1AWEA

Human sos1 pleckstrin homology (ph) domain, nmr, 20 structures
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
130
structure length
130
Chain Sequence
MNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains.
pubmed doi rcsb
molecule tags Signal transduction
source organism Homo sapiens
molecule keywords SOS1
total genus 17
structure length 130
sequence length 130
ec nomenclature
pdb deposition date 1997-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1aweA00
3A8PA 2IFSA 3TCAA 4DXAB 2L1CA 1MK9B 4PQ0A 3FEHA 4A5KA 2YRYA 1OY2A 4K81A 4HAWB 1NI2A 5C5BB 1RRPB 2XQNM 2RLOA 3T06A 1U5GA 2RGNB 3SUZA 3WYFB 5KCVA 1OMWA 3P6AA 1UEFA 1V5UA 2COFA 2Z0OA 4ZRIA 4DBBA 2D10A 4EKUA 1U5FA 2VRWB 1Z87A 2N0YA 2G35A 1B55A 2ADZA 2YT0A 1OQNA 2DKQA 4PNKA 1TQZA 4TKNA 5EFXA 3ZDTA 1X86A 1I7AA 2GJYA 4B6HA 1ZC4B 1BWNA 1U5EA 2P0DA 1PFJA 1BTNA 4YL8A 2UZSA 3DXEA 5L81A 2DKPA 2M38A 3VIAA 2J0KA 5KQ1A 4A6FA 2DHIA 1UPRA 3G9WA 2V76A 2YT1A 1M7EA 2X18A 2YS3A 1TJ6A 2KGXB 3AU5A 1Q67A 2GCLA 5LONB 3KRXA 1V5MA 2LOZA 3RCPA 4HB2B 4CHMA 4IFSA 2E2XA 3GYPA 3QBVB 2YS5A 2MWNB 5DIFB 2MDXA 1AWEA 2COCA 5FI0A 2YF0A 4IOYX 2W2XC 2I5CA 2DX5A 1NTYA 3AU4A 2RVBB 2GS0A 4GMXB 2AL6A 2YS1A 2ELBA 1W1DA 2I5FA 4A6KA 5C5BA 1QC6A 4NY0A 4Z2MB 2EMTA 3QIJA 4K2PA 2K2JA 1X05A 4KHAA 2W2XD 4GZUA 1EF1A 2L2IA 4HB0B 3GYOA 1LW3A 4KAXB 1XKEA 3V5WA 1FGYA 1DROA 2D9VA 3ODOA 5KQ4A 4MT7A 1WI1A 3A98B 2I1JA 4CYEA 3D8DA 5D3VA 2W2WA 1XCGA 2J0MA 2MKRA 3F5RA 5CLQB 1UNPA 2BCJA 3PVWA 5C6RA 4HAZB 4YONA 2DHKA 5DI9B 1V89A 1WVHA 1FOEA 3SNHA 1DDWA 1V88A 2AEHA 2CY5A 2Z0PA 2VSZA 5HE1A 1V61A 4MK0A 3ZVRA 1W1HA 4Z2NA 2K2UA 1Y5OA 2QKMA 4HAYB 2EJ8A 5C16A 1J19A 1X1GA 2Y8GA 5C79A 1MIZB 2P8VA 1H4RA 1SHCA 5CLLB 3DXCA 1WGUA 4A6HA 2N23A 1TXDA 2PZ1A 4HDOA 1AQCA 2NMBA 1UPQA 2D9WA 3HW2B 1X11A 2CODA 1M7RA 4KHOA 5JHGA 2CRFA 5D27A 4BBKA 2R09A 2DYQA 1RJ2A 1U29A 2ZPYA 4IAPA 3PP2A 2M14A 2D2QA 4EJNA 2D9YA 3N7CA 2R0DA 1N3HA 3ULBA 4HAUB 2LYDA 3TO1A 3KSYA 4ZRJA 1FGZA 1XX0A 1MIXA 3HK0A 1J0WA 2P0FA 4HHVA 1XODA 2LOXA 4HAXB 1ZVRA 1U27A 2DHJA 1NU2A 2DLWA 1WG7A 4F7HA 4F7GA 2OTXA 3M1IB 2DA0A 2DTCA 4C0AA 2GCJA 3FM8C 2YSZA 2UZRA 1I2HA 2H7DA 3VOQA 2H7EA 3A8QA 2D9ZA 3KRWA 1PMSA 3FSSA 4K17A 1KZ7A 2JP2A 2Y8FA 2YVCA 4KVGB 1NTVA 2P0HA 1IRSA 4GPTB 2DYNA 1DBHA 4K2OA 5HE2A 4L6EA 1WJMA 3PEGA 1DYNA 1U2BA 4HATB 4XWXA 4A6FB 2K00A 1V5PA 1FHXA 4GN1A 3CXBB 2I1KA 4HB4B 4ZRKA 4H8SA 1GC7A 3ML4A 3U8ZA 1BTKA 5HE3A 2Y7BA 1GC6A 1WGQA 3KY9A 4CHJA 3D8EA 1DDMA 1LB1A 1P3RA 3PVLA 3IVFA 4WVFB 3CIKA 5JLJB 4D0NB 5J3QA 5LOPB 2ELAA 3D8FA 2Z0QA 1FB8A 2D11A 3PG7A 3BINA 4NSWA 2OQBA 2COAA 2VKIA 2IYBA 5DHAB 2CAYA 3TFMA 2RNRB 1SGHA 4HDQA 4Y94A 2DFKA 2D9XA 2FJLA 1E5WA 2LKOA 3MPXA 3TW1A 2EMSA 4GXBA 1K5GB 1P6SA 2LULA 1P5TA 1FAOA 4TYZA 2HE7A 3LJUX 3SYXA 1H10A 4F7UP 3KZ1A 1EAZA 1MKEA 3PZDA 1QQGA 5DH9B 4WJ7A 3ULCA 1W1GA 3U7DA 1UNQA 2KUPA 2CY4A 3SO6A 2QKLA 1WJ1A 1EGXA 3OANA 4P7IA 5D3XA 5DHFB 3WA0A 3ODWA 3TVVA 1ISNA 2HTHB 1XD4A 1KI1B 2DN6A 2MFQA 1MAIA 2ROZB 2UVMA 1FHWA 4KHBB 1KZGA 2KCJA 2DX1A 1U5DA 2ROVA 1XR0B 2RUKB 4GMVA 1FHOA 3P7ZA 5HE0A 4EMOA 2D4QA 3HQCA 3ODXA 2RSGA 1BAKA 4MY6A 1DDVA 1GG3A 2J59M 5FI1A 1X1FA 5JP4A 5JHHA 2EC1A 1ZSQA 5J3YA 4HAVB 3UZTA 3SV1A 3X23A 2Q13A 1UNRA 5D3WA 3QWMA 4HB3B 4WSFA 2J0JA 5J3TA 4DX8A 1MPHA 3NSUA 1EVHA 1Y19B 2LG1A 3F0WA 3PVUA 3BJIA 3DXDA 5GOWB 1ZC3B 2NZ8B 1ZM0A 3MDBC 5D3YA 1K5DB 1PLSA 3PSCA 4DX90 3AJ4A 1MK7B 3O96A
chains in the Genus database with same CATH superfamily
3A8PA 2IFSA 2R2YA 3TCAA 4DXAB 2L1CA 1MK9B 4PQ0A 3FEHA 5I2MA 4GOUA 4A5KA 2YRYA 1OY2A 4K81A 4HAWB 1NI2A 5C5BB 1RRPB 2XQNM 2RLOA 3T06A 1U5GA 2RGNB 4KHBA 3SUZA 3WYFB 5KCVA 1OMWA 3P6AA 1UEFA 1V5UA 2COFA 2Z0OA 4ZRIA 4DBBA 2D10A 4EKUA 1U5FA 2VRWB 1Z87A 2N0YA 2G35A 1B55A 2ADZA 2K49A 2YT0A 1OQNA 2DKQA 4PNKA 1TQZA 4TKNA 5EFXA 3ZDTA 1X86A 1I7AA 1MI1A 2GJYA 4L1RA 4B6HA 1ZC4B 1BWNA 1U5EA 2P0DA 1PFJA 1BTNA 4YL8A 2UZSA 3DXEA 4QXAB 5L81A 2DKPA 2M38A 3B77A 3VIAA 2J0KA 5KQ1A 4A6FA 2DHIA 1UPRA 3G9WA 2V76A 2YT1A 3HSAA 1M7EA 2X18A 2YS3A 1TJ6A 2KGXB 3AU5A 1Q67A 2GCLA 5LONB 3KRXA 1V5MA 2LOZA 3RCPA 4HB2B 4CHMA 4IFSA 2E2XA 3GYPA 3QBVB 5IRSA 2YS5A 2MWNB 5DIFB 2MDXA 1AWEA 2COCA 5FI0A 2YF0A 4IOYX 2W2XC 2I5CA 2DX5A 5LG4B 1NTYA 3AU4A 2RVBB 2GS0A 4GMXB 2AL6A 2YS1A 2ELBA 4CSQA 1W1DA 2I5FA 4A6KA 5C5BA 1QC6A 4NY0A 4Z2MB 2EMTA 3QIJA 4K2PA 2K2JA 1X05A 4KHAA 2W2XD 4GZUA 1EF1A 2L2IA 4HB0B 3GYOA 1LW3A 4KAXB 1XKEA 2KUQA 3V5WA 1FGYA 1DROA 2D9VA 3ODOA 2YT2A 5KQ4A 4MT7A 1WI1A 2NBVA 3A98B 2I1JA 4CYEA 3D8DA 5D3VA 2W2WA 1XCGA 2J0MA 2MKRA 3F5RA 5CLQB 1UNPA 2BCJA 3PVWA 5C6RA 4HAZB 4YONA 3HIEA 2DHKA 5DI9B 1V89A 1WVHA 1FOEA 3SNHA 1DDWA 1V88A 1T77A 2AEHA 2CY5A 2ZKMX 2Z0PA 2VSZA 5HE1A 1V61A 4MK0A 3ZVRA 2RRFA 1W1HA 4Z2NA 2K2UA 1Y5OA 2QKMA 4HAYB 2EJ8A 5C16A 1J19A 1X1GA 2Y8GA 5C79A 1MIZB 2P8VA 1H4RA 1SHCA 5CLLB 3DXCA 1WGUA 4A6HA 2N23A 1TXDA 2PZ1A 4HDOA 1AQCA 2NMBA 1UPQA 2D9WA 3HW2B 1X11A 2CODA 1M7RA 4KHOA 5JHGA 2CRFA 5D27A 3A58A 4BBKA 2R09A 2DYQA 2KIEA 1RJ2A 1U29A 1ZYIA 2ZPYA 4IAPA 3PP2A 2M14A 2D2QA 4EJNA 2D9YA 3N7CA 2R0DA 3NW8A 1N3HA 3ULBA 3NWDA 4HAUB 2LYDA 3TO1A 3KSYA 2Z14A 4ZRJA 1FGZA 1XX0A 1MIXA 3HK0A 1J0WA 2P0FA 4GNKB 4HHVA 1XODA 2LOXA 4HAXB 1ZVRA 1U27A 2DHJA 1NU2A 2DLWA 1WG7A 2K8EA 3OHMB 4F7HA 4F7GA 2OTXA 3M1IB 2DA0A 2DTCA 4C0AA 2GCJA 3FM8C 3U12A 2YSZA 2UZRA 1I2HA 2H7DA 3VOQA 2H7EA 3A8QA 2D9ZA 3KRWA 1PMSA 3FSSA 4K17A 1KZ7A 2JP2A 2Y8FA 2YVCA 4KVGB 4QJ5B 1NTVA 2P0HA 1IRSA 4GPTB 2DYNA 3NWFA 1DBHA 4K2OA 5HE2A 4L6EA 1WJMA 3PEGA 1DYNA 1U2BA 4HATB 4XWXA 4A6FB 2KIGA 2K00A 1V5PA 1FHXA 4GN1A 3CXBB 2I1KA 4HB4B 4ZRKA 4H8SA 1GC7A 3ML4A 3U8ZA 1BTKA 2Z59A 5HE3A 2Y7BA 4QJ4B 1GC6A 1WGQA 3KY9A 4HSIA 4CHJA 3D8EA 1DDMA 1LB1A 1P3RA 3PVLA 3IVFA 4WVFB 3CIKA 5JLJB 2Z4DA 4D0NB 5J3QA 5LOPB 2ELAA 3D8FA 2Z0QA 1FB8A 4QJ3B 2D11A 3PG7A 3BINA 4NSWA 2OQBA 5M4YB 2COAA 2VKIA 2IYBA 5DHAB 2CAYA 3TFMA 2RNRB 3FVCA 1SGHA 4HDQA 4Y94A 2DFKA 2D9XA 2FJLA 1E5WA 2LKOA 3MPXA 3TW1A 2Z13A 2EMSA 4GXBA 1K5GB 1P6SA 2LULA 1P5TA 1FAOA 4TYZA 2HE7A 3LJUX 3SYXA 1H10A 4DIXA 3KZ1A 1EAZA 4F7UP 1MKEA 3PZDA 1QQGA 5DH9B 4WJ7A 3ULCA 1W1GA 3U7DA 5I2SA 1UNQA 4OSNA 2KUPA 2CY4A 2FJUB 3SO6A 2QKLA 1WJ1A 1EGXA 3OANA 4P7IA 5D3XA 5DHFB 3WA0A 3ODWA 3TVVA 2KR0A 1ISNA 2HTHB 1XD4A 1KI1B 2DN6A 2MFQA 1MAIA 2ROZB 2UVMA 4D6WA 1FHWA 4KHBB 1KZGA 2KCJA 2DX1A 1U5DA 2ROVA 1XR0B 2RUKB 4GMVA 1FHOA 3P7ZA 5HE0A 3DCXA 4EMOA 2D4QA 2GUMA 3HQCA 3ODXA 2RSGA 1BAKA 4MY6A 1DDVA 1GG3A 2J59M 5FI1A 1X1FA 5JP4A 5JHHA 2EC1A 1ZSQA 5J3YA 4HAVB 3NWAA 4OT1A 3UZTA 3SV1A 3X23A 2Q13A 1UNRA 5D3WA 3QWMA 4HB3B 4WSFA 2J0JA 5J3TA 4DX8A 1MPHA 3NSUA 1EVHA 1Y19B 2LG1A 3F0WA 3PVUA 3BJIA 3DXDA 5GOWB 1ZC3B 2NZ8B 1ZM0A 3MDBC 5D3YA 1K5DB 1PLSA 3PSCA 4DX90 3AJ4A 1MK7B 3O96A
chains in the Genus database with same CATH topology
3A8PA 2IFSA 3TCAA 4DXAB 2L1CA 1MK9B 4PQ0A 3FEHA 4A5KA 2YRYA 1OY2A 4K81A 4HAWB 1NI2A 5C5BB 1RRPB 2XQNM 2RLOA 3T06A 1U5GA 2RGNB 3SUZA 3WYFB 5KCVA 1OMWA 3P6AA 1UEFA 1V5UA 2COFA 2Z0OA 4ZRIA 4DBBA 2D10A 4EKUA 1U5FA 2VRWB 1Z87A 2N0YA 2G35A 1B55A 2ADZA 2YT0A 1OQNA 2DKQA 4PNKA 1TQZA 4TKNA 5EFXA 3ZDTA 1X86A 1I7AA 2GJYA 4B6HA 1ZC4B 1BWNA 1U5EA 2P0DA 1PFJA 1BTNA 4YL8A 2UZSA 3DXEA 5L81A 2DKPA 2M38A 3VIAA 2J0KA 5KQ1A 4A6FA 2DHIA 1UPRA 3G9WA 2V76A 2YT1A 1M7EA 2X18A 2YS3A 1TJ6A 2KGXB 3AU5A 1Q67A 2GCLA 5LONB 3KRXA 1V5MA 2LOZA 3RCPA 4HB2B 4CHMA 4IFSA 2E2XA 3GYPA 3QBVB 2YS5A 2MWNB 5DIFB 2MDXA 1AWEA 2COCA 5FI0A 2YF0A 4IOYX 2W2XC 2I5CA 2DX5A 1NTYA 3AU4A 2RVBB 2GS0A 4GMXB 2AL6A 2YS1A 2ELBA 1W1DA 2I5FA 4A6KA 5C5BA 1QC6A 4NY0A 4Z2MB 2EMTA 3QIJA 4K2PA 2K2JA 1X05A 4KHAA 2W2XD 4GZUA 1EF1A 2L2IA 4HB0B 3GYOA 1LW3A 4KAXB 1XKEA 3V5WA 1FGYA 1DROA 2D9VA 3ODOA 5KQ4A 4MT7A 1WI1A 3A98B 2I1JA 4CYEA 3D8DA 5D3VA 2W2WA 1XCGA 2J0MA 2MKRA 3F5RA 5CLQB 1UNPA 2BCJA 3PVWA 5C6RA 4HAZB 4YONA 2DHKA 5DI9B 1V89A 1WVHA 1FOEA 3SNHA 1DDWA 1V88A 2AEHA 2CY5A 2Z0PA 2VSZA 5HE1A 1V61A 4MK0A 3ZVRA 1W1HA 4Z2NA 2K2UA 1Y5OA 2QKMA 4HAYB 2EJ8A 5C16A 1J19A 1X1GA 2Y8GA 5C79A 1MIZB 2P8VA 1H4RA 1SHCA 5CLLB 3DXCA 1WGUA 4A6HA 2N23A 1TXDA 2PZ1A 4HDOA 1AQCA 2NMBA 1UPQA 2D9WA 3HW2B 1X11A 2CODA 1M7RA 4KHOA 5JHGA 2CRFA 5D27A 4BBKA 2R09A 2DYQA 1RJ2A 1U29A 2ZPYA 4IAPA 3PP2A 2M14A 2D2QA 4EJNA 2D9YA 3N7CA 2R0DA 1N3HA 3ULBA 4HAUB 2LYDA 3TO1A 3KSYA 4ZRJA 1FGZA 1XX0A 1MIXA 3HK0A 1J0WA 2P0FA 4HHVA 1XODA 2LOXA 4HAXB 1ZVRA 1U27A 2DHJA 1NU2A 2DLWA 1WG7A 4F7HA 4F7GA 2OTXA 3M1IB 2DA0A 2DTCA 4C0AA 2GCJA 3FM8C 2YSZA 2UZRA 1I2HA 2H7DA 3VOQA 2H7EA 3A8QA 2D9ZA 3KRWA 1PMSA 3FSSA 4K17A 1KZ7A 2JP2A 2Y8FA 2YVCA 4KVGB 1NTVA 2P0HA 1IRSA 4GPTB 2DYNA 1DBHA 4K2OA 5HE2A 4L6EA 1WJMA 3PEGA 1DYNA 1U2BA 4HATB 4XWXA 4A6FB 2K00A 1V5PA 1FHXA 4GN1A 3CXBB 2I1KA 4HB4B 4ZRKA 4H8SA 1GC7A 3ML4A 3U8ZA 1BTKA 5HE3A 2Y7BA 1GC6A 1WGQA 3KY9A 4CHJA 3D8EA 1DDMA 1LB1A 1P3RA 3PVLA 3IVFA 4WVFB 3CIKA 5JLJB 4D0NB 5J3QA 5LOPB 2ELAA 3D8FA 2Z0QA 1FB8A 2D11A 3PG7A 3BINA 4NSWA 2OQBA 2COAA 2VKIA 2IYBA 5DHAB 2CAYA 3TFMA 2RNRB 1SGHA 4HDQA 4Y94A 2DFKA 2D9XA 2FJLA 1E5WA 2LKOA 3MPXA 3TW1A 2EMSA 4GXBA 1K5GB 1P6SA 2LULA 1P5TA 1FAOA 4TYZA 2HE7A 3LJUX 3SYXA 1H10A 4F7UP 3KZ1A 1EAZA 1MKEA 3PZDA 1QQGA 5DH9B 4WJ7A 3ULCA 1W1GA 3U7DA 1UNQA 2KUPA 2CY4A 3SO6A 2QKLA 1WJ1A 1EGXA 3OANA 4P7IA 5D3XA 5DHFB 3WA0A 3ODWA 3TVVA 1ISNA 2HTHB 1XD4A 1KI1B 2DN6A 2MFQA 1MAIA 2ROZB 2UVMA 1FHWA 4KHBB 1KZGA 2KCJA 2DX1A 1U5DA 2ROVA 1XR0B 2RUKB 4GMVA 1FHOA 3P7ZA 5HE0A 4EMOA 2D4QA 3HQCA 3ODXA 2RSGA 1BAKA 4MY6A 1DDVA 1GG3A 2J59M 5FI1A 1X1FA 5JP4A 5JHHA 2EC1A 1ZSQA 5J3YA 4HAVB 3UZTA 3SV1A 3X23A 2Q13A 1UNRA 5D3WA 3QWMA 4HB3B 4WSFA 2J0JA 5J3TA 4DX8A 1MPHA 3NSUA 1EVHA 1Y19B 2LG1A 3F0WA 3PVUA 3BJIA 3DXDA 5GOWB 1ZC3B 2NZ8B 1ZM0A 3MDBC 5D3YA 1K5DB 1PLSA 3PSCA 4DX90 3AJ4A 1MK7B 3O96A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3A8P A;  2IFS A;  3TCA A;  4DXA B;  2L1C A;  1MK9 B;  4PQ0 A;  3FEH A;  4A5K A;  2YRY A;  1OY2 A;  4K81 A;  4HAW B;  1NI2 A;  5C5B B;  1RRP B;  2XQN M;  2RLO A;  3T06 A;  1U5G A;  2RGN B;  3SUZ A;  3WYF B;  5KCV A;  1OMW A;  3P6A A;  1UEF A;  1V5U A;  2COF A;  2Z0O A;  4ZRI A;  4DBB A;  2D10 A;  4EKU A;  1U5F A;  2VRW B;  1Z87 A;  2N0Y A;  2G35 A;  1B55 A;  2ADZ A;  2YT0 A;  1OQN A;  2DKQ A;  4PNK A;  1TQZ A;  4TKN A;  5EFX A;  3ZDT A;  1X86 A;  1I7A A;  2GJY A;  4B6H A;  1ZC4 B;  1BWN A;  1U5E A;  2P0D A;  1PFJ A;  1BTN A;  4YL8 A;  2UZS A;  3DXE A;  5L81 A;  2DKP A;  2M38 A;  3VIA A;  2J0K A;  5KQ1 A;  4A6F A;  2DHI A;  1UPR A;  3G9W A;  2V76 A;  2YT1 A;  1M7E A;  2X18 A;  2YS3 A;  1TJ6 A;  2KGX B;  3AU5 A;  1Q67 A;  2GCL A;  5LON B;  3KRX A;  1V5M A;  2LOZ A;  3RCP A;  4HB2 B;  4CHM A;  4IFS A;  2E2X A;  3GYP A;  3QBV B;  2YS5 A;  2MWN B;  5DIF B;  2MDX A;  1AWE A;  2COC A;  5FI0 A;  2YF0 A;  4IOY X;  2W2X C;  2I5C A;  2DX5 A;  1NTY A;  3AU4 A;  2RVB B;  2GS0 A;  4GMX B;  2AL6 A;  2YS1 A;  2ELB A;  1W1D A;  2I5F A;  4A6K A;  5C5B A;  1QC6 A;  4NY0 A;  4Z2M B;  2EMT A;  3QIJ A;  4K2P A;  2K2J A;  1X05 A;  4KHA A;  2W2X D;  4GZU A;  1EF1 A;  2L2I A;  4HB0 B;  3GYO A;  1LW3 A;  4KAX B;  1XKE A;  3V5W A;  1FGY A;  1DRO A;  2D9V A;  3ODO A;  5KQ4 A;  4MT7 A;  1WI1 A;  3A98 B;  2I1J A;  4CYE A;  3D8D A;  5D3V A;  2W2W A;  1XCG A;  2J0M A;  2MKR A;  3F5R A;  5CLQ B;  1UNP A;  2BCJ A;  3PVW A;  5C6R A;  4HAZ B;  4YON A;  2DHK A;  5DI9 B;  1V89 A;  1WVH A;  1FOE A;  3SNH A;  1DDW A;  1V88 A;  2AEH A;  2CY5 A;  2Z0P A;  2VSZ A;  5HE1 A;  1V61 A;  4MK0 A;  3ZVR A;  1W1H A;  4Z2N A;  2K2U A;  1Y5O A;  2QKM A;  4HAY B;  2EJ8 A;  5C16 A;  1J19 A;  1X1G A;  2Y8G A;  5C79 A;  1MIZ B;  2P8V A;  1H4R A;  1SHC A;  5CLL B;  3DXC A;  1WGU A;  4A6H A;  2N23 A;  1TXD A;  2PZ1 A;  4HDO A;  1AQC A;  2NMB A;  1UPQ A;  2D9W A;  3HW2 B;  1X11 A;  2COD A;  1M7R A;  4KHO A;  5JHG A;  2CRF A;  5D27 A;  4BBK A;  2R09 A;  2DYQ A;  1RJ2 A;  1U29 A;  2ZPY A;  4IAP A;  3PP2 A;  2M14 A;  2D2Q A;  4EJN A;  2D9Y A;  3N7C A;  2R0D A;  1N3H A;  3ULB A;  4HAU B;  2LYD A;  3TO1 A;  3KSY A;  4ZRJ A;  1FGZ A;  1XX0 A;  1MIX A;  3HK0 A;  1J0W A;  2P0F A;  4HHV A;  1XOD A;  2LOX A;  4HAX B;  1ZVR A;  1U27 A;  2DHJ A;  1NU2 A;  2DLW A;  1WG7 A;  4F7H A;  4F7G A;  2OTX A;  3M1I B;  2DA0 A;  2DTC A;  4C0A A;  2GCJ A;  3FM8 C;  2YSZ A;  2UZR A;  1I2H A;  2H7D A;  3VOQ A;  2H7E A;  3A8Q A;  2D9Z A;  3KRW A;  1PMS A;  3FSS A;  4K17 A;  1KZ7 A;  2JP2 A;  2Y8F A;  2YVC A;  4KVG B;  1NTV A;  2P0H A;  1IRS A;  4GPT B;  2DYN A;  1DBH A;  4K2O A;  5HE2 A;  4L6E A;  1WJM A;  3PEG A;  1DYN A;  1U2B A;  4HAT B;  4XWX A;  4A6F B;  2K00 A;  1V5P A;  1FHX A;  4GN1 A;  3CXB B;  2I1K A;  4HB4 B;  4ZRK A;  4H8S A;  1GC7 A;  3ML4 A;  3U8Z A;  1BTK A;  5HE3 A;  2Y7B A;  1GC6 A;  1WGQ A;  3KY9 A;  4CHJ A;  3D8E A;  1DDM A;  1LB1 A;  1P3R A;  3PVL A;  3IVF A;  4WVF B;  3CIK A;  5JLJ B;  4D0N B;  5J3Q A;  5LOP B;  2ELA A;  3D8F A;  2Z0Q A;  1FB8 A;  2D11 A;  3PG7 A;  3BIN A;  4NSW A;  2OQB A;  2COA A;  2VKI A;  2IYB A;  5DHA B;  2CAY A;  3TFM A;  2RNR B;  1SGH A;  4HDQ A;  4Y94 A;  2DFK A;  2D9X A;  2FJL A;  1E5W A;  2LKO A;  3MPX A;  3TW1 A;  2EMS A;  4GXB A;  1K5G B;  1P6S A;  2LUL A;  1P5T A;  1FAO A;  4TYZ A;  2HE7 A;  3LJU X;  3SYX A;  1H10 A;  4F7U P;  3KZ1 A;  1EAZ A;  1MKE A;  3PZD A;  1QQG A;  5DH9 B;  4WJ7 A;  3ULC A;  1W1G A;  3U7D A;  1UNQ A;  2KUP A;  2CY4 A;  3SO6 A;  2QKL A;  1WJ1 A;  1EGX A;  3OAN A;  4P7I A;  5D3X A;  5DHF B;  3WA0 A;  3ODW A;  3TVV A;  1ISN A;  2HTH B;  1XD4 A;  1KI1 B;  2DN6 A;  2MFQ A;  1MAI A;  2ROZ B;  2UVM A;  1FHW A;  4KHB B;  1KZG A;  2KCJ A;  2DX1 A;  1U5D A;  2ROV A;  1XR0 B;  2RUK B;  4GMV A;  1FHO A;  3P7Z A;  5HE0 A;  4EMO A;  2D4Q A;  3HQC A;  3ODX A;  2RSG A;  1BAK A;  4MY6 A;  1DDV A;  1GG3 A;  2J59 M;  5FI1 A;  1X1F A;  5JP4 A;  5JHH A;  2EC1 A;  1ZSQ A;  5J3Y A;  4HAV B;  3UZT A;  3SV1 A;  3X23 A;  2Q13 A;  1UNR A;  5D3W A;  3QWM A;  4HB3 B;  4WSF A;  2J0J A;  5J3T A;  4DX8 A;  1MPH A;  3NSU A;  1EVH A;  1Y19 B;  2LG1 A;  3F0W A;  3PVU A;  3BJI A;  3DXD A;  5GOW B;  1ZC3 B;  2NZ8 B;  1ZM0 A;  3MDB C;  5D3Y A;  1K5D B;  1PLS A;  3PSC A;  4DX9 0;  3AJ4 A;  1MK7 B;  3O96 A; 
#chains in the Genus database with same CATH topology
 3A8P A;  2IFS A;  2R2Y A;  3TCA A;  4DXA B;  2L1C A;  1MK9 B;  4PQ0 A;  3FEH A;  5I2M A;  4GOU A;  4A5K A;  2YRY A;  1OY2 A;  4K81 A;  4HAW B;  1NI2 A;  5C5B B;  1RRP B;  2XQN M;  2RLO A;  3T06 A;  1U5G A;  2RGN B;  4KHB A;  3SUZ A;  3WYF B;  5KCV A;  1OMW A;  3P6A A;  1UEF A;  1V5U A;  2COF A;  2Z0O A;  4ZRI A;  4DBB A;  2D10 A;  4EKU A;  1U5F A;  2VRW B;  1Z87 A;  2N0Y A;  2G35 A;  1B55 A;  2ADZ A;  2K49 A;  2YT0 A;  1OQN A;  2DKQ A;  4PNK A;  1TQZ A;  4TKN A;  5EFX A;  3ZDT A;  1X86 A;  1I7A A;  1MI1 A;  2GJY A;  4L1R A;  4B6H A;  1ZC4 B;  1BWN A;  1U5E A;  2P0D A;  1PFJ A;  1BTN A;  4YL8 A;  2UZS A;  3DXE A;  4QXA B;  5L81 A;  2DKP A;  2M38 A;  3B77 A;  3VIA A;  2J0K A;  5KQ1 A;  4A6F A;  2DHI A;  1UPR A;  3G9W A;  2V76 A;  2YT1 A;  3HSA A;  1M7E A;  2X18 A;  2YS3 A;  1TJ6 A;  2KGX B;  3AU5 A;  1Q67 A;  2GCL A;  5LON B;  3KRX A;  1V5M A;  2LOZ A;  3RCP A;  4HB2 B;  4CHM A;  4IFS A;  2E2X A;  3GYP A;  3QBV B;  5IRS A;  2YS5 A;  2MWN B;  5DIF B;  2MDX A;  1AWE A;  2COC A;  5FI0 A;  2YF0 A;  4IOY X;  2W2X C;  2I5C A;  2DX5 A;  5LG4 B;  1NTY A;  3AU4 A;  2RVB B;  2GS0 A;  4GMX B;  2AL6 A;  2YS1 A;  2ELB A;  4CSQ A;  1W1D A;  2I5F A;  4A6K A;  5C5B A;  1QC6 A;  4NY0 A;  4Z2M B;  2EMT A;  3QIJ A;  4K2P A;  2K2J A;  1X05 A;  4KHA A;  2W2X D;  4GZU A;  1EF1 A;  2L2I A;  4HB0 B;  3GYO A;  1LW3 A;  4KAX B;  1XKE A;  2KUQ A;  3V5W A;  1FGY A;  1DRO A;  2D9V A;  3ODO A;  2YT2 A;  5KQ4 A;  4MT7 A;  1WI1 A;  2NBV A;  3A98 B;  2I1J A;  4CYE A;  3D8D A;  5D3V A;  2W2W A;  1XCG A;  2J0M A;  2MKR A;  3F5R A;  5CLQ B;  1UNP A;  2BCJ A;  3PVW A;  5C6R A;  4HAZ B;  4YON A;  3HIE A;  2DHK A;  5DI9 B;  1V89 A;  1WVH A;  1FOE A;  3SNH A;  1DDW A;  1V88 A;  1T77 A;  2AEH A;  2CY5 A;  2ZKM X;  2Z0P A;  2VSZ A;  5HE1 A;  1V61 A;  4MK0 A;  3ZVR A;  2RRF A;  1W1H A;  4Z2N A;  2K2U A;  1Y5O A;  2QKM A;  4HAY B;  2EJ8 A;  5C16 A;  1J19 A;  1X1G A;  2Y8G A;  5C79 A;  1MIZ B;  2P8V A;  1H4R A;  1SHC A;  5CLL B;  3DXC A;  1WGU A;  4A6H A;  2N23 A;  1TXD A;  2PZ1 A;  4HDO A;  1AQC A;  2NMB A;  1UPQ A;  2D9W A;  3HW2 B;  1X11 A;  2COD A;  1M7R A;  4KHO A;  5JHG A;  2CRF A;  5D27 A;  3A58 A;  4BBK A;  2R09 A;  2DYQ A;  2KIE A;  1RJ2 A;  1U29 A;  1ZYI A;  2ZPY A;  4IAP A;  3PP2 A;  2M14 A;  2D2Q A;  4EJN A;  2D9Y A;  3N7C A;  2R0D A;  3NW8 A;  1N3H A;  3ULB A;  3NWD A;  4HAU B;  2LYD A;  3TO1 A;  3KSY A;  2Z14 A;  4ZRJ A;  1FGZ A;  1XX0 A;  1MIX A;  3HK0 A;  1J0W A;  2P0F A;  4GNK B;  4HHV A;  1XOD A;  2LOX A;  4HAX B;  1ZVR A;  1U27 A;  2DHJ A;  1NU2 A;  2DLW A;  1WG7 A;  2K8E A;  3OHM B;  4F7H A;  4F7G A;  2OTX A;  3M1I B;  2DA0 A;  2DTC A;  4C0A A;  2GCJ A;  3FM8 C;  3U12 A;  2YSZ A;  2UZR A;  1I2H A;  2H7D A;  3VOQ A;  2H7E A;  3A8Q A;  2D9Z A;  3KRW A;  1PMS A;  3FSS A;  4K17 A;  1KZ7 A;  2JP2 A;  2Y8F A;  2YVC A;  4KVG B;  4QJ5 B;  1NTV A;  2P0H A;  1IRS A;  4GPT B;  2DYN A;  3NWF A;  1DBH A;  4K2O A;  5HE2 A;  4L6E A;  1WJM A;  3PEG A;  1DYN A;  1U2B A;  4HAT B;  4XWX A;  4A6F B;  2KIG A;  2K00 A;  1V5P A;  1FHX A;  4GN1 A;  3CXB B;  2I1K A;  4HB4 B;  4ZRK A;  4H8S A;  1GC7 A;  3ML4 A;  3U8Z A;  1BTK A;  2Z59 A;  5HE3 A;  2Y7B A;  4QJ4 B;  1GC6 A;  1WGQ A;  3KY9 A;  4HSI A;  4CHJ A;  3D8E A;  1DDM A;  1LB1 A;  1P3R A;  3PVL A;  3IVF A;  4WVF B;  3CIK A;  5JLJ B;  2Z4D A;  4D0N B;  5J3Q A;  5LOP B;  2ELA A;  3D8F A;  2Z0Q A;  1FB8 A;  4QJ3 B;  2D11 A;  3PG7 A;  3BIN A;  4NSW A;  2OQB A;  5M4Y B;  2COA A;  2VKI A;  2IYB A;  5DHA B;  2CAY A;  3TFM A;  2RNR B;  3FVC A;  1SGH A;  4HDQ A;  4Y94 A;  2DFK A;  2D9X A;  2FJL A;  1E5W A;  2LKO A;  3MPX A;  3TW1 A;  2Z13 A;  2EMS A;  4GXB A;  1K5G B;  1P6S A;  2LUL A;  1P5T A;  1FAO A;  4TYZ A;  2HE7 A;  3LJU X;  3SYX A;  1H10 A;  4DIX A;  3KZ1 A;  1EAZ A;  4F7U P;  1MKE A;  3PZD A;  1QQG A;  5DH9 B;  4WJ7 A;  3ULC A;  1W1G A;  3U7D A;  5I2S A;  1UNQ A;  4OSN A;  2KUP A;  2CY4 A;  2FJU B;  3SO6 A;  2QKL A;  1WJ1 A;  1EGX A;  3OAN A;  4P7I A;  5D3X A;  5DHF B;  3WA0 A;  3ODW A;  3TVV A;  2KR0 A;  1ISN A;  2HTH B;  1XD4 A;  1KI1 B;  2DN6 A;  2MFQ A;  1MAI A;  2ROZ B;  2UVM A;  4D6W A;  1FHW A;  4KHB B;  1KZG A;  2KCJ A;  2DX1 A;  1U5D A;  2ROV A;  1XR0 B;  2RUK B;  4GMV A;  1FHO A;  3P7Z A;  5HE0 A;  3DCX A;  4EMO A;  2D4Q A;  2GUM A;  3HQC A;  3ODX A;  2RSG A;  1BAK A;  4MY6 A;  1DDV A;  1GG3 A;  2J59 M;  5FI1 A;  1X1F A;  5JP4 A;  5JHH A;  2EC1 A;  1ZSQ A;  5J3Y A;  4HAV B;  3NWA A;  4OT1 A;  3UZT A;  3SV1 A;  3X23 A;  2Q13 A;  1UNR A;  5D3W A;  3QWM A;  4HB3 B;  4WSF A;  2J0J A;  5J3T A;  4DX8 A;  1MPH A;  3NSU A;  1EVH A;  1Y19 B;  2LG1 A;  3F0W A;  3PVU A;  3BJI A;  3DXD A;  5GOW B;  1ZC3 B;  2NZ8 B;  1ZM0 A;  3MDB C;  5D3Y A;  1K5D B;  1PLS A;  3PSC A;  4DX9 0;  3AJ4 A;  1MK7 B;  3O96 A; 
#chains in the Genus database with same CATH homology
 3A8P A;  2IFS A;  3TCA A;  4DXA B;  2L1C A;  1MK9 B;  4PQ0 A;  3FEH A;  4A5K A;  2YRY A;  1OY2 A;  4K81 A;  4HAW B;  1NI2 A;  5C5B B;  1RRP B;  2XQN M;  2RLO A;  3T06 A;  1U5G A;  2RGN B;  3SUZ A;  3WYF B;  5KCV A;  1OMW A;  3P6A A;  1UEF A;  1V5U A;  2COF A;  2Z0O A;  4ZRI A;  4DBB A;  2D10 A;  4EKU A;  1U5F A;  2VRW B;  1Z87 A;  2N0Y A;  2G35 A;  1B55 A;  2ADZ A;  2YT0 A;  1OQN A;  2DKQ A;  4PNK A;  1TQZ A;  4TKN A;  5EFX A;  3ZDT A;  1X86 A;  1I7A A;  2GJY A;  4B6H A;  1ZC4 B;  1BWN A;  1U5E A;  2P0D A;  1PFJ A;  1BTN A;  4YL8 A;  2UZS A;  3DXE A;  5L81 A;  2DKP A;  2M38 A;  3VIA A;  2J0K A;  5KQ1 A;  4A6F A;  2DHI A;  1UPR A;  3G9W A;  2V76 A;  2YT1 A;  1M7E A;  2X18 A;  2YS3 A;  1TJ6 A;  2KGX B;  3AU5 A;  1Q67 A;  2GCL A;  5LON B;  3KRX A;  1V5M A;  2LOZ A;  3RCP A;  4HB2 B;  4CHM A;  4IFS A;  2E2X A;  3GYP A;  3QBV B;  2YS5 A;  2MWN B;  5DIF B;  2MDX A;  1AWE A;  2COC A;  5FI0 A;  2YF0 A;  4IOY X;  2W2X C;  2I5C A;  2DX5 A;  1NTY A;  3AU4 A;  2RVB B;  2GS0 A;  4GMX B;  2AL6 A;  2YS1 A;  2ELB A;  1W1D A;  2I5F A;  4A6K A;  5C5B A;  1QC6 A;  4NY0 A;  4Z2M B;  2EMT A;  3QIJ A;  4K2P A;  2K2J A;  1X05 A;  4KHA A;  2W2X D;  4GZU A;  1EF1 A;  2L2I A;  4HB0 B;  3GYO A;  1LW3 A;  4KAX B;  1XKE A;  3V5W A;  1FGY A;  1DRO A;  2D9V A;  3ODO A;  5KQ4 A;  4MT7 A;  1WI1 A;  3A98 B;  2I1J A;  4CYE A;  3D8D A;  5D3V A;  2W2W A;  1XCG A;  2J0M A;  2MKR A;  3F5R A;  5CLQ B;  1UNP A;  2BCJ A;  3PVW A;  5C6R A;  4HAZ B;  4YON A;  2DHK A;  5DI9 B;  1V89 A;  1WVH A;  1FOE A;  3SNH A;  1DDW A;  1V88 A;  2AEH A;  2CY5 A;  2Z0P A;  2VSZ A;  5HE1 A;  1V61 A;  4MK0 A;  3ZVR A;  1W1H A;  4Z2N A;  2K2U A;  1Y5O A;  2QKM A;  4HAY B;  2EJ8 A;  5C16 A;  1J19 A;  1X1G A;  2Y8G A;  5C79 A;  1MIZ B;  2P8V A;  1H4R A;  1SHC A;  5CLL B;  3DXC A;  1WGU A;  4A6H A;  2N23 A;  1TXD A;  2PZ1 A;  4HDO A;  1AQC A;  2NMB A;  1UPQ A;  2D9W A;  3HW2 B;  1X11 A;  2COD A;  1M7R A;  4KHO A;  5JHG A;  2CRF A;  5D27 A;  4BBK A;  2R09 A;  2DYQ A;  1RJ2 A;  1U29 A;  2ZPY A;  4IAP A;  3PP2 A;  2M14 A;  2D2Q A;  4EJN A;  2D9Y A;  3N7C A;  2R0D A;  1N3H A;  3ULB A;  4HAU B;  2LYD A;  3TO1 A;  3KSY A;  4ZRJ A;  1FGZ A;  1XX0 A;  1MIX A;  3HK0 A;  1J0W A;  2P0F A;  4HHV A;  1XOD A;  2LOX A;  4HAX B;  1ZVR A;  1U27 A;  2DHJ A;  1NU2 A;  2DLW A;  1WG7 A;  4F7H A;  4F7G A;  2OTX A;  3M1I B;  2DA0 A;  2DTC A;  4C0A A;  2GCJ A;  3FM8 C;  2YSZ A;  2UZR A;  1I2H A;  2H7D A;  3VOQ A;  2H7E A;  3A8Q A;  2D9Z A;  3KRW A;  1PMS A;  3FSS A;  4K17 A;  1KZ7 A;  2JP2 A;  2Y8F A;  2YVC A;  4KVG B;  1NTV A;  2P0H A;  1IRS A;  4GPT B;  2DYN A;  1DBH A;  4K2O A;  5HE2 A;  4L6E A;  1WJM A;  3PEG A;  1DYN A;  1U2B A;  4HAT B;  4XWX A;  4A6F B;  2K00 A;  1V5P A;  1FHX A;  4GN1 A;  3CXB B;  2I1K A;  4HB4 B;  4ZRK A;  4H8S A;  1GC7 A;  3ML4 A;  3U8Z A;  1BTK A;  5HE3 A;  2Y7B A;  1GC6 A;  1WGQ A;  3KY9 A;  4CHJ A;  3D8E A;  1DDM A;  1LB1 A;  1P3R A;  3PVL A;  3IVF A;  4WVF B;  3CIK A;  5JLJ B;  4D0N B;  5J3Q A;  5LOP B;  2ELA A;  3D8F A;  2Z0Q A;  1FB8 A;  2D11 A;  3PG7 A;  3BIN A;  4NSW A;  2OQB A;  2COA A;  2VKI A;  2IYB A;  5DHA B;  2CAY A;  3TFM A;  2RNR B;  1SGH A;  4HDQ A;  4Y94 A;  2DFK A;  2D9X A;  2FJL A;  1E5W A;  2LKO A;  3MPX A;  3TW1 A;  2EMS A;  4GXB A;  1K5G B;  1P6S A;  2LUL A;  1P5T A;  1FAO A;  4TYZ A;  2HE7 A;  3LJU X;  3SYX A;  1H10 A;  4F7U P;  3KZ1 A;  1EAZ A;  1MKE A;  3PZD A;  1QQG A;  5DH9 B;  4WJ7 A;  3ULC A;  1W1G A;  3U7D A;  1UNQ A;  2KUP A;  2CY4 A;  3SO6 A;  2QKL A;  1WJ1 A;  1EGX A;  3OAN A;  4P7I A;  5D3X A;  5DHF B;  3WA0 A;  3ODW A;  3TVV A;  1ISN A;  2HTH B;  1XD4 A;  1KI1 B;  2DN6 A;  2MFQ A;  1MAI A;  2ROZ B;  2UVM A;  1FHW A;  4KHB B;  1KZG A;  2KCJ A;  2DX1 A;  1U5D A;  2ROV A;  1XR0 B;  2RUK B;  4GMV A;  1FHO A;  3P7Z A;  5HE0 A;  4EMO A;  2D4Q A;  3HQC A;  3ODX A;  2RSG A;  1BAK A;  4MY6 A;  1DDV A;  1GG3 A;  2J59 M;  5FI1 A;  1X1F A;  5JP4 A;  5JHH A;  2EC1 A;  1ZSQ A;  5J3Y A;  4HAV B;  3UZT A;  3SV1 A;  3X23 A;  2Q13 A;  1UNR A;  5D3W A;  3QWM A;  4HB3 B;  4WSF A;  2J0J A;  5J3T A;  4DX8 A;  1MPH A;  3NSU A;  1EVH A;  1Y19 B;  2LG1 A;  3F0W A;  3PVU A;  3BJI A;  3DXD A;  5GOW B;  1ZC3 B;  2NZ8 B;  1ZM0 A;  3MDB C;  5D3Y A;  1K5D B;  1PLS A;  3PSC A;  4DX9 0;  3AJ4 A;  1MK7 B;  3O96 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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