7 B;  3CXB B;  1X11 A;  4Z2N A;  5DHA B;  4KHO A;  4YL8 A;  3TO1 A;  3PP2 A;  1EVH A;  3DXE A;  3PZD A;  2M14 A;  1ZC4 B;  2H7D A;  1DRO A;  2YRY A;  2K00 A;  3A8Q A;  2EJ8 A;  1GC7 A;  4IOY X;  1BTN A;  3ODO A;  1SGH A;  3U7D A;  1K5D B;  3O96 A;  1ZSQ A;  5J3T A;  3HQC A;  2RUK B;  4KHB B;  2DHJ A;  4EMO A;  1NI2 A;  2COD A;  4GPT B;  4HAT B;  3ULB A;  1PMS A;  3D8D A;  1X1F A;  4HAZ B;  3VIA A;  1U5F A;  5JP4 A;  3KY9 A;  1WI1 A;  5C5B A;  2I5F A;  4EKU A;  1V5M A;  2E2X A;  3CIK A;  2VRW B;  3AU4 A;  4HDO A;  5HE2 A;  2NZ8 B;  3ZVR A;  2GJY A;  1UPR A;  4CHM A;  3PVU A;  2ROZ B;  2I5C A;  1U2B A;  2GCJ A;  5C79 A;  2Y7B A;  1GG3 A;  1W1H A;  3V5W A;  1UPQ A;  3NSU A;  2ADZ A;  5KQ4 A;  1NU2 A;  4XWX A;  1LB1 A;  2R09 A;  2LG1 A;  2MDX A;  1FGY A;  1NTV A;  2QKM A;  2V76 A;  1FB8 A;  5LON B;  2D11 A;  2DHI A;  4A6K A;  4A6H A;  1ZC3 B;  5D3V A;  2W2X C;  4MK0 A;  5D3Y A;  2J0J A;  2DFK A;  2AEH A;  2PZ1 A;  1J19 A;  2COF A;  5LOP B;  2DKQ A;  1H4R A;  1I2H A;  1M7E A;  2UVM A;  1IRS A;  3SO6 A;  3X23 A;  2DYQ A;  2W2W A;  2Z0P A;  2K2U A;  2LOZ A;  1DDM A;  2D9Y A;  5HE3 A;  2YSZ A;  4K2P A;  4C0A A;  2VSZ A;  2P0H A;  2M38 A;  5L81 A;  3SV1 A;  3WA0 A;  2K2J A;  4BBK A;  2MFQ A;  1MIX A;  3PSC A;  4A6F A;  3RCP A;  3PVL A;  4HAV B;  2EMS A;  2CAY A;  2KGX B;  2GCL A;  3QWM A;  4F7G A;  3KRX A;  3UZT A;  2HE7 A;  1ISN A;  1Q67 A;  4D0N B;  4Z2M B;  2OQB A;  1GC6 A;  2Y8F A;  2LOX A;  4HB4 B;  3BJI A;  1U5D A;  2UZS A;  4A5K A;  2YS3 A;  1P3R A;  2DX5 A;  1P5T A;  3ODX A;  3FM8 C;  2BCJ A;  2ROV A;  5C16 A;  3PVW A;  1MK9 B;  1X05 A;  1NTY A;  4HDQ A;  2J0M A;  1J0W A;  4WJ7 A;  4KHA A;  2Y8G A;  2KCJ A;  5DI9 B;  1BWN A;  3D8F A;  4K81 A;  1MKE A;  4IAP A;  1V5U A;  1U5E A;  2UZR A;  1MIZ B;  2MWN B;  4HB3 B;  3F0W A;  3HK0 A;  2D2Q A;  5HE1 A;  4L6E A;  4TYZ A;  1DBH A;  2N0Y A;  2I1J A;  2RLO A;  3GYO A;  1B55 A;  4YON A;  1EGX A;  3ZDT A;  1XOD A;  1W1D A;  3MDB C;  1FGZ A;  1RRP B;  2LYD A;  2Z0O A;  3FSS A;  2P0D A;  2DX1 A;  5CLQ B;  4ZRK A;  1E5W A;  4PNK A;  3WYF B;  1U27 A;  5CLL B;  3TFM A;  1V88 A;  1OQN A;  4P7I A;  1I7A A;  2NMB A;  2L1C A;  1TXD A;  5EFX A;  2DHK A;  2RSG A;  5J3Q A;  2X18 A;  4F7H A;  4DX9 0;  5JHH A;  4HAX B;  4GMX B;  2YT0 A;  4GXB A;  2GS0 A;  5KCV A;  2D4Q A;  2KUP A;  2RGN B;  5JLJ B;  1WJ1 A;  1V61 A;  1PFJ A;  1V5P A;  3BIN A;  5D3W A;  3SUZ A;  5HE0 A;  1MAI A;  5JHG A;  2D9X A;  5C5B B;  3AJ4 A;  2DYN A;  3KZ1 A;  1XR0 B;  3A98 B;  2G35 A;  4HB2 B;  1FHW A;  2OTX A;  1WGQ A;  2L2I A;  1X86 A;  2EMT A;  3KSY A;  1WJM A;  2Z0Q A;  2YT1 A;  1TQZ A;  4EJN A;  1TJ6 A;  2YS1 A;  4TKN A;  2D9W A;  1DDW A;  2H7E A;  5D27 A;  4F7U P;  1OMW A;  1DDV A;  1KZG A;  1DYN A;  3F5R A;  2LKO A;  2LUL A;  2N23 A;  1ZVR A;  2QKL A;  3ODW A;  2RVB B;  1AQC A;  2DA0 A;  1U5G A;  1Y19 B;  2R0D A;  2YS5 A;  1K5G B;  5DH9 B;  2CY5 A;  2MKR A;  3M1I B;  2FJL A;  4DX8 A;  3N7C A;  1KZ7 A;  2ZPY A;  4WVF B;  3LJU X;  4HAW B;  1H10 A;  3QIJ A;  3GYP A;  3OAN A;  4KVG B;  2VKI A;  4CHJ A;  1UNP A;  1EAZ A;  2DN6 A;  3ML4 A;  1XX0 A;  2HTH B;  2CY4 A;  2YVC A;  4KAX B;  3AU5 A;  5FI0 A;  2P0F A;  1M7R A;  4DBB A;  3DXC A;  2D9V A;  4K17 A;  3U8Z A;  5KQ1 A;  2J59 M;  5J3Y A;  1UNQ A;  3MPX A;  1OY2 A;  4PQ0 A;  2DKP A;  4MT7 A;  2ELB A;  3KRW A;  4ZRI A;  5FI1 A;  4A6F B;  1FHX A;  2DLW A;  2RNR B;  2COC A;  1N3H A;  1XD4 A;  2ELA A;  1RJ2 A;  1WG7 A;  4NY0 A;  3QBV B;  5DHF B;  4HAU B;  1P6S A;  2EC1 A;  4MY6 A;  3IVF A;  1FOE A;  1U29 A;  2P8V A;  3P7Z A;  3VOQ A;  3DXD A;  4H8S A;  1FHO A;  3TCA A;  4NSW A;  3P6A A;  1X1G A;  2W2X D;  2I1K A;  4HB0 B;  4IFS A;  3TVV A;  2IFS A;  2AL6 A;  1PLS A;  1MPH A;  3FEH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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